1     M         2.512   2.554   2.654   2.905   2.966   3.135   2.887   2.961   3.139
2     S        -0.269  -0.189  -0.300  -0.123  -0.015  -0.149  -0.290  -0.182  -0.322
3     T        -0.981  -0.990  -0.983  -1.161  -1.183  -1.181  -0.820  -0.825  -0.797
4     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     R        -0.591  -0.578  -0.521  -0.720  -0.693  -0.618  -0.687  -0.670  -0.595
9     K         1.254   1.336   1.293   1.155   1.280   1.208   1.100   1.249   1.125
10    D         0.151   0.113   0.208   0.020  -0.037   0.104  -0.163  -0.210  -0.086
11    D        -0.470  -0.412  -0.425  -0.171  -0.081  -0.098  -0.544  -0.469  -0.481
12    V        -0.470  -0.420  -0.428  -0.405  -0.312  -0.354  -0.544  -0.479  -0.485
13    K        -0.464  -0.437  -0.437  -0.723  -0.700  -0.687  -0.555  -0.522  -0.504
14    L         1.504   1.408   1.410   1.235   1.095   1.068   1.563   1.384   1.357
15    L        -0.269  -0.315  -0.343  -0.501  -0.586  -0.683  -0.290  -0.350  -0.377
16    E         0.248   0.295   0.280  -0.006   0.054   0.034  -0.025   0.043   0.024
17    L         0.570   0.505   0.441   0.302   0.205   0.074   0.504   0.399   0.293
18    L        -0.464  -0.483  -0.432  -0.712  -0.726  -0.652  -0.555  -0.573  -0.500
19    N        -0.464  -0.425  -0.438  -0.368  -0.333  -0.328  -0.555  -0.509  -0.506
20    S         1.504   1.560   1.436   1.560   1.633   1.492   1.563   1.660   1.408
21    I         0.053   0.071   0.141  -0.317  -0.305  -0.217  -0.290  -0.267  -0.176
22    D         0.570   0.494   0.436   0.540   0.423   0.321   0.504   0.382   0.285
23    E        -0.269  -0.311  -0.334  -0.208  -0.280  -0.284  -0.290  -0.344  -0.366
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    Q         0.248   0.193   0.260   0.195   0.092   0.179  -0.025  -0.095  -0.011
27    F         0.570   0.507   0.452   0.944   0.837   0.774   0.504   0.402   0.310
28    L         0.151   0.173   0.206   0.222   0.251   0.280  -0.163  -0.133  -0.087
29    V        -0.470  -0.399  -0.423  -0.602  -0.452  -0.558  -0.544  -0.453  -0.479
30    P        -0.269  -0.309  -0.345   0.222   0.155   0.118  -0.290  -0.342  -0.380
31    Y        -0.269  -0.309  -0.345   0.242   0.177   0.131  -0.290  -0.342  -0.380
32    K        -0.981  -0.996  -0.976  -1.030  -1.014  -1.021  -0.820  -0.832  -0.790
33    K        -0.464  -0.428  -0.424  -0.694  -0.650  -0.654  -0.555  -0.511  -0.492
34    P        -1.090  -1.081  -1.032  -0.792  -0.753  -0.693  -0.926  -0.912  -0.844
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    E        -0.981  -0.986  -0.966  -1.047  -1.075  -1.021  -0.820  -0.822  -0.780
37    D        -0.464  -0.421  -0.426  -0.662  -0.609  -0.603  -0.555  -0.505  -0.493
38    L        -0.269  -0.309  -0.345  -0.299  -0.322  -0.369  -0.290  -0.342  -0.380
39    R        -0.981  -0.940  -0.949  -0.742  -0.693  -0.671  -0.820  -0.771  -0.764
40    K        -0.981  -0.996  -0.976  -0.969  -0.967  -0.952  -0.820  -0.832  -0.790
41    I         1.504   1.563   1.443   1.455   1.543   1.338   1.563   1.664   1.422
42    S        -0.269  -0.311  -0.334  -0.242  -0.335  -0.342  -0.290  -0.344  -0.366
43    S        -0.981  -0.996  -0.976  -1.229  -1.285  -1.252  -0.820  -0.832  -0.790
44    T        -1.498  -1.492  -1.450  -1.305  -1.258  -1.224  -1.085  -1.074  -1.010
45    T         0.570   0.507   0.452   0.760   0.649   0.544   0.504   0.402   0.310
46    K        -0.269  -0.309  -0.345  -0.270  -0.361  -0.388  -0.290  -0.342  -0.380
47    L         0.570   0.632   0.472   0.437   0.534   0.309   0.504   0.600   0.342
48    Q        -0.470  -0.465  -0.458  -0.209  -0.199  -0.199  -0.544  -0.535  -0.521
49    G        -0.464  -0.433  -0.431  -0.250  -0.205  -0.194  -0.555  -0.517  -0.498
50    S        -0.269  -0.309  -0.345  -0.336  -0.428  -0.481  -0.290  -0.342  -0.380
