1     M         1.808   1.831   1.909   1.989   2.021   2.144   2.001   2.034   2.155
2     P         0.010   0.018  -0.039   0.177   0.187   0.083  -0.140  -0.130  -0.226
3     L         0.535   0.557   0.622   0.097   0.131   0.215   0.166   0.199   0.276
4     Q        -0.713  -0.696  -0.684  -0.631  -0.607  -0.599  -0.752  -0.729  -0.700
5     L         1.808   1.831   1.909   1.595   1.628   1.753   2.001   2.034   2.155
6     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    H        -0.713  -0.691  -0.666  -0.661  -0.632  -0.613  -0.752  -0.724  -0.680
19    Y        -0.713  -0.693  -0.648  -0.680  -0.651  -0.595  -0.752  -0.726  -0.660
20    D         0.010   0.013  -0.062   0.045   0.048  -0.085  -0.140  -0.137  -0.258
21    N        -0.713  -0.707  -0.652  -0.871  -0.868  -0.795  -0.752  -0.742  -0.664
22    G         0.010   0.021  -0.067   0.150   0.166   0.002  -0.140  -0.126  -0.267
23    N         0.010   0.039  -0.057  -0.176  -0.133  -0.314  -0.140  -0.099  -0.251
24    M        -1.237  -1.226  -1.122  -1.033  -1.017  -0.857  -1.058  -1.041  -0.910
25    S        -0.188  -0.178  -0.135  -0.379  -0.363  -0.275  -0.446  -0.432  -0.367
26    N         0.010   0.039  -0.057  -0.025   0.019  -0.176  -0.140  -0.099  -0.251
27    D        -0.159  -0.152  -0.105  -0.248  -0.237  -0.172  -0.389  -0.380  -0.321
28    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    S        -0.708  -0.669  -0.642  -0.789  -0.734  -0.672  -0.761  -0.715  -0.659
47    W        -0.543  -0.468  -0.588  -0.333  -0.207  -0.442  -0.548  -0.452  -0.589
48    T        -1.145  -1.155  -1.078  -1.010  -1.038  -0.902  -0.973  -0.979  -0.871
49    R        -1.145  -1.141  -1.074  -1.243  -1.280  -1.151  -0.973  -0.966  -0.868
50    R        -0.708  -0.737  -0.671  -0.757  -0.808  -0.705  -0.761  -0.785  -0.687
51    A        -1.145  -1.071  -1.068  -0.930  -0.840  -0.809  -0.973  -0.894  -0.862
52    A        -1.145  -1.066  -1.065  -1.125  -1.009  -1.011  -0.973  -0.888  -0.859
53    A        -1.145  -1.133  -1.090  -1.109  -1.105  -1.031  -0.973  -0.959  -0.882
54    A        -1.582  -1.555  -1.465  -1.481  -1.427  -1.302  -1.186  -1.157  -1.038
55    L        -1.582  -1.555  -1.465  -1.678  -1.594  -1.497  -1.186  -1.157  -1.038
56    R         0.167   0.226   0.050   0.337   0.412   0.162   0.089   0.175  -0.093
57    T        -1.145  -1.148  -1.093  -1.268  -1.266  -1.217  -0.973  -0.972  -0.885
58    L        -0.106  -0.057  -0.074  -0.490  -0.414  -0.427  -0.336  -0.266  -0.281
59    M        -0.543  -0.463  -0.600  -0.468  -0.349  -0.567  -0.548  -0.447  -0.604
60    N        -1.145  -1.075  -1.069  -1.087  -0.982  -0.961  -0.973  -0.897  -0.863
61    K        -1.145  -1.084  -1.073  -0.997  -0.900  -0.901  -0.973  -0.906  -0.866
62    R        -0.543  -0.593  -0.612  -0.388  -0.485  -0.501  -0.548  -0.611  -0.618
63    I         0.167   0.233   0.049   0.219   0.318   0.052   0.089   0.185  -0.095
64    Q        -0.543  -0.456  -0.554  -0.642  -0.509  -0.669  -0.548  -0.438  -0.549
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    R        -0.608  -0.542  -0.597  -0.471  -0.374  -0.405  -0.652  -0.569  -0.604
