1     M         1.972   1.995   2.190   2.211   2.247   2.558   2.252   2.294   2.641
2     S        -0.451  -0.456  -0.488  -0.444  -0.450  -0.532  -0.535  -0.538  -0.553
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.102  -1.134  -0.939  -1.144  -1.175  -0.898  -1.021  -1.040  -0.825
7     V        -0.970  -0.974  -0.879  -1.110  -1.107  -0.974  -0.915  -0.912  -0.776
8     A        -0.832  -0.780  -0.624  -0.934  -0.841  -0.655  -0.915  -0.863  -0.686
9     D        -1.075  -1.136  -1.124  -0.856  -0.930  -0.898  -0.866  -0.922  -0.862
10    L        -1.156  -1.142  -1.129  -1.097  -1.074  -1.033  -0.960  -0.949  -0.865
11    K        -1.156  -1.206  -1.134  -1.041  -1.121  -1.022  -0.960  -0.998  -0.871
12    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    I        -0.334  -0.326  -0.440  -0.415  -0.404  -0.566  -0.440  -0.428  -0.503
16    H        -0.696  -0.666  -0.991  -0.317  -0.273  -0.721  -0.440  -0.407  -0.726
17    K        -0.147  -0.120  -0.125  -0.273  -0.240  -0.253  -0.393  -0.366  -0.354
18    L        -0.451  -0.418  -0.473  -0.503  -0.464  -0.558  -0.535  -0.503  -0.531
19    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
22    Y         0.192   0.170   0.318   0.064   0.022   0.205  -0.204  -0.234  -0.057
23    G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
24    L         0.764   0.770   0.576   0.739   0.746   0.502   0.740   0.746   0.392
25    M         1.495   1.385   1.339   1.813   1.688   1.633   1.685   1.508   1.365
26    S         0.370   0.391   0.425   0.080   0.110   0.205  -0.015   0.011   0.086
27    L         0.462   0.474   0.459   0.246   0.270   0.285   0.174   0.195   0.153
28    T         1.495   1.533   1.355   1.677   1.723   1.566   1.685   1.747   1.396
29    W         1.030   1.067   0.707   1.498   1.546   1.107   1.166   1.224   0.625
30    R        -0.193  -0.188  -0.130  -0.261  -0.263  -0.222  -0.440  -0.443  -0.362
31    A        -0.174  -0.201  -0.142  -0.362  -0.423  -0.313  -0.440  -0.479  -0.376
32    E        -1.343  -1.304  -1.169  -1.361  -1.285  -1.118  -1.102  -1.069  -0.897
33    P         0.324   0.375   0.109   0.539   0.615   0.229   0.315   0.403   0.003
34    I        -0.522  -0.560  -0.531  -0.511  -0.586  -0.615  -0.582  -0.633  -0.590
35    P         0.324   0.350   0.083   0.488   0.525   0.112   0.315   0.354  -0.037
36    Q        -1.343  -1.291  -1.331  -1.032  -0.960  -1.037  -1.007  -0.962  -0.925
37    S         0.136   0.205  -0.245   0.363   0.446  -0.153   0.268   0.356  -0.227
38    Q         0.157   0.126   0.006   0.323   0.255   0.050   0.032  -0.026  -0.177
39    A         0.764   0.755   0.572   0.789   0.773   0.486   0.740   0.725   0.384
40    F         0.764   0.778   0.572   0.900   0.916   0.595   0.740   0.756   0.385
41    E        -1.226  -1.288  -1.148  -1.288  -1.359  -1.184  -1.007  -1.052  -0.881
42    A        -0.513  -0.526  -0.498  -0.623  -0.635  -0.624  -0.629  -0.636  -0.567
43    M         0.157   0.163   0.005   0.370   0.374   0.088   0.032   0.034  -0.184
44    H        -0.147  -0.101  -0.089  -0.223  -0.172  -0.097  -0.393  -0.346  -0.307
45    R        -0.710  -0.699  -0.586  -0.763  -0.742  -0.578  -0.818  -0.805  -0.654
46    V         0.800   0.821   0.989   0.464   0.489   0.718   0.363   0.392   0.595
47    V        -0.063  -0.042  -0.083  -0.276  -0.256  -0.330  -0.251  -0.233  -0.288
48    E        -0.174  -0.163  -0.126  -0.416  -0.405  -0.328  -0.440  -0.428  -0.359
49    L        -1.531  -1.499  -1.391  -1.338  -1.276  -1.179  -1.149  -1.120  -0.968
50    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    H         0.582   0.629   0.511   0.593   0.664   0.499   0.410   0.484   0.268
