1     M         1.928   1.997   2.143   2.164   2.285   2.516   2.186   2.293   2.566
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.047  -0.982  -0.887  -1.106  -1.004  -0.877  -1.008  -0.923  -0.804
26    -        -1.404  -1.369  -1.276  -1.554  -1.523  -1.386  -1.166  -1.114  -0.988
27    L        -0.384  -0.305  -0.376  -0.479  -0.393  -0.492  -0.509  -0.418  -0.485
28    D        -0.384  -0.470  -0.427  -0.372  -0.565  -0.507  -0.509  -0.619  -0.547
29    P        -0.714  -0.779  -0.821  -0.595  -0.728  -0.869  -0.637  -0.714  -0.733
30    R        -2.036  -1.933  -1.845  -1.803  -1.643  -1.523  -1.407  -1.306  -1.180
31    I        -1.375  -1.296  -1.246  -1.408  -1.303  -1.208  -1.150  -1.062  -0.965
32    L        -0.118  -0.270  -0.340  -0.276  -0.485  -0.573  -0.124  -0.334  -0.423
33    P         0.212   0.092   0.150   0.223   0.024   0.062   0.005  -0.176  -0.125
34    Y         0.667   0.667   0.814   0.510   0.485   0.696   0.261   0.217   0.426
35    Y        -0.465  -0.301  -0.394  -0.560  -0.269  -0.470  -0.637  -0.417  -0.504
36    D         0.071   0.051   0.151   0.009   0.035   0.162  -0.252  -0.246  -0.125
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    P         0.625   0.454   0.342   0.890   0.665   0.466   0.665   0.406   0.203
44    A        -1.673  -1.626  -1.542  -1.493  -1.452  -1.288  -1.261  -1.198  -1.071
45    V         0.142   0.120   0.140  -0.187  -0.309  -0.259  -0.146  -0.194  -0.148
46    E        -0.792  -0.814  -0.845  -0.630  -0.703  -0.722  -0.754  -0.785  -0.767
47    R        -0.864  -0.670  -0.829  -0.804  -0.551  -0.713  -0.855  -0.640  -0.752
48    K         0.715   0.864   0.898   0.565   0.819   0.842   0.361   0.627   0.610
49    I        -0.094  -0.002   0.068  -0.370  -0.234  -0.137  -0.450  -0.334  -0.242
50    A         0.918   0.841   0.915   0.822   0.655   0.766   0.767   0.581   0.648
51    V         0.310   0.548   0.312  -0.011   0.352   0.011   0.158   0.535   0.149
52    V         0.715   0.762   0.853   0.507   0.585   0.687   0.361   0.419   0.513
53    T         1.928   1.997   2.143   1.940   2.045   2.288   2.186   2.293   2.566
54    G         1.928   1.997   2.143   1.911   2.014   2.258   2.186   2.293   2.566
55    G         0.625   0.539   0.354   0.719   0.604   0.317   0.665   0.533   0.223
56    N         0.142   0.073   0.169   0.016  -0.083   0.038  -0.146  -0.235  -0.110
57    T        -0.556  -0.681  -0.773  -0.420  -0.626  -0.777  -0.450  -0.599  -0.679
58    G         1.928   1.997   2.143   1.911   2.014   2.258   2.186   2.293   2.566
59    I         0.142   0.210   0.168  -0.187  -0.149  -0.196  -0.146  -0.087  -0.111
60    G         1.928   1.997   2.143   1.911   2.014   2.258   2.186   2.293   2.566
61    W        -0.792  -0.874  -0.830  -0.503  -0.638  -0.593  -0.754  -0.824  -0.752
62    Y        -0.262  -0.295  -0.370  -0.100  -0.182  -0.269  -0.349  -0.423  -0.476
63    T         0.918   0.937   0.911   0.838   0.857   0.760   0.767   0.772   0.639
64    V        -0.262  -0.405  -0.401  -0.259  -0.519  -0.516  -0.349  -0.537  -0.515
65    L         1.928   1.997   2.143   1.624   1.725   1.966   2.186   2.293   2.566
66    H        -0.262  -0.360  -0.381  -0.010  -0.204  -0.212  -0.349  -0.488  -0.490
67    L         1.263   1.217   1.130   1.039   0.996   0.885   1.375   1.287   1.092
68    Y         0.310   0.159   0.174   0.391   0.121   0.120   0.158  -0.090  -0.086
69    L        -0.094  -0.026   0.052  -0.479  -0.315  -0.194  -0.450  -0.361  -0.265
70    H         0.017  -0.231  -0.305   0.375   0.009  -0.163   0.057  -0.268  -0.376
71    G         1.263   1.217   1.130   1.335   1.293   1.191   1.375   1.287   1.092
