1     M         1.327   1.369   1.436   1.512   1.590   1.666   1.424   1.486   1.595
2     K        -0.278  -0.379  -0.334  -0.151  -0.296  -0.320  -0.433  -0.556  -0.515
3     I        -0.597  -0.553  -0.418  -0.863  -0.810  -0.605  -0.859  -0.803  -0.626
4     V         1.327   1.369   1.436   1.177   1.240   1.352   1.424   1.486   1.595
5     L         0.260   0.337   0.322   0.089   0.219   0.128  -0.003   0.116   0.039
6     Q         1.327   1.369   1.436   1.415   1.483   1.575   1.424   1.486   1.595
7     K         0.260   0.237   0.292   0.046   0.011   0.111  -0.003  -0.070  -0.018
8     V         0.596   0.555   0.413   0.516   0.460   0.252   0.568   0.493   0.212
9     S        -0.463  -0.447  -0.380  -0.831  -0.810  -0.710  -0.716  -0.682  -0.580
10    Q        -0.950  -0.940  -0.865  -0.876  -0.869  -0.755  -1.002  -0.978  -0.867
11    A         0.596   0.555   0.413   0.695   0.638   0.390   0.568   0.493   0.212
12    S         0.596   0.698   0.424   0.666   0.812   0.433   0.568   0.718   0.233
13    V         1.327   1.369   1.436   1.177   1.240   1.352   1.424   1.486   1.595
14    V        -0.950  -0.884  -0.851  -1.092  -0.987  -0.988  -1.002  -0.916  -0.851
15    V         1.327   1.369   1.436   1.177   1.240   1.352   1.424   1.486   1.595
16    D        -0.278  -0.254  -0.329  -0.341  -0.362  -0.444  -0.433  -0.443  -0.511
17    S        -0.835  -0.648  -0.810  -0.803  -0.550  -0.759  -0.870  -0.657  -0.808
18    K        -0.587  -0.619  -0.777  -0.580  -0.650  -0.843  -0.542  -0.601  -0.763
19    V        -0.410  -0.479  -0.346  -0.654  -0.742  -0.564  -0.652  -0.705  -0.537
20    I        -0.278  -0.357  -0.316  -0.468  -0.605  -0.548  -0.433  -0.523  -0.488
21    S         0.655   0.467   0.444   0.747   0.523   0.479   0.660   0.345   0.269
22    S        -0.911  -0.974  -0.851  -0.902  -0.979  -0.797  -0.979  -1.018  -0.853
23    I         0.655   0.467   0.444   0.747   0.488   0.399   0.660   0.345   0.269
24    K        -1.762  -1.622  -1.560  -1.683  -1.435  -1.384  -1.417  -1.279  -1.165
25    H        -0.911  -0.974  -0.847  -0.900  -0.977  -0.781  -0.979  -1.019  -0.850
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    G         0.655   0.467   0.444   0.713   0.478   0.449   0.660   0.345   0.269
29    Y        -0.410  -0.496  -0.360  -0.430  -0.548  -0.368  -0.652  -0.732  -0.554
30    M        -0.461  -0.674  -0.798  -0.066  -0.376  -0.635  -0.389  -0.647  -0.787
31    L        -0.564  -0.520  -0.415  -0.976  -0.844  -0.729  -0.820  -0.757  -0.621
32    L         1.327   1.369   1.436   1.150   1.179   1.328   1.424   1.486   1.595
33    V        -0.461  -0.674  -0.798  -0.422  -0.663  -0.949  -0.389  -0.647  -0.787
34    G         0.705   0.561   0.453   0.744   0.535   0.395   0.734   0.502   0.285
35    I         0.192   0.159   0.265  -0.010  -0.040   0.022  -0.130  -0.220  -0.072
36    S        -1.010  -0.955  -0.844  -1.135  -1.048  -0.883  -1.079  -0.994  -0.847
37    I        -0.996  -1.137  -1.209  -0.597  -0.785  -0.896  -0.820  -0.968  -1.008
38    D        -1.388  -1.345  -1.234  -1.429  -1.446  -1.237  -1.252  -1.181  -1.034
39    D         1.327   1.369   1.436   1.288   1.328   1.456   1.424   1.486   1.595
40    S         0.108   0.185  -0.218   0.310   0.401  -0.210   0.129   0.232  -0.342
41    M        -2.041  -1.999  -1.836  -1.878  -1.877  -1.589  -1.511  -1.448  -1.256
