1     M         1.978   1.995   2.076   2.218   2.243   2.362   2.225   2.252   2.383
2     I         1.221   1.147   1.078   1.132   1.041   0.936   1.267   1.137   0.980
3     C         1.978   1.995   2.076   2.235   2.259   2.380   2.225   2.252   2.383
4     I         0.873   0.845   0.853   0.582   0.528   0.511   0.629   0.566   0.530
5     T         0.507   0.598   0.346   0.830   0.954   0.603   0.469   0.606   0.211
6     C         1.978   1.995   2.076   2.235   2.259   2.380   2.225   2.252   2.383
7     M        -0.381  -0.332  -0.369  -0.119  -0.054  -0.098  -0.488  -0.431  -0.456
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     R        -1.251  -1.205  -1.197  -0.736  -0.679  -0.647  -0.967  -0.922  -0.885
10    P        -0.747  -0.776  -0.802  -0.225  -0.267  -0.297  -0.648  -0.677  -0.687
11    V         0.213   0.219   0.178   0.046   0.052  -0.018  -0.009   0.001  -0.063
12    D         0.213   0.236   0.188   0.393   0.430   0.346  -0.009   0.026  -0.048
13    S         0.213   0.219   0.178   0.250   0.257   0.212  -0.009   0.001  -0.063
14    L         1.978   1.995   2.076   1.574   1.597   1.714   2.225   2.252   2.383
15    Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
16    T        -0.153  -0.123  -0.287   0.046   0.086  -0.176  -0.169  -0.128  -0.339
17    V        -1.251  -1.242  -1.205  -1.006  -0.984  -0.949  -0.967  -0.956  -0.892
18    Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    S         0.213   0.157   0.162   0.210   0.145   0.157  -0.009  -0.082  -0.086
22    N        -0.519  -0.500  -0.467  -0.456  -0.439  -0.358  -0.648  -0.626  -0.567
23    D        -0.153  -0.208  -0.293   0.208   0.121  -0.012  -0.169  -0.241  -0.346
24    H        -0.015  -0.002   0.062   0.027   0.043   0.141  -0.329  -0.312  -0.229
25    I         1.221   1.229   1.091   1.113   1.129   0.925   1.267   1.280   1.007
26    Q        -0.015   0.008   0.067   0.073   0.110   0.192  -0.329  -0.295  -0.221
27    L         1.978   1.995   2.076   1.574   1.597   1.714   2.225   2.252   2.383
28    T         0.507   0.435   0.311   0.724   0.624   0.437   0.469   0.359   0.156
29    D        -1.251  -1.274  -1.223  -0.896  -0.928  -0.865  -0.967  -0.983  -0.906
30    C         1.978   1.995   2.076   2.235   2.259   2.380   2.225   2.252   2.383
31    P        -0.015  -0.021   0.046  -0.011  -0.029   0.056  -0.329  -0.339  -0.252
32    Y        -0.381  -0.357  -0.380  -0.229  -0.195  -0.216  -0.488  -0.468  -0.471
33    C         1.978   1.995   2.076   2.235   2.259   2.380   2.225   2.252   2.383
34    Q        -1.251  -1.242  -1.208  -0.777  -0.768  -0.702  -0.967  -0.956  -0.894
35    E        -0.885  -0.852  -0.842  -0.595  -0.549  -0.520  -0.807  -0.774  -0.734
36    T        -0.885  -0.856  -0.855  -0.836  -0.796  -0.790  -0.807  -0.778  -0.746
37    V         0.717   0.743   0.809   0.589   0.635   0.723   0.310   0.357   0.437
38    D         1.978   1.995   2.076   2.185   2.211   2.329   2.225   2.252   2.383
39    K         1.221   1.229   1.091   1.411   1.431   1.254   1.267   1.280   1.007
40    Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
41    V         0.717   0.743   0.809   0.298   0.339   0.430   0.310   0.357   0.437
