1     M         1.875   1.882   1.934   2.168   2.175   2.262   2.081   2.091   2.176
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    N        -0.319  -0.321  -0.307  -0.351  -0.340  -0.323  -0.439  -0.441  -0.419
11    Q        -1.051  -1.039  -0.993  -0.956  -0.936  -0.865  -0.943  -0.929  -0.862
12    I         0.688   0.646   0.614   0.641   0.569   0.506   0.569   0.493   0.419
13    W        -1.051  -1.039  -0.993  -0.710  -0.698  -0.619  -0.943  -0.929  -0.862
14    S        -1.051  -1.039  -0.993  -1.020  -0.985  -0.929  -0.943  -0.929  -0.862
15    T         0.532   0.569   0.547   0.465   0.534   0.476   0.289   0.356   0.296
16    G        -0.444  -0.431  -0.386  -0.562  -0.560  -0.470  -0.607  -0.590  -0.525
17    P         1.875   1.882   1.934   2.029   2.039   2.122   2.081   2.091   2.176
18    P        -0.444  -0.431  -0.386  -0.550  -0.565  -0.458  -0.607  -0.590  -0.525
19    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    F        -0.444  -0.432  -0.386  -0.490  -0.482  -0.399  -0.607  -0.591  -0.525
23    N         0.532   0.489   0.515   0.034  -0.034  -0.009   0.289   0.208   0.235
24    S         0.688   0.664   0.618   0.629   0.590   0.468   0.569   0.525   0.427
25    E        -1.051  -1.044  -0.993  -1.255  -1.227  -1.164  -0.943  -0.934  -0.862
26    W        -0.319  -0.278  -0.313  -0.113  -0.048  -0.116  -0.439  -0.381  -0.427
27    K        -1.051  -1.044  -0.993  -1.020  -1.015  -0.929  -0.943  -0.934  -0.862
28    E         0.688   0.724   0.648   0.603   0.667   0.505   0.569   0.630   0.481
29    -        -0.444  -0.429  -0.386  -0.497  -0.479  -0.406  -0.607  -0.587  -0.525
30    -         0.532   0.580   0.549   0.467   0.536   0.497   0.289   0.375   0.299
31    -        -0.444  -0.429  -0.386  -0.764  -0.725  -0.673  -0.607  -0.587  -0.525
32    -        -0.444  -0.429  -0.386  -0.459  -0.443  -0.367  -0.607  -0.587  -0.525
33    N        -0.351  -0.337  -0.336  -0.491  -0.471  -0.469  -0.499  -0.482  -0.464
34    K        -0.937  -0.953  -0.956  -1.034  -1.051  -1.084  -0.822  -0.839  -0.824
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    R        -0.937  -0.945  -0.931  -1.018  -1.042  -1.024  -0.822  -0.830  -0.798
49    N        -0.937  -0.904  -0.921  -1.110  -1.061  -1.070  -0.822  -0.783  -0.787
50    D        -0.131  -0.163  -0.227   0.051  -0.007  -0.090  -0.177  -0.223  -0.309
51    R        -0.937  -0.953  -0.956  -0.854  -0.886  -0.901  -0.822  -0.839  -0.824
52    T        -0.937  -0.953  -0.956  -0.988  -1.008  -1.045  -0.822  -0.839  -0.824
53    I        -0.937  -0.953  -0.956  -0.996  -1.023  -1.049  -0.822  -0.839  -0.824
54    E        -0.937  -0.953  -0.956  -0.789  -0.824  -0.815  -0.822  -0.839  -0.824
55    D        -0.131  -0.110  -0.234  -0.144  -0.106  -0.356  -0.177  -0.147  -0.318
56    S        -0.131  -0.174  -0.239  -0.372  -0.431  -0.533  -0.177  -0.237  -0.325
57    L        -0.937  -0.953  -0.956  -1.067  -1.091  -1.125  -0.822  -0.839  -0.824
58    R        -1.522  -1.514  -1.464  -1.348  -1.351  -1.257  -1.145  -1.135  -1.065
59    E        -0.351  -0.378  -0.350  -0.594  -0.627  -0.565  -0.499  -0.527  -0.481
60    L         0.455   0.476   0.505  -0.012   0.033   0.068   0.146   0.183   0.217
61    D        -1.522  -1.514  -1.464  -1.191  -1.194  -1.100  -1.145  -1.135  -1.065
62    G         1.875   1.882   1.934   2.030   2.032   2.123   2.081   2.091   2.176
