1     M         1.094   1.137   1.208   1.274   1.324   1.431   1.158   1.215   1.323
2     S         0.380   0.224   0.101   0.401   0.211   0.009   0.375   0.132  -0.106
3     S        -0.957  -0.899  -0.724  -1.148  -1.042  -0.775  -1.191  -1.094  -0.855
4     I        -0.612  -0.699  -0.696  -0.623  -0.795  -0.808  -0.743  -0.878  -0.822
5     Y         0.028   0.199   0.066   0.127   0.385   0.137  -0.184   0.092  -0.167
6     K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
7     A        -1.205  -1.360  -1.208  -1.156  -1.420  -1.212  -1.191  -1.313  -1.108
8     L         0.380   0.238   0.107   0.241   0.061  -0.177   0.375   0.155  -0.094
9     A        -1.205  -1.083  -1.169  -1.149  -0.969  -1.071  -1.191  -1.029  -1.066
10    G        -1.285  -1.259  -1.201  -1.344  -1.333  -1.228  -1.302  -1.237  -1.102
11    K        -0.612  -0.787  -0.697  -0.835  -1.095  -0.949  -0.743  -0.957  -0.823
12    S        -0.941  -1.114  -1.180  -0.790  -1.051  -1.140  -0.855  -1.053  -1.077
13    K        -0.753  -0.788  -0.687  -1.073  -1.074  -0.905  -0.967  -0.961  -0.810
14    D        -0.612  -0.593  -0.647  -0.771  -0.703  -0.776  -0.743  -0.680  -0.754
15    N        -2.066  -2.050  -1.937  -1.903  -1.946  -1.740  -1.638  -1.593  -1.398
16    K        -1.862  -1.748  -1.613  -1.947  -1.769  -1.559  -1.638  -1.490  -1.285
17    S        -1.205  -1.360  -1.208  -1.310  -1.522  -1.326  -1.191  -1.313  -1.108
18    E        -1.738  -1.662  -1.604  -1.701  -1.583  -1.512  -1.526  -1.430  -1.278
19    K        -0.753  -0.614  -0.680  -1.054  -0.847  -0.853  -0.967  -0.799  -0.803
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    K        -1.956  -1.796  -1.632  -1.987  -1.698  -1.518  -1.705  -1.524  -1.300
26    Q        -1.956  -1.796  -1.632  -1.813  -1.612  -1.360  -1.705  -1.524  -1.300
27    G        -1.431  -1.405  -1.235  -1.374  -1.334  -1.106  -1.419  -1.365  -1.133
28    N         1.094   1.137   1.208   1.041   1.103   1.221   1.158   1.215   1.323
29    V        -0.707  -0.411  -0.648  -0.692  -0.252  -0.652  -0.846  -0.435  -0.755
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    K        -1.738  -1.578  -1.605  -1.727  -1.469  -1.453  -1.526  -1.354  -1.280
38    Q        -1.862  -1.665  -1.611  -1.911  -1.567  -1.530  -1.638  -1.415  -1.284
39    F        -1.862  -1.753  -1.614  -1.668  -1.547  -1.313  -1.638  -1.495  -1.286
40    M        -1.738  -1.808  -1.622  -1.494  -1.633  -1.389  -1.526  -1.534  -1.292
41    N         0.380   0.238   0.107   0.441   0.265   0.052   0.375   0.155  -0.094
42    K         0.028   0.202   0.078  -0.231   0.038  -0.153  -0.184   0.096  -0.146
43    Q         1.094   1.137   1.208   1.170   1.232   1.337   1.158   1.215   1.323
44    R         0.380   0.238   0.107   0.432   0.226  -0.013   0.375   0.155  -0.094
45    T        -0.957  -0.776  -0.695  -1.172  -0.876  -0.778  -1.191  -0.937  -0.817
46    L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
47    L        -0.957  -0.901  -0.726  -1.262  -1.137  -0.875  -1.191  -1.097  -0.857
48    I         0.028  -0.102  -0.007  -0.083  -0.352  -0.248  -0.184  -0.428  -0.301
49    S         0.028   0.120   0.029  -0.075   0.070  -0.089  -0.184  -0.039  -0.235
50    S         1.094   1.137   1.208   1.013   1.083   1.195   1.158   1.215   1.323
51    R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
52    G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
