1     M         1.909   1.944   2.018   2.189   2.241   2.359   2.125   2.180   2.304
2     D        -0.142  -0.068  -0.092  -0.277  -0.147  -0.211  -0.353  -0.244  -0.285
3     F        -0.142  -0.068  -0.092  -0.123  -0.015  -0.046  -0.353  -0.244  -0.285
4     K        -0.825  -0.810  -0.750  -0.823  -0.798  -0.705  -0.849  -0.824  -0.742
5     A        -0.142  -0.145  -0.105  -0.140  -0.143  -0.091  -0.353  -0.358  -0.303
6     S        -0.825  -0.810  -0.750  -0.862  -0.827  -0.745  -0.849  -0.824  -0.742
7     G         0.800   0.752   0.783   0.899   0.803   0.836   0.638   0.540   0.569
8     T        -0.142  -0.151  -0.105  -0.162  -0.175  -0.107  -0.353  -0.366  -0.303
9     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    K         1.909   1.944   2.018   1.761   1.810   1.924   2.125   2.180   2.304
14    T        -0.825  -0.810  -0.750  -1.111  -1.076  -0.998  -0.849  -0.824  -0.742
15    G         1.909   1.944   2.018   2.100   2.155   2.269   2.125   2.180   2.304
16    K        -0.142  -0.163  -0.120  -0.293  -0.320  -0.253  -0.353  -0.383  -0.325
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    K        -0.142  -0.100  -0.094  -0.210  -0.139  -0.144  -0.353  -0.290  -0.288
25    V        -0.825  -0.810  -0.750  -0.937  -0.906  -0.821  -0.849  -0.824  -0.742
26    V        -0.142  -0.100  -0.094  -0.288  -0.216  -0.233  -0.353  -0.290  -0.288
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    P        -1.265  -1.246  -1.195  -1.154  -1.143  -1.042  -1.047  -1.019  -0.945
36    A        -1.265  -1.246  -1.195  -0.945  -0.899  -0.829  -1.047  -1.019  -0.945
37    K        -0.719  -0.665  -0.678  -0.744  -0.654  -0.686  -0.730  -0.659  -0.663
38    A        -1.265  -1.246  -1.195  -1.163  -1.115  -1.051  -1.047  -1.019  -0.945
39    F         0.582   0.634   0.666   0.169   0.241   0.292   0.222   0.312   0.339
40    E        -1.265  -1.246  -1.195  -1.236  -1.187  -1.125  -1.047  -1.019  -0.945
41    E        -0.719  -0.738  -0.700  -0.844  -0.860  -0.836  -0.730  -0.747  -0.688
42    I        -0.719  -0.628  -0.676  -0.762  -0.638  -0.688  -0.730  -0.615  -0.661
43    V        -0.172  -0.126  -0.120  -0.463  -0.418  -0.387  -0.413  -0.350  -0.333
44    Q         0.035   0.077  -0.013   0.052   0.116  -0.034  -0.096  -0.032  -0.169
45    T        -1.625  -1.603  -1.559  -1.611  -1.556  -1.506  -1.179  -1.150  -1.080
46    N        -0.542  -0.595  -0.630  -0.333  -0.439  -0.488  -0.519  -0.582  -0.606
47    R         0.198   0.284   0.064   0.475   0.600   0.280   0.142   0.270  -0.055
48    D        -1.169  -1.102  -1.131  -1.082  -0.975  -1.021  -0.959  -0.881  -0.887
49    V        -0.714  -0.749  -0.697  -0.709  -0.778  -0.680  -0.739  -0.766  -0.689
50    L        -0.086  -0.093  -0.093  -0.246  -0.291  -0.262  -0.298  -0.314  -0.300
51    K        -0.542  -0.607  -0.633  -0.333  -0.446  -0.503  -0.519  -0.596  -0.610
52    K        -1.169  -1.176  -1.147  -1.067  -1.060  -1.010  -0.959  -0.959  -0.902
53    S         1.909   1.944   2.018   1.786   1.839   1.950   2.125   2.180   2.304
54    A        -1.169  -1.087  -1.130  -1.111  -0.965  -1.049  -0.959  -0.866  -0.886
55    F         0.654   0.621   0.660   0.281   0.216   0.280   0.363   0.288   0.326
