1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    M         0.957   1.007   1.062   1.115   1.174   1.247   1.012   1.077   1.157
32    S         0.189   0.045  -0.102   0.318   0.127  -0.122   0.178  -0.039  -0.311
33    R        -0.189  -0.329  -0.196  -0.031  -0.324  -0.144  -0.418  -0.670  -0.477
34    V        -0.543  -0.641  -0.854  -0.298  -0.444  -0.722  -0.537  -0.668  -0.924
35    G         0.189   0.045  -0.102   0.391   0.199  -0.074   0.178  -0.039  -0.311
36    V        -1.231  -1.202  -1.397  -1.099  -1.066  -1.478  -1.133  -1.083  -1.241
37    M        -0.878  -1.024  -0.904  -1.232  -1.395  -1.100  -1.014  -1.167  -0.992
38    V         0.189   0.404  -0.079   0.322   0.585  -0.086   0.178   0.476  -0.271
39    L        -0.543  -0.874  -0.882  -0.735  -1.133  -1.024  -0.537  -0.956  -0.960
40    G         0.957   1.007   1.062   1.071   1.143   1.210   1.012   1.077   1.157
41    P         0.189   0.045  -0.102   0.344   0.160  -0.102   0.178  -0.039  -0.311
42    A         0.957   1.007   1.062   0.972   1.046   1.127   1.012   1.077   1.157
43    G         0.189   0.045  -0.102   0.394   0.203  -0.066   0.178  -0.039  -0.311
44    A        -1.029  -1.049  -0.902  -1.158  -1.156  -0.922  -1.253  -1.202  -0.989
45    G         0.957   1.007   1.062   1.071   1.143   1.210   1.012   1.077   1.157
46    K         0.957   1.007   1.062   1.055   1.126   1.196   1.012   1.077   1.157
47    S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
48    T         0.957   1.007   1.062   1.105   1.162   1.239   1.012   1.077   1.157
49    F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
50    C         0.957   1.007   1.062   1.224   1.287   1.339   1.012   1.077   1.157
51    N        -0.543  -0.874  -0.882  -0.327  -0.786  -0.844  -0.537  -0.956  -0.960
52    S        -0.392  -0.338  -0.197  -0.609  -0.538  -0.316  -0.776  -0.686  -0.480
53    I        -1.029  -0.876  -0.894  -1.470  -1.316  -1.187  -1.253  -1.031  -0.979
54    I         0.189   0.045  -0.102   0.248   0.088  -0.143   0.178  -0.039  -0.311
55    S        -1.029  -0.906  -0.899  -1.082  -0.922  -0.854  -1.253  -1.080  -0.987
56    H        -0.189  -0.203  -0.181   0.016  -0.028  -0.051  -0.418  -0.448  -0.451
57    M        -0.543  -0.723  -0.866  -0.313  -0.646  -0.968  -0.537  -0.765  -0.940
58    Q         0.189   0.045  -0.102   0.470   0.284   0.009   0.178  -0.039  -0.311
59    T        -0.878  -0.870  -0.876  -0.900  -0.933  -0.984  -1.014  -0.949  -0.954
60    V        -0.878  -1.040  -0.905  -0.937  -1.156  -0.961  -1.014  -1.181  -0.993
61    G         0.189  -0.010  -0.106   0.420   0.166   0.000   0.178  -0.126  -0.319
62    R         0.957   1.007   1.062   1.183   1.242   1.304   1.012   1.077   1.157
63    R        -0.189  -0.329  -0.196  -0.050  -0.357  -0.177  -0.418  -0.670  -0.477
64    A         0.189   0.045  -0.102   0.329   0.158  -0.050   0.178  -0.039  -0.311
65    H         0.189  -0.010  -0.106   0.529   0.253   0.040   0.178  -0.126  -0.319
66    I        -0.543  -0.874  -0.882  -0.482  -0.970  -1.050  -0.537  -0.956  -0.960
67    V         0.957   1.007   1.062   1.002   1.070   1.151   1.012   1.077   1.157
68    N         0.957   1.007   1.062   1.007   1.098   1.156   1.012   1.077   1.157
69    L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
70    D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
71    P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
72    A         0.957   1.007   1.062   0.972   1.046   1.127   1.012   1.077   1.157
73    A         0.957   1.007   1.062   0.972   1.046   1.127   1.012   1.077   1.157
74    E         0.189   0.323  -0.082   0.170   0.365  -0.201   0.178   0.369  -0.276