42    A        -0.942  -0.841  -0.812  -0.997  -0.871  -0.834  -0.993  -0.847  -0.807
43    E         0.382   0.339   0.310   0.327   0.213   0.175   0.216   0.120   0.016
44    I        -0.564  -0.556  -0.422  -0.811  -0.757  -0.622  -0.820  -0.807  -0.630
45    D        -1.492  -1.356  -1.259  -1.468  -1.328  -1.124  -1.338  -1.203  -1.057
46    K         0.108  -0.027  -0.237   0.119  -0.067  -0.317   0.129  -0.065  -0.370
47    L         0.705   0.683   0.465   0.600   0.551   0.249   0.734   0.696   0.307
48    S        -0.186  -0.265  -0.334  -0.153  -0.255  -0.392  -0.302  -0.441  -0.516
49    K        -0.343  -0.442  -0.358  -0.501  -0.611  -0.463  -0.561  -0.669  -0.554
50    K         1.327   1.369   1.436   1.142   1.204   1.320   1.424   1.486   1.595
51    V        -0.632  -0.553  -0.402  -1.059  -0.851  -0.682  -0.907  -0.803  -0.606
52    L         0.382   0.286   0.308   0.187   0.007   0.051   0.216   0.022   0.013
53    S        -1.284  -1.159  -1.223  -1.350  -1.181  -1.217  -1.166  -1.015  -1.024
54    L         0.108   0.074  -0.227   0.129   0.047  -0.292   0.129   0.084  -0.356
55    R         0.192   0.159   0.265   0.139   0.008   0.131  -0.130  -0.220  -0.072
56    I        -0.942  -0.754  -0.808  -1.218  -0.910  -0.998  -0.993  -0.754  -0.803
57    F         0.382   0.286   0.308   0.603   0.427   0.462   0.216   0.022   0.013
58    E        -0.343  -0.383  -0.353  -0.377  -0.502  -0.372  -0.561  -0.616  -0.547
59    D        -0.461  -0.465  -0.757  -0.247  -0.276  -0.657  -0.389  -0.394  -0.739
60    E        -2.041  -1.970  -1.830  -2.064  -1.934  -1.745  -1.511  -1.425  -1.253
61    S        -0.721  -0.736  -0.822  -0.665  -0.643  -0.834  -0.734  -0.739  -0.820
62    R        -0.950  -0.735  -0.821  -0.906  -0.618  -0.676  -1.002  -0.723  -0.814
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    N        -1.284  -1.284  -1.234  -1.215  -1.190  -1.042  -1.166  -1.137  -1.033
76    L        -1.492  -1.528  -1.551  -0.988  -1.087  -1.163  -1.166  -1.191  -1.157
77    W         1.327   1.369   1.436   1.611   1.673   1.758   1.424   1.486   1.595
78    K         0.192   0.355   0.364  -0.144   0.107   0.129  -0.130   0.149   0.121
79    K        -0.996  -1.007  -1.188  -0.829  -0.834  -1.029  -0.820  -0.824  -0.987
80    N        -0.343  -0.373  -0.350  -0.338  -0.327  -0.310  -0.561  -0.599  -0.544
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    I        -0.186  -0.265  -0.334  -0.194  -0.302  -0.522  -0.302  -0.441  -0.516
83    K        -2.041  -1.978  -1.829  -2.089  -1.908  -1.790  -1.511  -1.430  -1.252
84    E         0.382   0.447   0.358   0.327   0.388   0.261   0.216   0.312   0.109
85    A        -0.839  -0.760  -0.828  -0.885  -0.706  -0.827  -0.907  -0.814  -0.832
86    N        -1.217  -1.209  -1.228  -1.022  -1.074  -1.077  -1.079  -1.074  -1.029
87    G         0.705   0.741   0.471   0.720   0.744   0.363   0.734   0.784   0.317
88    E         0.705   0.741   0.471   0.852   0.900   0.516   0.734   0.784   0.317
89    I         0.192   0.167   0.265  -0.010  -0.018   0.024  -0.130  -0.203  -0.071
90    L         1.327   1.369   1.436   1.150   1.179   1.328   1.424   1.486   1.595
91    S         0.102   0.150   0.271   0.030   0.182   0.322  -0.302  -0.236  -0.059
92    V         1.327   1.369   1.436   1.178   1.323   1.354   1.424   1.486   1.595