53    V         0.380   0.519   0.130   0.489   0.652   0.132   0.375   0.571  -0.053
54    N         0.028   0.238   0.081   0.029   0.339   0.071  -0.184   0.154  -0.142
55    Y         0.380   0.412   0.121   0.624   0.671   0.236   0.375   0.420  -0.069
56    R         1.094   1.137   1.208   1.077   1.125   1.253   1.158   1.215   1.323
57    H        -0.040  -0.125  -0.013   0.020  -0.152  -0.005  -0.303  -0.471  -0.312
58    R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
59    H         1.094   1.137   1.208   1.230   1.292   1.392   1.158   1.215   1.323
60    L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
61    I        -0.612  -0.624  -0.688  -0.664  -0.779  -0.834  -0.743  -0.803  -0.812
62    Q        -0.877  -0.865  -0.728  -0.968  -0.982  -0.799  -1.079  -1.056  -0.859
63    D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
64    L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
65    S        -2.518  -2.320  -2.208  -2.272  -1.987  -1.856  -1.861  -1.672  -1.477
66    G        -1.285  -1.133  -1.187  -1.300  -1.107  -1.104  -1.302  -1.128  -1.089
67    L        -0.160  -0.157  -0.012  -0.430  -0.373  -0.133  -0.520  -0.531  -0.310
68    L         0.380   0.238   0.107   0.300   0.149  -0.015   0.375   0.155  -0.094
69    P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
70    H         1.094   1.137   1.208   1.230   1.292   1.392   1.158   1.215   1.323
71    S        -1.409  -1.257  -1.205  -1.449  -1.241  -1.118  -1.414  -1.239  -1.105
72    R         0.380   0.238   0.107   0.432   0.226  -0.013   0.375   0.155  -0.094
73    K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
74    E         0.028  -0.102  -0.007  -0.075  -0.311  -0.160  -0.184  -0.428  -0.301
75    P        -0.612  -0.787  -0.697  -0.567  -0.852  -0.742  -0.743  -0.957  -0.823
76    K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
77    L        -0.160  -0.114  -0.008  -0.517  -0.436  -0.260  -0.520  -0.450  -0.303
78    D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
79    T        -0.220  -0.134  -0.007  -0.479  -0.349  -0.147  -0.631  -0.488  -0.301
80    K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
81    K        -0.612  -0.782  -0.696  -0.819  -1.057  -0.910  -0.743  -0.952  -0.822
82    D        -1.409  -1.401  -1.220  -1.557  -1.571  -1.295  -1.414  -1.358  -1.119
83    L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
84    Q        -1.205  -0.889  -1.154  -0.925  -0.474  -0.849  -1.191  -0.795  -1.050
85    Q         1.094   1.137   1.208   1.170   1.232   1.337   1.158   1.215   1.323
86    L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
87    N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
88    E         1.094   1.137   1.208   1.024   1.082   1.206   1.158   1.215   1.323
89    I        -0.877  -0.831  -0.714  -1.068  -1.057  -0.877  -1.079  -1.018  -0.843
90    A         1.094   1.137   1.208   1.102   1.156   1.276   1.158   1.215   1.323
91    E         1.094   1.137   1.208   1.024   1.082   1.206   1.158   1.215   1.323
92    L         0.380   0.412   0.121   0.300   0.363   0.004   0.375   0.420  -0.069
93    Y         1.094   1.137   1.208   1.235   1.293   1.396   1.158   1.215   1.323
94    N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
95    C         1.094   1.137   1.208   1.346   1.399   1.497   1.158   1.215   1.323
96    N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
