1     M         1.843   1.894   1.978   2.063   2.150   2.284   2.046   2.131   2.283
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     F         1.843   1.894   1.978   1.875   1.947   2.097   2.046   2.131   2.283
7     A         0.563   0.722   0.741   0.283   0.554   0.574   0.200   0.484   0.472
8     A         0.420   0.292   0.106   0.440   0.247  -0.022   0.446   0.253  -0.033
9     I         0.755   0.836   0.775   0.680   0.814   0.691   0.569   0.700   0.540
10    A        -0.042  -0.057  -0.010   0.032   0.075   0.129  -0.293  -0.273  -0.217
11    S         0.563   0.555   0.653   0.199   0.144   0.303   0.200   0.153   0.291
12    G         1.843   1.894   1.978   1.822   1.886   2.044   2.046   2.131   2.283
13    N        -0.042  -0.057  -0.010   0.002   0.067   0.106  -0.293  -0.273  -0.217
14    P         0.420   0.347   0.125   0.587   0.472   0.163   0.446   0.337  -0.004
15    L        -1.048  -0.996  -1.043  -1.024  -0.950  -0.977  -0.908  -0.854  -0.856
16    Q         0.420   0.309   0.122   0.655   0.518   0.226   0.446   0.276  -0.007
17    L        -0.504  -0.542  -0.574  -0.524  -0.609  -0.592  -0.539  -0.599  -0.601
18    S        -0.504  -0.528  -0.567  -0.601  -0.629  -0.698  -0.539  -0.554  -0.588
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    V        -1.177  -1.072  -1.041  -1.161  -1.041  -0.976  -1.017  -0.909  -0.851
21    E         0.101   0.125   0.013   0.212   0.244   0.053  -0.046  -0.040  -0.185
22    V        -0.042  -0.057  -0.010  -0.114  -0.102  -0.049  -0.293  -0.273  -0.217
23    P        -0.042   0.003  -0.026  -0.147  -0.113  -0.106  -0.293  -0.240  -0.251
24    N        -1.048  -1.121  -1.051  -1.026  -1.135  -1.019  -0.908  -0.964  -0.863
25    S        -1.048  -1.075  -1.043  -1.017  -1.043  -0.983  -0.908  -0.923  -0.856
26    N         0.563   0.579   0.660   0.245   0.266   0.379   0.200   0.200   0.306
27    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    T        -0.586  -0.685  -0.599  -0.610  -0.723  -0.608  -0.662  -0.739  -0.628
32    I        -0.251  -0.199  -0.099  -0.291  -0.182  -0.045  -0.539  -0.468  -0.341
33    V         0.420   0.292   0.106   0.576   0.372   0.101   0.446   0.253  -0.033
34    L        -0.251  -0.199  -0.099  -0.524  -0.418  -0.271  -0.539  -0.468  -0.341
35    S        -1.048  -1.072  -1.052  -1.032  -1.055  -1.032  -0.908  -0.924  -0.865
36    R        -1.510  -1.482  -1.410  -1.395  -1.390  -1.230  -1.154  -1.116  -1.009
37    T        -0.840  -0.844  -0.980  -0.648  -0.650  -0.891  -0.662  -0.664  -0.790
38    K        -0.042  -0.013   0.000  -0.241  -0.154  -0.160  -0.293  -0.215  -0.201
39    P        -0.042  -0.008  -0.030  -0.230  -0.218  -0.200  -0.293  -0.251  -0.256
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    K        -0.504  -0.528  -0.567  -0.436  -0.445  -0.529  -0.539  -0.554  -0.588
50    L        -1.048  -1.039  -1.008  -1.145  -1.138  -1.101  -0.908  -0.895  -0.826
51    Y        -1.048  -1.140  -1.065  -0.801  -0.966  -0.882  -0.908  -0.977  -0.876
52    S         0.101  -0.052  -0.028  -0.028  -0.267  -0.252  -0.046  -0.264  -0.245
53    H         1.114   1.175   0.932   1.514   1.611   1.305   1.185   1.280   0.843
54    I         1.114   0.977   0.899   1.185   1.026   0.902   1.185   0.951   0.780
