1     M         1.123   1.125   1.140   1.408   1.409   1.426   1.167   1.168   1.185
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    D         1.123   1.125   1.140   1.272   1.274   1.293   1.167   1.168   1.185
20    V        -0.354  -0.331  -0.400  -0.799  -0.764  -0.858  -0.469  -0.434  -0.535
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -         1.123   1.125   1.140   1.115   1.117   1.140   1.167   1.168   1.185
24    -        -0.485  -0.483  -0.450  -0.826  -0.823  -0.758  -0.674  -0.670  -0.613
25    -        -0.485  -0.483  -0.450  -0.622  -0.619  -0.559  -0.674  -0.670  -0.613
26    -        -0.485  -0.483  -0.450  -0.436  -0.432  -0.376  -0.674  -0.670  -0.613
27    L        -1.426  -1.421  -1.380  -1.679  -1.670  -1.592  -1.287  -1.281  -1.212
28    L        -0.354  -0.383  -0.413  -0.592  -0.625  -0.620  -0.469  -0.514  -0.556
29    S        -0.354  -0.338  -0.400  -0.308  -0.283  -0.370  -0.469  -0.445  -0.535
30    L        -0.354  -0.338  -0.400  -0.809  -0.784  -0.870  -0.469  -0.445  -0.535
31    P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
32    Q        -1.426  -1.421  -1.380  -1.175  -1.168  -1.099  -1.287  -1.281  -1.212
33    P        -0.354  -0.383  -0.413  -0.122  -0.167  -0.207  -0.469  -0.514  -0.556
34    E        -1.426  -1.421  -1.380  -1.090  -1.086  -1.016  -1.287  -1.281  -1.212
35    L        -1.426  -1.421  -1.380  -1.557  -1.528  -1.473  -1.287  -1.281  -1.212
36    F        -0.354  -0.383  -0.413  -0.608  -0.669  -0.753  -0.469  -0.514  -0.556
37    K        -1.426  -1.421  -1.380  -1.186  -1.177  -1.110  -1.287  -1.281  -1.212
38    T        -1.426  -1.421  -1.380  -1.108  -1.097  -1.034  -1.287  -1.281  -1.212
39    T        -1.426  -1.421  -1.380  -1.239  -1.233  -1.162  -1.287  -1.281  -1.212
40    V         1.123   1.125   1.140   1.002   1.005   1.030   1.167   1.168   1.185
41    I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
42    P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
43    F        -0.354  -0.383  -0.413  -0.396  -0.441  -0.484  -0.469  -0.514  -0.556
44    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
45    A        -1.426  -1.421  -1.380  -1.050  -1.041  -0.977  -1.287  -1.281  -1.212
46    N        -1.426  -1.421  -1.380  -1.243  -1.242  -1.165  -1.287  -1.281  -1.212
47    R        -1.426  -1.421  -1.380  -1.160  -1.158  -1.084  -1.287  -1.281  -1.212
48    N        -0.354  -0.383  -0.413  -0.204  -0.251  -0.295  -0.469  -0.514  -0.556
49    I        -0.354  -0.383  -0.413  -0.390  -0.429  -0.451  -0.469  -0.514  -0.556
50    I        -0.354  -0.338  -0.400  -0.555  -0.527  -0.633  -0.469  -0.445  -0.535
51    K        -0.354  -0.383  -0.413  -0.253  -0.297  -0.346  -0.469  -0.514  -0.556
52    S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
53    E        -0.354  -0.383  -0.413  -0.109  -0.160  -0.219  -0.469  -0.514  -0.556
54    A        -0.354  -0.383  -0.413  -0.319  -0.375  -0.445  -0.469  -0.514  -0.556
55    I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
56    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
57    S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
58    N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
59    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
60    H         1.123   1.125   1.140   1.377   1.379   1.396   1.167   1.168   1.185
61    S        -0.354  -0.383  -0.413  -0.322  -0.367  -0.408  -0.469  -0.514  -0.556
62    I        -0.354  -0.383  -0.413  -0.555  -0.606  -0.658  -0.469  -0.514  -0.556