97    N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
98    V         0.028   0.028   0.009  -0.014  -0.017  -0.090  -0.184  -0.196  -0.272
99    L        -1.409  -1.279  -1.215  -1.433  -1.225  -1.135  -1.414  -1.256  -1.115
100   F         0.380   0.412   0.121   0.525   0.571   0.182   0.375   0.420  -0.069
101   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
102   E         1.094   1.137   1.208   1.024   1.082   1.206   1.158   1.215   1.323
103   A        -0.612  -0.527  -0.669  -0.561  -0.480  -0.630  -0.743  -0.646  -0.788
104   R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
105   K         0.380   0.238   0.107   0.263   0.091  -0.103   0.375   0.155  -0.094
106   H        -0.300  -0.591  -0.653   0.019  -0.389  -0.533  -0.296  -0.679  -0.762
107   Q        -0.941  -1.189  -1.195  -0.657  -1.062  -1.101  -0.855  -1.128  -1.093
108   D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
109   L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
110   Y         1.094   1.137   1.208   1.235   1.293   1.396   1.158   1.215   1.323
111   L         0.028  -0.038   0.003  -0.156  -0.240  -0.155  -0.184  -0.312  -0.283
112   W         0.380   0.238   0.107   0.754   0.576   0.349   0.375   0.155  -0.094
113   L        -1.409  -1.363  -1.215  -1.446  -1.324  -1.135  -1.414  -1.315  -1.115
114   S         0.028  -0.030   0.008  -0.092  -0.191  -0.153  -0.184  -0.299  -0.273
115   K         0.380   0.238   0.107   0.263   0.091  -0.103   0.375   0.155  -0.094
116   P        -0.612  -0.787  -0.697  -0.534  -0.813  -0.691  -0.743  -0.957  -0.823
117   P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
118   N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
119   G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
120   P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
121   T         1.094   1.137   1.208   1.154   1.202   1.323   1.158   1.215   1.323
122   I        -1.409  -1.319  -1.218  -1.541  -1.375  -1.237  -1.414  -1.284  -1.118
123   K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
124   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
125   Y        -0.160   0.012   0.034  -0.156   0.129   0.126  -0.520  -0.224  -0.226
126   I        -1.205  -1.241  -1.194  -1.168  -1.229  -1.186  -1.191  -1.213  -1.095
127   Q         0.380   0.238   0.107   0.547   0.361   0.123   0.375   0.155  -0.094
128   N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
129   L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
130   H         1.094   1.137   1.208   1.230   1.292   1.392   1.158   1.215   1.323
131   T         1.094   1.137   1.208   1.154   1.202   1.323   1.158   1.215   1.323
132   M         0.028   0.202   0.078   0.094   0.369   0.098  -0.184   0.096  -0.146
133   D         0.380   0.224   0.101   0.495   0.282   0.066   0.375   0.132  -0.106
134   E         1.094   1.137   1.208   1.024   1.082   1.206   1.158   1.215   1.323
135   L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
136   N         0.380   0.224   0.101   0.461   0.275   0.095   0.375   0.132  -0.106
137   F         0.380   0.238   0.107   0.531   0.359   0.176   0.375   0.155  -0.094
138   T         1.094   1.137   1.208   1.154   1.202   1.323   1.158   1.215   1.323
139   G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
140   N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
141   C         0.380   0.238   0.107   0.733   0.542   0.299   0.375   0.155  -0.094
