1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    M         1.212   1.224   1.288   1.337   1.354   1.445   1.291   1.309   1.404
18    N        -1.110  -1.126  -0.998  -1.254  -1.286  -1.087  -1.125  -1.139  -0.972
19    R        -1.110  -1.126  -0.998  -1.148  -1.173  -0.980  -1.125  -1.139  -0.972
20    I        -1.110  -1.126  -0.998  -1.084  -1.130  -0.977  -1.125  -1.139  -0.972
21    K        -1.110  -1.126  -0.998  -1.116  -1.158  -0.997  -1.125  -1.139  -0.972
22    N        -0.627  -0.610  -0.506  -0.715  -0.676  -0.514  -0.857  -0.830  -0.684
23    T        -1.106  -1.047  -0.971  -1.302  -1.217  -1.092  -1.133  -1.070  -0.947
24    F        -0.551  -0.561  -0.508  -0.665  -0.672  -0.616  -0.760  -0.763  -0.687
25    S        -1.508  -1.482  -1.348  -1.471  -1.444  -1.268  -1.319  -1.289  -1.116
26    V        -1.106  -1.102  -0.993  -1.257  -1.247  -1.060  -1.133  -1.122  -0.968
27    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    S        -1.359  -1.392  -1.332  -1.312  -1.368  -1.295  -1.174  -1.208  -1.103
40    E        -1.834  -1.805  -1.652  -1.590  -1.546  -1.367  -1.448  -1.419  -1.227
41    L         0.497   0.553   0.280   0.453   0.532   0.129   0.469   0.552   0.074
42    P         0.169   0.186   0.168   0.016   0.036  -0.045  -0.079  -0.056  -0.135
43    S        -1.506  -1.493  -1.343  -1.377  -1.354  -1.135  -1.331  -1.307  -1.114
44    I        -1.694  -1.630  -1.628  -1.492  -1.403  -1.429  -1.331  -1.273  -1.209
45    F        -0.486  -0.551  -0.476  -0.439  -0.504  -0.384  -0.701  -0.768  -0.651
46    E        -1.392  -1.373  -1.317  -1.333  -1.315  -1.235  -1.226  -1.198  -1.090
47    G        -0.357  -0.379  -0.451  -0.432  -0.473  -0.585  -0.492  -0.528  -0.615
48    T        -0.357  -0.245  -0.437  -0.374  -0.201  -0.509  -0.492  -0.338  -0.593
49    V         0.059   0.066   0.153  -0.198  -0.190  -0.061  -0.282  -0.277  -0.163
50    D        -1.392  -1.429  -1.346  -1.284  -1.340  -1.233  -1.226  -1.252  -1.116
51    L        -0.070  -0.077  -0.375  -0.037  -0.053  -0.473  -0.072  -0.090  -0.504
52    G         0.059   0.084   0.161  -0.252  -0.218  -0.100  -0.282  -0.244  -0.147
53    I         0.059   0.042   0.146  -0.192  -0.234  -0.073  -0.282  -0.324  -0.177
54    I         1.212   1.224   1.288   1.181   1.201   1.299   1.291   1.309   1.404
55    G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
56    G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
57    T         0.555   0.448   0.293   0.642   0.504   0.245   0.557   0.389   0.098
58    G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
59    L         0.555   0.448   0.293   0.533   0.397   0.174   0.557   0.389   0.098
60    Y         0.555   0.473   0.295   0.782   0.674   0.371   0.557   0.428   0.101
61    N        -1.090  -1.037  -0.977  -1.079  -1.010  -0.915  -1.121  -1.066  -0.953
62    L         1.212   1.224   1.288   1.099   1.116   1.224   1.291   1.309   1.404
63    D        -1.090  -1.062  -0.976  -1.183  -1.138  -1.017  -1.121  -1.084  -0.952
64    C        -1.090  -1.071  -0.982  -1.018  -1.030  -0.915  -1.121  -1.097  -0.958
65    L        -0.070  -0.250  -0.401  -0.005  -0.237  -0.443  -0.072  -0.319  -0.540
66    E        -1.808  -1.821  -1.652  -1.675  -1.690  -1.439  -1.435  -1.432  -1.228
67    P        -0.070  -0.117  -0.379   0.039  -0.028  -0.451  -0.072  -0.145  -0.509
68    I         0.059   0.122   0.174  -0.198  -0.083  -0.021  -0.282  -0.173  -0.124
