1     M         0.955   0.974   1.024   1.135   1.159   1.218   1.001   1.024   1.094
2     S         0.955   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
3     T         0.003   0.105  -0.225   0.133   0.264  -0.215  -0.042   0.106  -0.411
4     D        -1.182  -1.111  -1.081  -1.240  -1.150  -1.077  -1.294  -1.210  -1.103
5     K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
6     I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
7     T         0.003   0.120  -0.222   0.133   0.283  -0.211  -0.042   0.127  -0.407
8     F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
9     L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
10    L        -0.878  -1.076  -1.070  -0.951  -1.239  -1.213  -0.877  -1.119  -1.087
11    N         0.955   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
12    W         0.955   0.974   1.024   1.205   1.229   1.280   1.001   1.024   1.094
13    Q        -1.182  -1.230  -1.088  -1.137  -1.221  -0.986  -1.294  -1.328  -1.110
14    P        -0.390  -0.244  -0.277  -0.559  -0.322  -0.381  -0.668  -0.424  -0.500
15    T        -0.390  -0.301  -0.296  -0.520  -0.370  -0.398  -0.668  -0.518  -0.531
16    P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
17    Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
18    H         0.955   0.974   1.024   1.178   1.200   1.256   1.001   1.024   1.094
19    I        -1.670  -1.753  -1.649  -1.661  -1.843  -1.664  -1.503  -1.574  -1.394
20    P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
21    I        -1.182  -1.178  -1.080  -1.341  -1.340  -1.190  -1.294  -1.257  -1.100
22    F        -0.390  -0.387  -0.313  -0.452  -0.450  -0.350  -0.668  -0.664  -0.561
23    L         0.003   0.120  -0.222  -0.123   0.040  -0.446  -0.042   0.127  -0.407
24    A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
25    Q        -0.878  -0.734  -1.032  -0.600  -0.405  -0.854  -0.877  -0.683  -1.040
26    T        -1.670  -1.611  -1.630  -1.480  -1.419  -1.447  -1.503  -1.422  -1.377
27    K         0.003  -0.152  -0.245  -0.054  -0.248  -0.379  -0.042  -0.277  -0.445
28    G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
29    Y        -0.390  -0.370  -0.311  -0.452  -0.419  -0.346  -0.668  -0.634  -0.556
30    F        -0.390  -0.404  -0.316  -0.430  -0.469  -0.349  -0.668  -0.693  -0.565
31    K         0.003  -0.152  -0.245  -0.096  -0.304  -0.471  -0.042  -0.277  -0.445
32    E        -0.878  -0.954  -1.051  -0.816  -0.928  -1.060  -0.877  -0.971  -1.063
33    Q        -0.510  -0.471  -0.322  -0.727  -0.673  -0.425  -0.877  -0.809  -0.577
34    G         0.003   0.080  -0.226   0.011   0.106  -0.298  -0.042   0.071  -0.413
35    L        -1.182  -1.012  -1.067  -1.406  -1.128  -1.193  -1.294  -1.063  -1.085
36    D        -0.878  -1.076  -1.070  -0.775  -1.079  -1.072  -0.877  -1.119  -1.087
37    I        -0.510  -0.449  -0.314  -0.774  -0.663  -0.442  -0.877  -0.770  -0.563
38    A         0.003   0.120  -0.222   0.032   0.186  -0.293  -0.042   0.127  -0.407
39    I         0.003  -0.075  -0.240  -0.013  -0.136  -0.427  -0.042  -0.158  -0.437
40    L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
41    E         0.955   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
42    P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
43    T        -1.182  -1.222  -1.087  -1.160  -1.219  -1.000  -1.294  -1.317  -1.109
44    N         0.003  -0.075  -0.240   0.189   0.073  -0.219  -0.042  -0.158  -0.437
45    P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
46    S         0.955   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
47    D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
48    V         0.955   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
49    T         0.955   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