142   L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
143   K         0.380   0.412   0.121   0.263   0.321  -0.081   0.375   0.420  -0.069
144   G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
145   S         1.094   1.137   1.208   1.013   1.083   1.195   1.158   1.215   1.323
146   R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
147   P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
148   V        -0.300  -0.299  -0.615  -0.156  -0.183  -0.666  -0.296  -0.315  -0.711
149   L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
150   S         1.094   1.137   1.208   1.013   1.083   1.195   1.158   1.215   1.323
151   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
152   D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
153   Q        -2.066  -1.902  -1.925  -2.059  -1.871  -1.842  -1.638  -1.468  -1.390
154   R        -1.285  -1.393  -1.214  -1.335  -1.448  -1.176  -1.302  -1.351  -1.114
155   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
156   E        -0.753  -0.622  -0.673  -0.910  -0.727  -0.796  -0.967  -0.801  -0.796
157   S        -2.190  -2.072  -1.931  -2.008  -1.815  -1.628  -1.750  -1.608  -1.394
158   S        -1.738  -1.641  -1.592  -1.633  -1.537  -1.449  -1.526  -1.415  -1.269
159   P         0.028   0.202   0.078   0.041   0.304   0.086  -0.184   0.096  -0.146
160   H         1.094   1.137   1.208   1.230   1.292   1.392   1.158   1.215   1.323
161   Y        -0.941  -0.955  -1.151  -0.596  -0.659  -0.979  -0.855  -0.869  -1.046
162   Q        -1.409  -1.304  -1.210  -1.574  -1.425  -1.238  -1.414  -1.269  -1.110
163   L        -0.160  -0.157  -0.012  -0.526  -0.507  -0.257  -0.520  -0.531  -0.310
164   I        -0.612  -0.610  -0.653  -0.664  -0.606  -0.742  -0.743  -0.704  -0.762
165   K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
166   E         1.094   1.137   1.208   1.024   1.082   1.206   1.158   1.215   1.323
167   L        -0.753  -0.797  -0.680  -0.897  -0.935  -0.732  -0.967  -0.972  -0.804
168   L        -0.753  -0.620  -0.675  -0.913  -0.758  -0.743  -0.967  -0.809  -0.798
169   V        -1.862  -1.754  -1.610  -1.863  -1.717  -1.482  -1.638  -1.502  -1.283
170   H        -0.220  -0.110   0.004  -0.312  -0.132   0.026  -0.631  -0.444  -0.281
171   N        -0.753  -0.761  -0.682  -0.783  -0.730  -0.612  -0.967  -0.918  -0.802
172   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
173   G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
174   V         0.380   0.238   0.107   0.489   0.298   0.092   0.375   0.155  -0.094
175   P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
176   P        -0.612  -0.787  -0.697  -0.603  -0.895  -0.791  -0.743  -0.957  -0.823
177   N        -1.285  -1.037  -1.181  -1.227  -0.870  -1.021  -1.302  -1.008  -1.081
178   A         0.380   0.539   0.131   0.478   0.672   0.104   0.375   0.599  -0.052
179   R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
180   K         0.380   0.238   0.107   0.263   0.091  -0.103   0.375   0.155  -0.094
181   S         0.380   0.539   0.131   0.397   0.604   0.050   0.375   0.599  -0.052
182   K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
183   P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
184   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
185   I        -0.300  -0.158  -0.592  -0.119   0.073  -0.540  -0.296  -0.106  -0.679
186   D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
