1     M         1.759   1.779   1.866   1.999   2.026   2.164   1.984   2.012   2.161
2     A        -0.600  -0.555  -0.601  -0.784  -0.732  -0.783  -0.675  -0.635  -0.648
3     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     S        -0.698  -0.654  -0.625  -0.801  -0.739  -0.693  -0.783  -0.733  -0.675
7     L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
8     D        -1.836  -1.810  -1.716  -1.719  -1.686  -1.542  -1.300  -1.273  -1.152
9     R        -1.470  -1.416  -1.391  -1.236  -1.180  -1.118  -1.144  -1.092  -1.027
10    L         1.002   1.016   0.861   0.997   1.017   0.814   1.045   1.066   0.769
11    R         0.654   0.651   0.650   0.572   0.558   0.506   0.420   0.406   0.354
12    E        -0.096  -0.118  -0.063  -0.375  -0.404  -0.312  -0.362  -0.380  -0.297
13    H        -1.470  -1.416  -1.391  -1.198  -1.148  -1.078  -1.144  -1.092  -1.027
14    L        -0.600  -0.602  -0.621  -0.708  -0.719  -0.728  -0.675  -0.682  -0.670
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    K        -0.966  -0.959  -1.002  -1.018  -1.000  -1.087  -0.831  -0.821  -0.840
19    N        -1.104  -1.146  -1.050  -1.191  -1.246  -1.105  -0.987  -1.015  -0.891
20    G        -1.104  -1.052  -1.036  -1.113  -1.048  -1.006  -0.987  -0.934  -0.879
21    D        -1.104  -1.086  -1.051  -1.194  -1.183  -1.105  -0.987  -0.966  -0.891
22    K        -1.470  -1.418  -1.388  -1.360  -1.278  -1.239  -1.144  -1.092  -1.025
23    L        -0.600  -0.598  -0.601  -0.696  -0.700  -0.681  -0.675  -0.669  -0.644
24    V        -1.104  -1.084  -1.036  -1.232  -1.213  -1.135  -0.987  -0.962  -0.879
25    L         1.002   1.016   0.861   0.997   1.017   0.814   1.045   1.066   0.769
26    K        -1.470  -1.414  -1.387  -1.486  -1.395  -1.365  -1.144  -1.088  -1.024
27    N        -0.966  -0.907  -1.003  -1.000  -0.911  -1.065  -0.831  -0.767  -0.841
28    N         0.004  -0.014  -0.041   0.031  -0.024  -0.084  -0.162  -0.197  -0.245
29    E        -0.702  -0.665  -0.637  -0.843  -0.809  -0.763  -0.775  -0.732  -0.683
30    G         0.835   0.742   0.738   0.922   0.769   0.742   0.758   0.579   0.532
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    Q        -0.109  -0.056  -0.066  -0.361  -0.289  -0.282  -0.358  -0.286  -0.294
35    S        -1.124  -1.119  -1.054  -1.216  -1.225  -1.137  -0.996  -0.987  -0.892
36    T         0.156   0.089   0.002   0.236   0.129  -0.027   0.068  -0.039  -0.179
37    D        -0.007   0.031  -0.037  -0.102  -0.074  -0.156  -0.206  -0.172  -0.252
38    D        -0.007  -0.059  -0.049  -0.187  -0.270  -0.280  -0.206  -0.270  -0.262
39    I         1.759   1.779   1.866   1.743   1.772   1.908   1.984   2.012   2.161
40    T        -1.470  -1.494  -1.414  -1.387  -1.430  -1.322  -1.144  -1.156  -1.046
41    K        -1.104  -1.020  -1.032  -1.191  -1.070  -1.087  -0.987  -0.907  -0.875
42    A         1.759   1.779   1.866   1.788   1.812   1.953   1.984   2.012   2.161
43    T        -0.966  -0.940  -0.983  -0.879  -0.829  -0.936  -0.831  -0.802  -0.820
44    M        -1.836  -1.810  -1.716  -1.440  -1.406  -1.264  -1.300  -1.273  -1.152
45    V        -0.007  -0.055  -0.051  -0.120  -0.197  -0.208  -0.206  -0.272  -0.272
46    E        -1.470  -1.469  -1.395  -1.373  -1.381  -1.286  -1.144  -1.136  -1.030
47    T        -0.372  -0.333  -0.499  -0.182  -0.127  -0.392  -0.362  -0.313  -0.514
48    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    G         0.720   0.671   0.698   0.719   0.631   0.650   0.547   0.445   0.451
53    S        -0.802  -0.778  -0.686  -1.040  -1.013  -0.866  -0.890  -0.859  -0.738
54    T        -1.470  -1.418  -1.388  -1.402  -1.302  -1.294  -1.144  -1.092  -1.025
55    Q        -1.470  -1.476  -1.394  -1.406  -1.430  -1.298  -1.144  -1.142  -1.030
56    D        -1.104  -1.133  -1.068  -1.093  -1.131  -1.039  -0.987  -1.005  -0.906
57    S        -1.470  -1.469  -1.395  -1.455  -1.430  -1.335  -1.144  -1.136  -1.030
58    F        -1.104  -1.087  -1.053  -1.004  -0.976  -0.954  -0.987  -0.966  -0.893
59    P        -0.600  -0.623  -0.607  -0.641  -0.686  -0.665  -0.675  -0.695  -0.651
