1     M         0.964   0.988   1.051   1.165   1.194   1.262   0.997   1.038   1.143
2     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
6     V         0.151   0.236  -0.129   0.081   0.208  -0.328   0.156   0.262  -0.368
7     L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
8     L        -0.559  -0.813  -0.854  -0.485  -0.810  -0.909  -0.545  -0.861  -0.940
9     V        -0.851  -0.664  -0.835  -1.064  -0.725  -1.004  -0.994  -0.695  -0.916
10    L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
11    Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
12    E        -1.922  -2.029  -2.115  -1.526  -1.676  -1.878  -1.470  -1.560  -1.530
13    G        -0.558  -0.438  -0.172  -1.094  -0.905  -0.476  -0.966  -0.807  -0.444
14    G         0.151   0.174  -0.100   0.090   0.148  -0.235   0.156   0.176  -0.316
15    K        -1.442  -1.493  -1.390  -1.265  -1.454  -1.308  -1.358  -1.444  -1.249
16    H         0.964   0.988   1.051   1.140   1.172   1.243   0.997   1.038   1.143
17    A         0.462   0.249  -0.078   0.422   0.197  -0.288   0.549   0.280  -0.278
18    E        -2.238  -2.170  -2.116  -1.956  -1.940  -1.912  -1.723  -1.674  -1.530
19    E        -1.111  -1.082  -0.884  -1.235  -1.240  -0.917  -1.246  -1.243  -0.978
20    Q        -0.033  -0.378  -0.817   0.178  -0.199  -0.832   0.128  -0.283  -0.890
21    E        -1.460  -1.665  -2.092  -0.708  -0.967  -1.662  -0.966  -1.168  -1.512
22    K        -0.727  -0.914  -0.867  -0.732  -0.967  -0.917  -0.797  -1.013  -0.961
23    L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
24    L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
25    G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
26    C        -0.261  -0.357  -0.184  -0.051  -0.278  -0.132  -0.461  -0.664  -0.466
27    I        -1.365  -1.570  -1.399  -1.124  -1.505  -1.412  -1.190  -1.444  -1.257
28    E         0.462   0.249  -0.078   0.550   0.338  -0.087   0.549   0.280  -0.278
29    N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
30    E         0.964   0.988   1.051   0.898   0.931   1.060   0.997   1.038   1.143
31    L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
32    G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
33    I        -0.083  -0.101  -0.166  -0.090  -0.130  -0.338  -0.180  -0.237  -0.433
34    R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
35    N        -2.171  -2.037  -1.791  -2.160  -1.964  -1.631  -1.891  -1.721  -1.417
36    F        -1.044  -1.113  -0.898  -0.700  -0.895  -0.725  -1.106  -1.225  -0.995
37    I        -1.189  -1.194  -0.900  -1.412  -1.481  -1.082  -1.302  -1.333  -0.998
38    E         0.964   0.988   1.051   0.898   0.931   1.060   0.997   1.038   1.143
39    E        -0.727  -0.967  -0.878  -0.601  -0.970  -0.912  -0.797  -1.096  -0.972
40    Q        -1.024  -0.979  -1.359  -0.510  -0.532  -1.022  -0.881  -0.890  -1.216
41    G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
42    Y        -0.494  -0.451  -0.190  -0.497  -0.495  -0.148  -0.853  -0.831  -0.476
43    E        -0.494  -0.451  -0.190  -0.717  -0.718  -0.328  -0.853  -0.831  -0.476
44    L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
45    V         0.462   0.402  -0.066   0.418   0.392  -0.220   0.549   0.479  -0.257
46    T        -0.033  -0.017  -0.796   0.278   0.297  -0.709   0.128   0.143  -0.863
47    T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
48    I        -1.922  -2.256  -2.134  -1.378  -1.815  -1.793  -1.470  -1.743  -1.542
49    D        -0.589  -0.392  -0.154  -0.894  -0.588  -0.261  -1.022  -0.726  -0.412
50    K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