42    E         1.978   1.995   2.076   2.154   2.180   2.298   2.225   2.252   2.383
43    I        -0.885  -0.898  -0.866  -1.001  -1.042  -0.967  -0.807  -0.815  -0.755
44    D         1.978   1.995   2.076   2.185   2.211   2.329   2.225   2.252   2.383
45    N        -0.747  -0.776  -0.802  -0.388  -0.447  -0.470  -0.648  -0.678  -0.687
46    V         1.978   1.995   2.076   1.951   1.969   2.093   2.225   2.252   2.383
47    L         0.873   0.887   0.883   0.292   0.313   0.269   0.629   0.650   0.594
48    L         0.873   0.845   0.873   0.292   0.234   0.249   0.629   0.565   0.572
49    F         0.873   0.852   0.852   0.840   0.794   0.754   0.629   0.580   0.528
50    I         0.213   0.157   0.162  -0.161  -0.228  -0.247  -0.009  -0.082  -0.086
51    D         1.978   1.995   2.076   2.185   2.211   2.329   2.225   2.252   2.383
52    L         0.213   0.157   0.162  -0.351  -0.432  -0.439  -0.009  -0.082  -0.086
53    L         0.507   0.448   0.314   0.218   0.126  -0.057   0.469   0.378   0.161
54    L         1.978   1.995   2.076   1.574   1.597   1.714   2.225   2.252   2.383
55    L         1.221   1.147   1.078   0.926   0.838   0.756   1.267   1.137   0.980
56    K         1.978   1.995   2.076   2.059   2.089   2.202   2.225   2.252   2.383
57    A        -0.381  -0.329  -0.371  -0.088  -0.009  -0.060  -0.488  -0.425  -0.457
58    G         0.717   0.743   0.809   0.798   0.839   0.934   0.310   0.357   0.437
59    A         1.221   1.147   1.078   1.460   1.355   1.247   1.267   1.137   0.980
60    Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
61    R         1.221   1.229   1.090   1.508   1.520   1.327   1.267   1.279   1.005
62    H         1.978   1.995   2.076   2.265   2.293   2.410   2.225   2.252   2.383
63    L         1.221   1.259   1.090   0.926   0.975   0.774   1.267   1.330   1.005
64    V        -0.381  -0.421  -0.398  -0.478  -0.569  -0.520  -0.488  -0.528  -0.489
65    F         0.717   0.728   0.796   0.570   0.586   0.678   0.310   0.324   0.411
66    N         1.978   1.995   2.076   2.129   2.155   2.272   2.225   2.252   2.383
67    A        -1.251  -1.205  -1.197  -1.369  -1.300  -1.304  -0.967  -0.922  -0.885
68    L         0.213   0.219   0.178  -0.145  -0.136  -0.158  -0.009   0.001  -0.063
69    E        -0.153  -0.209  -0.300   0.132   0.040  -0.118  -0.169  -0.242  -0.355
70    L        -1.251  -1.274  -1.223  -1.267  -1.270  -1.158  -0.967  -0.983  -0.906
71    H        -1.251  -1.242  -1.219  -0.737  -0.730  -0.676  -0.967  -0.956  -0.903
72    L         0.213   0.188   0.165  -0.145  -0.179  -0.172  -0.009  -0.054  -0.083
73    S        -0.885  -0.897  -0.848  -0.836  -0.847  -0.786  -0.807  -0.814  -0.740
74    K        -0.747  -0.794  -0.804  -0.508  -0.571  -0.602  -0.648  -0.697  -0.689
75    Y        -1.616  -1.608  -1.538  -1.081  -1.063  -0.959  -1.127  -1.116  -1.024
76    P        -0.905  -0.929  -0.880  -0.610  -0.657  -0.592  -0.816  -0.836  -0.766
77    K        -0.905  -0.900  -0.871  -0.670  -0.666  -0.626  -0.816  -0.808  -0.757
78    R        -0.905  -0.894  -0.876  -0.514  -0.503  -0.448  -0.816  -0.802  -0.762
79    K        -0.905  -0.929  -0.880  -0.620  -0.645  -0.567  -0.816  -0.836  -0.766