50    E         0.003  -0.152  -0.245  -0.013  -0.237  -0.398  -0.042  -0.277  -0.445
51    L         0.003  -0.075  -0.240  -0.123  -0.226  -0.477  -0.042  -0.158  -0.437
52    I         0.003   0.080  -0.226   0.032   0.128  -0.303  -0.042   0.071  -0.413
53    G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
54    S         0.955   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
55    G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
56    K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
57    V         0.003   0.120  -0.222   0.104   0.260  -0.262  -0.042   0.127  -0.407
58    D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
59    M         0.003  -0.075  -0.240   0.227   0.106  -0.233  -0.042  -0.158  -0.437
60    G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
61    L         0.003  -0.075  -0.240  -0.092  -0.188  -0.410  -0.042  -0.158  -0.437
62    K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
63    A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
64    M         0.955   0.974   1.024   1.135   1.159   1.218   1.001   1.024   1.094
65    I        -0.390  -0.293  -0.291  -0.568  -0.417  -0.414  -0.668  -0.506  -0.523
66    H         0.955   0.974   1.024   1.178   1.200   1.256   1.001   1.024   1.094
67    T         0.955   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
68    L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
69    A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
70    A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
71    K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
72    A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
73    R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
74    G         0.003  -0.075  -0.240   0.011  -0.097  -0.321  -0.042  -0.158  -0.437
75    F        -1.182  -1.027  -1.065  -1.225  -0.968  -1.068  -1.294  -1.074  -1.081
76    P         0.003   0.105  -0.225   0.134   0.270  -0.234  -0.042   0.106  -0.411
77    V         0.955   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
78    T         0.003  -0.075  -0.240   0.086  -0.033  -0.347  -0.042  -0.158  -0.437
79    S         0.955   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
80    V        -1.182  -1.193  -1.077  -1.261  -1.261  -1.066  -1.294  -1.269  -1.096
81    A        -0.390  -0.252  -0.280  -0.646  -0.418  -0.472  -0.668  -0.438  -0.505
82    S         0.955   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
83    L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
84    L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
85    D         0.003  -0.152  -0.245   0.076  -0.138  -0.277  -0.042  -0.277  -0.445
86    E         0.955   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
87    P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
88    F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
89    T         0.955   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
90    G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
91    V        -0.878  -0.954  -1.051  -0.785  -0.930  -1.123  -0.877  -0.971  -1.063
92    L        -1.670  -1.767  -1.649  -1.673  -1.827  -1.584  -1.503  -1.587  -1.395
93    Y         0.003  -0.152  -0.245   0.132  -0.080  -0.254  -0.042  -0.277  -0.445
94    L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
95    K        -0.510  -0.459  -0.319  -0.938  -0.842  -0.603  -0.877  -0.789  -0.570
96    G         0.003  -0.075  -0.240  -0.029  -0.145  -0.409  -0.042  -0.158  -0.437
97    S         0.003  -0.152  -0.245   0.154  -0.060  -0.216  -0.042  -0.277  -0.445
98    G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
99    I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
100   T         0.955   0.974   1.024   0.998   1.024   1.097   1.001   1.024   1.094