69    A         0.555   0.448   0.293   0.518   0.367   0.140   0.557   0.389   0.098
70    L        -1.808  -1.822  -1.664  -1.705  -1.745  -1.522  -1.435  -1.433  -1.236
71    L        -0.070  -0.179  -0.393  -0.054  -0.205  -0.539  -0.072  -0.224  -0.528
72    P        -1.090  -1.071  -0.982  -1.110  -1.067  -0.930  -1.121  -1.097  -0.958
73    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    M        -0.674  -0.676  -0.528  -0.810  -0.819  -0.601  -0.911  -0.911  -0.713
75    V        -1.808  -1.822  -1.664  -1.779  -1.785  -1.560  -1.435  -1.433  -1.236
76    T         1.212   1.224   1.288   1.224   1.245   1.339   1.291   1.309   1.404
77    P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
78    W         1.212   1.224   1.288   1.439   1.453   1.539   1.291   1.309   1.404
79    G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
80    T        -1.392  -1.359  -1.325  -1.243  -1.201  -1.150  -1.226  -1.196  -1.099
81    T         0.059   0.122   0.174  -0.140  -0.023   0.034  -0.282  -0.173  -0.124
82    S         0.555   0.448   0.293   0.563   0.420   0.162   0.557   0.389   0.098
83    S         0.555   0.633   0.315   0.571   0.673   0.220   0.557   0.669   0.137
84    P         0.555   0.633   0.315   0.620   0.722   0.264   0.557   0.669   0.137
85    V        -0.070  -0.088  -0.377   0.014  -0.015  -0.472  -0.072  -0.104  -0.506
86    T        -0.070  -0.250  -0.401   0.095  -0.144  -0.393  -0.072  -0.319  -0.540
87    I         0.555   0.608   0.308   0.600   0.671   0.235   0.557   0.633   0.124
88    S        -0.070  -0.250  -0.401   0.003  -0.247  -0.501  -0.072  -0.319  -0.540
89    Q        -1.506  -1.415  -1.343  -1.440  -1.317  -1.192  -1.331  -1.251  -1.115
90    F        -0.454  -0.350  -0.472  -0.524  -0.361  -0.556  -0.626  -0.486  -0.640
91    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   N        -1.506  -1.501  -1.352  -1.376  -1.354  -1.146  -1.331  -1.311  -1.120
104   S        -0.659  -0.644  -0.885  -0.528  -0.503  -0.865  -0.596  -0.584  -0.850
105   H        -0.357  -0.245  -0.437  -0.345  -0.193  -0.440  -0.492  -0.338  -0.593
106   F         0.555   0.473   0.295   0.710   0.611   0.354   0.557   0.428   0.101
107   H        -0.976  -1.062  -0.970  -0.970  -1.103  -0.993  -1.016  -1.084  -0.946
108   V         0.555   0.448   0.293   0.585   0.444   0.201   0.557   0.389   0.098
109   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
110   F         1.212   1.224   1.288   1.263   1.281   1.375   1.291   1.309   1.404
111   I         0.059   0.122   0.174  -0.255  -0.142  -0.072  -0.282  -0.173  -0.124
112   A         0.555   0.622   0.313   0.515   0.589   0.166   0.557   0.653   0.133
113   R         1.212   1.224   1.288   1.305   1.318   1.415   1.291   1.309   1.404
114   H         1.212   1.224   1.288   1.356   1.374   1.463   1.291   1.309   1.404
115   G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
116   I        -1.392  -1.261  -1.309  -1.432  -1.261  -1.304  -1.226  -1.107  -1.086
117   N        -1.392  -1.415  -1.325  -1.155  -1.190  -1.069  -1.226  -1.236  -1.099
118   H         1.212   1.224   1.288   1.356   1.374   1.463   1.291   1.309   1.404
119   E        -0.976  -1.062  -0.970  -0.973  -1.067  -0.922  -1.016  -1.084  -0.946
120   Y         0.004   0.025   0.142  -0.217  -0.184   0.002  -0.387  -0.357  -0.184