80    A         0.057   0.113   0.100  -0.047   0.047   0.002  -0.219  -0.134  -0.170
81    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    C        -0.995  -0.988  -0.913  -0.714  -0.709  -0.590  -0.903  -0.892  -0.797
89    Q        -0.483  -0.441  -0.438  -0.406  -0.326  -0.367  -0.590  -0.536  -0.527
90    C        -0.483  -0.450  -0.457  -0.618  -0.582  -0.560  -0.590  -0.548  -0.550
91    L        -0.995  -0.988  -0.913  -1.147  -1.111  -1.026  -0.903  -0.892  -0.797
92    R        -0.483  -0.498  -0.446  -0.167  -0.190  -0.111  -0.590  -0.607  -0.537
93    D         0.223   0.258   0.177   0.454   0.506   0.392   0.035   0.088  -0.052
94    Y        -0.583  -0.572  -0.499  -0.391  -0.365  -0.265  -0.708  -0.693  -0.598
95    T        -0.583  -0.572  -0.499  -0.875  -0.877  -0.752  -0.708  -0.693  -0.598
96    Q         0.057   0.061   0.089   0.142   0.153   0.197  -0.219  -0.216  -0.188
97    A         0.057   0.061   0.089  -0.022  -0.032   0.016  -0.219  -0.216  -0.188
98    L        -0.583  -0.572  -0.499  -0.875  -0.839  -0.752  -0.708  -0.693  -0.598
99    L        -0.583  -0.572  -0.499  -0.945  -0.919  -0.822  -0.708  -0.693  -0.598
100   F         0.057   0.076   0.094   0.047   0.076   0.086  -0.219  -0.192  -0.179
101   N         0.223   0.196   0.150   0.331   0.285   0.184   0.035  -0.007  -0.094
102   V        -0.483  -0.506  -0.461  -0.775  -0.823  -0.797  -0.590  -0.616  -0.555
103   K         0.029   0.049   0.086   0.015   0.046   0.108  -0.278  -0.251  -0.200
104   N         0.223   0.196   0.150   0.405   0.360   0.285   0.035  -0.007  -0.094
105   W         0.223   0.196   0.150   0.468   0.424   0.310   0.035  -0.007  -0.094
106   F         0.110   0.118   0.122  -0.237  -0.263  -0.286  -0.165  -0.163  -0.152
107   C        -1.251  -1.248  -1.215  -0.982  -0.981  -0.926  -0.967  -0.962  -0.900
108   K        -0.153  -0.136  -0.291   0.009   0.041  -0.232  -0.169  -0.145  -0.343
109   Y         0.507   0.447   0.311   0.771   0.699   0.531   0.469   0.377   0.157
110   D        -0.381  -0.419  -0.412  -0.047  -0.098  -0.069  -0.488  -0.528  -0.504
111   R        -0.885  -0.865  -0.847  -0.567  -0.546  -0.497  -0.807  -0.784  -0.738
112   L         0.213   0.188   0.169  -0.312  -0.358  -0.395  -0.009  -0.053  -0.078
113   N        -1.251  -1.242  -1.206  -1.115  -1.114  -1.026  -0.967  -0.956  -0.892
114   R         0.507   0.435   0.311   0.859   0.761   0.575   0.469   0.359   0.156
115   L         0.873   0.845   0.853   0.406   0.360   0.368   0.629   0.566   0.530
116   W        -1.251  -1.264  -1.221  -0.843  -0.862  -0.814  -0.967  -0.974  -0.905
117   L        -0.885  -0.909  -0.856  -1.236  -1.276  -1.183  -0.807  -0.824  -0.746
118   L        -0.153  -0.123  -0.287  -0.370  -0.330  -0.536  -0.169  -0.128  -0.339
119   L         0.123   0.140   0.132  -0.422  -0.384  -0.358  -0.169  -0.145  -0.141
120   L        -0.885  -0.904  -0.853  -1.288  -1.313  -1.243  -0.807  -0.820  -0.744
121   S        -0.381  -0.347  -0.380  -0.767  -0.731  -0.739  -0.488  -0.443  -0.469
122   F         1.978   1.995   2.076   2.074   2.098   2.218   2.225   2.252   2.383
123   E         1.221   1.147   1.078   1.489   1.396   1.297   1.267   1.137   0.980