56    K        -1.343  -1.316  -1.190  -1.384  -1.321  -1.178  -1.102  -1.085  -0.915
57    A        -0.513  -0.598  -0.524  -0.606  -0.728  -0.660  -0.629  -0.705  -0.591
58    F        -0.193  -0.172  -0.121  -0.291  -0.254  -0.205  -0.440  -0.406  -0.343
59    F         0.004   0.007  -0.049   0.110   0.121   0.047  -0.251  -0.244  -0.264
60    N         1.217   1.185   1.163   1.352   1.303   1.238   1.213   1.146   0.992
61    V        -0.288  -0.288  -0.170  -0.609  -0.606  -0.432  -0.582  -0.579  -0.413
62    G         1.495   1.490   1.351   1.551   1.557   1.391   1.685   1.681   1.388
63    E         1.972   1.995   2.190   1.914   1.941   2.255   2.252   2.294   2.641
64    F         1.972   1.995   2.190   2.049   2.083   2.393   2.252   2.294   2.641
65    Y         1.972   1.995   2.190   2.159   2.188   2.505   2.252   2.294   2.641
66    G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
67    P        -1.789  -1.764  -1.751  -1.426  -1.414  -1.459  -1.149  -1.135  -1.055
68    D        -0.851  -0.911  -0.827  -0.808  -0.889  -0.786  -0.818  -0.862  -0.735
69    -         0.259   0.247   0.363   0.065   0.070   0.206  -0.118  -0.110   0.015
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    F        -1.531  -1.483  -1.390  -1.310  -1.263  -1.082  -1.149  -1.109  -0.969
72    I        -1.156  -1.112  -1.099  -1.167  -1.101  -1.134  -0.960  -0.918  -0.844
73    N         0.764   0.804   0.563   0.952   1.005   0.643   0.740   0.800   0.366
74    L         0.576   0.642   0.174   0.703   0.781   0.223   0.693   0.785   0.103
75    S        -1.075  -1.072  -1.088  -0.883  -0.861  -0.900  -0.866  -0.855  -0.823
76    Y         1.030   1.058   0.703   1.067   1.103   0.677   1.166   1.210   0.619
77    V         0.345   0.361   0.380   0.072   0.094   0.062   0.079   0.103   0.062
78    H        -1.201  -1.214  -1.141  -1.126  -1.151  -1.009  -1.007  -1.014  -0.880
79    D        -0.513  -0.479  -0.487  -0.420  -0.371  -0.376  -0.629  -0.594  -0.554
80    F         0.800   0.823   0.989   0.695   0.727   0.949   0.363   0.395   0.595
81    F         0.764   0.755   0.572   0.903   0.893   0.614   0.740   0.725   0.384
82    A        -0.817  -0.848  -0.835  -0.878  -0.908  -0.903  -0.771  -0.799  -0.739
83    K        -0.101  -0.064  -0.363  -0.006   0.037  -0.430  -0.063  -0.021  -0.393
84    Y         0.764   0.648   0.552   1.049   0.904   0.745   0.740   0.571   0.351
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    P         1.972   1.995   2.190   2.034   2.064   2.378   2.252   2.294   2.641
87    D         0.087   0.064  -0.054   0.071   0.027  -0.182  -0.015  -0.058  -0.245
88    L        -0.513  -0.543  -0.486  -0.643  -0.676  -0.611  -0.629  -0.647  -0.553
89    R        -0.513  -0.591  -0.523  -0.533  -0.636  -0.538  -0.629  -0.699  -0.590
90    K        -0.513  -0.451  -0.494  -0.622  -0.541  -0.595  -0.629  -0.570  -0.564
91    D        -0.288  -0.255  -0.662   0.037   0.078  -0.439  -0.110  -0.069  -0.535
92    V         0.764   0.755   0.572   0.809   0.793   0.489   0.740   0.725   0.384
93    V        -0.710  -0.716  -0.576  -0.893  -0.901  -0.707  -0.818  -0.823  -0.646
94    I         0.758   0.779   0.972   0.265   0.288   0.571   0.268   0.295   0.555
95    S         1.030   1.010   0.697   1.189   1.171   0.813   1.166   1.140   0.609
96    C        -0.193  -0.157  -0.132  -0.282  -0.238  -0.211  -0.440  -0.397  -0.358
97    K         1.972   1.995   2.190   1.916   1.947   2.258   2.252   2.294   2.641
98    G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