121   P        -1.090  -1.106  -0.983  -1.257  -1.272  -1.102  -1.121  -1.126  -0.959
122   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
123   T        -0.070  -0.085  -0.372   0.099   0.087  -0.339  -0.072  -0.099  -0.499
124   K        -1.090  -1.048  -0.981  -1.122  -1.075  -0.955  -1.121  -1.079  -0.957
125   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
126   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
127   F        -0.486  -0.507  -0.476  -0.646  -0.661  -0.621  -0.701  -0.705  -0.648
128   R         1.212   1.224   1.288   1.305   1.318   1.415   1.291   1.309   1.404
129   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
130   N         1.212   1.224   1.288   1.301   1.316   1.411   1.291   1.309   1.404
131   M         0.059   0.133   0.169  -0.098   0.027   0.070  -0.282  -0.152  -0.133
132   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
133   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
134   L         1.212   1.224   1.288   1.099   1.116   1.224   1.291   1.309   1.404
135   K         0.555   0.473   0.295   0.656   0.559   0.295   0.557   0.428   0.101
136   N        -1.506  -1.413  -1.350  -1.418  -1.309  -1.173  -1.331  -1.245  -1.120
137   L        -0.357  -0.367  -0.451  -0.492  -0.509  -0.643  -0.492  -0.508  -0.615
138   N        -0.357  -0.243  -0.438  -0.400  -0.236  -0.506  -0.492  -0.336  -0.593
139   C        -0.357  -0.250  -0.434  -0.325  -0.174  -0.424  -0.492  -0.341  -0.588
140   K        -0.659  -0.783  -0.906  -0.492  -0.675  -0.899  -0.596  -0.749  -0.874
141   A         0.555   0.473   0.295   0.525   0.411   0.161   0.557   0.428   0.101
142   V         0.232   0.314   0.233   0.127   0.261   0.099   0.033   0.168  -0.013
143   L        -0.674  -0.652  -0.521  -0.997  -0.955  -0.747  -0.911  -0.881  -0.704
144   S         0.004   0.025   0.142  -0.376  -0.348  -0.146  -0.387  -0.357  -0.184
145   F         1.212   1.224   1.288   1.263   1.281   1.375   1.291   1.309   1.404
146   S         1.212   1.224   1.288   1.153   1.174   1.274   1.291   1.309   1.404
147   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
148   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
149   G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
150   S         1.212   1.224   1.288   1.153   1.174   1.274   1.291   1.309   1.404
151   L         1.212   1.224   1.288   1.099   1.116   1.224   1.291   1.309   1.404
152   Q         0.232   0.137   0.172   0.356   0.188   0.207   0.033  -0.146  -0.126
153   P        -1.090  -0.967  -0.967  -1.081  -0.902  -0.877  -1.121  -0.981  -0.944
154   H        -0.357  -0.384  -0.432  -0.333  -0.352  -0.429  -0.492  -0.511  -0.585
155   I         1.212   1.224   1.288   1.181   1.201   1.299   1.291   1.309   1.404
156   K        -0.902  -0.929  -0.929  -0.852  -0.884  -0.910  -0.911  -0.926  -0.904
157   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
158   R        -0.070  -0.250  -0.401   0.179  -0.068  -0.320  -0.072  -0.319  -0.540
159   D         1.212   1.224   1.288   1.263   1.278   1.375   1.291   1.309   1.404
160   F         1.212   1.224   1.288   1.263   1.281   1.375   1.291   1.309   1.404
161   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
162   L        -0.357  -0.367  -0.451  -0.492  -0.509  -0.643  -0.492  -0.508  -0.615
163   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
164   Q        -0.486  -0.507  -0.476  -0.487  -0.496  -0.448  -0.701  -0.705  -0.648
