1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    M         1.731   1.744   1.857   1.914   1.935   2.104   1.911   1.932   2.115
19    -         0.026   0.025   0.010  -0.115  -0.110  -0.138  -0.173  -0.177  -0.221
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    P        -0.561  -0.595  -0.529  -0.662  -0.714  -0.636  -0.671  -0.707  -0.610
22    L        -0.916  -0.966  -0.950  -0.918  -0.994  -0.967  -0.823  -0.877  -0.829
23    F        -1.406  -1.408  -1.315  -1.295  -1.330  -1.191  -1.127  -1.127  -0.996
24    D        -0.195  -0.166  -0.392  -0.093  -0.055  -0.367  -0.183  -0.145  -0.432
25    L        -0.135  -0.148  -0.080  -0.370  -0.391  -0.296  -0.415  -0.437  -0.356
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    I        -0.135  -0.123  -0.065  -0.344  -0.328  -0.277  -0.415  -0.400  -0.334
37    S        -0.017  -0.063   0.006  -0.206  -0.267  -0.174  -0.299  -0.349  -0.251
38    P         1.055   0.984   0.886   1.067   0.976   0.842   1.097   0.978   0.767
39    K        -0.446  -0.416  -0.479  -0.508  -0.475  -0.531  -0.531  -0.496  -0.548
40    A        -0.135  -0.153  -0.077  -0.304  -0.346  -0.247  -0.415  -0.445  -0.352
41    F        -0.446  -0.519  -0.508  -0.401  -0.516  -0.515  -0.531  -0.616  -0.586
42    V        -1.068  -1.082  -0.974  -1.004  -1.027  -0.858  -0.997  -1.002  -0.857
43    K        -0.639  -0.675  -0.566  -0.758  -0.798  -0.636  -0.764  -0.796  -0.652
44    L        -0.195  -0.281  -0.425  -0.144  -0.263  -0.482  -0.183  -0.293  -0.473
45    V         0.411   0.484   0.188   0.421   0.518   0.111   0.399   0.503   0.051
46    A        -0.017  -0.004   0.005  -0.313  -0.297  -0.265  -0.299  -0.284  -0.252
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    S         0.026   0.016   0.007  -0.195  -0.210  -0.248  -0.173  -0.191  -0.226
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    E        -0.655  -0.677  -0.571  -0.845  -0.867  -0.714  -0.777  -0.796  -0.656
55    K        -1.406  -1.392  -1.304  -1.409  -1.385  -1.261  -1.127  -1.114  -0.987
56    V        -1.261  -1.239  -1.243  -1.182  -1.153  -1.163  -0.997  -0.975  -0.936
57    H        -1.261  -1.239  -1.243  -1.059  -1.021  -1.019  -0.997  -0.975  -0.936
58    R         0.116   0.081   0.039   0.159   0.104  -0.003  -0.066  -0.117  -0.192
59    I        -0.135  -0.141  -0.060  -0.292  -0.306  -0.196  -0.415  -0.429  -0.327
60    V        -0.017  -0.036   0.005  -0.185  -0.212  -0.151  -0.299  -0.320  -0.252
61    P        -0.195  -0.301  -0.422  -0.103  -0.260  -0.463  -0.183  -0.318  -0.469
62    V        -0.639  -0.660  -0.576  -0.794  -0.829  -0.699  -0.764  -0.784  -0.662
63    D         1.055   1.070   0.899   1.141   1.163   0.970   1.097   1.120   0.792
64    A         0.722   0.799   0.759   0.601   0.723   0.622   0.515   0.653   0.520
65    T         0.722   0.756   0.719   0.642   0.698   0.583   0.515   0.573   0.440
66    W         1.731   1.744   1.857   1.926   1.945   2.116   1.911   1.932   2.115
67    Y         1.055   1.070   0.899   1.241   1.264   1.040   1.097   1.120   0.792
68    L         0.722   0.741   0.727   0.596   0.627   0.604   0.515   0.545   0.456
69    P         1.731   1.744   1.857   1.653   1.670   1.844   1.911   1.932   2.115
70    S         0.116   0.080   0.034   0.172   0.102   0.014  -0.066  -0.134  -0.197
