1     M         1.111   1.123   1.184   1.320   1.334   1.421   1.187   1.204   1.295
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S        -0.197  -0.197  -0.534  -0.073  -0.082  -0.546  -0.185  -0.192  -0.646
6     T         0.047   0.077   0.077   0.051   0.093   0.072  -0.192  -0.143  -0.182
7     L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
8     Q        -0.197  -0.342  -0.559   0.150  -0.052  -0.436  -0.185  -0.379  -0.681
9     R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
10    R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
11    R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
12    V        -0.066  -0.036   0.036  -0.210  -0.170  -0.064  -0.397  -0.348  -0.259
13    N        -0.622  -0.573  -0.614  -0.645  -0.595  -0.616  -0.819  -0.772  -0.762
14    R        -1.546  -1.578  -1.486  -1.404  -1.455  -1.327  -1.347  -1.368  -1.216
15    A        -1.971  -1.899  -1.799  -1.726  -1.645  -1.491  -1.558  -1.497  -1.330
16    D        -1.971  -1.956  -1.811  -1.911  -1.889  -1.676  -1.558  -1.536  -1.337
17    S        -0.622  -0.547  -0.596  -0.708  -0.601  -0.637  -0.819  -0.714  -0.736
18    G        -1.645  -1.652  -1.496  -1.567  -1.592  -1.365  -1.433  -1.428  -1.223
19    D        -0.688  -0.669  -0.618  -0.856  -0.830  -0.745  -0.878  -0.852  -0.765
20    T        -1.665  -1.627  -1.503  -1.833  -1.775  -1.613  -1.441  -1.398  -1.228
21    S        -1.258  -1.253  -1.127  -1.258  -1.260  -1.105  -1.245  -1.235  -1.065
22    S        -1.099  -1.158  -1.113  -0.821  -0.926  -0.898  -1.065  -1.130  -1.050
23    I        -1.254  -1.273  -1.130  -1.280  -1.311  -1.110  -1.253  -1.260  -1.068
24    H        -1.665  -1.704  -1.521  -1.343  -1.401  -1.174  -1.441  -1.467  -1.243
25    S        -0.688  -0.709  -0.635  -0.849  -0.894  -0.770  -0.878  -0.905  -0.786
26    S        -1.665  -1.571  -1.499  -1.639  -1.519  -1.403  -1.441  -1.349  -1.224
27    A        -1.665  -1.704  -1.521  -1.672  -1.735  -1.465  -1.441  -1.467  -1.243
28    N        -1.665  -1.704  -1.521  -1.576  -1.629  -1.365  -1.441  -1.467  -1.243
29    N        -1.665  -1.704  -1.521  -1.510  -1.547  -1.279  -1.441  -1.467  -1.243
30    T        -1.099  -0.995  -1.095  -1.011  -0.876  -0.999  -1.065  -0.948  -1.031
31    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    V        -1.258  -1.214  -1.127  -1.261  -1.188  -1.110  -1.245  -1.192  -1.065
41    D        -1.160  -1.101  -1.102  -1.235  -1.136  -1.136  -1.157  -1.080  -1.039
42    G        -1.512  -1.488  -1.480  -1.095  -1.057  -1.084  -1.295  -1.270  -1.208
43    D        -1.998  -1.960  -1.807  -2.015  -1.992  -1.749  -1.571  -1.534  -1.334
44    D        -1.663  -1.650  -1.509  -1.672  -1.636  -1.439  -1.452  -1.429  -1.233
45    D        -0.490  -0.485  -0.601  -0.459  -0.491  -0.604  -0.608  -0.634  -0.742
46    N        -1.099  -1.144  -1.113  -0.919  -0.974  -0.970  -1.065  -1.124  -1.051
47    G        -1.855  -1.751  -1.783  -1.690  -1.559  -1.599  -1.452  -1.358  -1.316
48    T        -1.971  -1.923  -1.813  -1.652  -1.607  -1.444  -1.558  -1.510  -1.339
49    N        -1.046  -1.011  -1.092  -1.009  -0.979  -1.082  -1.030  -1.006  -1.031
50    K        -0.798  -0.753  -1.052  -0.292  -0.235  -0.721  -0.713  -0.659  -0.984
51    K         0.441   0.373   0.150   0.568   0.482   0.126   0.448   0.345  -0.049
52    I         1.111   1.123   1.184   1.182   1.202   1.294   1.187   1.204   1.295
53    A        -0.622  -0.572  -0.610  -0.664  -0.598  -0.629  -0.819  -0.751  -0.755