124   I         1.221   1.298   1.103   1.233   1.334   1.047   1.267   1.395   1.028
125   Y         1.221   1.147   1.078   1.357   1.264   1.160   1.267   1.137   0.980
126   L         1.978   1.995   2.076   1.574   1.597   1.714   2.225   2.252   2.383
127   T         0.507   0.462   0.317   0.718   0.646   0.437   0.469   0.398   0.166
128   W         1.221   1.243   1.090   1.606   1.639   1.443   1.267   1.304   1.004
129   V         0.123   0.081   0.129   0.058  -0.003   0.078  -0.169  -0.214  -0.145
130   T        -1.251  -1.274  -1.223  -0.834  -0.858  -0.773  -0.967  -0.983  -0.906
131   E         0.213   0.168   0.166   0.194   0.111   0.054  -0.009  -0.064  -0.084
132   E         1.978   1.995   2.076   2.154   2.180   2.298   2.225   2.252   2.383
133   S        -0.747  -0.682  -0.787  -0.458  -0.356  -0.514  -0.648  -0.573  -0.672
134   K        -0.747  -0.794  -0.804  -0.614  -0.682  -0.738  -0.648  -0.697  -0.689
135   Y         0.057   0.034   0.081   0.052   0.019   0.081  -0.219  -0.260  -0.200
136   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   L         0.029   0.058   0.091  -0.317  -0.260  -0.207  -0.278  -0.240  -0.193
152   S        -0.478  -0.462  -0.451  -0.467  -0.431  -0.437  -0.599  -0.579  -0.547
153   K        -0.905  -0.905  -0.876  -0.512  -0.514  -0.479  -0.816  -0.813  -0.762
154   K        -0.478  -0.494  -0.453  -0.497  -0.517  -0.451  -0.599  -0.612  -0.550
155   L        -0.905  -0.914  -0.880  -1.098  -1.102  -1.010  -0.816  -0.822  -0.766
156   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   I        -0.885  -0.902  -0.851  -1.160  -1.165  -1.067  -0.807  -0.819  -0.742
166   M        -0.519  -0.543  -0.458  -0.514  -0.541  -0.416  -0.648  -0.665  -0.559
167   R        -1.251  -1.268  -1.210  -0.956  -0.982  -0.908  -0.967  -0.978  -0.896
168   N        -1.251  -1.274  -1.223  -1.020  -1.055  -0.994  -0.967  -0.983  -0.906
169   T        -0.381  -0.386  -0.391  -0.781  -0.788  -0.797  -0.488  -0.493  -0.481
170   I         0.507   0.570   0.349   0.184   0.276  -0.057   0.469   0.563   0.216
171   T        -1.616  -1.608  -1.538  -1.056  -1.055  -0.934  -1.127  -1.116  -1.024
172   S        -0.747  -0.683  -0.782  -0.554  -0.447  -0.663  -0.648  -0.574  -0.666
173   K        -0.885  -0.851  -0.852  -0.655  -0.598  -0.602  -0.807  -0.773  -0.743
174   V         0.717   0.718   0.792   0.328   0.314   0.417   0.310   0.303   0.403
175   F        -1.251  -1.211  -1.215  -1.048  -1.007  -0.960  -0.967  -0.927  -0.900
176   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   I        -1.251  -1.242  -1.219  -1.036  -1.000  -0.987  -0.967  -0.956  -0.903
182   Q         1.978   1.995   2.076   2.197   2.221   2.342   2.225   2.252   2.383
183   Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
184   L         0.507   0.520   0.336   0.289   0.308   0.086   0.469   0.490   0.196
185   Y         0.213   0.183   0.178   0.262   0.232   0.203  -0.009  -0.038  -0.064
186   F         1.221   1.147   1.078   1.321   1.206   1.063   1.267   1.137   0.980
187   A        -0.381  -0.317  -0.384  -0.823  -0.747  -0.791  -0.488  -0.414  -0.471
188   S        -0.519  -0.485  -0.458  -0.928  -0.905  -0.852  -0.648  -0.614  -0.558