51    T        -0.464  -0.425  -0.438  -0.548  -0.500  -0.513  -0.555  -0.509  -0.506
52    P         1.504   1.560   1.436   1.821   1.908   1.700   1.563   1.660   1.408
53    T         0.570   0.618   0.476   0.450   0.529   0.332   0.504   0.579   0.349
54    K        -0.981  -0.993  -0.964  -1.032  -1.076  -1.002  -0.820  -0.828  -0.779
55    E         1.504   1.408   1.410   1.505   1.375   1.401   1.563   1.384   1.357
56    L         2.512   2.554   2.654   2.229   2.299   2.435   2.887   2.961   3.139
57    D        -0.981  -0.987  -0.959  -1.087  -1.113  -1.066  -0.820  -0.823  -0.773
58    K         1.504   1.408   1.410   1.450   1.304   1.299   1.563   1.384   1.357
59    L         1.504   1.408   1.410   1.306   1.187   1.178   1.563   1.384   1.357
60    A         0.570   0.629   0.484   0.822   0.908   0.669   0.504   0.597   0.361
61    S         0.570   0.494   0.436   0.549   0.436   0.334   0.504   0.382   0.285
62    V         0.570   0.645   0.468   0.366   0.488   0.206   0.504   0.620   0.335
63    L         1.088   1.141   1.158   0.695   0.793   0.759   0.769   0.863   0.845
64    K         0.570   0.507   0.452   0.720   0.643   0.596   0.504   0.402   0.310
65    A         0.570   0.505   0.441   0.900   0.801   0.701   0.504   0.399   0.293
66    H         0.248   0.262   0.260   0.627   0.644   0.652  -0.025  -0.015  -0.014
67    C        -0.269  -0.196  -0.321   0.082   0.196   0.015  -0.290  -0.191  -0.349
68    T         2.512   2.554   2.654   2.709   2.769   2.932   2.887   2.961   3.139
69    K         2.512   2.554   2.654   2.423   2.481   2.636   2.887   2.961   3.139
70    I         0.248   0.286   0.277  -0.096  -0.037  -0.063  -0.025   0.031   0.020
71    G         1.504   1.408   1.410   1.801   1.658   1.653   1.563   1.384   1.357
72    I         1.504   1.408   1.410   1.554   1.420   1.430   1.563   1.384   1.357
73    V         0.248   0.192   0.263   0.197   0.122   0.235  -0.025  -0.097  -0.007
74    C        -0.464  -0.494  -0.454  -0.118  -0.157  -0.098  -0.555  -0.583  -0.523
75    K         0.570   0.657   0.482   0.534   0.662   0.389   0.504   0.639   0.358
76    P         2.512   2.554   2.654   2.842   2.902   3.070   2.887   2.961   3.139
77    G        -1.498  -1.492  -1.450  -1.287  -1.242  -1.206  -1.085  -1.074  -1.010
78    T        -0.464  -0.497  -0.438  -0.541  -0.597  -0.498  -0.555  -0.586  -0.506
79    F        -0.269  -0.315  -0.343  -0.420  -0.467  -0.518  -0.290  -0.350  -0.377
80    D        -1.498  -1.492  -1.450  -1.115  -1.083  -1.027  -1.085  -1.074  -1.010
81    N         0.151   0.175   0.197  -0.015   0.017   0.070  -0.163  -0.132  -0.100
82    N         0.385   0.408   0.326   0.395   0.429   0.256   0.218   0.252   0.111
83    H        -1.090  -1.090  -1.032  -0.632  -0.629  -0.527  -0.926  -0.920  -0.844
84    K        -0.269  -0.201  -0.298  -0.166  -0.071  -0.203  -0.290  -0.197  -0.319
85    V         1.088   1.127   1.140   1.179   1.233   1.241   0.769   0.834   0.806
86    V        -0.269  -0.315  -0.343   0.003  -0.108  -0.132  -0.290  -0.350  -0.377
87    I        -0.981  -0.999  -0.961  -0.750  -0.813  -0.740  -0.820  -0.834  -0.776
88    T         0.248   0.193   0.256   0.249   0.155   0.245  -0.025  -0.094  -0.013
89    E        -0.464  -0.494  -0.454  -0.361  -0.384  -0.308  -0.555  -0.583  -0.523
90    I        -0.269  -0.315  -0.343  -0.357  -0.407  -0.439  -0.290  -0.350  -0.377
91    Q        -0.981  -0.987  -0.959  -0.780  -0.791  -0.759  -0.820  -0.823  -0.773
92    N        -0.464  -0.493  -0.443  -0.693  -0.751  -0.682  -0.555  -0.582  -0.511
93    F        -0.269  -0.299  -0.347  -0.215  -0.230  -0.266  -0.290  -0.330  -0.383
94    S         0.248   0.262   0.260   0.236   0.245   0.284  -0.025  -0.015  -0.014
95    R        -0.981  -0.990  -0.983  -0.889  -0.896  -0.862  -0.820  -0.825  -0.797
96    P        -0.464  -0.435  -0.427  -0.369  -0.317  -0.288  -0.555  -0.519  -0.494