54    Y         0.111   0.032   0.048   0.303   0.170   0.150  -0.080  -0.223  -0.236
55    D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
56    P        -0.490  -0.380  -0.565  -0.344  -0.163  -0.511  -0.608  -0.448  -0.690
57    E        -1.238  -1.189  -1.112  -1.293  -1.219  -1.082  -1.241  -1.185  -1.052
58    E        -0.066  -0.018   0.047  -0.325  -0.235  -0.156  -0.397  -0.315  -0.238
59    S        -1.238  -1.214  -1.128  -1.471  -1.479  -1.326  -1.241  -1.215  -1.067
60    K        -1.046  -1.131  -1.104  -1.036  -1.176  -1.171  -1.030  -1.115  -1.044
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    L        -1.546  -1.615  -1.508  -1.793  -1.873  -1.656  -1.347  -1.391  -1.232
63    R        -1.546  -1.516  -1.490  -1.398  -1.390  -1.294  -1.347  -1.323  -1.218
64    D        -1.546  -1.397  -1.481  -1.561  -1.340  -1.457  -1.347  -1.199  -1.210
65    N        -1.971  -1.889  -1.814  -1.881  -1.771  -1.686  -1.558  -1.487  -1.340
66    I        -1.663  -1.599  -1.497  -1.929  -1.811  -1.603  -1.452  -1.393  -1.224
67    N        -0.197  -0.109  -0.530  -0.009   0.108  -0.522  -0.185  -0.068  -0.640
68    I        -0.798  -0.661  -1.030  -0.476  -0.280  -0.930  -0.713  -0.548  -0.961
69    P         1.111   1.123   1.184   1.305   1.320   1.408   1.187   1.204   1.295
70    T        -1.355  -1.319  -1.137  -1.608  -1.528  -1.259  -1.347  -1.305  -1.075
71    L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
72    T         1.111   1.123   1.184   1.230   1.245   1.338   1.187   1.204   1.295
73    L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
74    M         1.111   1.123   1.184   1.320   1.334   1.421   1.187   1.204   1.295
75    E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
76    E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
77    V         1.111   1.123   1.184   1.145   1.155   1.259   1.187   1.204   1.295
78    L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
79    L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
80    M         0.111   0.032   0.048   0.146  -0.028  -0.109  -0.080  -0.223  -0.236
81    G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
82    L         0.441   0.373   0.150   0.207   0.130  -0.172   0.448   0.345  -0.049
83    R         0.111   0.175   0.096   0.088   0.191   0.026  -0.080   0.026  -0.146
84    D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
85    R        -0.622  -0.642  -0.613  -0.682  -0.702  -0.624  -0.819  -0.833  -0.761
86    E        -0.066  -0.079   0.019  -0.226  -0.248  -0.077  -0.397  -0.428  -0.290
87    G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
88    Y         1.111   1.123   1.184   1.327   1.344   1.428   1.187   1.204   1.295
89    L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
90    S         1.111   1.123   1.184   1.067   1.084   1.187   1.187   1.204   1.295
91    F         1.111   1.123   1.184   1.282   1.298   1.386   1.187   1.204   1.295
92    W         1.111   1.123   1.184   1.401   1.414   1.496   1.187   1.204   1.295
93    N         1.111   1.123   1.184   1.195   1.217   1.306   1.187   1.204   1.295
94    D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
95    S        -0.066  -0.055   0.028  -0.228  -0.211  -0.111  -0.397  -0.383  -0.273
96    I         1.111   1.123   1.184   1.182   1.202   1.294   1.187   1.204   1.295
97    S         1.111   1.123   1.184   1.067   1.084   1.187   1.187   1.204   1.295
