1     M         1.912   1.916   2.012   2.155   2.159   2.307   2.120   2.126   2.283
2     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    N        -1.033  -1.031  -0.955  -1.054  -1.037  -0.936  -0.964  -0.961  -0.854
12    D        -0.297  -0.295  -0.267  -0.462  -0.429  -0.416  -0.450  -0.446  -0.406
13    Y         1.912   1.916   2.012   2.214   2.223   2.367   2.120   2.126   2.283
14    S        -1.033  -1.031  -0.955  -1.202  -1.193  -1.086  -0.964  -0.961  -0.854
15    T        -0.297  -0.295  -0.264  -0.219  -0.211  -0.174  -0.450  -0.446  -0.402
16    M        -1.033  -1.031  -0.955  -0.770  -0.773  -0.650  -0.964  -0.961  -0.854
17    I         1.912   1.916   2.012   2.038   2.048   2.189   2.120   2.126   2.283
18    D         0.717   0.730   0.679   0.622   0.652   0.502   0.578   0.599   0.480
19    I        -1.033  -1.031  -0.955  -1.016  -0.999  -0.898  -0.964  -0.961  -0.854
20    L         0.717   0.711   0.674   0.797   0.771   0.693   0.578   0.566   0.471
21    L         1.912   1.916   2.012   1.774   1.751   1.922   2.120   2.126   2.283
22    S        -0.297  -0.282  -0.268  -0.281  -0.214  -0.248  -0.450  -0.429  -0.408
23    D        -0.297  -0.306  -0.276  -0.222  -0.235  -0.197  -0.450  -0.463  -0.419
24    M        -0.297  -0.295  -0.276  -0.176  -0.191  -0.131  -0.450  -0.446  -0.418
25    D         0.717   0.711   0.689   0.785   0.790   0.736   0.578   0.566   0.498
26    L         0.717   0.730   0.679   0.622   0.599   0.562   0.578   0.599   0.480
27    E        -0.297  -0.282  -0.268  -0.446  -0.383  -0.398  -0.450  -0.429  -0.408
28    T         0.717   0.711   0.689   0.798   0.798   0.746   0.578   0.566   0.498
29    V         0.717   0.730   0.694   0.868   0.893   0.827   0.578   0.599   0.507
30    T         0.440   0.443   0.529   0.297   0.332   0.430   0.064   0.069   0.193
31    T        -1.033  -1.031  -0.955  -0.875  -0.897  -0.756  -0.964  -0.961  -0.854
32    K         1.912   1.916   2.012   1.517   1.515   1.662   2.120   2.126   2.283
33    K        -0.297  -0.282  -0.268  -0.643  -0.638  -0.589  -0.450  -0.429  -0.408
34    V         0.440   0.442   0.529   0.406   0.410   0.540   0.064   0.068   0.193
35    R         1.912   1.916   2.012   2.026   2.021   2.177   2.120   2.126   2.283
36    M        -0.297  -0.306  -0.276  -0.088  -0.086  -0.050  -0.450  -0.463  -0.419
37    A        -0.297  -0.282  -0.268  -0.576  -0.590  -0.575  -0.450  -0.429  -0.408
38    L         0.717   0.730   0.694   0.674   0.654   0.653   0.578   0.599   0.507
39    K        -0.297  -0.306  -0.276  -0.637  -0.623  -0.630  -0.450  -0.463  -0.419
40    E         0.717   0.730   0.694   0.524   0.573   0.475   0.578   0.599   0.507
41    V        -1.033  -1.031  -0.955  -0.978  -1.022  -0.860  -0.964  -0.961  -0.854
42    Y        -1.033  -1.031  -0.955  -0.596  -0.619  -0.473  -0.964  -0.961  -0.854
43    A        -1.033  -1.031  -0.955  -1.047  -1.068  -0.929  -0.964  -0.961  -0.854
44    I        -0.297  -0.295  -0.267  -0.340  -0.340  -0.324  -0.450  -0.446  -0.406
45    D         0.717   0.711   0.689   0.785   0.790   0.736   0.578   0.566   0.498
46    V         0.717   0.711   0.674   0.622   0.580   0.555   0.578   0.566   0.471