97    L         0.570   0.505   0.441   0.366   0.269   0.165   0.504   0.399   0.293
98    F         0.248   0.193   0.256   0.426   0.353   0.449  -0.025  -0.094  -0.013
99    Y         0.248   0.193   0.256   0.302   0.244   0.320  -0.025  -0.094  -0.013
100   L         0.570   0.632   0.472   0.363   0.465   0.208   0.504   0.600   0.342
101   L         0.961   0.987   1.067   0.365   0.416   0.512   0.504   0.541   0.651
102   S         1.504   1.408   1.410   1.531   1.397   1.412   1.563   1.384   1.357
103   L         0.570   0.499   0.443   0.376   0.290   0.183   0.504   0.391   0.296
104   F        -0.269  -0.201  -0.298  -0.105   0.018  -0.174  -0.290  -0.197  -0.319
105   P        -0.269  -0.309  -0.345   0.125   0.067  -0.006  -0.290  -0.342  -0.380
106   L         0.248   0.193   0.256   0.029  -0.028   0.060  -0.025  -0.094  -0.013
107   F         1.088   1.134   1.169   0.979   1.071   1.076   0.769   0.849   0.869
108   Y        -1.498  -1.492  -1.450  -1.128  -1.120  -1.041  -1.085  -1.074  -1.010
109   N        -0.981  -0.983  -0.955  -0.750  -0.751  -0.704  -0.820  -0.819  -0.770
110   N        -0.269  -0.212  -0.298  -0.419  -0.334  -0.487  -0.290  -0.212  -0.320
111   K        -0.464  -0.428  -0.424  -0.367  -0.338  -0.302  -0.555  -0.511  -0.492
112   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   C        -0.464  -0.437  -0.437  -0.175  -0.125  -0.085  -0.555  -0.522  -0.504
130   P        -0.464  -0.499  -0.451  -0.315  -0.357  -0.257  -0.555  -0.589  -0.520
131   K        -0.464  -0.483  -0.432  -0.811  -0.862  -0.784  -0.555  -0.573  -0.500
132   Y         0.248   0.259   0.254   0.447   0.428   0.446  -0.025  -0.023  -0.023
133   F         0.570   0.525   0.443   0.789   0.717   0.541   0.504   0.429   0.296
134   T        -0.981  -0.990  -0.983  -0.543  -0.547  -0.551  -0.820  -0.825  -0.797
135   D        -0.464  -0.419  -0.425  -0.658  -0.580  -0.615  -0.555  -0.503  -0.493
136   Q        -0.981  -0.990  -0.983  -0.936  -0.923  -0.915  -0.820  -0.825  -0.797
137   L         0.248   0.313   0.286  -0.171  -0.073  -0.109  -0.025   0.066   0.033
138   D        -0.981  -0.986  -0.966  -1.158  -1.179  -1.158  -0.820  -0.822  -0.780
139   E        -0.981  -0.993  -0.964  -0.787  -0.782  -0.759  -0.820  -0.828  -0.779
140   S        -0.464  -0.494  -0.432  -0.365  -0.390  -0.306  -0.555  -0.583  -0.500
141   T        -0.464  -0.499  -0.436  -0.374  -0.419  -0.315  -0.555  -0.588  -0.504
142   L        -0.981  -0.996  -0.976  -1.146  -1.185  -1.120  -0.820  -0.832  -0.790
143   Q        -0.981  -0.990  -0.983  -0.928  -0.902  -0.879  -0.820  -0.825  -0.797
144   L         1.504   1.408   1.410   1.306   1.187   1.178   1.563   1.384   1.357
145   L        -0.269  -0.207  -0.308  -0.415  -0.314  -0.466  -0.290  -0.205  -0.333
146   D        -1.498  -1.492  -1.450  -1.345  -1.314  -1.266  -1.085  -1.074  -1.010
147   G         0.961   0.986   1.068   0.757   0.803   0.925   0.504   0.539   0.653
148   L        -0.269  -0.194  -0.301  -0.307  -0.188  -0.375  -0.290  -0.189  -0.323
149   R        -0.981  -0.940  -0.949  -0.872  -0.827  -0.809  -0.820  -0.771  -0.764
150   D        -1.498  -1.492  -1.450  -1.232  -1.220  -1.148  -1.085  -1.074  -1.010
151   F         1.088   1.131   1.144   0.725   0.798   0.802   0.769   0.842   0.817
152   I        -1.498  -1.492  -1.450  -1.362  -1.401  -1.283  -1.085  -1.074  -1.010
153   A        -0.269  -0.320  -0.335  -0.025  -0.089  -0.084  -0.290  -0.355  -0.368
154   E         1.504   1.408   1.410   1.409   1.252   1.253   1.563   1.384   1.357
155   L         0.570   0.525   0.443   0.366   0.317   0.167   0.504   0.429   0.296
156   Q        -1.498  -1.492  -1.450  -1.079  -1.101  -0.990  -1.085  -1.074  -1.010
157   E        -0.981  -0.986  -0.966  -0.992  -0.978  -0.959  -0.820  -0.822  -0.780
