1     M         1.311   1.409   1.505   1.563   1.697   1.838   1.410   1.545   1.693
2     S         1.311   1.409   1.505   1.335   1.453   1.627   1.410   1.545   1.693
3     A        -2.041  -1.818  -1.665  -2.068  -1.727  -1.531  -1.761  -1.489  -1.268
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     E        -1.463  -1.138  -1.182  -1.698  -1.145  -1.303  -1.443  -1.028  -1.038
9     D        -1.761  -1.621  -1.620  -1.749  -1.578  -1.617  -1.502  -1.338  -1.230
10    Y        -1.092  -1.173  -1.177  -0.582  -0.797  -0.766  -1.016  -1.105  -1.034
11    K        -0.347  -0.476  -0.575  -0.570  -0.759  -0.866  -0.369  -0.574  -0.663
12    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    P         0.457   0.510   0.264   0.510   0.563   0.201   0.440   0.514   0.071
15    V         0.526   0.368   0.292   0.671   0.486   0.339   0.543   0.290   0.122
16    T         0.526   0.368   0.292   0.626   0.437   0.305   0.543   0.290   0.122
17    V         0.526   0.368   0.292   0.682   0.506   0.369   0.543   0.290   0.122
18    E        -0.067   0.020   0.145  -0.351  -0.231  -0.044  -0.448  -0.319  -0.146
19    K         0.526   0.368   0.292   0.261   0.096  -0.026   0.543   0.290   0.122
20    P        -0.221  -0.237  -0.510  -0.053  -0.117  -0.465  -0.200  -0.235  -0.574
21    I        -0.221  -0.369  -0.537   0.102  -0.108  -0.403  -0.200  -0.396  -0.612
22    P         1.311   1.409   1.505   1.276   1.391   1.572   1.410   1.545   1.693
23    V        -1.215  -1.343  -1.177  -1.086  -1.221  -1.033  -1.191  -1.259  -1.034
24    V        -0.221  -0.225  -0.508  -0.051  -0.066  -0.479  -0.200  -0.221  -0.571
25    Y         0.140   0.003   0.147   0.427   0.179   0.374  -0.076  -0.349  -0.143
26    D         1.311   1.409   1.505   1.284   1.446   1.579   1.410   1.545   1.693
27    L         1.311   1.409   1.505   1.110   1.247   1.418   1.410   1.545   1.693
28    G         1.311   1.409   1.505   1.383   1.516   1.671   1.410   1.545   1.693
29    N         0.526   0.348   0.278   0.635   0.399   0.214   0.543   0.256   0.098
30    L         0.526   0.368   0.292   0.472   0.299   0.219   0.543   0.290   0.122
31    A        -0.221  -0.281  -0.527  -0.003  -0.135  -0.516  -0.200  -0.291  -0.598
32    A        -0.943  -0.714  -0.620  -1.093  -0.722  -0.612  -1.191  -0.871  -0.726
33    F         0.526   0.348   0.278   0.900   0.657   0.505   0.543   0.256   0.098
34    D         1.311   1.409   1.505   1.284   1.446   1.579   1.410   1.545   1.693
35    S        -1.303  -1.239  -1.168  -1.312  -1.215  -1.063  -1.315  -1.195  -1.028
36    N         0.526   0.368   0.292   0.667   0.482   0.327   0.543   0.290   0.122
37    V        -0.067   0.161   0.192  -0.295   0.065   0.097  -0.448  -0.062  -0.059
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    L        -0.221  -0.022  -0.498  -0.205   0.061  -0.552  -0.200   0.078  -0.558
41    D         1.311   1.409   1.505   1.284   1.446   1.579   1.410   1.545   1.693
42    K        -1.916  -1.847  -1.656  -2.011  -1.926  -1.722  -1.663  -1.528  -1.260
43    N        -1.092  -1.071  -1.169  -0.931  -0.938  -1.119  -1.016  -0.998  -1.024
44    D        -0.111  -0.033   0.140  -0.652  -0.566  -0.289  -0.531  -0.416  -0.156
45    L        -0.347  -0.061  -0.541  -0.343   0.024  -0.567  -0.369   0.030  -0.617
46    D        -0.668  -0.692  -0.634  -0.798  -0.865  -0.835  -0.809  -0.824  -0.742
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    S        -0.795  -0.777  -0.642  -1.083  -1.027  -0.870  -1.012  -0.942  -0.752
49    S        -0.718  -0.752  -0.606  -0.818  -0.827  -0.621  -0.943  -0.912  -0.710