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    F        -1.269  -1.380  -1.253  -1.045  -1.175  -0.995  -1.058  -1.120  -0.970
78    V        -1.269  -1.106  -1.176  -1.141  -0.897  -1.000  -1.058  -0.889  -0.907
79    V         0.918   0.841   0.915   0.874   0.736   0.815   0.767   0.581   0.648
80    Y         0.625   0.547   0.352   0.925   0.858   0.577   0.665   0.546   0.220
81    I         0.089   0.232   0.181  -0.369  -0.195  -0.217  -0.247  -0.077  -0.096
82    C        -0.571  -0.572  -0.447  -0.623  -0.633  -0.442  -0.754  -0.726  -0.574
83    G         0.017   0.006  -0.235   0.140   0.122  -0.253   0.057   0.042  -0.281
84    R         1.928   1.997   2.143   2.055   2.166   2.405   2.186   2.293   2.566
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    N         0.619   0.668   0.814   0.325   0.399   0.609   0.158   0.218   0.426
88    S        -0.792  -0.872  -0.829  -0.862  -0.990  -0.957  -0.754  -0.809  -0.746
89    H        -1.379  -1.323  -1.247  -1.405  -1.346  -1.250  -1.160  -1.077  -0.967
90    K         0.089   0.056   0.163  -0.043  -0.068   0.097  -0.247  -0.265  -0.120
91    I        -1.269  -1.228  -1.230  -1.161  -1.133  -1.079  -1.058  -1.007  -0.952
92    S        -0.975  -0.856  -0.843  -0.982  -0.719  -0.783  -0.957  -0.795  -0.763
93    K        -0.792  -0.683  -0.782  -0.698  -0.582  -0.676  -0.754  -0.642  -0.702
94    A        -0.262  -0.352  -0.334  -0.372  -0.533  -0.536  -0.349  -0.434  -0.421
95    I         0.918   0.970   0.921   0.929   1.023   0.921   0.767   0.837   0.661
96    Q        -0.864  -0.776  -0.797  -0.780  -0.672  -0.651  -0.855  -0.758  -0.725
97    E        -0.388  -0.493  -0.385  -0.332  -0.459  -0.284  -0.551  -0.643  -0.502
98    I         0.918   1.052   0.991   0.779   1.012   0.831   0.767   0.992   0.810
99    L        -1.086  -1.107  -1.168  -0.911  -0.928  -1.087  -0.855  -0.875  -0.891
100   A        -1.269  -1.222  -1.183  -1.199  -1.149  -1.062  -1.058  -0.987  -0.910
101   E         0.625   0.622   0.374   0.847   0.838   0.487   0.665   0.655   0.255
102   A         0.918   0.851   0.899   0.823   0.675   0.737   0.767   0.603   0.614
103   K        -1.673  -1.525  -1.523  -1.359  -1.144  -1.131  -1.261  -1.125  -1.059
104   K        -1.673  -1.517  -1.541  -1.511  -1.281  -1.295  -1.261  -1.115  -1.072
105   R        -0.499  -0.552  -0.451  -0.547  -0.633  -0.505  -0.653  -0.700  -0.575
106   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   S        -0.611  -0.518  -0.494  -0.620  -0.462  -0.460  -0.770  -0.644  -0.619
114   S        -0.083  -0.020   0.067  -0.581  -0.482  -0.337  -0.442  -0.355  -0.244
115   P        -1.026  -1.024  -0.905  -0.978  -1.003  -0.788  -0.998  -0.975  -0.824
116   G        -1.026  -1.027  -0.921  -1.194  -1.217  -1.078  -0.998  -0.977  -0.839
117   A        -1.404  -1.325  -1.276  -1.454  -1.305  -1.288  -1.166  -1.081  -0.988
118   G        -0.129  -0.010   0.065  -0.397  -0.230  -0.114  -0.495  -0.323  -0.244
119   P        -0.506  -0.356  -0.421  -0.517  -0.326  -0.385  -0.663  -0.489  -0.539
120   G        -0.506  -0.586  -0.455  -0.523  -0.645  -0.468  -0.663  -0.733  -0.576
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   P        -1.375  -1.347  -1.249  -1.498  -1.405  -1.291  -1.150  -1.102  -0.967
123   S        -0.920  -0.610  -0.831  -0.898  -0.476  -0.743  -0.893  -0.543  -0.748
124   I        -1.045  -1.077  -0.911  -1.138  -1.174  -0.938  -1.022  -1.016  -0.830
125   Q        -0.714  -0.830  -0.843  -0.472  -0.697  -0.711  -0.637  -0.770  -0.756
126   R        -1.375  -1.328  -1.254  -1.281  -1.217  -1.092  -1.150  -1.089  -0.971
127   L        -0.271  -0.391  -0.411  -0.456  -0.585  -0.627  -0.328  -0.502  -0.515