158   R        -0.981  -0.989  -0.963  -0.837  -0.871  -0.796  -0.820  -0.824  -0.778
159   L        -1.090  -1.090  -1.032  -1.443  -1.445  -1.367  -0.926  -0.920  -0.844
160   K         0.151   0.170   0.200  -0.228  -0.199  -0.183  -0.163  -0.138  -0.096
161   N        -0.470  -0.454  -0.435  -0.616  -0.592  -0.591  -0.544  -0.522  -0.493
162   D        -0.470  -0.450  -0.446  -0.568  -0.542  -0.541  -0.544  -0.516  -0.507
163   E        -0.591  -0.583  -0.521  -0.731  -0.722  -0.630  -0.687  -0.676  -0.595
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -0.591  -0.577  -0.521  -0.643  -0.605  -0.539  -0.687  -0.668  -0.595
171   -        -0.591  -0.577  -0.521  -0.859  -0.865  -0.763  -0.687  -0.668  -0.595
172   -         0.961   0.986   1.068   1.013   1.047   1.179   0.504   0.539   0.652
173   -         0.185   0.176   0.223  -0.028  -0.030   0.024  -0.092  -0.111  -0.050
174   -         0.185   0.176   0.223   0.110   0.065   0.164  -0.092  -0.111  -0.050
175   -         0.185   0.234   0.245  -0.164  -0.091  -0.093  -0.092  -0.019  -0.016
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   N        -0.591  -0.582  -0.521  -1.043  -1.028  -0.953  -0.687  -0.675  -0.595
178   A         0.053   0.071   0.139  -0.226  -0.213  -0.108  -0.290  -0.266  -0.179
179   S        -1.498  -1.492  -1.450  -1.269  -1.221  -1.187  -1.085  -1.074  -1.010
180   L        -0.981  -0.999  -0.961  -1.023  -1.065  -0.998  -0.820  -0.834  -0.776
181   D        -0.981  -0.983  -0.955  -1.093  -1.075  -1.067  -0.820  -0.819  -0.770
182   K        -0.269  -0.309  -0.345  -0.179  -0.225  -0.273  -0.290  -0.342  -0.380
183   E         0.248   0.310   0.268   0.192   0.298   0.201  -0.025   0.061   0.002
184   R         2.512   2.554   2.654   2.893   2.950   3.123   2.887   2.961   3.139
185   L         2.512   2.554   2.654   2.229   2.299   2.435   2.887   2.961   3.139
186   T         0.570   0.626   0.480   0.671   0.749   0.550   0.504   0.591   0.354
187   S         1.504   1.408   1.410   1.475   1.327   1.325   1.563   1.384   1.357
188   V         0.570   0.505   0.441   0.847   0.748   0.642   0.504   0.399   0.293
189   G         2.512   2.554   2.654   2.781   2.847   3.007   2.887   2.961   3.139
190   K         0.248   0.262   0.260   0.055   0.057   0.083  -0.025  -0.015  -0.014
191   I         1.088   1.069   1.121   0.695   0.634   0.668   0.769   0.715   0.766
192   F         1.504   1.547   1.429   1.996   2.060   1.914   1.563   1.636   1.396
193   N        -0.269  -0.299  -0.347  -0.270  -0.349  -0.398  -0.290  -0.330  -0.383
194   A        -0.464  -0.437  -0.437  -0.417  -0.394  -0.359  -0.555  -0.522  -0.504
195   C         2.512   2.554   2.654   2.942   3.004   3.173   2.887   2.961   3.139
196   D         1.088   1.069   1.121   0.775   0.711   0.768   0.769   0.715   0.766
197   S        -0.981  -0.983  -0.955  -0.928  -0.957  -0.882  -0.820  -0.819  -0.770
198   L         1.504   1.408   1.410   1.254   1.121   1.097   1.563   1.384   1.357
199   S        -0.464  -0.422  -0.427  -0.637  -0.603  -0.572  -0.555  -0.507  -0.495
200   N        -0.981  -0.929  -0.944  -1.100  -1.007  -1.051  -0.820  -0.759  -0.759
201   C         0.570   0.645   0.468   0.427   0.547   0.289   0.504   0.620   0.335
202   S        -0.464  -0.497  -0.438  -0.549  -0.578  -0.515  -0.555  -0.586  -0.506
203   K         0.248   0.193   0.260   0.012  -0.080   0.019  -0.025  -0.095  -0.011
204   A        -0.981  -0.924  -0.946  -0.847  -0.785  -0.779  -0.820  -0.754  -0.761
205   G         2.512   2.554   2.654   2.781   2.847   3.007   2.887   2.961   3.139
206   P        -0.981  -1.002  -0.971  -0.905  -0.955  -0.904  -0.820  -0.837  -0.786
207   Y         0.248   0.197   0.253   0.081   0.027   0.117  -0.025  -0.088  -0.018
208   G         2.512   2.554   2.654   2.781   2.847   3.007   2.887   2.961   3.139
