1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    M         0.131  -0.022  -0.003   0.244  -0.071  -0.068   0.033  -0.211  -0.189
38    F        -0.931  -0.930  -0.925  -1.038  -1.033  -1.062  -0.932  -0.906  -0.885
39    T        -1.702  -1.602  -1.583  -1.451  -1.307  -1.258  -1.415  -1.266  -1.230
40    R         0.131  -0.022  -0.003   0.298   0.030   0.052   0.033  -0.211  -0.189
41    R        -1.702  -1.602  -1.583  -1.424  -1.232  -1.231  -1.415  -1.266  -1.230
42    F        -0.931  -0.955  -0.933  -0.964  -0.973  -0.988  -0.932  -0.932  -0.895
43    I         0.131   0.240   0.055   0.021   0.206  -0.143   0.033   0.205  -0.094
44    P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
45    V        -0.931  -0.930  -0.925  -1.112  -1.173  -1.128  -0.932  -0.906  -0.885
46    V        -1.702  -1.602  -1.583  -1.810  -1.613  -1.605  -1.415  -1.266  -1.230
47    Q        -1.062  -0.987  -0.954  -0.935  -0.825  -0.757  -1.093  -0.964  -0.919
48    S        -1.062  -0.987  -0.954  -1.167  -1.030  -0.983  -1.093  -0.964  -0.919
49    T        -1.062  -0.987  -0.954  -1.013  -0.849  -0.833  -1.093  -0.964  -0.919
50    K        -0.931  -0.930  -0.925  -1.144  -1.093  -1.141  -0.932  -0.906  -0.885
51    Q         0.131   0.290   0.068   0.098   0.333   0.022   0.033   0.282  -0.072
52    N        -0.931  -0.955  -0.933  -1.089  -1.114  -1.124  -0.932  -0.932  -0.895
53    I        -1.702  -1.602  -1.583  -1.511  -1.313  -1.316  -1.415  -1.266  -1.230
54    G        -0.931  -0.930  -0.925  -0.778  -0.802  -0.757  -0.932  -0.906  -0.885
55    K         0.131  -0.022  -0.003   0.128  -0.071  -0.034   0.033  -0.211  -0.189
56    Y        -1.702  -1.602  -1.583  -1.477  -1.298  -1.283  -1.415  -1.266  -1.230
57    V        -1.702  -1.602  -1.583  -1.824  -1.573  -1.619  -1.415  -1.266  -1.230
58    R        -1.062  -0.999  -0.954  -1.056  -0.952  -0.875  -1.093  -0.979  -0.919
59    K        -0.034  -0.072  -0.036  -0.240  -0.303  -0.245  -0.235  -0.295  -0.246
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    D        -1.062  -0.999  -0.954  -1.239  -1.134  -1.052  -1.093  -0.979  -0.919
71    A        -1.062  -0.999  -0.954  -0.918  -0.797  -0.741  -1.093  -0.979  -0.919
72    R        -0.034  -0.072  -0.036  -0.040  -0.132  -0.085  -0.235  -0.295  -0.246
73    F         0.131  -0.022  -0.003   0.185  -0.091  -0.050   0.033  -0.211  -0.189
74    T         0.131  -0.022  -0.003   0.209  -0.046  -0.023   0.033  -0.211  -0.189
75    L        -0.931  -0.955  -0.933  -1.140  -1.143  -1.070  -0.932  -0.932  -0.895
76    L         0.131  -0.022  -0.003  -0.101  -0.279  -0.244   0.033  -0.211  -0.189
77    T        -0.160  -0.096  -0.056  -0.308  -0.199  -0.135  -0.449  -0.336  -0.279
78    Y         0.131  -0.022  -0.003   0.156  -0.093  -0.059   0.033  -0.211  -0.189
79    N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
80    M        -0.160  -0.096  -0.056  -0.438  -0.362  -0.292  -0.449  -0.336  -0.279
81    L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
82    S         1.382   1.434   1.451   1.388   1.464   1.494   1.481   1.542   1.570
83    P         0.131  -0.022  -0.003   0.309   0.071   0.102   0.033  -0.211  -0.189
84    S        -0.931  -0.955  -0.933  -0.874  -0.889  -0.860  -0.932  -0.932  -0.895
85    Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
86    M         1.382   1.434   1.451   1.589   1.664   1.689   1.481   1.542   1.570
87    W         1.382   1.434   1.451   1.636   1.708   1.735   1.481   1.542   1.570
88    P         0.131  -0.022  -0.003   0.226  -0.056  -0.033   0.033  -0.211  -0.189
89    Q         0.131  -0.022  -0.003   0.337   0.093   0.116   0.033  -0.211  -0.189
90    V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
91    Y         0.131  -0.022  -0.003   0.156  -0.093  -0.059   0.033  -0.211  -0.189