63    F        -1.426  -1.421  -1.380  -1.780  -1.784  -1.690  -1.287  -1.281  -1.212
64    Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
65    V        -0.354  -0.383  -0.413  -0.545  -0.598  -0.652  -0.469  -0.514  -0.556
66    A         1.123   1.125   1.140   1.234   1.237   1.256   1.167   1.168   1.185
67    I        -1.426  -1.421  -1.380  -1.822  -1.809  -1.731  -1.287  -1.281  -1.212
68    F        -0.354  -0.331  -0.400  -0.247  -0.206  -0.341  -0.469  -0.434  -0.535
69    Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
70    H        -0.354  -0.338  -0.400  -0.040  -0.015  -0.116  -0.469  -0.445  -0.535
71    I        -1.426  -1.421  -1.380  -1.228  -1.218  -1.151  -1.287  -1.281  -1.212
72    W        -0.354  -0.383  -0.413  -0.334  -0.401  -0.501  -0.469  -0.514  -0.556
73    F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
74    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
75    F        -1.426  -1.421  -1.380  -1.605  -1.612  -1.519  -1.287  -1.281  -1.212
76    G        -1.426  -1.421  -1.380  -1.224  -1.222  -1.147  -1.287  -1.281  -1.212
77    K        -1.426  -1.421  -1.380  -1.087  -1.076  -1.013  -1.287  -1.281  -1.212
78    W        -0.354  -0.383  -0.413  -0.067  -0.113  -0.163  -0.469  -0.514  -0.556
79    I        -1.426  -1.421  -1.380  -1.822  -1.809  -1.731  -1.287  -1.281  -1.212
80    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
81    F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
82    P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
83    H        -0.354  -0.331  -0.400  -0.122  -0.090  -0.187  -0.469  -0.434  -0.535
84    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
85    V        -1.426  -1.421  -1.380  -1.320  -1.308  -1.241  -1.287  -1.281  -1.212
86    K        -0.354  -0.383  -0.413  -0.311  -0.359  -0.419  -0.469  -0.514  -0.556
87    W        -0.354  -0.383  -0.413  -0.136  -0.188  -0.250  -0.469  -0.514  -0.556
88    K        -0.354  -0.331  -0.400  -0.139  -0.101  -0.226  -0.469  -0.434  -0.535
89    L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
90    D        -0.354  -0.331  -0.400  -0.308  -0.273  -0.370  -0.469  -0.434  -0.535
91    Y        -1.426  -1.421  -1.380  -1.065  -1.056  -0.991  -1.287  -1.281  -1.212
92    D        -0.354  -0.338  -0.400  -0.235  -0.208  -0.324  -0.469  -0.445  -0.535
93    Q        -1.426  -1.421  -1.380  -1.130  -1.124  -1.055  -1.287  -1.281  -1.212
94    K        -0.485  -0.483  -0.450  -0.412  -0.408  -0.353  -0.674  -0.670  -0.613
95    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    V        -0.354  -0.383  -0.413  -0.423  -0.466  -0.499  -0.469  -0.514  -0.556
98    K        -1.426  -1.421  -1.380  -1.190  -1.181  -1.114  -1.287  -1.281  -1.212
99    K        -0.354  -0.338  -0.400  -0.261  -0.235  -0.334  -0.469  -0.445  -0.535
100   D         1.123   1.125   1.140   1.272   1.274   1.293   1.167   1.168   1.185
101   E        -0.354  -0.383  -0.413  -0.056  -0.103  -0.154  -0.469  -0.514  -0.556
102   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   A        -0.485  -0.483  -0.450  -0.343  -0.340  -0.286  -0.674  -0.670  -0.613
110   Q        -0.485  -0.483  -0.450  -0.450  -0.446  -0.390  -0.674  -0.670  -0.613
111   H        -0.485  -0.483  -0.450  -0.462  -0.459  -0.402  -0.674  -0.670  -0.613
112   Y        -0.485  -0.483  -0.450  -0.520  -0.517  -0.459  -0.674  -0.670  -0.613
113   K        -0.485  -0.483  -0.450  -0.412  -0.408  -0.353  -0.674  -0.670  -0.613
114   K         1.123   1.125   1.140   1.190   1.195   1.213   1.167   1.168   1.185