67    I         1.808   1.831   1.909   1.772   1.810   1.928   2.001   2.034   2.155
68    T        -0.000   0.068  -0.042   0.021   0.133  -0.061  -0.184  -0.080  -0.237
69    L         0.301   0.378   0.104   0.192   0.294  -0.089   0.284   0.394  -0.014
70    T        -0.233  -0.175  -0.135  -0.668  -0.581  -0.513  -0.496  -0.414  -0.365
71    H         0.516   0.536   0.621   0.494   0.531   0.654   0.128   0.157   0.274
72    W        -0.233  -0.230  -0.143  -0.297  -0.301  -0.165  -0.496  -0.494  -0.376
73    L        -1.124  -1.066  -1.059  -1.356  -1.250  -1.266  -0.965  -0.908  -0.858
74    L        -0.000  -0.042  -0.052  -0.243  -0.289  -0.346  -0.184  -0.227  -0.252
75    L        -0.608  -0.657  -0.609  -0.885  -0.965  -0.859  -0.652  -0.702  -0.623
76    V        -1.499  -1.478  -1.426  -1.580  -1.549  -1.484  -1.121  -1.097  -1.008
77    I         0.301   0.362   0.081   0.408   0.497   0.105   0.284   0.372  -0.048
78    W        -0.608  -0.678  -0.633  -0.572  -0.658  -0.594  -0.652  -0.716  -0.645
79    V        -1.499  -1.505  -1.423  -1.478  -1.474  -1.361  -1.121  -1.119  -1.006
80    T        -0.608  -0.562  -0.591  -0.680  -0.618  -0.652  -0.652  -0.601  -0.604
81    S        -0.608  -0.612  -0.632  -0.934  -0.934  -0.979  -0.652  -0.652  -0.647
82    L         0.301   0.229   0.045   0.203   0.091  -0.161   0.284   0.175  -0.100
83    W        -0.608  -0.615  -0.601  -0.726  -0.738  -0.692  -0.652  -0.651  -0.612
84    K        -0.092  -0.047  -0.067  -0.025   0.026   0.050  -0.340  -0.281  -0.283
85    F        -0.000   0.068  -0.042  -0.340  -0.227  -0.393  -0.184  -0.080  -0.237
86    T         1.032   1.067   0.853   1.130   1.179   0.874   1.065   1.117   0.724
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    S        -0.608  -0.602  -0.609  -0.642  -0.608  -0.607  -0.652  -0.634  -0.618
89    H        -0.750  -0.711  -0.672  -0.594  -0.556  -0.480  -0.809  -0.763  -0.689
90    Y         0.676   0.612   0.657   0.568   0.432   0.475   0.440   0.307   0.347
91    R        -1.499  -1.504  -1.452  -1.223  -1.238  -1.127  -1.121  -1.119  -1.028
92    Q        -1.499  -1.459  -1.422  -1.260  -1.191  -1.151  -1.121  -1.079  -1.005
93    L         1.032   0.936   0.828   0.859   0.719   0.542   1.065   0.900   0.677
94    Y         1.032   0.992   0.867   1.208   1.166   1.006   1.065   0.995   0.750
95    A        -1.145  -1.145  -1.107  -0.855  -0.882  -0.801  -0.973  -0.970  -0.897
96    N        -1.145  -1.145  -1.107  -0.986  -0.984  -0.954  -0.973  -0.970  -0.897
97    S        -0.106  -0.163  -0.093  -0.264  -0.336  -0.241  -0.336  -0.401  -0.311
98    A        -0.608  -0.630  -0.633  -0.590  -0.617  -0.594  -0.652  -0.666  -0.648
99    V        -0.000  -0.052  -0.052  -0.319  -0.406  -0.397  -0.184  -0.256  -0.257
100   F        -0.608  -0.608  -0.615  -0.847  -0.866  -0.871  -0.652  -0.655  -0.632
101   A         0.516   0.527   0.607   0.356   0.352   0.485   0.128   0.138   0.247
102   T        -1.124  -1.165  -1.093  -1.101  -1.139  -1.021  -0.965  -0.991  -0.886
103   L        -0.608  -0.522  -0.591  -0.583  -0.428  -0.552  -0.652  -0.547  -0.598
104   C        -0.608  -0.597  -0.619  -0.629  -0.620  -0.665  -0.652  -0.628  -0.631