92    T         0.131  -0.022  -0.003   0.233  -0.006   0.017   0.033  -0.211  -0.189
93    Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
94    V         0.131  -0.022  -0.003   0.017  -0.289  -0.272   0.033  -0.211  -0.189
95    A        -1.702  -1.602  -1.583  -1.490  -1.333  -1.295  -1.415  -1.266  -1.230
96    E        -0.931  -0.955  -0.933  -0.820  -0.831  -0.815  -0.932  -0.932  -0.895
97    P        -0.931  -0.733  -0.879  -0.881  -0.552  -0.795  -0.932  -0.651  -0.829
98    Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
99    K         0.131  -0.022  -0.003  -0.062  -0.356  -0.342   0.033  -0.211  -0.189
100   N        -0.931  -0.928  -0.923  -0.946  -0.944  -0.930  -0.932  -0.904  -0.883
101   W         1.382   1.434   1.451   1.636   1.708   1.735   1.481   1.542   1.570
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   S        -0.931  -0.733  -0.879  -0.946  -0.618  -0.856  -0.932  -0.651  -0.829
104   Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
105   R         1.382   1.434   1.451   1.545   1.620   1.647   1.481   1.542   1.570
106   H         0.131  -0.022  -0.003   0.304   0.030   0.071   0.033  -0.211  -0.189
107   R        -0.931  -0.930  -0.925  -0.795  -0.787  -0.803  -0.932  -0.906  -0.885
108   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
109   L         0.131  -0.022  -0.003  -0.180  -0.401  -0.372   0.033  -0.211  -0.189
110   E         1.382   1.434   1.451   1.445   1.520   1.549   1.481   1.542   1.570
111   K        -1.702  -1.602  -1.583  -1.544  -1.393  -1.348  -1.415  -1.266  -1.230
112   E         0.131  -0.022  -0.003   0.102  -0.204  -0.195   0.033  -0.211  -0.189
113   L         0.131  -0.022  -0.003  -0.101  -0.279  -0.244   0.033  -0.211  -0.189
114   L        -0.931  -0.955  -0.933  -1.213  -1.215  -1.158  -0.932  -0.932  -0.895
115   N        -1.702  -1.602  -1.583  -1.575  -1.365  -1.378  -1.415  -1.266  -1.230
116   T        -0.931  -0.928  -0.923  -0.930  -0.888  -0.881  -0.932  -0.904  -0.883
117   F        -0.160  -0.097  -0.055  -0.326  -0.221  -0.143  -0.449  -0.337  -0.278
118   K        -0.931  -0.930  -0.925  -0.962  -0.967  -0.921  -0.932  -0.906  -0.885
119   A        -0.931  -0.955  -0.933  -0.637  -0.655  -0.646  -0.932  -0.932  -0.895
120   D         1.382   1.434   1.451   1.380   1.457   1.486   1.481   1.542   1.570
121   I         1.382   1.434   1.451   1.363   1.437   1.470   1.481   1.542   1.570
122   M         0.131   0.240   0.055   0.336   0.509   0.193   0.033   0.205  -0.094
123   C         1.382   1.434   1.451   1.648   1.716   1.746   1.481   1.542   1.570
124   L         0.131  -0.022  -0.003  -0.156  -0.373  -0.333   0.033  -0.211  -0.189
125   Q         1.382   1.434   1.451   1.545   1.623   1.647   1.481   1.542   1.570
126   E         1.382   1.434   1.451   1.445   1.520   1.549   1.481   1.542   1.570
127   M        -0.160  -0.097  -0.055  -0.438  -0.265  -0.217  -0.449  -0.337  -0.278
128   T         0.131  -0.022  -0.003   0.227  -0.019   0.006   0.033  -0.211  -0.189
129   A        -1.702  -1.602  -1.583  -1.416  -1.248  -1.223  -1.415  -1.266  -1.230
130   R        -1.702  -1.602  -1.583  -1.712  -1.620  -1.510  -1.415  -1.266  -1.230
131   D         0.131  -0.022  -0.003   0.134  -0.122  -0.095   0.033  -0.211  -0.189
132   Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
133   E        -0.931  -0.771  -0.876  -0.889  -0.619  -0.800  -0.932  -0.699  -0.826
134   D        -1.702  -1.602  -1.583  -1.686  -1.534  -1.485  -1.415  -1.266  -1.230
135   Y         0.131   0.290   0.068   0.190   0.419   0.085   0.033   0.282  -0.072
136   W         1.382   1.434   1.451   1.636   1.708   1.735   1.481   1.542   1.570
137   H        -0.931  -0.928  -0.923  -0.962  -0.963  -0.919  -0.932  -0.904  -0.883
138   D         0.131   0.290   0.068   0.043   0.289  -0.052   0.033   0.282  -0.072