75    A        -1.516  -1.612  -1.432  -1.439  -1.555  -1.322  -1.491  -1.518  -1.277
76    T        -1.736  -1.586  -1.444  -1.696  -1.482  -1.272  -1.729  -1.510  -1.289
77    K        -0.392  -0.158  -0.155  -0.695  -0.297  -0.301  -0.776  -0.370  -0.404
78    Y        -0.543  -0.874  -0.882  -0.117  -0.556  -0.579  -0.537  -0.956  -0.960
79    E         0.189  -0.010  -0.106   0.184  -0.058  -0.202   0.178  -0.126  -0.319
80    F        -0.189  -0.329  -0.196  -0.185  -0.457  -0.259  -0.418  -0.670  -0.477
81    T         0.189  -0.010  -0.106   0.408   0.103  -0.103   0.178  -0.126  -0.319
82    I        -0.878  -1.075  -0.913  -1.023  -1.384  -1.155  -1.014  -1.230  -1.002
83    D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
84    I         0.189   0.323  -0.082   0.232   0.427  -0.153   0.178   0.369  -0.276
85    R        -0.189  -0.235  -0.184  -0.031  -0.142  -0.117  -0.418  -0.503  -0.456
86    D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
87    L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
88    I         0.957   1.007   1.062   0.907   1.001   1.072   1.012   1.077   1.157
89    S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
90    L         0.189   0.045  -0.102  -0.147  -0.319  -0.512   0.178  -0.039  -0.311
91    D        -1.736  -1.615  -1.438  -1.907  -1.739  -1.429  -1.729  -1.539  -1.284
92    D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
93    V         0.957   1.007   1.062   1.002   1.070   1.151   1.012   1.077   1.157
94    M         0.957   1.007   1.062   1.115   1.174   1.247   1.012   1.077   1.157
95    E         0.189  -0.010  -0.106   0.147  -0.122  -0.306   0.178  -0.126  -0.319
96    E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
97    M        -0.878  -0.694  -0.881  -0.900  -0.701  -0.997  -1.014  -0.788  -0.963
98    D        -1.516  -1.455  -1.421  -1.621  -1.547  -1.421  -1.491  -1.389  -1.268
99    L         0.189   0.045  -0.102  -0.109  -0.266  -0.406   0.178  -0.039  -0.311
100   G         0.957   1.007   1.062   1.071   1.143   1.210   1.012   1.077   1.157
101   P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
102   N         0.957   1.007   1.062   1.007   1.098   1.156   1.012   1.077   1.157
103   G         0.957   1.007   1.062   1.071   1.143   1.210   1.012   1.077   1.157
104   A        -1.029  -0.692  -0.873  -1.096  -0.571  -0.822  -1.253  -0.785  -0.952
105   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
106   I        -0.543  -0.424  -0.836  -0.414  -0.236  -0.813  -0.537  -0.367  -0.902
107   Y         0.957   1.007   1.062   1.149   1.209   1.276   1.012   1.077   1.157
108   C         0.957   1.007   1.062   1.224   1.287   1.339   1.012   1.077   1.157
109   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
110   E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
111   Y        -0.392  -0.158  -0.155  -0.481  -0.106  -0.121  -0.776  -0.370  -0.404
112   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
113   L        -0.456  -0.350  -0.193  -0.957  -0.714  -0.458  -0.895  -0.707  -0.472
114   K        -1.736  -1.592  -1.443  -1.799  -1.604  -1.343  -1.729  -1.515  -1.288
115   N         0.957   1.007   1.062   1.007   1.098   1.156   1.012   1.077   1.157
116   L         0.189   0.227  -0.092  -0.114  -0.040  -0.408   0.178   0.235  -0.294
117   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
118   W         0.189  -0.010  -0.106   0.607   0.327   0.100   0.178  -0.126  -0.319
119   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
120   D        -1.231  -1.508  -1.432  -1.144  -1.543  -1.425  -1.133  -1.413  -1.277
121   E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
122   E         0.189  -0.010  -0.106   0.165  -0.089  -0.257   0.178  -0.126  -0.319