165   Q         1.212   1.224   1.288   1.372   1.390   1.477   1.291   1.309   1.404
166   I         0.555   0.641   0.313   0.600   0.711   0.243   0.557   0.681   0.132
167   I         1.212   1.224   1.288   1.181   1.201   1.299   1.291   1.309   1.404
168   D         1.212   1.224   1.288   1.263   1.278   1.375   1.291   1.309   1.404
169   R         1.212   1.224   1.288   1.305   1.318   1.415   1.291   1.309   1.404
170   T         1.212   1.224   1.288   1.224   1.245   1.339   1.291   1.309   1.404
171   K         0.555   0.448   0.293   0.626   0.486   0.219   0.557   0.389   0.098
172   G         0.555   0.448   0.293   0.611   0.480   0.281   0.557   0.389   0.098
173   I         0.555   0.448   0.293   0.591   0.446   0.186   0.557   0.389   0.098
174   R         1.212   1.224   1.288   1.305   1.318   1.415   1.291   1.309   1.404
175   H        -0.659  -0.513  -0.888  -0.459  -0.264  -0.794  -0.596  -0.421  -0.854
176   S        -0.070  -0.250  -0.401   0.037  -0.195  -0.424  -0.072  -0.319  -0.540
177   S         0.004   0.029   0.143  -0.283  -0.231  -0.056  -0.387  -0.348  -0.182
178   Y         0.059   0.122   0.174  -0.013   0.092   0.156  -0.282  -0.173  -0.124
179   F         0.232   0.219   0.179   0.271   0.251   0.164   0.033   0.004  -0.114
180   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   D         0.059   0.122   0.174  -0.144  -0.032   0.033  -0.282  -0.173  -0.124
182   E        -0.976  -1.062  -0.970  -1.067  -1.176  -1.051  -1.016  -1.084  -0.946
183   G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
184   L        -0.976  -1.062  -0.970  -1.018  -1.104  -0.950  -1.016  -1.084  -0.946
185   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
186   G         0.059   0.076   0.159  -0.252  -0.234  -0.105  -0.282  -0.258  -0.151
187   H         1.212   1.224   1.288   1.356   1.374   1.463   1.291   1.309   1.404
188   V         0.232   0.328   0.241   0.088   0.242   0.071   0.033   0.192   0.002
189   G        -0.902  -0.886  -0.923  -0.891  -0.869  -0.930  -0.911  -0.880  -0.893
190   F         1.212   1.224   1.288   1.263   1.281   1.375   1.291   1.309   1.404
191   G         0.555   0.473   0.295   0.563   0.448   0.165   0.557   0.428   0.101
192   Q        -0.902  -0.865  -0.939  -0.824  -0.804  -0.843  -0.911  -0.897  -0.914
193   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
194   F         1.212   1.224   1.288   1.263   1.281   1.375   1.291   1.309   1.404
195   S         0.059   0.122   0.174  -0.124  -0.005   0.044  -0.282  -0.173  -0.124
196   Q        -1.808  -1.773  -1.649  -1.739  -1.676  -1.512  -1.435  -1.398  -1.226
197   K        -1.392  -1.448  -1.331  -1.411  -1.499  -1.336  -1.226  -1.267  -1.104
198   F         0.059   0.122   0.174  -0.210  -0.104  -0.026  -0.282  -0.173  -0.124
199   A        -0.902  -0.925  -0.942  -0.911  -0.934  -0.937  -0.911  -0.921  -0.914
200   E        -0.486  -0.534  -0.472  -0.591  -0.636  -0.524  -0.701  -0.749  -0.646
201   Y        -0.976  -1.062  -0.970  -1.003  -1.120  -0.992  -1.016  -1.084  -0.946
202   I        -0.357  -0.482  -0.470  -0.433  -0.635  -0.646  -0.492  -0.659  -0.640
203   Y        -1.392  -1.396  -1.342  -1.275  -1.308  -1.261  -1.226  -1.226  -1.112
204   Q        -1.392  -1.457  -1.351  -1.198  -1.297  -1.190  -1.226  -1.270  -1.120
205   F        -1.392  -1.326  -1.340  -1.181  -1.076  -1.119  -1.226  -1.172  -1.112