99    G         0.192   0.207   0.327  -0.068  -0.052   0.138  -0.204  -0.192  -0.044
100   A        -1.531  -1.497  -1.394  -1.494  -1.446  -1.311  -1.149  -1.130  -0.974
101   D         0.848   0.875   0.598   1.022   1.061   0.628   0.895   0.936   0.439
102   N        -1.201  -1.244  -1.131  -1.210  -1.261  -1.126  -1.007  -1.033  -0.872
103   A        -1.201  -1.149  -1.131  -1.237  -1.174  -1.125  -1.007  -0.968  -0.873
104   T        -0.710  -0.692  -0.789  -0.507  -0.479  -0.648  -0.629  -0.609  -0.686
105   L         0.764   0.688   0.568   0.775   0.699   0.555   0.740   0.638   0.378
106   T        -1.789  -1.808  -1.631  -1.624  -1.650  -1.438  -1.243  -1.252  -1.053
107   P         0.764   0.664   0.536   0.889   0.764   0.515   0.740   0.599   0.313
108   R        -1.075  -1.075  -1.098  -0.739  -0.750  -0.771  -0.866  -0.879  -0.840
109   G         1.030   1.051   0.703   1.183   1.218   0.798   1.166   1.200   0.618
110   S        -0.522  -0.488  -0.512  -0.551  -0.528  -0.566  -0.582  -0.563  -0.570
111   H        -0.968  -0.999  -0.884  -0.920  -0.962  -0.782  -0.913  -0.937  -0.782
112   D        -0.250  -0.155  -0.371  -0.239  -0.100  -0.414  -0.299  -0.172  -0.415
113   D        -1.085  -1.104  -0.917  -1.164  -1.154  -0.933  -1.007  -1.016  -0.810
114   V         1.030   0.939   0.683   1.175   1.061   0.698   1.166   1.026   0.584
115   V        -0.968  -0.977  -0.881  -0.978  -0.992  -0.837  -0.913  -0.922  -0.778
116   Q        -0.063  -0.008  -0.069  -0.151  -0.082  -0.161  -0.251  -0.185  -0.272
117   S         1.972   1.995   2.190   1.943   1.971   2.285   2.252   2.294   2.641
118   V         0.054   0.131   0.001  -0.063   0.059  -0.100  -0.157  -0.041  -0.190
119   K         0.196   0.193   0.311  -0.093  -0.113   0.017  -0.157  -0.171  -0.057
120   N         0.242   0.247   0.318   0.141   0.131   0.194  -0.110  -0.120  -0.054
121   S        -0.968  -0.922  -0.868  -0.932  -0.884  -0.809  -0.913  -0.875  -0.768
122   V        -0.593  -0.638  -0.502  -0.851  -0.898  -0.688  -0.724  -0.759  -0.580
123   S        -1.272  -1.214  -1.148  -1.343  -1.275  -1.150  -1.054  -1.011  -0.885
124   A        -2.164  -2.109  -2.002  -1.769  -1.708  -1.549  -1.338  -1.307  -1.148
125   I         0.112   0.129   0.280  -0.311  -0.288  -0.085  -0.299  -0.279  -0.108
126   G        -0.888  -0.898  -0.847  -0.818  -0.831  -0.777  -0.818  -0.820  -0.741
127   G         0.324   0.250   0.028   0.432   0.312  -0.018   0.315   0.188  -0.131
128   Y        -1.789  -1.813  -1.639  -1.503  -1.542  -1.303  -1.243  -1.254  -1.057
129   -         0.209   0.210   0.004   0.312   0.313  -0.005   0.182   0.182  -0.145
130   -        -0.809  -0.923  -0.870  -0.690  -0.862  -0.813  -0.705  -0.830  -0.757
131   I        -0.193  -0.154  -0.121  -0.458  -0.383  -0.360  -0.440  -0.384  -0.346
132   D         0.324   0.321   0.071   0.538   0.532   0.163   0.315   0.308  -0.057
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   I         0.462   0.454   0.449   0.231   0.207   0.223   0.174   0.155   0.139
137   F         1.217   1.152   1.120   1.333   1.241   1.166   1.213   1.083   0.896
138   E         0.887   0.886   1.021   0.696   0.685   0.874   0.552   0.535   0.671
139   V        -0.593  -0.573  -0.530  -0.529  -0.499  -0.417  -0.724  -0.706  -0.605
140   A         1.972   1.995   2.190   1.938   1.966   2.280   2.252   2.294   2.641
141   R         1.495   1.385   1.339   1.728   1.596   1.550   1.685   1.508   1.365
142   I        -0.559  -0.551  -0.517  -0.770  -0.777  -0.715  -0.677  -0.675  -0.590
143   D         1.972   1.995   2.190   2.040   2.072   2.384   2.252   2.294   2.641