128   G         1.146   0.952   1.014   1.164   0.855   0.947   1.181   0.802   0.857
129   S        -1.375  -1.340  -1.248  -1.283  -1.203  -1.062  -1.150  -1.091  -0.966
130   L         0.715   0.684   0.823   0.194   0.134   0.346   0.361   0.253   0.446
131   H        -1.967  -1.850  -1.803  -1.597  -1.481  -1.355  -1.362  -1.253  -1.154
132   Y        -0.388  -0.361  -0.356  -0.357  -0.246  -0.265  -0.551  -0.469  -0.457
133   I         0.625   0.765   0.391   0.445   0.634   0.126   0.665   0.865   0.283
134   H        -0.864  -0.881  -0.818  -0.649  -0.662  -0.550  -0.855  -0.839  -0.739
135   L        -0.975  -0.885  -0.847  -1.280  -1.143  -1.059  -0.957  -0.840  -0.772
136   D         1.928   1.997   2.143   2.059   2.170   2.409   2.186   2.293   2.566
137   L         1.263   1.187   1.138   1.041   0.958   0.902   1.375   1.236   1.108
138   T        -0.388  -0.401  -0.369  -0.736  -0.798  -0.736  -0.551  -0.554  -0.485
139   D         0.142   0.193   0.168   0.061   0.105   0.091  -0.146  -0.102  -0.111
140   L         0.310   0.227   0.190  -0.002  -0.128  -0.178   0.158   0.005  -0.060
141   K        -1.269  -1.327  -1.228  -1.163  -1.244  -1.103  -1.058  -1.078  -0.950
142   C         0.918   1.137   1.028   0.898   1.218   1.077   0.767   1.147   0.886
143   V         0.625   0.547   0.352   0.739   0.649   0.296   0.665   0.546   0.220
144   E        -1.673  -1.679  -1.553  -1.589  -1.588  -1.444  -1.261  -1.231  -1.080
145   R        -1.379  -1.364  -1.241  -1.323  -1.303  -1.109  -1.160  -1.112  -0.962
146   A         0.625   0.520   0.362   0.731   0.574   0.356   0.665   0.504   0.236
147   A         0.310   0.398   0.259   0.272   0.400   0.199   0.158   0.304   0.061
148   L        -1.673  -1.585  -1.531  -1.622  -1.459  -1.415  -1.261  -1.169  -1.064
149   K        -0.792  -0.827  -0.821  -0.711  -0.767  -0.757  -0.754  -0.777  -0.744
150   I        -0.499  -0.481  -0.416  -0.715  -0.701  -0.649  -0.653  -0.616  -0.532
151   L        -0.792  -0.729  -0.798  -1.026  -0.926  -0.997  -0.754  -0.663  -0.712
152   K        -1.673  -1.547  -1.539  -1.578  -1.414  -1.373  -1.261  -1.136  -1.070
153   L        -1.673  -1.569  -1.537  -1.658  -1.500  -1.401  -1.261  -1.154  -1.068
154   E         1.263   1.217   1.130   1.431   1.376   1.259   1.375   1.287   1.092
155   D        -0.384  -0.280  -0.375  -0.283  -0.181  -0.279  -0.509  -0.418  -0.483
156   H         0.142   0.075   0.146   0.185   0.067   0.176  -0.146  -0.243  -0.140
157   I         0.918   0.958   0.926   0.541   0.599   0.517   0.767   0.814   0.671
158   D         0.310   0.386   0.223   0.476   0.582   0.350   0.158   0.244  -0.009
159   V         0.142   0.281   0.222  -0.067   0.208   0.049  -0.146   0.102  -0.007
160   L         1.928   1.997   2.143   1.624   1.725   1.966   2.186   2.293   2.566
161   V         0.142   0.140   0.186   0.028   0.078   0.133  -0.146  -0.124  -0.077
162   N         0.017  -0.167  -0.282   0.297   0.063  -0.141   0.057  -0.185  -0.345
163   N         1.928   1.997   2.143   2.024   2.148   2.374   2.186   2.293   2.566
164   A         1.928   1.997   2.143   1.909   1.991   2.256   2.186   2.293   2.566
165   G         1.263   1.398   1.153   1.313   1.498   1.180   1.375   1.584   1.137
166   I         0.142   0.329   0.225  -0.018   0.311   0.134  -0.146   0.154  -0.008
167   M         1.263   1.187   1.138   1.567   1.489   1.409   1.375   1.236   1.108
168   A         1.263   1.208   1.132   1.326   1.251   1.177   1.375   1.272   1.095
169   V        -0.975  -1.019  -0.883  -1.216  -1.249  -1.065  -0.957  -0.965  -0.806
170   P         1.263   1.217   1.130   1.480   1.434   1.308   1.375   1.287   1.092