123   I        -0.189  -0.270  -0.190  -0.459  -0.655  -0.596  -0.418  -0.564  -0.466
124   G         0.189  -0.010  -0.106   0.374   0.085  -0.129   0.178  -0.126  -0.319
125   D        -0.543  -0.723  -0.866  -0.515  -0.780  -1.007  -0.537  -0.765  -0.940
126   F        -1.029  -1.074  -0.901  -1.081  -1.185  -0.955  -1.253  -1.229  -0.988
127   N        -1.231  -1.508  -1.432  -1.022  -1.447  -1.395  -1.133  -1.413  -1.277
128   D        -0.189  -0.329  -0.196  -0.417  -0.708  -0.480  -0.418  -0.670  -0.477
129   E         0.189   0.045  -0.102   0.147  -0.037  -0.297   0.178  -0.039  -0.311
130   Y         0.957   1.007   1.062   1.149   1.209   1.276   1.012   1.077   1.157
131   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   I         0.957   1.007   1.062   0.907   1.001   1.072   1.012   1.077   1.157
134   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
135   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
136   C        -0.189  -0.329  -0.196   0.027  -0.260  -0.084  -0.418  -0.670  -0.477
137   P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
138   G         0.957   1.007   1.062   1.071   1.143   1.210   1.012   1.077   1.157
139   Q         0.957   1.007   1.062   1.139   1.212   1.267   1.012   1.077   1.157
140   I         0.957   1.007   1.062   0.907   1.001   1.072   1.012   1.077   1.157
141   E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
142   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
143   Y         0.957   1.007   1.062   1.149   1.209   1.276   1.012   1.077   1.157
144   T         0.957   1.007   1.062   1.105   1.162   1.239   1.012   1.077   1.157
145   H         0.957   1.007   1.062   1.201   1.269   1.320   1.012   1.077   1.157
146   I        -0.189  -0.242  -0.185  -0.312  -0.401  -0.335  -0.418  -0.515  -0.458
147   P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
148   V        -0.189  -0.329  -0.196  -0.251  -0.540  -0.344  -0.418  -0.670  -0.477
149   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
150   P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
151   N        -0.878  -0.825  -0.872  -0.756  -0.660  -0.787  -1.014  -0.889  -0.949
152   I        -0.189  -0.329  -0.196  -0.459  -0.808  -0.618  -0.418  -0.670  -0.477
153   V         0.189   0.045  -0.102   0.313   0.116  -0.153   0.178  -0.039  -0.311
154   R        -0.189  -0.270  -0.190  -0.031  -0.206  -0.129  -0.418  -0.564  -0.466
155   H         0.189  -0.010  -0.106   0.529   0.253   0.040   0.178  -0.126  -0.319
156   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
157   T        -0.189  -0.216  -0.184  -0.057  -0.121  -0.121  -0.418  -0.470  -0.456
158   Q        -2.442  -2.181  -2.171  -1.980  -1.671  -1.636  -1.968  -1.687  -1.560
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   Q        -2.442  -2.420  -2.192  -2.109  -2.103  -1.850  -1.968  -1.880  -1.573
162   L         0.189   0.227  -0.092  -0.114  -0.040  -0.408   0.178   0.235  -0.294
163   N        -0.543  -0.723  -0.866  -0.347  -0.610  -0.863  -0.537  -0.765  -0.940
164   F         0.189  -0.010  -0.106   0.344   0.066  -0.136   0.178  -0.126  -0.319
165   N        -0.878  -0.963  -0.911  -0.777  -0.904  -0.815  -1.014  -1.127  -1.000
166   L         0.189   0.045  -0.102  -0.130  -0.294  -0.462   0.178  -0.039  -0.311
167   C         0.957   1.007   1.062   1.224   1.287   1.339   1.012   1.077   1.157
168   A         0.957   1.007   1.062   0.972   1.046   1.127   1.012   1.077   1.157
169   T        -1.231  -1.508  -1.432  -0.850  -1.298  -1.181  -1.133  -1.413  -1.277
170   Y         0.957   1.007   1.062   1.149   1.209   1.276   1.012   1.077   1.157
171   L         0.189   0.227  -0.092  -0.147  -0.069  -0.496   0.178   0.235  -0.294