47    E        -0.297  -0.306  -0.276  -0.556  -0.534  -0.580  -0.450  -0.463  -0.419
48    S        -1.033  -1.031  -0.955  -0.938  -0.883  -0.819  -0.964  -0.961  -0.854
49    Q         0.440   0.442   0.528   0.503   0.523   0.638   0.064   0.068   0.192
50    G         0.717   0.711   0.674   0.412   0.386   0.367   0.578   0.566   0.471
51    K         0.717   0.730   0.694   0.433   0.436   0.420   0.578   0.599   0.507
52    A        -0.297  -0.295  -0.268  -0.413  -0.410  -0.388  -0.450  -0.446  -0.407
53    I         0.717   0.730   0.679   0.797   0.803   0.702   0.578   0.599   0.480
54    N         0.717   0.730   0.694   0.712   0.739   0.623   0.578   0.599   0.507
55    K        -1.033  -1.031  -0.955  -1.232  -1.251  -1.116  -0.964  -0.961  -0.854
56    L         0.717   0.711   0.689   0.622   0.580   0.577   0.578   0.566   0.498
57    I         1.912   1.916   2.012   2.038   2.048   2.189   2.120   2.126   2.283
58    R        -0.297  -0.295  -0.267  -0.485  -0.512  -0.450  -0.450  -0.446  -0.406
59    K        -0.297  -0.295  -0.264  -0.784  -0.793  -0.742  -0.450  -0.446  -0.402
60    H        -0.297  -0.295  -0.276   0.025   0.010   0.077  -0.450  -0.446  -0.418
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    L        -0.297  -0.306  -0.276  -0.030  -0.077  -0.013  -0.450  -0.463  -0.419
63    D         1.912   1.916   2.012   1.941   1.966   2.091   2.120   2.126   2.283
64    L        -0.297  -0.282  -0.268  -0.544  -0.551  -0.518  -0.450  -0.429  -0.408
65    V        -0.297  -0.282  -0.268  -0.214  -0.196  -0.184  -0.450  -0.429  -0.408
66    K        -1.033  -1.031  -0.955  -1.128  -1.136  -1.012  -0.964  -0.961  -0.854
67    E        -0.297  -0.306  -0.276  -0.602  -0.636  -0.625  -0.450  -0.463  -0.419
68    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   E        -0.297  -0.295  -0.268  -0.688  -0.675  -0.672  -0.450  -0.446  -0.407
110   D        -1.033  -1.031  -0.955  -1.036  -0.958  -0.919  -0.964  -0.961  -0.854
111   L        -1.033  -1.031  -0.955  -1.022  -1.031  -0.905  -0.964  -0.961  -0.854
112   L        -0.107  -0.138  -0.227  -0.202  -0.220  -0.393  -0.182  -0.226  -0.351
113   K        -0.107  -0.116  -0.162  -0.351  -0.406  -0.416  -0.182  -0.196  -0.258
114   E        -0.918  -0.925  -0.920  -0.808  -0.788  -0.838  -0.840  -0.848  -0.817
115   N        -0.107  -0.138  -0.227  -0.076  -0.115  -0.320  -0.182  -0.226  -0.351
116   A         0.849   0.840   0.721   0.964   0.938   0.795   0.804   0.788   0.557
117   T        -0.918  -0.925  -0.920  -1.037  -1.132  -1.053  -0.840  -0.848  -0.817
118   L        -0.107  -0.064  -0.182  -0.027  -0.040  -0.112  -0.182  -0.123  -0.287
119   A         1.912   1.916   2.012   1.908   1.905   2.057   2.120   2.126   2.283
120   I        -0.918  -0.905  -0.906  -0.721  -0.723  -0.690  -0.840  -0.826  -0.801
121   E        -0.107  -0.085  -0.168  -0.288  -0.228  -0.411  -0.182  -0.154  -0.267
122   L         0.849   0.840   0.721   0.817   0.756   0.633   0.804   0.788   0.557
123   T        -1.507  -1.502  -1.433  -1.243  -1.213  -1.127  -1.169  -1.163  -1.063
124   K        -0.918  -0.929  -0.891  -1.098  -1.164  -1.034  -0.840  -0.852  -0.786
125   E        -0.107  -0.034  -0.160  -0.169   0.021  -0.245  -0.182  -0.081  -0.255