51    D        -0.261  -0.215  -0.175  -0.410  -0.347  -0.365  -0.461  -0.422  -0.450
52    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    E        -1.277  -1.489  -1.774  -1.007  -1.259  -1.678  -0.938  -1.167  -1.404
54    P        -2.286  -2.246  -2.130  -2.084  -2.071  -1.898  -1.835  -1.799  -1.540
55    T        -2.148  -2.060  -1.801  -1.946  -1.909  -1.493  -1.835  -1.785  -1.427
56    S         0.964   0.988   1.051   1.043   1.084   1.169   0.997   1.038   1.143
57    T        -1.724  -1.743  -1.767  -1.674  -1.662  -1.625  -1.526  -1.520  -1.399
58    V        -1.322  -1.290  -0.911  -1.533  -1.494  -0.975  -1.470  -1.456  -1.011
59    D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
60    R        -0.811  -0.995  -1.349  -0.546  -0.768  -1.231  -0.601  -0.820  -1.205
61    E        -0.083  -0.141  -0.132  -0.078  -0.185  -0.201  -0.180  -0.301  -0.373
62    L        -0.558  -0.438  -0.172  -0.934  -0.781  -0.368  -0.966  -0.807  -0.444
63    K        -1.808  -2.038  -1.817  -1.609  -1.971  -1.658  -1.470  -1.704  -1.439
64    D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
65    A         0.151   0.114  -0.139   0.103   0.057  -0.312   0.156   0.090  -0.385
66    E        -0.589  -0.392  -0.154  -1.009  -0.672  -0.320  -1.022  -0.726  -0.412
67    I        -0.589  -0.331  -0.144  -1.043  -0.547  -0.314  -1.022  -0.619  -0.393
68    V        -0.397  -0.426  -0.190  -0.717  -0.787  -0.425  -0.685  -0.786  -0.476
69    I         0.964   0.988   1.051   0.937   0.987   1.089   0.997   1.038   1.143
70    T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
71    T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
72    P         0.964   0.988   1.051   1.080   1.110   1.197   0.997   1.038   1.143
73    F         0.964   0.988   1.051   1.198   1.216   1.287   0.997   1.038   1.143
74    F        -0.494  -0.451  -0.190  -0.440  -0.419  -0.084  -0.853  -0.831  -0.476
75    P         0.964   0.988   1.051   1.080   1.110   1.197   0.997   1.038   1.143
76    A        -0.558  -0.458  -0.185  -1.100  -0.949  -0.500  -0.966  -0.844  -0.467
77    Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
78    I        -0.559  -0.813  -0.854  -0.467  -0.814  -0.988  -0.545  -0.861  -0.940
79    S        -0.987  -0.856  -0.847  -1.030  -0.765  -0.762  -1.218  -0.960  -0.934
80    R        -0.851  -0.952  -0.865  -0.942  -1.046  -0.944  -0.994  -1.071  -0.958
81    N         0.462   0.335  -0.075   0.545   0.423  -0.108   0.549   0.394  -0.273
82    R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
83    I         0.462   0.249  -0.078   0.569   0.356  -0.165   0.549   0.280  -0.278
84    A        -0.987  -0.698  -0.825  -1.310  -0.821  -0.912  -1.218  -0.789  -0.901
85    E        -0.518  -0.857  -1.347  -0.217  -0.583  -1.247  -0.265  -0.649  -1.203
86    A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
87    P        -0.494  -0.451  -0.190  -0.752  -0.697  -0.304  -0.853  -0.831  -0.476
88    N        -0.851  -0.845  -0.856  -0.929  -0.913  -0.894  -0.994  -0.977  -0.949
89    L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
90    K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
91    L        -1.111  -1.082  -0.884  -1.204  -1.241  -0.917  -1.246  -1.243  -0.978
92    C         0.462   0.249  -0.078   0.848   0.610   0.021   0.549   0.280  -0.278
93    V        -0.261  -0.310  -0.186  -0.386  -0.506  -0.410  -0.461  -0.583  -0.469
94    T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
95    A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
96    G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
97    V         0.462   0.249  -0.078   0.418   0.223  -0.240   0.549   0.280  -0.278