105   T         1.032   1.067   0.853   1.113   1.164   0.843   1.065   1.117   0.724
106   N         1.808   1.831   1.909   1.843   1.883   1.999   2.001   2.034   2.155
107   I        -1.124  -1.132  -1.080  -1.231  -1.231  -1.101  -0.965  -0.964  -0.874
108   L        -0.092  -0.067  -0.080  -0.405  -0.376  -0.340  -0.340  -0.308  -0.300
109   L         1.808   1.831   1.909   1.592   1.624   1.749   2.001   2.034   2.155
110   F        -0.092  -0.143  -0.090  -0.281  -0.337  -0.243  -0.340  -0.391  -0.312
111   G         1.808   1.831   1.909   1.964   1.997   2.119   2.001   2.034   2.155
112   I        -0.608  -0.649  -0.622  -0.851  -0.933  -0.881  -0.652  -0.695  -0.638
113   S         0.676   0.612   0.657   0.559   0.448   0.510   0.440   0.307   0.347
114   D         0.676   0.737   0.718   0.668   0.771   0.721   0.440   0.545   0.467
115   I        -0.000   0.075  -0.043  -0.043   0.076  -0.090  -0.184  -0.075  -0.239
116   L         0.301   0.164   0.064   0.164  -0.042  -0.201   0.284   0.084  -0.073
117   A         1.808   1.831   1.909   1.939   1.960   2.094   2.001   2.034   2.155
118   Q         1.808   1.831   1.909   1.967   2.002   2.122   2.001   2.034   2.155
119   S        -0.000  -0.011  -0.037  -0.018  -0.020  -0.058  -0.184  -0.189  -0.231
120   I         1.032   1.084   0.867   1.020   1.099   0.748   1.065   1.145   0.749
121   A        -1.124  -1.090  -1.069  -1.290  -1.236  -1.161  -0.965  -0.927  -0.865
122   C        -0.983  -1.024  -1.046  -0.682  -0.751  -0.830  -0.809  -0.849  -0.841
123   F        -0.233  -0.226  -0.147  -0.486  -0.483  -0.366  -0.496  -0.489  -0.382
124   Y        -1.499  -1.451  -1.418  -1.417  -1.329  -1.306  -1.121  -1.073  -1.002
125   S        -0.375  -0.387  -0.556  -0.181  -0.195  -0.402  -0.340  -0.358  -0.552
126   Y        -1.124  -1.097  -1.065  -1.043  -1.011  -0.948  -0.965  -0.932  -0.862
127   H        -1.499  -1.492  -1.422  -1.059  -1.072  -0.934  -1.121  -1.109  -1.005
128   V         0.010   0.012  -0.036  -0.099  -0.117  -0.199  -0.140  -0.141  -0.221
129   D         0.744   0.649   0.694   0.753   0.586   0.640   0.567   0.379   0.420
130   P         0.744   0.649   0.694   0.849   0.679   0.753   0.567   0.379   0.420
131   I        -0.159  -0.170  -0.120  -0.318  -0.339  -0.266  -0.389  -0.411  -0.342
132   P         1.808   1.831   1.909   1.945   1.971   2.100   2.001   2.034   2.155
133   Q        -1.499  -1.492  -1.422  -1.250  -1.277  -1.133  -1.121  -1.109  -1.005
134   I         0.010   0.021  -0.042  -0.170  -0.158  -0.297  -0.140  -0.125  -0.230
135   L        -0.713  -0.696  -0.684  -1.036  -1.011  -1.018  -0.752  -0.729  -0.700
136   N        -0.188  -0.162  -0.132  -0.449  -0.411  -0.351  -0.446  -0.413  -0.363
137   D         0.010   0.035  -0.055   0.180   0.220   0.051  -0.140  -0.104  -0.248
138   T        -0.713  -0.705  -0.669  -0.937  -0.932  -0.907  -0.752  -0.740  -0.683
139   F        -1.237  -1.226  -1.122  -1.301  -1.283  -1.123  -1.058  -1.041  -0.910
140   H        -0.159  -0.098  -0.100  -0.060   0.036   0.031  -0.389  -0.301  -0.314
141   H        -0.159  -0.172  -0.120  -0.184  -0.216  -0.119  -0.389  -0.412  -0.342