172   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
173   E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
174   A         0.189   0.045  -0.102   0.295   0.107  -0.142   0.178  -0.039  -0.311
175   P        -0.543  -0.874  -0.882  -0.281  -0.729  -0.754  -0.537  -0.956  -0.960
176   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
177   V        -0.543  -0.592  -0.848  -0.428  -0.545  -1.014  -0.537  -0.597  -0.917
178   I        -0.878  -0.963  -0.911  -1.023  -1.186  -1.149  -1.014  -1.127  -1.000
179   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
180   S        -1.516  -1.107  -1.390  -1.261  -0.673  -1.102  -1.491  -0.979  -1.235
181   S        -1.231  -1.508  -1.432  -0.978  -1.397  -1.285  -1.133  -1.413  -1.277
182   K         0.957   1.007   1.062   1.055   1.126   1.196   1.012   1.077   1.157
183   F         0.189  -0.010  -0.106   0.379   0.120  -0.041   0.178  -0.126  -0.319
184   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
185   S        -0.189  -0.329  -0.196  -0.239  -0.520  -0.313  -0.418  -0.670  -0.477
186   G         0.957   1.007   1.062   1.071   1.143   1.210   1.012   1.077   1.157
187   A        -0.878  -1.075  -0.913  -0.878  -1.192  -0.939  -1.014  -1.230  -1.002
188   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
189   S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
190   A         0.957   1.007   1.062   0.972   1.046   1.127   1.012   1.077   1.157
191   M         0.957   1.007   1.062   1.115   1.174   1.247   1.012   1.077   1.157
192   S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
193   A         0.957   1.007   1.062   0.972   1.046   1.127   1.012   1.077   1.157
194   M         0.957   1.007   1.062   1.115   1.174   1.247   1.012   1.077   1.157
195   I         0.189   0.045  -0.102   0.232   0.063  -0.188   0.178  -0.039  -0.311
196   L        -0.189  -0.329  -0.196  -0.625  -0.814  -0.518  -0.418  -0.670  -0.477
197   L         0.189   0.045  -0.102  -0.114  -0.275  -0.421   0.178  -0.039  -0.311
198   E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
199   L        -0.878  -0.963  -0.911  -1.265  -1.359  -1.134  -1.014  -1.127  -1.000
200   P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
201   H         0.957   1.007   1.062   1.201   1.269   1.320   1.012   1.077   1.157
202   I         0.957   1.007   1.062   0.907   1.001   1.072   1.012   1.077   1.157
203   N         0.957   1.007   1.062   1.007   1.098   1.156   1.012   1.077   1.157
204   V        -0.878  -0.825  -0.872  -1.023  -0.938  -1.087  -1.014  -0.889  -0.949
205   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
206   S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
207   K         0.957   1.007   1.062   1.055   1.126   1.196   1.012   1.077   1.157
208   L        -1.249  -1.008  -0.909  -1.713  -1.174  -1.084  -1.491  -1.139  -0.996
209   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
210   L         0.189   0.408  -0.077  -0.114   0.166  -0.386   0.178   0.482  -0.268
211   I        -1.029  -1.075  -0.904  -1.302  -1.378  -1.130  -1.253  -1.242  -0.993
212   K         0.957   1.007   1.062   1.055   1.126   1.196   1.012   1.077   1.157
213   G        -0.878  -0.765  -0.885  -0.974  -0.849  -0.942  -1.014  -0.879  -0.968
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   D        -1.869  -1.863  -1.837  -1.763  -1.748  -1.697  -1.610  -1.579  -1.445
217   I        -1.736  -1.486  -1.434  -1.708  -1.400  -1.238  -1.729  -1.430  -1.281
218   N        -2.575  -2.490  -2.194  -2.287  -2.124  -1.721  -2.087  -1.928  -1.574
219   K         0.957   1.007   1.062   1.055   1.126   1.196   1.012   1.077   1.157