171   L        -0.792  -0.914  -0.844  -0.783  -0.983  -0.937  -0.754  -0.861  -0.766
172   E        -0.262  -0.218  -0.354  -0.206  -0.208  -0.387  -0.349  -0.329  -0.453
173   M        -1.269  -1.253  -1.194  -1.431  -1.405  -1.276  -1.058  -1.015  -0.919
174   T         0.918   0.877   0.907   0.838   0.750   0.752   0.767   0.654   0.630
175   K         0.017  -0.101  -0.258   0.225   0.055  -0.193   0.057  -0.102  -0.313
176   D         1.263   1.217   1.130   1.477   1.438   1.324   1.375   1.287   1.092
177   G         0.625   0.831   0.409   0.747   1.020   0.464   0.665   0.966   0.312
178   F         0.142   0.120   0.140   0.132   0.115   0.174  -0.146  -0.194  -0.148
179   E         1.928   1.997   2.143   2.028   2.126   2.378   2.186   2.293   2.566
180   V         0.310   0.307   0.235   0.255   0.267   0.075   0.158   0.170   0.015
181   Q         1.928   1.997   2.143   2.130   2.237   2.481   2.186   2.293   2.566
182   L        -0.499  -0.528  -0.442  -0.557  -0.574  -0.529  -0.653  -0.675  -0.564
183   Q         0.625   0.454   0.342   0.940   0.703   0.510   0.665   0.406   0.203
184   T         1.928   1.997   2.143   1.940   2.045   2.288   2.186   2.293   2.566
185   N         1.928   1.997   2.143   2.024   2.148   2.374   2.186   2.293   2.566
186   Y         0.017  -0.101  -0.258   0.347   0.207  -0.040   0.057  -0.102  -0.313
187   I        -0.094  -0.056   0.081  -0.490  -0.465  -0.267  -0.450  -0.392  -0.219
188   S         0.031   0.024   0.092  -0.210  -0.259  -0.173  -0.247  -0.275  -0.201
189   H         0.715   0.801   0.862   0.734   0.887   0.938   0.361   0.499   0.532
190   F        -0.262  -0.353  -0.381  -0.249  -0.420  -0.503  -0.349  -0.481  -0.488
191   I         0.310   0.479   0.244  -0.020   0.208  -0.124   0.158   0.386   0.027
192   F         0.918   0.972   0.923   0.557   0.641   0.540   0.767   0.841   0.666
193   T         1.263   1.187   1.138   1.350   1.265   1.200   1.375   1.236   1.108
194   M        -1.269  -1.380  -1.253  -1.000  -1.155  -0.982  -1.058  -1.120  -0.970
195   R        -0.094  -0.100   0.044  -0.402  -0.477  -0.270  -0.450  -0.459  -0.276
196   L         1.928   1.997   2.143   1.624   1.725   1.966   2.186   2.293   2.566
197   L         1.928   1.997   2.143   1.624   1.725   1.966   2.186   2.293   2.566
198   P         1.263   1.289   1.132   1.498   1.557   1.354   1.375   1.410   1.097
199   L         0.625   0.614   0.377   0.442   0.432   0.096   0.665   0.642   0.260
200   L         1.263   1.438   1.155   1.032   1.260   0.909   1.375   1.645   1.142
201   -        -0.606  -0.529  -0.453  -0.706  -0.590  -0.498  -0.779  -0.679  -0.576
202   -         0.117   0.183   0.187   0.059   0.167   0.137  -0.113  -0.020  -0.048
203   -         0.645   0.708   0.834   0.297   0.396   0.574   0.215   0.306   0.471
204   -         0.117   0.184   0.202  -0.105  -0.010  -0.007  -0.113  -0.017  -0.024
205   -        -0.611  -0.560  -0.453  -0.682  -0.611  -0.451  -0.770  -0.699  -0.569
206   -        -0.611  -0.523  -0.470  -0.965  -0.803  -0.784  -0.770  -0.652  -0.590
207   -        -0.611  -0.606  -0.494  -0.653  -0.645  -0.494  -0.770  -0.754  -0.619
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   R         0.071   0.021   0.137  -0.055  -0.118   0.058  -0.252  -0.299  -0.149
223   H        -1.375  -1.159  -1.235  -1.318  -1.011  -1.108  -1.150  -0.939  -0.957
224   C        -0.920  -0.672  -0.815  -0.816  -0.492  -0.649  -0.893  -0.639  -0.737
225   R        -1.375  -1.159  -1.235  -1.191  -0.880  -0.968  -1.150  -0.939  -0.957
226   G        -0.571  -0.599  -0.464  -0.721  -0.751  -0.551  -0.754  -0.757  -0.591