142   V        -0.159  -0.172  -0.120  -0.514  -0.537  -0.450  -0.389  -0.412  -0.342
143   Q        -0.815  -0.792  -0.702  -0.867  -0.826  -0.692  -0.867  -0.838  -0.719
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   N        -0.159  -0.099  -0.099  -0.147  -0.046  -0.065  -0.389  -0.302  -0.313
153   N         0.744   0.800   0.729   0.797   0.887   0.743   0.567   0.660   0.490
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   R        -0.713  -0.746  -0.671  -0.648  -0.716  -0.600  -0.752  -0.788  -0.686
172   D        -0.713  -0.694  -0.649  -0.695  -0.674  -0.605  -0.752  -0.729  -0.661
173   V        -0.106  -0.098  -0.093  -0.156  -0.165  -0.152  -0.336  -0.332  -0.313
174   E         0.167   0.116   0.016   0.378   0.294   0.140   0.089   0.010  -0.143
175   N        -1.874  -1.850  -1.755  -1.878  -1.812  -1.696  -1.277  -1.251  -1.129
176   G        -1.499  -1.451  -1.418  -1.381  -1.314  -1.267  -1.121  -1.073  -1.002
177   G        -0.608  -0.558  -0.610  -0.557  -0.485  -0.562  -0.652  -0.601  -0.625
178   G        -1.124  -1.056  -1.079  -0.936  -0.842  -0.864  -0.965  -0.896  -0.874
179   Y        -0.608  -0.515  -0.592  -0.619  -0.468  -0.591  -0.652  -0.542  -0.605
180   E        -1.124  -1.130  -1.064  -0.964  -0.971  -0.866  -0.965  -0.962  -0.862
181   S        -0.000  -0.034  -0.050  -0.030  -0.054  -0.110  -0.184  -0.215  -0.248
182   D         0.516   0.536   0.621   0.383   0.417   0.545   0.128   0.157   0.274
183   E        -0.608  -0.579  -0.618  -0.496  -0.438  -0.473  -0.652  -0.614  -0.631
184   L         0.535   0.540   0.617   0.077   0.072   0.203   0.166   0.164   0.266
185   S         0.010  -0.088  -0.067  -0.092  -0.242  -0.212  -0.140  -0.287  -0.267
186   I        -0.713  -0.746  -0.671  -0.727  -0.771  -0.655  -0.752  -0.788  -0.686
187   F         1.808   1.831   1.909   1.716   1.751   1.872   2.001   2.034   2.155
188   N        -0.543  -0.627  -0.617  -0.471  -0.610  -0.602  -0.548  -0.647  -0.624
189   D         0.167   0.090   0.026   0.294   0.178   0.054   0.089  -0.025  -0.129
190   F         0.604   0.643   0.660   0.421   0.494   0.479   0.302   0.367   0.353
191   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   Y        -0.543  -0.576  -0.599  -0.479  -0.528  -0.591  -0.548  -0.589  -0.602
198   T        -1.124  -1.119  -1.062  -0.964  -0.965  -0.873  -0.965  -0.954  -0.860
199   D        -0.608  -0.649  -0.622  -0.493  -0.536  -0.480  -0.652  -0.695  -0.638
200   N        -0.608  -0.537  -0.593  -0.528  -0.404  -0.502  -0.652  -0.562  -0.606
201   D        -0.608  -0.657  -0.622  -0.671  -0.768  -0.718  -0.652  -0.702  -0.638
202   D        -0.375  -0.344  -0.525  -0.183  -0.131  -0.424  -0.340  -0.301  -0.515
203   Y        -0.608  -0.608  -0.599  -0.523  -0.520  -0.506  -0.652  -0.646  -0.613
204   -         0.010   0.037  -0.029   0.121   0.156   0.051  -0.140  -0.106  -0.210
205   -        -0.188  -0.175  -0.114  -0.263  -0.238  -0.145  -0.446  -0.424  -0.338
206   -        -1.237  -1.216  -1.122  -1.099  -1.064  -0.923  -1.058  -1.033  -0.910
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -0.713  -0.693  -0.640  -0.898  -0.870  -0.771  -0.752  -0.725  -0.650
