1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    L         0.556   0.641   0.727   0.450   0.625   0.727   0.204   0.366   0.471
45    K        -1.094  -1.029  -1.041  -0.853  -0.766  -0.793  -0.969  -0.906  -0.873
46    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    K         1.867   1.885   2.013   1.799   1.832   2.036   2.159   2.192   2.435
49    R         0.753   0.731   0.714   0.832   0.784   0.685   0.595   0.544   0.443
50    K        -0.261  -0.283  -0.486   0.159   0.129  -0.178  -0.187  -0.222  -0.479
51    N        -0.537  -0.537  -0.557  -0.403  -0.394  -0.442  -0.578  -0.562  -0.575
52    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    E         0.533   0.538   0.651  -0.046  -0.070   0.108   0.157   0.153   0.307
54    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    N        -0.664  -0.710  -0.647  -0.871  -0.939  -0.870  -0.735  -0.781  -0.687
65    G         0.289   0.232   0.090   0.239   0.158  -0.035   0.286   0.196  -0.037
66    S        -1.990  -1.953  -1.823  -1.815  -1.739  -1.588  -1.416  -1.382  -1.227
67    D        -0.537  -0.587  -0.582  -0.776  -0.851  -0.864  -0.578  -0.636  -0.616
68    E         0.493   0.520   0.650  -0.076  -0.040   0.164   0.074   0.115   0.306
69    S         0.409   0.251   0.096   0.584   0.379   0.163   0.465   0.227  -0.027
70    E        -1.094  -1.170  -1.082  -1.230  -1.303  -1.162  -0.969  -1.031  -0.910
71    I        -0.537  -0.646  -0.609  -0.498  -0.645  -0.624  -0.578  -0.701  -0.648
72    D         0.409   0.317   0.117   0.354   0.219  -0.112   0.465   0.327   0.007
73    I        -0.751  -0.797  -0.690  -0.954  -1.047  -0.913  -0.839  -0.881  -0.739
74    S         0.409   0.265   0.099   0.543   0.350   0.085   0.465   0.247  -0.022
75    S         0.409   0.251   0.096   0.486   0.251  -0.039   0.465   0.227  -0.027
76    T        -0.261  -0.438  -0.552   0.026  -0.253  -0.475  -0.187  -0.421  -0.564
77    D         0.409   0.317   0.117   0.415   0.292   0.009   0.465   0.327   0.007
78    S         0.409   0.317   0.117   0.570   0.452   0.167   0.465   0.327   0.007
79    E        -0.064  -0.019  -0.052  -0.471  -0.441  -0.430  -0.317  -0.279  -0.281
80    N        -1.224  -1.133  -1.107  -1.221  -1.094  -1.065  -1.099  -1.017  -0.939
81    E        -0.027  -0.104  -0.063  -0.277  -0.390  -0.318  -0.224  -0.340  -0.290
82    E        -0.664  -0.523  -0.604  -0.993  -0.781  -0.907  -0.735  -0.571  -0.635
83    E        -1.056  -1.078  -1.076  -1.151  -1.237  -1.194  -0.905  -0.937  -0.901
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    Q         0.533   0.530   0.651   0.324   0.286   0.447   0.157   0.137   0.307
88    N        -0.224  -0.249  -0.135  -0.317  -0.377  -0.231  -0.510  -0.541  -0.389
89    G         0.148   0.023  -0.021   0.388   0.159   0.061   0.074  -0.125  -0.212
90    -        -0.310  -0.285  -0.151  -0.731  -0.712  -0.497  -0.621  -0.588  -0.411
91    -         0.974   1.037   0.876   0.865   0.951   0.738   1.000   1.106   0.777
92    E        -1.056  -1.139  -1.125  -1.095  -1.265  -1.177  -0.905  -0.998  -0.951
93    E        -0.664  -0.744  -0.643  -0.682  -0.771  -0.602  -0.735  -0.814  -0.682
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   E         0.493   0.527   0.654  -0.076  -0.023   0.173   0.074   0.129   0.314