60    L         1.002   0.922   0.835   0.984   0.876   0.749   1.045   0.906   0.720
61    N         0.288   0.308   0.097   0.357   0.374   0.062   0.263   0.287  -0.034
62    E         0.288   0.243   0.090   0.415   0.350   0.150   0.263   0.195  -0.044
63    E        -1.104  -1.119  -1.041  -1.086  -1.102  -0.981  -0.987  -0.994  -0.883
64    T         1.759   1.779   1.866   1.777   1.806   1.943   1.984   2.012   2.161
65    E        -0.600  -0.675  -0.629  -0.646  -0.758  -0.689  -0.675  -0.750  -0.677
66    I         0.288   0.308   0.097   0.461   0.486   0.167   0.263   0.287  -0.034
67    E        -0.738  -0.713  -0.652  -0.806  -0.770  -0.691  -0.831  -0.801  -0.704
68    I        -1.104  -1.087  -1.053  -1.151  -1.132  -1.092  -0.987  -0.966  -0.893
69    D        -0.007  -0.047  -0.044  -0.130  -0.192  -0.206  -0.206  -0.252  -0.260
70    G        -0.096  -0.069  -0.063  -0.220  -0.187  -0.159  -0.362  -0.328  -0.296
71    S        -0.966  -0.964  -1.002  -0.975  -0.970  -1.031  -0.831  -0.829  -0.840
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    L        -0.966  -0.957  -0.998  -0.681  -0.664  -0.738  -0.831  -0.820  -0.836
76    V        -0.600  -0.577  -0.602  -0.525  -0.474  -0.519  -0.675  -0.640  -0.646
77    Q        -1.470  -1.405  -1.386  -1.430  -1.338  -1.300  -1.144  -1.080  -1.024
78    L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
79    R         0.654   0.646   0.649   0.572   0.546   0.504   0.420   0.395   0.352
80    I        -0.600  -0.502  -0.579  -0.747  -0.596  -0.698  -0.675  -0.552  -0.619
81    I         0.654   0.746   0.711   0.514   0.667   0.588   0.420   0.587   0.477
82    V        -0.234  -0.232  -0.147  -0.365  -0.347  -0.233  -0.518  -0.517  -0.402
83    H        -0.600  -0.558  -0.597  -0.440  -0.382  -0.421  -0.675  -0.617  -0.640
84    C         1.002   0.922   0.835   1.344   1.238   1.104   1.045   0.906   0.720
85    W         1.002   1.016   0.861   1.305   1.326   1.127   1.045   1.066   0.769
86    M         0.288   0.308   0.097   0.362   0.375   0.111   0.263   0.287  -0.034
87    N        -0.372  -0.427  -0.526  -0.120  -0.225  -0.404  -0.362  -0.435  -0.547
88    K        -1.104  -1.102  -1.048  -1.133  -1.109  -1.029  -0.987  -0.976  -0.888
89    D        -0.600  -0.606  -0.601  -0.698  -0.702  -0.676  -0.675  -0.675  -0.644
90    S        -0.600  -0.666  -0.600  -0.756  -0.843  -0.744  -0.675  -0.737  -0.647
91    S         1.002   0.953   0.845   0.951   0.893   0.740   1.045   0.960   0.738
92    A         0.498   0.548   0.620   0.265   0.353   0.456   0.107   0.200   0.291
93    A         0.288   0.318   0.085   0.435   0.476   0.129   0.263   0.307  -0.052
94    D        -0.007  -0.055  -0.051  -0.085  -0.158  -0.152  -0.206  -0.272  -0.272
95    Y         1.759   1.779   1.866   1.921   1.949   2.086   1.984   2.012   2.161
96    L        -0.600  -0.675  -0.629  -0.793  -0.903  -0.834  -0.675  -0.750  -0.677
97    A        -0.600  -0.643  -0.620  -0.573  -0.637  -0.593  -0.675  -0.721  -0.669
98    D        -0.966  -1.036  -1.037  -0.817  -0.918  -0.919  -0.831  -0.901  -0.875
99    C         1.002   1.016   0.861   1.350   1.373   1.158   1.045   1.066   0.769
100   Q        -1.470  -1.494  -1.414  -1.318  -1.376  -1.264  -1.144  -1.156  -1.046
101   N        -1.470  -1.436  -1.391  -1.406  -1.358  -1.293  -1.144  -1.108  -1.027
102   K        -0.600  -0.631  -0.617  -0.733  -0.779  -0.722  -0.675  -0.709  -0.666
103   Q        -0.600  -0.490  -0.573  -0.551  -0.386  -0.512  -0.675  -0.547  -0.617
104   L         0.288   0.392   0.112   0.388   0.534   0.127   0.263   0.415  -0.010
105   T        -0.372  -0.419  -0.537  -0.160  -0.225  -0.395  -0.362  -0.422  -0.561
106   N        -0.372  -0.396  -0.528  -0.174  -0.202  -0.415  -0.362  -0.392  -0.550
107   V        -0.600  -0.577  -0.602  -0.615  -0.575  -0.625  -0.675  -0.640  -0.646
108   S        -0.372  -0.466  -0.536  -0.369  -0.501  -0.621  -0.362  -0.481  -0.560
109   F         1.759   1.779   1.866   1.820   1.849   1.986   1.984   2.012   2.161