63    L        -0.351  -0.378  -0.350  -0.489  -0.521  -0.488  -0.499  -0.527  -0.481
64    I        -0.937  -0.945  -0.931  -0.854  -0.857  -0.840  -0.822  -0.830  -0.798
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    H        -0.319  -0.369  -0.343  -0.058  -0.145  -0.106  -0.439  -0.507  -0.469
67    S        -0.319  -0.321  -0.307  -0.480  -0.487  -0.443  -0.439  -0.441  -0.419
68    L        -1.522  -1.514  -1.464  -1.609  -1.590  -1.518  -1.145  -1.135  -1.065
69    E        -1.051  -1.044  -0.993  -1.082  -1.073  -0.991  -0.943  -0.934  -0.862
70    R        -0.319  -0.278  -0.313  -0.138  -0.085  -0.120  -0.439  -0.381  -0.427
71    T         0.688   0.664   0.618   0.365   0.344   0.258   0.569   0.525   0.427
72    H        -1.051  -1.044  -0.993  -0.948  -0.932  -0.857  -0.943  -0.934  -0.862
73    I        -1.051  -1.044  -0.993  -1.179  -1.160  -1.088  -0.943  -0.934  -0.862
74    E        -0.937  -0.939  -0.954  -0.825  -0.823  -0.829  -0.822  -0.823  -0.823
75    V        -0.937  -0.953  -0.956  -0.707  -0.747  -0.727  -0.822  -0.839  -0.824
76    Q        -0.937  -0.939  -0.954  -0.682  -0.696  -0.724  -0.822  -0.823  -0.823
77    T        -1.522  -1.514  -1.464  -1.158  -1.157  -1.067  -1.145  -1.135  -1.065
78    N        -0.937  -0.939  -0.954  -0.895  -0.892  -0.934  -0.822  -0.823  -0.823
79    P         1.875   1.882   1.934   2.050   2.056   2.143   2.081   2.091   2.176
80    K        -0.351  -0.337  -0.336  -0.410  -0.394  -0.380  -0.499  -0.482  -0.464
81    L        -0.351  -0.378  -0.350  -0.649  -0.670  -0.617  -0.499  -0.527  -0.481
82    K        -1.522  -1.514  -1.464  -1.453  -1.433  -1.362  -1.145  -1.135  -1.065
83    N        -0.351  -0.337  -0.336  -0.639  -0.613  -0.571  -0.499  -0.482  -0.464
84    D        -0.937  -0.913  -0.927  -0.782  -0.750  -0.767  -0.822  -0.794  -0.794
85    V        -0.937  -0.952  -0.923  -0.761  -0.795  -0.738  -0.822  -0.838  -0.789
86    T        -0.351  -0.343  -0.333  -0.382  -0.373  -0.341  -0.499  -0.487  -0.460
87    A        -0.131  -0.085  -0.229  -0.318  -0.249  -0.449  -0.177  -0.113  -0.311
88    L        -0.937  -0.904  -0.921  -0.807  -0.751  -0.777  -0.822  -0.783  -0.787
89    N        -0.937  -0.945  -0.931  -1.157  -1.159  -1.133  -0.822  -0.830  -0.798
90    D        -0.937  -0.945  -0.931  -0.829  -0.847  -0.844  -0.822  -0.830  -0.798
91    I        -0.937  -0.940  -0.923  -0.970  -0.995  -0.963  -0.822  -0.824  -0.789
92    N        -0.131  -0.174  -0.239  -0.104  -0.166  -0.264  -0.177  -0.237  -0.325
93    K        -1.522  -1.514  -1.464  -1.248  -1.237  -1.157  -1.145  -1.135  -1.065
94    K        -1.522  -1.514  -1.464  -1.488  -1.498  -1.398  -1.145  -1.135  -1.065
95    E        -0.937  -0.939  -0.954  -0.942  -0.959  -0.975  -0.822  -0.823  -0.823
96    N        -0.444  -0.430  -0.386  -0.502  -0.467  -0.410  -0.607  -0.588  -0.525
97    K        -0.444  -0.430  -0.386  -0.713  -0.671  -0.621  -0.607  -0.588  -0.525
98    E        -0.319  -0.309  -0.308  -0.215  -0.201  -0.195  -0.439  -0.424  -0.420
99    E        -1.051  -1.046  -0.993  -1.008  -0.995  -0.917  -0.943  -0.936  -0.862
100   -         0.532   0.565   0.547   0.420   0.475   0.435   0.289   0.348   0.296
101   -         0.532   0.563   0.539   0.523   0.578   0.518   0.289   0.345   0.281
102   -         0.532   0.563   0.539   0.493   0.541   0.489   0.289   0.345   0.281
103   -         0.532   0.492   0.515   0.493   0.431   0.471   0.289   0.213   0.235