56    L         0.542   0.570   0.637   0.127   0.144   0.255   0.142   0.185   0.280
57    S        -0.714  -0.658  -0.681  -0.717  -0.663  -0.668  -0.739  -0.671  -0.673
58    D        -0.714  -0.668  -0.681  -0.901  -0.833  -0.857  -0.739  -0.682  -0.673
59    L        -0.714  -0.730  -0.690  -0.877  -0.889  -0.823  -0.739  -0.749  -0.682
60    L        -1.169  -1.168  -1.145  -1.093  -1.063  -1.057  -0.959  -0.951  -0.900
61    E        -1.169  -1.175  -1.153  -1.184  -1.212  -1.203  -0.959  -0.957  -0.908
62    N        -1.169  -1.183  -1.153  -1.004  -1.009  -0.948  -0.959  -0.964  -0.908
63    L         1.909   1.944   2.018   1.647   1.695   1.808   2.125   2.180   2.304
64    Q        -0.542  -0.567  -0.601  -0.342  -0.407  -0.457  -0.519  -0.550  -0.572
65    P        -1.169  -1.165  -1.152  -0.978  -0.981  -0.959  -0.959  -0.948  -0.906
66    H        -1.169  -1.087  -1.130  -0.873  -0.756  -0.798  -0.959  -0.866  -0.886
67    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    N        -1.169  -1.176  -1.147  -1.112  -1.152  -1.088  -0.959  -0.959  -0.902
70    I         0.198   0.105   0.037   0.310   0.171   0.067   0.142   0.003  -0.095
71    K        -0.714  -0.747  -0.687  -0.811  -0.837  -0.759  -0.739  -0.764  -0.678
72    K        -0.714  -0.730  -0.684  -0.681  -0.703  -0.624  -0.739  -0.748  -0.676
73    I         0.198   0.105   0.037   0.365   0.247   0.149   0.142   0.003  -0.095
74    R         1.020   0.890   0.876   1.207   1.007   0.973   1.024   0.793   0.746
75    C         1.909   1.944   2.018   2.175   2.224   2.345   2.125   2.180   2.304
76    V         0.198   0.107   0.029   0.055  -0.083  -0.188   0.142   0.006  -0.107
77    A         1.020   0.890   0.876   1.180   1.000   0.965   1.024   0.793   0.746
78    I         1.020   1.075   0.893   0.826   0.901   0.642   1.024   1.111   0.777
79    G         1.909   1.944   2.018   2.089   2.145   2.258   2.125   2.180   2.304
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    N        -0.086  -0.158  -0.094  -0.215  -0.293  -0.200  -0.298  -0.380  -0.297
82    F        -0.086  -0.152  -0.088  -0.040  -0.131  -0.023  -0.298  -0.372  -0.287
83    K        -1.169  -1.176  -1.162  -1.119  -1.125  -1.087  -0.959  -0.958  -0.916
84    E        -0.542  -0.609  -0.629  -0.358  -0.438  -0.466  -0.519  -0.598  -0.605
85    D        -0.714  -0.738  -0.700  -0.836  -0.859  -0.801  -0.739  -0.756  -0.692
86    F        -0.542  -0.579  -0.624  -0.532  -0.638  -0.708  -0.519  -0.564  -0.599
87    P        -0.542  -0.579  -0.624  -0.283  -0.354  -0.412  -0.519  -0.564  -0.599
88    A         1.909   1.944   2.018   2.002   2.062   2.169   2.125   2.180   2.304
89    T        -1.169  -1.183  -1.153  -1.163  -1.214  -1.180  -0.959  -0.964  -0.908
90    Y        -0.086  -0.147  -0.075  -0.128  -0.245  -0.132  -0.298  -0.364  -0.271
91    Q         1.909   1.944   2.018   2.060   2.113   2.228   2.125   2.180   2.304
92    F         1.020   1.075   0.893   0.833   0.905   0.654   1.024   1.111   0.777
93    A         1.020   0.890   0.876   1.156   0.965   0.924   1.024   0.793   0.746
94    L         1.020   1.053   0.890   0.833   0.877   0.649   1.024   1.075   0.771