98    Y         1.111   1.123   1.184   1.327   1.344   1.428   1.187   1.204   1.295
99    A         0.441   0.359   0.148   0.571   0.458   0.113   0.448   0.324  -0.053
100   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
101   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
102   G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
103   C         1.111   1.123   1.184   1.409   1.424   1.505   1.187   1.204   1.295
104   I         1.111   1.123   1.184   1.182   1.202   1.294   1.187   1.204   1.295
105   I        -0.490  -0.541  -0.599  -0.789  -0.849  -0.895  -0.608  -0.666  -0.740
106   I        -0.814  -0.819  -0.663  -1.110  -1.095  -0.843  -1.030  -1.032  -0.819
107   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
108   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
109   A         0.441   0.534   0.164   0.594   0.700   0.201   0.448   0.581  -0.026
110   L        -0.622  -0.563  -0.613  -0.872  -0.792  -0.745  -0.819  -0.764  -0.762
111   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
112   G        -0.066   0.003   0.046  -0.169  -0.051  -0.008  -0.397  -0.276  -0.240
113   K         0.441   0.373   0.150   0.568   0.482   0.126   0.448   0.345  -0.049
114   I        -0.197  -0.316  -0.556  -0.037  -0.212  -0.674  -0.185  -0.344  -0.676
115   R        -1.046  -1.068  -1.092  -0.948  -0.969  -1.004  -1.030  -1.033  -1.028
116   I        -1.238  -1.140  -1.111  -1.232  -1.030  -1.000  -1.241  -1.126  -1.049
117   L        -0.738  -0.745  -0.641  -0.916  -0.912  -0.785  -0.925  -0.936  -0.792
118   D        -0.814  -0.822  -0.663  -0.970  -0.978  -0.744  -1.030  -1.036  -0.820
119   D         0.441   0.487   0.157   0.516   0.576   0.106   0.448   0.514  -0.037
120   S        -1.046  -1.138  -1.102  -0.849  -0.998  -0.987  -1.030  -1.122  -1.042
121   A        -0.490  -0.600  -0.621  -0.435  -0.615  -0.673  -0.608  -0.757  -0.769
122   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
123   K        -0.622  -0.586  -0.614  -0.690  -0.649  -0.626  -0.819  -0.778  -0.762
124   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
125   F         0.441   0.480   0.154   0.722   0.770   0.320   0.448   0.504  -0.042
126   D        -0.814  -0.748  -0.641  -0.943  -0.812  -0.676  -1.030  -0.946  -0.792
127   L        -0.490  -0.463  -0.591  -0.789  -0.749  -0.887  -0.608  -0.576  -0.730
128   S         0.111   0.032   0.048   0.017  -0.120  -0.113  -0.080  -0.223  -0.236
129   E        -0.066  -0.018   0.047  -0.325  -0.235  -0.156  -0.397  -0.315  -0.238
130   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
131   L        -0.798  -0.963  -1.089  -0.893  -1.105  -1.217  -0.713  -0.904  -1.025
132   I        -0.066  -0.041   0.034  -0.199  -0.158  -0.062  -0.397  -0.357  -0.261
133   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
134   V         0.441   0.359   0.148   0.510   0.387  -0.011   0.448   0.324  -0.053
135   I         0.441   0.359   0.148   0.597   0.494   0.156   0.448   0.324  -0.053
136   D         0.441   0.403   0.148   0.520   0.478   0.101   0.448   0.390  -0.053
137   S        -1.971  -1.909  -1.814  -1.898  -1.828  -1.661  -1.558  -1.503  -1.340
138   S        -1.238  -1.253  -1.130  -1.363  -1.364  -1.167  -1.241  -1.245  -1.069
139   K        -0.814  -0.748  -0.641  -1.135  -1.080  -0.876  -1.030  -0.946  -0.792
140   T         1.111   1.123   1.184   1.230   1.245   1.338   1.187   1.204   1.295
141   G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