104   -        -0.444  -0.433  -0.386  -0.672  -0.615  -0.581  -0.607  -0.593  -0.525
105   -         1.875   1.882   1.934   1.914   1.923   2.008   2.081   2.091   2.176
106   -         0.532   0.492   0.515   0.796   0.730   0.763   0.289   0.213   0.235
107   -         0.532   0.492   0.515   0.145   0.091   0.120   0.289   0.213   0.235
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   I         0.532   0.569   0.547   0.494   0.563   0.502   0.289   0.356   0.296
122   T         1.875   1.882   1.934   1.866   1.872   1.960   2.081   2.091   2.176
123   H         1.875   1.882   1.934   2.145   2.159   2.238   2.081   2.091   2.176
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   E        -0.444  -0.431  -0.386  -0.496  -0.471  -0.404  -0.607  -0.590  -0.525
132   N         0.532   0.569   0.548   0.313   0.373   0.330   0.289   0.356   0.298
133   Y        -0.444  -0.431  -0.386  -0.322  -0.312  -0.230  -0.607  -0.590  -0.525
134   T         0.532   0.569   0.548   0.268   0.334   0.269   0.289   0.356   0.298
135   H        -0.444  -0.431  -0.386  -0.395  -0.389  -0.303  -0.607  -0.590  -0.525
136   Q        -0.444  -0.431  -0.386  -0.402  -0.381  -0.311  -0.607  -0.590  -0.525
137   I         0.532   0.485   0.514   0.355   0.262   0.305   0.289   0.200   0.233
138   N         0.532   0.485   0.514   0.410   0.335   0.386   0.289   0.200   0.233
139   S         0.532   0.485   0.514   0.120   0.025   0.074   0.289   0.200   0.233
140   I        -0.444  -0.431  -0.386  -0.527  -0.498  -0.435  -0.607  -0.590  -0.525
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   P        -0.319  -0.300  -0.307  -0.417  -0.416  -0.409  -0.439  -0.414  -0.419
144   L         0.412   0.418   0.470   0.136   0.143   0.228   0.065   0.073   0.150
145   T        -0.319  -0.369  -0.343  -0.402  -0.488  -0.457  -0.439  -0.507  -0.469
146   S        -0.319  -0.322  -0.313  -0.672  -0.684  -0.661  -0.439  -0.443  -0.427
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   S        -0.319  -0.322  -0.313  -0.494  -0.505  -0.464  -0.439  -0.443  -0.427
150   N         0.688   0.729   0.648   0.569   0.635   0.495   0.569   0.638   0.481
151   L        -0.319  -0.369  -0.343  -0.162  -0.218  -0.161  -0.439  -0.507  -0.469
152   N        -0.319  -0.245  -0.306  -0.502  -0.346  -0.506  -0.439  -0.335  -0.418
153   R        -0.444  -0.439  -0.386  -0.451  -0.444  -0.359  -0.607  -0.600  -0.525
154   H        -0.444  -0.439  -0.386  -0.634  -0.634  -0.543  -0.607  -0.600  -0.525
155   F         0.532   0.533   0.543   0.525   0.527   0.545   0.289   0.290   0.288
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -         0.532   0.479   0.515   0.375   0.246   0.282   0.289   0.189   0.235
162   S         0.688   0.671   0.620   0.365   0.354   0.261   0.569   0.537   0.430
163   F        -0.319  -0.313  -0.308  -0.250  -0.237  -0.222  -0.439  -0.430  -0.420
164   S        -0.937  -0.913  -0.927  -1.049  -1.017  -1.011  -0.822  -0.794  -0.794
165   R        -1.522  -1.514  -1.464  -1.418  -1.409  -1.327  -1.145  -1.135  -1.065
166   D        -0.937  -0.940  -0.923  -0.888  -0.892  -0.872  -0.822  -0.824  -0.789
167   Y        -1.522  -1.514  -1.464  -1.222  -1.200  -1.131  -1.145  -1.135  -1.065
168   N        -0.937  -0.904  -0.921  -0.779  -0.735  -0.752  -0.822  -0.783  -0.787
169   Q        -0.351  -0.336  -0.324  -0.524  -0.511  -0.477  -0.499  -0.481  -0.451