115   K        -0.354  -0.383  -0.413  -0.207  -0.248  -0.289  -0.469  -0.514  -0.556
116   Y        -1.426  -1.421  -1.380  -1.130  -1.118  -1.055  -1.287  -1.281  -1.212
117   T        -1.426  -1.421  -1.380  -1.209  -1.200  -1.132  -1.287  -1.281  -1.212
118   S        -1.426  -1.421  -1.380  -1.262  -1.248  -1.184  -1.287  -1.281  -1.212
119   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
120   I        -1.426  -1.421  -1.380  -1.490  -1.487  -1.407  -1.287  -1.281  -1.212
121   N        -0.354  -0.338  -0.400  -0.340  -0.313  -0.437  -0.469  -0.445  -0.535
122   Q        -0.354  -0.338  -0.400  -0.064  -0.041  -0.136  -0.469  -0.445  -0.535
123   S        -0.354  -0.338  -0.400  -0.325  -0.300  -0.391  -0.469  -0.445  -0.535
124   S        -0.354  -0.331  -0.400  -0.270  -0.231  -0.356  -0.469  -0.434  -0.535
125   V        -0.354  -0.338  -0.400  -0.545  -0.518  -0.627  -0.469  -0.445  -0.535
126   H        -0.354  -0.383  -0.413  -0.040  -0.087  -0.139  -0.469  -0.514  -0.556
127   L        -0.354  -0.338  -0.400  -0.769  -0.744  -0.822  -0.469  -0.445  -0.535
128   I        -0.354  -0.331  -0.400  -0.545  -0.506  -0.627  -0.469  -0.434  -0.535
129   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
130   L        -1.426  -1.421  -1.380  -1.528  -1.499  -1.444  -1.287  -1.281  -1.212
131   L        -0.354  -0.383  -0.413  -0.809  -0.858  -0.891  -0.469  -0.514  -0.556
132   Q         1.123   1.125   1.140   1.340   1.342   1.360   1.167   1.168   1.185
133   S        -0.354  -0.338  -0.400  -0.322  -0.297  -0.388  -0.469  -0.445  -0.535
134   I        -0.354  -0.331  -0.400  -0.809  -0.773  -0.870  -0.469  -0.434  -0.535
135   V        -0.354  -0.383  -0.413  -0.545  -0.598  -0.652  -0.469  -0.514  -0.556
136   V         1.123   1.125   1.140   1.002   1.005   1.030   1.167   1.168   1.185
137   L        -0.354  -0.338  -0.400  -0.799  -0.775  -0.858  -0.469  -0.445  -0.535
138   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
139   Y        -0.354  -0.331  -0.400  -0.707  -0.677  -0.747  -0.469  -0.434  -0.535
140   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
141   L        -0.354  -0.383  -0.413  -0.769  -0.814  -0.841  -0.469  -0.514  -0.556
142   K        -1.426  -1.421  -1.380  -1.285  -1.267  -1.207  -1.287  -1.281  -1.212
143   F        -0.354  -0.383  -0.413  -0.372  -0.414  -0.454  -0.469  -0.514  -0.556
144   L        -0.354  -0.383  -0.413  -0.809  -0.858  -0.891  -0.469  -0.514  -0.556
145   L        -1.426  -1.421  -1.380  -1.356  -1.341  -1.276  -1.287  -1.281  -1.212
146   D        -0.354  -0.383  -0.413  -0.204  -0.255  -0.311  -0.469  -0.514  -0.556
147   P        -1.426  -1.421  -1.380  -1.145  -1.142  -1.070  -1.287  -1.281  -1.212
148   K        -1.426  -1.421  -1.380  -1.197  -1.190  -1.121  -1.287  -1.281  -1.212
149   A        -1.426  -1.421  -1.380  -1.138  -1.124  -1.063  -1.287  -1.281  -1.212
150   S        -1.426  -1.421  -1.380  -1.281  -1.271  -1.203  -1.287  -1.281  -1.212
151   A        -1.426  -1.421  -1.380  -1.239  -1.230  -1.162  -1.287  -1.281  -1.212
152   E        -1.426  -1.421  -1.380  -1.097  -1.093  -1.023  -1.287  -1.281  -1.212
153   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   Y         1.123   1.125   1.140   1.217   1.219   1.240   1.167   1.168   1.185
155   Q        -1.426  -1.421  -1.380  -1.396  -1.412  -1.315  -1.287  -1.281  -1.212
156   T        -0.354  -0.383  -0.413  -0.215  -0.264  -0.316  -0.469  -0.514  -0.556
157   S        -0.354  -0.338  -0.400  -0.432  -0.404  -0.520  -0.469  -0.445  -0.535
158   H        -0.354  -0.338  -0.400  -0.092  -0.067  -0.179  -0.469  -0.445  -0.535