206   K        -1.392  -1.370  -1.342  -1.403  -1.410  -1.343  -1.226  -1.209  -1.113
207   N        -0.902  -0.857  -0.933  -0.833  -0.821  -0.891  -0.911  -0.889  -0.908
208   E        -2.110  -2.025  -1.906  -1.947  -1.822  -1.688  -1.540  -1.471  -1.304
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   I        -1.392  -1.333  -1.326  -1.329  -1.246  -1.193  -1.226  -1.166  -1.099
216   T        -1.392  -1.311  -1.337  -1.308  -1.210  -1.252  -1.226  -1.159  -1.109
217   N        -0.070  -0.085  -0.372   0.153   0.124  -0.321  -0.072  -0.099  -0.499
218   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   E        -1.489  -1.428  -1.351  -1.512  -1.413  -1.319  -1.311  -1.250  -1.120
222   E        -1.014  -0.967  -0.970  -1.107  -1.034  -1.025  -1.037  -0.978  -0.945
223   P        -1.489  -1.430  -1.349  -1.411  -1.330  -1.183  -1.311  -1.252  -1.118
224   C         0.039   0.049   0.151  -0.008  -0.001   0.135  -0.320  -0.309  -0.168
225   H        -1.506  -1.428  -1.346  -1.519  -1.410  -1.273  -1.331  -1.259  -1.117
226   L        -0.070  -0.002  -0.370  -0.037   0.050  -0.465  -0.072   0.016  -0.496
227   H         1.212   1.224   1.288   1.356   1.374   1.463   1.291   1.309   1.404
228   Y        -1.392  -1.323  -1.326  -1.216  -1.113  -1.125  -1.226  -1.153  -1.099
229   -         1.212   1.224   1.288   1.220   1.243   1.336   1.291   1.309   1.404
230   -        -1.110  -1.103  -0.986  -1.317  -1.310  -1.113  -1.125  -1.120  -0.960
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   D        -0.454  -0.350  -0.472  -0.509  -0.357  -0.525  -0.626  -0.486  -0.640
236   K        -1.014  -1.037  -0.963  -1.026  -1.045  -0.927  -1.037  -1.054  -0.936
237   D         0.497   0.547   0.278   0.611   0.677   0.262   0.469   0.543   0.071
238   M        -0.176  -0.057  -0.400  -0.171  -0.015  -0.490  -0.216  -0.056  -0.538
239   T         1.212   1.224   1.288   1.224   1.245   1.339   1.291   1.309   1.404
240   V        -0.600  -0.574  -0.512  -0.840  -0.797  -0.729  -0.806  -0.773  -0.692
241   V         0.004   0.026   0.143  -0.307  -0.269  -0.081  -0.387  -0.354  -0.183
242   C         1.212   1.224   1.288   1.424   1.439   1.526   1.291   1.309   1.404
243   M         1.212   1.224   1.288   1.337   1.354   1.445   1.291   1.309   1.404
244   E         1.212   1.224   1.288   1.175   1.197   1.294   1.291   1.309   1.404
245   G         1.212   1.224   1.288   1.153   1.167   1.274   1.291   1.309   1.404
246   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
247   Q         0.059   0.033   0.143  -0.056  -0.151   0.012  -0.282  -0.342  -0.183
248   F         1.212   1.224   1.288   1.263   1.281   1.375   1.291   1.309   1.404
249   S         1.212   1.224   1.288   1.153   1.174   1.274   1.291   1.309   1.404
250   T         1.212   1.224   1.288   1.224   1.245   1.339   1.291   1.309   1.404
251   R         1.212   1.224   1.288   1.305   1.318   1.415   1.291   1.309   1.404
252   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
253   E         1.212   1.224   1.288   1.175   1.197   1.294   1.291   1.309   1.404
254   S         1.212   1.224   1.288   1.153   1.174   1.274   1.291   1.309   1.404
255   K        -1.204  -1.294  -1.314  -0.895  -1.014  -1.029  -1.016  -1.111  -1.086
256   M         0.004   0.025   0.142  -0.237  -0.206  -0.017  -0.387  -0.356  -0.184
257   Y         1.212   1.224   1.288   1.364   1.381   1.470   1.291   1.309   1.404