93    S         1.327   1.369   1.436   1.315   1.457   1.482   1.424   1.486   1.595
94    Q         1.327   1.369   1.436   1.430   1.524   1.589   1.424   1.486   1.595
95    F         1.327   1.369   1.436   1.508   1.553   1.662   1.424   1.486   1.595
96    T         1.327   1.369   1.436   1.396   1.446   1.557   1.424   1.486   1.595
97    L         1.327   1.369   1.436   1.150   1.179   1.328   1.424   1.486   1.595
98    M        -1.284  -1.368  -1.255  -0.887  -1.037  -0.866  -1.166  -1.205  -1.051
99    A         0.192   0.355   0.364   0.011   0.267   0.275  -0.130   0.149   0.121
100   K        -1.010  -1.032  -0.875  -1.012  -1.020  -0.850  -1.079  -1.069  -0.877
101   T        -0.393  -0.341  -0.347  -0.598  -0.464  -0.474  -0.648  -0.572  -0.540
102   K         0.108   0.077  -0.233   0.112   0.085  -0.328   0.129   0.087  -0.364
103   K         1.327   1.369   1.436   1.142   1.204   1.320   1.424   1.486   1.595
104   G         1.327   1.369   1.436   1.273   1.315   1.442   1.424   1.486   1.595
105   T        -0.996  -1.125  -1.210  -0.635  -0.848  -0.969  -0.820  -0.957  -1.009
106   K         1.327   1.369   1.436   1.142   1.204   1.320   1.424   1.486   1.595
107   P         1.327   1.369   1.436   1.545   1.591   1.697   1.424   1.486   1.595
108   D         1.327   1.369   1.436   1.288   1.328   1.456   1.424   1.486   1.595
109   F         1.327   1.369   1.436   1.508   1.553   1.662   1.424   1.486   1.595
110   H         1.327   1.369   1.436   1.585   1.662   1.734   1.424   1.486   1.595
111   L        -1.388  -1.429  -1.264  -1.374  -1.488  -1.233  -1.252  -1.255  -1.060
112   A         0.705   0.685   0.461   0.814   0.794   0.465   0.734   0.700   0.299
113   Q        -0.839  -0.928  -0.854  -0.795  -0.938  -0.805  -0.907  -0.969  -0.856
114   K         0.108  -0.037  -0.244   0.108  -0.099  -0.353   0.129  -0.078  -0.380
115   G         0.705   0.561   0.453   0.770   0.575   0.462   0.734   0.502   0.285
116   H        -1.388  -1.415  -1.267  -1.039  -1.135  -0.901  -1.252  -1.247  -1.063
117   I        -1.662  -1.634  -1.561  -1.330  -1.364  -1.283  -1.338  -1.292  -1.166
118   A         1.327   1.369   1.436   1.346   1.398   1.511   1.424   1.486   1.595
119   K        -1.937  -1.702  -1.791  -1.756  -1.417  -1.536  -1.425  -1.218  -1.226
120   E         0.108  -0.027  -0.237   0.334   0.143  -0.172   0.129  -0.065  -0.370
121   L         1.327   1.369   1.436   1.150   1.179   1.328   1.424   1.486   1.595
122   Y         1.327   1.369   1.436   1.585   1.657   1.734   1.424   1.486   1.595
123   E        -1.010  -0.925  -0.861  -1.001  -0.958  -0.815  -1.079  -0.964  -0.864
124   E        -0.942  -0.872  -0.826  -1.000  -0.872  -0.855  -0.993  -0.886  -0.823
125   F        -0.564  -0.495  -0.384  -0.779  -0.656  -0.513  -0.820  -0.720  -0.579
126   L        -0.461  -0.637  -0.782  -0.376  -0.620  -0.785  -0.389  -0.604  -0.769
127   K        -1.388  -1.268  -1.213  -1.478  -1.356  -1.196  -1.252  -1.106  -1.014
128   L        -1.010  -0.927  -0.858  -1.246  -1.157  -1.032  -1.079  -0.961  -0.858
129   L         0.108  -0.079  -0.254   0.075  -0.201  -0.461   0.129  -0.133  -0.394
130   R        -0.942  -0.973  -0.884  -0.854  -0.919  -0.851  -0.993  -1.017  -0.887
131   S        -1.217  -1.156  -1.218  -1.059  -1.022  -1.077  -1.079  -1.030  -1.021