159   S        -1.426  -1.421  -1.380  -1.235  -1.224  -1.158  -1.287  -1.281  -1.212
160   R         1.123   1.125   1.140   1.340   1.342   1.360   1.167   1.168   1.185
161   V        -0.354  -0.331  -0.400  -0.555  -0.516  -0.633  -0.469  -0.434  -0.535
162   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
163   T        -0.354  -0.331  -0.400  -0.167  -0.131  -0.246  -0.469  -0.434  -0.535
164   E        -1.426  -1.421  -1.380  -0.951  -0.944  -0.880  -1.287  -1.281  -1.212
165   N        -1.426  -1.421  -1.380  -1.243  -1.233  -1.165  -1.287  -1.281  -1.212
166   R        -0.354  -0.383  -0.413  -0.106  -0.155  -0.210  -0.469  -0.514  -0.556
167   D        -0.354  -0.383  -0.413  -0.204  -0.255  -0.311  -0.469  -0.514  -0.556
168   T        -0.354  -0.383  -0.413  -0.215  -0.264  -0.316  -0.469  -0.514  -0.556
169   Q        -1.426  -1.421  -1.380  -1.182  -1.189  -1.106  -1.287  -1.281  -1.212
170   V        -1.426  -1.421  -1.380  -1.511  -1.494  -1.427  -1.287  -1.281  -1.212
171   I        -0.354  -0.383  -0.413  -0.555  -0.606  -0.658  -0.469  -0.514  -0.556
172   C        -0.354  -0.338  -0.400  -0.029  -0.002  -0.119  -0.469  -0.445  -0.535
173   I        -0.354  -0.331  -0.400  -0.545  -0.506  -0.627  -0.469  -0.434  -0.535
174   F        -0.354  -0.338  -0.400  -0.396  -0.369  -0.463  -0.469  -0.445  -0.535
175   A         1.123   1.125   1.140   1.234   1.237   1.256   1.167   1.168   1.185
176   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
177   G         1.123   1.125   1.140   1.284   1.286   1.305   1.167   1.168   1.185
178   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
179   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
180   V        -0.354  -0.383  -0.413  -0.665  -0.728  -0.805  -0.469  -0.514  -0.556
181   W         1.123   1.125   1.140   1.346   1.349   1.366   1.167   1.168   1.185
182   D         1.123   1.125   1.140   1.272   1.274   1.293   1.167   1.168   1.185
183   I        -0.354  -0.338  -0.400  -0.555  -0.527  -0.633  -0.469  -0.445  -0.535
184   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
185   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
186   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
187   T        -1.426  -1.421  -1.380  -1.640  -1.650  -1.553  -1.287  -1.281  -1.212
188   M        -1.426  -1.421  -1.380  -1.523  -1.523  -1.440  -1.287  -1.281  -1.212
189   Y        -0.354  -0.338  -0.400  -0.196  -0.174  -0.254  -0.469  -0.445  -0.535
190   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
191   T         1.123   1.125   1.140   1.240   1.243   1.263   1.167   1.168   1.185
192   F        -0.354  -0.331  -0.400  -0.769  -0.734  -0.822  -0.469  -0.434  -0.535
193   P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
194   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
195   V         1.123   1.125   1.140   1.002   1.005   1.030   1.167   1.168   1.185
196   V        -0.354  -0.331  -0.400  -0.799  -0.764  -0.858  -0.469  -0.434  -0.535
197   H         1.123   1.125   1.140   1.377   1.379   1.396   1.167   1.168   1.185
198   G         1.123   1.125   1.140   1.284   1.286   1.305   1.167   1.168   1.185
199   I        -0.354  -0.383  -0.413  -0.685  -0.747  -0.823  -0.469  -0.514  -0.556
200   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
201   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
202   T         1.123   1.125   1.140   1.240   1.243   1.263   1.167   1.168   1.185
203   V         1.123   1.125   1.140   1.002   1.005   1.030   1.167   1.168   1.185