209   I        -0.269  -0.314  -0.328  -0.375  -0.408  -0.443  -0.290  -0.348  -0.358
210   L         1.504   1.408   1.410   1.346   1.240   1.241   1.563   1.384   1.357
211   A        -0.464  -0.499  -0.436  -0.566  -0.646  -0.532  -0.555  -0.588  -0.504
212   N        -0.464  -0.438  -0.430  -0.688  -0.662  -0.630  -0.555  -0.522  -0.497
213   I        -0.981  -0.990  -0.983  -0.888  -0.939  -0.867  -0.820  -0.825  -0.797
214   L         0.248   0.191   0.255  -0.035  -0.086  -0.023  -0.025  -0.098  -0.018
215   K        -0.269  -0.290  -0.334  -0.324  -0.378  -0.440  -0.290  -0.319  -0.366
216   D        -0.981  -0.990  -0.983  -0.926  -0.927  -0.982  -0.820  -0.825  -0.797
217   N         0.570   0.494   0.436   0.638   0.531   0.450   0.504   0.382   0.285
218   V         0.248   0.313   0.286   0.316   0.411   0.405  -0.025   0.066   0.033
219   A        -0.981  -0.924  -0.946  -0.959  -0.879  -0.904  -0.820  -0.754  -0.761
220   I         0.570   0.494   0.436   0.417   0.335   0.229   0.504   0.382   0.285
221   M        -0.269  -0.194  -0.301  -0.370  -0.254  -0.401  -0.290  -0.189  -0.323
222   D         0.248   0.259   0.264   0.026   0.008   0.042  -0.025  -0.022  -0.008
223   D         2.512   2.554   2.654   2.484   2.541   2.700   2.887   2.961   3.139
224   T        -0.981  -0.990  -0.983  -0.623  -0.630  -0.625  -0.820  -0.825  -0.797
225   M        -0.981  -1.003  -0.964  -0.876  -0.861  -0.811  -0.820  -0.838  -0.778
226   N        -0.269  -0.314  -0.328  -0.398  -0.493  -0.514  -0.290  -0.348  -0.358
227   E         1.088   1.078   1.120   0.731   0.687   0.734   0.769   0.732   0.764
228   I         0.053   0.071   0.141  -0.317  -0.305  -0.217  -0.290  -0.267  -0.176
229   K        -0.269  -0.201  -0.298  -0.227  -0.143  -0.258  -0.290  -0.197  -0.319
230   E        -0.269  -0.295  -0.326  -0.264  -0.328  -0.343  -0.290  -0.324  -0.356
231   W         1.504   1.408   1.410   2.018   1.893   1.917   1.563   1.384   1.357
232   L         0.248   0.193   0.256  -0.088  -0.172  -0.088  -0.025  -0.094  -0.013
233   E         1.504   1.554   1.440   1.448   1.509   1.361   1.563   1.648   1.416
234   E        -0.464  -0.499  -0.451  -0.528  -0.563  -0.509  -0.555  -0.589  -0.520
235   P         1.504   1.408   1.410   1.868   1.721   1.724   1.563   1.384   1.357
236   D        -0.269  -0.191  -0.286  -0.193  -0.084  -0.217  -0.290  -0.185  -0.304
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   S        -0.591  -0.585  -0.521  -1.131  -1.123  -1.045  -0.687  -0.678  -0.595
240   A        -0.981  -0.989  -0.963  -0.907  -0.942  -0.873  -0.820  -0.824  -0.778
241   N        -0.269  -0.189  -0.300  -0.132  -0.005  -0.195  -0.290  -0.182  -0.322
242   S        -0.464  -0.484  -0.447  -0.482  -0.490  -0.421  -0.555  -0.573  -0.516
243   D         2.512   2.554   2.654   2.484   2.541   2.700   2.887   2.961   3.139
244   D         0.961   0.986   1.068   0.828   0.850   0.978   0.504   0.539   0.653
245   I         1.504   1.547   1.429   1.801   1.867   1.690   1.563   1.636   1.396
246   F         0.570   0.645   0.468   0.866   0.994   0.691   0.504   0.620   0.335
247   L        -0.981  -0.990  -0.983  -0.722  -0.755  -0.739  -0.820  -0.825  -0.797
248   D        -0.464  -0.494  -0.454  -0.720  -0.788  -0.713  -0.555  -0.583  -0.523
249   F         0.570   0.494   0.436   0.627   0.496   0.419   0.504   0.382   0.285
250   E        -0.464  -0.419  -0.434  -0.909  -0.838  -0.900  -0.555  -0.502  -0.501
251   D         0.248   0.295   0.280   0.018   0.085   0.080  -0.025   0.043   0.024
252   S         0.570   0.499   0.443   0.501   0.377   0.269   0.504   0.391   0.296
253   E        -0.269  -0.290  -0.334  -0.452  -0.511  -0.592  -0.290  -0.319  -0.366
254   S        -0.269  -0.299  -0.347  -0.471  -0.546  -0.640  -0.290  -0.330  -0.383
255   E         2.512   2.554   2.654   2.389   2.438   2.601   2.887   2.961   3.139