258   R         1.212   1.224   1.288   1.305   1.318   1.415   1.291   1.309   1.404
259   M        -0.357  -0.243  -0.438  -0.437  -0.263  -0.547  -0.492  -0.336  -0.593
260   F        -0.659  -0.513  -0.888  -0.248  -0.052  -0.645  -0.596  -0.421  -0.854
261   G         0.555   0.554   0.300   0.592   0.590   0.246   0.557   0.553   0.109
262   G         0.555   0.448   0.293   0.563   0.412   0.162   0.557   0.389   0.098
263   H        -0.902  -0.813  -0.933  -0.893  -0.765  -0.927  -0.911  -0.802  -0.906
264   V         0.555   0.448   0.293   0.585   0.444   0.201   0.557   0.389   0.098
265   I         1.212   1.224   1.288   1.181   1.201   1.299   1.291   1.309   1.404
266   N         1.212   1.224   1.288   1.301   1.316   1.411   1.291   1.309   1.404
267   M         1.212   1.224   1.288   1.337   1.354   1.445   1.291   1.309   1.404
268   S         1.212   1.224   1.288   1.153   1.174   1.274   1.291   1.309   1.404
269   V        -0.357  -0.330  -0.451  -0.411  -0.417  -0.540  -0.492  -0.482  -0.615
270   I         0.059   0.084   0.161  -0.226  -0.180  -0.077  -0.282  -0.244  -0.147
271   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
272   E         1.212   1.224   1.288   1.175   1.197   1.294   1.291   1.309   1.404
273   A         0.555   0.554   0.300   0.515   0.505   0.143   0.557   0.553   0.109
274   K         1.212   1.224   1.288   1.216   1.238   1.332   1.291   1.309   1.404
275   L         1.212   1.224   1.288   1.099   1.116   1.224   1.291   1.309   1.404
276   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
277   R         0.555   0.554   0.300   0.732   0.729   0.349   0.557   0.553   0.109
278   E         1.212   1.224   1.288   1.175   1.197   1.294   1.291   1.309   1.404
279   C         0.059   0.122   0.174  -0.123  -0.040   0.061  -0.282  -0.173  -0.124
280   E         1.212   1.224   1.288   1.175   1.197   1.294   1.291   1.309   1.404
281   L         0.059   0.078   0.155  -0.226  -0.193  -0.093  -0.282  -0.255  -0.160
282   P        -0.357  -0.250  -0.434  -0.498  -0.341  -0.626  -0.492  -0.341  -0.588
283   Y         1.212   1.224   1.288   1.364   1.381   1.470   1.291   1.309   1.404
284   Q         1.212   1.224   1.288   1.372   1.390   1.477   1.291   1.309   1.404
285   M         1.212   1.224   1.288   1.337   1.354   1.445   1.291   1.309   1.404
286   I         0.059   0.066   0.153  -0.192  -0.183  -0.059  -0.282  -0.277  -0.163
287   C         1.212   1.224   1.288   1.424   1.439   1.526   1.291   1.309   1.404
288   M         1.212   1.224   1.288   1.337   1.354   1.445   1.291   1.309   1.404
289   S         0.232   0.137   0.172   0.078  -0.105  -0.076   0.033  -0.146  -0.126
290   T         1.212   1.224   1.288   1.224   1.245   1.339   1.291   1.309   1.404
291   D         1.212   1.224   1.288   1.263   1.278   1.375   1.291   1.309   1.404
292   Y         1.212   1.224   1.288   1.364   1.381   1.470   1.291   1.309   1.404
293   D         1.212   1.224   1.288   1.263   1.278   1.375   1.291   1.309   1.404
294   A        -0.600  -0.593  -0.503  -0.764  -0.737  -0.590  -0.806  -0.806  -0.681
295   W         1.212   1.224   1.288   1.439   1.453   1.539   1.291   1.309   1.404
296   R        -0.600  -0.511  -0.486  -0.616  -0.473  -0.471  -0.806  -0.685  -0.658
297   D        -0.486  -0.530  -0.476  -0.560  -0.591  -0.503  -0.701  -0.735  -0.649