110   L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
111   Q        -0.600  -0.623  -0.607  -0.514  -0.551  -0.511  -0.675  -0.695  -0.651
112   R         0.654   0.678   0.689   0.572   0.610   0.590   0.420   0.459   0.432
113   T        -0.007  -0.004  -0.017  -0.056  -0.039  -0.083  -0.206  -0.187  -0.215
114   D         0.654   0.678   0.689   0.506   0.540   0.537   0.420   0.459   0.432
115   L         1.002   0.953   0.845   0.981   0.915   0.758   1.045   0.960   0.738
116   I        -0.372  -0.292  -0.495  -0.299  -0.177  -0.515  -0.362  -0.257  -0.508
117   N        -1.104  -1.086  -1.051  -1.154  -1.139  -1.070  -0.987  -0.966  -0.891
118   W         1.759   1.779   1.866   1.962   1.988   2.127   1.984   2.012   2.161
119   L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
120   S        -0.966  -1.036  -1.037  -0.949  -1.062  -1.050  -0.831  -0.901  -0.875
121   G         1.759   1.779   1.866   1.826   1.854   1.992   1.984   2.012   2.161
122   N        -0.096  -0.137  -0.071  -0.265  -0.323  -0.225  -0.362  -0.403  -0.307
123   T         0.654   0.670   0.660   0.434   0.459   0.423   0.420   0.442   0.374
124   E         0.498   0.502   0.593   0.208   0.204   0.346   0.107   0.106   0.234
125   S         0.498   0.501   0.591   0.194   0.186   0.317   0.107   0.103   0.231
126   S        -0.600  -0.675  -0.629  -0.596  -0.695  -0.624  -0.675  -0.750  -0.677
127   Q        -1.470  -1.480  -1.412  -1.131  -1.140  -1.045  -1.144  -1.145  -1.044
128   Y        -0.600  -0.675  -0.629  -0.447  -0.562  -0.501  -0.675  -0.750  -0.677
129   L        -0.007   0.090  -0.016  -0.125   0.043  -0.142  -0.206  -0.055  -0.214
130   K        -0.966  -0.940  -0.983  -0.975  -0.931  -1.002  -0.831  -0.802  -0.820
131   A        -1.836  -1.810  -1.716  -1.721  -1.687  -1.545  -1.300  -1.273  -1.152
132   P        -0.966  -0.888  -0.997  -0.900  -0.779  -0.967  -0.831  -0.744  -0.835
133   G        -0.702  -0.692  -0.636  -0.672  -0.658  -0.586  -0.775  -0.760  -0.681
134   Q        -0.702  -0.662  -0.631  -0.742  -0.679  -0.637  -0.775  -0.724  -0.675
135   K         0.004  -0.028  -0.082  -0.176  -0.230  -0.321  -0.162  -0.211  -0.306
136   G        -0.702  -0.654  -0.661  -0.926  -0.858  -0.862  -0.775  -0.714  -0.710
137   E        -0.162  -0.180  -0.126  -0.392  -0.455  -0.376  -0.411  -0.443  -0.372
138   T        -0.162  -0.089  -0.101  -0.304  -0.175  -0.230  -0.411  -0.303  -0.334
139   S        -0.162  -0.186  -0.129  -0.355  -0.393  -0.286  -0.411  -0.451  -0.376
140   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   A         0.720   0.779   0.721   0.666   0.756   0.640   0.547   0.650   0.497
151   G        -0.162  -0.142  -0.102  -0.369  -0.342  -0.279  -0.411  -0.385  -0.336
152   E        -1.124  -1.137  -1.076  -1.240  -1.275  -1.194  -0.996  -1.003  -0.912
153   L        -0.536  -0.572  -0.587  -0.593  -0.642  -0.673  -0.571  -0.615  -0.622
154   S        -0.096  -0.030  -0.063  -0.412  -0.322  -0.329  -0.362  -0.281  -0.296
155   T        -1.104  -1.098  -1.041  -1.093  -1.069  -1.006  -0.987  -0.976  -0.883
156   V        -0.966  -0.990  -1.003  -0.884  -0.934  -0.958  -0.831  -0.856  -0.841
157   K        -0.109  -0.100  -0.065  -0.246  -0.218  -0.184  -0.358  -0.337  -0.292
158   S         0.583   0.590   0.629   0.227   0.236   0.267   0.281   0.285   0.311
159   T        -0.109  -0.103  -0.064  -0.202  -0.189  -0.136  -0.358  -0.342  -0.290
160   T        -0.536  -0.456  -0.552  -0.542  -0.416  -0.586  -0.571  -0.466  -0.580
161   S        -0.109  -0.140  -0.083  -0.426  -0.464  -0.384  -0.358  -0.394  -0.318
162   A         0.927   0.963   0.833   0.973   1.025   0.817   0.919   0.977   0.716
163   -        -0.802  -0.783  -0.686  -0.990  -0.948  -0.816  -0.890  -0.864  -0.738
164   S        -0.702  -0.644  -0.629  -0.780  -0.697  -0.662  -0.775  -0.702  -0.673
165   L         0.004  -0.039  -0.043   0.000  -0.063  -0.076  -0.162  -0.227  -0.248
166   E         0.004   0.036  -0.007  -0.058  -0.010  -0.089  -0.162  -0.114  -0.192
167   N        -0.702  -0.694  -0.634  -0.762  -0.747  -0.673  -0.775  -0.763  -0.679
