1     M         2.036   2.057   2.113   2.367   2.405   2.497   2.267   2.298   2.387
2     T         0.684   0.599   0.600   0.773   0.640   0.629   0.597   0.450   0.439
3     V         0.370   0.385   0.428   0.140   0.156   0.228   0.041   0.066   0.129
4     S        -0.463  -0.489  -0.482  -0.426  -0.445  -0.446  -0.515  -0.547  -0.527
5     N        -1.296  -1.287  -1.261  -1.446  -1.422  -1.389  -1.072  -1.054  -1.008
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    I         0.506   0.531   0.505   0.441   0.486   0.421   0.288   0.330   0.270
11    G         0.506   0.518   0.502   0.522   0.543   0.493   0.288   0.307   0.264
12    G        -0.605  -0.600  -0.561  -0.514  -0.508  -0.439  -0.701  -0.690  -0.631
13    E         0.506   0.518   0.502   0.258   0.276   0.214   0.288   0.307   0.264
14    E         0.684   0.742   0.630   0.859   0.955   0.766   0.597   0.692   0.492
15    R        -1.296  -1.287  -1.261  -0.968  -0.958  -0.902  -1.072  -1.054  -1.008
16    L        -0.463  -0.501  -0.491  -0.579  -0.669  -0.619  -0.515  -0.563  -0.540
17    I        -0.463  -0.489  -0.482  -0.610  -0.650  -0.640  -0.515  -0.547  -0.527
18    I         0.506   0.546   0.524   0.368   0.432   0.394   0.288   0.357   0.305
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    L         2.036   2.057   2.113   1.922   1.953   2.044   2.267   2.298   2.387
21    P         2.036   2.057   2.113   2.194   2.239   2.321   2.267   2.298   2.387
22    D        -1.296  -1.287  -1.261  -1.496  -1.505  -1.440  -1.072  -1.054  -1.008
23    D        -0.463  -0.400  -0.461  -0.549  -0.444  -0.550  -0.515  -0.426  -0.500
24    Y        -1.296  -1.287  -1.261  -1.382  -1.400  -1.324  -1.072  -1.054  -1.008
25    E        -1.296  -1.287  -1.261  -1.336  -1.296  -1.277  -1.072  -1.054  -1.008
26    T        -0.463  -0.400  -0.461  -0.619  -0.518  -0.616  -0.515  -0.426  -0.500
27    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    T        -0.605  -0.600  -0.561  -0.642  -0.634  -0.570  -0.701  -0.690  -0.631
30    I        -1.296  -1.287  -1.261  -1.125  -1.101  -1.062  -1.072  -1.054  -1.008
31    N        -1.296  -1.287  -1.261  -1.297  -1.293  -1.237  -1.072  -1.054  -1.008
32    T        -0.463  -0.413  -0.463  -0.462  -0.385  -0.451  -0.515  -0.444  -0.502
33    F         0.684   0.599   0.600   0.814   0.669   0.662   0.597   0.450   0.439
34    T        -0.463  -0.489  -0.482  -0.603  -0.675  -0.649  -0.515  -0.547  -0.527
35    L         2.036   2.057   2.113   1.922   1.953   2.044   2.267   2.298   2.387
36    P         2.036   2.057   2.113   2.194   2.239   2.321   2.267   2.298   2.387
37    P        -1.296  -1.287  -1.261  -0.946  -0.939  -0.880  -1.072  -1.054  -1.008
38    P        -0.463  -0.501  -0.491  -0.385  -0.444  -0.444  -0.515  -0.563  -0.540
39    S         0.684   0.599   0.600   0.548   0.400   0.393   0.597   0.450   0.439
40    N         0.684   0.599   0.600   0.701   0.569   0.563   0.597   0.450   0.439
41    I        -0.463  -0.489  -0.482  -0.416  -0.437  -0.437  -0.515  -0.547  -0.527
42    T        -0.463  -0.489  -0.482  -0.603  -0.675  -0.649  -0.515  -0.547  -0.527