71    W        -1.379  -1.367  -1.298  -1.326  -1.293  -1.189  -1.113  -1.098  -0.985
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    K        -0.950  -0.973  -0.931  -0.971  -1.006  -0.923  -0.880  -0.899  -0.815
76    L        -0.522  -0.479  -0.503  -0.573  -0.527  -0.541  -0.648  -0.599  -0.585
77    D        -0.446  -0.369  -0.473  -0.368  -0.244  -0.424  -0.531  -0.433  -0.540
78    N         0.116   0.107   0.042   0.112   0.083  -0.005  -0.066  -0.089  -0.186
79    K         0.411   0.390   0.173   0.445   0.422   0.108   0.399   0.368   0.028
80    V        -0.522  -0.550  -0.507  -0.478  -0.520  -0.461  -0.648  -0.671  -0.590
81    D        -0.757  -0.740  -0.854  -0.549  -0.524  -0.686  -0.648  -0.627  -0.731
82    F         0.722   0.668   0.695   0.742   0.651   0.671   0.515   0.406   0.391
83    L        -0.135  -0.124  -0.062  -0.294  -0.277  -0.182  -0.415  -0.402  -0.330
84    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    K        -0.017   0.028   0.010  -0.247  -0.194  -0.199  -0.299  -0.252  -0.245
86    P        -0.950  -0.966  -0.931  -1.035  -1.071  -1.027  -0.880  -0.895  -0.816
87    R         1.731   1.744   1.857   1.817   1.837   2.008   1.911   1.932   2.115
88    I         0.722   0.713   0.704   0.613   0.593   0.525   0.515   0.493   0.410
89    P         0.411   0.505   0.202   0.490   0.610   0.200   0.399   0.534   0.073
90    N        -0.446  -0.412  -0.483  -0.430  -0.387  -0.507  -0.531  -0.494  -0.555
91    S         0.722   0.726   0.707   0.601   0.600   0.520   0.515   0.517   0.416
92    I        -1.690  -1.707  -1.595  -1.499  -1.516  -1.365  -1.229  -1.237  -1.091
93    F         0.487   0.500   0.621   0.341   0.359   0.540   0.050   0.067   0.238
94    F         1.731   1.744   1.857   1.771   1.788   1.962   1.911   1.932   2.115
95    D         1.731   1.744   1.857   1.691   1.711   1.882   1.911   1.932   2.115
96    I         0.544   0.560   0.644   0.269   0.295   0.391   0.166   0.191   0.285
97    D         1.731   1.744   1.857   1.691   1.711   1.882   1.911   1.932   2.115
98    A        -1.379  -1.340  -1.282  -1.411  -1.362  -1.276  -1.113  -1.081  -0.972
99    I        -0.522  -0.567  -0.507  -0.562  -0.617  -0.513  -0.648  -0.687  -0.589
100   S        -1.050  -0.996  -0.956  -1.022  -0.962  -0.873  -0.975  -0.925  -0.840
101   D         0.411   0.420   0.182   0.521   0.537   0.191   0.399   0.410   0.041
102   K        -1.690  -1.673  -1.579  -1.470  -1.436  -1.303  -1.229  -1.214  -1.080
103   K        -1.261  -1.230  -1.244  -1.111  -1.072  -1.085  -0.997  -0.965  -0.937
104   S         1.055   0.984   0.886   1.015   0.931   0.804   1.097   0.978   0.767
105   P        -0.446  -0.394  -0.454  -0.468  -0.384  -0.465  -0.531  -0.456  -0.516
106   Y         0.116   0.066   0.042   0.204   0.136   0.061  -0.066  -0.128  -0.186
107   P         1.731   1.744   1.857   1.653   1.670   1.844   1.911   1.932   2.115
108   H         1.731   1.744   1.857   1.924   1.941   2.114   1.911   1.932   2.115
109   M         1.731   1.744   1.857   1.914   1.935   2.104   1.911   1.932   2.115
110   F         0.411   0.484   0.188   0.430   0.526   0.128   0.399   0.503   0.051
111   P         1.731   1.744   1.857   1.653   1.670   1.844   1.911   1.932   2.115