126   -         0.717   0.758   0.669   0.589   0.732   0.511   0.578   0.648   0.460
127   -        -1.033  -1.030  -0.955  -0.748  -0.758  -0.628  -0.964  -0.959  -0.854
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   I        -0.918  -0.938  -0.890  -1.018  -1.085  -0.944  -0.840  -0.861  -0.785
142   T        -0.913  -0.880  -0.888  -1.095  -1.119  -1.039  -0.849  -0.819  -0.788
143   V        -0.913  -0.880  -0.884  -0.743  -0.703  -0.703  -0.849  -0.818  -0.784
144   S        -1.895  -1.888  -1.823  -1.376  -1.379  -1.262  -1.306  -1.300  -1.202
145   K         0.955   0.940   0.783   0.703   0.648   0.508   0.978   0.954   0.669
146   R         0.955   0.942   0.796   1.084   1.032   0.804   0.978   0.957   0.693
147   S         0.482   0.498   0.543   0.367   0.415   0.449   0.146   0.174   0.221
148   S        -1.507  -1.503  -1.433  -1.344  -1.382  -1.230  -1.169  -1.164  -1.063
149   G        -0.918  -0.917  -0.900  -0.991  -1.016  -0.917  -0.840  -0.838  -0.795
150   E        -0.107  -0.144  -0.193  -0.457  -0.528  -0.591  -0.182  -0.235  -0.303
151   E        -0.329  -0.330  -0.290  -0.691  -0.656  -0.663  -0.511  -0.511  -0.444
152   K         0.717   0.763   0.676   0.230   0.298   0.132   0.578   0.657   0.473
153   N        -0.918  -0.935  -0.906  -0.896  -0.916  -0.903  -0.840  -0.858  -0.801
154   D        -0.913  -0.936  -0.901  -0.614  -0.597  -0.574  -0.849  -0.869  -0.801
155   S        -0.728  -0.714  -0.830  -0.982  -0.965  -1.122  -0.621  -0.607  -0.717
156   E        -0.237  -0.193  -0.253  -0.730  -0.686  -0.736  -0.393  -0.350  -0.398
157   T        -1.404  -1.382  -1.382  -1.412  -1.404  -1.334  -1.078  -1.058  -1.019
158   K        -0.237  -0.247  -0.238  -0.554  -0.565  -0.514  -0.393  -0.404  -0.377
159   G        -1.404  -1.380  -1.384  -1.342  -1.355  -1.259  -1.078  -1.055  -1.021
160   T        -0.422  -0.415  -0.336  -0.680  -0.677  -0.529  -0.621  -0.612  -0.501
161   H        -0.728  -0.710  -0.807  -0.811  -0.818  -0.874  -0.621  -0.602  -0.692
162   V        -0.728  -0.665  -0.811  -0.380  -0.284  -0.504  -0.621  -0.548  -0.696
163   E        -0.728  -0.782  -0.853  -0.962  -1.066  -1.125  -0.621  -0.684  -0.743
164   K        -1.404  -1.427  -1.389  -1.367  -1.348  -1.367  -1.078  -1.098  -1.025
165   K         0.440   0.443   0.528  -0.042  -0.034   0.085   0.064   0.070   0.192
166   K        -1.404  -1.401  -1.382  -1.254  -1.218  -1.234  -1.078  -1.075  -1.019
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   G        -0.297  -0.266  -0.268  -0.035   0.031   0.003  -0.450  -0.407  -0.407
178   T         0.717   0.770   0.677   0.776   0.868   0.692   0.578   0.669   0.476
179   V         0.717   0.698   0.637   0.386   0.333   0.269   0.578   0.543   0.401
180   S        -1.033  -1.029  -0.955  -1.142  -1.136  -1.026  -0.964  -0.959  -0.854
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   K        -0.913  -0.918  -0.888  -0.858  -0.891  -0.832  -0.849  -0.853  -0.789
184   S         0.069   0.019  -0.113   0.381   0.337   0.130   0.064  -0.006  -0.189
185   P        -0.913  -0.936  -0.886  -0.673  -0.642  -0.607  -0.849  -0.870  -0.786
186   I        -0.913  -0.923  -0.900  -0.645  -0.658  -0.592  -0.849  -0.857  -0.799