142   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
143   V         0.441   0.403   0.148   0.563   0.509   0.131   0.448   0.390  -0.053
144   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
145   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
146   D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
147   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
148   T        -0.622  -0.582  -0.615  -0.653  -0.602  -0.641  -0.819  -0.768  -0.763
149   L         0.111   0.047   0.044  -0.250  -0.345  -0.331  -0.080  -0.197  -0.243
150   Q        -0.490  -0.410  -0.582  -0.399  -0.282  -0.556  -0.608  -0.494  -0.713
151   L        -0.814  -0.822  -0.663  -1.110  -1.086  -0.826  -1.030  -1.036  -0.820
152   M         0.441   0.359   0.148   0.739   0.634   0.289   0.448   0.324  -0.053
153   K        -0.197  -0.240  -0.540   0.039  -0.010  -0.433  -0.185  -0.246  -0.655
154   N        -0.490  -0.588  -0.621  -0.377  -0.532  -0.595  -0.608  -0.748  -0.768
155   D        -0.066  -0.096   0.018  -0.315  -0.386  -0.208  -0.397  -0.459  -0.292
156   E         0.441   0.480   0.154   0.487   0.534   0.111   0.448   0.504  -0.042
157   P        -1.238  -1.258  -1.131  -1.277  -1.325  -1.201  -1.241  -1.249  -1.070
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   L        -0.490  -0.528  -0.609  -0.713  -0.761  -0.790  -0.608  -0.680  -0.752
160   S         0.441   0.403   0.148   0.495   0.449   0.089   0.448   0.390  -0.053
161   I        -0.066  -0.018   0.047  -0.212  -0.134  -0.045  -0.397  -0.315  -0.238
162   S        -1.546  -1.529  -1.486  -1.403  -1.393  -1.341  -1.347  -1.326  -1.215
163   N        -1.046  -1.097  -1.113  -0.939  -1.044  -1.054  -1.030  -1.094  -1.052
164   W         1.111   1.123   1.184   1.401   1.414   1.496   1.187   1.204   1.295
165   I         1.111   1.123   1.184   1.182   1.202   1.294   1.187   1.204   1.295
166   D         0.441   0.403   0.148   0.520   0.478   0.101   0.448   0.390  -0.053
167   L         0.441   0.403   0.148   0.230   0.194  -0.114   0.448   0.390  -0.053
168   L         0.111   0.032   0.048  -0.201  -0.308  -0.244  -0.080  -0.223  -0.236
169   S         1.111   1.123   1.184   1.067   1.084   1.187   1.187   1.204   1.295
170   G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
171   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
172   T         1.111   1.123   1.184   1.230   1.245   1.338   1.187   1.204   1.295
173   W         1.111   1.123   1.184   1.401   1.414   1.496   1.187   1.204   1.295
174   N         1.111   1.123   1.184   1.195   1.217   1.306   1.187   1.204   1.295
175   L         0.441   0.359   0.148   0.201   0.103  -0.191   0.448   0.324  -0.053
176   L        -0.622  -0.623  -0.617  -0.791  -0.755  -0.773  -0.819  -0.803  -0.762
177   K         1.111   1.123   1.184   1.158   1.176   1.271   1.187   1.204   1.295
178   I         1.111   1.123   1.184   1.182   1.202   1.294   1.187   1.204   1.295
179   N        -0.490  -0.588  -0.621  -0.412  -0.577  -0.658  -0.608  -0.748  -0.768
180   Y         1.111   1.123   1.184   1.327   1.344   1.428   1.187   1.204   1.295
181   Q         1.111   1.123   1.184   1.312   1.327   1.415   1.187   1.204   1.295
182   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
183   K         0.441   0.359   0.148   0.568   0.463   0.122   0.448   0.324  -0.053
184   Q         1.111   1.123   1.184   1.312   1.327   1.415   1.187   1.204   1.295