98    G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
99    S         0.964   0.988   1.051   1.043   1.084   1.169   0.997   1.038   1.143
100   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
101   H         0.964   0.988   1.051   1.140   1.172   1.243   0.997   1.038   1.143
102   V        -0.559  -0.615  -0.842  -0.546  -0.627  -0.912  -0.545  -0.655  -0.924
103   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
104   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
105   E        -0.811  -1.050  -1.369  -0.535  -0.833  -1.340  -0.601  -0.901  -1.228
106   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
107   A        -0.083  -0.141  -0.132  -0.233  -0.346  -0.367  -0.180  -0.301  -0.373
108   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
109   E        -0.987  -0.898  -0.839  -1.297  -1.025  -0.971  -1.218  -0.989  -0.920
110   R        -0.033  -0.246  -0.806   0.333   0.097  -0.736   0.128  -0.133  -0.876
111   K        -1.896  -1.869  -1.425  -2.013  -2.046  -1.452  -1.779  -1.752  -1.281
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   I         0.462   0.417  -0.065   0.566   0.543  -0.157   0.549   0.497  -0.256
115   T        -0.335  -0.432  -0.851  -0.248  -0.442  -0.916  -0.237  -0.449  -0.938
116   V         0.462   0.444  -0.065   0.409   0.422  -0.267   0.549   0.531  -0.256
117   T        -1.024  -1.279  -1.377  -0.881  -1.233  -1.400  -0.881  -1.167  -1.236
118   E         0.964   0.988   1.051   0.898   0.931   1.060   0.997   1.038   1.143
119   V         0.964   0.988   1.051   0.780   0.839   0.970   0.997   1.038   1.143
120   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
121   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
122   S         0.964   0.988   1.051   1.043   1.084   1.169   0.997   1.038   1.143
123   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
124   V         0.964   0.988   1.051   0.780   0.839   0.970   0.997   1.038   1.143
125   V        -0.851  -0.840  -0.864  -0.774  -0.888  -0.873  -0.994  -1.033  -0.958
126   S         0.964   0.988   1.051   1.043   1.084   1.169   0.997   1.038   1.143
127   V         0.964   0.988   1.051   0.780   0.839   0.970   0.997   1.038   1.143
128   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
129   E         0.964   0.988   1.051   0.898   0.931   1.060   0.997   1.038   1.143
130   H         0.964   0.988   1.051   1.140   1.172   1.243   0.997   1.038   1.143
131   V        -0.083  -0.141  -0.132  -0.255  -0.352  -0.392  -0.180  -0.301  -0.373
132   M        -1.487  -1.601  -1.399  -1.535  -1.706  -1.408  -1.386  -1.505  -1.259
133   A         0.462   0.335  -0.075   0.795   0.661  -0.010   0.549   0.394  -0.273
134   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
135   I         0.151  -0.079  -0.162   0.466   0.137  -0.138   0.156  -0.203  -0.426
136   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
137   V        -0.083  -0.141  -0.132  -0.224  -0.305  -0.333  -0.180  -0.301  -0.373
138   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
139   I        -0.628  -0.800  -0.872  -0.626  -0.867  -1.053  -0.573  -0.815  -0.963
140   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
141   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
142   Y        -0.261  -0.329  -0.177  -0.045  -0.221  -0.087  -0.461  -0.616  -0.454
143   N        -0.628  -0.798  -0.877  -0.615  -0.844  -1.024  -0.573  -0.814  -0.969
144   G        -0.559  -0.738  -0.853  -0.303  -0.573  -0.869  -0.545  -0.780  -0.938
145   G        -0.261  -0.329  -0.177  -0.529  -0.689  -0.484  -0.461  -0.616  -0.454