220   K        -0.543  -0.675  -0.860  -0.262  -0.452  -0.732  -0.537  -0.698  -0.933
221   K        -2.089  -1.894  -1.833  -2.085  -1.844  -1.680  -1.849  -1.603  -1.442
222   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
223   K         0.957   1.007   1.062   1.055   1.126   1.196   1.012   1.077   1.157
224   R        -0.456  -0.372  -0.199  -0.547  -0.423  -0.154  -0.895  -0.749  -0.484
225   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
226   L         0.189  -0.010  -0.106  -0.147  -0.401  -0.519   0.178  -0.126  -0.319
227   N         0.189  -0.010  -0.106   0.346   0.102  -0.079   0.178  -0.126  -0.319
228   P         0.189   0.045  -0.102   0.359   0.180  -0.061   0.178  -0.039  -0.311
229   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
230   A        -0.878  -0.870  -0.876  -0.823  -0.770  -0.815  -1.014  -0.949  -0.954
231   M        -0.878  -0.870  -0.876  -1.240  -1.204  -1.118  -1.014  -0.949  -0.954
232   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
233   L         0.189   0.227  -0.092  -0.114  -0.040  -0.408   0.178   0.235  -0.294
234   M        -2.575  -2.403  -2.184  -2.461  -2.330  -1.920  -2.087  -1.871  -1.568
235   E        -2.442  -2.134  -2.162  -2.332  -1.902  -1.918  -1.968  -1.645  -1.553
236   T        -2.442  -2.153  -2.164  -2.278  -1.945  -1.852  -1.968  -1.668  -1.554
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   M        -2.606  -2.427  -2.190  -2.692  -2.466  -2.100  -2.102  -1.886  -1.572
252   N        -1.029  -0.892  -0.892  -1.252  -1.043  -1.024  -1.253  -1.057  -0.980
253   Q        -2.089  -1.876  -1.833  -1.988  -1.689  -1.651  -1.849  -1.597  -1.443
254   A        -2.575  -2.366  -2.181  -2.338  -1.984  -1.752  -2.087  -1.839  -1.566
255   S        -2.089  -1.905  -1.834  -2.049  -1.755  -1.749  -1.849  -1.612  -1.443
256   N         0.189  -0.010  -0.106   0.310   0.040  -0.178   0.178  -0.126  -0.319
257   P         0.957   1.007   1.062   1.020   1.098   1.167   1.012   1.077   1.157
258   K         0.189  -0.010  -0.106   0.398   0.141  -0.029   0.178  -0.126  -0.319
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
270   L        -1.516  -1.424  -1.414  -1.361  -1.198  -1.317  -1.491  -1.338  -1.259
271   R        -2.089  -2.015  -1.843  -1.789  -1.724  -1.433  -1.849  -1.717  -1.451
272   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
273   N         0.189   0.323  -0.082   0.346   0.536  -0.038   0.178   0.369  -0.276
274   Q        -2.442  -2.372  -2.188  -2.132  -2.064  -1.872  -1.968  -1.850  -1.570
275   C        -1.029  -0.884  -0.894  -1.021  -0.823  -0.792  -1.253  -1.044  -0.981
276   I         0.189  -0.010  -0.106   0.232  -0.018  -0.196   0.178  -0.126  -0.319
277   A        -0.543  -0.675  -0.860  -0.351  -0.538  -0.808  -0.537  -0.698  -0.933
278   N        -0.189  -0.329  -0.196  -0.172  -0.398  -0.209  -0.418  -0.670  -0.477
279   L         0.189   0.227  -0.092  -0.114  -0.040  -0.408   0.178   0.235  -0.294
280   V        -0.878  -1.075  -0.913  -0.969  -1.365  -1.152  -1.014  -1.230  -1.002
281   D        -0.189  -0.270  -0.190  -0.417  -0.589  -0.467  -0.418  -0.564  -0.466
282   D         0.189  -0.010  -0.106   0.192  -0.072  -0.196   0.178  -0.126  -0.319
283   F         0.957   1.007   1.062   1.034   1.104   1.178   1.012   1.077   1.157
284   G        -0.543  -0.874  -0.882  -0.272  -0.751  -0.818  -0.537  -0.956  -0.960
285   M         0.957   1.007   1.062   1.115   1.174   1.247   1.012   1.077   1.157
286   V         0.957   1.007   1.062   1.002   1.070   1.151   1.012   1.077   1.157
287   Q        -0.543  -0.874  -0.882  -0.204  -0.687  -0.773  -0.537  -0.956  -0.960
288   F         0.189  -0.010  -0.106   0.379   0.120  -0.041   0.178  -0.126  -0.319