170   S        -0.937  -0.904  -0.921  -1.013  -0.944  -0.998  -0.822  -0.783  -0.787
171   D        -0.937  -0.898  -0.921  -1.095  -1.040  -1.054  -0.822  -0.777  -0.787
172   N         0.455   0.476   0.505   0.362   0.403   0.437   0.146   0.183   0.217
173   S        -1.522  -1.514  -1.464  -1.587  -1.560  -1.496  -1.145  -1.135  -1.065
174   N        -1.051  -1.039  -0.993  -1.023  -0.997  -0.931  -0.943  -0.929  -0.862
175   N         0.532   0.569   0.548   0.313   0.373   0.330   0.289   0.356   0.298
176   N         0.688   0.687   0.619   0.618   0.623   0.504   0.569   0.565   0.429
177   Y         0.688   0.692   0.609   0.864   0.867   0.739   0.569   0.575   0.411
178   Y        -1.051  -1.046  -0.993  -1.003  -0.991  -0.912  -0.943  -0.936  -0.862
179   R        -0.319  -0.321  -0.317  -0.253  -0.267  -0.249  -0.439  -0.440  -0.432
180   E        -1.051  -1.046  -0.993  -0.933  -0.922  -0.841  -0.943  -0.936  -0.862
181   Y        -1.051  -1.046  -0.993  -0.938  -0.933  -0.847  -0.943  -0.936  -0.862
182   L         0.412   0.418   0.470   0.298   0.306   0.391   0.065   0.073   0.150
183   -        -0.444  -0.433  -0.386  -0.575  -0.551  -0.484  -0.607  -0.593  -0.525
184   -         0.532   0.563   0.539   0.364   0.430   0.339   0.289   0.345   0.281
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   S        -0.319  -0.324  -0.343  -0.564  -0.572  -0.573  -0.439  -0.445  -0.469
189   K         0.412   0.418   0.470   0.214   0.223   0.307   0.065   0.073   0.150
190   P        -0.319  -0.324  -0.343  -0.362  -0.380  -0.443  -0.439  -0.445  -0.469
191   R        -1.051  -1.046  -0.993  -1.048  -1.040  -0.957  -0.943  -0.936  -0.862
192   Y         0.688   0.685   0.609   0.851   0.851   0.706   0.569   0.562   0.411
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   L        -1.522  -1.514  -1.464  -1.216  -1.213  -1.125  -1.145  -1.135  -1.065
206   Q         0.819   0.857   0.702   1.121   1.170   0.960   0.791   0.853   0.579
207   Q        -0.937  -0.952  -0.923  -0.751  -0.784  -0.745  -0.822  -0.838  -0.789
208   S        -1.522  -1.514  -1.464  -1.541  -1.513  -1.450  -1.145  -1.135  -1.065
209   T        -0.937  -0.939  -0.954  -0.754  -0.761  -0.800  -0.822  -0.823  -0.823
210   K        -0.131  -0.152  -0.240   0.122   0.089  -0.054  -0.177  -0.207  -0.326
211   E        -0.937  -0.898  -0.921  -1.095  -1.041  -1.054  -0.822  -0.777  -0.787
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   Q        -1.051  -1.046  -0.993  -0.992  -0.982  -0.901  -0.943  -0.936  -0.862
214   T        -0.319  -0.308  -0.307  -0.364  -0.347  -0.350  -0.439  -0.423  -0.419
215   F         0.688   0.711   0.620   0.679   0.720   0.555   0.569   0.608   0.430
216   N        -0.319  -0.304  -0.342  -0.292  -0.275  -0.343  -0.439  -0.418  -0.467
217   E        -0.937  -0.945  -0.931  -1.150  -1.159  -1.125  -0.822  -0.830  -0.798
218   I        -0.937  -0.913  -0.927  -0.795  -0.760  -0.775  -0.822  -0.794  -0.794
219   N        -1.522  -1.514  -1.464  -1.422  -1.410  -1.331  -1.145  -1.135  -1.065
220   K        -0.937  -0.939  -0.954  -0.802  -0.819  -0.851  -0.822  -0.823  -0.823
221   R        -0.937  -0.913  -0.927  -0.668  -0.638  -0.645  -0.822  -0.794  -0.794
222   K        -0.937  -0.953  -0.956  -0.881  -0.911  -0.904  -0.822  -0.839  -0.824
223   S         1.875   1.882   1.934   1.653   1.654   1.746   2.081   2.091   2.176