55    T        -0.586  -0.416  -0.559  -0.671  -0.437  -0.629  -0.662  -0.470  -0.588
56    L        -0.251  -0.149  -0.084  -0.533  -0.349  -0.261  -0.539  -0.397  -0.319
57    F         1.843   1.894   1.978   1.875   1.947   2.097   2.046   2.131   2.283
58    I         0.502   0.580   0.670   0.128   0.258   0.387   0.077   0.202   0.326
59    L         1.843   1.894   1.978   1.703   1.789   1.926   2.046   2.131   2.283
60    P         1.843   1.894   1.978   1.834   1.895   2.056   2.046   2.131   2.283
61    N         0.101   0.099  -0.006   0.020  -0.008  -0.137  -0.046  -0.085  -0.216
62    V        -0.504  -0.469  -0.565  -0.516  -0.511  -0.654  -0.539  -0.507  -0.592
63    T        -0.504  -0.581  -0.587  -0.444  -0.592  -0.557  -0.539  -0.634  -0.616
64    F         0.755   0.697   0.703   0.700   0.572   0.541   0.569   0.436   0.394
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    P         0.563   0.626   0.678   0.407   0.495   0.575   0.200   0.295   0.342
67    Q        -1.510  -1.412  -1.404  -1.397  -1.270  -1.276  -1.154  -1.056  -1.005
68    D        -1.175  -1.041  -1.057  -1.137  -0.961  -0.959  -1.031  -0.896  -0.869
69    Y        -1.048  -1.126  -1.028  -0.692  -0.806  -0.677  -0.908  -0.962  -0.844
70    I        -1.175  -1.098  -1.060  -1.300  -1.206  -1.144  -1.031  -0.947  -0.871
71    A         1.843   1.894   1.978   1.703   1.775   1.926   2.046   2.131   2.283
72    T        -1.048  -1.140  -1.065  -1.103  -1.262  -1.164  -0.908  -0.977  -0.876
73    V         0.755   0.705   0.704   0.700   0.595   0.569   0.569   0.452   0.396
74    Y         1.843   1.894   1.978   2.045   2.133   2.266   2.046   2.131   2.283
75    F         1.114   0.977   0.899   1.232   1.044   0.922   1.185   0.951   0.780
76    K        -0.042  -0.057  -0.010  -0.071  -0.037   0.012  -0.293  -0.273  -0.217
77    L         0.420   0.189   0.088   0.503   0.214   0.082   0.446   0.108  -0.060
78    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    P         1.843   1.894   1.978   1.834   1.895   2.056   2.046   2.131   2.283
80    Q        -1.510  -1.406  -1.396  -1.445  -1.320  -1.310  -1.154  -1.058  -1.000
81    E        -1.048  -1.133  -1.055  -0.900  -1.039  -0.947  -0.908  -0.973  -0.867
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    E        -0.586  -0.692  -0.580  -0.493  -0.629  -0.482  -0.662  -0.748  -0.611
88    F         1.114   1.175   0.932   1.281   1.364   1.082   1.185   1.280   0.843
89    K         0.755   0.730   0.724   0.754   0.725   0.677   0.569   0.500   0.437
90    L         0.755   0.649   0.691   0.588   0.406   0.465   0.569   0.341   0.370
91    F         0.563   0.722   0.741   0.270   0.530   0.551   0.200   0.484   0.472
92    G         1.843   1.894   1.978   1.822   1.886   2.044   2.046   2.131   2.283
93    Y        -0.042  -0.013  -0.035  -0.006   0.005  -0.020  -0.293  -0.260  -0.262
94    L         0.755   0.705   0.704   0.566   0.484   0.448   0.569   0.452   0.396
95    S        -0.713  -0.732  -0.625  -0.919  -0.944  -0.780  -0.785  -0.791  -0.659
96    S        -0.713  -0.579  -0.615  -0.883  -0.700  -0.753  -0.785  -0.640  -0.650
97    E        -0.840  -0.883  -1.002  -0.587  -0.669  -0.930  -0.662  -0.710  -0.812
98    K         1.843   1.894   1.978   1.866   1.960   2.088   2.046   2.131   2.283