101   I         0.083   0.030  -0.006   0.154   0.084   0.017  -0.057  -0.134  -0.201
102   V         0.556   0.625   0.690   0.370   0.501   0.565   0.204   0.333   0.392
103   N         0.753   0.751   0.738   0.711   0.706   0.608   0.595   0.582   0.493
104   I         0.556   0.641   0.727   0.372   0.535   0.641   0.204   0.366   0.471
105   D         1.867   1.885   2.013   1.709   1.734   1.946   2.159   2.192   2.435
106   F         1.867   1.885   2.013   1.969   1.999   2.206   2.159   2.192   2.435
107   D         0.556   0.526   0.650   0.065  -0.024   0.163   0.204   0.128   0.305
108   F         0.083  -0.002  -0.013   0.189   0.062   0.016  -0.057  -0.173  -0.211
109   F         1.867   1.885   2.013   1.969   1.999   2.206   2.159   2.192   2.435
110   G         0.083   0.126  -0.002  -0.034   0.005  -0.140  -0.057  -0.016  -0.199
111   G        -1.094  -1.186  -1.124  -0.866  -0.990  -0.902  -0.969  -1.049  -0.951
112   N         0.409   0.251   0.096   0.652   0.433   0.174   0.465   0.227  -0.027
113   P         0.753   0.676   0.711   0.818   0.663   0.665   0.595   0.435   0.437
114   E         0.289   0.390   0.104   0.198   0.337  -0.089   0.286   0.434  -0.014
115   V         0.493   0.531   0.656   0.244   0.318   0.497   0.074   0.138   0.319
116   D         1.867   1.885   2.013   1.709   1.734   1.946   2.159   2.192   2.435
117   F         1.120   1.086   0.931   1.332   1.296   1.099   1.247   1.188   0.884
118   H         1.867   1.885   2.013   2.167   2.193   2.405   2.159   2.192   2.435
119   A         1.120   1.012   0.917   1.343   1.204   1.088   1.247   1.063   0.857
120   L        -1.224  -1.212  -1.111  -1.251  -1.208  -1.057  -1.099  -1.080  -0.941
121   K         1.120   1.086   0.931   1.164   1.130   0.936   1.247   1.188   0.884
122   N         0.409   0.384   0.132   0.719   0.683   0.362   0.465   0.416   0.030
123   L         0.753   0.811   0.786   0.593   0.686   0.628   0.595   0.698   0.593
124   L         0.409   0.562   0.167   0.487   0.683   0.172   0.465   0.687   0.085
125   R         1.120   1.070   0.929   1.390   1.324   1.109   1.247   1.163   0.880
126   Q         1.867   1.885   2.013   2.052   2.077   2.289   2.159   2.192   2.435
127   L         1.867   1.885   2.013   1.761   1.792   1.998   2.159   2.192   2.435
128   F         0.556   0.563   0.659   0.335   0.338   0.444   0.204   0.206   0.324
129   G         0.753   0.676   0.711   0.807   0.638   0.635   0.595   0.435   0.437
130   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   Q        -1.094  -1.186  -1.124  -0.955  -1.092  -1.017  -0.969  -1.049  -0.951
132   E         0.556   0.641   0.727   0.065   0.224   0.336   0.204   0.366   0.471
133   S        -0.537  -0.579  -0.610  -0.429  -0.488  -0.501  -0.578  -0.635  -0.649
134   T        -0.537  -0.539  -0.557  -0.305  -0.285  -0.308  -0.578  -0.566  -0.575
135   R        -1.438  -1.505  -1.489  -1.154  -1.306  -1.346  -1.099  -1.162  -1.101
136   I        -0.194  -0.119  -0.092  -0.268  -0.138  -0.144  -0.448  -0.340  -0.325
137   Q        -0.278  -0.263  -0.136  -0.433  -0.427  -0.271  -0.578  -0.557  -0.389
138   L         1.120   1.191   0.943   1.104   1.199   0.873   1.247   1.359   0.909