50    N        -1.440  -1.418  -1.200  -1.459  -1.394  -1.097  -1.438  -1.344  -1.059
51    A        -0.718  -0.525  -0.583  -0.759  -0.459  -0.521  -0.943  -0.636  -0.678
52    R        -2.161  -1.858  -1.952  -1.895  -1.501  -1.657  -1.686  -1.370  -1.339
53    R        -0.718  -0.794  -0.612  -1.071  -1.225  -0.944  -0.943  -0.975  -0.718
54    E         1.311   1.409   1.505   1.246   1.363   1.544   1.410   1.545   1.693
55    E        -1.215  -1.238  -1.168  -1.204  -1.297  -1.141  -1.191  -1.190  -1.028
56    K        -3.019  -2.785  -2.591  -2.390  -2.020  -1.830  -2.058  -1.819  -1.545
57    I        -0.067   0.161   0.192  -0.383  -0.036   0.019  -0.448  -0.062  -0.059
58    K        -1.801  -1.821  -1.640  -1.866  -1.769  -1.497  -1.562  -1.513  -1.248
59    S        -0.221   0.003  -0.493  -0.002   0.279  -0.408  -0.200   0.110  -0.551
60    L        -0.718  -0.795  -0.608  -0.901  -0.973  -0.700  -0.943  -0.976  -0.714
61    T        -0.564  -0.768  -0.614  -0.543  -0.856  -0.628  -0.695  -0.936  -0.721
62    R         1.311   1.409   1.505   1.350   1.459   1.641   1.410   1.545   1.693
63    D         1.311   1.409   1.505   1.284   1.446   1.579   1.410   1.545   1.693
64    N         0.526   0.348   0.278   0.673   0.467   0.321   0.543   0.256   0.098
65    V        -0.221  -0.369  -0.537   0.063  -0.087  -0.334  -0.200  -0.396  -0.612
66    Q         1.311   1.409   1.505   1.387   1.529   1.675   1.410   1.545   1.693
67    L        -0.221  -0.584  -0.561  -0.216  -0.707  -0.669  -0.200  -0.674  -0.644
68    L         1.311   1.409   1.505   1.110   1.247   1.418   1.410   1.545   1.693
69    I         0.526   0.368   0.292   0.772   0.572   0.420   0.543   0.290   0.122
70    N         1.311   1.409   1.505   1.339   1.497   1.631   1.410   1.545   1.693
71    Q         0.526   0.368   0.292   0.659   0.429   0.219   0.543   0.290   0.122
72    L        -0.718  -0.704  -0.582  -0.856  -0.776  -0.576  -0.943  -0.844  -0.677
73    L         0.526   0.368   0.292   0.453   0.268   0.171   0.543   0.290   0.122
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    S         0.526   0.348   0.278   0.668   0.419   0.312   0.543   0.256   0.098
76    L        -0.221  -0.369  -0.537  -0.159  -0.311  -0.502  -0.200  -0.396  -0.612
77    P         1.311   1.409   1.505   1.276   1.391   1.572   1.410   1.545   1.693
78    M        -1.215  -1.062  -1.128  -1.033  -0.849  -0.945  -1.191  -0.969  -0.982
79    K        -0.925  -1.126  -1.149  -1.063  -1.366  -1.336  -0.819  -1.044  -1.004
80    T        -2.658  -2.525  -2.319  -2.431  -2.232  -1.972  -1.934  -1.755  -1.474
81    T         1.311   1.409   1.505   1.291   1.432   1.586   1.410   1.545   1.693
82    T        -0.221  -0.584  -0.561  -0.053  -0.578  -0.573  -0.200  -0.674  -0.644
83    E        -0.718  -0.794  -0.606  -0.888  -0.955  -0.676  -0.943  -0.975  -0.711
84    S        -1.215  -1.053  -1.167  -1.017  -0.872  -0.916  -1.191  -1.028  -1.028
85    V        -2.420  -2.293  -2.024  -2.090  -1.915  -1.551  -1.893  -1.707  -1.391
86    G         0.373   0.300   0.204   0.525   0.424   0.222   0.309   0.177  -0.038
87    G        -0.132  -0.030   0.140  -0.314  -0.160   0.098  -0.571  -0.411  -0.156
88    T        -0.496  -0.356  -0.600  -0.368  -0.163  -0.598  -0.571  -0.363  -0.696
89    G        -0.977  -0.866  -0.653  -1.132  -0.949  -0.647  -1.232  -1.058  -0.766
90    G         0.373   0.300   0.204   0.513   0.405   0.193   0.309   0.177  -0.038
91    Q         1.311   1.409   1.505   1.377   1.512   1.665   1.410   1.545   1.693