112   T        -0.639  -0.607  -0.553  -0.849  -0.801  -0.714  -0.764  -0.726  -0.638
113   K        -1.690  -1.707  -1.595  -1.635  -1.660  -1.496  -1.229  -1.237  -1.091
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   K        -1.068  -1.047  -0.964  -1.164  -1.126  -0.993  -0.997  -0.976  -0.849
116   V        -0.950  -0.975  -0.936  -0.884  -0.923  -0.877  -0.880  -0.901  -0.820
117   F         1.055   1.045   0.896   1.214   1.204   1.031   1.097   1.079   0.786
118   D        -0.639  -0.647  -0.570  -0.684  -0.714  -0.597  -0.764  -0.775  -0.657
119   D        -1.690  -1.700  -1.585  -1.543  -1.555  -1.389  -1.229  -1.232  -1.085
120   A        -0.950  -0.953  -0.915  -0.945  -0.935  -0.887  -0.880  -0.876  -0.800
121   M        -0.195  -0.301  -0.422   0.169   0.019  -0.203  -0.183  -0.318  -0.469
122   S        -0.446  -0.509  -0.506  -0.538  -0.626  -0.630  -0.531  -0.602  -0.583
123   N        -1.068  -1.026  -0.970  -1.083  -1.040  -0.916  -0.997  -0.959  -0.854
124   L         1.731   1.744   1.857   1.586   1.607   1.778   1.911   1.932   2.115
125   G         1.055   1.045   0.896   1.149   1.137   0.964   1.097   1.079   0.786
126   V        -0.211  -0.192  -0.090  -0.496  -0.464  -0.329  -0.531  -0.508  -0.372
127   Q        -1.379  -1.385  -1.288  -1.162  -1.174  -1.044  -1.113  -1.113  -0.977
128   K        -0.522  -0.541  -0.516  -0.617  -0.630  -0.605  -0.648  -0.661  -0.597
129   D        -0.639  -0.615  -0.560  -0.742  -0.701  -0.632  -0.764  -0.740  -0.647
130   D         0.411   0.312   0.152   0.512   0.381   0.127   0.399   0.253  -0.004
131   I        -0.950  -1.008  -0.947  -0.892  -0.974  -0.899  -0.880  -0.930  -0.831
132   L        -0.135  -0.169  -0.080  -0.401  -0.459  -0.334  -0.415  -0.469  -0.356
133   V         1.055   0.984   0.886   1.091   1.002   0.864   1.097   0.978   0.767
134   V         0.722   0.688   0.699   0.617   0.558   0.543   0.515   0.445   0.400
135   Y         1.731   1.744   1.857   1.819   1.840   2.010   1.911   1.932   2.115
136   D         1.731   1.744   1.857   1.691   1.711   1.882   1.911   1.932   2.115
137   R        -0.446  -0.455  -0.492  -0.384  -0.394  -0.483  -0.531  -0.539  -0.564
138   V        -1.379  -1.383  -1.298  -1.271  -1.273  -1.185  -1.113  -1.111  -0.984
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   G         1.731   1.744   1.857   1.708   1.723   1.899   1.911   1.932   2.115
142   N        -0.522  -0.575  -0.523  -0.494  -0.562  -0.480  -0.648  -0.695  -0.605
143   F         1.731   1.744   1.857   1.771   1.788   1.962   1.911   1.932   2.115
144   S         1.731   1.744   1.857   1.588   1.609   1.780   1.911   1.932   2.115
145   S        -0.017  -0.014   0.018  -0.254  -0.239  -0.180  -0.299  -0.280  -0.230
146   P         1.731   1.744   1.857   1.653   1.670   1.844   1.911   1.932   2.115
147   R         1.731   1.744   1.857   1.817   1.837   2.008   1.911   1.932   2.115
148   C        -0.639  -0.660  -0.576  -0.586  -0.636  -0.535  -0.764  -0.784  -0.662
149   A        -0.195  -0.281  -0.425  -0.024  -0.149  -0.369  -0.183  -0.293  -0.473
150   W         1.731   1.744   1.857   1.926   1.945   2.116   1.911   1.932   2.115
151   T         1.055   1.103   0.905   1.170   1.230   0.984   1.097   1.171   0.803
152   L        -0.017  -0.018  -0.004  -0.167  -0.164  -0.093  -0.299  -0.308  -0.263