224   A        -0.444  -0.428  -0.386  -0.481  -0.457  -0.390  -0.607  -0.585  -0.525
225   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   L        -0.937  -0.939  -0.954  -0.815  -0.807  -0.832  -0.822  -0.823  -0.823
232   N        -0.937  -0.953  -0.956  -0.839  -0.862  -0.845  -0.822  -0.839  -0.824
233   I         0.455   0.450   0.483   0.332   0.315   0.362   0.146   0.134   0.174
234   P         0.819   0.840   0.709   1.044   1.070   0.877   0.791   0.825   0.591
235   E        -0.937  -0.953  -0.956  -0.756  -0.778  -0.777  -0.822  -0.839  -0.824
236   N        -0.937  -0.952  -0.923  -0.903  -0.919  -0.875  -0.822  -0.838  -0.789
237   S         0.819   0.840   0.709   0.614   0.649   0.470   0.791   0.825   0.591
238   R         0.455   0.443   0.480   0.319   0.288   0.340   0.146   0.122   0.170
239   F         1.875   1.882   1.934   1.880   1.896   1.973   2.081   2.091   2.176
240   F         1.875   1.882   1.934   1.880   1.896   1.973   2.081   2.091   2.176
241   V         1.875   1.882   1.934   1.961   1.965   2.055   2.081   2.091   2.176
242   I         1.875   1.882   1.934   1.896   1.908   1.989   2.081   2.091   2.176
243   K         1.875   1.882   1.934   1.855   1.866   1.948   2.081   2.091   2.176
244   S         1.875   1.882   1.934   1.588   1.605   1.681   2.081   2.091   2.176
245   S        -0.937  -0.939  -0.954  -0.866  -0.865  -0.940  -0.822  -0.823  -0.823
246   S         0.455   0.443   0.480  -0.043  -0.055  -0.002   0.146   0.122   0.170
247   L        -0.937  -0.953  -0.956  -0.850  -0.876  -0.871  -0.822  -0.839  -0.824
248   K        -1.522  -1.514  -1.464  -1.262  -1.249  -1.171  -1.145  -1.135  -1.065
249   H        -0.351  -0.378  -0.350  -0.268  -0.316  -0.275  -0.499  -0.527  -0.481
250   V         0.819   0.842   0.708   0.948   0.977   0.777   0.791   0.829   0.588
251   K        -0.131  -0.110  -0.234  -0.119  -0.085  -0.290  -0.177  -0.147  -0.318
252   R        -0.937  -0.939  -0.954  -0.779  -0.791  -0.825  -0.822  -0.823  -0.823
253   S         0.819   0.759   0.676   0.614   0.537   0.422   0.791   0.689   0.533
254   F        -0.131  -0.165  -0.228  -0.095  -0.143  -0.257  -0.177  -0.225  -0.309
255   Y        -0.937  -0.953  -0.956  -0.601  -0.630  -0.632  -0.822  -0.839  -0.824
256   N         0.819   0.829   0.699   0.867   0.883   0.714   0.791   0.807   0.573
257   G        -0.351  -0.329  -0.333  -0.686  -0.660  -0.644  -0.499  -0.473  -0.460
258   I         0.819   0.759   0.676   0.900   0.813   0.687   0.791   0.689   0.533
259   W         1.875   1.882   1.934   2.156   2.162   2.250   2.081   2.091   2.176
260   S        -0.131  -0.110  -0.234  -0.310  -0.275  -0.445  -0.177  -0.147  -0.318
261   S         1.875   1.882   1.934   1.588   1.605   1.681   2.081   2.091   2.176
262   T         1.875   1.882   1.934   1.921   1.933   2.014   2.081   2.091   2.176
263   H        -0.937  -0.953  -0.956  -0.674  -0.711  -0.732  -0.822  -0.839  -0.824
264   F        -0.351  -0.378  -0.350  -0.503  -0.532  -0.497  -0.499  -0.527  -0.481
265   G         1.875   1.882   1.934   2.030   2.032   2.123   2.081   2.091   2.176
266   N         1.875   1.882   1.934   1.813   1.826   1.907   2.081   2.091   2.176
267   K         0.455   0.475   0.496   0.319   0.355   0.375   0.146   0.182   0.199
268   R         0.819   0.842   0.708   0.950   0.981   0.775   0.791   0.829   0.588
269   L         1.875   1.882   1.934   1.863   1.881   1.957   2.081   2.091   2.176