144   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   G         0.087   0.163  -0.033   0.223   0.332   0.022  -0.015   0.093  -0.213
153   E        -1.039  -1.043  -0.914  -1.150  -1.159  -0.985  -0.960  -0.966  -0.805
154   V         1.217   1.131   1.129   1.242   1.110   1.071   1.213   1.041   0.917
155   Y        -0.063  -0.019  -0.080   0.007   0.070  -0.022  -0.251  -0.192  -0.279
156   P        -0.334  -0.291  -0.425  -0.337  -0.282  -0.402  -0.440  -0.389  -0.481
157   Y        -0.509  -0.475  -0.738  -0.357  -0.314  -0.697  -0.393  -0.352  -0.623
158   E         0.324   0.391   0.113   0.428   0.526   0.159   0.315   0.425   0.010
159   S         1.217   1.266   1.199   1.293   1.362   1.231   1.213   1.298   1.071
160   F        -0.780  -0.763  -0.628  -0.835  -0.802  -0.693  -0.866  -0.848  -0.691
161   E        -1.226  -1.229  -1.159  -1.238  -1.263  -1.185  -1.007  -1.017  -0.892
162   A        -0.451  -0.479  -0.481  -0.386  -0.405  -0.401  -0.535  -0.559  -0.545
163   L        -0.147  -0.132  -0.105  -0.391  -0.378  -0.309  -0.393  -0.381  -0.329
164   A        -0.817  -0.778  -0.814  -0.897  -0.853  -0.904  -0.771  -0.737  -0.721
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   E         0.157   0.275   0.033   0.122   0.265  -0.063   0.032   0.173  -0.134
167   M        -0.334  -0.305  -0.421  -0.127  -0.095  -0.198  -0.440  -0.414  -0.484
168   I         0.582   0.631   0.494   0.558   0.623   0.429   0.410   0.483   0.226
169   S        -0.063  -0.042  -0.091  -0.092  -0.059  -0.166  -0.251  -0.224  -0.300
170   E        -0.593  -0.574  -0.521  -0.825  -0.806  -0.701  -0.724  -0.709  -0.598
171   G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
172   V        -0.817  -0.792  -0.805  -0.909  -0.891  -0.928  -0.771  -0.763  -0.711
173   I         1.030   1.075   0.705   1.140   1.194   0.717   1.166   1.235   0.622
174   G        -0.134  -0.143  -0.124  -0.179  -0.191  -0.210  -0.299  -0.323  -0.331
175   G         0.196   0.198   0.323   0.026   0.031   0.177  -0.157  -0.161  -0.035
176   I         0.764   0.833   0.622   0.782   0.880   0.561   0.740   0.861   0.476
177   S         0.393   0.393   0.425   0.117   0.114   0.181   0.032   0.028   0.089
178   L         1.972   1.995   2.190   1.837   1.868   2.177   2.252   2.294   2.641
179   S         1.495   1.385   1.339   1.572   1.452   1.440   1.685   1.508   1.365
180   E         1.972   1.995   2.190   1.914   1.941   2.255   2.252   2.294   2.641
181   V         1.030   0.968   0.691   1.194   1.117   0.759   1.166   1.066   0.598
182   N        -0.451  -0.418  -0.489  -0.486  -0.450  -0.540  -0.535  -0.506  -0.552
183   E        -0.101  -0.180  -0.368   0.001  -0.103  -0.437  -0.063  -0.154  -0.392
184   E         0.087   0.100  -0.039   0.088   0.098  -0.130  -0.015  -0.004  -0.220
185   Q        -0.559  -0.602  -0.523  -0.565  -0.627  -0.524  -0.677  -0.712  -0.594
186   I         1.972   1.995   2.190   1.933   1.959   2.274   2.252   2.294   2.641
187   R        -1.156  -1.155  -1.127  -0.950  -0.961  -0.885  -0.960  -0.959  -0.864
188   A         0.050   0.062   0.256  -0.292  -0.280  -0.008  -0.393  -0.383  -0.147
189   I         0.345   0.372   0.359   0.164   0.202   0.112   0.079   0.119   0.025
190   H        -0.700  -0.660  -0.582  -0.680  -0.613  -0.610  -0.771  -0.728  -0.641
191   K        -0.063  -0.084  -0.093  -0.219  -0.254  -0.303  -0.251  -0.279  -0.304
192   D        -0.710  -0.692  -0.570  -0.945  -0.915  -0.778  -0.818  -0.795  -0.638
193   W        -1.156  -1.139  -1.134  -0.979  -0.965  -0.919  -0.960  -0.946  -0.870
194   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   F        -0.559  -0.599  -0.528  -0.550  -0.592  -0.478  -0.677  -0.710  -0.597