168   D         0.516   0.564   0.632   0.176   0.272   0.358   0.145   0.232   0.316
169   S        -0.702  -0.728  -0.661  -0.951  -0.997  -0.901  -0.775  -0.802  -0.710
170   -         0.720   0.711   0.704   0.896   0.879   0.865   0.547   0.521   0.464
171   E         0.004  -0.009  -0.036  -0.171  -0.190  -0.254  -0.162  -0.183  -0.237
172   V        -0.190  -0.161  -0.120  -0.439  -0.397  -0.330  -0.468  -0.430  -0.366
173   S         0.156   0.140   0.032   0.110   0.078  -0.124   0.068   0.039  -0.132
174   D         0.927   0.865   0.796   0.906   0.812   0.688   0.919   0.806   0.645
175   P         0.288   0.241   0.073   0.521   0.448   0.202   0.263   0.190  -0.070
176   V        -0.600  -0.675  -0.629  -0.577  -0.678  -0.606  -0.675  -0.750  -0.677
177   V        -0.600  -0.566  -0.582  -0.761  -0.714  -0.738  -0.675  -0.636  -0.628
178   V        -1.470  -1.416  -1.391  -1.317  -1.242  -1.197  -1.144  -1.092  -1.027
179   E        -0.096  -0.133  -0.083  -0.156  -0.184  -0.087  -0.362  -0.396  -0.319
180   T        -0.966  -0.907  -1.003  -0.872  -0.795  -0.950  -0.831  -0.767  -0.841
181   M        -1.104  -1.057  -1.047  -1.060  -1.007  -0.945  -0.987  -0.940  -0.888
182   K        -1.104  -1.136  -1.039  -1.066  -1.111  -0.960  -0.987  -1.007  -0.881
183   H        -1.470  -1.477  -1.393  -1.219  -1.240  -1.122  -1.144  -1.143  -1.029
184   E         1.002   0.922   0.835   1.044   0.937   0.813   1.045   0.906   0.720
185   R         0.288   0.261   0.089   0.450   0.410   0.126   0.263   0.221  -0.046
186   I        -0.738  -0.753  -0.655  -0.843  -0.855  -0.703  -0.831  -0.835  -0.707
187   L        -1.104  -1.133  -1.068  -1.212  -1.243  -1.132  -0.987  -1.005  -0.906
188   V        -1.104  -1.136  -1.039  -1.128  -1.168  -1.027  -0.987  -1.007  -0.881
189   D         1.002   0.922   0.835   1.049   0.942   0.820   1.045   0.906   0.720
190   H         1.759   1.779   1.866   1.925   1.951   2.090   1.984   2.012   2.161
191   N         1.759   1.779   1.866   1.796   1.827   1.961   1.984   2.012   2.161
192   S         0.654   0.678   0.689   0.438   0.476   0.478   0.420   0.459   0.432
193   A        -0.600  -0.627  -0.598  -0.504  -0.545  -0.503  -0.675  -0.701  -0.645
194   L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
195   R         0.654   0.651   0.650   0.687   0.678   0.665   0.420   0.406   0.354
196   G         1.759   1.779   1.866   1.826   1.854   1.992   1.984   2.012   2.161
197   A        -0.372  -0.427  -0.526  -0.356  -0.440  -0.584  -0.362  -0.435  -0.547
198   K         1.759   1.779   1.866   1.615   1.645   1.781   1.984   2.012   2.161
199   P         0.654   0.678   0.689   0.661   0.698   0.693   0.420   0.459   0.432
200   I        -0.007   0.046  -0.030  -0.074  -0.006  -0.118  -0.206  -0.145  -0.242
201   N         0.654   0.722   0.702   0.534   0.642   0.594   0.420   0.543   0.458
202   F         1.759   1.779   1.866   1.820   1.849   1.986   1.984   2.012   2.161
203   G        -0.372  -0.459  -0.538  -0.179  -0.320  -0.456  -0.362  -0.473  -0.562
204   Y         0.654   0.594   0.639   0.658   0.529   0.561   0.420   0.293   0.330
205   L         1.002   0.953   0.845   0.981   0.915   0.758   1.045   0.960   0.738
206   I        -0.600  -0.675  -0.629  -0.600  -0.693  -0.616  -0.675  -0.750  -0.677
207   K         0.654   0.678   0.689   0.364   0.406   0.390   0.420   0.459   0.432
208   D         1.002   1.046   0.856   1.036   1.093   0.831   1.045   1.115   0.760
209   A         0.288   0.161   0.055   0.484   0.310   0.165   0.263   0.073  -0.098
210   E        -0.600  -0.675  -0.629  -0.708  -0.817  -0.738  -0.675  -0.750  -0.677
211   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   K         0.288   0.161   0.055   0.264   0.085  -0.082   0.263   0.073  -0.098
213   L        -0.600  -0.675  -0.629  -0.602  -0.689  -0.605  -0.675  -0.750  -0.677
214   V        -0.096  -0.073  -0.064  -0.211  -0.168  -0.112  -0.362  -0.325  -0.293
215   Q        -0.372  -0.340  -0.493  -0.102  -0.064  -0.317  -0.362  -0.322  -0.506
216   S        -0.966  -1.036  -1.037  -0.972  -1.084  -1.082  -0.831  -0.901  -0.875