189   Y        -0.015  -0.022   0.048  -0.242  -0.262  -0.169  -0.329  -0.340  -0.249
190   C        -0.153  -0.123  -0.287   0.101   0.147  -0.178  -0.169  -0.128  -0.339
191   I        -0.885  -0.871  -0.856  -1.279  -1.280  -1.201  -0.807  -0.790  -0.747
192   L        -0.153  -0.186  -0.299  -0.492  -0.545  -0.728  -0.169  -0.213  -0.354
193   D         0.873   0.915   0.901   1.001   1.068   1.028   0.629   0.705   0.630
194   V        -1.251  -1.237  -1.203  -0.841  -0.823  -0.766  -0.967  -0.951  -0.890
195   S        -1.251  -1.242  -1.205  -1.370  -1.356  -1.321  -0.967  -0.956  -0.892
196   L        -0.519  -0.513  -0.457  -0.948  -0.931  -0.841  -0.648  -0.637  -0.557
197   F        -0.381  -0.408  -0.393  -0.631  -0.665  -0.602  -0.488  -0.512  -0.481
198   H         0.213   0.157   0.162   0.504   0.434   0.431  -0.009  -0.082  -0.086
199   T        -1.251  -1.211  -1.215  -1.347  -1.291  -1.287  -0.967  -0.927  -0.900
200   F         0.213   0.265   0.186   0.149   0.226   0.105  -0.009   0.070  -0.049
201   T        -0.885  -0.866  -0.863  -1.046  -1.029  -1.052  -0.807  -0.786  -0.753
202   Q        -0.153  -0.209  -0.300   0.118   0.020  -0.159  -0.169  -0.242  -0.355
203   Y        -0.381  -0.390  -0.397  -0.571  -0.623  -0.619  -0.488  -0.502  -0.489
204   F        -0.885  -0.866  -0.844  -1.118  -1.126  -1.061  -0.807  -0.784  -0.736
205   I        -0.747  -0.693  -0.764  -1.088  -1.004  -1.114  -0.648  -0.585  -0.647
206   L        -1.251  -1.242  -1.208  -1.006  -0.953  -0.958  -0.967  -0.956  -0.894
207   K        -0.885  -0.865  -0.847  -1.166  -1.167  -1.113  -0.807  -0.784  -0.738
208   K        -1.616  -1.608  -1.538  -1.251  -1.236  -1.131  -1.127  -1.116  -1.024
209   L        -0.885  -0.865  -0.844  -0.865  -0.802  -0.768  -0.807  -0.784  -0.736
210   H        -0.885  -0.845  -0.862  -0.466  -0.412  -0.403  -0.807  -0.768  -0.752
211   W         1.978   1.995   2.076   2.255   2.282   2.400   2.225   2.252   2.383
212   K         0.717   0.724   0.798   0.726   0.735   0.834   0.310   0.317   0.414
213   H        -0.478  -0.438  -0.435  -0.396  -0.355  -0.311  -0.599  -0.554  -0.530
214   Y        -1.332  -1.317  -1.252  -1.091  -1.035  -0.970  -1.033  -1.017  -0.929
215   S        -0.905  -0.839  -0.852  -0.833  -0.714  -0.763  -0.816  -0.744  -0.739
216   V        -0.905  -0.853  -0.854  -0.793  -0.718  -0.711  -0.816  -0.759  -0.740
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   S         0.376   0.342   0.262   0.496   0.454   0.320   0.270   0.210   0.080
231   S         0.123   0.129   0.143   0.108   0.111   0.152  -0.169  -0.160  -0.129
232   K        -1.251  -1.274  -1.223  -0.841  -0.862  -0.781  -0.967  -0.983  -0.906
233   D        -1.251  -1.274  -1.223  -0.827  -0.860  -0.787  -0.967  -0.983  -0.906
234   V         0.213   0.236   0.188   0.069   0.102   0.029  -0.009   0.026  -0.048
235   I        -0.015  -0.009   0.051  -0.686  -0.683  -0.590  -0.329  -0.321  -0.245
236   S         0.110   0.129   0.119  -0.279  -0.252  -0.283  -0.165  -0.139  -0.151
237   Y         0.110   0.081   0.108   0.017  -0.025   0.012  -0.165  -0.202  -0.168
238   T        -0.317  -0.329  -0.371  -0.218  -0.235  -0.332  -0.382  -0.396  -0.445