92    S        -0.795  -0.670  -0.635  -0.871  -0.680  -0.625  -1.012  -0.813  -0.744
93    S         0.373   0.472   0.218   0.499   0.641   0.232   0.309   0.455  -0.012
94    V        -0.496  -0.318  -0.593  -0.420  -0.156  -0.602  -0.571  -0.312  -0.687
95    M         0.373   0.472   0.218   0.685   0.822   0.368   0.309   0.455  -0.012
96    T        -1.215  -1.138  -1.176  -1.129  -1.046  -1.064  -1.191  -1.096  -1.036
97    L         1.311   1.409   1.505   1.110   1.247   1.418   1.410   1.545   1.693
98    L        -0.718  -0.447  -0.578  -0.904  -0.536  -0.656  -0.943  -0.565  -0.673
99    Q        -0.221  -0.369  -0.537   0.089  -0.113  -0.345  -0.200  -0.396  -0.612
100   L         1.311   1.409   1.505   1.110   1.247   1.418   1.410   1.545   1.693
101   P         1.311   1.409   1.505   1.276   1.391   1.572   1.410   1.545   1.693
102   D        -1.215  -1.180  -1.153  -1.204  -1.146  -1.104  -1.191  -1.087  -1.010
103   P         0.526   0.368   0.292   0.597   0.373   0.255   0.543   0.290   0.122
104   T        -1.215  -1.403  -1.186  -1.125  -1.364  -1.073  -1.191  -1.323  -1.045
105   T         0.526   0.729   0.316   0.619   0.884   0.325   0.543   0.834   0.164
106   D        -2.298  -1.916  -1.990  -2.116  -1.603  -1.658  -1.810  -1.419  -1.368
107   L         1.311   1.409   1.505   1.110   1.247   1.418   1.410   1.545   1.693
108   P         1.311   1.409   1.505   1.276   1.391   1.572   1.410   1.545   1.693
109   R         1.311   1.409   1.505   1.350   1.459   1.641   1.410   1.545   1.693
110   E         0.526   0.368   0.292   0.579   0.361   0.259   0.543   0.290   0.122
111   K         1.311   1.409   1.505   0.934   1.096   1.254   1.410   1.545   1.693
112   P         0.526   0.787   0.321   0.608   0.910   0.332   0.543   0.911   0.173
113   L        -0.718  -0.752  -0.606  -0.904  -0.915  -0.688  -0.943  -0.912  -0.710
114   P         1.311   1.409   1.505   1.276   1.391   1.572   1.410   1.545   1.693
115   K         0.526   0.348   0.278   0.253   0.049  -0.069   0.543   0.256   0.098
116   A        -0.564  -0.168  -0.540  -0.559  -0.019  -0.531  -0.695  -0.140  -0.620
117   K         1.311   1.409   1.505   0.934   1.096   1.254   1.410   1.545   1.693
118   A         0.140   0.152   0.175   0.131   0.113   0.105  -0.076  -0.078  -0.090
119   M        -1.576  -1.349  -1.220  -1.706  -1.377  -1.185  -1.562  -1.266  -1.077
120   T         1.311   1.409   1.505   1.291   1.432   1.586   1.410   1.545   1.693
121   K         1.311   1.409   1.505   0.934   1.096   1.254   1.410   1.545   1.693
122   W         1.311   1.409   1.505   1.559   1.695   1.835   1.410   1.545   1.693
123   E        -0.718  -0.717  -0.587  -0.802  -0.738  -0.575  -0.943  -0.862  -0.684
124   K        -1.215  -1.191  -1.151  -1.246  -1.147  -1.185  -1.191  -1.099  -1.007
125   F         1.311   1.409   1.505   1.574   1.698   1.848   1.410   1.545   1.693
126   A         1.311   1.409   1.505   1.368   1.499   1.658   1.410   1.545   1.693
127   A        -0.925  -1.217  -1.168  -0.730  -1.259  -1.269  -0.819  -1.131  -1.024
128   K        -0.718  -0.785  -0.607  -1.087  -1.101  -0.803  -0.943  -0.964  -0.713
129   K         0.526   0.348   0.278   0.262   0.056  -0.043   0.543   0.256   0.098
130   G         1.311   1.409   1.505   1.383   1.516   1.671   1.410   1.545   1.693
131   I         1.311   1.409   1.505   1.445   1.580   1.729   1.410   1.545   1.693
132   K         0.526   0.368   0.292   0.265   0.097  -0.014   0.543   0.290   0.122
133   P        -0.221   0.031  -0.488  -0.053   0.248  -0.430  -0.200   0.144  -0.545