185   V         1.111   1.123   1.184   1.145   1.155   1.259   1.187   1.204   1.295
186   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
187   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
188   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
189   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
190   A         0.441   0.403   0.148   0.571   0.517   0.113   0.448   0.390  -0.053
191   K         1.111   1.123   1.184   1.158   1.176   1.271   1.187   1.204   1.295
192   G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
193   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
194   V         1.111   1.123   1.184   1.145   1.155   1.259   1.187   1.204   1.295
195   D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
196   K         1.111   1.123   1.184   1.158   1.176   1.271   1.187   1.204   1.295
197   G         1.111   1.123   1.184   1.186   1.196   1.297   1.187   1.204   1.295
198   V        -0.066  -0.018   0.047  -0.199  -0.114  -0.036  -0.397  -0.315  -0.238
199   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
200   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
201   T         0.441   0.359   0.148   0.652   0.549   0.216   0.448   0.324  -0.053
202   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
203   M        -0.814  -0.748  -0.641  -0.865  -0.772  -0.626  -1.030  -0.946  -0.792
204   K         0.111   0.054   0.049   0.088  -0.016  -0.069  -0.080  -0.184  -0.235
205   N         1.111   1.123   1.184   1.195   1.217   1.306   1.187   1.204   1.295
206   F         1.111   1.123   1.184   1.282   1.298   1.386   1.187   1.204   1.295
207   F         0.111   0.032   0.048   0.109  -0.063  -0.141  -0.080  -0.223  -0.236
208   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
209   F         1.111   1.123   1.184   1.282   1.298   1.386   1.187   1.204   1.295
210   D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
211   M         1.111   1.123   1.184   1.320   1.334   1.421   1.187   1.204   1.295
212   A         0.111   0.047   0.044   0.159   0.050   0.035  -0.080  -0.197  -0.243
213   T         1.111   1.123   1.184   1.230   1.245   1.338   1.187   1.204   1.295
214   H         1.111   1.123   1.184   1.402   1.416   1.498   1.187   1.204   1.295
215   P         1.111   1.123   1.184   1.305   1.320   1.408   1.187   1.204   1.295
216   I        -0.066  -0.057   0.027  -0.212  -0.206  -0.083  -0.397  -0.386  -0.275
217   A        -0.798  -0.801  -1.044  -0.558  -0.573  -0.957  -0.713  -0.716  -0.976
218   D         0.441   0.373   0.150   0.499   0.413   0.048   0.448   0.345  -0.049
219   A        -1.546  -1.485  -1.474  -1.375  -1.272  -1.292  -1.347  -1.276  -1.203
220   S        -1.855  -1.810  -1.796  -1.707  -1.642  -1.647  -1.452  -1.410  -1.326
221   C        -1.238  -1.258  -1.131  -1.097  -1.129  -0.980  -1.241  -1.249  -1.070
222   K         1.111   1.123   1.184   1.158   1.176   1.271   1.187   1.204   1.295
223   E         0.441   0.359   0.148   0.456   0.349   0.020   0.448   0.324  -0.053
224   A        -1.355  -1.320  -1.138  -1.403  -1.377  -1.111  -1.347  -1.306  -1.076
225   I         1.111   1.123   1.184   1.182   1.202   1.294   1.187   1.204   1.295
226   K         0.441   0.373   0.150   0.568   0.482   0.126   0.448   0.345  -0.049
227   R        -0.738  -0.715  -0.635  -0.840  -0.814  -0.701  -0.925  -0.897  -0.785
228   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
229   V        -0.122  -0.095   0.026  -0.317  -0.277  -0.085  -0.502  -0.458  -0.277