187   H         0.380   0.238   0.107   0.614   0.430   0.192   0.375   0.155  -0.094
188   V         0.380   0.516   0.128   0.489   0.649   0.127   0.375   0.567  -0.058
189   M        -0.300  -0.432  -0.624   0.099  -0.070  -0.365  -0.296  -0.470  -0.723
190   S        -0.220  -0.156  -0.015  -0.479  -0.376  -0.153  -0.631  -0.529  -0.316
191   F         0.380   0.238   0.107   0.476   0.278   0.027   0.375   0.155  -0.094
192   S         0.380   0.238   0.107   0.409   0.242   0.041   0.375   0.155  -0.094
193   I         0.380   0.412   0.121   0.451   0.511   0.032   0.375   0.420  -0.069
194   V         0.028  -0.102  -0.007  -0.005  -0.261  -0.114  -0.184  -0.428  -0.301
195   D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
196   D        -1.409  -1.174  -1.191  -1.415  -1.053  -1.100  -1.414  -1.128  -1.091
197   K         1.094   1.137   1.208   0.879   0.950   1.074   1.158   1.215   1.323
198   I         0.380   0.412   0.121   0.481   0.539   0.112   0.375   0.420  -0.069
199   W         1.094   1.137   1.208   1.351   1.404   1.500   1.158   1.215   1.323
200   V        -0.877  -0.801  -0.704  -0.965  -0.867  -0.724  -1.079  -0.974  -0.831
201   R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
202   T        -0.160   0.012   0.034  -0.350  -0.069  -0.049  -0.520  -0.224  -0.226
203   Y         1.094   1.137   1.208   1.235   1.293   1.396   1.158   1.215   1.323
204   E        -0.160  -0.049   0.013  -0.368  -0.190  -0.099  -0.520  -0.333  -0.265
205   I         1.094   1.137   1.208   1.093   1.164   1.268   1.158   1.215   1.323
206   S        -1.409  -1.319  -1.218  -1.514  -1.358  -1.192  -1.414  -1.284  -1.118
207   H        -0.160   0.012   0.034  -0.335  -0.066  -0.034  -0.520  -0.224  -0.226
208   S        -1.738  -1.746  -1.611  -1.636  -1.649  -1.473  -1.526  -1.486  -1.284
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   T        -1.843  -1.578  -1.609  -1.810  -1.453  -1.467  -1.617  -1.337  -1.282
212   K        -0.877  -0.803  -0.706  -1.209  -1.104  -0.936  -1.079  -0.976  -0.832
213   N        -1.205  -1.239  -1.201  -1.165  -1.228  -1.160  -1.191  -1.211  -1.101
214   K        -1.205  -0.994  -1.165  -1.328  -1.009  -1.218  -1.191  -0.921  -1.064
215   E        -2.066  -1.915  -1.910  -1.872  -1.666  -1.659  -1.638  -1.478  -1.379
216   E         0.028   0.014   0.012  -0.153  -0.197  -0.257  -0.184  -0.221  -0.266
217   Y        -1.261  -1.275  -1.226  -1.189  -1.319  -1.294  -1.228  -1.238  -1.124
218   E        -0.550  -0.676  -0.692  -0.538  -0.747  -0.774  -0.631  -0.820  -0.813
219   D        -1.261  -1.258  -1.215  -1.183  -1.233  -1.173  -1.228  -1.222  -1.113
220   G        -1.426  -1.238  -1.214  -1.532  -1.263  -1.243  -1.427  -1.193  -1.112
221   E         0.240  -0.000   0.034   0.241  -0.123  -0.070   0.164  -0.246  -0.226
222   E        -0.707  -0.824  -0.717  -0.781  -0.984  -0.817  -0.846  -1.002  -0.845
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -0.550  -0.367  -0.618  -0.455  -0.196  -0.587  -0.631  -0.378  -0.714
230   D        -1.702  -1.714  -1.609  -1.558  -1.621  -1.479  -1.471  -1.456  -1.281
231   I        -1.738  -1.759  -1.611  -1.733  -1.748  -1.531  -1.526  -1.498  -1.283
232   S        -0.300  -0.338  -0.612  -0.200  -0.245  -0.640  -0.296  -0.355  -0.706
233   L         0.380   0.224   0.101   0.261   0.071  -0.135   0.375   0.132  -0.106