43    S         2.036   2.057   2.113   1.941   1.976   2.064   2.267   2.298   2.387
44    K        -0.463  -0.501  -0.491  -0.726  -0.770  -0.760  -0.515  -0.563  -0.540
45    P        -0.463  -0.413  -0.463  -0.728  -0.654  -0.723  -0.515  -0.444  -0.502
46    R        -0.605  -0.600  -0.561  -0.481  -0.473  -0.405  -0.701  -0.690  -0.631
47    I         0.506   0.504   0.496   0.357   0.352   0.332   0.288   0.281   0.254
48    E        -0.463  -0.489  -0.482  -0.809  -0.860  -0.842  -0.515  -0.547  -0.527
49    L         0.684   0.599   0.600   0.609   0.478   0.483   0.597   0.450   0.439
50    F         0.370   0.385   0.428   0.161   0.171   0.245   0.041   0.066   0.129
51    E        -1.296  -1.287  -1.261  -1.496  -1.494  -1.440  -1.072  -1.054  -1.008
52    N        -1.296  -1.287  -1.261  -0.927  -0.898  -0.860  -1.072  -1.054  -1.008
53    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    N        -0.463  -0.413  -0.463  -0.391  -0.306  -0.385  -0.515  -0.444  -0.502
55    G        -0.463  -0.413  -0.463  -0.354  -0.271  -0.344  -0.515  -0.444  -0.502
56    K        -0.463  -0.501  -0.491  -0.632  -0.666  -0.651  -0.515  -0.563  -0.540
57    L        -0.463  -0.414  -0.461  -0.610  -0.537  -0.607  -0.515  -0.445  -0.500
58    Y         0.684   0.599   0.600   0.854   0.726   0.727   0.597   0.450   0.439
59    E         0.370   0.383   0.427   0.322   0.333   0.409   0.041   0.062   0.126
60    I        -0.463  -0.413  -0.463  -0.610  -0.534  -0.609  -0.515  -0.444  -0.502
61    R        -0.605  -0.600  -0.561  -0.716  -0.712  -0.646  -0.701  -0.690  -0.631
62    S        -0.605  -0.600  -0.561  -0.825  -0.817  -0.756  -0.701  -0.690  -0.631
63    F        -0.605  -0.600  -0.561  -0.748  -0.742  -0.678  -0.701  -0.690  -0.631
64    Q        -0.605  -0.600  -0.561  -0.544  -0.534  -0.469  -0.701  -0.690  -0.631
65    F         2.036   2.057   2.113   2.200   2.238   2.327   2.267   2.298   2.387
66    G         0.506   0.518   0.502   0.513   0.535   0.483   0.288   0.307   0.264
67    K         2.036   2.057   2.113   1.758   1.790   1.876   2.267   2.298   2.387
68    G         2.036   2.057   2.113   2.218   2.257   2.346   2.267   2.298   2.387
69    P        -0.605  -0.600  -0.561  -0.323  -0.309  -0.244  -0.701  -0.690  -0.631
70    S        -0.605  -0.600  -0.561  -0.967  -0.966  -0.901  -0.701  -0.690  -0.631
71    Y         2.036   2.057   2.113   2.163   2.200   2.289   2.267   2.298   2.387
72    S        -0.605  -0.600  -0.561  -0.804  -0.794  -0.735  -0.701  -0.690  -0.631
73    H        -0.605  -0.600  -0.561  -0.529  -0.529  -0.454  -0.701  -0.690  -0.631
74    E        -0.605  -0.600  -0.561  -0.744  -0.734  -0.674  -0.701  -0.690  -0.631
75    E        -0.463  -0.413  -0.463  -0.412  -0.317  -0.430  -0.515  -0.444  -0.502
76    D         0.684   0.599   0.600   0.720   0.581   0.575   0.597   0.450   0.439
77    L        -0.463  -0.501  -0.491  -0.654  -0.729  -0.706  -0.515  -0.563  -0.540
78    A        -1.296  -1.287  -1.261  -1.345  -1.364  -1.286  -1.072  -1.054  -1.008
79    N         0.684   0.599   0.600   0.748   0.626   0.626   0.597   0.450   0.439