139   S         1.867   1.885   2.013   1.852   1.881   2.089   2.159   2.192   2.435
140   S        -0.751  -0.769  -0.654  -0.940  -0.951  -0.775  -0.839  -0.845  -0.702
141   L         1.120   1.156   0.938   1.103   1.156   0.863   1.247   1.304   0.899
142   A         0.556   0.549   0.653   0.391   0.357   0.496   0.204   0.176   0.313
143   D         1.120   1.203   0.947   1.060   1.162   0.844   1.247   1.379   0.916
144   L         0.753   0.676   0.711   0.636   0.519   0.568   0.595   0.435   0.437
145   I         1.867   1.885   2.013   1.914   1.948   2.152   2.159   2.192   2.435
146   L         1.120   1.012   0.917   1.103   0.969   0.828   1.247   1.063   0.857
147   -        -0.773  -0.691  -0.667  -0.906  -0.800  -0.744  -0.844  -0.745  -0.708
148   -        -0.016   0.116  -0.018  -0.017   0.206  -0.095  -0.177   0.021  -0.207
149   G        -1.438  -1.359  -1.432  -1.213  -1.099  -1.262  -1.099  -1.025  -1.052
150   S         0.409   0.251   0.096   0.536   0.321   0.064   0.465   0.227  -0.027
151   P        -1.094  -1.186  -1.124  -0.842  -0.975  -0.895  -0.969  -1.049  -0.951
152   T         0.556   0.641   0.727   0.546   0.693   0.815   0.204   0.366   0.471
153   T         0.753   0.669   0.712   0.789   0.631   0.652   0.595   0.421   0.438
154   T         1.120   1.156   0.938   1.337   1.388   1.082   1.247   1.304   0.899
155   I         0.409   0.251   0.096   0.663   0.472   0.254   0.465   0.227  -0.027
156   K         1.867   1.885   2.013   1.799   1.832   2.036   2.159   2.192   2.435
157   T         0.753   0.669   0.712   0.811   0.661   0.687   0.595   0.421   0.438
158   D         0.753   0.811   0.786   0.451   0.543   0.457   0.595   0.698   0.593
159   G         1.120   1.012   0.917   1.380   1.222   1.064   1.247   1.063   0.857
160   K         0.083   0.079   0.014   0.082   0.091  -0.001  -0.057  -0.051  -0.162
161   E         0.409   0.251   0.096   0.411   0.197  -0.019   0.465   0.227  -0.027
162   S         1.120   1.012   0.917   1.202   1.067   0.935   1.247   1.063   0.857
163   D         1.867   1.885   2.013   1.709   1.734   1.946   2.159   2.192   2.435
164   P         1.120   1.012   0.917   1.400   1.257   1.129   1.247   1.063   0.857
165   Y         0.556   0.579   0.673   0.526   0.560   0.684   0.204   0.238   0.355
166   C         0.556   0.641   0.727   0.590   0.715   0.852   0.204   0.366   0.471
167   F        -0.064  -0.090  -0.058  -0.086  -0.106  -0.041  -0.317  -0.343  -0.287
168   L         1.867   1.885   2.013   1.761   1.792   1.998   2.159   2.192   2.435
169   S         0.753   0.676   0.711   0.692   0.563   0.597   0.595   0.435   0.437
170   F         0.556   0.641   0.727   0.400   0.557   0.668   0.204   0.366   0.471
171   V         0.409   0.375   0.130   0.584   0.531   0.154   0.465   0.404   0.028
172   D         0.753   0.850   0.815   0.711   0.884   0.773   0.595   0.772   0.654
173   F        -1.224  -1.208  -1.116  -1.061  -1.056  -0.912  -1.099  -1.079  -0.946
174   K        -1.094  -1.186  -1.124  -0.956  -1.040  -0.942  -0.969  -1.049  -0.951
175   A        -1.094  -1.099  -1.045  -1.139  -1.150  -1.063  -0.969  -0.961  -0.872
176   N         0.083  -0.028  -0.041   0.284   0.131   0.127  -0.057  -0.233  -0.256