234   V        -0.300  -0.591  -0.653  -0.150  -0.588  -0.736  -0.296  -0.679  -0.762
235   E         0.380   0.224   0.101   0.381   0.161  -0.070   0.375   0.132  -0.106
236   I         0.380   0.224   0.101   0.477   0.283   0.065   0.375   0.132  -0.106
237   G         0.380   0.224   0.101   0.518   0.288   0.047   0.375   0.132  -0.106
238   P         0.380   0.224   0.101   0.541   0.344   0.142   0.375   0.132  -0.106
239   R         0.380   0.224   0.101   0.463   0.252   0.061   0.375   0.132  -0.106
240   F        -0.300  -0.351  -0.619  -0.124  -0.195  -0.635  -0.296  -0.374  -0.716
241   V         0.380   0.224   0.101   0.483   0.266   0.065   0.375   0.132  -0.106
242   M        -0.612  -0.621  -0.655  -0.490  -0.470  -0.608  -0.743  -0.719  -0.765
243   T         0.380   0.224   0.101   0.531   0.311   0.097   0.375   0.132  -0.106
244   V        -1.205  -1.104  -1.177  -1.300  -1.133  -1.206  -1.191  -1.041  -1.074
245   I         0.380   0.224   0.101   0.450   0.243  -0.011   0.375   0.132  -0.106
246   L        -1.285  -1.393  -1.214  -1.387  -1.492  -1.225  -1.302  -1.351  -1.114
247   I        -1.205  -1.213  -1.182  -1.069  -1.051  -1.004  -1.191  -1.156  -1.081
248   L         0.380   0.224   0.101   0.277   0.093  -0.091   0.375   0.132  -0.106
249   E         1.094   1.137   1.208   1.024   1.082   1.206   1.158   1.215   1.323
250   G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
251   S         0.028   0.013   0.006  -0.092  -0.117  -0.156  -0.184  -0.222  -0.276
252   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
253   G         0.380   0.519   0.130   0.536   0.703   0.153   0.375   0.571  -0.053
254   G         1.094   1.137   1.208   1.161   1.209   1.329   1.158   1.215   1.323
255   P         1.094   1.137   1.208   1.145   1.207   1.315   1.158   1.215   1.323
256   K        -0.612  -0.787  -0.697  -0.788  -1.028  -0.866  -0.743  -0.957  -0.823
257   I         1.094   1.137   1.208   1.093   1.164   1.268   1.158   1.215   1.323
258   Y         0.380   0.412   0.121   0.624   0.671   0.236   0.375   0.420  -0.069
259   E         0.380   0.238   0.107   0.381   0.183  -0.057   0.375   0.155  -0.094
260   N         1.094   1.137   1.208   1.054   1.116   1.233   1.158   1.215   1.323
261   K        -0.300  -0.340  -0.614  -0.337  -0.387  -0.755  -0.296  -0.359  -0.709
262   Q        -0.941  -1.096  -1.175  -0.644  -0.892  -1.038  -0.855  -1.036  -1.071
263   Y         0.028  -0.102  -0.007   0.127  -0.126  -0.010  -0.184  -0.428  -0.301
264   V         0.380   0.224   0.101   0.489   0.278   0.080   0.375   0.132  -0.106
265   S         1.094   1.137   1.208   1.013   1.083   1.195   1.158   1.215   1.323
266   P         0.380   0.238   0.107   0.521   0.336   0.098   0.375   0.155  -0.094
267   N         0.380   0.238   0.107   0.450   0.274   0.076   0.375   0.155  -0.094
268   V        -2.066  -2.039  -1.936  -1.683  -1.651  -1.507  -1.638  -1.585  -1.397
269   V         1.094   1.137   1.208   1.102   1.149   1.276   1.158   1.215   1.323
270   R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
271   A        -0.160  -0.137  -0.015  -0.383  -0.368  -0.187  -0.520  -0.494  -0.316
272   Q        -0.300  -0.591  -0.653  -0.058  -0.474  -0.621  -0.296  -0.679  -0.762
273   I        -0.957  -0.865  -0.724  -1.183  -1.040  -0.803  -1.191  -1.056  -0.855
274   K         0.028  -0.102  -0.007  -0.231  -0.454  -0.291  -0.184  -0.428  -0.301