225   -        -0.713  -0.710  -0.651  -0.684  -0.684  -0.605  -0.752  -0.747  -0.663
226   -         0.010  -0.006  -0.027   0.076   0.051   0.011  -0.140  -0.166  -0.208
227   -        -0.713  -0.700  -0.647  -0.647  -0.626  -0.543  -0.752  -0.735  -0.659
228   -        -0.815  -0.802  -0.702  -0.879  -0.852  -0.704  -0.867  -0.848  -0.719
229   -        -0.159  -0.130  -0.100  -0.287  -0.241  -0.218  -0.389  -0.347  -0.314
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -0.713  -0.702  -0.648  -0.588  -0.592  -0.500  -0.752  -0.738  -0.660
235   -        -0.713  -0.655  -0.651  -0.834  -0.725  -0.753  -0.752  -0.683  -0.663
236   A        -1.499  -1.445  -1.416  -1.228  -1.165  -1.086  -1.121  -1.067  -1.000
237   T        -0.983  -1.032  -1.024  -0.912  -0.990  -1.001  -0.809  -0.857  -0.819
238   F        -1.874  -1.850  -1.755  -1.737  -1.671  -1.556  -1.277  -1.251  -1.129
239   K        -1.124  -1.158  -1.091  -1.009  -1.086  -0.984  -0.965  -0.986  -0.885
240   T        -1.499  -1.504  -1.452  -1.597  -1.592  -1.484  -1.121  -1.119  -1.028
241   D        -1.124  -1.056  -1.079  -0.963  -0.869  -0.867  -0.965  -0.896  -0.874
242   T        -1.124  -1.158  -1.091  -1.107  -1.149  -1.055  -0.965  -0.986  -0.885
243   F         1.032   1.084   0.867   1.009   1.082   0.780   1.065   1.145   0.749
244   D        -1.124  -1.113  -1.076  -0.932  -0.911  -0.851  -0.965  -0.946  -0.871
245   F         1.808   1.831   1.909   1.713   1.748   1.870   2.001   2.034   2.155
246   F        -1.499  -1.504  -1.452  -1.287  -1.274  -1.203  -1.121  -1.119  -1.028
247   R         1.808   1.831   1.909   1.906   1.930   2.061   2.001   2.034   2.155
248   W         0.516   0.555   0.617   0.197   0.244   0.359   0.128   0.195   0.267
249   G        -1.124  -1.056  -1.079  -1.113  -1.030  -1.061  -0.965  -0.896  -0.874
250   C        -0.608  -0.674  -0.624  -0.364  -0.457  -0.369  -0.652  -0.711  -0.637
251   F         1.808   1.831   1.909   1.713   1.748   1.870   2.001   2.034   2.155
252   M         1.808   1.831   1.909   1.989   2.021   2.144   2.001   2.034   2.155
253   F        -1.499  -1.504  -1.452  -1.230  -1.245  -1.196  -1.121  -1.119  -1.028
254   W         0.301   0.164   0.064   0.603   0.395   0.212   0.284   0.084  -0.073
255   G         1.808   1.831   1.909   1.964   1.997   2.119   2.001   2.034   2.155
256   F         0.301   0.362   0.081   0.372   0.455   0.087   0.284   0.372  -0.048
257   F        -0.608  -0.678  -0.633  -0.793  -0.877  -0.814  -0.652  -0.716  -0.645
258   I        -0.233  -0.206  -0.146  -0.475  -0.430  -0.373  -0.496  -0.458  -0.380
259   S        -0.000   0.019  -0.064  -0.043  -0.027  -0.117  -0.184  -0.174  -0.274
260   F         0.301   0.244   0.063   0.373   0.292   0.064   0.284   0.196  -0.074
261   F        -0.375  -0.467  -0.536  -0.450  -0.619  -0.745  -0.340  -0.455  -0.527
262   Q         1.808   1.831   1.909   1.967   2.002   2.122   2.001   2.034   2.155
263   A        -1.124  -1.147  -1.089  -0.955  -1.013  -0.907  -0.965  -0.977  -0.883
264   P        -0.375  -0.387  -0.556  -0.114  -0.135  -0.407  -0.340  -0.358  -0.552
265   W         1.808   1.831   1.909   2.031   2.067   2.185   2.001   2.034   2.155