298   E        -0.902  -0.900  -0.944  -0.874  -0.858  -0.928  -0.911  -0.904  -0.918
299   A         0.232   0.223   0.180   0.100   0.079  -0.043   0.033   0.010  -0.112
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   E         1.212   1.224   1.288   1.175   1.197   1.294   1.291   1.309   1.404
302   P         0.555   0.473   0.295   0.636   0.536   0.268   0.557   0.428   0.101
303   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
304   T        -0.070  -0.107  -0.382   0.083   0.038  -0.388  -0.072  -0.128  -0.512
305   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
306   E        -0.070  -0.107  -0.382   0.044  -0.013  -0.409  -0.072  -0.128  -0.512
307   T        -0.070  -0.156  -0.394   0.132   0.028  -0.303  -0.072  -0.192  -0.530
308   V         1.212   1.224   1.288   1.163   1.180   1.283   1.291   1.309   1.404
309   I        -0.674  -0.676  -0.528  -0.868  -0.848  -0.622  -0.911  -0.911  -0.713
310   G        -1.204  -1.310  -1.316  -1.071  -1.244  -1.259  -1.016  -1.126  -1.088
311   N        -0.357  -0.450  -0.457  -0.197  -0.325  -0.339  -0.492  -0.615  -0.623
312   L        -0.070  -0.250  -0.401  -0.024  -0.263  -0.485  -0.072  -0.319  -0.540
313   T        -1.392  -1.429  -1.334  -1.322  -1.385  -1.241  -1.226  -1.246  -1.105
314   N         0.004   0.025   0.142  -0.265  -0.241  -0.043  -0.387  -0.357  -0.184
315   N         1.212   1.224   1.288   1.301   1.316   1.411   1.291   1.309   1.404
316   G        -1.090  -1.093  -0.969  -1.304  -1.295  -1.110  -1.121  -1.108  -0.945
317   R        -1.808  -1.749  -1.654  -1.715  -1.631  -1.454  -1.435  -1.381  -1.229
318   N         0.555   0.554   0.300   0.719   0.718   0.324   0.557   0.553   0.109
319   A         1.212   1.224   1.288   1.097   1.103   1.222   1.291   1.309   1.404
320   N        -1.090  -1.071  -0.982  -0.988  -0.980  -0.846  -1.121  -1.097  -0.958
321   I        -1.506  -1.453  -1.342  -1.470  -1.385  -1.235  -1.331  -1.278  -1.113
322   L        -0.659  -0.693  -0.894  -0.567  -0.622  -0.894  -0.596  -0.644  -0.860
323   A        -0.357  -0.482  -0.470  -0.513  -0.725  -0.709  -0.492  -0.659  -0.640
324   S        -1.694  -1.712  -1.654  -1.663  -1.722  -1.661  -1.331  -1.345  -1.229
325   K        -1.392  -1.393  -1.333  -1.315  -1.356  -1.206  -1.226  -1.227  -1.105
326   I        -1.090  -1.114  -0.980  -1.330  -1.368  -1.156  -1.121  -1.132  -0.956
327   I        -0.600  -0.632  -0.520  -0.833  -0.904  -0.742  -0.806  -0.853  -0.702
328   V        -1.392  -1.368  -1.332  -1.353  -1.314  -1.298  -1.226  -1.198  -1.105
329   S        -1.489  -1.488  -1.346  -1.550  -1.532  -1.330  -1.311  -1.298  -1.115
330   M        -0.538  -0.492  -0.479  -0.679  -0.622  -0.589  -0.763  -0.696  -0.652
331   A        -0.454  -0.532  -0.481  -0.664  -0.805  -0.720  -0.626  -0.732  -0.655
332   K        -0.799  -0.786  -0.907  -0.623  -0.623  -0.793  -0.763  -0.754  -0.875
333   E        -0.902  -0.990  -0.948  -0.859  -0.982  -0.927  -0.911  -1.006  -0.924
334   I        -0.902  -0.853  -0.919  -0.946  -0.863  -0.951  -0.911  -0.844  -0.889
335   P        -1.392  -1.429  -1.346  -1.407  -1.471  -1.342  -1.226  -1.252  -1.116
336   E        -1.392  -1.407  -1.342  -1.368  -1.372  -1.278  -1.226  -1.235  -1.113
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   F        -0.954  -0.966  -0.978  -0.896  -0.922  -0.990  -0.946  -0.967  -0.951