146   H         0.462   0.503  -0.068   0.787   0.831   0.072   0.549   0.600  -0.261
147   Q        -0.559  -0.738  -0.853  -0.479  -0.736  -0.898  -0.545  -0.780  -0.938
148   Q         0.964   0.988   1.051   1.139   1.162   1.243   0.997   1.038   1.143
149   A        -1.406  -1.288  -0.915  -1.777  -1.654  -1.136  -1.582  -1.452  -1.016
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   I        -2.169  -2.183  -2.124  -1.699  -1.758  -1.696  -1.695  -1.703  -1.535
152   N        -2.986  -2.781  -2.409  -2.749  -2.510  -2.072  -2.255  -2.032  -1.621
153   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
154   E        -1.487  -1.694  -1.416  -1.520  -1.797  -1.411  -1.386  -1.592  -1.274
155   W         0.964   0.988   1.051   1.242   1.262   1.321   0.997   1.038   1.143
156   D         0.151   0.317  -0.101   0.196   0.410  -0.164   0.156   0.370  -0.318
157   I        -0.397  -0.403  -0.184  -0.717  -0.746  -0.419  -0.685  -0.745  -0.465
158   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
159   G        -0.727  -0.918  -0.869  -0.885  -1.148  -1.098  -0.797  -1.019  -0.963
160   V        -0.083  -0.175  -0.167  -0.255  -0.409  -0.460  -0.180  -0.357  -0.435
161   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
162   K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
163   N         0.151  -0.079  -0.162   0.196  -0.089  -0.263   0.156  -0.203  -0.426
164   E        -0.558  -0.438  -0.172  -0.805  -0.670  -0.276  -0.966  -0.807  -0.444
165   Y        -0.261  -0.357  -0.184  -0.124  -0.321  -0.112  -0.461  -0.664  -0.466
166   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
167   L        -0.999  -0.906  -0.861  -1.059  -0.917  -0.886  -1.078  -0.959  -0.949
168   E         0.964   0.988   1.051   0.898   0.931   1.060   0.997   1.038   1.143
169   D        -0.397  -0.395  -0.182  -0.751  -0.758  -0.455  -0.685  -0.731  -0.463
170   K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
171   I         0.462   0.335  -0.075   0.418   0.320  -0.235   0.549   0.394  -0.273
172   I        -0.335  -0.620  -0.825  -0.094  -0.423  -0.794  -0.237  -0.590  -0.901
173   S        -0.851  -0.937  -0.879  -1.114  -1.214  -1.063  -0.994  -1.090  -0.974
174   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
175   V         0.151   0.075  -0.098   0.081   0.005  -0.275   0.156   0.033  -0.314
176   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
177   A        -1.288  -1.276  -0.908  -1.718  -1.748  -1.205  -1.442  -1.439  -1.007
178   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
179   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
180   I         0.964   0.988   1.051   0.937   0.987   1.089   0.997   1.038   1.143
181   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
182   Y        -1.367  -1.402  -1.392  -1.133  -1.190  -1.216  -1.386  -1.370  -1.250
183   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
184   V        -0.083  -0.141  -0.132  -0.224  -0.305  -0.333  -0.180  -0.301  -0.373
185   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
186   E        -1.367  -1.402  -1.392  -1.438  -1.432  -1.289  -1.386  -1.370  -1.250
187   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
188   L        -1.183  -0.702  -0.813  -1.294  -0.651  -0.841  -1.358  -0.732  -0.886
189   V        -1.896  -1.769  -1.425  -2.099  -1.986  -1.555  -1.779  -1.659  -1.281
190   A        -0.494  -0.451  -0.190  -0.687  -0.714  -0.335  -0.853  -0.831  -0.476
191   F         0.964   0.988   1.051   1.198   1.216   1.287   0.997   1.038   1.143
192   N        -0.589  -0.414  -0.176  -0.875  -0.580  -0.258  -1.022  -0.765  -0.451
193   P         0.462   0.249  -0.078   0.736   0.527   0.064   0.549   0.280  -0.278