227   R         1.263   1.398   1.153   1.467   1.657   1.343   1.375   1.584   1.137
228   I         0.715   0.810   0.863   0.506   0.678   0.708   0.361   0.519   0.535
229   I         0.619   0.667   0.814   0.309   0.389   0.603   0.158   0.218   0.426
230   S        -0.975  -0.992  -0.873  -0.972  -0.950  -0.808  -0.957  -0.938  -0.796
231   L         0.918   0.965   0.924   0.542   0.611   0.515   0.767   0.828   0.667
232   S         0.310   0.216   0.216   0.229   0.075   0.044   0.158   0.013  -0.020
233   S         1.928   1.997   2.143   1.903   2.012   2.250   2.186   2.293   2.566
234   I        -0.792  -0.790  -0.784  -0.858  -0.772  -0.823  -0.754  -0.718  -0.696
235   G         1.263   1.208   1.132   1.314   1.248   1.146   1.375   1.272   1.095
236   H         0.918   0.836   0.907   1.088   0.950   1.023   0.767   0.572   0.631
237   H        -0.975  -0.928  -0.887  -0.847  -0.817  -0.749  -0.957  -0.896  -0.809
238   L        -0.792  -0.823  -0.804  -0.950  -0.945  -0.898  -0.754  -0.776  -0.724
239   E        -0.262  -0.083  -0.285  -0.251   0.012  -0.257  -0.349  -0.094  -0.355
240   F        -0.792  -0.872  -0.853  -0.679  -0.781  -0.796  -0.754  -0.835  -0.776
241   M        -1.562  -1.545  -1.514  -1.356  -1.390  -1.304  -1.160  -1.129  -1.047
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   Y        -0.792  -0.822  -0.849  -0.723  -0.839  -0.876  -0.754  -0.792  -0.772
249   W        -1.269  -0.993  -1.195  -1.126  -0.760  -0.981  -1.058  -0.773  -0.920
250   K        -0.975  -0.980  -0.886  -0.950  -0.923  -0.796  -0.957  -0.931  -0.808
251   L        -0.556  -0.691  -0.781  -0.648  -0.846  -0.943  -0.450  -0.609  -0.688
252   S        -1.379  -1.283  -1.241  -1.448  -1.307  -1.256  -1.160  -1.052  -0.963
253   K        -1.269  -1.131  -1.186  -1.208  -1.020  -1.071  -1.058  -0.909  -0.914
254   T        -1.086  -1.122  -1.153  -0.816  -0.880  -0.899  -0.855  -0.883  -0.876
255   W        -0.975  -0.906  -0.842  -1.093  -1.004  -0.876  -0.957  -0.844  -0.761
256   D         0.031   0.025   0.094  -0.021  -0.042   0.038  -0.247  -0.273  -0.198
257   Y        -1.086  -1.251  -1.213  -0.839  -1.145  -1.116  -0.855  -1.003  -0.933
258   K        -1.673  -1.516  -1.541  -1.337  -1.106  -1.121  -1.261  -1.114  -1.072
259   P         0.017  -0.231  -0.305   0.389   0.072  -0.048   0.057  -0.268  -0.376
260   N        -0.792  -0.924  -0.848  -0.809  -1.047  -0.990  -0.754  -0.870  -0.771
261   M        -1.379  -1.352  -1.244  -1.485  -1.507  -1.320  -1.160  -1.101  -0.965
262   L        -1.379  -1.291  -1.235  -1.468  -1.291  -1.235  -1.160  -1.059  -0.958
263   F        -0.556  -0.795  -0.815  -0.326  -0.690  -0.784  -0.450  -0.715  -0.726
264   T         0.017   0.015  -0.228   0.230   0.222  -0.101   0.057   0.048  -0.272
265   W         0.918   0.889   0.903   1.113   1.064   1.029   0.767   0.677   0.623
266   F        -1.562  -1.621  -1.544  -1.218  -1.313  -1.182  -1.160  -1.186  -1.071
267   R         1.928   1.997   2.143   2.055   2.166   2.405   2.186   2.293   2.566
268   Y         1.928   1.997   2.143   2.061   2.178   2.411   2.186   2.293   2.566
269   A         0.142   0.198   0.230  -0.082   0.053   0.089  -0.146  -0.012   0.006
270   M        -0.975  -0.992  -0.887  -0.938  -0.910  -0.801  -0.957  -0.943  -0.810
271   S         0.142   0.365   0.223  -0.090   0.252   0.061  -0.146   0.180  -0.012
272   K         1.928   1.997   2.143   1.975   2.084   2.324   2.186   2.293   2.566
273   T        -0.499  -0.529  -0.442  -0.756  -0.854  -0.708  -0.653  -0.676  -0.563
274   A         1.263   1.398   1.153   1.355   1.512   1.271   1.375   1.584   1.137
275   L        -0.975  -0.895  -0.877  -1.135  -0.961  -0.992  -0.957  -0.865  -0.799