101   E        -2.343  -2.293  -2.096  -2.089  -2.023  -1.744  -1.920  -1.850  -1.575
102   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
103   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
104   Q        -2.343  -2.317  -2.094  -2.064  -2.076  -1.738  -1.920  -1.867  -1.574
105   S         0.003  -0.152  -0.245   0.126  -0.100  -0.278  -0.042  -0.277  -0.445
106   L         0.003  -0.152  -0.245  -0.123  -0.341  -0.485  -0.042  -0.277  -0.445
107   K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
108   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
109   K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
110   K        -0.510  -0.444  -0.313  -0.787  -0.637  -0.437  -0.877  -0.762  -0.560
111   I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
112   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
113   Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
114   V         0.955   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
115   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
116   E         0.955   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
117   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
118   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
119   K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
120   I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
121   Q         0.955   0.974   1.024   1.074   1.101   1.164   1.001   1.024   1.094
122   I        -0.878  -0.954  -1.051  -0.852  -1.002  -1.149  -0.877  -0.971  -1.063
123   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
124   E         0.003  -0.152  -0.245  -0.007  -0.228  -0.384  -0.042  -0.277  -0.445
125   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
126   T         0.003  -0.152  -0.245   0.156  -0.055  -0.199  -0.042  -0.277  -0.445
127   K        -0.390  -0.454  -0.322  -0.655  -0.748  -0.522  -0.668  -0.779  -0.576
128   H         0.003  -0.152  -0.245   0.276   0.034  -0.195  -0.042  -0.277  -0.445
129   Y         0.003  -0.152  -0.245   0.141  -0.067  -0.233  -0.042  -0.277  -0.445
130   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
131   M        -0.390  -0.454  -0.322  -0.448  -0.626  -0.441  -0.668  -0.779  -0.576
132   K        -1.182  -1.198  -1.079  -1.297  -1.277  -1.119  -1.294  -1.276  -1.098
133   P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
134   E        -2.343  -2.293  -2.096  -2.248  -2.187  -1.890  -1.920  -1.850  -1.575
135   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
136   Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
137   T        -0.878  -0.734  -1.032  -0.728  -0.528  -0.998  -0.877  -0.683  -1.040
138   A         0.003   0.120  -0.222   0.034   0.187  -0.289  -0.042   0.127  -0.407
139   V         0.003  -0.152  -0.245   0.104  -0.126  -0.304  -0.042  -0.277  -0.445
140   R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
141   C         0.955   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
142   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
143   M         0.955   0.974   1.024   1.135   1.159   1.218   1.001   1.024   1.094
144   N         0.955   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
145   V         0.003  -0.152  -0.245   0.104  -0.126  -0.304  -0.042  -0.277  -0.445
146   A         0.003  -0.075  -0.240   0.032  -0.072  -0.322  -0.042  -0.158  -0.437
147   K         0.003  -0.152  -0.245  -0.067  -0.263  -0.406  -0.042  -0.277  -0.445
148   Y        -0.390  -0.454  -0.322  -0.520  -0.657  -0.456  -0.668  -0.779  -0.576
149   I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
150   I         0.003   0.080  -0.226  -0.013   0.088  -0.399  -0.042   0.071  -0.413
151   E        -0.878  -1.076  -1.070  -0.849  -1.142  -1.148  -0.877  -1.119  -1.087
152   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