239   I        -0.478  -0.474  -0.444  -1.008  -1.009  -0.942  -0.599  -0.591  -0.540
240   L         1.146   1.145   1.031   0.835   0.836   0.693   1.139   1.134   0.891
241   L        -0.015   0.002   0.058  -0.686  -0.664  -0.583  -0.329  -0.304  -0.235
242   S         1.978   1.995   2.076   1.956   1.978   2.099   2.225   2.252   2.383
243   Y        -0.381  -0.358  -0.382  -0.294  -0.254  -0.258  -0.488  -0.451  -0.467
244   G         0.123   0.140   0.135   0.173   0.181   0.202  -0.169  -0.146  -0.138
245   A        -0.519  -0.511  -0.467  -0.617  -0.611  -0.540  -0.648  -0.635  -0.567
246   K         0.873   0.839   0.854   0.912   0.858   0.863   0.629   0.553   0.533
247   I         0.123   0.081   0.129  -0.422  -0.460  -0.378  -0.169  -0.214  -0.145
248   F         0.873   0.845   0.873   0.701   0.625   0.615   0.629   0.565   0.572
249   P         1.978   1.995   2.076   2.230   2.255   2.375   2.225   2.252   2.383
250   I         1.221   1.147   1.078   1.113   1.015   0.903   1.267   1.137   0.980
251   L         1.221   1.147   1.078   0.899   0.804   0.708   1.267   1.137   0.980
252   M         1.978   1.995   2.076   2.218   2.243   2.362   2.225   2.252   2.383
253   L        -0.153  -0.209  -0.305  -0.488  -0.576  -0.731  -0.169  -0.242  -0.361
254   I         1.978   1.995   2.076   1.807   1.835   1.949   2.225   2.252   2.383
255   W         1.978   1.995   2.076   2.255   2.282   2.400   2.225   2.252   2.383
256   P         0.873   0.845   0.873   1.071   1.021   1.047   0.629   0.565   0.572
257   Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
258   D         1.978   1.995   2.076   2.185   2.211   2.329   2.225   2.252   2.383
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   T        -0.747  -0.794  -0.804  -0.725  -0.841  -0.884  -0.648  -0.697  -0.689
261   L        -0.885  -0.871  -0.854  -1.164  -1.117  -1.075  -0.807  -0.789  -0.744
262   I         0.873   0.902   0.873   0.434   0.490   0.356   0.629   0.680   0.573
263   S         0.213   0.188   0.165   0.212   0.168   0.150  -0.009  -0.054  -0.083
264   M        -0.519  -0.512  -0.464  -0.344  -0.334  -0.260  -0.648  -0.636  -0.564
265   S        -0.519  -0.512  -0.458  -0.445  -0.435  -0.333  -0.648  -0.636  -0.558
266   I         0.213   0.157   0.162  -0.232  -0.319  -0.365  -0.009  -0.083  -0.089
267   I         0.213   0.188   0.169  -0.005  -0.050  -0.062  -0.009  -0.053  -0.078
268   K        -0.381  -0.419  -0.412  -0.171  -0.214  -0.183  -0.488  -0.528  -0.504
269   W         0.213   0.236   0.173   0.208   0.252   0.077  -0.009   0.026  -0.074
270   V         0.213   0.216   0.174   0.002   0.001  -0.050  -0.009  -0.009  -0.073
271   A         0.213   0.199   0.168   0.340   0.295   0.273  -0.009  -0.040  -0.079
272   N         0.213   0.157   0.162   0.226   0.124   0.092  -0.009  -0.082  -0.086
273   L        -0.015  -0.019   0.050  -0.608  -0.599  -0.508  -0.329  -0.335  -0.247
274   Y         0.123   0.081   0.129   0.095   0.042   0.112  -0.169  -0.214  -0.145
275   I        -0.747  -0.785  -0.798  -0.895  -0.949  -1.000  -0.648  -0.687  -0.683
276   I         0.123   0.140   0.132  -0.174  -0.145  -0.135  -0.169  -0.145  -0.141