95    L         1.020   0.890   0.876   0.833   0.645   0.627   1.024   0.793   0.746
96    L        -0.542  -0.579  -0.624  -0.676  -0.737  -0.786  -0.519  -0.564  -0.599
97    E         1.020   1.053   0.890   1.101   1.155   0.930   1.024   1.075   0.771
98    I        -0.086  -0.093  -0.093  -0.384  -0.389  -0.369  -0.298  -0.314  -0.300
99    T        -1.169  -1.175  -1.153  -0.995  -0.970  -0.914  -0.959  -0.957  -0.908
100   D        -1.169  -1.176  -1.147  -0.982  -1.024  -0.935  -0.959  -0.959  -0.902
101   Y        -1.169  -1.183  -1.153  -1.242  -1.252  -1.189  -0.959  -0.964  -0.908
102   I        -0.258  -0.231  -0.173  -0.592  -0.536  -0.457  -0.519  -0.479  -0.401
103   K        -0.258  -0.237  -0.171  -0.522  -0.485  -0.389  -0.519  -0.487  -0.398
104   S        -1.169  -1.156  -1.139  -1.126  -1.151  -1.093  -0.959  -0.940  -0.894
105   E        -0.719  -0.731  -0.702  -0.678  -0.677  -0.645  -0.730  -0.740  -0.690
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   D        -0.719  -0.715  -0.686  -0.842  -0.816  -0.792  -0.730  -0.722  -0.672
108   E        -0.719  -0.740  -0.696  -0.664  -0.702  -0.623  -0.730  -0.749  -0.683
109   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   V         0.654   0.621   0.664   0.700   0.644   0.716   0.363   0.286   0.335
114   S         1.909   1.944   2.018   1.786   1.839   1.950   2.125   2.180   2.304
115   L         0.654   0.621   0.664   0.281   0.215   0.286   0.363   0.286   0.335
116   Y         1.909   1.944   2.018   2.035   2.091   2.203   2.125   2.180   2.304
117   D         1.909   1.944   2.018   1.899   1.953   2.064   2.125   2.180   2.304
118   P         1.909   1.944   2.018   2.039   2.084   2.206   2.125   2.180   2.304
119   I        -0.086  -0.147  -0.081  -0.090  -0.159  -0.074  -0.298  -0.363  -0.279
120   F         1.909   1.944   2.018   1.944   1.988   2.110   2.125   2.180   2.304
121   T        -0.542  -0.595  -0.630  -0.490  -0.617  -0.664  -0.519  -0.582  -0.606
122   K        -0.086  -0.081  -0.091  -0.279  -0.297  -0.306  -0.298  -0.300  -0.297
123   E        -1.169  -1.165  -1.152  -1.242  -1.233  -1.233  -0.959  -0.948  -0.906
124   E         1.020   1.075   0.893   1.074   1.156   0.886   1.024   1.111   0.777
125   I        -1.169  -1.176  -1.162  -1.192  -1.189  -1.209  -0.959  -0.958  -0.916
126   Q        -0.714  -0.666  -0.675  -0.712  -0.635  -0.657  -0.739  -0.682  -0.666
127   Y        -0.086  -0.004  -0.066  -0.083   0.033  -0.046  -0.298  -0.187  -0.258
128   L         0.654   0.711   0.701   0.265   0.356   0.324   0.363   0.463   0.408
129   K        -0.542  -0.609  -0.629  -0.564  -0.675  -0.693  -0.519  -0.598  -0.605
130   S        -1.169  -1.077  -1.130  -1.049  -0.893  -0.988  -0.959  -0.856  -0.886
131   L        -1.265  -1.246  -1.195  -1.322  -1.312  -1.213  -1.047  -1.019  -0.945
132   G         0.035   0.088  -0.001   0.185   0.278   0.108  -0.096  -0.016  -0.151
133   S        -0.172  -0.209  -0.128  -0.376  -0.426  -0.304  -0.413  -0.452  -0.343
134   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   W        -0.086  -0.152  -0.088   0.154   0.079   0.173  -0.298  -0.372  -0.287
136   L        -1.625  -1.603  -1.559  -1.593  -1.545  -1.488  -1.179  -1.150  -1.080