289   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
290   P         0.189  -0.010  -0.106   0.352   0.092  -0.089   0.178  -0.126  -0.319
291   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
292   E        -0.392  -0.338  -0.195  -0.805  -0.723  -0.480  -0.776  -0.686  -0.476
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   S        -1.029  -0.756  -0.878  -1.156  -0.747  -0.881  -1.253  -0.878  -0.960
295   N        -1.516  -1.617  -1.434  -1.354  -1.467  -1.222  -1.491  -1.524  -1.278
296   N        -0.392  -0.338  -0.195  -0.659  -0.581  -0.370  -0.776  -0.686  -0.476
297   P        -1.162  -1.091  -0.927  -1.338  -1.284  -1.020  -1.372  -1.259  -1.019
298   D        -1.029  -0.877  -0.890  -1.314  -1.095  -0.994  -1.253  -1.033  -0.976
299   S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
300   I         0.189   0.375  -0.078   0.313   0.549  -0.108   0.178   0.439  -0.270
301   E        -1.736  -1.720  -1.446  -1.875  -1.804  -1.406  -1.729  -1.632  -1.291
302   T        -0.878  -1.055  -0.912  -0.730  -1.031  -0.805  -1.014  -1.211  -1.001
303   I         0.189   0.045  -0.102   0.232   0.063  -0.188   0.178  -0.039  -0.311
304   L         0.957   1.007   1.062   0.545   0.634   0.766   1.012   1.077   1.157
305   S         0.957   1.007   1.062   0.994   1.065   1.145   1.012   1.077   1.157
306   Y         0.957   1.007   1.062   1.149   1.209   1.276   1.012   1.077   1.157
307   V        -0.878  -0.670  -0.860  -1.023  -0.673  -1.063  -1.014  -0.690  -0.934
308   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
309   D         0.957   1.007   1.062   0.853   0.921   1.026   1.012   1.077   1.157
310   I        -1.231  -1.403  -1.418  -0.968  -1.221  -1.256  -1.133  -1.314  -1.263
311   T         0.189  -0.010  -0.106   0.416   0.123  -0.082   0.178  -0.126  -0.319
312   Q         0.957   1.007   1.062   1.139   1.212   1.267   1.012   1.077   1.157
313   W         0.189  -0.010  -0.106   0.623   0.353   0.144   0.178  -0.126  -0.319
314   A        -1.516  -1.637  -1.436  -1.393  -1.505  -1.212  -1.491  -1.544  -1.281
315   E         0.189   0.227  -0.092   0.147   0.222  -0.279   0.178   0.235  -0.294
316   G        -1.869  -1.729  -1.818  -1.656  -1.508  -1.621  -1.610  -1.433  -1.429
317   Q         0.957   1.007   1.062   1.139   1.212   1.267   1.012   1.077   1.157
318   E         0.957   1.007   1.062   0.845   0.935   1.019   1.012   1.077   1.157
319   Q        -0.189   0.051  -0.122  -0.159   0.200  -0.081  -0.418  -0.030  -0.346
320   K         0.189  -0.010  -0.106   0.405   0.149  -0.012   0.178  -0.126  -0.319
321   E         0.189   0.045  -0.102   0.147  -0.037  -0.297   0.178  -0.039  -0.311
322   P         0.189  -0.010  -0.106   0.282  -0.030  -0.287   0.178  -0.126  -0.319
323   N        -1.646  -1.315  -1.418  -1.547  -1.048  -1.191  -1.635  -1.214  -1.263
324   D        -0.543  -0.349  -0.833  -0.514  -0.261  -0.949  -0.537  -0.277  -0.898
325   Q        -1.029  -0.986  -0.892  -1.137  -1.017  -0.849  -1.253  -1.112  -0.976
326   I        -1.395  -1.542  -1.442  -1.356  -1.594  -1.447  -1.323  -1.457  -1.286
327   D        -0.878  -0.670  -0.860  -1.056  -0.697  -1.002  -1.014  -0.690  -0.934
328   V        -2.575  -2.473  -2.191  -2.734  -2.522  -2.152  -2.087  -1.916  -1.573
329   E        -1.029  -0.901  -0.896  -1.352  -1.173  -1.064  -1.253  -1.072  -0.983
330   E        -1.029  -0.850  -0.892  -1.354  -1.130  -1.069  -1.253  -1.032  -0.980
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.395  -1.011  -1.381  -1.456  -0.907  -1.461  -1.323  -0.843  -1.225
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06543
Output conservation file - output/Q06543
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