177   H        -1.094  -1.025  -1.070  -0.983  -0.889  -0.928  -0.969  -0.911  -0.902
178   L        -0.537  -0.530  -0.573  -0.725  -0.728  -0.818  -0.578  -0.566  -0.597
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   S        -0.621  -0.617  -0.620  -0.822  -0.813  -0.824  -0.708  -0.692  -0.658
182   D        -1.094  -1.158  -1.109  -1.065  -1.155  -1.028  -0.969  -1.027  -0.938
183   Y        -0.621  -0.629  -0.621  -0.422  -0.435  -0.366  -0.708  -0.708  -0.659
184   V        -0.751  -0.677  -0.648  -0.816  -0.704  -0.682  -0.839  -0.756  -0.693
185   K         0.753   0.676   0.711   0.633   0.505   0.537   0.595   0.435   0.437
186   Y        -0.621  -0.586  -0.609  -0.401  -0.352  -0.356  -0.708  -0.661  -0.645
187   L         1.120   1.191   0.943   1.104   1.199   0.873   1.247   1.359   0.909
188   -        -0.016   0.051  -0.011   0.024   0.128   0.009  -0.177  -0.080  -0.195
189   -        -0.224  -0.213  -0.104  -0.695  -0.680  -0.519  -0.510  -0.495  -0.347
190   -         1.867   1.885   2.013   2.061   2.090   2.299   2.159   2.192   2.435
191   -        -0.773  -0.750  -0.667  -0.850  -0.833  -0.718  -0.844  -0.820  -0.708
192   -        -0.773  -0.803  -0.700  -0.963  -1.016  -0.862  -0.844  -0.880  -0.747
193   -        -1.323  -1.287  -1.159  -1.345  -1.327  -1.117  -1.177  -1.141  -0.983
194   -         0.533   0.545   0.659   0.316   0.334   0.511   0.157   0.167   0.326
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   Q        -1.094  -1.105  -1.089  -0.794  -0.815  -0.782  -0.969  -0.970  -0.917
197   K         0.409   0.426   0.140   0.506   0.537   0.131   0.465   0.486   0.042
198   V        -1.567  -1.547  -1.478  -1.615  -1.581  -1.527  -1.230  -1.208  -1.094
199   D        -1.094  -1.158  -1.109  -1.176  -1.248  -1.174  -0.969  -1.027  -0.938
200   M        -1.567  -1.559  -1.457  -1.357  -1.387  -1.224  -1.230  -1.218  -1.079
201   R        -0.621  -0.630  -0.620  -0.727  -0.753  -0.725  -0.708  -0.715  -0.663
202   L        -0.537  -0.523  -0.574  -0.603  -0.584  -0.659  -0.578  -0.558  -0.598
203   S        -1.567  -1.551  -1.472  -1.503  -1.495  -1.373  -1.230  -1.212  -1.089
204   T        -1.438  -1.505  -1.489  -1.207  -1.334  -1.384  -1.099  -1.162  -1.101
205   F        -1.438  -1.505  -1.489  -1.122  -1.252  -1.237  -1.099  -1.162  -1.101
206   F         0.409   0.443   0.149   0.496   0.545   0.162   0.465   0.510   0.057
207   K        -0.751  -0.779  -0.666  -0.656  -0.679  -0.538  -0.839  -0.858  -0.715
208   T        -0.064  -0.094  -0.042  -0.252  -0.289  -0.232  -0.317  -0.329  -0.254
209   M         0.409   0.553   0.161   0.487   0.671   0.163   0.465   0.674   0.076
210   I        -0.420  -0.441  -0.558  -0.424  -0.457  -0.674  -0.394  -0.427  -0.572
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   D        -1.567  -1.520  -1.482  -1.396  -1.302  -1.239  -1.230  -1.186  -1.097
221   S        -0.880  -0.792  -0.963  -0.678  -0.561  -0.816  -0.708  -0.610  -0.781
222   G        -0.621  -0.560  -0.593  -0.563  -0.491  -0.512  -0.708  -0.643  -0.634
223   N        -1.567  -1.533  -1.471  -1.483  -1.423  -1.362  -1.230  -1.194  -1.088
224   K        -1.094  -1.117  -1.110  -1.144  -1.175  -1.165  -0.969  -0.994  -0.939