137   I         0.198   0.105   0.037   0.250   0.084  -0.024   0.142   0.003  -0.095
138   E        -1.169  -1.184  -1.153  -1.073  -1.082  -1.044  -0.959  -0.965  -0.908
139   E         0.198   0.143   0.057   0.239   0.156   0.005   0.142   0.054  -0.065
140   E        -1.169  -1.184  -1.153  -1.094  -1.107  -1.068  -0.959  -0.965  -0.908
141   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   D         0.198   0.143   0.057   0.323   0.241   0.124   0.142   0.054  -0.065
146   A         0.198   0.262   0.061   0.371   0.468   0.177   0.142   0.239  -0.059
147   I        -1.265  -1.242  -1.195  -1.119  -1.072  -1.006  -1.047  -1.016  -0.945
148   D        -0.714  -0.757  -0.696  -0.748  -0.825  -0.717  -0.739  -0.773  -0.688
149   Y        -1.169  -1.102  -1.131  -0.765  -0.646  -0.704  -0.959  -0.881  -0.887
150   E        -0.714  -0.658  -0.681  -0.965  -0.903  -0.899  -0.739  -0.671  -0.673
151   S        -0.542  -0.456  -0.604  -0.577  -0.448  -0.672  -0.519  -0.405  -0.575
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   V         0.198   0.262   0.061   0.349   0.447   0.145   0.142   0.239  -0.059
154   L         1.020   1.072   0.902   0.886   0.953   0.754   1.024   1.106   0.794
155   Y        -0.086  -0.152  -0.092  -0.128  -0.255  -0.166  -0.298  -0.371  -0.294
156   F         0.654   0.629   0.664   0.597   0.543   0.595   0.363   0.303   0.334
157   L         0.654   0.629   0.664   0.403   0.371   0.444   0.363   0.303   0.334
158   P         1.909   1.944   2.018   2.039   2.084   2.206   2.125   2.180   2.304
159   H         1.909   1.944   2.018   2.121   2.176   2.290   2.125   2.180   2.304
160   A         1.020   0.890   0.876   1.232   1.071   1.055   1.024   0.793   0.746
161   P         0.654   0.711   0.711   0.572   0.668   0.638   0.363   0.462   0.428
162   L         1.020   0.890   0.876   0.834   0.649   0.629   1.024   0.793   0.746
163   D        -0.086  -0.152  -0.088  -0.236  -0.338  -0.250  -0.298  -0.372  -0.287
164   L         1.909   1.944   2.018   1.647   1.695   1.808   2.125   2.180   2.304
165   T         1.020   0.890   0.876   1.150   0.975   0.954   1.024   0.793   0.746
166   E         1.909   1.944   2.018   1.892   1.950   2.057   2.125   2.180   2.304
167   N        -1.169  -1.194  -1.152  -1.069  -1.099  -1.038  -0.959  -0.974  -0.907
168   I         0.198   0.107   0.029   0.442   0.330   0.211   0.142   0.006  -0.107
169   L         0.654   0.711   0.701   0.265   0.356   0.324   0.363   0.463   0.408
170   S        -0.714  -0.660  -0.685  -0.750  -0.652  -0.714  -0.739  -0.674  -0.676
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   S        -1.625  -1.603  -1.559  -1.463  -1.421  -1.356  -1.179  -1.150  -1.080
175   Q        -1.169  -1.175  -1.153  -1.082  -1.096  -1.054  -0.959  -0.957  -0.908
176   R        -1.169  -1.168  -1.145  -1.132  -1.141  -1.080  -0.959  -0.951  -0.900
177   P         1.909   1.944   2.018   2.039   2.084   2.206   2.125   2.180   2.304
178   H        -0.542  -0.607  -0.633  -0.503  -0.594  -0.619  -0.519  -0.596  -0.610
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   L        -1.169  -1.176  -1.147  -1.203  -1.214  -1.141  -0.959  -0.959  -0.902
182   W        -1.169  -1.165  -1.152  -0.831  -0.803  -0.821  -0.959  -0.948  -0.906