80    D         2.036   2.057   2.113   2.083   2.121   2.208   2.267   2.298   2.387
81    K        -0.463  -0.501  -0.491  -0.634  -0.693  -0.653  -0.515  -0.563  -0.540
82    Y         0.684   0.599   0.600   0.884   0.762   0.768   0.597   0.450   0.439
83    H         0.684   0.599   0.600   1.027   0.897   0.893   0.597   0.450   0.439
84    Y         0.684   0.599   0.600   0.767   0.618   0.609   0.597   0.450   0.439
85    T        -0.463  -0.501  -0.491  -0.455  -0.528  -0.514  -0.515  -0.563  -0.540
86    K        -1.296  -1.287  -1.261  -1.533  -1.502  -1.477  -1.072  -1.054  -1.008
87    E         0.370   0.383   0.427   0.151   0.174   0.243   0.041   0.062   0.126
88    N        -0.463  -0.414  -0.461  -0.468  -0.383  -0.463  -0.515  -0.445  -0.500
89    H        -0.463  -0.400  -0.461  -0.481  -0.404  -0.450  -0.515  -0.426  -0.500
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    P        -0.463  -0.490  -0.485  -0.381  -0.433  -0.427  -0.515  -0.548  -0.532
100   I        -1.296  -1.287  -1.261  -1.275  -1.255  -1.215  -1.072  -1.054  -1.008
101   K         0.684   0.721   0.620   0.502   0.554   0.423   0.597   0.657   0.476
102   S         2.036   2.057   2.113   1.941   1.976   2.064   2.267   2.298   2.387
103   T        -0.463  -0.501  -0.491  -0.285  -0.337  -0.317  -0.515  -0.563  -0.540
104   F         0.370   0.385   0.428   0.197   0.211   0.283   0.041   0.066   0.129
105   I        -1.296  -1.287  -1.261  -1.141  -1.110  -1.078  -1.072  -1.054  -1.008
106   V         0.506   0.518   0.502   0.441   0.461   0.415   0.288   0.307   0.264
107   N         2.036   2.057   2.113   2.037   2.075   2.161   2.267   2.298   2.387
108   T        -0.605  -0.600  -0.561  -0.764  -0.758  -0.694  -0.701  -0.690  -0.631
109   S         0.684   0.742   0.630   0.636   0.726   0.537   0.597   0.692   0.492
110   D        -0.463  -0.490  -0.485  -0.515  -0.570  -0.563  -0.515  -0.548  -0.532
111   P        -1.296  -1.287  -1.261  -1.234  -1.227  -1.173  -1.072  -1.054  -1.008
112   T        -0.463  -0.490  -0.485  -0.466  -0.490  -0.515  -0.515  -0.548  -0.532
113   D         0.370   0.385   0.428   0.165   0.191   0.257   0.041   0.066   0.129
114   G         0.684   0.721   0.620   0.902   0.965   0.805   0.597   0.657   0.476
115   Y        -1.296  -1.287  -1.261  -0.838  -0.801  -0.769  -1.072  -1.054  -1.008
116   V         0.684   0.740   0.630   0.740   0.830   0.643   0.597   0.689   0.492
117   F        -0.463  -0.489  -0.482  -0.508  -0.552  -0.524  -0.515  -0.547  -0.527
118   N        -1.296  -1.287  -1.261  -1.074  -1.031  -1.010  -1.072  -1.054  -1.008
119   S        -0.463  -0.414  -0.461  -0.577  -0.498  -0.573  -0.515  -0.445  -0.500
120   S        -1.296  -1.287  -1.261  -1.068  -1.037  -1.004  -1.072  -1.054  -1.008
121   K        -0.463  -0.400  -0.461  -0.672  -0.550  -0.688  -0.515  -0.426  -0.500
122   I         0.684   0.599   0.600   0.577   0.428   0.422   0.597   0.450   0.439
123   H        -1.296  -1.287  -1.261  -1.382  -1.376  -1.324  -1.072  -1.054  -1.008
124   F        -0.463  -0.489  -0.482  -0.301  -0.347  -0.326  -0.515  -0.547  -0.527
125   C        -1.296  -1.287  -1.261  -0.983  -0.992  -0.917  -1.072  -1.054  -1.008