225   N        -1.094  -0.982  -1.079  -0.997  -0.846  -0.954  -0.969  -0.873  -0.910
226   C        -0.064   0.013  -0.021   0.048   0.154   0.130  -0.317  -0.196  -0.221
227   A         0.083   0.233   0.039   0.265   0.486   0.184  -0.057   0.171  -0.122
228   L         1.120   1.012   0.917   1.103   0.969   0.828   1.247   1.063   0.857
229   V         0.493   0.515   0.648   0.244   0.285   0.479   0.074   0.105   0.301
230   L        -0.621  -0.591  -0.615  -0.702  -0.665  -0.655  -0.708  -0.676  -0.658
231   S         1.120   1.070   0.929   1.202   1.145   0.954   1.247   1.163   0.880
232   E         1.867   1.885   2.013   1.696   1.718   1.933   2.159   2.192   2.435
233   R         1.867   1.885   2.013   2.064   2.089   2.302   2.159   2.192   2.435
234   L         0.409   0.492   0.136   0.496   0.604   0.143   0.465   0.585   0.037
235   I         1.867   1.885   2.013   1.914   1.948   2.152   2.159   2.192   2.435
236   N         1.867   1.885   2.013   1.969   2.004   2.206   2.159   2.192   2.435
237   M         1.867   1.885   2.013   2.097   2.124   2.335   2.159   2.192   2.435
238   P         1.867   1.885   2.013   2.049   2.072   2.287   2.159   2.192   2.435
239   P        -0.064  -0.094  -0.042  -0.068  -0.087  -0.006  -0.317  -0.329  -0.254
240   E         0.753   0.706   0.728   0.558   0.478   0.513   0.595   0.495   0.472
241   V         1.867   1.885   2.013   1.919   1.955   2.157   2.159   2.192   2.435
242   V         0.556   0.536   0.651   0.372   0.329   0.487   0.204   0.149   0.309
243   P         1.120   1.219   0.948   1.404   1.521   1.187   1.247   1.403   0.918
244   P         1.867   1.885   2.013   2.049   2.072   2.287   2.159   2.192   2.435
245   L         0.556   0.641   0.727   0.450   0.625   0.727   0.204   0.366   0.471
246   Y         1.120   1.012   0.917   1.452   1.325   1.224   1.247   1.063   0.857
247   K        -0.537  -0.476  -0.585  -0.497  -0.441  -0.540  -0.578  -0.537  -0.618
248   I         0.556   0.641   0.727   0.528   0.691   0.800   0.204   0.366   0.471
249   T        -0.064  -0.094  -0.042  -0.200  -0.212  -0.117  -0.317  -0.329  -0.254
250   L         0.409   0.384   0.132   0.487   0.446   0.119   0.465   0.416   0.030
251   E         0.409   0.395   0.138   0.379   0.349  -0.016   0.465   0.441   0.039
252   D         0.556   0.641   0.727   0.060   0.216   0.331   0.204   0.366   0.471
253   V        -1.094  -1.093  -1.086  -0.809  -0.799  -0.800  -0.969  -0.960  -0.914
254   A        -1.224  -1.159  -1.110  -1.189  -1.089  -1.040  -1.099  -1.036  -0.941
255   T        -1.226  -1.234  -1.142  -1.258  -1.266  -1.136  -1.085  -1.092  -0.967
256   A         1.867   1.885   2.013   1.983   2.006   2.221   2.159   2.192   2.435
257   L        -1.205  -1.220  -1.138  -1.404  -1.423  -1.278  -1.075  -1.086  -0.964
258   G        -0.271  -0.208  -0.124  -0.514  -0.437  -0.299  -0.565  -0.476  -0.373
259   D        -0.271  -0.245  -0.129  -0.682  -0.653  -0.491  -0.565  -0.530  -0.379
260   D        -1.205  -1.220  -1.138  -1.101  -1.136  -1.005  -1.075  -1.086  -0.964
261   K         0.514   0.592   0.697   0.042   0.186   0.334   0.116   0.266   0.407
262   H        -1.094  -1.011  -1.041  -0.876  -0.763  -0.817  -0.969  -0.879  -0.874