277   E         1.221   1.147   1.078   1.498   1.408   1.313   1.267   1.137   0.980
278   S         0.873   0.915   0.901   0.916   0.985   0.928   0.629   0.705   0.630
279   L         0.507   0.535   0.333   0.249   0.288   0.019   0.469   0.512   0.190
280   K        -0.747  -0.776  -0.802  -0.344  -0.376  -0.394  -0.648  -0.678  -0.687
281   I         0.507   0.521   0.319   0.351   0.375   0.013   0.469   0.490   0.169
282   V         1.221   1.147   1.078   1.196   1.075   0.938   1.267   1.137   0.980
283   T         1.221   1.242   1.094   1.308   1.338   1.081   1.267   1.302   1.011
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   N         0.123   0.150   0.137   0.101   0.126   0.145  -0.169  -0.136  -0.137
286   L        -1.251  -1.264  -1.206  -1.205  -1.198  -1.094  -0.967  -0.974  -0.893
287   S        -0.747  -0.776  -0.802  -0.420  -0.457  -0.457  -0.648  -0.677  -0.687
288   Y         1.978   1.995   2.076   2.030   2.058   2.173   2.225   2.252   2.383
289   W        -0.747  -0.702  -0.779  -0.470  -0.410  -0.520  -0.648  -0.595  -0.663
290   N        -0.381  -0.336  -0.380  -0.295  -0.231  -0.280  -0.488  -0.436  -0.469
291   I         0.507   0.520   0.332   0.396   0.416   0.107   0.469   0.489   0.189
292   I        -0.747  -0.775  -0.786  -0.644  -0.666  -0.669  -0.648  -0.677  -0.670
293   K        -0.747  -0.682  -0.787  -1.031  -0.937  -1.075  -0.648  -0.573  -0.672
294   I         0.213   0.225   0.187  -0.231  -0.203  -0.303  -0.009   0.011  -0.050
295   F        -0.153  -0.156  -0.282  -0.415  -0.432  -0.593  -0.169  -0.176  -0.333
296   I        -0.885  -0.908  -0.859  -0.962  -1.019  -0.921  -0.807  -0.823  -0.749
297   S        -0.519  -0.505  -0.459  -0.649  -0.621  -0.539  -0.648  -0.630  -0.559
298   V        -0.381  -0.397  -0.394  -0.403  -0.420  -0.400  -0.488  -0.501  -0.482
299   S        -0.747  -0.727  -0.789  -0.812  -0.776  -0.928  -0.648  -0.622  -0.673
300   L        -0.153  -0.136  -0.291  -0.464  -0.441  -0.674  -0.169  -0.145  -0.343
301   L        -0.153  -0.209  -0.305  -0.464  -0.554  -0.695  -0.169  -0.242  -0.361
302   R         0.213   0.248   0.183   0.403   0.455   0.359  -0.009   0.041  -0.058
303   Y        -0.885  -0.908  -0.867  -0.664  -0.699  -0.622  -0.807  -0.824  -0.756
304   F        -0.885  -0.850  -0.846  -1.208  -1.158  -1.114  -0.807  -0.772  -0.738
305   M        -0.381  -0.317  -0.386  -0.609  -0.518  -0.639  -0.488  -0.414  -0.476
306   V        -0.381  -0.369  -0.390  -0.539  -0.537  -0.575  -0.488  -0.475  -0.481
307   K        -0.885  -0.903  -0.846  -0.585  -0.608  -0.515  -0.807  -0.819  -0.738
308   P        -0.885  -0.839  -0.849  -0.897  -0.856  -0.821  -0.807  -0.762  -0.740
309   I         0.213   0.152   0.166  -0.200  -0.289  -0.314  -0.009  -0.091  -0.085
310   L         0.507   0.520   0.336   0.216   0.233  -0.027   0.469   0.490   0.196
311   I        -1.251  -1.274  -1.223  -1.181  -1.189  -1.110  -0.967  -0.983  -0.906
312   V        -0.885  -0.865  -0.847  -1.130  -1.129  -1.055  -0.807  -0.784  -0.738
313   F        -0.885  -0.876  -0.848  -1.297  -1.284  -1.220  -0.807  -0.797  -0.740
314   V         0.213   0.157   0.165  -0.014  -0.092  -0.118  -0.009  -0.082  -0.087