256   S        -1.498  -1.492  -1.450  -1.579  -1.527  -1.508  -1.085  -1.074  -1.010
257   D        -0.981  -0.999  -0.961  -0.822  -0.823  -0.767  -0.820  -0.834  -0.776
258   S        -0.464  -0.431  -0.429  -0.642  -0.604  -0.587  -0.555  -0.514  -0.496
259   Q        -0.981  -0.983  -0.955  -0.746  -0.776  -0.715  -0.820  -0.819  -0.770
260   K        -0.470  -0.455  -0.444  -0.528  -0.515  -0.492  -0.544  -0.523  -0.504
261   E        -0.470  -0.450  -0.446  -0.731  -0.705  -0.715  -0.544  -0.516  -0.507
262   E         0.385   0.415   0.345   0.165   0.204   0.060   0.218   0.264   0.141
263   F        -1.090  -1.090  -1.032  -0.917  -0.918  -0.823  -0.926  -0.920  -0.844
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   D         0.185   0.203   0.209   0.210   0.236   0.266  -0.092  -0.067  -0.073
270   Q        -0.981  -0.928  -0.952  -1.037  -0.964  -0.991  -0.820  -0.758  -0.766
271   E        -0.269  -0.309  -0.345  -0.380  -0.444  -0.519  -0.290  -0.342  -0.380
272   K        -0.269  -0.320  -0.335  -0.361  -0.435  -0.479  -0.290  -0.355  -0.368
273   V        -1.498  -1.492  -1.450  -0.890  -0.870  -0.795  -1.085  -1.074  -1.010
274   Y        -0.981  -0.928  -0.952  -0.933  -0.852  -0.883  -0.820  -0.758  -0.766
275   E         1.504   1.554   1.440   1.404   1.466   1.296   1.563   1.648   1.416
276   N        -0.464  -0.419  -0.424  -0.686  -0.635  -0.642  -0.555  -0.503  -0.492
277   I        -0.981  -0.990  -0.983  -0.937  -0.923  -0.889  -0.820  -0.825  -0.797
278   K         0.248   0.295   0.285  -0.067   0.010  -0.022  -0.025   0.045   0.030
279   L        -0.269  -0.299  -0.347  -0.432  -0.467  -0.589  -0.290  -0.330  -0.383
280   F         1.504   1.408   1.410   1.755   1.602   1.584   1.563   1.384   1.357
281   F        -0.981  -0.924  -0.946  -0.813  -0.698  -0.766  -0.820  -0.754  -0.761
282   D        -0.981  -0.924  -0.946  -0.920  -0.816  -0.874  -0.820  -0.754  -0.761
283   G        -0.981  -0.928  -0.952  -1.229  -1.121  -1.206  -0.820  -0.758  -0.766
284   F         0.248   0.249   0.255   0.305   0.269   0.280  -0.025  -0.034  -0.020
285   T        -0.981  -0.929  -0.944  -1.036  -0.967  -0.969  -0.820  -0.759  -0.759
286   R        -0.981  -0.928  -0.952  -0.663  -0.568  -0.616  -0.820  -0.758  -0.766
287   K         2.512   2.554   2.654   2.423   2.481   2.636   2.887   2.961   3.139
288   I         0.570   0.505   0.441   0.483   0.357   0.226   0.504   0.399   0.293
289   K        -0.269  -0.311  -0.334  -0.248  -0.318  -0.343  -0.290  -0.344  -0.366
290   L         0.570   0.525   0.443   0.490   0.436   0.342   0.504   0.429   0.296
291   I         0.570   0.505   0.441   0.612   0.535   0.408   0.504   0.399   0.293
292   K         2.512   2.554   2.654   2.423   2.481   2.636   2.887   2.961   3.139
293   L         1.504   1.408   1.410   1.254   1.121   1.097   1.563   1.384   1.357
294   L         2.512   2.554   2.654   2.229   2.299   2.435   2.887   2.961   3.139
295   V        -0.269  -0.320  -0.335  -0.415  -0.464  -0.503  -0.290  -0.355  -0.368
296   S         0.570   0.507   0.452   0.520   0.397   0.310   0.504   0.402   0.310
297   T         1.504   1.547   1.429   1.521   1.579   1.426   1.563   1.636   1.396
298   F        -0.269  -0.305  -0.326  -0.070  -0.138  -0.199  -0.290  -0.337  -0.356
299   R        -0.464  -0.434  -0.430  -0.551  -0.518  -0.478  -0.555  -0.518  -0.497
300   K         1.504   1.563   1.443   1.536   1.614   1.478   1.563   1.664   1.422
301   T         0.570   0.494   0.436   0.686   0.585   0.518   0.504   0.382   0.285
302   L        -0.464  -0.497  -0.438  -0.762  -0.770  -0.717  -0.555  -0.586  -0.506
303   V        -0.470  -0.502  -0.453  -0.507  -0.586  -0.515  -0.544  -0.582  -0.515
304   S        -1.090  -1.081  -1.032  -1.332  -1.298  -1.252  -0.926  -0.912  -0.844
305   K        -0.470  -0.483  -0.446  -0.428  -0.446  -0.377  -0.544  -0.560  -0.507