270   S        -0.937  -0.953  -0.956  -1.157  -1.172  -1.160  -0.822  -0.839  -0.824
271   E        -0.937  -0.904  -0.921  -0.745  -0.701  -0.720  -0.822  -0.783  -0.787
272   A         0.819   0.759   0.676   1.028   0.932   0.807   0.791   0.689   0.533
273   Y         0.819   0.840   0.709   1.066   1.095   0.893   0.791   0.825   0.591
274   K        -0.937  -0.953  -0.956  -0.792  -0.807  -0.801  -0.822  -0.839  -0.824
275   K        -0.131  -0.152  -0.240  -0.142  -0.193  -0.361  -0.177  -0.207  -0.326
276   L         0.819   0.840   0.709   0.868   0.905   0.709   0.791   0.825   0.591
277   N        -1.522  -1.514  -1.464  -1.543  -1.520  -1.452  -1.145  -1.135  -1.065
278   S        -0.937  -0.945  -0.931  -0.856  -0.864  -0.866  -0.822  -0.830  -0.798
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   G        -0.131  -0.110  -0.234   0.096   0.119  -0.072  -0.177  -0.147  -0.318
286   A         0.455   0.466   0.502   0.469   0.478   0.541   0.146   0.165   0.211
287   K         1.875   1.882   1.934   1.855   1.866   1.948   2.081   2.091   2.176
288   V        -0.131  -0.152  -0.240  -0.058  -0.094  -0.235  -0.177  -0.207  -0.326
289   F         1.875   1.882   1.934   1.880   1.896   1.973   2.081   2.091   2.176
290   L         1.875   1.882   1.934   1.863   1.881   1.957   2.081   2.091   2.176
291   F         0.819   0.759   0.676   0.860   0.778   0.634   0.791   0.689   0.533
292   F         1.875   1.882   1.934   1.880   1.896   1.973   2.081   2.091   2.176
293   S         0.819   0.840   0.709   0.569   0.609   0.405   0.791   0.825   0.591
294   I         0.819   0.857   0.702   0.948   0.998   0.768   0.791   0.853   0.579
295   N         1.875   1.882   1.934   1.813   1.826   1.907   2.081   2.091   2.176
296   T        -1.522  -1.514  -1.464  -1.360  -1.355  -1.269  -1.145  -1.135  -1.065
297   S         1.875   1.882   1.934   1.588   1.605   1.681   2.081   2.091   2.176
298   G         1.875   1.882   1.934   2.030   2.032   2.123   2.081   2.091   2.176
299   R         0.455   0.443   0.480   0.319   0.288   0.340   0.146   0.122   0.170
300   F         1.875   1.882   1.934   1.880   1.896   1.973   2.081   2.091   2.176
301   C         1.875   1.882   1.934   2.199   2.211   2.293   2.081   2.091   2.176
302   G         1.875   1.882   1.934   2.030   2.032   2.123   2.081   2.091   2.176
303   V         0.455   0.443   0.480   0.332   0.301   0.357   0.146   0.122   0.170
304   A         0.819   0.840   0.709   1.035   1.059   0.872   0.791   0.825   0.591
305   E         1.875   1.882   1.934   1.933   1.938   2.026   2.081   2.091   2.176
306   M         1.875   1.882   1.934   2.168   2.175   2.262   2.081   2.091   2.176
307   V        -0.937  -0.939  -0.954  -0.896  -0.882  -0.920  -0.822  -0.823  -0.823
308   S         0.819   0.840   0.709   0.556   0.595   0.387   0.791   0.825   0.591
309   D        -0.131  -0.110  -0.234  -0.005   0.027  -0.173  -0.177  -0.147  -0.318
310   L         0.455   0.466   0.502   0.248   0.275   0.319   0.146   0.165   0.211
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   K        -0.937  -0.939  -0.954  -0.767  -0.776  -0.791  -0.822  -0.823  -0.823
313   M        -0.937  -0.939  -0.954  -0.807  -0.818  -0.822  -0.822  -0.823  -0.823
314   D        -0.351  -0.337  -0.336  -0.293  -0.274  -0.241  -0.499  -0.482  -0.464