197   L         0.462   0.516   0.462   0.207   0.284   0.210   0.174   0.252   0.169
198   T        -0.264  -0.244  -0.171  -0.458  -0.434  -0.369  -0.488  -0.464  -0.397
199   C         0.758   0.773   0.971   0.588   0.596   0.889   0.268   0.283   0.553
200   V         1.495   1.385   1.339   1.581   1.450   1.402   1.685   1.508   1.365
201   E         1.972   1.995   2.190   1.914   1.941   2.255   2.252   2.294   2.641
202   V         0.136   0.160  -0.252   0.408   0.437  -0.143   0.268   0.299  -0.236
203   E         1.495   1.385   1.339   1.543   1.422   1.409   1.685   1.508   1.365
204   L         0.157   0.168   0.012   0.104   0.113  -0.080   0.032   0.037  -0.156
205   S         1.972   1.995   2.190   1.943   1.971   2.285   2.252   2.294   2.641
206   L         0.582   0.534   0.470   0.480   0.407   0.328   0.410   0.315   0.179
207   F         0.345   0.277   0.341   0.358   0.239   0.278   0.079  -0.034  -0.006
208   S        -0.817  -0.885  -0.830  -0.732  -0.819  -0.699  -0.771  -0.830  -0.733
209   N        -0.968  -0.941  -0.887  -0.816  -0.784  -0.698  -0.913  -0.893  -0.782
210   D         0.004   0.027  -0.019  -0.091  -0.081  -0.058  -0.251  -0.234  -0.233
211   I         0.324   0.349   0.052   0.423   0.452   0.020   0.315   0.350  -0.094
212   L         0.157   0.127   0.002   0.011  -0.036  -0.216   0.032  -0.011  -0.169
213   H        -1.343  -1.358  -1.183  -1.267  -1.277  -1.058  -1.102  -1.108  -0.910
214   N         1.495   1.502   1.354   1.703   1.717   1.564   1.685   1.699   1.395
215   G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
216   I         0.393   0.432   0.447   0.151   0.217   0.266   0.032   0.097   0.123
217   A        -0.334  -0.355  -0.428  -0.465  -0.511  -0.569  -0.440  -0.466  -0.493
218   K        -0.254  -0.204  -0.144  -0.560  -0.500  -0.399  -0.535  -0.482  -0.381
219   T        -0.817  -0.850  -0.823  -0.886  -0.950  -0.933  -0.771  -0.799  -0.727
220   C         1.495   1.502   1.354   1.836   1.847   1.670   1.685   1.699   1.395
221   A        -1.039  -1.012  -1.074  -0.938  -0.905  -0.934  -0.866  -0.849  -0.823
222   E        -0.254  -0.230  -0.155  -0.523  -0.509  -0.351  -0.535  -0.523  -0.396
223   L        -0.710  -0.688  -0.789  -0.561  -0.534  -0.623  -0.629  -0.607  -0.688
224   G        -0.593  -0.589  -0.518  -0.718  -0.708  -0.590  -0.724  -0.720  -0.591
225   L         0.462   0.501   0.452   0.235   0.284   0.234   0.174   0.226   0.141
226   S         1.030   1.090   0.707   1.242   1.315   0.820   1.166   1.256   0.625
227   I         0.462   0.438   0.439   0.207   0.144   0.138   0.174   0.121   0.114
228   I         0.324   0.232   0.031   0.401   0.255  -0.069   0.315   0.171  -0.127
229   C         1.022   1.063   1.117   0.961   1.017   1.090   0.835   0.908   0.890
230   Y         1.495   1.385   1.339   1.787   1.667   1.653   1.685   1.508   1.365
231   S         1.217   1.250   1.166   1.187   1.230   1.063   1.213   1.269   0.998
232   P         1.972   1.995   2.190   2.034   2.064   2.378   2.252   2.294   2.641
233   L         0.511   0.605   0.483   0.365   0.498   0.266   0.363   0.508   0.236
234   G         0.582   0.528   0.495   0.597   0.547   0.482   0.410   0.358   0.236
235   R        -0.321  -0.358  -0.440  -0.040  -0.101  -0.239  -0.346  -0.400  -0.489
236   G         1.972   1.995   2.190   1.948   1.986   2.290   2.252   2.294   2.641
237   L        -0.334  -0.331  -0.413  -0.478  -0.470  -0.531  -0.440  -0.431  -0.478
238   L         1.972   1.995   2.190   1.837   1.868   2.177   2.252   2.294   2.641