139   S        -1.702  -1.602  -1.583  -1.401  -1.239  -1.209  -1.415  -1.266  -1.230
140   I        -1.702  -1.602  -1.583  -1.700  -1.500  -1.499  -1.415  -1.266  -1.230
141   G        -1.702  -1.602  -1.583  -1.354  -1.194  -1.163  -1.415  -1.266  -1.230
142   V        -1.702  -1.602  -1.583  -1.635  -1.465  -1.436  -1.415  -1.266  -1.230
143   D        -1.702  -1.602  -1.583  -1.509  -1.325  -1.314  -1.415  -1.266  -1.230
144   V        -0.034   0.039  -0.035   0.053   0.180   0.018  -0.235  -0.111  -0.243
145   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
146   Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
147   G         0.131  -0.022  -0.003   0.271   0.037   0.065   0.033  -0.211  -0.189
148   S         1.382   1.434   1.451   1.388   1.464   1.494   1.481   1.542   1.570
149   K        -0.931  -0.928  -0.923  -0.971  -0.967  -0.959  -0.932  -0.904  -0.883
150   F        -0.160  -0.096  -0.056  -0.326  -0.226  -0.151  -0.449  -0.336  -0.279
151   I        -0.931  -0.955  -0.933  -0.940  -0.987  -0.934  -0.932  -0.932  -0.895
152   S        -0.931  -0.928  -0.923  -0.680  -0.671  -0.680  -0.932  -0.904  -0.883
153   K         1.382   1.434   1.451   1.280   1.359   1.390   1.481   1.542   1.570
154   T         0.131  -0.022  -0.003   0.106  -0.199  -0.191   0.033  -0.211  -0.189
155   P         0.131  -0.022  -0.003   0.277   0.022   0.050   0.033  -0.211  -0.189
156   P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
157   K        -0.931  -0.930  -0.925  -0.969  -0.976  -0.930  -0.932  -0.906  -0.885
158   Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
159   W         1.382   1.434   1.451   1.636   1.708   1.735   1.481   1.542   1.570
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   K        -0.931  -0.955  -0.933  -1.003  -1.029  -0.981  -0.932  -0.932  -0.895
162   K        -0.160  -0.096  -0.056  -0.314  -0.174  -0.118  -0.449  -0.336  -0.279
163   P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
164   V        -0.931  -0.955  -0.933  -1.101  -1.124  -1.132  -0.932  -0.932  -0.895
165   K         0.131   0.290   0.068   0.171   0.423   0.054   0.033   0.282  -0.072
166   D        -1.702  -1.602  -1.583  -1.430  -1.295  -1.237  -1.415  -1.266  -1.230
167   M         0.131  -0.022  -0.003   0.336   0.065   0.083   0.033  -0.211  -0.189
168   D         1.382   1.434   1.451   1.380   1.457   1.486   1.481   1.542   1.570
169   G         1.382   1.434   1.451   1.465   1.546   1.569   1.481   1.542   1.570
170   V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
171   S         0.131   0.290   0.068   0.224   0.475   0.118   0.033   0.282  -0.072
172   I         1.382   1.434   1.451   1.363   1.437   1.470   1.481   1.542   1.570
173   F         1.382   1.434   1.451   1.433   1.491   1.538   1.481   1.542   1.570
174   Y         0.131  -0.022  -0.003   0.132  -0.124  -0.097   0.033  -0.211  -0.189
175   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
176   L         0.131  -0.022  -0.003  -0.145  -0.343  -0.314   0.033  -0.211  -0.189
177   A         0.131   0.290   0.068   0.214   0.444   0.138   0.033   0.282  -0.072
178   K         1.382   1.434   1.451   1.280   1.359   1.390   1.481   1.542   1.570
179   F         1.382   1.434   1.451   1.433   1.491   1.538   1.481   1.542   1.570
180   D        -0.160  -0.097  -0.055  -0.317  -0.210  -0.143  -0.449  -0.337  -0.278
181   F        -0.931  -0.955  -0.933  -0.910  -0.974  -0.922  -0.932  -0.932  -0.895
182   I        -0.160  -0.085  -0.049  -0.613  -0.500  -0.439  -0.449  -0.317  -0.268
183   S        -0.931  -0.955  -0.933  -0.917  -0.964  -0.914  -0.932  -0.932  -0.895
184   S         0.131   0.287   0.066   0.201   0.430   0.115   0.033   0.276  -0.075
185   S         0.131  -0.022  -0.003   0.197  -0.036   0.001   0.033  -0.211  -0.189