134   K         1.311   1.409   1.505   0.934   1.096   1.254   1.410   1.545   1.693
135   E        -1.303  -1.438  -1.194  -1.410  -1.649  -1.295  -1.315  -1.363  -1.053
136   R         0.140   0.425   0.256   0.007   0.451   0.108  -0.076   0.382   0.058
137   A        -1.440  -1.230  -1.196  -1.509  -1.244  -1.150  -1.438  -1.181  -1.056
138   G         0.526   0.348   0.278   0.718   0.489   0.360   0.543   0.256   0.098
139   K         0.140   0.003   0.147  -0.268  -0.482  -0.229  -0.076  -0.349  -0.143
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   M        -0.067  -0.029   0.145  -0.159  -0.230   0.037  -0.448  -0.409  -0.147
143   I        -0.564  -0.553  -0.566  -0.453  -0.394  -0.453  -0.695  -0.632  -0.653
144   Y        -0.067   0.019   0.149   0.089   0.207   0.376  -0.448  -0.320  -0.140
145   D         1.311   1.409   1.505   1.284   1.446   1.579   1.410   1.545   1.693
146   E         1.311   1.409   1.505   1.246   1.363   1.544   1.410   1.545   1.693
147   A        -0.221  -0.246  -0.526   0.018  -0.042  -0.466  -0.200  -0.252  -0.596
148   S        -0.564  -0.427  -0.572  -0.543  -0.391  -0.562  -0.695  -0.533  -0.665
149   G         1.311   1.409   1.505   1.383   1.516   1.671   1.410   1.545   1.693
150   E         0.140   0.300   0.196  -0.097   0.146  -0.125  -0.076   0.176  -0.052
151   W         0.526   0.348   0.278   0.919   0.705   0.581   0.543   0.256   0.098
152   V        -0.221  -0.281  -0.527   0.018  -0.060  -0.424  -0.200  -0.291  -0.598
153   P         0.526   0.348   0.278   0.606   0.349   0.254   0.543   0.256   0.098
154   K         1.311   1.409   1.505   0.934   1.096   1.254   1.410   1.545   1.693
155   W         1.311   1.409   1.505   1.559   1.695   1.835   1.410   1.545   1.693
156   G         1.311   1.409   1.505   1.383   1.516   1.671   1.410   1.545   1.693
157   Y         0.526   0.628   0.306   0.939   1.085   0.644   0.543   0.691   0.147
158   K         0.140   0.300   0.196  -0.271  -0.003  -0.177  -0.076   0.176  -0.052
159   G         1.311   1.409   1.505   1.383   1.516   1.671   1.410   1.545   1.693
160   A        -1.215  -1.005  -1.152  -1.423  -1.145  -1.225  -1.191  -0.950  -1.013
161   N         1.311   1.409   1.505   1.339   1.497   1.631   1.410   1.545   1.693
162   K         1.311   1.409   1.505   0.934   1.096   1.254   1.410   1.545   1.693
163   K        -1.215  -1.103  -1.150  -1.355  -1.155  -1.248  -1.191  -1.019  -1.006
164   L        -0.221  -0.246  -0.526  -0.197  -0.246  -0.575  -0.200  -0.252  -0.596
165   D         0.140   0.003   0.147   0.039  -0.239  -0.037  -0.076  -0.349  -0.143
166   D        -0.221  -0.351  -0.529  -0.050  -0.201  -0.499  -0.200  -0.369  -0.600
167   Q         0.526   0.348   0.278   0.719   0.494   0.356   0.543   0.256   0.098
168   W         0.526   0.348   0.278   0.878   0.629   0.469   0.543   0.256   0.098
169   L        -0.221  -0.369  -0.537  -0.149  -0.327  -0.479  -0.200  -0.396  -0.612
170   V         0.526   0.348   0.278   0.682   0.476   0.346   0.543   0.256   0.098
171   E         1.311   1.409   1.505   1.246   1.363   1.544   1.410   1.545   1.693
172   V         0.526   0.368   0.292   0.654   0.453   0.293   0.543   0.290   0.122
173   D         0.457   0.194   0.235   0.513   0.158   0.185   0.440  -0.006   0.020
174   D         0.457   0.194   0.235   0.492   0.107   0.128   0.440  -0.006   0.020
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   K        -0.221  -0.022  -0.498  -0.412  -0.117  -0.766  -0.200   0.078  -0.558
179   V        -0.679  -0.624  -0.619  -0.880  -0.921  -0.899  -0.855  -0.803  -0.726