187   S        -0.728  -0.782  -0.853  -0.276  -0.363  -0.483  -0.621  -0.684  -0.743
188   T        -1.404  -1.424  -1.374  -1.006  -1.048  -0.955  -1.078  -1.096  -1.012
189   R        -0.237  -0.209  -0.252  -0.521  -0.542  -0.494  -0.393  -0.355  -0.397
190   K        -0.422  -0.415  -0.337  -0.846  -0.794  -0.722  -0.621  -0.612  -0.501
191   V        -0.913  -0.905  -0.885  -0.494  -0.498  -0.431  -0.849  -0.840  -0.786
192   T        -1.895  -1.888  -1.823  -1.488  -1.514  -1.375  -1.306  -1.300  -1.202
193   L         1.912   1.916   2.012   1.790   1.757   1.939   2.120   2.126   2.283
194   S         1.912   1.916   2.012   1.907   1.986   2.056   2.120   2.126   2.283
195   K        -0.728  -0.751  -0.800  -0.430  -0.446  -0.549  -0.621  -0.648  -0.684
196   S        -0.728  -0.781  -0.835  -0.811  -0.811  -1.000  -0.621  -0.683  -0.723
197   L         1.912   1.916   2.012   1.790   1.757   1.939   2.120   2.126   2.283
198   A        -0.237  -0.185  -0.229  -0.160  -0.098  -0.135  -0.393  -0.336  -0.365
199   S        -0.728  -0.682  -0.828  -0.669  -0.521  -0.799  -0.621  -0.568  -0.715
200   L        -0.237  -0.274  -0.267  -0.060  -0.137  -0.107  -0.393  -0.439  -0.415
201   L         0.069   0.130  -0.090   0.225   0.255   0.044   0.064   0.147  -0.155
202   G         0.955   0.940   0.783   1.201   1.171   0.895   0.978   0.954   0.669
203   E        -0.237  -0.263  -0.256  -0.295  -0.334  -0.359  -0.393  -0.428  -0.402
204   H        -0.728  -0.710  -0.807  -0.604  -0.519  -0.689  -0.621  -0.602  -0.692
205   E        -0.422  -0.415  -0.337  -0.849  -0.787  -0.707  -0.621  -0.612  -0.501
206   L        -0.237  -0.216  -0.228  -0.108  -0.131  -0.063  -0.393  -0.356  -0.359
207   T         0.069   0.017  -0.144   0.274   0.282  -0.021   0.064  -0.008  -0.233
208   R         1.912   1.916   2.012   2.016   2.003   2.167   2.120   2.126   2.283
209   T         0.560   0.536   0.561   0.594   0.605   0.568   0.293   0.247   0.256
210   E         0.955   0.912   0.760   1.132   1.109   0.820   0.978   0.909   0.629
211   V         0.955   0.936   0.775   1.190   1.170   0.941   0.978   0.947   0.654
212   V         1.912   1.916   2.012   2.030   2.041   2.181   2.120   2.126   2.283
213   R         0.955   0.912   0.760   0.666   0.567   0.413   0.978   0.909   0.629
214   R        -1.404  -1.380  -1.383  -1.518  -1.524  -1.452  -1.078  -1.056  -1.020
215   L         0.955   0.940   0.783   0.962   0.899   0.737   0.978   0.954   0.669
216   W         1.912   1.916   2.012   2.255   2.276   2.408   2.120   2.126   2.283
217   A        -0.913  -0.907  -0.887  -0.921  -0.874  -0.863  -0.849  -0.843  -0.788
218   Y         0.955   0.942   0.796   1.417   1.401   1.221   0.978   0.957   0.693
219   I         1.912   1.916   2.012   2.025   2.029   2.176   2.120   2.126   2.283
220   K         1.912   1.916   2.012   1.498   1.470   1.643   2.120   2.126   2.283
221   A        -0.237  -0.216  -0.228  -0.271  -0.215  -0.264  -0.393  -0.356  -0.359
222   H         0.560   0.566   0.588   0.742   0.757   0.764   0.293   0.303   0.307
223   N        -0.237  -0.255  -0.250  -0.206  -0.198  -0.244  -0.393  -0.417  -0.394
224   L         1.912   1.916   2.012   1.790   1.757   1.939   2.120   2.126   2.283