153   G        -0.950  -0.865  -0.922  -1.056  -0.935  -1.010  -0.880  -0.795  -0.807
154   V         0.116   0.181   0.067   0.062   0.148  -0.003  -0.066   0.020  -0.145
155   M        -0.446  -0.359  -0.466  -0.323  -0.183  -0.316  -0.531  -0.415  -0.531
156   G         1.731   1.744   1.857   1.708   1.723   1.899   1.911   1.932   2.115
157   H         1.731   1.744   1.857   1.924   1.941   2.114   1.911   1.932   2.115
158   P        -0.446  -0.464  -0.481  -0.464  -0.492  -0.511  -0.531  -0.551  -0.554
159   K        -0.757  -0.752  -0.858  -0.609  -0.594  -0.746  -0.648  -0.646  -0.735
160   V         1.731   1.744   1.857   1.676   1.695   1.868   1.911   1.932   2.115
161   Y        -0.195  -0.281  -0.425   0.174   0.063  -0.125  -0.183  -0.293  -0.473
162   L         0.411   0.390   0.173   0.433   0.410   0.109   0.399   0.368   0.028
163   L         1.055   0.984   0.886   1.009   0.924   0.794   1.097   0.978   0.767
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   N         0.722   0.741   0.727   0.725   0.753   0.693   0.515   0.545   0.456
166   N         0.411   0.312   0.152   0.629   0.494   0.250   0.399   0.253  -0.004
167   F         0.722   0.741   0.727   0.742   0.768   0.727   0.515   0.545   0.456
168   N        -0.757  -0.749  -0.847  -0.558  -0.549  -0.752  -0.648  -0.638  -0.723
169   Q        -0.757  -0.728  -0.858  -0.529  -0.493  -0.680  -0.648  -0.614  -0.735
170   Y         0.116   0.133   0.043   0.261   0.279   0.141  -0.066  -0.061  -0.182
171   R        -0.195  -0.206  -0.398  -0.088  -0.103  -0.367  -0.183  -0.196  -0.438
172   E        -1.068  -1.060  -0.967  -1.068  -1.033  -0.920  -0.997  -0.986  -0.851
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   F        -0.950  -0.929  -0.914  -0.958  -0.925  -0.896  -0.880  -0.855  -0.800
175   K         0.116   0.140   0.056   0.066   0.099  -0.048  -0.066  -0.032  -0.160
176   Y         0.116   0.059   0.026   0.159   0.063  -0.021  -0.066  -0.154  -0.208
177   P         1.055   0.984   0.886   1.061   0.969   0.829   1.097   0.978   0.767
178   L        -0.339  -0.316  -0.435  -0.361  -0.326  -0.511  -0.368  -0.339  -0.485
179   D         0.506   0.524   0.631   0.205   0.237   0.387   0.088   0.118   0.258
180   S         0.016   0.007   0.005  -0.077  -0.089  -0.122  -0.216  -0.227  -0.240
181   S        -0.950  -0.914  -0.924  -0.987  -0.942  -0.937  -0.880  -0.850  -0.810
182   K        -0.757  -0.842  -0.892  -0.636  -0.763  -0.835  -0.648  -0.742  -0.770
183   V        -0.522  -0.452  -0.500  -0.570  -0.491  -0.496  -0.648  -0.576  -0.582
184   A        -1.261  -1.320  -1.271  -0.970  -1.057  -0.992  -0.997  -1.049  -0.960
185   A        -1.068  -1.038  -0.967  -1.160  -1.108  -1.011  -0.997  -0.968  -0.851
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   F        -1.379  -1.367  -1.294  -1.263  -1.254  -1.154  -1.113  -1.100  -0.982
200   S        -1.379  -1.409  -1.299  -1.327  -1.376  -1.225  -1.113  -1.131  -0.985
201   P         0.411   0.478   0.196   0.561   0.642   0.317   0.399   0.495   0.064
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   Y         0.995   0.962   0.863   1.159   1.116   0.959   0.999   0.941   0.723
207   P        -0.205  -0.210  -0.093  -0.541  -0.557  -0.389  -0.520  -0.529  -0.376