99    P         1.114   0.977   0.899   1.223   1.043   0.955   1.185   0.951   0.780
100   S         1.843   1.894   1.978   1.729   1.811   1.952   2.046   2.131   2.283
101   A         1.843   1.894   1.978   1.703   1.775   1.926   2.046   2.131   2.283
102   I         1.843   1.894   1.978   1.809   1.903   2.031   2.046   2.131   2.283
103   F         0.755   0.836   0.775   0.810   0.925   0.841   0.569   0.700   0.540
104   K         1.114   1.037   0.911   1.276   1.216   1.053   1.185   1.055   0.804
105   V         0.502   0.554   0.655   0.152   0.219   0.385   0.077   0.151   0.294
106   Q        -0.840  -0.798  -0.950  -0.601  -0.555  -0.811  -0.662  -0.624  -0.759
107   I        -0.504  -0.418  -0.539  -0.607  -0.449  -0.650  -0.539  -0.424  -0.553
108   P         0.541   0.556   0.657   0.282   0.239   0.437   0.156   0.154   0.300
109   S        -0.198  -0.216  -0.087  -0.423  -0.491  -0.284  -0.475  -0.492  -0.325
110   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   D        -1.011  -0.837  -0.981  -0.880  -0.631  -0.860  -0.848  -0.655  -0.791
117   T         0.302   0.135   0.028   0.416   0.177  -0.006   0.278   0.025  -0.151
118   -        -1.177  -1.120  -1.062  -1.280  -1.196  -1.129  -1.017  -0.954  -0.871
119   -        -1.177  -1.085  -1.045  -1.202  -1.060  -1.026  -1.017  -0.915  -0.855
120   -        -1.177  -1.158  -1.086  -1.159  -1.172  -1.066  -1.017  -0.990  -0.894
121   S         0.685   0.754   0.700   0.427   0.534   0.396   0.438   0.546   0.388
122   D        -0.390  -0.484  -0.575  -0.147  -0.275  -0.450  -0.365  -0.490  -0.593
123   G        -0.628  -0.681  -0.625  -0.630  -0.745  -0.655  -0.687  -0.741  -0.656
124   L         0.302   0.171   0.049   0.316   0.138  -0.036   0.278   0.075  -0.118
125   G        -0.100  -0.139  -0.061  -0.187  -0.233  -0.132  -0.365  -0.392  -0.290
126   E        -0.628  -0.711  -0.639  -0.422  -0.497  -0.405  -0.687  -0.767  -0.670
127   I        -0.006  -0.063  -0.053  -0.064  -0.155  -0.133  -0.205  -0.298  -0.282
128   D        -0.006  -0.109  -0.054   0.059  -0.077  -0.018  -0.205  -0.344  -0.282
129   M         1.049   0.915   0.844   1.345   1.165   1.030   1.082   0.843   0.676
130   D        -0.735  -0.661  -0.625  -0.730  -0.633  -0.590  -0.790  -0.704  -0.653
131   V        -0.114  -0.051  -0.029  -0.100   0.008   0.056  -0.361  -0.263  -0.240
132   D         0.971   0.979   0.812   1.043   1.061   0.765   0.952   0.956   0.613
133   D        -0.561  -0.567  -0.599  -0.436  -0.451  -0.529  -0.580  -0.591  -0.622
134   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   N        -0.100   0.007  -0.026  -0.308  -0.127  -0.143  -0.365  -0.210  -0.240
146   G         1.049   1.030   0.874   1.079   1.033   0.811   1.082   1.043   0.733
147   S         0.004   0.221   0.008  -0.023   0.320  -0.068  -0.160   0.156  -0.181
148   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   S        -1.177  -1.029  -1.039  -1.258  -1.006  -1.074  -1.017  -0.861  -0.849
150   N        -0.561  -0.657  -0.638  -0.658  -0.835  -0.848  -0.580  -0.702  -0.668
151   -        -0.730  -0.666  -0.622  -0.621  -0.562  -0.501  -0.799  -0.719  -0.651
152   N        -0.628  -0.645  -0.617  -0.684  -0.696  -0.630  -0.687  -0.703  -0.647