266   Y         1.032   0.936   0.828   1.143   1.008   0.817   1.065   0.900   0.677
267   K        -0.375  -0.479  -0.550  -0.077  -0.230  -0.364  -0.340  -0.470  -0.544
268   F         0.676   0.671   0.668   0.435   0.422   0.386   0.440   0.421   0.370
269   L         1.032   0.992   0.867   0.876   0.820   0.641   1.065   0.995   0.750
270   N        -0.000  -0.041  -0.049   0.029  -0.012  -0.026  -0.184  -0.225  -0.245
271   F        -1.237  -1.212  -1.122  -1.302  -1.253  -1.124  -1.058  -1.029  -0.910
272   F        -0.000  -0.034  -0.050  -0.127  -0.141  -0.182  -0.184  -0.215  -0.248
273   Y         1.032   0.936   0.828   1.143   1.008   0.817   1.065   0.900   0.677
274   T        -0.608  -0.678  -0.633  -0.638  -0.720  -0.646  -0.652  -0.716  -0.645
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   E        -0.000   0.019  -0.064   0.136   0.151   0.046  -0.184  -0.174  -0.274
278   D         0.676   0.612   0.657   0.681   0.575   0.631   0.440   0.307   0.347
279   P         0.676   0.612   0.657   0.683   0.549   0.605   0.440   0.307   0.347
280   T        -0.608  -0.678  -0.633  -0.543  -0.644  -0.566  -0.652  -0.716  -0.645
281   V        -0.608  -0.678  -0.633  -0.747  -0.846  -0.776  -0.652  -0.716  -0.645
282   V        -0.092  -0.143  -0.090  -0.280  -0.338  -0.238  -0.340  -0.391  -0.312
283   Q        -0.233  -0.230  -0.143  -0.310  -0.323  -0.192  -0.496  -0.494  -0.376
284   V         0.301   0.164   0.064   0.409   0.205   0.051   0.284   0.084  -0.073
285   F         0.301   0.322   0.105   0.144   0.171  -0.166   0.284   0.310  -0.012
286   E        -0.608  -0.678  -0.633  -0.433  -0.521  -0.438  -0.652  -0.716  -0.645
287   R         0.676   0.737   0.718   0.700   0.788   0.755   0.440   0.545   0.467
288   V         1.808   1.831   1.909   1.809   1.837   1.965   2.001   2.034   2.155
289   L         0.301   0.257   0.063   0.238   0.169  -0.072   0.284   0.214  -0.074
290   S        -0.000  -0.034  -0.050  -0.121  -0.161  -0.223  -0.184  -0.215  -0.248
291   D         1.808   1.831   1.909   1.886   1.926   2.041   2.001   2.034   2.155
292   Q         1.808   1.831   1.909   1.967   2.002   2.122   2.001   2.034   2.155
293   L         1.032   1.100   0.865   0.859   0.951   0.607   1.065   1.169   0.747
294   L        -0.608  -0.647  -0.610  -0.749  -0.800  -0.724  -0.652  -0.692  -0.625
295   Y         0.516   0.555   0.617   0.194   0.258   0.352   0.128   0.195   0.267
296   S         1.032   0.936   0.828   1.081   0.963   0.797   1.065   0.900   0.677
297   P         1.808   1.831   1.909   1.945   1.971   2.100   2.001   2.034   2.155
298   I        -0.375  -0.479  -0.550  -0.406  -0.592  -0.740  -0.340  -0.470  -0.544
299   S         1.032   0.936   0.828   1.085   0.971   0.806   1.065   0.900   0.677
300   L         1.808   1.831   1.909   1.592   1.624   1.749   2.001   2.034   2.155
301   Y        -0.608  -0.678  -0.633  -0.591  -0.671  -0.582  -0.652  -0.716  -0.645
302   C         0.301   0.279   0.087   0.640   0.610   0.297   0.284   0.250  -0.039
303   F         1.808   1.831   1.909   1.713   1.748   1.870   2.001   2.034   2.155