306   D        -1.090  -1.081  -1.032  -1.105  -1.109  -1.018  -0.926  -0.912  -0.844
307   F        -0.591  -0.578  -0.521  -0.523  -0.491  -0.415  -0.687  -0.670  -0.595
308   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   P         0.570   0.657   0.482   0.949   1.081   0.808   0.504   0.639   0.358
312   K        -0.981  -0.924  -0.946  -0.963  -0.855  -0.921  -0.820  -0.754  -0.761
313   R        -0.981  -0.993  -0.964  -0.572  -0.595  -0.529  -0.820  -0.828  -0.779
314   N        -0.464  -0.497  -0.443  -0.347  -0.380  -0.307  -0.555  -0.586  -0.512
315   Q        -0.464  -0.437  -0.437  -0.721  -0.691  -0.667  -0.555  -0.522  -0.504
316   A         1.088   1.130   1.145   1.217   1.285   1.293   0.769   0.840   0.819
317   E        -1.090  -1.090  -1.032  -1.146  -1.146  -1.060  -0.926  -0.920  -0.844
318   T        -0.470  -0.454  -0.435  -0.369  -0.340  -0.325  -0.544  -0.522  -0.493
319   L         1.006   1.032   1.099   0.397   0.435   0.515   0.599   0.636   0.720
320   D         0.385   0.401   0.345   0.298   0.315   0.210   0.218   0.242   0.141
321   S         0.570   0.626   0.480   0.497   0.569   0.346   0.504   0.591   0.354
322   I         0.961   0.986   1.067   0.365   0.398   0.502   0.504   0.538   0.651
323   H         0.570   0.494   0.436   0.894   0.790   0.733   0.504   0.382   0.285
324   T        -0.981  -0.924  -0.946  -0.815  -0.715  -0.760  -0.820  -0.754  -0.761
325   Y        -0.269  -0.314  -0.328  -0.282  -0.328  -0.329  -0.290  -0.348  -0.358
326   L        -0.464  -0.499  -0.451  -0.168  -0.215  -0.157  -0.555  -0.589  -0.520
327   K        -0.269  -0.207  -0.308  -0.229  -0.141  -0.283  -0.290  -0.205  -0.333
328   E        -0.981  -0.940  -0.949  -0.964  -0.869  -0.941  -0.820  -0.771  -0.764
329   I        -0.464  -0.484  -0.447  -0.731  -0.740  -0.678  -0.555  -0.573  -0.516
330   Q        -0.269  -0.299  -0.347  -0.032  -0.100  -0.175  -0.290  -0.330  -0.383
331   L        -0.981  -0.996  -0.976  -1.173  -1.192  -1.150  -0.820  -0.832  -0.790
332   L        -0.981  -0.983  -0.955  -1.137  -1.151  -1.090  -0.820  -0.819  -0.770
333   L         0.248   0.300   0.270  -0.181  -0.081  -0.173  -0.025   0.051   0.007
334   D         2.512   2.554   2.654   2.484   2.541   2.700   2.887   2.961   3.139
335   E        -0.464  -0.497  -0.443  -0.562  -0.625  -0.527  -0.555  -0.586  -0.512
336   V        -0.269  -0.320  -0.335  -0.415  -0.491  -0.503  -0.290  -0.355  -0.368
337   V         0.961   0.986   1.068   0.733   0.771   0.898   0.504   0.539   0.653
338   S        -0.269  -0.309  -0.345  -0.215  -0.275  -0.325  -0.290  -0.342  -0.380
339   T        -0.269  -0.315  -0.343  -0.179  -0.240  -0.287  -0.290  -0.350  -0.377
340   V        -0.464  -0.494  -0.454  -0.641  -0.689  -0.616  -0.555  -0.583  -0.523
341   Q        -0.464  -0.419  -0.434  -0.183  -0.110  -0.144  -0.555  -0.502  -0.501
342   F        -0.981  -1.003  -0.964  -0.627  -0.697  -0.610  -0.820  -0.838  -0.778
343   E        -0.464  -0.435  -0.427  -0.720  -0.680  -0.671  -0.555  -0.519  -0.494
344   P        -1.090  -1.090  -1.032  -0.652  -0.641  -0.549  -0.926  -0.920  -0.844
345   K        -0.470  -0.462  -0.445  -0.589  -0.587  -0.553  -0.544  -0.531  -0.505
346   N        -1.090  -1.090  -1.032  -0.762  -0.758  -0.663  -0.926  -0.920  -0.844
347   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   T        -0.591  -0.582  -0.521  -0.404  -0.371  -0.291  -0.687  -0.675  -0.595
349   N         0.570   0.645   0.468   0.577   0.688   0.402   0.504   0.620   0.335
350   E         0.248   0.302   0.289   0.010   0.081   0.081  -0.025   0.055   0.032
351   E         1.504   1.408   1.410   1.448   1.303   1.314   1.563   1.384   1.357
352   V        -0.981  -0.986  -0.966  -0.677  -0.679  -0.649  -0.820  -0.822  -0.780
353   K        -0.981  -0.928  -0.952  -1.024  -0.958  -0.977  -0.820  -0.758  -0.766