230   L        -0.197  -0.342  -0.559  -0.383  -0.574  -0.882  -0.185  -0.379  -0.681
231   S         0.111   0.112   0.057   0.027   0.027  -0.082  -0.080  -0.083  -0.219
232   V        -1.046  -0.949  -1.085  -1.088  -0.960  -1.153  -1.030  -0.923  -1.024
233   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
234   V        -0.622  -0.579  -0.619  -0.645  -0.602  -0.611  -0.819  -0.782  -0.768
235   S        -0.197  -0.303  -0.554  -0.062  -0.198  -0.551  -0.185  -0.326  -0.673
236   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
237   N        -0.490  -0.606  -0.621  -0.381  -0.556  -0.603  -0.608  -0.762  -0.769
238   M        -1.046  -1.046  -1.093  -0.886  -0.888  -0.955  -1.030  -1.016  -1.030
239   E        -0.738  -0.711  -0.635  -0.945  -0.908  -0.796  -0.925  -0.891  -0.784
240   L        -0.066  -0.078   0.019  -0.528  -0.537  -0.347  -0.397  -0.426  -0.290
241   S        -1.663  -1.632  -1.499  -1.668  -1.610  -1.422  -1.452  -1.419  -1.226
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   Y        -1.546  -1.517  -1.500  -1.217  -1.188  -1.205  -1.347  -1.324  -1.226
245   N        -0.490  -0.600  -0.621  -0.426  -0.604  -0.662  -0.608  -0.757  -0.769
246   E        -1.971  -1.919  -1.805  -1.743  -1.633  -1.517  -1.558  -1.508  -1.334
247   Y        -0.490  -0.482  -0.574  -0.242  -0.221  -0.415  -0.608  -0.576  -0.702
248   F         0.111   0.054   0.049   0.109  -0.016  -0.138  -0.080  -0.184  -0.235
249   P         1.111   1.123   1.184   1.305   1.320   1.408   1.187   1.204   1.295
250   E        -0.490  -0.380  -0.565  -0.511  -0.348  -0.587  -0.608  -0.448  -0.690
251   T        -1.355  -1.377  -1.465  -1.114  -1.143  -1.277  -1.136  -1.158  -1.195
252   T        -0.738  -0.781  -0.661  -0.915  -1.047  -0.889  -0.925  -0.982  -0.818
253   S        -0.798  -0.863  -1.062  -0.635  -0.729  -1.020  -0.713  -0.790  -0.996
254   F         1.111   1.123   1.184   1.282   1.298   1.386   1.187   1.204   1.295
255   K        -0.122  -0.098   0.023  -0.358  -0.322  -0.128  -0.502  -0.463  -0.283
256   I        -0.798  -0.789  -1.053  -0.410  -0.388  -0.865  -0.713  -0.705  -0.985
257   I        -0.622  -0.644  -0.615  -0.981  -0.999  -0.914  -0.819  -0.826  -0.760
258   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
259   T         0.111   0.130   0.060   0.143   0.170  -0.010  -0.080  -0.051  -0.214
260   L        -0.738  -0.700  -0.631  -0.976  -0.902  -0.838  -0.925  -0.873  -0.778
261   A        -0.622  -0.618  -0.598  -0.729  -0.704  -0.663  -0.819  -0.795  -0.741
262   L        -0.197  -0.303  -0.554  -0.341  -0.467  -0.773  -0.185  -0.326  -0.673
263   I        -0.622  -0.654  -0.617  -0.680  -0.713  -0.650  -0.819  -0.837  -0.763
264   C         0.441   0.487   0.157   0.826   0.882   0.376   0.448   0.514  -0.037
265   G        -0.197  -0.342  -0.559   0.015  -0.193  -0.562  -0.185  -0.379  -0.681
266   S        -0.066  -0.048   0.025  -0.253  -0.230  -0.139  -0.397  -0.369  -0.278
267   Y         0.441   0.373   0.150   0.777   0.698   0.380   0.448   0.345  -0.049
268   G        -0.066  -0.018   0.047  -0.190  -0.116  -0.025  -0.397  -0.315  -0.238
269   A         1.111   1.123   1.184   1.167   1.178   1.280   1.187   1.204   1.295
270   N         1.111   1.123   1.184   1.195   1.217   1.306   1.187   1.204   1.295
271   V         1.111   1.123   1.184   1.145   1.155   1.259   1.187   1.204   1.295
272   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