276   I         0.625   0.520   0.362   0.809   0.692   0.465   0.665   0.504   0.236
277   Q        -0.094  -0.015   0.070  -0.338  -0.312  -0.146  -0.450  -0.347  -0.241
278   C        -0.388  -0.292  -0.353  -0.387  -0.264  -0.317  -0.551  -0.448  -0.469
279   T        -0.792  -0.872  -0.829  -0.705  -0.820  -0.772  -0.754  -0.809  -0.746
280   K         0.017  -0.174  -0.268   0.223  -0.043  -0.212   0.057  -0.194  -0.326
281   M         0.142   0.070   0.144   0.248   0.134   0.244  -0.146  -0.249  -0.144
282   L         1.928   1.997   2.143   1.624   1.725   1.966   2.186   2.293   2.566
283   A         1.263   1.372   1.148   1.316   1.446   1.180   1.375   1.543   1.128
284   I        -0.571  -0.510  -0.433  -0.912  -0.767  -0.697  -0.754  -0.648  -0.552
285   K        -0.864  -0.938  -0.845  -0.717  -0.754  -0.612  -0.855  -0.888  -0.766
286   Y         0.089   0.088   0.171  -0.059  -0.026   0.066  -0.247  -0.215  -0.102
287   P         1.263   1.208   1.132   1.494   1.444   1.344   1.375   1.272   1.095
288   D        -0.571  -0.552  -0.456  -0.606  -0.573  -0.404  -0.754  -0.713  -0.581
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   V         0.310   0.364   0.258   0.255   0.362   0.122   0.158   0.261   0.055
292   L         0.310   0.155   0.178  -0.009  -0.249  -0.200   0.158  -0.093  -0.075
293   C        -0.571  -0.504  -0.439  -0.579  -0.482  -0.396  -0.754  -0.641  -0.562
294   L        -0.094   0.053   0.087  -0.363  -0.093  -0.109  -0.450  -0.236  -0.212
295   S         0.310   0.223   0.203   0.239   0.098   0.035   0.158   0.023  -0.041
296   V         0.715   0.733   0.831   0.356   0.347   0.428   0.361   0.358   0.464
297   H         1.263   1.187   1.138   1.559   1.484   1.407   1.375   1.236   1.108
298   P         1.928   1.997   2.143   2.076   2.188   2.427   2.186   2.293   2.566
299   G         1.928   1.997   2.143   1.911   2.014   2.258   2.186   2.293   2.566
300   L        -0.388  -0.479  -0.386  -0.743  -0.809  -0.666  -0.551  -0.628  -0.503
301   V         1.263   1.208   1.132   1.371   1.325   1.211   1.375   1.272   1.095
302   M         1.928   1.997   2.143   2.132   2.243   2.484   2.186   2.293   2.566
303   N         0.310   0.183   0.198   0.408   0.224   0.224   0.158  -0.044  -0.049
304   T         1.263   1.187   1.138   1.343   1.254   1.185   1.375   1.236   1.108
305   N        -0.262  -0.445  -0.401  -0.101  -0.354  -0.296  -0.349  -0.571  -0.515
306   L         1.263   1.187   1.138   1.060   0.985   0.944   1.375   1.236   1.108
307   F         0.017  -0.174  -0.268   0.273   0.025  -0.152   0.057  -0.194  -0.326
308   S        -0.262  -0.445  -0.401  -0.219  -0.471  -0.400  -0.349  -0.571  -0.515
309   Y        -0.556  -0.627  -0.753  -0.178  -0.262  -0.454  -0.450  -0.534  -0.657
310   W        -0.118  -0.235  -0.338   0.291   0.092  -0.057  -0.124  -0.293  -0.420
311   T        -0.118  -0.363  -0.375   0.070  -0.269  -0.314  -0.124  -0.446  -0.468
312   R        -0.118  -0.363  -0.375   0.110  -0.258  -0.332  -0.124  -0.446  -0.468
313   L         0.526   0.292   0.257   0.305  -0.039  -0.106   0.518   0.154   0.066
314   P         0.526   0.292   0.257   0.739   0.388   0.299   0.518   0.154   0.066
315   I        -0.465  -0.425  -0.401  -0.778  -0.714  -0.649  -0.637  -0.577  -0.517
316   V         0.212   0.092   0.150   0.152  -0.032   0.017   0.005  -0.176  -0.125
317   G         1.928   1.997   2.143   1.907   2.003   2.254   2.186   2.293   2.566
318   I         1.069   0.954   0.956   1.109   0.944   0.918   1.046   0.806   0.734
319   F         0.000   0.012   0.080  -0.384  -0.418  -0.336  -0.323  -0.315  -0.226
320   F         1.928   1.997   2.143   1.973   2.087   2.322   2.186   2.293   2.566