354   E        -1.498  -1.492  -1.450  -1.259  -1.247  -1.176  -1.085  -1.074  -1.010
355   E        -0.464  -0.431  -0.429  -0.601  -0.570  -0.533  -0.555  -0.514  -0.496
356   Q        -1.498  -1.492  -1.450  -1.418  -1.441  -1.342  -1.085  -1.074  -1.010
357   A        -0.981  -0.996  -0.976  -0.820  -0.861  -0.834  -0.820  -0.832  -0.790
358   A        -0.464  -0.497  -0.438  -0.321  -0.371  -0.260  -0.555  -0.586  -0.506
359   L         0.248   0.197   0.253  -0.079  -0.126  -0.075  -0.025  -0.088  -0.018
360   V        -0.981  -1.002  -0.971  -0.652  -0.655  -0.619  -0.820  -0.837  -0.786
361   A        -0.981  -0.989  -0.963  -0.759  -0.746  -0.727  -0.820  -0.824  -0.778
362   V        -1.498  -1.492  -1.450  -1.295  -1.307  -1.214  -1.085  -1.074  -1.010
363   T        -0.981  -0.924  -0.946  -0.647  -0.546  -0.587  -0.820  -0.754  -0.761
364   K        -0.981  -0.986  -0.966  -0.743  -0.735  -0.687  -0.820  -0.822  -0.780
365   K         1.504   1.408   1.410   1.482   1.345   1.348   1.563   1.384   1.357
366   V         0.248   0.310   0.268   0.034   0.115   0.093  -0.025   0.061   0.002
367   L        -0.981  -0.993  -0.964  -0.971  -0.951  -0.944  -0.820  -0.828  -0.779
368   I        -0.269  -0.201  -0.298  -0.284  -0.189  -0.332  -0.290  -0.197  -0.319
369   Q         0.570   0.618   0.476   0.575   0.649   0.417   0.504   0.579   0.349
370   M        -0.981  -1.002  -0.971  -0.588  -0.593  -0.528  -0.820  -0.837  -0.786
371   S        -0.981  -1.003  -0.964  -0.937  -0.984  -0.900  -0.820  -0.838  -0.778
372   K        -1.498  -1.492  -1.450  -1.620  -1.623  -1.551  -1.085  -1.074  -1.010
373   L        -0.464  -0.493  -0.436  -0.833  -0.880  -0.790  -0.555  -0.582  -0.504
374   Y        -0.464  -0.483  -0.432  -0.240  -0.259  -0.183  -0.555  -0.573  -0.500
375   E        -0.981  -1.003  -0.964  -0.907  -0.920  -0.867  -0.820  -0.838  -0.778
376   G        -0.981  -0.993  -0.964  -0.766  -0.814  -0.714  -0.820  -0.828  -0.779
377   D         0.570   0.632   0.472   0.681   0.767   0.549   0.504   0.600   0.342
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   P         0.248   0.296   0.276   0.244   0.327   0.268  -0.025   0.044   0.012
384   K        -0.269  -0.305  -0.326  -0.222  -0.255  -0.299  -0.290  -0.337  -0.356
385   R         0.570   0.494   0.436   0.679   0.574   0.518   0.504   0.382   0.285
386   K        -0.464  -0.436  -0.428  -0.966  -0.908  -0.926  -0.555  -0.521  -0.496
387   K         2.512   2.554   2.654   2.423   2.481   2.636   2.887   2.961   3.139
388   W         2.512   2.554   2.654   2.916   2.977   3.147   2.887   2.961   3.139
389   I        -0.269  -0.309  -0.345  -0.146  -0.241  -0.247  -0.290  -0.342  -0.380
390   D        -0.464  -0.428  -0.432  -0.577  -0.548  -0.513  -0.555  -0.512  -0.499
391   T        -0.464  -0.493  -0.436  -0.247  -0.293  -0.189  -0.555  -0.582  -0.504
392   W         1.504   1.554   1.440   1.996   2.069   1.931   1.563   1.648   1.416
393   E        -0.981  -0.921  -0.945  -1.184  -1.095  -1.140  -0.820  -0.751  -0.759
394   I         0.248   0.258   0.263   0.106   0.095   0.099  -0.025  -0.025  -0.010
395   K         1.504   1.408   1.410   1.499   1.366   1.375   1.563   1.384   1.357
396   F        -0.981  -0.987  -0.959  -0.587  -0.624  -0.543  -0.820  -0.823  -0.773
397   N        -0.981  -0.989  -0.963  -0.877  -0.872  -0.836  -0.820  -0.824  -0.778
398   E         0.385   0.347   0.338   0.128   0.038   0.003   0.218   0.154   0.129
399   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
400   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
401   F         0.185   0.172   0.200  -0.145  -0.164  -0.115  -0.092  -0.115  -0.086
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q05881
Output conservation file - output/Q05881
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