186   G        -0.931  -0.955  -0.933  -0.773  -0.773  -0.763  -0.932  -0.932  -0.895
187   I         0.131   0.240   0.055   0.021   0.206  -0.143   0.033   0.205  -0.094
188   Y         0.131  -0.022  -0.003   0.189  -0.041  -0.006   0.033  -0.211  -0.189
189   L         0.131  -0.022  -0.003  -0.156  -0.373  -0.333   0.033  -0.211  -0.189
190   N         0.131  -0.022  -0.003   0.163  -0.076  -0.045   0.033  -0.211  -0.189
191   Q        -0.931  -0.955  -0.933  -0.778  -0.820  -0.798  -0.932  -0.932  -0.895
192   L         0.131  -0.022  -0.003  -0.175  -0.390  -0.363   0.033  -0.211  -0.189
193   L        -0.931  -0.955  -0.933  -1.248  -1.242  -1.201  -0.932  -0.932  -0.895
194   N        -0.034   0.039  -0.035  -0.066   0.059  -0.084  -0.235  -0.111  -0.243
195   V        -0.034  -0.023  -0.045  -0.110  -0.089  -0.129  -0.235  -0.213  -0.260
196   F         1.382   1.434   1.451   1.472   1.547   1.575   1.481   1.542   1.570
197   N        -1.062  -1.019  -0.954  -1.153  -1.070  -0.969  -1.093  -1.002  -0.919
198   Q        -0.034   0.022  -0.036   0.017   0.115  -0.015  -0.235  -0.138  -0.246
199   R        -1.062  -1.019  -0.954  -0.964  -0.880  -0.786  -1.093  -1.002  -0.919
200   E         1.382   1.434   1.451   1.445   1.520   1.549   1.481   1.542   1.570
201   L         0.131  -0.022  -0.003  -0.101  -0.279  -0.244   0.033  -0.211  -0.189
202   K        -1.702  -1.602  -1.583  -1.507  -1.308  -1.312  -1.415  -1.266  -1.230
203   Y         0.131  -0.022  -0.003   0.189  -0.041  -0.006   0.033  -0.211  -0.189
204   L         0.131  -0.022  -0.003  -0.121  -0.316  -0.276   0.033  -0.211  -0.189
205   Y        -1.702  -1.602  -1.583  -1.602  -1.443  -1.403  -1.415  -1.266  -1.230
206   N        -0.931  -0.768  -0.880  -0.967  -0.714  -0.867  -0.932  -0.696  -0.831
207   K        -0.931  -0.955  -0.933  -0.942  -0.977  -0.907  -0.932  -0.932  -0.895
208   K        -0.931  -0.733  -0.879  -0.940  -0.620  -0.850  -0.932  -0.651  -0.829
209   V         0.131   0.240   0.055   0.114   0.281  -0.011   0.033   0.205  -0.094
210   T         1.382   1.434   1.451   1.449   1.526   1.553   1.481   1.542   1.570
211   L         1.382   1.434   1.451   1.022   1.098   1.139   1.481   1.542   1.570
212   T         1.382   1.434   1.451   1.450   1.526   1.555   1.481   1.542   1.570
213   D        -0.034  -0.023  -0.045  -0.135  -0.118  -0.164  -0.235  -0.213  -0.260
214   G         1.382   1.434   1.451   1.450   1.525   1.555   1.481   1.542   1.570
215   A         1.382   1.434   1.451   1.614   1.690   1.713   1.481   1.542   1.570
216   S        -0.034   0.039  -0.035  -0.058   0.066  -0.075  -0.235  -0.111  -0.243
217   N        -0.034  -0.023  -0.045  -0.130  -0.113  -0.162  -0.235  -0.213  -0.260
218   V        -0.034   0.022  -0.036  -0.068   0.028  -0.063  -0.235  -0.138  -0.246
219   I        -0.034   0.022  -0.036  -0.147  -0.051  -0.163  -0.235  -0.138  -0.246
220   G         1.382   1.434   1.451   1.450   1.525   1.555   1.481   1.542   1.570
221   E         1.382   1.434   1.451   1.445   1.520   1.549   1.481   1.542   1.570
222   D        -0.931  -0.930  -0.925  -0.917  -0.946  -0.899  -0.932  -0.906  -0.885
223   S         0.131  -0.022  -0.003   0.222   0.007   0.041   0.033  -0.211  -0.189
224   L         0.131  -0.022  -0.003  -0.150  -0.354  -0.323   0.033  -0.211  -0.189
225   L        -0.931  -0.955  -0.933  -1.240  -1.235  -1.192  -0.932  -0.932  -0.895
226   D        -1.702  -1.602  -1.583  -1.540  -1.368  -1.343  -1.415  -1.266  -1.230
227   V        -0.931  -0.930  -0.925  -0.900  -0.871  -0.871  -0.932  -0.906  -0.885
228   L        -0.931  -0.955  -0.933  -1.131  -1.135  -1.058  -0.932  -0.932  -0.895
229   K         0.131  -0.022  -0.003   0.037  -0.210  -0.180   0.033  -0.211  -0.189
230   G        -1.702  -1.602  -1.583  -1.424  -1.252  -1.231  -1.415  -1.266  -1.230