217   I        -1.104  -1.133  -1.068  -1.054  -1.080  -0.964  -0.987  -1.005  -0.906
218   K         1.759   1.779   1.866   1.615   1.645   1.781   1.984   2.012   2.161
219   G        -0.738  -0.713  -0.652  -0.769  -0.735  -0.645  -0.831  -0.801  -0.704
220   S        -0.600  -0.571  -0.580  -0.662  -0.617  -0.648  -0.675  -0.636  -0.623
221   L        -0.190  -0.172  -0.133  -0.526  -0.502  -0.429  -0.468  -0.442  -0.384
222   R        -0.702  -0.716  -0.662  -0.620  -0.640  -0.574  -0.775  -0.788  -0.711
223   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   G         0.004  -0.028  -0.082   0.091   0.043  -0.069  -0.162  -0.211  -0.306
230   H        -1.124  -1.051  -1.050  -1.043  -0.920  -0.950  -0.996  -0.916  -0.888
231   K        -1.104  -1.027  -1.041  -1.131  -1.010  -1.026  -0.987  -0.911  -0.883
232   G        -0.109  -0.150  -0.102  -0.243  -0.335  -0.264  -0.358  -0.416  -0.344
233   A        -0.109  -0.087  -0.083  -0.210  -0.191  -0.175  -0.358  -0.339  -0.319
234   H        -0.536  -0.477  -0.554  -0.355  -0.256  -0.415  -0.571  -0.495  -0.582
235   G        -1.551  -1.524  -1.433  -1.562  -1.509  -1.386  -1.209  -1.180  -1.060
236   R        -1.551  -1.524  -1.433  -1.498  -1.470  -1.322  -1.209  -1.180  -1.060
237   I        -1.470  -1.425  -1.389  -1.409  -1.358  -1.281  -1.144  -1.100  -1.026
238   S        -1.470  -1.425  -1.389  -1.358  -1.283  -1.224  -1.144  -1.100  -1.026
239   K        -0.372  -0.427  -0.526  -0.382  -0.458  -0.625  -0.362  -0.435  -0.547
240   T        -0.966  -0.939  -0.983  -0.742  -0.695  -0.791  -0.831  -0.801  -0.820
241   N        -0.600  -0.623  -0.607  -0.514  -0.541  -0.507  -0.675  -0.695  -0.651
242   G        -1.470  -1.376  -1.394  -1.256  -1.117  -1.144  -1.144  -1.053  -1.030
243   S        -1.104  -1.096  -1.037  -1.145  -1.122  -1.015  -0.987  -0.972  -0.880
244   S        -1.470  -1.480  -1.412  -1.476  -1.505  -1.381  -1.144  -1.145  -1.044
245   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   P        -0.600  -0.557  -0.599  -0.501  -0.458  -0.503  -0.675  -0.636  -0.645
248   R        -0.600  -0.627  -0.602  -0.654  -0.684  -0.623  -0.675  -0.700  -0.649
249   K         1.002   0.922   0.835   0.947   0.847   0.728   1.045   0.906   0.720
250   D        -0.007  -0.036  -0.042  -0.052  -0.093  -0.104  -0.206  -0.240  -0.252
251   P         1.759   1.779   1.866   1.859   1.883   2.024   1.984   2.012   2.161
252   I         1.759   1.779   1.866   1.743   1.772   1.908   1.984   2.012   2.161
253   I         1.759   1.779   1.866   1.743   1.772   1.908   1.984   2.012   2.161
254   L         1.002   1.037   0.859   0.984   1.030   0.787   1.045   1.101   0.765
255   I        -0.234  -0.242  -0.149  -0.497  -0.525  -0.386  -0.518  -0.530  -0.406
256   P         0.498   0.548   0.620   0.214   0.291   0.401   0.107   0.200   0.291
257   S         0.498   0.548   0.620   0.263   0.368   0.461   0.107   0.200   0.291
258   A         0.654   0.594   0.639   0.531   0.403   0.444   0.420   0.293   0.330
259   A         0.288   0.318   0.085   0.416   0.458   0.097   0.263   0.307  -0.052
260   S         0.654   0.678   0.689   0.434   0.474   0.473   0.420   0.459   0.432
261   S         0.654   0.636   0.652   0.438   0.405   0.414   0.420   0.376   0.358
262   I         0.654   0.722   0.702   0.460   0.570   0.518   0.420   0.543   0.458
263   L        -0.007   0.062  -0.004  -0.118  -0.012  -0.106  -0.206  -0.098  -0.195
264   T        -0.007   0.042  -0.029  -0.060   0.023  -0.112  -0.206  -0.127  -0.239
265   V        -0.600  -0.576  -0.602  -0.643  -0.589  -0.612  -0.675  -0.639  -0.646
266   A        -0.600  -0.609  -0.585  -0.654  -0.649  -0.600  -0.675  -0.673  -0.626
267   N         1.759   1.779   1.866   1.796   1.827   1.961   1.984   2.012   2.161
268   I         1.002   0.953   0.845   1.055   0.994   0.831   1.045   0.960   0.738
269   K         1.002   1.046   0.856   0.947   1.008   0.761   1.045   1.115   0.760
270   Q        -0.096  -0.133  -0.083  -0.219  -0.275  -0.205  -0.362  -0.396  -0.319