239   T         1.972   1.995   2.190   2.048   2.079   2.392   2.252   2.294   2.641
240   G         1.217   1.222   1.192   1.211   1.224   1.152   1.213   1.217   1.055
241   Q        -0.334  -0.337  -0.444  -0.110  -0.121  -0.239  -0.440  -0.449  -0.507
242   L        -0.817  -0.841  -0.815  -0.904  -0.947  -0.921  -0.771  -0.798  -0.720
243   K        -0.063  -0.088  -0.094  -0.178  -0.235  -0.257  -0.251  -0.303  -0.306
244   S        -0.593  -0.588  -0.525  -0.768  -0.760  -0.660  -0.724  -0.717  -0.598
245   N        -1.450  -1.440  -1.552  -0.971  -0.947  -1.198  -0.960  -0.958  -0.992
246   A        -0.710  -0.686  -0.556  -0.906  -0.873  -0.679  -0.818  -0.796  -0.627
247   D         1.972   1.995   2.190   2.040   2.072   2.384   2.252   2.294   2.641
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   I         0.393   0.412   0.442   0.045   0.094   0.143   0.032   0.077   0.117
254   P        -0.509  -0.511  -0.716  -0.285  -0.280  -0.638  -0.393  -0.387  -0.597
255   E        -1.156  -1.195  -1.108  -1.110  -1.154  -1.031  -0.960  -0.987  -0.853
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   G        -0.250  -0.281  -0.403  -0.182  -0.199  -0.384  -0.299  -0.313  -0.446
261   D         0.582   0.547   0.500   0.616   0.597   0.477   0.410   0.393   0.246
262   F         0.136   0.025  -0.293   0.526   0.393  -0.036   0.268   0.120  -0.289
263   R         0.582   0.547   0.500   0.669   0.670   0.546   0.410   0.393   0.246
264   K        -1.039  -1.047  -1.073  -0.878  -0.879  -0.905  -0.866  -0.875  -0.822
265   S        -1.601  -1.579  -1.568  -0.981  -0.950  -0.971  -1.102  -1.089  -1.009
266   L        -0.321  -0.376  -0.449  -0.263  -0.327  -0.411  -0.346  -0.406  -0.498
267   K        -0.593  -0.658  -0.548  -0.741  -0.825  -0.670  -0.724  -0.773  -0.620
268   R        -0.334  -0.396  -0.424  -0.231  -0.308  -0.316  -0.440  -0.505  -0.488
269   F         1.030   0.898   0.675   1.285   1.135   0.858   1.166   0.968   0.571
270   S        -0.513  -0.557  -0.492  -0.455  -0.503  -0.381  -0.629  -0.669  -0.564
271   D        -0.147  -0.215  -0.130  -0.253  -0.340  -0.254  -0.393  -0.458  -0.355
272   E         0.157   0.128   0.005   0.119   0.083  -0.121   0.032   0.003  -0.179
273   S        -0.710  -0.704  -0.583  -0.827  -0.821  -0.654  -0.818  -0.817  -0.652
274   L         0.887   0.911   1.026   0.683   0.722   0.824   0.552   0.589   0.683
275   K        -1.460  -1.481  -1.362  -1.381  -1.426  -1.222  -1.102  -1.116  -0.951
276   K        -1.039  -1.093  -1.081  -0.826  -0.894  -0.893  -0.866  -0.908  -0.829
277   N         1.495   1.385   1.339   1.703   1.579   1.541   1.685   1.508   1.365
278   L        -0.451  -0.399  -0.444  -0.557  -0.473  -0.525  -0.535  -0.466  -0.497
279   T        -1.226  -1.195  -1.155  -1.090  -1.052  -1.003  -1.007  -0.981  -0.886
280   L        -0.321  -0.350  -0.411  -0.354  -0.365  -0.478  -0.346  -0.365  -0.442
281   V         0.582   0.528   0.495   0.493   0.445   0.322   0.410   0.358   0.236
282   R        -1.272  -1.272  -1.159  -1.171  -1.166  -1.017  -1.054  -1.054  -0.894
283   F        -0.897  -0.898  -0.866  -0.933  -0.943  -0.864  -0.866  -0.866  -0.768
284   L         0.242   0.299   0.383  -0.121  -0.028   0.060  -0.110  -0.019   0.054
285   Q        -1.005  -0.996  -1.061  -0.833  -0.851  -0.848  -0.818  -0.824  -0.813
286   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   K         0.192   0.251   0.355  -0.128  -0.067   0.106  -0.204  -0.139  -0.006
292   R        -0.513  -0.503  -0.508  -0.579  -0.572  -0.531  -0.629  -0.618  -0.574
293   P         0.582   0.629   0.511   0.519   0.585   0.408   0.410   0.484   0.268