153   K        -1.182  -1.146  -1.089  -1.430  -1.378  -1.232  -1.294  -1.247  -1.111
154   I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
155   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
156   A        -0.878  -0.954  -1.051  -0.797  -0.934  -1.050  -0.877  -0.971  -1.063
157   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
158   I         0.003   0.105  -0.225   0.032   0.159  -0.301  -0.042   0.106  -0.411
159   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
160   I         0.003  -0.075  -0.240  -0.013  -0.136  -0.427  -0.042  -0.158  -0.437
161   E         0.955   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
162   C         0.003  -0.075  -0.240   0.269   0.162  -0.117  -0.042  -0.158  -0.437
163   M        -1.182  -1.174  -1.079  -1.126  -1.098  -0.984  -1.294  -1.251  -1.099
164   Q         0.955   0.974   1.024   1.074   1.101   1.164   1.001   1.024   1.094
165   Q         0.003  -0.075  -0.240   0.239   0.137  -0.122  -0.042  -0.158  -0.437
166   V         0.955   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
167   E         0.003   0.105  -0.225   0.024   0.158  -0.284  -0.042   0.106  -0.411
168   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
169   E         0.955   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
170   E        -0.878  -0.921  -1.047  -0.816  -0.884  -1.054  -0.877  -0.933  -1.058
171   Y        -1.182  -1.146  -1.089  -1.097  -1.024  -0.954  -1.294  -1.247  -1.111
172   L         0.003  -0.152  -0.245  -0.076  -0.271  -0.381  -0.042  -0.277  -0.445
173   A        -1.855  -1.829  -1.652  -1.951  -1.901  -1.592  -1.711  -1.657  -1.398
174   K        -1.366  -1.276  -1.106  -1.659  -1.468  -1.226  -1.503  -1.372  -1.130
175   Q         0.003   0.105  -0.225   0.172   0.315  -0.237  -0.042   0.106  -0.411
176   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
177   R         0.003   0.080  -0.226   0.167   0.267  -0.243  -0.042   0.071  -0.413
178   P        -0.510  -0.474  -0.323  -0.735  -0.681  -0.430  -0.877  -0.814  -0.578
179   A        -2.831  -2.720  -2.458  -2.648  -2.486  -2.115  -2.129  -2.010  -1.692
180   S        -1.670  -1.611  -1.630  -1.524  -1.446  -1.513  -1.503  -1.422  -1.377
181   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
182   A        -0.390  -0.454  -0.322  -0.570  -0.689  -0.466  -0.668  -0.779  -0.576
183   K        -0.390  -0.454  -0.322  -0.621  -0.702  -0.476  -0.668  -0.779  -0.576
184   M         0.955   0.974   1.024   1.135   1.159   1.218   1.001   1.024   1.094
185   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
186   R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
187   I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
188   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
189   K        -1.182  -1.259  -1.091  -1.408  -1.487  -1.200  -1.294  -1.357  -1.113
190   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
191   A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
192   C        -1.182  -1.198  -1.079  -1.200  -1.210  -1.007  -1.294  -1.276  -1.098
193   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
194   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
195   C         0.955   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
196   C         0.955   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
197   C         0.955   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
198   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
199   C         0.955   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
200   T         0.003  -0.075  -0.240   0.133   0.024  -0.242  -0.042  -0.158  -0.437
201   V         0.003   0.177  -0.216   0.032   0.248  -0.286  -0.042   0.207  -0.396
202   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