126   S        -0.463  -0.490  -0.485  -0.564  -0.601  -0.595  -0.515  -0.548  -0.532
127   L         0.684   0.742   0.630   0.374   0.462   0.274   0.597   0.692   0.492
128   Y         0.684   0.599   0.600   0.854   0.726   0.727   0.597   0.450   0.439
129   D         0.684   0.599   0.600   0.726   0.590   0.584   0.597   0.450   0.439
130   I         0.684   0.742   0.630   0.544   0.631   0.449   0.597   0.692   0.492
131   A        -0.463  -0.489  -0.482  -0.317  -0.358  -0.339  -0.515  -0.547  -0.527
132   F         0.370   0.385   0.428   0.336   0.361   0.431   0.041   0.066   0.129
133   S        -0.463  -0.489  -0.482  -0.495  -0.528  -0.528  -0.515  -0.547  -0.527
134   L         0.684   0.740   0.630   0.544   0.629   0.449   0.597   0.689   0.492
135   I        -0.463  -0.490  -0.485  -0.279  -0.306  -0.275  -0.515  -0.548  -0.532
136   G         0.684   0.599   0.600   0.833   0.688   0.677   0.597   0.450   0.439
137   F        -0.463  -0.490  -0.485  -0.350  -0.410  -0.392  -0.515  -0.548  -0.532
138   Y        -0.463  -0.501  -0.491  -0.374  -0.416  -0.426  -0.515  -0.563  -0.540
139   Y         0.684   0.721   0.620   0.854   0.913   0.761   0.597   0.657   0.476
140   R        -0.463  -0.501  -0.491  -0.403  -0.478  -0.484  -0.515  -0.563  -0.540
141   N         0.684   0.721   0.620   0.701   0.762   0.598   0.597   0.657   0.476
142   S        -1.296  -1.287  -1.261  -1.141  -1.120  -1.078  -1.072  -1.054  -1.008
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   V         0.684   0.599   0.600   0.731   0.583   0.576   0.597   0.450   0.439
145   S        -0.463  -0.489  -0.482  -0.405  -0.435  -0.439  -0.515  -0.547  -0.527
146   A        -0.463  -0.414  -0.461  -0.311  -0.221  -0.310  -0.515  -0.445  -0.500
147   D        -0.463  -0.400  -0.461  -0.742  -0.648  -0.736  -0.515  -0.426  -0.500
148   E         0.506   0.518   0.502   0.401   0.420   0.383   0.288   0.307   0.264
149   Q        -0.605  -0.600  -0.561  -0.685  -0.682  -0.614  -0.701  -0.690  -0.631
150   D        -0.605  -0.600  -0.561  -0.619  -0.612  -0.547  -0.701  -0.690  -0.631
151   Y         0.506   0.518   0.502   0.570   0.591   0.560   0.288   0.307   0.264
152   S        -0.605  -0.600  -0.561  -0.740  -0.728  -0.670  -0.701  -0.690  -0.631
153   N        -0.605  -0.600  -0.561  -0.895  -0.893  -0.827  -0.701  -0.690  -0.631
154   S         0.506   0.531   0.505   0.456   0.502   0.433   0.288   0.330   0.270
155   S        -0.605  -0.600  -0.561  -0.559  -0.546  -0.485  -0.701  -0.690  -0.631
156   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   N        -0.605  -0.600  -0.561  -0.514  -0.499  -0.439  -0.701  -0.690  -0.631
161   Q        -0.605  -0.600  -0.561  -0.677  -0.679  -0.606  -0.701  -0.690  -0.631
162   K        -0.605  -0.600  -0.561  -0.853  -0.844  -0.785  -0.701  -0.690  -0.631
163   S        -0.605  -0.600  -0.561  -0.650  -0.638  -0.578  -0.701  -0.690  -0.631
164   N        -0.605  -0.600  -0.561  -0.776  -0.766  -0.706  -0.701  -0.690  -0.631
165   S        -0.605  -0.600  -0.561  -0.967  -0.966  -0.901  -0.701  -0.690  -0.631
166   K         0.506   0.518   0.502   0.288   0.306   0.302   0.288   0.307   0.264