315   A        -0.381  -0.355  -0.389  -0.576  -0.578  -0.565  -0.488  -0.465  -0.477
316   K        -1.616  -1.608  -1.538  -1.362  -1.362  -1.243  -1.127  -1.116  -1.024
317   F        -0.747  -0.785  -0.798  -0.427  -0.479  -0.495  -0.648  -0.687  -0.683
318   N        -1.616  -1.608  -1.538  -1.488  -1.511  -1.369  -1.127  -1.116  -1.024
319   F        -1.251  -1.242  -1.208  -0.693  -0.676  -0.618  -0.967  -0.956  -0.894
320   S        -0.747  -0.794  -0.804  -0.523  -0.582  -0.587  -0.648  -0.697  -0.689
321   V        -0.885  -0.903  -0.855  -0.750  -0.778  -0.689  -0.807  -0.819  -0.746
322   I        -0.885  -0.902  -0.851  -0.991  -1.009  -0.941  -0.807  -0.819  -0.742
323   K        -1.251  -1.211  -1.215  -1.163  -1.074  -1.159  -0.967  -0.927  -0.900
324   N        -0.885  -0.909  -0.857  -0.611  -0.632  -0.542  -0.807  -0.825  -0.747
325   L        -1.251  -1.268  -1.210  -1.459  -1.446  -1.366  -0.967  -0.978  -0.896
326   I        -1.251  -1.274  -1.223  -1.048  -1.054  -0.963  -0.967  -0.983  -0.906
327   H        -1.332  -1.325  -1.252  -0.976  -0.973  -0.854  -1.033  -1.024  -0.929
328   Q         0.110   0.114   0.131   0.109   0.113   0.155  -0.165  -0.163  -0.138
329   E         0.376   0.338   0.244   0.706   0.660   0.523   0.270   0.211   0.053
330   F        -0.478  -0.462  -0.433  -0.469  -0.442  -0.401  -0.599  -0.579  -0.528
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -0.905  -0.891  -0.871  -1.225  -1.216  -1.148  -0.816  -0.799  -0.757
335   I        -1.251  -1.274  -1.223  -1.082  -1.097  -1.001  -0.967  -0.983  -0.906
336   L         1.221   1.229   1.091   0.876   0.888   0.689   1.267   1.280   1.007
337   L         0.213   0.231   0.183  -0.188  -0.162  -0.214  -0.009   0.021  -0.059
338   L        -0.885  -0.882  -0.848  -0.769  -0.744  -0.717  -0.807  -0.802  -0.739
339   Q        -0.153  -0.186  -0.289   0.249   0.190   0.047  -0.169  -0.212  -0.341
340   -        -0.995  -0.988  -0.913  -1.144  -1.122  -1.022  -0.903  -0.892  -0.797
341   -        -0.483  -0.472  -0.452  -0.447  -0.427  -0.415  -0.590  -0.575  -0.544
342   -        -0.995  -0.988  -0.913  -0.697  -0.686  -0.573  -0.903  -0.892  -0.797
343   -        -0.995  -0.988  -0.913  -1.076  -1.049  -0.954  -0.903  -0.892  -0.797
344   -         0.735   0.741   0.806   0.112   0.115   0.182   0.348   0.353   0.431
345   K        -0.381  -0.394  -0.388  -0.163  -0.174  -0.169  -0.488  -0.496  -0.478
346   S        -0.478  -0.489  -0.437  -0.641  -0.691  -0.593  -0.599  -0.608  -0.533
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   G        -0.905  -0.896  -0.865  -0.672  -0.667  -0.609  -0.816  -0.805  -0.752
349   T        -0.905  -0.867  -0.872  -0.679  -0.618  -0.638  -0.816  -0.774  -0.758
350   Y        -0.317  -0.308  -0.362  -0.184  -0.169  -0.238  -0.382  -0.372  -0.433
351   L         0.223   0.160   0.166  -0.112  -0.204  -0.177   0.035  -0.067  -0.070
352   L        -1.251  -1.264  -1.221  -1.300  -1.288  -1.194  -0.967  -0.974  -0.905
353   L        -0.381  -0.388  -0.411  -0.827  -0.836  -0.848  -0.488  -0.499  -0.503
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06541
Output conservation file - output/Q06541
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