304   F         1.808   1.831   1.909   1.713   1.748   1.870   2.001   2.034   2.155
305   M        -0.092  -0.110  -0.083  -0.142  -0.174  -0.118  -0.340  -0.353  -0.303
306   F        -0.000  -0.028  -0.040  -0.060  -0.076  -0.131  -0.184  -0.205  -0.238
307   S        -0.608  -0.678  -0.633  -0.583  -0.665  -0.591  -0.652  -0.716  -0.645
308   N         0.516   0.555   0.617   0.275   0.345   0.430   0.128   0.195   0.267
309   Y        -0.106  -0.149  -0.098  -0.265  -0.333  -0.254  -0.336  -0.384  -0.314
310   V        -0.000  -0.041  -0.047  -0.174  -0.243  -0.289  -0.184  -0.225  -0.250
311   M        -0.750  -0.772  -0.672  -0.932  -0.958  -0.781  -0.809  -0.819  -0.690
312   E         1.808   1.831   1.909   1.950   1.986   2.105   2.001   2.034   2.155
313   G        -0.983  -0.888  -1.005  -0.644  -0.501  -0.676  -0.809  -0.701  -0.800
314   G         1.032   1.100   0.865   1.277   1.366   1.053   1.065   1.169   0.747
315   D        -0.608  -0.638  -0.626  -0.566  -0.603  -0.583  -0.652  -0.684  -0.642
316   K        -0.608  -0.542  -0.597  -0.373  -0.276  -0.342  -0.652  -0.569  -0.604
317   D        -1.499  -1.504  -1.452  -1.321  -1.330  -1.241  -1.121  -1.119  -1.028
318   T        -0.608  -0.624  -0.633  -0.587  -0.590  -0.617  -0.652  -0.661  -0.647
319   L        -0.608  -0.509  -0.595  -0.810  -0.650  -0.800  -0.652  -0.537  -0.606
320   G        -1.874  -1.850  -1.755  -1.528  -1.495  -1.349  -1.277  -1.251  -1.129
321   K        -1.499  -1.478  -1.426  -1.176  -1.140  -1.070  -1.121  -1.097  -1.008
322   K         1.808   1.831   1.909   1.987   2.025   2.141   2.001   2.034   2.155
323   I        -0.092  -0.143  -0.090  -0.434  -0.489  -0.381  -0.340  -0.391  -0.312
324   Q        -0.608  -0.537  -0.595  -0.458  -0.369  -0.422  -0.652  -0.574  -0.608
325   R        -0.375  -0.466  -0.547  -0.140  -0.289  -0.407  -0.340  -0.454  -0.540
326   L        -0.092  -0.110  -0.073  -0.435  -0.452  -0.367  -0.340  -0.353  -0.291
327   Y         1.808   1.831   1.909   1.875   1.911   2.030   2.001   2.034   2.155
328   I        -0.608  -0.516  -0.593  -0.730  -0.580  -0.701  -0.652  -0.538  -0.602
329   S        -0.608  -0.604  -0.615  -0.551  -0.538  -0.550  -0.652  -0.641  -0.625
330   T         1.808   1.831   1.909   1.835   1.868   1.990   2.001   2.034   2.155
331   L         1.808   1.831   1.909   1.592   1.624   1.749   2.001   2.034   2.155
332   G        -0.375  -0.387  -0.556  -0.157  -0.170  -0.486  -0.340  -0.358  -0.552
333   C        -0.092  -0.143  -0.090  -0.107  -0.173  -0.075  -0.340  -0.391  -0.312
334   N         1.808   1.831   1.909   1.843   1.883   1.999   2.001   2.034   2.155
335   Y         1.808   1.831   1.909   1.875   1.911   2.030   2.001   2.034   2.155
336   L        -1.124  -1.118  -1.074  -1.214  -1.190  -1.117  -0.965  -0.952  -0.870
337   V         0.301   0.229   0.045   0.340   0.211  -0.105   0.284   0.175  -0.100
338   W         1.808   1.831   1.909   2.031   2.067   2.185   2.001   2.034   2.155
339   P         0.676   0.737   0.718   0.635   0.734   0.671   0.440   0.545   0.467
340   M        -0.750  -0.773  -0.672  -0.825  -0.877  -0.706  -0.809  -0.821  -0.689
341   V        -0.375  -0.358  -0.503  -0.224  -0.208  -0.409  -0.340  -0.318  -0.488