271   F         1.759   1.779   1.866   1.820   1.849   1.986   1.984   2.012   2.161
272   L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
273   L         1.002   1.089   0.867   1.025   1.139   0.830   1.045   1.185   0.780
274   E        -0.600  -0.580  -0.594  -0.659  -0.621  -0.635  -0.675  -0.649  -0.636
275   S         0.498   0.496   0.590   0.194   0.198   0.344   0.107   0.093   0.229
276   K        -0.966  -1.007  -1.005  -0.938  -1.001  -0.988  -0.831  -0.873  -0.843
277   Y         0.498   0.548   0.620   0.410   0.493   0.599   0.107   0.200   0.291
278   V         0.288   0.363   0.120   0.376   0.480   0.131   0.263   0.372   0.001
279   N        -0.096  -0.133  -0.083  -0.209  -0.249  -0.160  -0.362  -0.396  -0.319
280   P         1.759   1.779   1.866   1.859   1.883   2.024   1.984   2.012   2.161
281   R        -1.470  -1.494  -1.414  -1.352  -1.386  -1.296  -1.144  -1.156  -1.046
282   N        -1.470  -1.479  -1.411  -1.372  -1.405  -1.285  -1.144  -1.145  -1.043
283   L        -0.600  -0.551  -0.582  -0.662  -0.572  -0.629  -0.675  -0.606  -0.622
284   P        -1.124  -1.128  -1.074  -1.020  -1.030  -0.971  -0.996  -0.996  -0.910
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   S        -1.551  -1.524  -1.433  -1.541  -1.474  -1.365  -1.209  -1.179  -1.060
291   V        -1.470  -1.449  -1.413  -1.231  -1.188  -1.161  -1.144  -1.121  -1.045
292   P        -0.966  -0.881  -0.979  -0.674  -0.554  -0.690  -0.831  -0.733  -0.816
293   N        -1.470  -1.477  -1.393  -1.362  -1.357  -1.259  -1.144  -1.143  -1.029
294   G        -0.096  -0.137  -0.071  -0.219  -0.276  -0.169  -0.362  -0.403  -0.307
295   L        -0.372  -0.342  -0.489  -0.274  -0.225  -0.432  -0.362  -0.324  -0.501
296   V        -0.007  -0.055  -0.051  -0.120  -0.197  -0.208  -0.206  -0.272  -0.272
297   N        -0.966  -1.006  -1.001  -0.779  -0.842  -0.838  -0.831  -0.872  -0.839
298   I        -0.738  -0.702  -0.651  -0.912  -0.867  -0.771  -0.831  -0.788  -0.704
299   E        -1.104  -1.101  -1.050  -1.071  -1.067  -0.981  -0.987  -0.976  -0.890
300   K         0.498   0.548   0.620   0.312   0.422   0.512   0.107   0.200   0.291
301   N         0.156   0.205   0.047   0.105   0.178  -0.047   0.068   0.140  -0.109
302   F         0.479   0.502   0.595   0.149   0.174   0.319   0.068   0.106   0.239
303   E        -0.600  -0.661  -0.596  -0.700  -0.792  -0.700  -0.675  -0.730  -0.642
304   R        -0.007  -0.047  -0.057  -0.006  -0.090  -0.114  -0.206  -0.280  -0.280
305   -        -0.162  -0.190  -0.129  -0.365  -0.424  -0.332  -0.411  -0.453  -0.375
306   I         0.288   0.161   0.055   0.398   0.219   0.051   0.263   0.073  -0.098
307   S         0.288   0.161   0.055   0.340   0.178   0.045   0.263   0.073  -0.098
308   R        -0.600  -0.602  -0.621  -0.548  -0.563  -0.595  -0.675  -0.682  -0.670
309   P        -0.966  -1.036  -1.037  -0.750  -0.878  -0.896  -0.831  -0.901  -0.875
310   I        -0.600  -0.675  -0.629  -0.530  -0.619  -0.546  -0.675  -0.750  -0.677
311   R        -0.600  -0.599  -0.592  -0.617  -0.602  -0.607  -0.675  -0.664  -0.637
312   F        -0.007  -0.036  -0.042   0.025  -0.006  -0.014  -0.206  -0.240  -0.252
313   I        -0.600  -0.606  -0.601  -0.530  -0.537  -0.537  -0.675  -0.675  -0.644
314   I         0.498   0.512   0.597   0.222   0.244   0.368   0.107   0.127   0.243
315   V         1.759   1.779   1.866   1.724   1.752   1.890   1.984   2.012   2.161
316   D        -0.007  -0.028  -0.028  -0.083  -0.106  -0.116  -0.206  -0.220  -0.232
317   N         0.288   0.161   0.055   0.434   0.255   0.069   0.263   0.073  -0.098
318   T        -0.372  -0.396  -0.528  -0.188  -0.217  -0.424  -0.362  -0.392  -0.550
319   R        -0.600  -0.517  -0.578  -0.655  -0.526  -0.629  -0.675  -0.564  -0.618
320   M        -0.600  -0.598  -0.603  -0.507  -0.548  -0.545  -0.675  -0.677  -0.650
321   F         1.002   0.953   0.845   1.124   1.059   0.889   1.045   0.960   0.738
322   T         0.927   0.937   0.802   0.992   1.008   0.805   0.919   0.933   0.656
323   K         1.002   1.046   0.856   0.952   1.014   0.769   1.045   1.115   0.760