231   K        -0.160  -0.085  -0.049  -0.314  -0.148  -0.101  -0.449  -0.317  -0.268
232   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
233   Q         0.131  -0.022  -0.003   0.321   0.071   0.089   0.033  -0.211  -0.189
234   V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
235   C        -0.160  -0.096  -0.056  -0.009   0.092   0.155  -0.449  -0.336  -0.279
236   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
237   F         0.131  -0.022  -0.003   0.090  -0.232  -0.206   0.033  -0.211  -0.189
238   V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
239   S        -0.931  -0.955  -0.933  -0.891  -0.955  -0.882  -0.932  -0.932  -0.895
240   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
241   R         0.131   0.287   0.066   0.268   0.516   0.141   0.033   0.276  -0.075
242   H         0.131  -0.022  -0.003   0.287   0.013   0.044   0.033  -0.211  -0.189
243   K         0.131   0.240   0.055   0.098   0.264   0.003   0.033   0.205  -0.094
244   E         0.131  -0.022  -0.003   0.255   0.027   0.055   0.033  -0.211  -0.189
245   T        -0.931  -0.955  -0.933  -0.886  -0.935  -0.897  -0.932  -0.932  -0.895
246   G         0.131   0.240   0.055   0.190   0.372   0.047   0.033   0.205  -0.094
247   T        -1.702  -1.602  -1.583  -1.679  -1.530  -1.478  -1.415  -1.266  -1.230
248   I         0.131   0.287   0.066   0.116   0.354   0.011   0.033   0.276  -0.075
249   F        -0.931  -0.955  -0.933  -1.045  -1.162  -1.090  -0.932  -0.932  -0.895
250   V         0.131  -0.022  -0.003   0.119  -0.135  -0.104   0.033  -0.211  -0.189
251   V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
252   L        -0.931  -0.928  -0.923  -1.069  -1.028  -1.074  -0.932  -0.904  -0.883
253   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
254   T         1.382   1.434   1.451   1.449   1.526   1.553   1.481   1.542   1.570
255   H         1.382   1.434   1.451   1.533   1.596   1.635   1.481   1.542   1.570
256   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
257   Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
258   W         1.382   1.434   1.451   1.636   1.708   1.735   1.481   1.542   1.570
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   K         1.382   1.434   1.451   1.280   1.359   1.390   1.481   1.542   1.570
262   Y         0.131  -0.022  -0.003   0.156  -0.093  -0.059   0.033  -0.211  -0.189
263   D         0.131  -0.022  -0.003   0.138  -0.117  -0.089   0.033  -0.211  -0.189
264   E        -0.160  -0.096  -0.056  -0.317  -0.208  -0.143  -0.449  -0.336  -0.279
265   V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
266   K         1.382   1.434   1.451   1.280   1.359   1.390   1.481   1.542   1.570
267   L         0.131  -0.022  -0.003  -0.180  -0.401  -0.372   0.033  -0.211  -0.189
268   T        -0.931  -0.955  -0.933  -0.903  -0.955  -0.919  -0.932  -0.932  -0.895
269   Q         1.382   1.434   1.451   1.545   1.623   1.647   1.481   1.542   1.570
270   C         0.131  -0.022  -0.003   0.419   0.153   0.175   0.033  -0.211  -0.189
271   M        -0.931  -0.955  -0.933  -0.940  -1.008  -1.018  -0.932  -0.932  -0.895
272   I         0.131  -0.022  -0.003   0.021  -0.282  -0.268   0.033  -0.211  -0.189
273   I         0.131  -0.022  -0.003   0.021  -0.282  -0.268   0.033  -0.211  -0.189
274   M         0.131  -0.022  -0.003   0.244  -0.071  -0.068   0.033  -0.211  -0.189
275   R         0.131  -0.022  -0.003   0.298   0.030   0.052   0.033  -0.211  -0.189
276   E        -0.931  -0.955  -0.933  -0.942  -0.992  -0.966  -0.932  -0.932  -0.895
277   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
278   S        -1.702  -1.602  -1.583  -1.366  -1.204  -1.175  -1.415  -1.266  -1.230
279   K        -0.931  -0.928  -0.923  -0.846  -0.854  -0.861  -0.932  -0.904  -0.883