208   K        -1.406  -1.417  -1.315  -1.371  -1.403  -1.235  -1.127  -1.134  -0.996
209   S        -0.757  -0.842  -0.892  -0.697  -0.824  -0.914  -0.648  -0.742  -0.770
210   H        -0.950  -0.935  -0.925  -0.840  -0.835  -0.765  -0.880  -0.870  -0.811
211   Y         0.523   0.520   0.629   0.330   0.311   0.463   0.125   0.108   0.254
212   E        -1.157  -1.143  -1.012  -1.198  -1.161  -0.991  -1.066  -1.050  -0.888
213   S         0.026  -0.009  -0.025  -0.106  -0.161  -0.202  -0.173  -0.228  -0.274
214   S        -1.157  -1.143  -1.012  -1.306  -1.281  -1.099  -1.066  -1.050  -0.888
215   E         0.026   0.088   0.007  -0.030   0.070  -0.087  -0.173  -0.082  -0.226
216   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   F        -0.950  -0.952  -0.930  -0.871  -0.871  -0.808  -0.880  -0.878  -0.815
218   Q        -1.379  -1.334  -1.295  -0.982  -0.930  -0.846  -1.113  -1.075  -0.982
219   D        -1.068  -1.036  -0.963  -1.164  -1.127  -1.000  -0.997  -0.966  -0.848
220   K        -1.068  -1.048  -0.970  -1.083  -1.048  -0.912  -0.997  -0.976  -0.854
221   E        -1.068  -1.028  -0.973  -1.059  -1.016  -0.924  -0.997  -0.960  -0.856
222   I         0.411   0.480   0.191   0.518   0.607   0.213   0.399   0.498   0.055
223   V        -0.639  -0.651  -0.565  -0.766  -0.788  -0.666  -0.764  -0.773  -0.651
224   D        -0.446  -0.393  -0.475  -0.541  -0.460  -0.580  -0.531  -0.464  -0.545
225   Y         0.487   0.501   0.622   0.341   0.360   0.540   0.050   0.070   0.240
226   E         1.055   0.984   0.886   1.083   0.995   0.853   1.097   0.978   0.767
227   E        -0.017   0.025   0.009  -0.152  -0.108  -0.079  -0.299  -0.257  -0.247
228   M        -0.639  -0.676  -0.576  -0.642  -0.700  -0.578  -0.764  -0.797  -0.662
229   F        -0.757  -0.758  -0.865  -0.607  -0.616  -0.738  -0.648  -0.651  -0.743
230   Q        -1.068  -1.075  -0.966  -1.049  -1.056  -0.900  -0.997  -0.996  -0.851
231   L         0.116   0.059   0.026  -0.030  -0.117  -0.175  -0.066  -0.154  -0.208
232   V         0.116   0.105   0.034   0.069   0.045  -0.069  -0.066  -0.089  -0.198
233   K        -0.950  -0.904  -0.915  -1.001  -0.917  -0.949  -0.880  -0.828  -0.799
234   S        -0.446  -0.415  -0.474  -0.574  -0.543  -0.617  -0.531  -0.505  -0.545
235   G        -0.757  -0.842  -0.892  -0.581  -0.715  -0.814  -0.648  -0.742  -0.770
236   E        -1.068  -1.067  -0.973  -1.179  -1.168  -1.032  -0.997  -0.990  -0.856
237   L        -1.261  -1.296  -1.261  -1.192  -1.248  -1.200  -0.997  -1.028  -0.951
238   A        -1.050  -1.017  -0.952  -1.077  -1.030  -0.935  -0.975  -0.942  -0.836
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   K         0.995   0.939   0.846   0.966   0.895   0.766   0.999   0.902   0.691
245   K        -1.050  -1.042  -0.968  -1.157  -1.148  -1.034  -0.975  -0.964  -0.850
246   F        -0.017  -0.013  -0.004  -0.066  -0.074  -0.037  -0.299  -0.301  -0.263
247   N        -1.379  -1.401  -1.296  -1.068  -1.090  -0.957  -1.113  -1.125  -0.983
248   A        -1.379  -1.367  -1.298  -1.305  -1.286  -1.189  -1.113  -1.098  -0.985
249   F        -0.950  -0.964  -0.917  -0.936  -0.958  -0.871  -0.880  -0.889  -0.803
250   D         1.731   1.744   1.857   1.691   1.711   1.882   1.911   1.932   2.115
251   A         1.731   1.744   1.857   1.702   1.715   1.893   1.911   1.932   2.115