273   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
274   N         1.111   1.123   1.184   1.195   1.217   1.306   1.187   1.204   1.295
275   V         0.111   0.032   0.048   0.092  -0.053  -0.052  -0.080  -0.223  -0.236
276   L         0.441   0.487   0.157   0.207   0.271  -0.162   0.448   0.514  -0.037
277   T        -1.663  -1.646  -1.497  -1.876  -1.825  -1.566  -1.452  -1.428  -1.224
278   T        -1.122  -1.178  -1.103  -1.118  -1.174  -1.068  -1.136  -1.175  -1.043
279   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
280   E        -1.546  -1.566  -1.496  -1.483  -1.501  -1.433  -1.347  -1.351  -1.222
281   Y         0.441   0.373   0.150   0.777   0.698   0.380   0.448   0.345  -0.049
282   E         0.111   0.181   0.068  -0.024   0.088  -0.128  -0.080   0.037  -0.199
283   K        -1.355  -1.471  -1.489  -1.076  -1.254  -1.302  -1.136  -1.250  -1.216
284   R         1.111   1.123   1.184   1.113   1.126   1.229   1.187   1.204   1.295
285   D         0.111   0.032   0.048   0.008  -0.136  -0.154  -0.080  -0.223  -0.236
286   K        -1.122  -1.132  -1.106  -0.965  -0.979  -0.929  -1.136  -1.136  -1.046
287   A         0.441   0.480   0.154   0.588   0.631   0.169   0.448   0.504  -0.042
288   I         0.111   0.175   0.096   0.229   0.331   0.160  -0.080   0.026  -0.146
289   S        -0.622  -0.597  -0.611  -0.719  -0.709  -0.678  -0.819  -0.796  -0.759
290   R         0.441   0.373   0.150   0.553   0.470   0.167   0.448   0.345  -0.049
291   A         0.441   0.359   0.148   0.582   0.471   0.143   0.448   0.324  -0.053
292   E         0.111   0.175   0.096   0.008   0.115  -0.055  -0.080   0.026  -0.146
293   E         0.441   0.403   0.148   0.456   0.408   0.020   0.448   0.390  -0.053
294   I        -0.066  -0.018   0.047  -0.528  -0.449  -0.327  -0.397  -0.315  -0.238
295   M         0.441   0.508   0.163   0.229   0.315  -0.096   0.448   0.544  -0.027
296   A        -1.046  -1.145  -1.105  -0.952  -1.097  -1.068  -1.030  -1.125  -1.045
297   Q        -0.122  -0.106   0.018  -0.255  -0.233  -0.041  -0.502  -0.479  -0.292
298   F         0.441   0.373   0.150   0.722   0.641   0.313   0.448   0.345  -0.049
299   S         1.111   1.123   1.184   1.067   1.084   1.187   1.187   1.204   1.295
300   Q        -0.122  -0.103   0.019  -0.290  -0.251  -0.065  -0.502  -0.472  -0.290
301   Y        -0.814  -0.760  -0.646  -0.642  -0.552  -0.407  -1.030  -0.959  -0.798
302   P         1.111   1.123   1.184   1.305   1.320   1.408   1.187   1.204   1.295
303   F         1.111   1.123   1.184   1.282   1.298   1.386   1.187   1.204   1.295
304   D        -1.546  -1.551  -1.489  -1.409  -1.410  -1.308  -1.347  -1.335  -1.216
305   L        -0.197  -0.303  -0.554  -0.391  -0.528  -0.892  -0.185  -0.326  -0.673
306   E        -2.279  -2.285  -2.088  -2.012  -1.999  -1.734  -1.664  -1.657  -1.425
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   K        -0.808  -0.789  -0.656  -0.739  -0.716  -0.514  -1.019  -0.997  -0.812
310   E        -0.808  -0.802  -0.658  -0.868  -0.884  -0.672  -1.019  -1.012  -0.813
311   T        -1.546  -1.628  -1.500  -1.401  -1.505  -1.301  -1.347  -1.405  -1.226
312   E        -1.971  -1.954  -1.810  -1.756  -1.743  -1.561  -1.558  -1.534  -1.337
313   L        -1.855  -1.919  -1.807  -1.911  -1.984  -1.756  -1.452  -1.501  -1.334
314   G        -0.197  -0.316  -0.556   0.019  -0.149  -0.545  -0.185  -0.344  -0.676
315   V        -0.490  -0.358  -0.583  -0.512  -0.313  -0.727  -0.608  -0.431  -0.718