321   W         0.526   0.385   0.294   0.839   0.622   0.426   0.518   0.295   0.125
322   L        -0.714  -0.627  -0.787  -0.856  -0.763  -0.932  -0.637  -0.535  -0.695
323   L        -0.714  -0.886  -0.854  -0.933  -1.206  -1.140  -0.637  -0.824  -0.769
324   F         0.625   0.473   0.340   0.836   0.657   0.425   0.665   0.435   0.201
325   Q        -0.792  -0.864  -0.858  -0.595  -0.762  -0.728  -0.754  -0.828  -0.779
326   V        -0.864  -0.765  -0.815  -0.958  -0.778  -0.905  -0.855  -0.738  -0.741
327   V         0.089   0.078   0.164  -0.140  -0.130  -0.031  -0.247  -0.238  -0.116
328   G         0.017  -0.231  -0.305   0.206  -0.128  -0.237   0.057  -0.268  -0.376
329   F        -0.388  -0.444  -0.365  -0.341  -0.367  -0.265  -0.551  -0.590  -0.481
330   F        -0.792  -0.792  -0.798  -0.755  -0.759  -0.776  -0.754  -0.749  -0.720
331   F         0.310   0.147   0.174   0.289   0.009  -0.006   0.158  -0.100  -0.086
332   G         1.146   0.952   1.014   1.164   0.855   0.947   1.181   0.802   0.857
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   V         0.625   0.473   0.340   0.731   0.520   0.256   0.665   0.435   0.201
347   S         0.142   0.075   0.154  -0.051  -0.148  -0.016  -0.146  -0.239  -0.131
348   N        -0.975  -0.994  -0.901  -1.005  -1.004  -0.885  -0.957  -0.945  -0.822
349   E         0.625   0.614   0.377   0.854   0.842   0.506   0.665   0.642   0.260
350   Q        -0.388  -0.478  -0.385  -0.268  -0.390  -0.237  -0.551  -0.627  -0.501
351   G         1.928   1.997   2.143   1.911   2.014   2.258   2.186   2.293   2.566
352   S         0.310   0.444   0.272   0.289   0.499   0.255   0.158   0.380   0.078
353   L        -1.562  -1.545  -1.514  -1.301  -1.247  -1.266  -1.160  -1.129  -1.047
354   A        -0.975  -0.945  -0.883  -1.102  -1.033  -0.955  -0.957  -0.905  -0.806
355   S        -0.262  -0.264  -0.336  -0.244  -0.237  -0.360  -0.349  -0.344  -0.433
356   L         0.142   0.193   0.168  -0.308  -0.239  -0.234  -0.146  -0.102  -0.111
357   K        -0.975  -0.983  -0.889  -0.858  -0.810  -0.699  -0.957  -0.934  -0.811
358   C         0.619   0.678   0.822   0.505   0.532   0.771   0.158   0.242   0.445
359   A         0.625   0.865   0.417   0.767   1.058   0.517   0.665   1.017   0.326
360   L         0.715   0.684   0.823   0.185   0.114   0.334   0.361   0.253   0.446
361   D        -0.388  -0.456  -0.374  -0.480  -0.558  -0.439  -0.551  -0.588  -0.484
362   P        -0.262  -0.072  -0.296  -0.082   0.155  -0.134  -0.349  -0.136  -0.383
363   N        -0.920  -0.868  -0.846  -0.815  -0.735  -0.695  -0.893  -0.833  -0.769
364   L         0.526   0.292   0.257   0.323  -0.013  -0.065   0.518   0.154   0.066
365   S        -0.388  -0.476  -0.376  -0.519  -0.621  -0.464  -0.551  -0.618  -0.492
366   V        -0.975  -0.842  -0.856  -1.169  -0.983  -1.015  -0.957  -0.826  -0.781
367   E         0.017   0.048  -0.232   0.318   0.363  -0.023   0.057   0.094  -0.278
368   K        -1.673  -1.656  -1.544  -1.617  -1.627  -1.439  -1.261  -1.217  -1.073
369   D         0.625   0.447   0.357   0.838   0.587   0.403   0.665   0.394   0.228
370   N         0.625   0.547   0.352   0.834   0.753   0.425   0.665   0.546   0.220
371   G         1.263   1.217   1.130   1.322   1.275   1.162   1.375   1.287   1.092
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   K        -0.388  -0.450  -0.385  -0.500  -0.612  -0.482  -0.551  -0.601  -0.502
376   Y         0.625   0.520   0.362   0.847   0.708   0.429   0.665   0.504   0.236
377   F         0.625   0.520   0.362   0.805   0.692   0.396   0.665   0.504   0.236
378   T        -1.086  -1.143  -1.180  -0.945  -1.061  -1.138  -0.855  -0.900  -0.902