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   Q        -1.306  -1.347  -1.175  -1.305  -1.371  -1.131  -1.074  -1.101  -0.905
296   N        -0.402  -0.394  -0.696  -0.170  -0.161  -0.621  -0.243  -0.233  -0.573
297   N        -0.897  -0.929  -1.038  -0.651  -0.678  -0.836  -0.677  -0.701  -0.774
298   S        -0.639  -0.688  -0.788  -0.516  -0.578  -0.723  -0.582  -0.636  -0.689
299   I        -1.085  -1.066  -0.928  -0.942  -0.918  -0.723  -1.007  -0.993  -0.818
300   T         0.582   0.534   0.475   0.606   0.520   0.406   0.410   0.321   0.188
301   L         0.345   0.438   0.431   0.163   0.289   0.269   0.079   0.217   0.141
302   A         0.192   0.208   0.343  -0.100  -0.079   0.102  -0.204  -0.179  -0.018
303   Q         0.345   0.337   0.385   0.372   0.346   0.347   0.079   0.058   0.067
304   L        -0.193  -0.159  -0.106  -0.429  -0.366  -0.275  -0.440  -0.387  -0.321
305   A         1.217   1.276   1.153   1.183   1.263   1.036   1.213   1.317   0.970
306   L         0.800   0.821   0.987   0.349   0.374   0.599   0.363   0.390   0.591
307   G        -0.710  -0.641  -0.566  -0.928  -0.838  -0.745  -0.818  -0.759  -0.636
308   W         1.022   1.025   1.100   1.223   1.221   1.289   0.835   0.830   0.851
309   V         0.242   0.267   0.345  -0.005   0.025   0.116  -0.110  -0.077  -0.011
310   K        -0.897  -0.838  -0.828  -0.987  -0.948  -0.876  -0.866  -0.826  -0.740
311   H        -0.888  -0.896  -0.860  -0.821  -0.862  -0.788  -0.818  -0.834  -0.758
312   W        -0.675  -0.706  -0.586  -0.706  -0.753  -0.598  -0.781  -0.807  -0.653
313   N         1.092   1.158   1.139   1.043   1.136   1.081   0.975   1.095   0.939
314   K        -0.977  -0.989  -0.878  -1.020  -1.041  -0.887  -0.902  -0.912  -0.771
315   V        -1.622  -1.612  -1.453  -1.474  -1.461  -1.289  -1.197  -1.191  -1.008
316   P        -0.851  -0.904  -0.824  -0.841  -0.911  -0.793  -0.818  -0.858  -0.731
317   E        -0.063  -0.024  -0.093  -0.148  -0.089  -0.229  -0.251  -0.207  -0.303
318   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   G        -1.531  -1.558  -1.399  -1.226  -1.248  -1.036  -1.149  -1.166  -0.976
325   A        -0.710  -0.681  -0.583  -0.879  -0.835  -0.711  -0.818  -0.791  -0.652
326   K        -0.817  -0.770  -0.834  -0.790  -0.749  -0.805  -0.771  -0.751  -0.739
327   F         0.345   0.427   0.403   0.201   0.322   0.242   0.079   0.203   0.101
328   I         1.022   0.968   1.046   0.836   0.719   0.762   0.835   0.711   0.728
329   P         1.972   1.995   2.190   2.034   2.064   2.378   2.252   2.294   2.641
330   I         1.972   1.995   2.190   1.933   1.959   2.274   2.252   2.294   2.641
331   P         1.972   1.995   2.190   2.034   2.064   2.378   2.252   2.294   2.641
332   S         0.758   0.785   0.977   0.360   0.404   0.678   0.268   0.310   0.568
333   G        -0.147  -0.116  -0.098  -0.356  -0.313  -0.283  -0.393  -0.362  -0.320
334   S         0.758   0.777   0.970   0.440   0.461   0.741   0.268   0.291   0.552
335   S         0.758   0.774   0.970   0.440   0.452   0.741   0.268   0.284   0.551
336   I        -0.817  -0.878  -0.825  -0.840  -0.917  -0.855  -0.771  -0.826  -0.727
337   S        -1.226  -1.203  -1.148  -1.249  -1.229  -1.150  -1.007  -0.993  -0.884
338   K         0.764   0.683   0.551   0.961   0.858   0.596   0.740   0.631   0.346
339   V        -0.101  -0.090  -0.380   0.044   0.014  -0.432  -0.063  -0.082  -0.417
340   N        -1.156  -1.103  -1.095  -1.124  -1.046  -1.040  -0.960  -0.909  -0.843
341   E         0.054  -0.012  -0.033  -0.126  -0.200  -0.248  -0.157  -0.215  -0.237
342   N         1.495   1.385   1.339   1.694   1.566   1.517   1.685   1.508   1.365