280   I         0.131  -0.022  -0.003   0.140  -0.112  -0.073   0.033  -0.211  -0.189
281   I         1.382   1.434   1.451   1.363   1.437   1.470   1.481   1.542   1.570
282   K        -0.931  -0.930  -0.925  -1.005  -0.999  -0.973  -0.932  -0.906  -0.885
283   Q        -1.702  -1.602  -1.583  -1.496  -1.308  -1.301  -1.415  -1.266  -1.230
284   L        -0.931  -0.930  -0.925  -1.159  -1.138  -1.087  -0.932  -0.906  -0.885
285   L         0.131  -0.022  -0.003  -0.080  -0.251  -0.211   0.033  -0.211  -0.189
286   P        -1.702  -1.602  -1.583  -1.663  -1.573  -1.463  -1.415  -1.266  -1.230
287   G         0.131  -0.022  -0.003   0.308   0.096   0.125   0.033  -0.211  -0.189
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   D        -0.034   0.039  -0.035  -0.075   0.050  -0.095  -0.235  -0.111  -0.243
290   V        -1.062  -1.019  -0.954  -1.126  -1.040  -0.943  -1.093  -1.002  -0.919
291   K        -0.034   0.039  -0.035  -0.193  -0.064  -0.217  -0.235  -0.111  -0.243
292   G        -0.034   0.039  -0.035  -0.036   0.087  -0.048  -0.235  -0.111  -0.243
293   Q        -1.062  -1.019  -0.954  -1.077  -1.000  -0.895  -1.093  -1.002  -0.919
294   E        -1.062  -1.019  -0.954  -1.116  -1.034  -0.933  -1.093  -1.002  -0.919
295   R        -1.702  -1.602  -1.583  -1.629  -1.460  -1.430  -1.415  -1.266  -1.230
296   V        -0.931  -0.930  -0.925  -0.919  -0.902  -0.895  -0.932  -0.906  -0.885
297   K         0.131  -0.022  -0.003   0.132  -0.067  -0.027   0.033  -0.211  -0.189
298   I         1.382   1.434   1.451   1.363   1.437   1.470   1.481   1.542   1.570
299   L         0.131  -0.022  -0.003  -0.180  -0.401  -0.372   0.033  -0.211  -0.189
300   F         0.131  -0.022  -0.003   0.258   0.022   0.067   0.033  -0.211  -0.189
301   T        -0.931  -0.955  -0.933  -0.769  -0.766  -0.754  -0.932  -0.932  -0.895
302   G         1.382   1.434   1.451   1.465   1.546   1.569   1.481   1.542   1.570
303   D         1.382   1.434   1.451   1.380   1.457   1.486   1.481   1.542   1.570
304   L        -0.160  -0.085  -0.049  -0.559  -0.382  -0.326  -0.449  -0.317  -0.268
305   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
306   S         1.382   1.434   1.451   1.388   1.464   1.494   1.481   1.542   1.570
307   T        -0.931  -0.955  -0.933  -0.886  -0.935  -0.897  -0.932  -0.932  -0.895
308   R        -0.931  -0.930  -0.925  -0.751  -0.750  -0.750  -0.932  -0.906  -0.885
309   D         0.131  -0.022  -0.003   0.142  -0.108  -0.082   0.033  -0.211  -0.189
310   S         1.382   1.434   1.451   1.388   1.464   1.494   1.481   1.542   1.570
311   L         0.131  -0.022  -0.003  -0.209  -0.443  -0.419   0.033  -0.211  -0.189
312   V         1.382   1.434   1.451   1.359   1.430   1.466   1.481   1.542   1.570
313   V        -0.931  -0.928  -0.923  -0.947  -0.948  -0.927  -0.932  -0.904  -0.883
314   N        -0.931  -0.955  -0.933  -0.921  -0.923  -0.914  -0.932  -0.932  -0.895
315   F         0.131  -0.022  -0.003   0.090  -0.232  -0.206   0.033  -0.211  -0.189
316   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
317   Q        -0.931  -0.733  -0.879  -0.921  -0.602  -0.829  -0.932  -0.651  -0.829
318   G         0.131  -0.022  -0.003   0.244   0.002   0.022   0.033  -0.211  -0.189
319   Q        -0.931  -0.955  -0.933  -0.810  -0.841  -0.838  -0.932  -0.932  -0.895
320   I         0.131  -0.022  -0.003   0.146  -0.095  -0.064   0.033  -0.211  -0.189
321   V        -0.160  -0.085  -0.049  -0.392  -0.260  -0.198  -0.449  -0.317  -0.268
322   S        -0.931  -0.955  -0.933  -0.983  -1.018  -0.996  -0.932  -0.932  -0.895
323   H         0.131  -0.022  -0.003   0.360   0.123   0.160   0.033  -0.211  -0.189
324   G        -0.931  -0.930  -0.925  -0.851  -0.857  -0.846  -0.932  -0.906  -0.885
325   D        -0.931  -0.930  -0.925  -0.992  -1.014  -0.989  -0.932  -0.906  -0.885