225   Q         1.912   1.916   2.012   2.021   2.055   2.171   2.120   2.126   2.283
226   N         0.560   0.547   0.573   0.564   0.563   0.558   0.293   0.267   0.279
227   P         1.912   1.916   2.012   2.025   2.090   2.176   2.120   2.126   2.283
228   N        -1.404  -1.367  -1.373  -1.141  -1.024  -1.101  -1.078  -1.043  -1.011
229   N         0.955   0.912   0.760   1.116   1.093   0.850   0.978   0.909   0.629
230   K         0.955   0.940   0.783   0.666   0.603   0.445   0.978   0.954   0.669
231   K         0.955   0.912   0.760   1.084   0.987   0.735   0.978   0.909   0.629
232   E        -0.237  -0.263  -0.266  -0.248  -0.245  -0.309  -0.393  -0.429  -0.415
233   I         1.912   1.916   2.012   2.025   2.029   2.176   2.120   2.126   2.283
234   L        -0.237  -0.193  -0.253  -0.283  -0.256  -0.342  -0.393  -0.350  -0.398
235   C         1.912   1.916   2.012   2.237   2.256   2.390   2.120   2.126   2.283
236   D         1.912   1.916   2.012   1.950   1.991   2.100   2.120   2.126   2.283
237   E        -0.237  -0.227  -0.241  -0.372  -0.290  -0.358  -0.393  -0.385  -0.381
238   K         0.955   0.940   0.783   0.648   0.588   0.414   0.978   0.954   0.669
239   L         0.955   0.940   0.783   0.988   0.925   0.782   0.978   0.954   0.669
240   E        -0.237  -0.274  -0.267  -0.450  -0.519  -0.563  -0.393  -0.439  -0.415
241   L        -1.404  -1.401  -1.382  -1.360  -1.345  -1.352  -1.078  -1.075  -1.019
242   I        -0.422  -0.415  -0.337  -0.472  -0.490  -0.333  -0.621  -0.612  -0.501
243   L         0.955   0.912   0.760   1.277   1.210   0.971   0.978   0.909   0.629
244   G        -0.237  -0.263  -0.266  -0.536  -0.581  -0.541  -0.393  -0.429  -0.415
245   -        -0.297  -0.306  -0.300  -0.591  -0.640  -0.560  -0.450  -0.463  -0.452
246   K        -0.728  -0.763  -0.824  -0.996  -1.037  -1.134  -0.621  -0.662  -0.711
247   S         0.069   0.037  -0.131   0.148   0.157  -0.197   0.064   0.021  -0.213
248   T        -1.404  -1.442  -1.402  -0.990  -1.083  -0.982  -1.078  -1.112  -1.037
249   N        -0.913  -0.924  -0.897  -0.524  -0.537  -0.480  -0.849  -0.857  -0.796
250   M         0.560   0.612   0.602   0.689   0.767   0.733   0.293   0.387   0.334
251   F         1.912   1.916   2.012   2.155   2.168   2.307   2.120   2.126   2.283
252   E        -0.913  -0.880  -0.888  -0.790  -0.706  -0.724  -0.849  -0.818  -0.789
253   M         0.955   0.940   0.783   1.277   1.241   1.010   0.978   0.954   0.669
254   H         0.955   0.912   0.760   1.210   1.174   0.969   0.978   0.909   0.629
255   K         1.912   1.916   2.012   1.498   1.470   1.643   2.120   2.126   2.283
256   I        -0.728  -0.735  -0.803  -0.304  -0.347  -0.396  -0.621  -0.629  -0.687
257   L         1.912   1.916   2.012   1.790   1.757   1.939   2.120   2.126   2.283
258   A        -0.728  -0.781  -0.835  -0.447  -0.473  -0.583  -0.621  -0.683  -0.723
259   S        -1.404  -1.380  -1.383  -1.164  -1.120  -1.144  -1.078  -1.056  -1.020
260   H         0.069   0.039  -0.122   0.488   0.435   0.187   0.064   0.022  -0.201
261   M        -0.422  -0.415  -0.336  -0.394  -0.431  -0.261  -0.621  -0.612  -0.500