324   P         1.002   1.016   0.861   1.217   1.236   1.052   1.045   1.066   0.769
325   E         1.002   0.922   0.835   1.035   0.925   0.795   1.045   0.906   0.720
326   Y         1.759   1.779   1.866   1.921   1.949   2.086   1.984   2.012   2.161
327   W         1.759   1.779   1.866   1.962   1.988   2.127   1.984   2.012   2.161
328   D         1.759   1.779   1.866   1.724   1.748   1.890   1.984   2.012   2.161
329   R         1.759   1.779   1.866   1.834   1.860   2.000   1.984   2.012   2.161
330   V         1.759   1.779   1.866   1.724   1.752   1.890   1.984   2.012   2.161
331   V         1.002   1.016   0.861   1.040   1.063   0.845   1.045   1.066   0.769
332   A         1.002   0.922   0.835   1.151   1.054   0.955   1.045   0.906   0.720
333   I         0.498   0.501   0.591   0.225   0.223   0.359   0.107   0.102   0.231
334   F         1.759   1.779   1.866   1.820   1.849   1.986   1.984   2.012   2.161
335   T         1.759   1.779   1.866   1.777   1.806   1.943   1.984   2.012   2.161
336   T         1.759   1.779   1.866   1.777   1.806   1.943   1.984   2.012   2.161
337   G         1.759   1.779   1.866   1.826   1.854   1.992   1.984   2.012   2.161
338   H         0.498   0.548   0.620   0.446   0.533   0.636   0.107   0.200   0.291
339   T        -0.007  -0.078  -0.059  -0.053  -0.164  -0.149  -0.206  -0.303  -0.284
340   W         1.759   1.779   1.866   1.962   1.988   2.127   1.984   2.012   2.161
341   Q         1.759   1.779   1.866   1.863   1.895   2.028   1.984   2.012   2.161
342   F         1.759   1.779   1.866   1.820   1.849   1.986   1.984   2.012   2.161
343   N        -1.470  -1.494  -1.414  -1.373  -1.419  -1.310  -1.144  -1.156  -1.046
344   N        -0.966  -1.036  -1.037  -0.871  -0.995  -1.032  -0.831  -0.901  -0.875
345   Y         1.759   1.779   1.866   1.921   1.949   2.086   1.984   2.012   2.161
346   Q        -0.600  -0.640  -0.617  -0.592  -0.664  -0.640  -0.675  -0.717  -0.666
347   W         0.288   0.318   0.085   0.671   0.711   0.397   0.263   0.307  -0.052
348   N        -0.007   0.066   0.007  -0.141  -0.020  -0.098  -0.206  -0.087  -0.178
349   S        -1.470  -1.405  -1.386  -1.477  -1.368  -1.362  -1.144  -1.080  -1.024
350   P         1.759   1.779   1.866   1.859   1.883   2.024   1.984   2.012   2.161
351   Q        -1.104  -1.133  -1.068  -0.949  -0.981  -0.874  -0.987  -1.005  -0.906
352   E        -0.600  -0.602  -0.621  -0.553  -0.555  -0.555  -0.675  -0.682  -0.670
353   L         1.759   1.779   1.866   1.668   1.693   1.834   1.984   2.012   2.161
354   F         1.759   1.779   1.866   1.820   1.849   1.986   1.984   2.012   2.161
355   Q         1.002   0.922   0.835   1.208   1.113   0.994   1.045   0.906   0.720
356   R        -0.096  -0.083  -0.062  -0.094  -0.075  -0.044  -0.362  -0.342  -0.296
357   C        -0.234  -0.242  -0.149  -0.154  -0.194  -0.058  -0.518  -0.530  -0.406
358   K         0.288   0.318   0.085   0.289   0.332   0.009   0.263   0.307  -0.052
359   G         1.759   1.779   1.866   1.826   1.854   1.992   1.984   2.012   2.161
360   Y         0.498   0.526   0.606   0.410   0.454   0.575   0.107   0.154   0.261
361   Y         0.288   0.161   0.055   0.603   0.425   0.265   0.263   0.073  -0.098
362   F        -0.007  -0.070  -0.058  -0.040  -0.150  -0.153  -0.206  -0.297  -0.283
363   H        -0.966  -1.036  -1.037  -0.682  -0.796  -0.833  -0.831  -0.901  -0.875
364   F         0.498   0.548   0.620   0.430   0.526   0.624   0.107   0.200   0.291
365   A        -1.836  -1.810  -1.716  -1.575  -1.536  -1.399  -1.300  -1.273  -1.152
366   G         1.002   0.953   0.845   1.151   1.090   0.934   1.045   0.960   0.738
367   D         1.002   1.016   0.861   1.036   1.055   0.839   1.045   1.066   0.769
368   S        -1.104  -1.061  -1.052  -1.143  -1.046  -1.058  -0.987  -0.937  -0.892
369   V        -0.372  -0.419  -0.537  -0.232  -0.298  -0.472  -0.362  -0.422  -0.561
370   P         1.002   0.922   0.835   1.204   1.101   0.990   1.045   0.906   0.720
371   Q        -0.600  -0.517  -0.578  -0.496  -0.361  -0.464  -0.675  -0.564  -0.618