194   K        -0.558  -0.241  -0.120  -0.805  -0.331  -0.172  -0.966  -0.466  -0.351
195   K        -0.494  -0.451  -0.190  -0.824  -0.815  -0.406  -0.853  -0.831  -0.476
196   L        -0.589  -0.308  -0.131  -0.857  -0.459  -0.202  -1.022  -0.580  -0.370
197   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
198   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
199   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
200   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
201   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
202   Q         0.964   0.988   1.051   1.139   1.162   1.243   0.997   1.038   1.143
203   E        -1.985  -1.672  -1.765  -1.711  -1.261  -1.634  -1.667  -1.326  -1.396
204   L        -0.558  -0.241  -0.120  -0.822  -0.358  -0.186  -0.966  -0.466  -0.351
205   P        -0.261  -0.223  -0.169  -0.170  -0.142  -0.159  -0.461  -0.435  -0.439
206   A        -1.044  -1.030  -0.889  -1.205  -1.240  -1.082  -1.106  -1.119  -0.983
207   E        -1.004  -0.782  -0.849  -1.286  -0.921  -0.980  -1.246  -0.937  -0.937
208   A        -2.102  -2.028  -1.798  -2.264  -2.141  -1.796  -1.863  -1.733  -1.425
209   I        -0.494  -0.451  -0.190  -0.782  -0.755  -0.359  -0.853  -0.831  -0.476
210   N        -2.354  -2.153  -2.114  -2.139  -1.944  -1.830  -1.919  -1.743  -1.529
211   R        -0.851  -0.937  -0.879  -0.965  -1.095  -0.957  -0.994  -1.090  -0.974
212   L        -0.589  -0.449  -0.184  -1.007  -0.800  -0.388  -1.022  -0.827  -0.465
213   N        -0.589  -0.449  -0.184  -0.972  -0.722  -0.330  -1.022  -0.827  -0.465
214   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   V        -1.294  -1.289  -1.385  -1.056  -1.144  -1.313  -1.274  -1.278  -1.246
227   Q        -0.851  -0.937  -0.879  -0.789  -0.931  -0.822  -0.994  -1.090  -0.974
228   R         0.462   0.546  -0.065   0.709   0.791   0.044   0.549   0.649  -0.256
229   V         0.964   0.988   1.051   0.780   0.839   0.970   0.997   1.038   1.143
230   E        -0.033  -0.179  -0.804   0.175  -0.003  -0.827   0.128  -0.062  -0.873
231   K        -1.598  -1.541  -1.391  -1.598  -1.547  -1.319  -1.582  -1.496  -1.251
232   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
233   E         0.462   0.546  -0.065   0.531   0.619  -0.162   0.549   0.649  -0.256
234   D        -0.987  -0.664  -0.853  -1.221  -0.798  -0.881  -1.218  -0.852  -0.941
235   M        -0.559  -0.491  -0.838  -0.227  -0.238  -0.782  -0.545  -0.540  -0.918
236   V        -0.494  -0.451  -0.190  -0.922  -0.905  -0.485  -0.853  -0.831  -0.476
237   A        -1.111  -1.056  -0.883  -1.197  -1.193  -1.017  -1.246  -1.203  -0.979
238   Q        -0.937  -0.528  -0.808  -0.953  -0.291  -0.759  -1.134  -0.557  -0.879
239   S        -0.851  -0.937  -0.879  -0.690  -0.860  -0.815  -0.994  -1.090  -0.974
240   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
241   V        -0.559  -0.359  -0.823  -0.588  -0.304  -0.972  -0.545  -0.286  -0.900
242   V         0.964   0.988   1.051   0.780   0.839   0.970   0.997   1.038   1.143
243   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
244   I         0.462   0.417  -0.065   0.569   0.546  -0.141   0.549   0.497  -0.256
245   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
246   C         0.964   0.988   1.051   1.218   1.246   1.302   0.997   1.038   1.143
247   P         0.964   0.988   1.051   1.080   1.110   1.197   0.997   1.038   1.143
248   L         0.964   0.988   1.051   0.832   0.870   1.009   0.997   1.038   1.143
249   H        -0.083  -0.141  -0.132   0.162   0.050  -0.037  -0.180  -0.301  -0.373
250   K        -1.367  -1.113  -1.342  -1.506  -1.034  -1.378  -1.386  -1.005  -1.198