204   V         1.123   1.125   1.140   1.002   1.005   1.030   1.167   1.168   1.185
205   F        -0.354  -0.383  -0.413  -0.396  -0.441  -0.484  -0.469  -0.514  -0.556
206   C        -1.426  -1.421  -1.380  -1.061  -1.059  -0.988  -1.287  -1.281  -1.212
207   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
208   G         1.123   1.125   1.140   1.284   1.286   1.305   1.167   1.168   1.185
209   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
210   K         1.123   1.125   1.140   1.190   1.195   1.213   1.167   1.168   1.185
211   P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
212   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
213   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
214   Q        -0.354  -0.383  -0.413  -0.125  -0.176  -0.234  -0.469  -0.514  -0.556
215   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
216   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
217   A         1.123   1.125   1.140   1.234   1.237   1.256   1.167   1.168   1.185
218   P        -0.354  -0.383  -0.413  -0.164  -0.212  -0.260  -0.469  -0.514  -0.556
219   V        -0.354  -0.383  -0.413  -0.545  -0.598  -0.652  -0.469  -0.514  -0.556
220   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
221   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
222   M         1.123   1.125   1.140   1.408   1.409   1.426   1.167   1.168   1.185
223   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
224   E         1.123   1.125   1.140   1.359   1.361   1.378   1.167   1.168   1.185
225   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
226   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
227   N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
228   P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
229   S        -0.354  -0.331  -0.400  -0.429  -0.389  -0.502  -0.469  -0.434  -0.535
230   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
231   N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
232   F        -1.426  -1.421  -1.380  -1.780  -1.768  -1.690  -1.287  -1.281  -1.212
233   R         1.123   1.125   1.140   1.340   1.342   1.360   1.167   1.168   1.185
234   W         1.123   1.125   1.140   1.346   1.349   1.366   1.167   1.168   1.185
235   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
236   G         1.123   1.125   1.140   1.284   1.286   1.305   1.167   1.168   1.185
237   I        -0.354  -0.338  -0.400  -0.685  -0.653  -0.790  -0.469  -0.445  -0.535
238   K         1.123   1.125   1.140   1.190   1.195   1.213   1.167   1.168   1.185
239   F        -0.354  -0.331  -0.400  -0.340  -0.301  -0.427  -0.469  -0.434  -0.535
240   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
241   P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
242   Q        -0.354  -0.338  -0.400  -0.117  -0.091  -0.199  -0.469  -0.445  -0.535
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   K        -1.426  -1.421  -1.380  -1.036  -1.023  -0.963  -1.287  -1.281  -1.212
252   S        -1.426  -1.421  -1.380  -1.266  -1.257  -1.188  -1.287  -1.281  -1.212
253   K        -0.354  -0.338  -0.400  -0.207  -0.181  -0.269  -0.469  -0.445  -0.535
254   F        -0.354  -0.331  -0.400  -0.508  -0.470  -0.582  -0.469  -0.434  -0.535
255   C         1.123   1.125   1.140   1.438   1.440   1.456   1.167   1.168   1.185
256   S        -0.354  -0.383  -0.413  -0.331  -0.377  -0.419  -0.469  -0.514  -0.556
257   L        -1.426  -1.421  -1.380  -1.822  -1.807  -1.731  -1.287  -1.281  -1.212
258   L        -1.426  -1.421  -1.380  -1.657  -1.648  -1.570  -1.287  -1.281  -1.212