203   Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
204   I         0.955   0.974   1.024   0.894   0.915   1.006   1.001   1.024   1.094
205   C        -1.182  -1.141  -1.070  -1.239  -1.183  -1.068  -1.294  -1.207  -1.088
206   N         0.003  -0.152  -0.245   0.240   0.029  -0.117  -0.042  -0.277  -0.445
207   D         0.003  -0.075  -0.240   0.037  -0.076  -0.356  -0.042  -0.158  -0.437
208   E        -1.182  -1.178  -1.080  -1.408  -1.369  -1.213  -1.294  -1.257  -1.100
209   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
210   L        -0.510  -0.444  -0.313  -0.942  -0.810  -0.582  -0.877  -0.762  -0.560
211   K        -1.182  -1.141  -1.070  -1.385  -1.274  -1.173  -1.294  -1.207  -1.088
212   K        -1.855  -1.801  -1.649  -1.999  -1.899  -1.643  -1.711  -1.630  -1.395
213   N         0.003  -0.152  -0.245   0.240   0.029  -0.117  -0.042  -0.277  -0.445
214   P         0.003   0.080  -0.226   0.150   0.252  -0.204  -0.042   0.071  -0.413
215   E        -1.855  -1.709  -1.649  -1.873  -1.653  -1.525  -1.711  -1.537  -1.395
216   K         0.003   0.080  -0.226  -0.091   0.033  -0.427  -0.042   0.071  -0.413
217   V         0.003  -0.152  -0.245   0.104  -0.126  -0.304  -0.042  -0.277  -0.445
218   R        -0.390  -0.349  -0.306  -0.623  -0.548  -0.466  -0.668  -0.598  -0.549
219   K        -0.390  -0.454  -0.322  -0.708  -0.818  -0.593  -0.668  -0.779  -0.576
220   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
221   L         0.003  -0.075  -0.240  -0.072  -0.162  -0.367  -0.042  -0.158  -0.437
222   K        -1.182  -1.131  -1.089  -1.293  -1.203  -1.077  -1.294  -1.234  -1.110
223   A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
224   I        -0.878  -0.856  -1.042  -0.795  -0.780  -1.033  -0.877  -0.844  -1.052
225   K         0.003  -0.152  -0.245  -0.031  -0.213  -0.329  -0.042  -0.277  -0.445
226   K        -1.182  -1.222  -1.083  -1.311  -1.348  -1.113  -1.294  -1.308  -1.104
227   A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
228   T         0.955   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
229   D         0.003  -0.152  -0.245   0.015  -0.223  -0.414  -0.042  -0.277  -0.445
230   Y        -1.670  -1.753  -1.649  -1.540  -1.678  -1.562  -1.503  -1.574  -1.394
231   V        -1.182  -1.111  -1.081  -1.143  -1.050  -0.990  -1.294  -1.210  -1.103
232   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
233   A        -0.878  -0.933  -1.049  -0.824  -0.934  -1.095  -0.877  -0.948  -1.061
234   D        -1.182  -1.174  -1.079  -1.122  -1.108  -0.942  -1.294  -1.251  -1.099
235   P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
236   V        -2.343  -2.234  -2.084  -2.239  -2.074  -1.880  -1.920  -1.795  -1.566
237   K        -1.670  -1.560  -1.621  -1.517  -1.353  -1.530  -1.503  -1.370  -1.369
238   A         0.003  -0.152  -0.245   0.030  -0.187  -0.334  -0.042  -0.277  -0.445
239   W         0.003  -0.152  -0.245   0.341   0.115  -0.089  -0.042  -0.277  -0.445
240   K        -0.878  -0.720  -1.030  -0.951  -0.710  -1.185  -0.877  -0.666  -1.038
241   E         0.003   0.105  -0.225  -0.007   0.132  -0.349  -0.042   0.106  -0.411
242   Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
243   I        -1.855  -1.740  -1.645  -1.882  -1.734  -1.559  -1.711  -1.579  -1.392
244   D        -0.878  -0.954  -1.051  -0.701  -0.807  -0.914  -0.877  -0.971  -1.063
245   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
246   K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
247   P         0.003  -0.152  -0.245   0.163  -0.053  -0.208  -0.042  -0.277  -0.445
248   Q        -1.670  -1.767  -1.649  -1.429  -1.619  -1.462  -1.503  -1.587  -1.395
249   L        -0.390  -0.252  -0.280  -0.448  -0.193  -0.323  -0.668  -0.438  -0.505
250   N        -1.855  -1.703  -1.649  -1.780  -1.604  -1.462  -1.711  -1.533  -1.395