275   Q        -0.300  -0.591  -0.653  -0.089  -0.522  -0.699  -0.296  -0.679  -0.762
276   Q         0.380   0.224   0.101   0.558   0.357   0.140   0.375   0.132  -0.106
277   A         0.380   0.224   0.101   0.459   0.235  -0.003   0.375   0.132  -0.106
278   A         1.094   1.137   1.208   1.102   1.156   1.276   1.158   1.215   1.323
279   E        -2.190  -2.125  -1.941  -2.076  -1.954  -1.729  -1.750  -1.648  -1.401
280   E        -0.957  -0.903  -0.727  -1.130  -1.052  -0.782  -1.191  -1.100  -0.859
281   A        -0.300  -0.591  -0.653  -0.069  -0.445  -0.534  -0.296  -0.679  -0.762
282   K        -0.941  -1.189  -1.195  -0.931  -1.283  -1.269  -0.855  -1.128  -1.093
283   S        -0.612  -0.757  -0.688  -0.648  -0.853  -0.751  -0.743  -0.914  -0.812
284   R         1.094   1.137   1.208   1.075   1.125   1.251   1.158   1.215   1.323
285   A        -0.941  -1.112  -1.178  -0.704  -0.963  -1.079  -0.855  -1.051  -1.075
286   E        -0.941  -0.612  -1.119  -0.778  -0.352  -1.038  -0.855  -0.454  -1.012
287   A        -0.300  -0.591  -0.653  -0.116  -0.522  -0.649  -0.296  -0.679  -0.762
288   A        -0.300  -0.591  -0.653  -0.148  -0.584  -0.732  -0.296  -0.679  -0.762
289   V        -1.285  -1.308  -1.207  -1.470  -1.516  -1.340  -1.302  -1.273  -1.106
290   E         0.380   0.412   0.121   0.381   0.427  -0.030   0.375   0.420  -0.069
291   R         0.380   0.540   0.136   0.432   0.628   0.041   0.375   0.600  -0.044
292   K        -0.300  -0.591  -0.653  -0.360  -0.759  -0.873  -0.296  -0.679  -0.762
293   I        -1.409  -1.407  -1.221  -1.525  -1.477  -1.229  -1.414  -1.364  -1.120
294   K         0.380   0.238   0.107   0.263   0.091  -0.103   0.375   0.155  -0.094
295   R        -1.738  -1.797  -1.608  -1.862  -1.951  -1.642  -1.526  -1.524  -1.281
296   R        -0.300  -0.591  -0.653  -0.141  -0.554  -0.665  -0.296  -0.679  -0.762
297   E        -1.738  -1.776  -1.615  -1.631  -1.662  -1.420  -1.526  -1.515  -1.287
298   N        -1.862  -1.787  -1.609  -1.860  -1.780  -1.523  -1.638  -1.524  -1.283
299   V         0.380   0.224   0.101   0.498   0.287   0.104   0.375   0.132  -0.106
300   L        -0.612  -0.787  -0.697  -0.783  -1.013  -0.864  -0.743  -0.957  -0.823
301   A        -1.205  -1.321  -1.205  -1.186  -1.306  -1.171  -1.191  -1.268  -1.104
302   A        -0.941  -0.871  -1.138  -0.758  -0.690  -1.118  -0.855  -0.776  -1.033
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   D         1.094   1.137   1.208   1.118   1.173   1.290   1.158   1.215   1.323
308   P         0.380   0.224   0.101   0.533   0.331   0.120   0.375   0.132  -0.106
309   L         1.094   1.137   1.208   0.886   0.960   1.081   1.158   1.215   1.323
310   S        -0.877  -0.865  -0.728  -1.038  -1.019  -0.809  -1.079  -1.056  -0.859
311   N        -0.300  -0.445  -0.633  -0.148  -0.340  -0.616  -0.296  -0.488  -0.734
312   D        -1.093  -1.196  -1.205  -0.932  -1.129  -1.179  -1.033  -1.151  -1.103
313   A        -1.326  -1.334  -1.214  -1.339  -1.387  -1.196  -1.325  -1.306  -1.114
314   L        -0.300  -0.432  -0.624  -0.329  -0.491  -0.765  -0.296  -0.470  -0.723
315   F         1.094   1.137   1.208   1.118   1.175   1.290   1.158   1.215   1.323
316   K         0.028  -0.102  -0.007  -0.222  -0.437  -0.274  -0.184  -0.428  -0.301
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08235
Output conservation file - output/Q08235
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