315   L        -0.937  -0.953  -0.956  -0.815  -0.832  -0.830  -0.822  -0.839  -0.824
316   D        -0.937  -0.953  -0.956  -0.756  -0.786  -0.780  -0.822  -0.839  -0.824
317   T        -0.351  -0.378  -0.350  -0.603  -0.630  -0.574  -0.499  -0.527  -0.481
318   S        -0.351  -0.337  -0.333  -0.720  -0.684  -0.660  -0.499  -0.481  -0.460
319   I        -0.131  -0.099  -0.194  -0.058  -0.008  -0.160  -0.177  -0.132  -0.263
320   W         1.875   1.882   1.934   2.156   2.162   2.250   2.081   2.091   2.176
321   E        -0.937  -0.913  -0.927  -0.693  -0.665  -0.668  -0.822  -0.794  -0.794
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   D         0.455   0.466   0.502   0.339   0.355   0.410   0.146   0.165   0.211
326   E        -0.937  -0.905  -0.922  -1.062  -1.017  -1.019  -0.822  -0.785  -0.788
327   Q        -0.937  -0.945  -0.931  -0.964  -0.966  -0.922  -0.822  -0.830  -0.798
328   K        -0.351  -0.378  -0.350  -0.418  -0.456  -0.408  -0.499  -0.527  -0.481
329   Y        -0.351  -0.378  -0.350  -0.147  -0.192  -0.149  -0.499  -0.527  -0.481
330   G        -0.351  -0.378  -0.350  -0.333  -0.372  -0.311  -0.499  -0.527  -0.481
331   K        -0.937  -0.939  -0.954  -0.644  -0.649  -0.668  -0.822  -0.823  -0.823
332   A        -0.937  -0.953  -0.956  -0.767  -0.805  -0.814  -0.822  -0.839  -0.824
333   F         1.875   1.882   1.934   1.880   1.896   1.973   2.081   2.091   2.176
334   K        -0.937  -0.939  -0.954  -0.668  -0.670  -0.700  -0.822  -0.823  -0.823
335   V         0.819   0.759   0.676   0.948   0.853   0.724   0.791   0.689   0.533
336   R        -0.351  -0.378  -0.350  -0.387  -0.434  -0.384  -0.499  -0.527  -0.481
337   W         1.875   1.882   1.934   2.156   2.162   2.250   2.081   2.091   2.176
338   V        -0.351  -0.378  -0.350  -0.337  -0.363  -0.303  -0.499  -0.527  -0.481
339   I        -0.937  -0.940  -0.923  -0.730  -0.726  -0.694  -0.822  -0.824  -0.789
340   V         0.455   0.466   0.502   0.332   0.347   0.402   0.146   0.165   0.211
341   R        -0.131  -0.152  -0.240  -0.109  -0.149  -0.287  -0.177  -0.207  -0.326
342   D         1.875   1.882   1.934   1.945   1.955   2.039   2.081   2.091   2.176
343   I        -0.131  -0.085  -0.229  -0.017   0.051  -0.187  -0.177  -0.113  -0.311
344   N        -0.351  -0.329  -0.333  -0.401  -0.372  -0.382  -0.499  -0.473  -0.460
345   N         0.819   0.759   0.676   0.819   0.733   0.608   0.791   0.689   0.533
346   R        -0.131  -0.108  -0.199   0.035   0.063  -0.074  -0.177  -0.145  -0.269
347   S        -0.937  -0.945  -0.931  -0.780  -0.791  -0.800  -0.822  -0.830  -0.798
348   L         0.455   0.476   0.505   0.243   0.291   0.320   0.146   0.183   0.217
349   K        -0.351  -0.378  -0.350  -0.358  -0.399  -0.361  -0.499  -0.527  -0.481
350   R         0.455   0.476   0.505   0.534   0.569   0.611   0.146   0.183   0.217
351   F         0.455   0.476   0.505   0.238   0.287   0.316   0.146   0.183   0.217
352   L        -0.351  -0.378  -0.350  -0.483  -0.513  -0.465  -0.499  -0.527  -0.481
353   I        -0.131  -0.165  -0.228  -0.011  -0.054  -0.154  -0.177  -0.225  -0.309
354   P         0.819   0.759   0.676   1.044   0.950   0.822   0.791   0.689   0.533
355   S        -1.522  -1.514  -1.464  -1.502  -1.478  -1.411  -1.145  -1.135  -1.065
356   N         0.819   0.759   0.676   0.815   0.731   0.602   0.791   0.689   0.533
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   E         0.819   0.829   0.699   0.932   0.942   0.753   0.791   0.807   0.573