252   R         1.731   1.744   1.857   1.817   1.837   2.008   1.911   1.932   2.115
253   S         0.116   0.081   0.039  -0.030  -0.082  -0.161  -0.066  -0.117  -0.192
254   L        -0.757  -0.803  -0.881  -0.655  -0.706  -0.831  -0.648  -0.700  -0.759
255   G        -0.950  -0.919  -0.916  -0.837  -0.809  -0.767  -0.880  -0.850  -0.800
256   R         1.731   1.744   1.857   1.817   1.837   2.008   1.911   1.932   2.115
257   F         1.055   1.070   0.899   1.216   1.235   1.038   1.097   1.120   0.792
258   E        -1.068  -1.090  -0.971  -1.187  -1.215  -1.046  -0.997  -1.008  -0.855
259   G         1.731   1.744   1.857   1.708   1.723   1.899   1.911   1.932   2.115
260   T        -0.950  -0.932  -0.916  -0.941  -0.914  -0.881  -0.880  -0.862  -0.803
261   E        -0.950  -0.983  -0.930  -0.967  -1.018  -0.957  -0.880  -0.908  -0.816
262   P         0.411   0.367   0.167   0.502   0.444   0.168   0.399   0.335   0.020
263   E         1.731   1.744   1.857   1.672   1.692   1.863   1.911   1.932   2.115
264   P         1.055   0.984   0.886   1.049   0.955   0.804   1.097   0.978   0.767
265   R         1.731   1.744   1.857   1.817   1.837   2.008   1.911   1.932   2.115
266   S        -0.195  -0.206  -0.398  -0.111  -0.127  -0.436  -0.183  -0.196  -0.438
267   D         0.116   0.127   0.065   0.085   0.110  -0.004  -0.066  -0.039  -0.146
268   I         0.722   0.772   0.742   0.529   0.609   0.537   0.515   0.603   0.486
269   P         0.411   0.354   0.165   0.412   0.338   0.056   0.399   0.313   0.016
270   S         1.731   1.744   1.857   1.588   1.609   1.780   1.911   1.932   2.115
271   G         1.731   1.744   1.857   1.708   1.723   1.899   1.911   1.932   2.115
272   H         1.731   1.744   1.857   1.924   1.941   2.114   1.911   1.932   2.115
273   I         0.116   0.137   0.057   0.131   0.164   0.050  -0.066  -0.035  -0.162
274   P         1.055   1.125   0.909   1.065   1.150   0.875   1.097   1.206   0.811
275   G         0.411   0.378   0.172   0.529   0.483   0.175   0.399   0.347   0.026
276   T        -0.639  -0.609  -0.554  -0.831  -0.785  -0.694  -0.764  -0.728  -0.638
277   Q        -0.522  -0.507  -0.509  -0.434  -0.415  -0.415  -0.648  -0.627  -0.590
278   P        -0.211  -0.195  -0.089  -0.453  -0.421  -0.278  -0.531  -0.510  -0.370
279   L         0.544   0.528   0.631   0.223   0.192   0.341   0.166   0.126   0.259
280   P         1.055   1.029   0.894   1.065   1.033   0.851   1.097   1.054   0.782
281   Y         1.055   1.076   0.898   1.201   1.227   1.006   1.097   1.129   0.790
282   G        -1.379  -1.365  -1.284  -1.366  -1.337  -1.229  -1.113  -1.098  -0.974
283   S        -0.757  -0.728  -0.858  -0.650  -0.605  -0.839  -0.648  -0.614  -0.735
284   L        -0.446  -0.457  -0.481  -0.498  -0.517  -0.559  -0.531  -0.547  -0.553
285   L         0.411   0.312   0.152   0.421   0.294   0.056   0.399   0.253  -0.004
286   D        -0.950  -0.998  -0.929  -0.861  -0.927  -0.830  -0.880  -0.918  -0.815
287   P        -1.379  -1.410  -1.291  -1.223  -1.270  -1.101  -1.113  -1.131  -0.979
288   E        -1.379  -1.326  -1.288  -1.368  -1.284  -1.233  -1.113  -1.067  -0.977
289   T        -0.655  -0.676  -0.565  -0.697  -0.725  -0.563  -0.777  -0.795  -0.649