259   L        -0.354  -0.383  -0.413  -0.627  -0.663  -0.663  -0.469  -0.514  -0.556
260   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
261   L        -1.426  -1.421  -1.380  -1.822  -1.807  -1.731  -1.287  -1.281  -1.212
262   N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
263   N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
264   L        -0.354  -0.383  -0.413  -0.799  -0.848  -0.878  -0.469  -0.514  -0.556
265   T        -1.426  -1.421  -1.380  -1.640  -1.634  -1.553  -1.287  -1.281  -1.212
266   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
267   M        -1.426  -1.421  -1.380  -1.536  -1.536  -1.452  -1.287  -1.281  -1.212
268   V        -1.426  -1.421  -1.380  -1.822  -1.826  -1.731  -1.287  -1.281  -1.212
269   V        -1.426  -1.421  -1.380  -1.596  -1.588  -1.511  -1.287  -1.281  -1.212
270   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
271   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
272   A        -1.426  -1.421  -1.380  -1.570  -1.582  -1.485  -1.287  -1.281  -1.212
273   A         1.123   1.125   1.140   1.234   1.237   1.256   1.167   1.168   1.185
274   R         1.123   1.125   1.140   1.340   1.342   1.360   1.167   1.168   1.185
275   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
276   A        -0.354  -0.383  -0.413  -0.122  -0.163  -0.197  -0.469  -0.514  -0.556
277   W         1.123   1.125   1.140   1.346   1.349   1.366   1.167   1.168   1.185
278   G         1.123   1.125   1.140   1.284   1.286   1.305   1.167   1.168   1.185
279   W        -0.354  -0.383  -0.413  -0.190  -0.243  -0.318  -0.469  -0.514  -0.556
280   F        -0.354  -0.331  -0.400  -0.340  -0.301  -0.427  -0.469  -0.434  -0.535
281   Q         1.123   1.125   1.140   1.340   1.342   1.360   1.167   1.168   1.185
282   I        -0.354  -0.383  -0.413  -0.527  -0.574  -0.622  -0.469  -0.514  -0.556
283   G        -0.354  -0.383  -0.413  -0.193  -0.244  -0.301  -0.469  -0.514  -0.556
284   K        -0.354  -0.383  -0.413  -0.207  -0.248  -0.289  -0.469  -0.514  -0.556
285   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
286   C        -0.354  -0.338  -0.400  -0.029  -0.002  -0.119  -0.469  -0.445  -0.535
287   Y        -1.426  -1.421  -1.380  -1.145  -1.139  -1.070  -1.287  -1.281  -1.212
288   D         1.123   1.125   1.140   1.272   1.274   1.293   1.167   1.168   1.185
289   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
290   Y         1.123   1.125   1.140   1.183   1.184   1.207   1.167   1.168   1.185
291   Q        -1.426  -1.421  -1.380  -1.127  -1.124  -1.052  -1.287  -1.281  -1.212
292   V        -0.354  -0.383  -0.413  -0.545  -0.598  -0.652  -0.469  -0.514  -0.556
293   R        -0.354  -0.338  -0.400  -0.056  -0.033  -0.126  -0.469  -0.445  -0.535
294   N        -0.354  -0.338  -0.400  -0.224  -0.200  -0.298  -0.469  -0.445  -0.535
295   E        -0.354  -0.331  -0.400  -0.125  -0.091  -0.192  -0.469  -0.434  -0.535
296   P         1.123   1.125   1.140   1.265   1.266   1.287   1.167   1.168   1.185
297   G        -1.426  -1.421  -1.380  -1.164  -1.164  -1.088  -1.287  -1.281  -1.212
298   F         1.123   1.125   1.140   1.061   1.067   1.087   1.167   1.168   1.185
299   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
300   V        -1.426  -1.421  -1.380  -1.235  -1.224  -1.158  -1.287  -1.281  -1.212
301   F        -0.354  -0.331  -0.400  -0.769  -0.734  -0.822  -0.469  -0.434  -0.535
302   D        -0.354  -0.383  -0.413  -0.125  -0.169  -0.213  -0.469  -0.514  -0.556