262   T        -0.237  -0.260  -0.256   0.066   0.029   0.055  -0.393  -0.426  -0.402
263   E        -0.107  -0.109  -0.197  -0.421  -0.428  -0.556  -0.182  -0.186  -0.307
264   P         0.482   0.488   0.544   0.481   0.532   0.565   0.146   0.156   0.222
265   K        -0.107  -0.138  -0.227  -0.282  -0.268  -0.508  -0.182  -0.226  -0.351
266   K        -0.329  -0.339  -0.284  -0.645  -0.609  -0.597  -0.511  -0.520  -0.438
267   I        -1.033  -1.028  -0.955  -0.691  -0.684  -0.570  -0.964  -0.958  -0.854
268   S        -1.033  -1.028  -0.955  -0.915  -0.920  -0.796  -0.964  -0.958  -0.854
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   D        -0.297  -0.312  -0.268  -0.467  -0.502  -0.460  -0.450  -0.471  -0.408
276   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   V        -0.297  -0.313  -0.267  -0.201  -0.223  -0.162  -0.450  -0.472  -0.406
284   R        -0.297  -0.273  -0.266  -0.413  -0.382  -0.360  -0.450  -0.418  -0.404
285   R         0.717   0.694   0.664   0.566   0.535   0.484   0.578   0.536   0.452
286   K        -0.297  -0.312  -0.268  -0.605  -0.621  -0.546  -0.450  -0.471  -0.408
287   E        -0.297  -0.325  -0.300  -0.287  -0.342  -0.329  -0.450  -0.489  -0.452
288   K        -0.297  -0.312  -0.268  -0.620  -0.638  -0.564  -0.450  -0.471  -0.408
289   P         1.912   1.916   2.012   2.017   2.036   2.168   2.120   2.126   2.283
290   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   D        -0.107  -0.090  -0.160  -0.100  -0.067  -0.220  -0.182  -0.159  -0.255
294   -         0.440   0.445   0.531   0.222   0.223   0.351   0.064   0.072   0.197
295   -        -0.297  -0.326  -0.300  -0.185  -0.233  -0.200  -0.450  -0.490  -0.452
296   -         0.717   0.791   0.678   0.315   0.419   0.260   0.578   0.705   0.478
297   -        -1.033  -1.026  -0.955  -0.997  -0.984  -0.879  -0.964  -0.955  -0.854
298   -         0.717   0.791   0.678   0.617   0.723   0.569   0.578   0.705   0.478
299   -        -1.033  -1.026  -0.955  -1.318  -1.323  -1.203  -0.964  -0.955  -0.854
300   -        -0.297  -0.250  -0.267  -0.685  -0.628  -0.627  -0.450  -0.384  -0.406
301   -        -0.297  -0.256  -0.278  -0.426  -0.367  -0.391  -0.450  -0.393  -0.421
302   -        -1.033  -1.026  -0.955  -0.882  -0.884  -0.762  -0.964  -0.955  -0.854
303   S        -1.507  -1.501  -1.433  -1.489  -1.456  -1.376  -1.169  -1.163  -1.063
304   E         0.849   0.870   0.756   0.732   0.768   0.591   0.804   0.839   0.620
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   Q        -0.918  -0.887  -0.895  -0.746  -0.681  -0.727  -0.840  -0.806  -0.790
307   S        -0.918  -0.923  -0.890  -0.666  -0.671  -0.608  -0.840  -0.844  -0.784
308   D        -1.507  -1.501  -1.433  -1.344  -1.335  -1.230  -1.169  -1.163  -1.063
309   T        -0.918  -0.953  -0.920  -0.878  -0.938  -0.896  -0.840  -0.878  -0.817
310   K        -0.918  -0.953  -0.920  -1.254  -1.335  -1.298  -0.840  -0.878  -0.817
311   G        -0.107  -0.165  -0.208  -0.106  -0.186  -0.230  -0.182  -0.265  -0.324
312   I        -1.507  -1.501  -1.433  -1.215  -1.194  -1.099  -1.169  -1.163  -1.063
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08747
Output conservation file - output/Q08747
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