180   K        -0.347  -0.476  -0.575  -0.547  -0.720  -0.817  -0.369  -0.574  -0.663
181   G        -0.679  -0.810  -0.625  -0.635  -0.819  -0.581  -0.855  -0.983  -0.733
182   T        -0.347  -0.602  -0.595  -0.227  -0.643  -0.627  -0.369  -0.719  -0.690
183   D         0.457   0.676   0.282   0.491   0.771   0.215   0.440   0.759   0.104
184   N        -0.679  -0.765  -0.617  -0.844  -1.018  -0.839  -0.855  -0.923  -0.721
185   E        -0.347  -0.602  -0.595  -0.235  -0.646  -0.619  -0.369  -0.719  -0.690
186   L         0.065  -0.014   0.140  -0.126  -0.218   0.044  -0.207  -0.381  -0.156
187   I        -0.347  -0.602  -0.595  -0.094  -0.508  -0.573  -0.369  -0.719  -0.690
188   D         0.457   0.181   0.235   0.495   0.090   0.131   0.440  -0.027   0.020
189   P         0.457   0.181   0.235   0.528   0.105   0.197   0.440  -0.027   0.020
190   R         0.457   0.181   0.235   0.534   0.021   0.068   0.440  -0.027   0.020
191   T        -0.679  -0.705  -0.619  -0.724  -0.792  -0.634  -0.855  -0.880  -0.727
192   L         0.457   0.181   0.235   0.354  -0.034   0.034   0.440  -0.027   0.020
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   N        -0.679  -0.703  -0.620  -0.891  -0.994  -0.908  -0.855  -0.876  -0.728
197   R         1.311   1.409   1.505   1.357   1.453   1.647   1.410   1.545   1.693
198   A         0.457   0.181   0.235   0.605   0.171   0.254   0.440  -0.027   0.020
199   E         0.457   0.510   0.264   0.506   0.573   0.218   0.440   0.514   0.071
200   R        -0.221  -0.584  -0.561   0.019  -0.519  -0.493  -0.200  -0.674  -0.644
201   K         0.526   0.348   0.278   0.262   0.056  -0.043   0.543   0.256   0.098
202   R        -0.718  -0.793  -0.605  -1.042  -1.202  -0.898  -0.943  -0.973  -0.709
203   L         0.526   0.348   0.278   0.439   0.207   0.110   0.543   0.256   0.098
204   V        -0.564  -0.537  -0.562  -0.471  -0.400  -0.481  -0.695  -0.610  -0.649
205   K         0.526   0.368   0.292   0.260   0.085  -0.028   0.543   0.290   0.122
206   K         0.526   0.348   0.278   0.262   0.056  -0.043   0.543   0.256   0.098
207   N         0.526   0.368   0.292   0.674   0.500   0.346   0.543   0.290   0.122
208   E        -0.564  -0.609  -0.583  -0.571  -0.623  -0.594  -0.695  -0.709  -0.678
209   K        -0.943  -0.734  -0.636  -1.429  -1.015  -0.950  -1.191  -0.884  -0.744
210   Q        -0.221  -0.584  -0.561  -0.012  -0.566  -0.634  -0.200  -0.674  -0.644
211   Q        -1.303  -1.438  -1.194  -0.975  -1.110  -0.802  -1.315  -1.363  -1.053
212   R        -1.215  -1.316  -1.177  -1.483  -1.589  -1.327  -1.191  -1.253  -1.037
213   R        -0.564  -0.747  -0.607  -0.635  -0.978  -0.811  -0.695  -0.905  -0.711
214   N         0.526   0.368   0.292   0.611   0.397   0.176   0.543   0.290   0.122
215   M        -0.925  -1.116  -1.151  -0.816  -1.117  -1.065  -0.819  -1.035  -1.006
216   K         0.140   0.139   0.162  -0.268  -0.266  -0.216  -0.076  -0.102  -0.115
217   N        -0.067  -0.029   0.145  -0.234  -0.209   0.064  -0.448  -0.409  -0.147
218   A        -1.801  -1.877  -1.644  -1.582  -1.723  -1.378  -1.562  -1.548  -1.251
219   L        -2.298  -2.097  -1.988  -2.033  -1.780  -1.597  -1.810  -1.583  -1.367
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -2.041  -1.910  -1.665  -2.140  -1.998  -1.598  -1.761  -1.571  -1.268
223   -        -1.276  -1.127  -1.135  -1.396  -1.148  -1.123  -1.232  -1.029  -0.989
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08746
Output conservation file - output/Q08746
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