379   T         0.142   0.075   0.154   0.028  -0.071   0.060  -0.146  -0.239  -0.131
380   G        -1.269  -1.252  -1.241  -1.219  -1.188  -1.156  -1.058  -1.023  -0.961
381   G         1.263   1.208   1.132   1.314   1.248   1.146   1.375   1.272   1.095
382   K        -0.556  -0.484  -0.711  -0.311  -0.208  -0.544  -0.450  -0.362  -0.608
383   E         0.142   0.223   0.154   0.122   0.185   0.163  -0.146  -0.088  -0.129
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   S        -0.384  -0.445  -0.423  -0.532  -0.672  -0.623  -0.509  -0.594  -0.542
388   K        -1.379  -1.254  -1.236  -1.292  -1.130  -1.053  -1.160  -1.029  -0.959
389   S        -0.792  -0.887  -0.823  -0.735  -0.879  -0.832  -0.754  -0.818  -0.737
390   S         0.625   0.447   0.357   0.677   0.423   0.240   0.665   0.394   0.228
391   Y        -1.673  -1.654  -1.549  -1.515  -1.504  -1.332  -1.261  -1.215  -1.077
392   V        -1.269  -1.380  -1.253  -1.240  -1.391  -1.231  -1.058  -1.120  -0.970
393   S         0.625   0.765   0.391   0.725   0.896   0.394   0.665   0.865   0.283
394   N        -0.975  -0.980  -0.885  -0.912  -0.894  -0.761  -0.957  -0.940  -0.809
395   N         0.089   0.261   0.174  -0.012   0.263   0.152  -0.247  -0.013  -0.096
396   V        -0.975  -0.820  -0.852  -1.042  -0.744  -0.829  -0.957  -0.768  -0.771
397   D        -0.792  -0.846  -0.849  -0.657  -0.798  -0.767  -0.754  -0.812  -0.771
398   E        -1.379  -1.182  -1.232  -1.445  -1.233  -1.198  -1.160  -0.984  -0.957
399   A         1.263   1.208   1.132   1.319   1.239   1.159   1.375   1.272   1.095
400   A        -0.556  -0.795  -0.815  -0.470  -0.878  -0.955  -0.450  -0.715  -0.726
401   S        -0.571  -0.515  -0.438  -0.726  -0.596  -0.490  -0.754  -0.653  -0.558
402   T         0.142   0.120   0.140  -0.191  -0.312  -0.246  -0.146  -0.194  -0.148
403   W         1.263   1.208   1.132   1.613   1.570   1.467   1.375   1.272   1.095
404   I        -0.556  -0.795  -0.815  -0.276  -0.589  -0.631  -0.450  -0.715  -0.726
405   W         1.263   1.208   1.132   1.613   1.570   1.467   1.375   1.272   1.095
406   T         1.928   1.997   2.143   1.940   2.045   2.288   2.186   2.293   2.566
407   V        -0.792  -0.772  -0.827  -0.635  -0.625  -0.647  -0.754  -0.745  -0.747
408   H        -1.269  -1.271  -1.192  -1.064  -1.094  -0.944  -1.058  -1.026  -0.916
409   Q         0.142   0.161   0.192   0.141   0.193   0.239  -0.146  -0.083  -0.062
410   L         0.625   0.539   0.354   0.485   0.391   0.153   0.665   0.533   0.223
411   R        -0.571  -0.527  -0.431  -0.668  -0.575  -0.443  -0.754  -0.666  -0.549
412   D        -1.269  -1.240  -1.203  -1.010  -0.978  -0.907  -1.058  -1.014  -0.930
413   R        -0.556  -0.795  -0.815  -0.246  -0.604  -0.673  -0.450  -0.715  -0.726
414   G        -0.384  -0.509  -0.422  -0.428  -0.611  -0.483  -0.509  -0.651  -0.541
415   F        -1.045  -0.966  -0.900  -1.068  -0.932  -0.823  -1.022  -0.922  -0.820
416   D        -0.714  -0.691  -0.783  -0.552  -0.568  -0.724  -0.637  -0.610  -0.690
417   I         0.856   0.756   0.859   0.756   0.543   0.683   0.646   0.407   0.527
418   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
419   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
420   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
421   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
422   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
423   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
424   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08651
Output conservation file - output/Q08651
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