153   I        -1.011  -1.102  -1.069  -0.861  -1.003  -0.966  -0.848  -0.938  -0.878
154   S        -1.011  -1.102  -1.069  -0.976  -1.115  -1.081  -0.848  -0.938  -0.878
155   E        -1.048  -0.981  -1.022  -0.936  -0.860  -0.898  -0.908  -0.826  -0.834
156   L        -0.586  -0.685  -0.599  -0.739  -0.853  -0.734  -0.662  -0.739  -0.628
157   I        -1.048  -1.140  -1.065  -0.985  -1.083  -0.992  -0.908  -0.977  -0.876
158   I         1.114   1.037   0.911   1.166   1.088   0.880   1.185   1.055   0.804
159   G         1.843   1.894   1.978   1.822   1.886   2.044   2.046   2.131   2.283
160   I         1.114   0.977   0.899   1.185   1.026   0.902   1.185   0.951   0.780
161   S         1.843   1.894   1.978   1.729   1.811   1.952   2.046   2.131   2.283
162   I         0.755   0.649   0.691   0.680   0.490   0.535   0.569   0.341   0.370
163   E         1.843   1.894   1.978   1.928   2.020   2.150   2.046   2.131   2.283
164   P         0.420   0.397   0.142   0.588   0.546   0.194   0.446   0.392   0.022
165   R        -1.048  -1.140  -1.065  -0.832  -1.034  -0.950  -0.908  -0.977  -0.876
166   E        -0.713  -0.732  -0.622  -0.806  -0.814  -0.651  -0.785  -0.790  -0.655
167   Q        -1.384  -1.376  -1.374  -1.096  -1.136  -1.129  -1.031  -1.024  -0.979
168   G        -0.713  -0.704  -0.612  -0.855  -0.853  -0.689  -0.785  -0.761  -0.644
169   M        -0.713  -0.713  -0.617  -0.621  -0.647  -0.512  -0.785  -0.765  -0.649
170   M        -1.510  -1.461  -1.393  -1.328  -1.275  -1.153  -1.154  -1.103  -0.998
171   K        -1.048  -1.140  -1.065  -0.907  -0.997  -0.906  -0.908  -0.977  -0.876
172   L        -0.504  -0.621  -0.556  -0.513  -0.631  -0.554  -0.539  -0.655  -0.580
173   E        -1.510  -1.434  -1.412  -1.315  -1.266  -1.176  -1.154  -1.076  -1.011
174   E        -0.245  -0.174  -0.094  -0.388  -0.325  -0.192  -0.526  -0.441  -0.335
175   W        -1.011  -1.102  -1.069  -0.657  -0.861  -0.863  -0.848  -0.938  -0.878
176   K         0.302   0.179   0.046   0.504   0.320   0.149   0.278   0.080  -0.124
177   A        -0.628  -0.673  -0.598  -0.721  -0.796  -0.666  -0.687  -0.724  -0.628
178   S        -1.177  -1.107  -1.051  -1.144  -1.058  -0.962  -1.017  -0.947  -0.861
179   M        -0.561  -0.587  -0.592  -0.302  -0.361  -0.339  -0.580  -0.623  -0.614
180   N        -1.177  -1.110  -1.055  -1.202  -1.116  -1.025  -1.017  -0.951  -0.865
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   A        -0.245  -0.168  -0.083  -0.598  -0.497  -0.350  -0.526  -0.431  -0.320
184   E        -1.156  -1.098  -1.059  -1.281  -1.222  -1.133  -1.008  -0.945  -0.870
185   A         0.685   0.668   0.685   0.424   0.364   0.362   0.438   0.380   0.357
186   Q        -0.283  -0.219  -0.121  -0.553  -0.477  -0.318  -0.580  -0.497  -0.371
187   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   S         0.522   0.552   0.655   0.101   0.118   0.293   0.117   0.146   0.294
191   L         0.302   0.249   0.069   0.362   0.270   0.052   0.278   0.171  -0.088
192   I         0.420   0.400   0.151   0.589   0.536   0.204   0.446   0.395   0.036
193   L        -0.251  -0.149  -0.084  -0.601  -0.435  -0.337  -0.539  -0.397  -0.319
194   S        -0.504  -0.585  -0.534  -0.618  -0.730  -0.654  -0.539  -0.609  -0.547