183   L         1.020   0.890   0.876   0.883   0.717   0.713   1.024   0.793   0.746
184   A         0.654   0.629   0.664   0.674   0.635   0.677   0.363   0.303   0.334
185   N         1.909   1.944   2.018   1.944   1.996   2.110   2.125   2.180   2.304
186   N        -0.714  -0.662  -0.683  -0.665  -0.585  -0.597  -0.739  -0.676  -0.674
187   M        -0.714  -0.661  -0.679  -0.700  -0.666  -0.651  -0.739  -0.675  -0.670
188   I        -0.542  -0.579  -0.627  -0.521  -0.563  -0.687  -0.519  -0.564  -0.603
189   S        -0.714  -0.730  -0.687  -0.784  -0.851  -0.755  -0.739  -0.748  -0.679
190   H         1.020   0.890   0.876   1.322   1.144   1.122   1.024   0.793   0.746
191   T         1.020   0.890   0.876   1.141   0.961   0.938   1.024   0.793   0.746
192   D         1.909   1.944   2.018   1.899   1.953   2.064   2.125   2.180   2.304
193   R         1.020   0.890   0.876   1.240   1.055   1.029   1.024   0.793   0.746
194   Y        -0.086  -0.151  -0.093  -0.372  -0.481  -0.376  -0.298  -0.370  -0.297
195   T         1.020   0.890   0.876   1.151   0.973   0.955   1.024   0.793   0.746
196   K         0.198   0.128   0.033   0.121  -0.004  -0.151   0.142   0.034  -0.101
197   A         0.198   0.262   0.061   0.200   0.290   0.013   0.142   0.239  -0.059
198   K        -0.086  -0.152  -0.092  -0.217  -0.314  -0.213  -0.298  -0.371  -0.294
199   L         0.654   0.615   0.658   0.265   0.195   0.255   0.363   0.276   0.322
200   C        -1.169  -1.175  -1.153  -0.747  -0.759  -0.700  -0.959  -0.957  -0.908
201   E         0.198   0.107   0.029   0.249   0.098  -0.035   0.142   0.006  -0.107
202   N        -0.258  -0.231  -0.173  -0.492  -0.443  -0.359  -0.519  -0.479  -0.400
203   Y         1.909   1.944   2.018   2.035   2.091   2.203   2.125   2.180   2.304
204   P         1.020   1.053   0.890   1.245   1.288   1.072   1.024   1.075   0.771
205   N        -0.258  -0.234  -0.170  -0.568  -0.519  -0.432  -0.519  -0.483  -0.397
206   L         0.198   0.090   0.020   0.055  -0.100  -0.202   0.142  -0.018  -0.120
207   S         0.198   0.105   0.037   0.271   0.143   0.075   0.142   0.003  -0.095
208   K         0.198   0.284   0.064   0.091   0.215  -0.141   0.142   0.270  -0.055
209   L         0.198   0.143   0.057   0.109   0.047  -0.067   0.142   0.054  -0.065
210   V         0.198   0.090   0.020   0.434   0.291   0.185   0.142  -0.018  -0.120
211   H        -0.719  -0.712  -0.702  -0.544  -0.536  -0.537  -0.730  -0.715  -0.690
212   Y        -0.719  -0.704  -0.700  -0.643  -0.611  -0.629  -0.730  -0.704  -0.688
213   L         0.035   0.064  -0.043  -0.266  -0.222  -0.406  -0.096  -0.049  -0.212
214   Q        -1.265  -1.260  -1.195  -1.121  -1.110  -1.008  -1.047  -1.031  -0.945
215   T        -0.719  -0.702  -0.694  -0.734  -0.705  -0.710  -0.730  -0.703  -0.680
216   N         0.035   0.042  -0.049   0.144   0.157   0.010  -0.096  -0.083  -0.222
217   A        -0.719  -0.708  -0.712  -0.841  -0.825  -0.828  -0.730  -0.709  -0.702
218   P        -1.265  -1.260  -1.195  -1.159  -1.148  -1.047  -1.047  -1.031  -0.945
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   K        -0.825  -0.813  -0.750  -0.989  -0.963  -0.874  -0.849  -0.827  -0.742