251   D        -0.851  -0.960  -0.866  -0.844  -1.039  -0.922  -0.994  -1.126  -0.960
252   S        -0.494  -0.451  -0.190  -0.647  -0.618  -0.249  -0.853  -0.831  -0.476
253   R        -0.335  -0.646  -0.851  -0.173  -0.524  -0.820  -0.237  -0.625  -0.936
254   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
255   L         0.151   0.172  -0.150   0.165   0.193  -0.230   0.156   0.172  -0.405
256   F         0.964   0.988   1.051   1.198   1.216   1.287   0.997   1.038   1.143
257   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
258   K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
259   K        -0.999  -0.965  -0.897  -1.073  -1.077  -1.044  -1.078  -1.068  -0.993
260   L         0.151   0.350  -0.080   0.165   0.390  -0.126   0.156   0.414  -0.281
261   I        -0.083   0.094  -0.117  -0.090   0.157  -0.238  -0.180   0.061  -0.345
262   S         0.964   0.988   1.051   1.043   1.084   1.169   0.997   1.038   1.143
263   H        -0.494  -0.457  -0.189  -0.604  -0.640  -0.273  -0.853  -0.841  -0.475
264   M         0.964   0.988   1.051   1.165   1.194   1.262   0.997   1.038   1.143
265   K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
266   D        -0.987  -0.732  -0.860  -1.257  -0.969  -0.945  -1.218  -0.973  -0.954
267   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
268   A        -0.261  -0.357  -0.184  -0.446  -0.621  -0.356  -0.461  -0.664  -0.466
269   Y        -0.261  -0.329  -0.177  -0.003  -0.180  -0.061  -0.461  -0.616  -0.454
270   L        -0.033  -0.154  -0.794   0.088  -0.037  -0.954   0.128  -0.015  -0.859
271   V         0.151   0.075  -0.098   0.081   0.005  -0.275   0.156   0.033  -0.314
272   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
273   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
274   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
275   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
276   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
277   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
278   I         0.151   0.075  -0.098   0.225   0.131  -0.203   0.156   0.033  -0.314
279   C        -0.628  -0.853  -0.876  -0.188  -0.554  -0.814  -0.573  -0.886  -0.969
280   V        -0.083  -0.141  -0.132  -0.238  -0.320  -0.358  -0.180  -0.301  -0.373
281   A        -1.997  -1.898  -1.424  -2.084  -2.026  -1.412  -1.891  -1.780  -1.280
282   E        -0.335  -0.347  -0.812  -0.135  -0.174  -0.790  -0.237  -0.291  -0.884
283   D        -0.083  -0.141  -0.132  -0.158  -0.254  -0.326  -0.180  -0.301  -0.373
284   V        -0.589  -0.441  -0.180  -1.043  -0.812  -0.414  -1.022  -0.813  -0.459
285   A        -0.558  -0.241  -0.120  -1.088  -0.527  -0.364  -0.966  -0.466  -0.351
286   E        -1.288  -1.159  -0.907  -1.554  -1.399  -1.087  -1.442  -1.297  -1.006
287   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
288   V        -0.494  -0.451  -0.190  -0.922  -0.905  -0.485  -0.853  -0.831  -0.476
289   K        -1.744  -1.421  -1.366  -1.897  -1.453  -1.356  -1.723  -1.379  -1.223
290   S        -0.335  -0.015  -0.796  -0.004   0.340  -0.709  -0.237   0.129  -0.862
291   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
292   K        -1.189  -1.100  -0.895  -1.212  -1.123  -0.830  -1.302  -1.243  -0.992
293   L        -0.987  -0.733  -0.861  -1.211  -0.949  -0.895  -1.218  -0.974  -0.954
294   A         0.386   0.134  -0.111   0.610   0.302  -0.154   0.460   0.120  -0.336
295   G        -0.083  -0.141  -0.132  -0.265  -0.351  -0.399  -0.180  -0.301  -0.373
296   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
297   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