251   N        -1.855  -1.697  -1.643  -1.759  -1.561  -1.441  -1.711  -1.544  -1.391
252   D        -1.182  -1.024  -1.067  -1.327  -1.083  -1.115  -1.294  -1.076  -1.085
253   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
254   S        -1.182  -1.198  -1.079  -1.072  -1.064  -0.893  -1.294  -1.276  -1.098
255   Y        -1.855  -1.703  -1.649  -1.712  -1.487  -1.407  -1.711  -1.533  -1.395
256   K         0.003  -0.152  -0.245  -0.096  -0.304  -0.471  -0.042  -0.277  -0.445
257   Q        -1.670  -1.601  -1.629  -1.436  -1.353  -1.434  -1.503  -1.411  -1.376
258   Y         0.003   0.177  -0.216   0.178   0.397  -0.165  -0.042   0.207  -0.396
259   Q        -0.510  -0.451  -0.315  -0.727  -0.648  -0.420  -0.877  -0.775  -0.565
260   R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
261   C         0.003  -0.075  -0.240   0.256   0.148  -0.144  -0.042  -0.158  -0.437
262   Y        -0.510  -0.472  -0.323  -0.662  -0.601  -0.364  -0.877  -0.812  -0.577
263   A         0.955   0.974   1.024   0.891   0.920   1.003   1.001   1.024   1.094
264   Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
265   F         0.955   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
266   S         0.955   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
267   S        -1.855  -1.819  -1.652  -1.804  -1.735  -1.475  -1.711  -1.647  -1.398
268   S        -0.390  -0.454  -0.322  -0.498  -0.640  -0.431  -0.668  -0.779  -0.576
269   L         0.003  -0.152  -0.245  -0.123  -0.341  -0.485  -0.042  -0.277  -0.445
270   Y        -0.878  -1.076  -1.070  -0.743  -1.042  -1.091  -0.877  -1.119  -1.087
271   N         0.955   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
272   V         0.955   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
273   H        -0.878  -1.076  -1.070  -0.544  -0.865  -0.927  -0.877  -1.119  -1.087
274   R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
275   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
276   W         0.955   0.974   1.024   1.205   1.229   1.280   1.001   1.024   1.094
277   K        -1.855  -1.898  -1.659  -1.822  -1.847  -1.494  -1.711  -1.712  -1.404
278   K         0.955   0.974   1.024   0.790   0.837   0.914   1.001   1.024   1.094
279   V         0.955   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
280   T         0.003   0.080  -0.226   0.146   0.244  -0.190  -0.042   0.071  -0.413
281   G        -1.855  -1.765  -1.646  -1.900  -1.759  -1.597  -1.711  -1.599  -1.393
282   Y         0.955   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
283   G         0.003  -0.152  -0.245  -0.002  -0.223  -0.358  -0.042  -0.277  -0.445
284   K         0.003  -0.075  -0.240  -0.053  -0.136  -0.369  -0.042  -0.158  -0.437
285   R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
286   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
287   A        -1.855  -1.665  -1.648  -1.988  -1.724  -1.662  -1.711  -1.506  -1.394
288   I         0.003  -0.075  -0.240   0.032  -0.081  -0.327  -0.042  -0.158  -0.437
289   L         0.003  -0.152  -0.245  -0.123  -0.341  -0.485  -0.042  -0.277  -0.445
290   P         0.003  -0.075  -0.240   0.150   0.043  -0.229  -0.042  -0.158  -0.437
291   P        -1.670  -1.659  -1.635  -1.460  -1.453  -1.439  -1.503  -1.478  -1.382
292   D         0.003   0.080  -0.226   0.076   0.176  -0.246  -0.042   0.071  -0.413
293   Y        -0.510  -0.449  -0.314  -0.662  -0.554  -0.346  -0.877  -0.770  -0.563
294   V        -1.855  -1.800  -1.648  -1.926  -1.840  -1.611  -1.711  -1.627  -1.395
295   S        -0.510  -0.444  -0.313  -0.678  -0.565  -0.360  -0.877  -0.762  -0.560
296   N         0.955   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
297   Y         0.003  -0.152  -0.245   0.156  -0.043  -0.199  -0.042  -0.277  -0.445