227   A        -0.142  -0.143  -0.120  -0.179  -0.177  -0.163  -0.353  -0.355  -0.325
228   H        -0.825  -0.813  -0.750  -0.815  -0.811  -0.697  -0.849  -0.827  -0.742
229   D         0.542   0.565   0.634   0.265   0.299   0.402   0.142   0.174   0.274
230   V        -0.825  -0.813  -0.750  -0.820  -0.814  -0.702  -0.849  -0.827  -0.742
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   D         1.909   1.944   2.018   1.886   1.938   2.051   2.125   2.180   2.304
234   G         0.922   0.924   0.814   1.114   1.121   0.927   0.856   0.854   0.628
235   F         1.909   1.944   2.018   1.961   2.014   2.128   2.125   2.180   2.304
236   A        -1.265  -1.260  -1.195  -1.067  -1.056  -0.953  -1.047  -1.031  -0.945
237   T        -0.172  -0.168  -0.131  -0.221  -0.218  -0.168  -0.413  -0.402  -0.347
238   F        -0.172  -0.151  -0.135  -0.166  -0.136  -0.096  -0.413  -0.383  -0.352
239   I        -0.719  -0.699  -0.686  -0.768  -0.733  -0.732  -0.730  -0.699  -0.672
240   P        -0.719  -0.716  -0.702  -0.816  -0.817  -0.788  -0.730  -0.719  -0.690
241   K         0.922   0.952   0.828   0.794   0.837   0.625   0.856   0.904   0.655
242   R         0.582   0.600   0.645   0.428   0.451   0.491   0.222   0.246   0.295
243   K         0.800   0.852   0.783   0.570   0.649   0.512   0.638   0.725   0.569
244   R         0.800   0.768   0.764   0.859   0.794   0.756   0.638   0.571   0.531
245   K        -0.142  -0.143  -0.120  -0.299  -0.308  -0.260  -0.353  -0.355  -0.325
246   N        -0.719  -0.717  -0.694  -0.633  -0.629  -0.610  -0.730  -0.723  -0.680
247   R         0.035   0.077  -0.013  -0.041   0.017  -0.107  -0.096  -0.032  -0.169
248   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   S        -1.265  -1.246  -1.195  -1.296  -1.258  -1.186  -1.047  -1.019  -0.945
252   K         0.582   0.583   0.647   0.330   0.330   0.432   0.222   0.212   0.299
253   L        -0.719  -0.657  -0.674  -0.757  -0.687  -0.670  -0.730  -0.650  -0.658
254   K        -0.719  -0.738  -0.700  -0.849  -0.918  -0.817  -0.730  -0.747  -0.688
255   V         0.198   0.287   0.064   0.346   0.469   0.146   0.142   0.274  -0.055
256   T         0.035   0.049  -0.045  -0.074  -0.054  -0.209  -0.096  -0.072  -0.216
257   P         0.582   0.603   0.647   0.430   0.460   0.528   0.222   0.251   0.300
258   S        -0.172  -0.164  -0.136  -0.221  -0.209  -0.179  -0.413  -0.398  -0.353
259   D         0.035   0.022  -0.049   0.106   0.085  -0.055  -0.096  -0.112  -0.222
260   I         1.909   1.944   2.018   1.890   1.943   2.055   2.125   2.180   2.304
261   D        -0.172  -0.145  -0.123  -0.344  -0.307  -0.265  -0.413  -0.376  -0.337
262   Y         1.909   1.944   2.018   2.027   2.082   2.195   2.125   2.180   2.304
263   D         0.922   0.959   0.825   0.898   0.954   0.721   0.856   0.915   0.648
264   S        -0.719  -0.707  -0.696  -0.751  -0.729  -0.706  -0.730  -0.708  -0.683
265   I        -0.719  -0.704  -0.700  -0.697  -0.671  -0.667  -0.730  -0.704  -0.688
266   A        -1.265  -1.260  -1.195  -1.173  -1.159  -1.061  -1.047  -1.031  -0.945
267   P        -0.719  -0.716  -0.702  -0.612  -0.600  -0.556  -0.730  -0.719  -0.690