326   L        -0.931  -0.955  -0.933  -1.110  -1.047  -1.033  -0.932  -0.932  -0.895
327   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
328   L        -0.931  -0.930  -0.925  -1.209  -1.155  -1.147  -0.932  -0.906  -0.885
329   I        -0.931  -0.955  -0.933  -0.867  -0.908  -0.843  -0.932  -0.932  -0.895
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   N         0.131  -0.022  -0.003   0.185  -0.051  -0.009   0.033  -0.211  -0.189
348   P         0.131  -0.022  -0.003   0.251  -0.019   0.009   0.033  -0.211  -0.189
349   M         0.131  -0.022  -0.003   0.361   0.104   0.124   0.033  -0.211  -0.189
350   R        -0.931  -0.930  -0.925  -0.848  -0.863  -0.867  -0.932  -0.906  -0.885
351   P         0.131   0.240   0.055   0.329   0.487   0.224   0.033   0.205  -0.094
352   Y         0.131  -0.022  -0.003   0.156  -0.093  -0.059   0.033  -0.211  -0.189
353   L         0.131  -0.022  -0.003  -0.121  -0.316  -0.276   0.033  -0.211  -0.189
354   D        -1.702  -1.602  -1.583  -1.802  -1.691  -1.598  -1.415  -1.266  -1.230
355   R        -0.931  -0.928  -0.923  -0.652  -0.643  -0.625  -0.932  -0.904  -0.883
356   C         0.131   0.240   0.055   0.400   0.566   0.256   0.033   0.205  -0.094
357   V        -0.931  -0.955  -0.933  -0.872  -0.866  -0.848  -0.932  -0.932  -0.895
358   Y         1.382   1.434   1.451   1.380   1.458   1.486   1.481   1.542   1.570
359   D         0.131  -0.022  -0.003   0.160  -0.080  -0.052   0.033  -0.211  -0.189
360   D         0.131  -0.022  -0.003   0.037  -0.264  -0.253   0.033  -0.211  -0.189
361   I        -0.931  -0.930  -0.925  -1.110  -1.170  -1.127  -0.932  -0.906  -0.885
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
370   K        -0.931  -0.928  -0.923  -0.861  -0.829  -0.849  -0.932  -0.904  -0.883
371   D        -0.931  -0.930  -0.925  -0.962  -0.985  -0.952  -0.932  -0.906  -0.885
372   Y        -1.702  -1.602  -1.583  -1.766  -1.584  -1.563  -1.415  -1.266  -1.230
373   F        -0.931  -0.955  -0.933  -1.038  -1.153  -1.081  -0.932  -0.932  -0.895
374   V        -0.931  -0.930  -0.925  -0.907  -0.902  -0.880  -0.932  -0.906  -0.885
375   H         0.131  -0.022  -0.003   0.304   0.030   0.071   0.033  -0.211  -0.189
376   T         1.382   1.434   1.451   1.449   1.526   1.553   1.481   1.542   1.570
377   C         0.131  -0.022  -0.003   0.400   0.123   0.145   0.033  -0.211  -0.189
378   Y         0.131  -0.022  -0.003   0.156  -0.093  -0.059   0.033  -0.211  -0.189
379   S         0.131  -0.022  -0.003   0.169  -0.071  -0.043   0.033  -0.211  -0.189
380   G         0.131  -0.022  -0.003   0.190  -0.079  -0.065   0.033  -0.211  -0.189
381   K         0.131  -0.022  -0.003   0.071  -0.155  -0.126   0.033  -0.211  -0.189
382   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
383   K         0.131  -0.022  -0.003   0.037  -0.210  -0.180   0.033  -0.211  -0.189
384   G         0.131  -0.022  -0.003   0.222  -0.031  -0.014   0.033  -0.211  -0.189
385   I         0.131  -0.022  -0.003   0.116  -0.143  -0.111   0.033  -0.211  -0.189
386   F         0.131  -0.022  -0.003   0.184  -0.094  -0.052   0.033  -0.211  -0.189
387   D         1.382   1.434   1.451   1.380   1.457   1.486   1.481   1.542   1.570
388   Y         0.131  -0.022  -0.003   0.189  -0.041  -0.006   0.033  -0.211  -0.189
389   V         0.131   0.290   0.068   0.116   0.359   0.014   0.033   0.282  -0.072
390   W         1.382   1.434   1.451   1.636   1.708   1.735   1.481   1.542   1.570
391   Y         0.131   0.240   0.055   0.156   0.323   0.039   0.033   0.205  -0.094
392   H         0.131  -0.022  -0.003   0.290   0.016   0.048   0.033  -0.211  -0.189
393   D        -0.931  -0.955  -0.933  -0.937  -0.999  -0.935  -0.932  -0.932  -0.895
394   S        -1.702  -1.602  -1.583  -1.577  -1.416  -1.380  -1.415  -1.266  -1.230