298   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
299   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
300   V         0.964   0.988   1.051   0.780   0.839   0.970   0.997   1.038   1.143
301   W         0.964   0.988   1.051   1.242   1.262   1.321   0.997   1.038   1.143
302   D        -1.739  -1.803  -1.801  -1.122  -1.294  -1.391  -1.442  -1.520  -1.425
303   K        -0.559  -0.738  -0.853  -0.323  -0.595  -0.888  -0.545  -0.780  -0.938
304   Q         0.964   0.988   1.051   1.139   1.162   1.243   0.997   1.038   1.143
305   P         0.964   0.988   1.051   1.080   1.110   1.197   0.997   1.038   1.143
306   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
307   P         0.462   0.613  -0.063   0.725   0.868   0.030   0.549   0.723  -0.253
308   K        -0.559  -0.602  -0.837  -0.524  -0.518  -0.900  -0.545  -0.566  -0.918
309   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
310   H        -0.083  -0.141  -0.132   0.180   0.078  -0.003  -0.180  -0.301  -0.373
311   P         0.964   0.988   1.051   1.080   1.110   1.197   0.997   1.038   1.143
312   W         0.462   0.249  -0.078   0.875   0.631   0.050   0.549   0.280  -0.278
313   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
314   T        -1.991  -1.891  -2.109  -1.410  -1.344  -1.703  -1.498  -1.417  -1.525
315   M         0.462   0.249  -0.078   0.795   0.559  -0.016   0.549   0.280  -0.278
316   D        -2.169  -2.384  -2.146  -1.600  -1.941  -1.787  -1.695  -1.857  -1.550
317   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
318   K        -0.727  -0.655  -0.864  -0.711  -0.728  -0.850  -0.797  -0.837  -0.957
319   D        -0.518  -0.793  -1.345   0.031  -0.288  -1.019  -0.265  -0.587  -1.201
320   H        -0.033  -0.163  -0.803   0.069  -0.021  -0.800   0.128  -0.028  -0.871
321   V        -1.956  -1.997  -1.800  -2.108  -2.152  -1.897  -1.723  -1.703  -1.426
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
325   N         0.964   0.988   1.051   1.067   1.086   1.187   0.997   1.038   1.143
326   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
327   M         0.964   0.988   1.051   1.165   1.194   1.262   0.997   1.038   1.143
328   T         0.462   0.249  -0.078   0.620   0.390  -0.144   0.549   0.280  -0.278
329   V        -0.559  -0.690  -0.863  -0.325  -0.572  -0.925  -0.545  -0.754  -0.953
330   H         0.964   0.988   1.051   1.140   1.172   1.243   0.997   1.038   1.143
331   I        -1.111  -1.162  -0.910  -1.228  -1.322  -0.959  -1.246  -1.314  -1.009
332   S         0.964   0.988   1.051   1.043   1.084   1.169   0.997   1.038   1.143
333   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
334   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
335   S         0.462   0.588  -0.063   0.699   0.828   0.062   0.549   0.696  -0.252
336   L        -0.589  -0.384  -0.152  -1.007  -0.684  -0.332  -1.022  -0.712  -0.407
337   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
338   A         0.964   0.988   1.051   0.794   0.833   0.981   0.997   1.038   1.143
339   Q         0.964   0.988   1.051   1.139   1.162   1.243   0.997   1.038   1.143
340   K        -1.617  -1.479  -1.386  -1.943  -1.731  -1.564  -1.611  -1.443  -1.245
341   R         0.964   0.988   1.051   1.058   1.086   1.181   0.997   1.038   1.143
342   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
343   A         0.462   0.546  -0.065   0.439   0.532  -0.172   0.549   0.649  -0.256
344   Q        -2.103  -2.113  -1.818  -1.927  -2.006  -1.620  -1.807  -1.801  -1.440
345   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
346   V        -0.558  -0.457  -0.183  -0.918  -0.808  -0.391  -0.966  -0.842  -0.464