268   K         0.922   0.933   0.821   1.034   1.052   0.847   0.856   0.870   0.642
269   F         1.909   1.944   2.018   1.961   2.014   2.128   2.125   2.180   2.304
270   K        -0.719  -0.689  -0.686  -0.800  -0.757  -0.746  -0.730  -0.687  -0.672
271   S        -0.719  -0.716  -0.702  -0.839  -0.835  -0.832  -0.730  -0.719  -0.690
272   C        -0.719  -0.704  -0.700  -0.381  -0.353  -0.358  -0.730  -0.704  -0.688
273   Q        -0.719  -0.712  -0.702  -0.776  -0.765  -0.797  -0.730  -0.715  -0.690
274   I         0.922   0.924   0.814   0.862   0.862   0.641   0.856   0.854   0.628
275   L        -1.265  -1.260  -1.195  -1.256  -1.249  -1.146  -1.047  -1.031  -0.945
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   T        -0.825  -0.800  -0.750  -0.814  -0.767  -0.695  -0.849  -0.813  -0.742
287   D         0.800   0.715   0.764   0.747   0.602   0.664   0.638   0.471   0.531
288   F         0.800   0.871   0.796   0.843   0.943   0.836   0.638   0.759   0.594
289   D        -0.142  -0.163  -0.122  -0.226  -0.258  -0.204  -0.353  -0.385  -0.328
290   E         0.800   0.868   0.786   0.783   0.892   0.739   0.638   0.754   0.574
291   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   K        -0.719  -0.708  -0.712  -0.692  -0.675  -0.718  -0.730  -0.709  -0.702
293   Y        -0.719  -0.712  -0.702  -0.723  -0.713  -0.726  -0.730  -0.715  -0.690
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   L        -0.172  -0.151  -0.135  -0.527  -0.500  -0.487  -0.413  -0.383  -0.352
299   K        -0.719  -0.712  -0.702  -0.703  -0.693  -0.656  -0.730  -0.715  -0.690
300   E        -0.172  -0.164  -0.128  -0.177  -0.162  -0.112  -0.413  -0.397  -0.344
301   K        -0.719  -0.704  -0.700  -0.793  -0.766  -0.756  -0.730  -0.704  -0.688
302   P        -1.265  -1.260  -1.195  -1.015  -1.001  -0.901  -1.047  -1.031  -0.945
303   W         1.909   1.944   2.018   2.204   2.260   2.374   2.125   2.180   2.304
304   I        -1.169  -1.176  -1.162  -1.001  -1.008  -1.018  -0.959  -0.958  -0.916
305   N        -1.169  -1.165  -1.152  -0.961  -0.950  -0.924  -0.959  -0.948  -0.906
306   S         1.020   0.890   0.876   0.984   0.808   0.786   1.024   0.793   0.746
307   F         1.909   1.944   2.018   1.944   1.988   2.110   2.125   2.180   2.304
308   S         0.198   0.143   0.057   0.190   0.104  -0.016   0.142   0.054  -0.065
309   D         1.909   1.944   2.018   1.899   1.953   2.064   2.125   2.180   2.304
310   L         1.020   1.053   0.890   0.826   0.873   0.637   1.024   1.075   0.771
311   T        -0.086  -0.076  -0.092  -0.161  -0.167  -0.189  -0.298  -0.293  -0.298
312   L        -0.086  -0.054  -0.089  -0.349  -0.317  -0.323  -0.298  -0.271  -0.293
313   H         1.020   1.100   0.904   1.304   1.417   1.138   1.024   1.152   0.797
314   A        -1.625  -1.603  -1.559  -1.248  -1.217  -1.138  -1.179  -1.150  -1.080
315   I         1.020   0.890   0.876   1.131   0.968   0.948   1.024   0.793   0.746
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   Y        -0.542  -0.469  -0.591  -0.502  -0.392  -0.563  -0.519  -0.422  -0.560
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06688
Output conservation file - output/Q06688
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