290   K        -0.561  -0.576  -0.535  -0.660  -0.678  -0.626  -0.671  -0.689  -0.614
291   T        -0.446  -0.503  -0.508  -0.372  -0.466  -0.468  -0.531  -0.603  -0.586
292   Y         0.116   0.079   0.050   0.189   0.142   0.078  -0.066  -0.107  -0.173
293   P        -0.446  -0.369  -0.473  -0.557  -0.440  -0.602  -0.531  -0.433  -0.540
294   E        -0.950  -0.929  -0.923  -0.958  -0.940  -0.889  -0.880  -0.864  -0.809
295   A        -1.068  -1.049  -0.966  -1.185  -1.165  -1.033  -0.997  -0.978  -0.851
296   G        -0.950  -0.894  -0.911  -0.796  -0.721  -0.729  -0.880  -0.821  -0.798
297   E        -0.195  -0.203  -0.399  -0.088  -0.101  -0.414  -0.183  -0.196  -0.440
298   A        -0.757  -0.675  -0.846  -0.702  -0.583  -0.849  -0.648  -0.555  -0.722
299   I        -1.068  -1.087  -0.972  -1.051  -1.092  -0.932  -0.997  -1.006  -0.856
300   H        -1.261  -1.262  -1.240  -1.116  -1.125  -1.104  -0.997  -0.997  -0.933
301   A        -1.068  -1.056  -0.971  -1.234  -1.209  -1.081  -0.997  -0.981  -0.854
302   T         0.116   0.189   0.072   0.129   0.252   0.053  -0.066   0.051  -0.135
303   L        -1.690  -1.656  -1.581  -1.567  -1.522  -1.427  -1.229  -1.201  -1.082
304   E        -0.639  -0.647  -0.570  -0.634  -0.671  -0.551  -0.764  -0.775  -0.657
305   K        -0.950  -0.931  -0.914  -0.939  -0.895  -0.866  -0.880  -0.855  -0.800
306   A        -0.639  -0.603  -0.556  -0.674  -0.618  -0.540  -0.764  -0.714  -0.640
307   L        -1.068  -1.018  -0.962  -1.148  -1.090  -0.986  -0.997  -0.954  -0.847
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   L        -1.070  -0.974  -0.961  -1.026  -0.876  -0.880  -0.984  -0.883  -0.841
326   D         0.411   0.451   0.192   0.535   0.590   0.232   0.399   0.455   0.057
327   P        -1.261  -1.279  -1.257  -1.092  -1.132  -1.092  -0.997  -1.012  -0.948
328   S         0.411   0.451   0.192   0.410   0.465   0.096   0.399   0.455   0.057
329   K         1.055   0.984   0.886   1.021   0.930   0.790   1.097   0.978   0.767
330   P         1.055   1.045   0.896   1.066   1.054   0.856   1.097   1.079   0.786
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   T         0.544   0.590   0.667   0.352   0.432   0.530   0.166   0.252   0.332
339   I         1.731   1.744   1.857   1.715   1.732   1.906   1.911   1.932   2.115
340   C        -0.950  -0.956  -0.931  -0.908  -0.922  -0.858  -0.880  -0.887  -0.816
341   S         0.544   0.538   0.631   0.448   0.425   0.523   0.166   0.145   0.258
342   C         1.731   1.744   1.857   1.954   1.974   2.144   1.911   1.932   2.115
343   G         1.731   1.744   1.857   1.708   1.723   1.899   1.911   1.932   2.115
344   T         0.722   0.668   0.695   0.642   0.541   0.533   0.515   0.406   0.391
345   G         1.731   1.744   1.857   1.708   1.723   1.899   1.911   1.932   2.115
346   V         1.731   1.744   1.857   1.676   1.695   1.868   1.911   1.932   2.115
347   S         0.722   0.772   0.742   0.642   0.725   0.629   0.515   0.603   0.486
348   G         0.722   0.769   0.737   0.640   0.707   0.633   0.515   0.599   0.476
349   V        -0.017  -0.061   0.002  -0.047  -0.102  -0.003  -0.299  -0.346  -0.255
350   I         0.544   0.528   0.631   0.317   0.276   0.419   0.166   0.126   0.259
351   I         0.487   0.501   0.623   0.130   0.148   0.329   0.050   0.070   0.242