395   D         0.131  -0.022  -0.003   0.189  -0.042  -0.006   0.033  -0.211  -0.189
396   F         1.382   1.434   1.451   1.433   1.491   1.538   1.481   1.542   1.570
397   L        -0.931  -0.768  -0.880  -1.146  -0.845  -1.061  -0.932  -0.696  -0.831
398   L        -0.160  -0.085  -0.049  -0.617  -0.436  -0.387  -0.449  -0.317  -0.268
399   T        -0.931  -0.771  -0.876  -0.790  -0.535  -0.693  -0.932  -0.699  -0.826
400   K         0.131   0.287   0.066   0.098   0.328   0.020   0.033   0.276  -0.075
401   I        -0.931  -0.955  -0.933  -1.110  -1.209  -1.145  -0.932  -0.932  -0.895
402   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
403   T        -0.034   0.039  -0.035  -0.080   0.043  -0.087  -0.235  -0.111  -0.243
404   G         1.382   1.434   1.451   1.465   1.546   1.569   1.481   1.542   1.570
405   N        -1.702  -1.602  -1.583  -1.451  -1.291  -1.258  -1.415  -1.266  -1.230
406   E         0.131  -0.022  -0.003   0.196  -0.068  -0.042   0.033  -0.211  -0.189
407   V         0.131  -0.022  -0.003   0.119  -0.136  -0.104   0.033  -0.211  -0.189
408   S         0.131  -0.022  -0.003   0.201  -0.022   0.007   0.033  -0.211  -0.189
409   D        -1.702  -1.602  -1.583  -1.629  -1.464  -1.430  -1.415  -1.266  -1.230
410   E         0.131  -0.022  -0.003   0.202  -0.054  -0.031   0.033  -0.211  -0.189
411   L         0.131  -0.022  -0.003  -0.175  -0.390  -0.363   0.033  -0.211  -0.189
412   L        -0.931  -0.733  -0.879  -0.921  -0.575  -0.839  -0.932  -0.651  -0.829
413   A        -0.931  -0.955  -0.933  -0.662  -0.723  -0.676  -0.932  -0.932  -0.895
414   S        -0.931  -0.928  -0.923  -1.194  -1.135  -1.127  -0.932  -0.904  -0.883
415   N         0.131  -0.022  -0.003   0.163  -0.076  -0.045   0.033  -0.211  -0.189
416   Q        -0.931  -0.955  -0.933  -0.813  -0.875  -0.842  -0.932  -0.932  -0.895
417   L        -0.931  -0.928  -0.923  -1.047  -1.047  -1.070  -0.932  -0.904  -0.883
418   G         1.382   1.434   1.451   1.465   1.546   1.569   1.481   1.542   1.570
419   L         0.131  -0.022  -0.003  -0.156  -0.373  -0.333   0.033  -0.211  -0.189
420   P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
421   N         1.382   1.434   1.451   1.376   1.447   1.482   1.481   1.542   1.570
422   E        -0.931  -0.955  -0.933  -0.930  -0.971  -0.950  -0.932  -0.932  -0.895
423   N        -0.931  -0.955  -0.933  -0.879  -0.884  -0.863  -0.932  -0.932  -0.895
424   H         0.131  -0.022  -0.003   0.304   0.030   0.071   0.033  -0.211  -0.189
425   P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
426   S         1.382   1.434   1.451   1.388   1.464   1.494   1.481   1.542   1.570
427   D         1.382   1.434   1.451   1.380   1.457   1.486   1.481   1.542   1.570
428   H         1.382   1.434   1.451   1.533   1.596   1.635   1.481   1.542   1.570
429   I         1.382   1.434   1.451   1.363   1.437   1.470   1.481   1.542   1.570
430   P         1.382   1.434   1.451   1.501   1.571   1.604   1.481   1.542   1.570
431   L         0.131   0.240   0.055  -0.182   0.001  -0.283   0.033   0.205  -0.094
432   L        -0.931  -0.930  -0.925  -1.215  -1.192  -1.154  -0.932  -0.906  -0.885
433   T         1.382   1.434   1.451   1.449   1.526   1.553   1.481   1.542   1.570
434   E         1.382   1.434   1.451   1.445   1.520   1.549   1.481   1.542   1.570
435   F        -0.160  -0.085  -0.049  -0.559  -0.465  -0.393  -0.449  -0.317  -0.268
436   K        -1.702  -1.602  -1.583  -1.466  -1.253  -1.272  -1.415  -1.266  -1.230
437   I         0.131  -0.022  -0.003   0.123  -0.129  -0.101   0.033  -0.211  -0.189
438   L         1.382   1.434   1.451   1.059   1.149   1.175   1.481   1.542   1.570
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08213
Output conservation file - output/Q08213
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