298   T         0.003   0.120  -0.222   0.133   0.283  -0.211  -0.042   0.127  -0.407
299   N         0.955   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
300   E         0.003  -0.152  -0.245  -0.020  -0.249  -0.414  -0.042  -0.277  -0.445
301   Y         0.003  -0.075  -0.240   0.141   0.044  -0.225  -0.042  -0.158  -0.437
302   L         0.955   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
303   S        -0.878  -1.076  -1.070  -0.705  -1.011  -1.031  -0.877  -1.119  -1.087
304   W         0.955   0.974   1.024   1.205   1.229   1.280   1.001   1.024   1.094
305   P        -1.182  -1.228  -1.088  -1.271  -1.362  -1.144  -1.294  -1.326  -1.110
306   E        -0.390  -0.454  -0.322  -0.697  -0.846  -0.624  -0.668  -0.779  -0.576
307   P        -0.878  -1.076  -1.070  -0.678  -0.980  -0.989  -0.877  -1.119  -1.087
308   E        -1.855  -1.671  -1.648  -1.935  -1.633  -1.596  -1.711  -1.510  -1.395
309   E         0.003  -0.152  -0.245  -0.007  -0.228  -0.384  -0.042  -0.277  -0.445
310   V        -0.878  -1.076  -1.070  -0.733  -1.044  -1.063  -0.877  -1.119  -1.087
311   S        -1.855  -1.829  -1.652  -1.920  -1.897  -1.626  -1.711  -1.657  -1.398
312   D         0.955   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
313   P         0.955   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
314   L        -1.855  -1.839  -1.652  -1.918  -1.843  -1.566  -1.711  -1.663  -1.398
315   E        -1.670  -1.428  -1.613  -1.724  -1.358  -1.668  -1.503  -1.220  -1.361
316   A        -0.878  -1.076  -1.070  -0.863  -1.180  -1.200  -0.877  -1.119  -1.087
317   Q         0.955   0.974   1.024   1.074   1.101   1.164   1.001   1.024   1.094
318   R        -2.343  -2.325  -2.098  -2.172  -2.212  -1.861  -1.920  -1.873  -1.577
319   L        -0.878  -1.076  -1.070  -0.932  -1.220  -1.177  -0.877  -1.119  -1.087
320   M        -0.390  -0.409  -0.317  -0.389  -0.452  -0.343  -0.668  -0.701  -0.567
321   A        -1.855  -1.807  -1.650  -2.075  -1.974  -1.726  -1.711  -1.635  -1.396
322   I        -1.855  -1.671  -1.648  -2.066  -1.777  -1.717  -1.711  -1.510  -1.395
323   H        -0.878  -1.076  -1.070  -0.596  -0.940  -1.025  -0.877  -1.119  -1.087
324   Q         0.955   0.974   1.024   1.074   1.101   1.164   1.001   1.024   1.094
325   E        -0.878  -1.076  -1.070  -0.885  -1.195  -1.216  -0.877  -1.119  -1.087
326   K        -1.670  -1.542  -1.624  -1.649  -1.450  -1.592  -1.503  -1.352  -1.371
327   C        -0.878  -1.076  -1.070  -0.602  -0.923  -0.968  -0.877  -1.119  -1.087
328   R        -1.182  -1.147  -1.074  -1.343  -1.279  -1.152  -1.294  -1.214  -1.092
329   Q        -2.343  -2.234  -2.084  -2.021  -1.862  -1.675  -1.920  -1.795  -1.566
330   E        -1.670  -1.593  -1.629  -1.421  -1.346  -1.442  -1.503  -1.413  -1.376
331   G         0.955   0.974   1.024   0.857   0.879   0.973   1.001   1.024   1.094
332   T         0.003   0.177  -0.216  -0.004   0.213  -0.313  -0.042   0.207  -0.396
333   F        -1.182  -1.222  -1.083  -1.150  -1.199  -1.002  -1.294  -1.308  -1.104
334   K        -1.855  -1.792  -1.647  -1.779  -1.655  -1.420  -1.711  -1.620  -1.394
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   R         0.955   0.974   1.024   1.069   1.087   1.160   1.001   1.024   1.094
341   L        -0.878  -0.933  -1.049  -0.927  -1.006  -1.142  -0.877  -0.948  -1.061
342   A        -1.855  -1.793  -1.648  -1.877  -1.763  -1.551  -1.711  -1.618  -1.394
343   L        -0.878  -0.921  -1.047  -0.959  -1.037  -1.194  -0.877  -0.933  -1.058
344   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   A        -1.670  -1.633  -1.629  -1.669  -1.651  -1.641  -1.503  -1.452  -1.376
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q07748
Output conservation file - output/Q07748
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