263   Y         0.409   0.452   0.152   0.787   0.840   0.434   0.465   0.523   0.061
264   D        -0.064  -0.098  -0.056  -0.469  -0.522  -0.435  -0.317  -0.359  -0.286
265   F         1.867   1.885   2.013   1.969   1.999   2.206   2.159   2.192   2.435
266   -         0.533   0.526   0.652   0.219   0.207   0.404   0.157   0.128   0.310
267   -         0.533   0.526   0.652   0.592   0.575   0.770   0.157   0.128   0.310
268   Y         0.556   0.579   0.673   0.526   0.560   0.684   0.204   0.238   0.355
269   I         0.409   0.567   0.165   0.455   0.665   0.111   0.465   0.694   0.081
270   I        -0.064  -0.103  -0.055  -0.197  -0.249  -0.192  -0.317  -0.367  -0.286
271   V        -0.194  -0.188  -0.113  -0.379  -0.380  -0.309  -0.448  -0.447  -0.355
272   T         1.120   1.209   0.946   1.207   1.319   0.992   1.247   1.388   0.915
273   R         0.753   0.769   0.745   0.832   0.853   0.754   0.595   0.617   0.509
274   K        -0.751  -0.797  -0.690  -0.836  -0.874  -0.713  -0.839  -0.881  -0.739
275   Y         1.120   1.086   0.931   1.413   1.371   1.162   1.247   1.188   0.884
276   -        -0.773  -0.722  -0.673  -0.746  -0.668  -0.627  -0.844  -0.786  -0.715
277   E         0.753   0.811   0.786   0.460   0.550   0.474   0.595   0.698   0.593
278   V         0.409   0.317   0.117   0.624   0.509   0.205   0.465   0.327   0.007
279   N        -0.621  -0.541  -0.619  -0.822  -0.732  -0.857  -0.708  -0.613  -0.657
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   F        -1.094  -1.088  -1.107  -1.007  -1.028  -1.063  -0.969  -0.969  -0.937
290   D        -0.278  -0.279  -0.144  -0.727  -0.722  -0.520  -0.578  -0.581  -0.401
291   T        -1.224  -1.152  -1.117  -1.219  -1.153  -1.093  -1.099  -1.031  -0.947
292   D        -0.261  -0.241  -0.502  -0.176  -0.153  -0.498  -0.187  -0.164  -0.500
293   D        -0.621  -0.657  -0.597  -0.904  -0.940  -0.821  -0.708  -0.740  -0.639
294   D        -0.751  -0.719  -0.667  -1.014  -1.008  -0.870  -0.839  -0.806  -0.716
295   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   N        -0.537  -0.451  -0.554  -0.789  -0.675  -0.836  -0.578  -0.477  -0.582
302   K        -1.911  -1.893  -1.786  -1.720  -1.694  -1.544  -1.360  -1.343  -1.202
303   N        -1.567  -1.478  -1.457  -1.385  -1.265  -1.235  -1.230  -1.154  -1.078
304   K        -1.911  -1.864  -1.779  -1.571  -1.498  -1.384  -1.360  -1.320  -1.197
305   D        -0.537  -0.410  -0.577  -0.643  -0.455  -0.731  -0.578  -0.428  -0.610
306   E        -1.911  -1.817  -1.790  -1.724  -1.580  -1.553  -1.360  -1.284  -1.205
307   R        -1.094  -1.107  -1.089  -0.994  -1.027  -0.979  -0.969  -0.972  -0.917
308   S        -1.094  -1.098  -1.086  -1.073  -1.049  -1.031  -0.969  -0.963  -0.914
309   K         0.409   0.370   0.128   0.484   0.416   0.071   0.465   0.397   0.023
310   K         0.409   0.251   0.096   0.446   0.217  -0.062   0.465   0.227  -0.027
311   R        -1.094  -1.024  -1.043  -1.010  -0.908  -0.942  -0.969  -0.885  -0.870
312   V        -0.664  -0.755  -0.684  -0.606  -0.737  -0.646  -0.735  -0.830  -0.730
313   K        -1.205  -1.178  -1.118  -0.984  -0.941  -0.876  -1.075  -1.045  -0.946
314   -        -1.226  -1.240  -1.142  -1.005  -1.041  -0.884  -1.085  -1.096  -0.967