132   D        -0.996  -0.952  -1.172  -0.811  -0.789  -1.102  -0.820  -0.767  -0.972
133   L         0.705   0.561   0.453   0.653   0.455   0.368   0.734   0.502   0.285
134   G         0.108  -0.079  -0.254   0.221  -0.075  -0.301   0.129  -0.133  -0.394
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   E        -1.388  -1.315  -1.223  -1.308  -1.229  -1.096  -1.252  -1.159  -1.025
137   E        -0.343  -0.348  -0.348  -0.425  -0.477  -0.447  -0.561  -0.557  -0.540
138   K         0.382   0.384   0.326   0.232   0.235   0.164   0.216   0.201   0.048
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   V         0.705   0.685   0.461   0.652   0.725   0.330   0.734   0.700   0.299
141   K         0.705   0.730   0.466   0.624   0.665   0.327   0.734   0.767   0.309
142   D        -0.186  -0.293  -0.338  -0.160  -0.361  -0.405  -0.302  -0.465  -0.523
143   G         1.327   1.369   1.436   1.273   1.315   1.442   1.424   1.486   1.595
144   E        -0.393  -0.259  -0.332  -0.595  -0.376  -0.464  -0.648  -0.470  -0.516
145   F         1.327   1.369   1.436   1.508   1.553   1.662   1.424   1.486   1.595
146   G         0.705   0.561   0.453   0.755   0.561   0.423   0.734   0.502   0.285
147   A         1.327   1.369   1.436   1.346   1.398   1.511   1.424   1.486   1.595
148   M         1.327   1.369   1.436   1.516   1.604   1.669   1.424   1.486   1.595
149   M         1.327   1.369   1.436   1.516   1.604   1.669   1.424   1.486   1.595
150   S        -0.839  -0.928  -0.854  -0.854  -0.923  -0.804  -0.907  -0.969  -0.856
151   C         0.192   0.274   0.301   0.029   0.210   0.206  -0.130   0.001  -0.001
152   S        -0.839  -0.824  -0.835  -0.886  -0.825  -0.879  -0.907  -0.865  -0.838
153   L         1.327   1.369   1.436   1.150   1.179   1.328   1.424   1.486   1.595
154   T         0.102   0.163   0.267  -0.234  -0.098   0.027  -0.302  -0.211  -0.068
155   N         1.327   1.369   1.436   1.527   1.586   1.679   1.424   1.486   1.595
156   E        -0.343  -0.317  -0.342  -0.414  -0.397  -0.361  -0.561  -0.506  -0.529
157   G         1.327   1.369   1.436   1.273   1.315   1.442   1.424   1.486   1.595
158   P         1.327   1.369   1.436   1.545   1.591   1.697   1.424   1.486   1.595
159   V         1.327   1.369   1.436   1.178   1.323   1.354   1.424   1.486   1.595
160   T         1.327   1.369   1.436   1.396   1.446   1.557   1.424   1.486   1.595
161   I         0.705   0.561   0.453   0.817   0.670   0.419   0.734   0.502   0.285
162   I        -1.217  -1.247  -1.216  -1.157  -1.107  -1.175  -1.079  -1.076  -1.014
163   L        -1.388  -1.412  -1.270  -1.132  -1.195  -1.020  -1.252  -1.243  -1.065
164   D         0.705   0.561   0.453   0.756   0.560   0.399   0.734   0.502   0.285
165   S        -0.343  -0.410  -0.355  -0.388  -0.452  -0.404  -0.561  -0.616  -0.546
166   D        -1.010  -0.928  -0.867  -1.156  -1.088  -0.953  -1.079  -0.984  -0.870
167   -        -0.367  -0.491  -0.409  -0.327  -0.535  -0.366  -0.534  -0.715  -0.613
168   -        -0.367  -0.491  -0.409  -0.415  -0.628  -0.560  -0.534  -0.715  -0.613
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   Q        -1.662  -1.697  -1.575  -1.740  -1.852  -1.608  -1.338  -1.341  -1.176
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q07648
Output conservation file - output/Q07648
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