372   H        -1.104  -1.118  -1.066  -0.882  -0.901  -0.805  -0.987  -0.993  -0.904
373   V        -0.600  -0.623  -0.607  -0.643  -0.673  -0.639  -0.675  -0.695  -0.651
374   Q        -1.104  -1.133  -1.068  -1.046  -1.076  -0.971  -0.987  -1.005  -0.906
375   Q        -0.096  -0.114  -0.079  -0.174  -0.196  -0.134  -0.362  -0.373  -0.315
376   W         1.759   1.779   1.866   1.962   1.988   2.127   1.984   2.012   2.161
377   N         1.759   1.779   1.866   1.796   1.827   1.961   1.984   2.012   2.161
378   V         1.759   1.779   1.866   1.724   1.752   1.890   1.984   2.012   2.161
379   E        -0.600  -0.521  -0.580  -0.618  -0.508  -0.571  -0.675  -0.583  -0.620
380   K        -0.600  -0.675  -0.629  -0.751  -0.848  -0.771  -0.675  -0.750  -0.677
381   V        -0.007  -0.047  -0.044  -0.138  -0.189  -0.210  -0.206  -0.252  -0.260
382   E        -0.600  -0.643  -0.620  -0.628  -0.686  -0.652  -0.675  -0.721  -0.669
383   L        -0.234  -0.246  -0.156  -0.517  -0.540  -0.400  -0.518  -0.536  -0.415
384   D         1.002   0.922   0.835   1.036   0.926   0.797   1.045   0.906   0.720
385   K         0.498   0.502   0.593   0.190   0.199   0.342   0.107   0.106   0.234
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   N        -0.738  -0.756  -0.657  -0.848  -0.876  -0.725  -0.831  -0.838  -0.709
388   K         0.288   0.161   0.055   0.304   0.137  -0.010   0.263   0.073  -0.098
389   R         1.759   1.779   1.866   1.834   1.860   2.000   1.984   2.012   2.161
390   F         1.002   0.922   0.835   1.166   1.068   0.954   1.045   0.906   0.720
391   K         0.288   0.234   0.077   0.287   0.212  -0.007   0.263   0.179  -0.064
392   D         1.759   1.779   1.866   1.724   1.748   1.890   1.984   2.012   2.161
393   V        -0.738  -0.700  -0.658  -0.901  -0.828  -0.762  -0.831  -0.785  -0.710
394   E         0.288   0.318   0.085   0.415   0.454   0.143   0.263   0.307  -0.052
395   V         0.654   0.636   0.652   0.514   0.478   0.478   0.420   0.376   0.358
396   V         1.002   1.046   0.856   1.021   1.083   0.802   1.045   1.115   0.760
397   R         0.288   0.161   0.055   0.465   0.274   0.091   0.263   0.073  -0.098
398   Y        -1.104  -1.133  -1.068  -0.907  -0.948  -0.836  -0.987  -1.005  -0.906
399   F         1.002   0.922   0.835   1.124   1.014   0.873   1.045   0.906   0.720
400   W         1.759   1.779   1.866   1.962   1.988   2.127   1.984   2.012   2.161
401   H        -1.836  -1.810  -1.716  -1.596  -1.581  -1.419  -1.300  -1.273  -1.152
402   S        -1.470  -1.448  -1.394  -1.542  -1.521  -1.431  -1.144  -1.118  -1.030
403   L         0.498   0.501   0.591   0.191   0.183   0.319   0.107   0.103   0.231
404   E         1.002   0.953   0.845   1.035   0.968   0.811   1.045   0.960   0.738
405   K         0.498   0.498   0.590   0.190   0.195   0.343   0.107   0.097   0.229
406   E        -0.966  -1.036  -1.037  -0.801  -0.893  -0.896  -0.831  -0.901  -0.875
407   L         0.654   0.594   0.639   0.561   0.469   0.546   0.420   0.293   0.330
408   I        -0.966  -0.953  -0.980  -0.822  -0.820  -0.848  -0.831  -0.816  -0.817
409   S        -0.096  -0.029  -0.062  -0.218  -0.119  -0.161  -0.362  -0.279  -0.295
410   R         0.654   0.678   0.689   0.572   0.610   0.590   0.420   0.459   0.432
411   G         1.002   0.922   0.835   1.178   1.080   0.972   1.045   0.906   0.720
412   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
413   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
414   Y        -0.007   0.005  -0.051   0.189   0.184   0.125  -0.206  -0.218  -0.271
415   -        -0.162  -0.190  -0.129  -0.159  -0.206  -0.120  -0.411  -0.453  -0.375
416   -         0.479   0.500   0.594   0.157   0.208   0.348   0.068   0.102   0.238
417   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
418   R        -0.966  -0.966  -1.001  -0.678  -0.690  -0.731  -0.831  -0.827  -0.839
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06697
Output conservation file - output/Q06697
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