315   A        -1.205  -1.173  -1.109  -1.279  -1.229  -1.098  -1.075  -1.044  -0.937
316   D        -1.056  -0.979  -1.080  -0.919  -0.830  -1.059  -0.905  -0.826  -0.906
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   E         1.120   1.012   0.917   1.062   0.923   0.816   1.247   1.063   0.857
321   V        -0.537  -0.616  -0.613  -0.399  -0.511  -0.522  -0.578  -0.661  -0.646
322   D        -0.261  -0.438  -0.552  -0.132  -0.365  -0.487  -0.187  -0.421  -0.564
323   Y         1.120   1.070   0.929   1.413   1.352   1.159   1.247   1.163   0.880
324   F         1.867   1.885   2.013   1.969   1.999   2.206   2.159   2.192   2.435
325   H         1.867   1.885   2.013   2.167   2.193   2.405   2.159   2.192   2.435
326   E        -0.621  -0.541  -0.619  -0.694  -0.546  -0.628  -0.708  -0.613  -0.657
327   E         1.867   1.885   2.013   1.696   1.718   1.933   2.159   2.192   2.435
328   D         1.867   1.885   2.013   1.709   1.734   1.946   2.159   2.192   2.435
329   R        -0.621  -0.541  -0.619  -0.605  -0.544  -0.573  -0.708  -0.613  -0.657
330   F        -1.094  -1.163  -1.112  -0.974  -1.093  -1.032  -0.969  -1.031  -0.941
331   F        -0.621  -0.694  -0.616  -0.663  -0.732  -0.616  -0.708  -0.774  -0.659
332   E         0.083  -0.021  -0.041  -0.011  -0.165  -0.150  -0.057  -0.227  -0.255
333   K        -0.064  -0.041  -0.053  -0.417  -0.397  -0.403  -0.317  -0.295  -0.282
334   Y        -1.567  -1.533  -1.469  -1.264  -1.210  -1.137  -1.230  -1.196  -1.087
335   -        -0.016   0.042  -0.009   0.046   0.125   0.025  -0.177  -0.093  -0.193
336   -        -1.323  -1.287  -1.159  -1.287  -1.232  -1.058  -1.177  -1.141  -0.983
337   -        -1.323  -1.287  -1.159  -1.196  -1.157  -0.968  -1.177  -1.141  -0.983
338   -        -1.323  -1.287  -1.159  -1.263  -1.208  -1.035  -1.177  -1.141  -0.983
339   -         0.533   0.570   0.667   0.479   0.533   0.670   0.157   0.220   0.342
340   -        -0.773  -0.741  -0.660  -0.835  -0.791  -0.700  -0.844  -0.805  -0.699
341   -         0.875   0.945   0.832   1.076   1.180   0.991   0.824   0.945   0.687
342   -        -1.323  -1.287  -1.159  -1.415  -1.331  -1.187  -1.177  -1.141  -0.983
343   -         0.533   0.600   0.692   0.452   0.568   0.695   0.157   0.282   0.396
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   A        -0.537  -0.616  -0.613  -0.396  -0.503  -0.527  -0.578  -0.661  -0.646
346   K         0.083   0.079   0.014  -0.074  -0.057  -0.191  -0.057  -0.051  -0.162
347   I        -1.567  -1.569  -1.484  -1.391  -1.412  -1.282  -1.230  -1.225  -1.099
348   H        -1.438  -1.505  -1.489  -1.002  -1.148  -1.185  -1.099  -1.162  -1.101
349   F        -0.621  -0.630  -0.620  -0.547  -0.576  -0.560  -0.708  -0.715  -0.663
350   E        -0.621  -0.699  -0.600  -0.958  -1.058  -0.901  -0.708  -0.779  -0.642
351   S        -1.224  -1.178  -1.123  -1.066  -1.002  -0.888  -1.099  -1.052  -0.951
352   E         0.556   0.641   0.727   0.065   0.224   0.336   0.204   0.366   0.471
353   A         0.556   0.592   0.678   0.347   0.402   0.524   0.204   0.265   0.366
354   K        -0.064  -0.069  -0.032  -0.158  -0.153  -0.082  -0.317  -0.307  -0.251