342   Q         1.808   1.831   1.909   1.967   2.002   2.122   2.001   2.034   2.155
343   F         1.032   0.936   0.828   0.997   0.865   0.694   1.065   0.900   0.677
344   I         0.676   0.737   0.718   0.469   0.578   0.510   0.440   0.545   0.467
345   N         1.808   1.831   1.909   1.843   1.883   1.999   2.001   2.034   2.155
346   F         1.808   1.831   1.909   1.713   1.748   1.870   2.001   2.034   2.155
347   L         0.301   0.164   0.064   0.220   0.023  -0.102   0.284   0.084  -0.073
348   I        -0.608  -0.532  -0.594  -0.856  -0.746  -0.804  -0.652  -0.555  -0.607
349   M        -0.233  -0.217  -0.146  -0.413  -0.388  -0.276  -0.496  -0.474  -0.379
350   P         1.808   1.831   1.909   1.945   1.971   2.100   2.001   2.034   2.155
351   R        -0.608  -0.684  -0.626  -0.484  -0.606  -0.501  -0.652  -0.725  -0.641
352   D        -0.608  -0.684  -0.626  -0.440  -0.544  -0.454  -0.652  -0.725  -0.641
353   F        -0.233  -0.176  -0.142  -0.678  -0.588  -0.530  -0.496  -0.414  -0.374
354   Q         1.032   0.992   0.867   1.280   1.232   1.059   1.065   0.995   0.750
355   A        -0.000   0.004  -0.051  -0.176  -0.239  -0.276  -0.184  -0.206  -0.255
356   P         1.808   1.831   1.909   1.945   1.971   2.100   2.001   2.034   2.155
357   F         1.808   1.831   1.909   1.713   1.748   1.870   2.001   2.034   2.155
358   S         1.032   0.936   0.828   1.059   0.936   0.752   1.065   0.900   0.677
359   S         1.808   1.831   1.909   1.774   1.820   1.931   2.001   2.034   2.155
360   S         0.301   0.164   0.064   0.387   0.198   0.040   0.284   0.084  -0.073
361   V         0.676   0.686   0.678   0.527   0.534   0.490   0.440   0.450   0.388
362   G         0.676   0.737   0.718   0.676   0.783   0.715   0.440   0.545   0.467
363   V         1.032   0.936   0.828   1.087   0.947   0.773   1.065   0.900   0.677
364   V        -0.608  -0.678  -0.622  -0.878  -0.979  -0.875  -0.652  -0.717  -0.636
365   W         1.808   1.831   1.909   2.031   2.067   2.185   2.001   2.034   2.155
366   N         0.676   0.612   0.657   0.584   0.462   0.513   0.440   0.307   0.347
367   C         0.676   0.612   0.657   0.822   0.694   0.750   0.440   0.307   0.347
368   F         0.676   0.656   0.649   0.475   0.438   0.407   0.440   0.393   0.331
369   L         1.808   1.831   1.909   1.592   1.624   1.749   2.001   2.034   2.155
370   S         1.032   0.992   0.867   1.101   1.067   0.897   1.065   0.995   0.750
371   M         0.301   0.164   0.064   0.540   0.319   0.135   0.284   0.084  -0.073
372   R         1.032   0.936   0.828   1.194   1.052   0.887   1.065   0.900   0.677
373   N         1.808   1.831   1.909   1.843   1.883   1.999   2.001   2.034   2.155
374   A         0.516   0.556   0.618   0.319   0.390   0.473   0.128   0.196   0.268
375   S        -0.608  -0.620  -0.603  -0.608  -0.622  -0.578  -0.652  -0.667  -0.619
376   K        -1.145  -1.148  -1.093  -0.957  -0.968  -0.893  -0.973  -0.972  -0.885
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08743
Output conservation file - output/Q08743
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