195   R        -1.175  -1.040  -1.049  -1.114  -0.978  -0.962  -1.031  -0.901  -0.863
196   P        -0.735  -0.583  -0.605  -0.835  -0.630  -0.656  -0.790  -0.617  -0.629
197   N        -0.198  -0.014  -0.073  -0.498  -0.189  -0.310  -0.475  -0.222  -0.305
198   L        -1.271  -1.142  -1.098  -1.329  -1.097  -1.085  -1.105  -0.978  -0.904
199   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   N         0.004   0.287   0.039  -0.040   0.363  -0.004  -0.160   0.253  -0.134
204   I         0.611   0.573   0.656   0.357   0.240   0.360   0.296   0.188   0.298
205   T        -1.177  -1.030  -1.041  -1.367  -1.122  -1.188  -1.017  -0.862  -0.851
206   T        -1.048  -1.072  -1.052  -1.105  -1.180  -1.152  -0.908  -0.924  -0.865
207   A        -0.504  -0.627  -0.573  -0.579  -0.780  -0.684  -0.539  -0.663  -0.600
208   G        -1.384  -1.456  -1.421  -1.209  -1.379  -1.326  -1.031  -1.087  -1.017
209   Q        -1.510  -1.438  -1.401  -1.431  -1.353  -1.301  -1.154  -1.077  -1.002
210   L        -0.713  -0.740  -0.635  -0.960  -1.003  -0.839  -0.785  -0.800  -0.669
211   A        -0.234  -0.146  -0.465  -0.174  -0.060  -0.533  -0.169  -0.054  -0.458
212   Q        -0.504  -0.538  -0.539  -0.345  -0.345  -0.386  -0.539  -0.565  -0.562
213   V        -1.175  -1.144  -1.050  -1.190  -1.132  -1.007  -1.031  -0.983  -0.863
214   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   P        -0.234  -0.435  -0.532  -0.044  -0.360  -0.532  -0.169  -0.427  -0.542
216   S        -1.510  -1.305  -1.398  -1.485  -1.176  -1.323  -1.154  -0.972  -1.000
217   L        -1.846  -1.819  -1.733  -1.724  -1.701  -1.560  -1.277  -1.241  -1.126
218   T         0.420   0.393   0.138   0.555   0.519   0.158   0.446   0.401   0.017
219   Q        -0.586  -0.685  -0.599  -0.680  -0.832  -0.711  -0.662  -0.739  -0.628
220   E        -0.713  -0.690  -0.636  -0.746  -0.751  -0.667  -0.785  -0.758  -0.670
221   L         0.420   0.364   0.140   0.503   0.438   0.157   0.446   0.361   0.020
222   A         1.843   1.894   1.978   1.703   1.775   1.926   2.046   2.131   2.283
223   A        -0.713  -0.587  -0.617  -0.885  -0.676  -0.719  -0.785  -0.658  -0.649
224   K         1.114   0.977   0.899   1.276   1.139   1.035   1.185   0.951   0.780
225   I         1.843   1.894   1.978   1.809   1.903   2.031   2.046   2.131   2.283
226   V         0.101  -0.030  -0.029   0.090  -0.141  -0.156  -0.046  -0.244  -0.249
227   Q        -0.504  -0.595  -0.588  -0.387  -0.529  -0.537  -0.539  -0.645  -0.617
228   H         0.563   0.555   0.653   0.552   0.479   0.604   0.200   0.153   0.291
229   A         1.114   1.037   0.911   1.059   0.959   0.776   1.185   1.055   0.804
230   Y         1.114   0.977   0.899   1.425   1.261   1.139   1.185   0.951   0.780
231   N         1.843   1.894   1.978   1.722   1.819   1.945   2.046   2.131   2.283
232   Y         0.563   0.559   0.654   0.570   0.523   0.661   0.200   0.161   0.292
233   L         1.843   1.894   1.978   1.703   1.789   1.926   2.046   2.131   2.283
234   S        -0.713  -0.604  -0.587  -0.935  -0.797  -0.747  -0.785  -0.661  -0.616
235   G         0.502   0.576   0.667   0.157   0.260   0.410   0.077   0.196   0.319
236   F         1.114   0.977   0.899   1.281   1.119   1.033   1.185   0.951   0.780
237   L        -1.175  -1.098  -1.060  -1.294  -1.183  -1.119  -1.031  -0.947  -0.871