303   T        -0.354  -0.338  -0.400  -0.264  -0.237  -0.351  -0.469  -0.445  -0.535
304   I        -1.426  -1.421  -1.380  -1.412  -1.396  -1.331  -1.287  -1.281  -1.212
305   V        -0.354  -0.331  -0.400  -0.555  -0.516  -0.633  -0.469  -0.434  -0.535
306   I         1.123   1.125   1.140   0.983   0.985   1.011   1.167   1.168   1.185
307   L        -0.354  -0.331  -0.400  -0.665  -0.621  -0.772  -0.469  -0.434  -0.535
308   A        -1.426  -1.421  -1.380  -1.153  -1.146  -1.077  -1.287  -1.281  -1.212
309   G         1.123   1.125   1.140   1.284   1.286   1.305   1.167   1.168   1.185
310   N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
311   F        -0.354  -0.331  -0.400  -0.769  -0.734  -0.822  -0.469  -0.434  -0.535
312   V        -0.354  -0.383  -0.413  -0.545  -0.598  -0.652  -0.469  -0.514  -0.556
313   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
314   D         1.123   1.125   1.140   1.272   1.274   1.293   1.167   1.168   1.185
315   I        -0.354  -0.331  -0.400  -0.545  -0.506  -0.627  -0.469  -0.434  -0.535
316   L         1.123   1.125   1.140   0.725   0.727   0.759   1.167   1.168   1.185
317   N         1.123   1.125   1.140   1.221   1.222   1.244   1.167   1.168   1.185
318   V        -1.426  -1.421  -1.380  -1.644  -1.653  -1.558  -1.287  -1.281  -1.212
319   I        -0.354  -0.383  -0.413  -0.527  -0.574  -0.622  -0.469  -0.514  -0.556
320   W         1.123   1.125   1.140   1.346   1.349   1.366   1.167   1.168   1.185
321   F        -0.354  -0.383  -0.413  -0.608  -0.669  -0.753  -0.469  -0.514  -0.556
322   S        -0.354  -0.338  -0.400  -0.302  -0.278  -0.363  -0.469  -0.445  -0.535
323   T         1.123   1.125   1.140   1.240   1.243   1.263   1.167   1.168   1.185
324   M         1.123   1.125   1.140   1.408   1.409   1.426   1.167   1.168   1.185
325   V        -0.354  -0.331  -0.400  -0.799  -0.764  -0.858  -0.469  -0.434  -0.535
326   S         1.123   1.125   1.140   1.113   1.116   1.138   1.167   1.168   1.185
327   V         1.123   1.125   1.140   1.002   1.005   1.030   1.167   1.168   1.185
328   A         1.123   1.125   1.140   1.234   1.237   1.256   1.167   1.168   1.185
329   A        -1.426  -1.421  -1.380  -1.432  -1.430  -1.351  -1.287  -1.281  -1.212
330   K        -1.426  -1.421  -1.380  -1.156  -1.144  -1.081  -1.287  -1.281  -1.212
331   V        -0.354  -0.383  -0.413  -0.545  -0.598  -0.652  -0.469  -0.514  -0.556
332   L        -0.354  -0.331  -0.400  -0.685  -0.640  -0.790  -0.469  -0.434  -0.535
333   K        -0.354  -0.338  -0.400  -0.253  -0.225  -0.324  -0.469  -0.445  -0.535
334   K         1.123   1.125   1.140   1.190   1.195   1.213   1.167   1.168   1.185
335   G         1.123   1.125   1.140   1.307   1.310   1.328   1.167   1.168   1.185
336   E        -0.485  -0.483  -0.450  -0.312  -0.309  -0.256  -0.674  -0.670  -0.613
337   S        -0.485  -0.483  -0.450  -0.612  -0.608  -0.548  -0.674  -0.670  -0.613
338   V         1.123   1.125   1.140   0.976   0.978   1.004   1.167   1.168   1.185
339   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   K        -0.485  -0.483  -0.450  -0.433  -0.430  -0.374  -0.674  -0.670  -0.613
344   N        -1.426  -1.421  -1.380  -1.156  -1.145  -1.081  -1.287  -1.281  -1.212
345   E        -1.426  -1.421  -1.380  -1.116  -1.108  -1.041  -1.287  -1.281  -1.212
346   Q        -1.426  -1.421  -1.380  -1.127  -1.123  -1.052  -1.287  -1.281  -1.212
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q06107
Output conservation file - output/Q06107
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