355   K         0.556   0.641   0.727   0.440   0.609   0.714   0.204   0.366   0.471
356   G        -0.278  -0.279  -0.144  -0.338  -0.355  -0.157  -0.578  -0.581  -0.401
357   V         0.083   0.235   0.036   0.105   0.350   0.021  -0.057   0.173  -0.127
358   I        -0.278  -0.221  -0.118  -0.341  -0.235  -0.088  -0.578  -0.500  -0.362
359   S        -1.094  -0.948  -1.051  -1.282  -1.099  -1.205  -0.969  -0.825  -0.883
360   -        -0.016  -0.083  -0.056   0.091  -0.042  -0.042  -0.177  -0.284  -0.265
361   -         1.867   1.885   2.013   2.065   2.086   2.303   2.159   2.192   2.435
362   -         0.875   0.807   0.807   0.930   0.823   0.799   0.824   0.691   0.637
363   -        -0.224  -0.194  -0.115  -0.587  -0.530  -0.409  -0.510  -0.468  -0.360
364   -         0.875   0.807   0.807   1.003   0.894   0.860   0.824   0.691   0.637
365   -         0.533   0.600   0.692   0.346   0.481   0.592   0.157   0.282   0.396
366   -         0.533   0.600   0.692   0.364   0.498   0.611   0.157   0.282   0.396
367   S        -0.261  -0.438  -0.552  -0.068  -0.324  -0.505  -0.187  -0.421  -0.564
368   Y        -0.064  -0.094  -0.042  -0.161  -0.181  -0.083  -0.317  -0.329  -0.254
369   M        -0.064  -0.066  -0.033  -0.049  -0.029  -0.005  -0.317  -0.302  -0.251
370   I         0.083   0.233   0.039  -0.036   0.195  -0.098  -0.057   0.171  -0.122
371   L        -0.537  -0.552  -0.562  -0.487  -0.469  -0.495  -0.578  -0.579  -0.581
372   D        -0.261  -0.438  -0.552  -0.281  -0.561  -0.767  -0.187  -0.421  -0.564
373   H        -0.751  -0.775  -0.687  -0.632  -0.680  -0.571  -0.839  -0.861  -0.736
374   E        -1.567  -1.557  -1.456  -1.673  -1.655  -1.497  -1.230  -1.216  -1.078
375   G        -1.567  -1.520  -1.482  -1.453  -1.405  -1.353  -1.230  -1.186  -1.097
376   L         0.753   0.669   0.712   0.593   0.454   0.499   0.595   0.421   0.438
377   V        -1.224  -1.177  -1.124  -1.300  -1.252  -1.184  -1.099  -1.050  -0.952
378   K        -0.880  -0.991  -1.048  -0.739  -0.889  -1.005  -0.708  -0.837  -0.872
379   S        -0.261  -0.438  -0.552  -0.106  -0.367  -0.576  -0.187  -0.421  -0.564
380   I         0.493   0.531   0.656   0.244   0.319   0.497   0.074   0.138   0.319
381   D        -1.911  -1.859  -1.789  -1.740  -1.664  -1.613  -1.360  -1.317  -1.204
382   E        -1.094  -1.092  -1.079  -1.255  -1.261  -1.222  -0.969  -0.974  -0.910
383   L        -0.621  -0.622  -0.619  -0.600  -0.599  -0.581  -0.708  -0.707  -0.662
384   E        -0.261  -0.346  -0.513  -0.215  -0.330  -0.569  -0.187  -0.307  -0.514
385   T        -1.567  -1.549  -1.463  -1.497  -1.526  -1.352  -1.230  -1.210  -1.083
386   E        -1.438  -1.445  -1.435  -1.275  -1.267  -1.241  -1.099  -1.108  -1.056
387   I        -0.621  -0.591  -0.615  -0.562  -0.515  -0.524  -0.708  -0.676  -0.658
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   S        -0.751  -0.707  -0.664  -0.787  -0.736  -0.666  -0.839  -0.799  -0.710
390   T        -0.278  -0.281  -0.145  -0.295  -0.310  -0.106  -0.578  -0.583  -0.403
391   W        -0.595  -0.703  -0.681  -0.157  -0.359  -0.356  -0.621  -0.765  -0.724
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06338
Output conservation file - output/Q06338
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