352   K        -0.950  -0.984  -0.924  -0.910  -0.951  -0.862  -0.880  -0.904  -0.810
353   T        -0.446  -0.509  -0.506  -0.431  -0.525  -0.542  -0.531  -0.602  -0.583
354   A         1.055   1.045   0.896   1.115   1.099   0.904   1.097   1.079   0.786
355   L         1.055   1.045   0.896   1.000   0.993   0.793   1.097   1.079   0.786
356   E         0.411   0.349   0.154   0.506   0.421   0.136   0.399   0.306  -0.001
357   L        -0.655  -0.615  -0.564  -0.712  -0.665  -0.573  -0.777  -0.734  -0.648
358   A        -0.211  -0.215  -0.094  -0.393  -0.379  -0.193  -0.531  -0.536  -0.377
359   G        -0.195  -0.171  -0.394   0.008   0.039  -0.273  -0.183  -0.151  -0.434
360   V        -0.639  -0.655  -0.575  -0.746  -0.769  -0.656  -0.764  -0.780  -0.662
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   P        -1.261  -1.258  -1.256  -1.209  -1.206  -1.225  -0.997  -0.991  -0.947
365   N        -1.068  -1.067  -0.970  -1.085  -1.084  -0.944  -0.997  -0.991  -0.854
366   V        -0.446  -0.425  -0.466  -0.455  -0.410  -0.489  -0.531  -0.494  -0.534
367   R         0.116   0.124   0.057   0.164   0.190   0.042  -0.066  -0.044  -0.164
368   L         0.544   0.590   0.667   0.234   0.325   0.410   0.166   0.252   0.332
369   Y         1.731   1.744   1.857   1.819   1.840   2.010   1.911   1.932   2.115
370   D         1.731   1.744   1.857   1.691   1.711   1.882   1.911   1.932   2.115
371   G         1.055   0.984   0.886   1.117   1.022   0.883   1.097   0.978   0.767
372   S         1.731   1.744   1.857   1.588   1.609   1.780   1.911   1.932   2.115
373   W         1.731   1.744   1.857   1.926   1.945   2.116   1.911   1.932   2.115
374   T         0.411   0.398   0.177   0.554   0.531   0.197   0.399   0.375   0.034
375   E         1.055   0.984   0.886   1.086   0.997   0.858   1.097   0.978   0.767
376   W         1.055   0.984   0.886   1.354   1.268   1.134   1.097   0.978   0.767
377   V        -0.017  -0.045   0.005  -0.175  -0.200  -0.122  -0.299  -0.317  -0.245
378   L        -0.950  -0.953  -0.922  -0.807  -0.810  -0.777  -0.880  -0.877  -0.807
379   K         0.722   0.769   0.737   0.721   0.799   0.698   0.515   0.599   0.476
380   S        -0.446  -0.369  -0.473  -0.494  -0.374  -0.544  -0.531  -0.433  -0.540
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   G        -0.639  -0.620  -0.560  -0.809  -0.781  -0.700  -0.764  -0.740  -0.646
384   P        -0.639  -0.622  -0.555  -0.859  -0.820  -0.725  -0.764  -0.735  -0.639
385   E        -0.695  -0.664  -0.581  -0.904  -0.869  -0.720  -0.823  -0.792  -0.669
386   W        -0.071  -0.056  -0.014  -0.171  -0.150  -0.059  -0.368  -0.349  -0.276
387   I         0.411   0.394   0.177   0.524   0.495   0.168   0.399   0.369   0.034
388   A        -0.757  -0.762  -0.871  -0.545  -0.556  -0.722  -0.648  -0.652  -0.749
389   E         0.411   0.354   0.165   0.447   0.372   0.099   0.399   0.313   0.016
390   N        -1.379  -1.363  -1.284  -1.262  -1.245  -1.123  -1.113  -1.096  -0.975
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   D        -1.690  -1.691  -1.579  -1.654  -1.656  -1.511  -1.229  -1.226  -1.080
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08686
Output conservation file - output/Q08686
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