343   F        -0.083  -0.096  -0.101  -0.147  -0.159  -0.133  -0.302  -0.319  -0.313
344   D        -0.706  -0.642  -0.573  -0.840  -0.741  -0.679  -0.803  -0.738  -0.638
345   E        -0.570  -0.589  -0.537  -0.759  -0.803  -0.699  -0.686  -0.710  -0.608
346   Q        -1.156  -1.186  -1.135  -1.245  -1.286  -1.210  -0.960  -0.983  -0.872
347   K        -0.859  -0.890  -0.852  -0.847  -0.912  -0.872  -0.781  -0.818  -0.746
348   T        -1.026  -1.007  -0.900  -1.163  -1.141  -0.980  -0.963  -0.947  -0.795
349   K        -1.226  -1.235  -1.136  -1.216  -1.224  -1.089  -1.007  -1.010  -0.872
350   L         1.495   1.535   1.358   1.439   1.489   1.289   1.685   1.750   1.403
351   T         0.370   0.296   0.419   0.153   0.076   0.270  -0.015  -0.090   0.076
352   D        -0.509  -0.543  -0.739  -0.258  -0.301  -0.653  -0.393  -0.429  -0.630
353   Q        -0.321  -0.391  -0.448  -0.210  -0.296  -0.370  -0.346  -0.423  -0.495
354   E        -0.254  -0.264  -0.154  -0.405  -0.416  -0.235  -0.535  -0.547  -0.391
355   F         0.192   0.210   0.331  -0.089  -0.063   0.127  -0.204  -0.186  -0.037
356   N        -0.851  -0.802  -0.802  -0.935  -0.868  -0.841  -0.818  -0.773  -0.714
357   A        -0.334  -0.315  -0.419  -0.468  -0.439  -0.570  -0.440  -0.415  -0.480
358   I         0.087   0.101  -0.020   0.048   0.050  -0.182  -0.015  -0.011  -0.194
359   N        -0.817  -0.847  -0.812  -0.717  -0.740  -0.703  -0.771  -0.787  -0.708
360   K        -0.700  -0.771  -0.743  -0.763  -0.857  -0.801  -0.677  -0.737  -0.656
361   Y        -1.014  -1.041  -0.903  -0.967  -0.984  -0.784  -0.960  -0.976  -0.798
362   L        -0.101  -0.090  -0.367  -0.025  -0.014  -0.396  -0.063  -0.055  -0.398
363   T        -1.601  -1.563  -1.566  -1.399  -1.364  -1.376  -1.102  -1.076  -1.008
364   T        -0.334  -0.303  -0.417  -0.430  -0.399  -0.517  -0.440  -0.412  -0.483
365   F        -0.134  -0.151  -0.172   0.005  -0.036  -0.078  -0.299  -0.332  -0.394
366   H        -1.718  -1.714  -1.602  -1.606  -1.640  -1.455  -1.196  -1.193  -1.035
367   T        -0.147  -0.118  -0.113  -0.299  -0.278  -0.247  -0.393  -0.375  -0.341
368   V        -1.263  -1.250  -1.324  -1.048  -1.047  -1.198  -0.913  -0.906  -0.915
369   G         1.495   1.385   1.339   1.560   1.441   1.395   1.685   1.508   1.365
370   D        -0.710  -0.695  -0.575  -0.981  -0.963  -0.772  -0.818  -0.809  -0.646
371   R         1.217   1.147   1.116   1.368   1.255   1.144   1.213   1.074   0.888
372   Y         1.030   0.898   0.675   1.376   1.219   0.916   1.166   0.968   0.571
373   E        -0.513  -0.504  -0.511  -0.504  -0.478  -0.451  -0.629  -0.613  -0.577
374   M        -1.531  -1.544  -1.402  -1.344  -1.365  -1.169  -1.149  -1.156  -0.975
375   A        -1.789  -1.804  -1.635  -1.499  -1.547  -1.312  -1.243  -1.249  -1.054
376   -        -0.977  -1.007  -0.900  -1.144  -1.184  -1.035  -0.902  -0.933  -0.791
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -0.656  -0.661  -0.559  -0.807  -0.833  -0.689  -0.742  -0.759  -0.622
382   -        -1.076  -1.074  -0.916  -1.171  -1.159  -0.957  -0.991  -0.992  -0.806
383   -        -0.675  -0.707  -0.570  -0.837  -0.885  -0.718  -0.781  -0.808  -0.639
384   -        -0.859  -0.908  -0.850  -0.890  -0.968  -0.877  -0.781  -0.839  -0.745
385   -        -1.010  -1.061  -0.916  -0.957  -1.013  -0.817  -0.941  -0.979  -0.805
386   -        -2.024  -2.005  -1.846  -1.669  -1.600  -1.431  -1.311  -1.301  -1.115
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06494
Output conservation file - output/Q06494
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