339   M        -1.090  -1.090  -0.983  -1.156  -1.176  -1.027  -1.121  -1.116  -0.960
340   H        -2.110  -2.033  -1.905  -1.915  -1.808  -1.629  -1.540  -1.477  -1.304
341   T        -1.090  -1.001  -0.960  -1.242  -1.109  -1.020  -1.121  -1.020  -0.935
342   G         0.555   0.473   0.295   0.563   0.448   0.165   0.557   0.428   0.101
343   D        -0.902  -0.985  -0.949  -0.768  -0.884  -0.823  -0.911  -0.998  -0.924
344   G        -0.976  -1.062  -0.970  -0.998  -1.096  -0.949  -1.016  -1.084  -0.946
345   L         0.555   0.473   0.295   0.559   0.464   0.243   0.557   0.428   0.101
346   R        -1.090  -1.067  -0.977  -0.986  -0.945  -0.830  -1.121  -1.090  -0.954
347   G        -0.659  -0.664  -0.887  -0.519  -0.542  -0.852  -0.596  -0.610  -0.853
348   S         0.555   0.608   0.308   0.563   0.635   0.188   0.557   0.633   0.124
349   I        -0.902  -0.929  -0.938  -0.811  -0.883  -0.924  -0.911  -0.947  -0.914
350   K         0.232   0.137   0.172   0.229   0.082   0.122   0.033  -0.146  -0.126
351   K        -1.694  -1.725  -1.640  -1.314  -1.384  -1.290  -1.331  -1.355  -1.219
352   S        -0.486  -0.551  -0.476  -0.739  -0.836  -0.704  -0.701  -0.768  -0.651
353   I         0.004   0.025   0.142  -0.307  -0.271  -0.082  -0.387  -0.357  -0.184
354   S        -0.070  -0.250  -0.401   0.042  -0.187  -0.414  -0.072  -0.319  -0.540
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   T         1.212   1.224   1.288   1.224   1.245   1.339   1.291   1.309   1.404
358   K        -0.902  -0.925  -0.942  -0.899  -0.905  -0.967  -0.911  -0.921  -0.914
359   P         0.555   0.448   0.293   0.650   0.522   0.299   0.557   0.389   0.098
360   E        -1.204  -1.181  -1.307  -1.002  -0.988  -1.154  -1.016  -0.996  -1.080
361   A        -0.486  -0.536  -0.467  -0.695  -0.745  -0.612  -0.701  -0.745  -0.640
362   M        -0.674  -0.600  -0.503  -0.745  -0.625  -0.496  -0.911  -0.816  -0.681
363   S        -1.090  -1.114  -0.984  -1.161  -1.170  -0.971  -1.121  -1.133  -0.959
364   K        -0.902  -0.924  -0.949  -0.860  -0.924  -0.935  -0.911  -0.953  -0.925
365   E        -0.357  -0.392  -0.454  -0.376  -0.430  -0.524  -0.492  -0.547  -0.620
366   T        -1.090  -0.982  -0.959  -1.307  -1.151  -1.105  -1.121  -1.002  -0.933
367   L        -0.659  -0.824  -0.921  -0.597  -0.834  -0.991  -0.596  -0.795  -0.890
368   E        -1.392  -1.393  -1.333  -1.341  -1.341  -1.242  -1.226  -1.227  -1.105
369   R        -0.486  -0.489  -0.467  -0.526  -0.524  -0.460  -0.701  -0.707  -0.641
370   L        -0.357  -0.352  -0.429  -0.430  -0.412  -0.530  -0.492  -0.466  -0.581
371   R        -1.808  -1.829  -1.666  -1.496  -1.522  -1.316  -1.435  -1.437  -1.237
372   Y         0.232   0.314   0.233   0.271   0.395   0.255   0.033   0.168  -0.013
373   L         1.212   1.224   1.288   1.099   1.116   1.224   1.291   1.309   1.404
374   F         0.555   0.554   0.300   0.710   0.712   0.361   0.557   0.553   0.109
375   P         1.212   1.224   1.288   1.202   1.223   1.319   1.291   1.309   1.404
376   N        -0.486  -0.432  -0.474  -0.587  -0.523  -0.529  -0.701  -0.644  -0.648
377   Y        -0.659  -0.783  -0.906  -0.317  -0.511  -0.726  -0.596  -0.749  -0.874
378   W         0.555   0.448   0.293   0.866   0.724   0.458   0.557   0.389   0.098
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q07938
Output conservation file - output/Q07938
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