238   D        -0.234  -0.435  -0.532   0.062  -0.234  -0.413  -0.169  -0.427  -0.542
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   A        -1.048  -1.024  -1.027  -1.094  -1.094  -1.047  -0.908  -0.886  -0.842
255   Q        -1.175  -1.203  -1.063  -1.212  -1.222  -1.045  -1.031  -1.031  -0.875
256   G        -0.234  -0.435  -0.532  -0.052  -0.375  -0.534  -0.169  -0.427  -0.542
257   N        -1.048  -1.140  -1.065  -0.941  -1.046  -0.909  -0.908  -0.977  -0.876
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   V         1.114   1.037   0.911   1.212   1.113   0.944   1.185   1.055   0.804
263   P         0.563   0.675   0.701   0.308   0.488   0.513   0.200   0.392   0.389
264   I        -0.169  -0.187  -0.114  -0.264  -0.323  -0.201  -0.416  -0.455  -0.361
265   K         0.420   0.347   0.125   0.647   0.585   0.250   0.446   0.337  -0.004
266   R        -0.586  -0.586  -0.582  -0.440  -0.474  -0.412  -0.662  -0.637  -0.609
267   F         1.843   1.894   1.978   1.875   1.947   2.097   2.046   2.131   2.283
268   D        -0.504  -0.646  -0.590  -0.375  -0.540  -0.516  -0.539  -0.688  -0.618
269   T        -1.175  -1.118  -1.066  -1.148  -1.021  -0.965  -1.031  -0.966  -0.877
270   W         1.843   1.894   1.978   2.103   2.188   2.323   2.046   2.131   2.283
271   W         1.114   1.037   0.911   1.515   1.446   1.285   1.185   1.055   0.804
272   D        -0.840  -0.929  -0.992  -0.540  -0.696  -0.822  -0.662  -0.766  -0.802
273   K         1.843   1.894   1.978   1.866   1.960   2.088   2.046   2.131   2.283
274   F         1.843   1.894   1.978   1.875   1.947   2.097   2.046   2.131   2.283
275   R        -0.504  -0.585  -0.534  -0.304  -0.406  -0.347  -0.539  -0.609  -0.547
276   N        -1.048  -0.939  -1.015  -1.143  -1.011  -1.108  -0.908  -0.807  -0.832
277   R         0.563   0.722   0.741   0.521   0.777   0.795   0.200   0.484   0.472
278   L         0.420   0.292   0.106   0.503   0.339   0.107   0.446   0.253  -0.033
279   A        -0.504  -0.623  -0.559  -0.491  -0.628  -0.537  -0.539  -0.657  -0.584
280   N         1.114   0.977   0.899   1.092   0.936   0.805   1.185   0.951   0.780
281   D         0.502   0.554   0.655   0.223   0.320   0.453   0.077   0.151   0.294
282   G         0.101   0.358   0.074   0.089   0.448   0.039  -0.046   0.331  -0.085
283   T        -0.840  -0.763  -0.661  -1.091  -0.982  -0.834  -0.908  -0.820  -0.694
284   F         1.843   1.894   1.978   1.875   1.947   2.097   2.046   2.131   2.283
285   L         1.843   1.894   1.978   1.703   1.789   1.926   2.046   2.131   2.283
286   D         0.420   0.309   0.122   0.671   0.553   0.242   0.446   0.276  -0.007
287   E        -0.234  -0.435  -0.532   0.088  -0.180  -0.374  -0.169  -0.427  -0.542
288   V        -0.586  -0.685  -0.599  -0.640  -0.739  -0.609  -0.662  -0.739  -0.628
289   T        -0.251  -0.149  -0.084  -0.374  -0.175  -0.106  -0.539  -0.397  -0.319
290   K        -1.156  -1.150  -1.076  -1.009  -0.961  -0.900  -1.008  -0.991  -0.885
291   N        -1.177  -1.119  -1.057  -1.117  -1.024  -0.948  -1.017  -0.961  -0.867
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q08202
Output conservation file - output/Q08202
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