347   K         0.964   0.988   1.051   0.853   0.899   1.025   0.997   1.038   1.143
348   N        -2.331  -2.247  -1.799  -2.206  -2.056  -1.524  -2.031  -1.889  -1.426
349   I         0.964   0.988   1.051   0.937   0.987   1.089   0.997   1.038   1.143
350   L         0.462   0.249  -0.078   0.470   0.254  -0.203   0.549   0.280  -0.278
351   N        -1.733  -1.683  -1.418  -1.665  -1.669  -1.345  -1.611  -1.583  -1.274
352   S        -1.737  -1.592  -1.403  -1.875  -1.703  -1.316  -1.695  -1.577  -1.262
353   Y        -0.589  -0.392  -0.154  -0.641  -0.379  -0.065  -1.022  -0.726  -0.412
354   F         0.462   0.249  -0.078   0.831   0.585   0.019   0.549   0.280  -0.278
355   S        -0.811  -0.923  -1.354  -0.356  -0.501  -1.170  -0.601  -0.745  -1.211
356   K        -0.261  -0.329  -0.177  -0.528  -0.655  -0.458  -0.461  -0.616  -0.454
357   K        -0.559  -0.590  -0.843  -0.485  -0.559  -0.861  -0.545  -0.631  -0.925
358   F        -2.169  -2.331  -2.141  -1.477  -1.758  -1.572  -1.695  -1.835  -1.547
359   D        -1.479  -1.472  -1.765  -1.135  -1.101  -1.503  -1.190  -1.162  -1.398
360   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
361   R         0.462   0.486  -0.065   0.690   0.716  -0.054   0.549   0.580  -0.255
362   P         0.964   0.988   1.051   1.080   1.110   1.197   0.997   1.038   1.143
363   Q        -0.033  -0.236  -0.803   0.409   0.170  -0.706   0.128  -0.122  -0.872
364   D         0.964   0.988   1.051   0.877   0.938   1.043   0.997   1.038   1.143
365   I        -0.937  -1.030  -0.870  -1.158  -1.265  -1.043  -1.134  -1.195  -0.965
366   I         0.964   0.988   1.051   0.937   0.987   1.089   0.997   1.038   1.143
367   V        -1.111  -1.142  -0.883  -1.011  -1.186  -0.896  -1.246  -1.300  -0.977
368   Q        -0.335  -0.594  -0.853  -0.086  -0.382  -0.766  -0.237  -0.571  -0.940
369   N        -1.111  -1.162  -0.910  -1.137  -1.290  -1.014  -1.246  -1.314  -1.009
370   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
371   S        -1.294  -1.354  -1.373  -1.052  -1.189  -1.175  -1.274  -1.336  -1.234
372   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
373   A        -0.558  -0.438  -0.172  -1.100  -0.906  -0.472  -0.966  -0.807  -0.444
374   T         0.964   0.988   1.051   0.991   1.025   1.130   0.997   1.038   1.143
375   R         0.462   0.335  -0.075   0.499   0.391  -0.142   0.549   0.394  -0.273
376   A         0.151   0.009  -0.151   0.111  -0.070  -0.310   0.156  -0.067  -0.407
377   Y         0.964   0.988   1.051   1.079   1.098   1.197   0.997   1.038   1.143
378   G         0.964   0.988   1.051   0.770   0.840   0.963   0.997   1.038   1.143
379   Q        -0.937  -1.032  -0.881  -1.013  -1.058  -0.866  -1.134  -1.198  -0.976
380   -        -0.522  -0.453  -0.179  -0.790  -0.668  -0.271  -0.902  -0.835  -0.457
381   -         0.280  -0.214  -0.164   0.303  -0.378  -0.351   0.328  -0.421  -0.430
382   -        -0.384  -0.901  -0.899  -0.178  -0.910  -0.963  -0.275  -0.982  -0.996
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.765  -1.531  -1.410  -1.969  -1.699  -1.578  -1.704  -1.446  -1.267
390   -        -0.384  -0.901  -0.899  -0.015  -0.816  -0.983  -0.275  -0.982  -0.996
391   -        -3.458  -3.263  -2.660  -3.040  -2.864  -2.241  -2.424  -2.217  -1.686
392   K        -2.003  -1.411  -1.764  -1.912  -1.194  -1.611  -1.725  -1.181  -1.397
393   K         0.462   0.249  -0.078   0.482   0.263  -0.238   0.549   0.280  -0.278
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08911
Output conservation file - output/Q08911
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