359   M        -0.937  -0.953  -0.956  -0.629  -0.654  -0.683  -0.822  -0.839  -0.824
360   K         1.875   1.882   1.934   1.855   1.866   1.948   2.081   2.091   2.176
361   P        -0.351  -0.343  -0.333  -0.570  -0.566  -0.557  -0.499  -0.487  -0.460
362   I        -0.351  -0.378  -0.350  -0.418  -0.458  -0.414  -0.499  -0.527  -0.481
363   T         0.819   0.759   0.676   0.941   0.857   0.736   0.791   0.689   0.533
364   H        -0.351  -0.337  -0.336  -0.344  -0.317  -0.305  -0.499  -0.482  -0.464
365   S         0.819   0.759   0.676   0.613   0.536   0.420   0.791   0.689   0.533
366   R         1.875   1.882   1.934   1.973   1.979   2.067   2.081   2.091   2.176
367   D         1.875   1.882   1.934   1.945   1.955   2.039   2.081   2.091   2.176
368   T         1.875   1.882   1.934   1.921   1.933   2.014   2.081   2.091   2.176
369   Q         0.819   0.759   0.676   1.102   1.009   0.878   0.791   0.689   0.533
370   E         0.819   0.759   0.676   0.920   0.826   0.697   0.791   0.689   0.533
371   I        -0.131  -0.165  -0.228  -0.058  -0.110  -0.216  -0.177  -0.225  -0.309
372   P         1.875   1.882   1.934   2.050   2.056   2.143   2.081   2.091   2.176
373   Y         0.819   0.857   0.702   0.915   0.973   0.758   0.791   0.853   0.579
374   S        -0.937  -0.939  -0.954  -0.933  -0.937  -0.985  -0.822  -0.823  -0.823
375   I         1.875   1.882   1.934   1.896   1.908   1.989   2.081   2.091   2.176
376   G         1.875   1.882   1.934   2.030   2.032   2.123   2.081   2.091   2.176
377   I        -0.937  -0.947  -0.922  -0.677  -0.689  -0.640  -0.822  -0.832  -0.788
378   S        -0.131  -0.163  -0.227  -0.306  -0.352  -0.430  -0.177  -0.223  -0.309
379   I        -0.351  -0.337  -0.336  -0.238  -0.226  -0.218  -0.499  -0.482  -0.464
380   I        -0.131  -0.152  -0.240  -0.079  -0.106  -0.250  -0.177  -0.207  -0.326
381   N        -0.937  -0.939  -0.954  -0.815  -0.816  -0.826  -0.822  -0.823  -0.823
382   L         0.455   0.476   0.505   0.257   0.302   0.334   0.146   0.183   0.217
383   F         0.819   0.829   0.699   0.884   0.903   0.708   0.791   0.807   0.573
384   K        -0.351  -0.378  -0.350  -0.608  -0.627  -0.564  -0.499  -0.527  -0.481
385   T        -0.131  -0.152  -0.240  -0.386  -0.415  -0.553  -0.177  -0.207  -0.326
386   Q        -0.937  -0.939  -0.954  -0.922  -0.941  -0.957  -0.822  -0.823  -0.823
387   D        -0.937  -0.939  -0.954  -0.862  -0.858  -0.881  -0.822  -0.823  -0.823
388   S         0.412   0.418   0.470  -0.013  -0.011   0.079   0.065   0.073   0.150
389   D        -0.319  -0.299  -0.308  -0.472  -0.437  -0.457  -0.439  -0.412  -0.421
390   I         0.532   0.477   0.514   0.297   0.169   0.220   0.289   0.185   0.233
391   F        -0.444  -0.428  -0.386  -0.802  -0.809  -0.711  -0.607  -0.585  -0.525
392   S        -0.444  -0.428  -0.386  -0.581  -0.564  -0.490  -0.607  -0.585  -0.525
393   F         0.532   0.477   0.514   0.409   0.290   0.350   0.289   0.185   0.233
394   L         0.532   0.477   0.514   0.368   0.263   0.324   0.289   0.185   0.233
395   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   E        -0.444  -0.431  -0.386  -0.581  -0.554  -0.490  -0.607  -0.590  -0.525
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06390
Output conservation file - output/Q06390
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