316   S        -0.066  -0.018   0.047  -0.236  -0.153  -0.074  -0.397  -0.315  -0.238
317   V        -1.046  -0.982  -1.097  -1.006  -0.950  -1.122  -1.030  -0.984  -1.036
318   N         1.111   1.123   1.184   1.195   1.217   1.306   1.187   1.204   1.295
319   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
320   N        -1.238  -1.241  -1.132  -1.108  -1.094  -0.933  -1.241  -1.235  -1.071
321   K        -0.622  -0.654  -0.617  -0.582  -0.614  -0.589  -0.819  -0.837  -0.763
322   E        -0.490  -0.562  -0.602  -0.621  -0.745  -0.861  -0.608  -0.695  -0.743
323   V        -0.622  -0.540  -0.602  -0.748  -0.602  -0.756  -0.819  -0.702  -0.745
324   K        -1.663  -1.597  -1.500  -1.567  -1.487  -1.321  -1.452  -1.392  -1.226
325   E        -0.622  -0.572  -0.610  -0.782  -0.708  -0.700  -0.819  -0.751  -0.755
326   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
327   I        -0.622  -0.666  -0.612  -0.896  -0.966  -0.873  -0.819  -0.861  -0.759
328   E        -1.046  -1.145  -1.109  -1.057  -1.203  -1.143  -1.030  -1.131  -1.049
329   N        -1.663  -1.632  -1.499  -1.642  -1.604  -1.408  -1.452  -1.419  -1.226
330   N        -1.855  -1.833  -1.798  -1.447  -1.439  -1.381  -1.452  -1.431  -1.328
331   P        -0.738  -0.723  -0.637  -0.729  -0.714  -0.626  -0.925  -0.909  -0.786
332   G        -1.855  -1.874  -1.815  -1.638  -1.697  -1.657  -1.452  -1.466  -1.340
333   H        -1.238  -1.264  -1.126  -1.223  -1.274  -1.052  -1.241  -1.255  -1.065
334   D        -0.622  -0.654  -0.617  -0.782  -0.800  -0.706  -0.819  -0.837  -0.763
335   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
336   Q        -0.197  -0.240  -0.540   0.096   0.020  -0.527  -0.185  -0.246  -0.655
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   L         0.441   0.359   0.148   0.207   0.112  -0.175   0.448   0.324  -0.053
339   E         1.111   1.123   1.184   1.048   1.063   1.169   1.187   1.204   1.295
340   V         0.111   0.210   0.111  -0.027   0.146  -0.096  -0.080   0.085  -0.120
341   I        -0.122  -0.092   0.028  -0.317  -0.271  -0.081  -0.502  -0.452  -0.274
342   A         1.111   1.123   1.184   1.167   1.178   1.280   1.187   1.204   1.295
343   G        -0.122  -0.105   0.018  -0.298  -0.282  -0.080  -0.502  -0.477  -0.292
344   V         0.441   0.373   0.150   0.598   0.515   0.229   0.448   0.345  -0.049
345   F        -0.122  -0.105   0.018  -0.497  -0.479  -0.269  -0.502  -0.477  -0.292
346   E        -1.122  -1.181  -1.116  -1.223  -1.284  -1.153  -1.136  -1.179  -1.055
347   V         0.441   0.403   0.148   0.565   0.513   0.137   0.448   0.390  -0.053
348   F         1.111   1.123   1.184   1.282   1.298   1.386   1.187   1.204   1.295
349   S        -0.814  -0.822  -0.663  -0.977  -0.985  -0.737  -1.030  -1.036  -0.820
350   R        -0.197  -0.316  -0.556   0.003  -0.145  -0.472  -0.185  -0.344  -0.676
351   M        -0.066  -0.096   0.018  -0.256  -0.377  -0.233  -0.397  -0.459  -0.292
352   D         1.111   1.123   1.184   1.097   1.118   1.215   1.187   1.204   1.295
353   M        -0.490  -0.410  -0.582  -0.450  -0.339  -0.560  -0.608  -0.494  -0.713
354   L        -0.066  -0.026   0.037  -0.528  -0.462  -0.339  -0.397  -0.330  -0.256
355   L         1.111   1.123   1.184   0.787   0.811   0.927   1.187   1.204   1.295
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06385
Output conservation file - output/Q06385
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