167   T         0.506   0.531   0.505   0.439   0.481   0.428   0.288   0.330   0.270
168   N        -0.605  -0.600  -0.561  -0.701  -0.692  -0.629  -0.701  -0.690  -0.631
169   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   K        -0.463  -0.400  -0.461  -0.403  -0.279  -0.417  -0.515  -0.426  -0.500
171   F         0.684   0.721   0.620   0.875   0.935   0.779   0.597   0.657   0.476
172   L        -0.463  -0.490  -0.485  -0.590  -0.648  -0.622  -0.515  -0.548  -0.532
173   T         2.036   2.057   2.113   2.131   2.174   2.257   2.267   2.298   2.387
174   V        -1.296  -1.287  -1.261  -1.292  -1.260  -1.232  -1.072  -1.054  -1.008
175   R        -0.463  -0.490  -0.485  -0.340  -0.397  -0.396  -0.515  -0.548  -0.532
176   D         2.036   2.057   2.113   2.083   2.121   2.208   2.267   2.298   2.387
177   Y        -0.463  -0.501  -0.491  -0.202  -0.259  -0.227  -0.515  -0.563  -0.540
178   H        -0.463  -0.489  -0.482  -0.181  -0.244  -0.211  -0.515  -0.547  -0.527
179   D         0.684   0.740   0.630   0.720   0.810   0.628   0.597   0.689   0.492
180   F        -1.296  -1.287  -1.261  -1.130  -1.105  -1.067  -1.072  -1.054  -1.008
181   L         0.684   0.599   0.600   0.544   0.399   0.396   0.597   0.450   0.439
182   T        -0.463  -0.501  -0.491  -0.504  -0.578  -0.571  -0.515  -0.563  -0.540
183   D        -0.463  -0.490  -0.485  -0.515  -0.570  -0.563  -0.515  -0.548  -0.532
184   N         0.684   0.599   0.600   0.649   0.503   0.493   0.597   0.450   0.439
185   H        -0.463  -0.501  -0.491  -0.098  -0.158  -0.140  -0.515  -0.563  -0.540
186   D        -1.296  -1.287  -1.261  -1.165  -1.153  -1.102  -1.072  -1.054  -1.008
187   K        -1.296  -1.287  -1.261  -1.289  -1.254  -1.229  -1.072  -1.054  -1.008
188   N         2.036   2.057   2.113   2.045   2.083   2.169   2.267   2.298   2.387
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   W         2.036   2.057   2.113   2.440   2.482   2.572   2.267   2.298   2.387
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   E        -0.463  -0.501  -0.491  -0.485  -0.536  -0.529  -0.515  -0.563  -0.540
193   N        -1.296  -1.287  -1.261  -1.191  -1.151  -1.129  -1.072  -1.054  -1.008
194   I         0.684   0.599   0.600   0.642   0.509   0.511   0.597   0.450   0.439
195   S         0.684   0.742   0.630   0.800   0.904   0.701   0.597   0.692   0.492
196   L        -1.296  -1.287  -1.261  -1.154  -1.105  -1.091  -1.072  -1.054  -1.008
197   S        -1.296  -1.287  -1.261  -1.376  -1.333  -1.318  -1.072  -1.054  -1.008
198   R        -1.296  -1.287  -1.261  -1.000  -0.961  -0.935  -1.072  -1.054  -1.008
199   L        -0.463  -0.490  -0.485  -0.381  -0.425  -0.383  -0.515  -0.548  -0.532
200   K         0.370   0.383   0.427  -0.084  -0.077  -0.005   0.041   0.062   0.126
201   S         0.684   0.721   0.620   0.693   0.748   0.618   0.597   0.657   0.476
202   G        -0.463  -0.489  -0.482  -0.068  -0.106  -0.092  -0.515  -0.547  -0.527
203   L         2.036   2.057   2.113   1.922   1.953   2.044   2.267   2.298   2.387
204   A        -0.463  -0.400  -0.461  -0.432  -0.342  -0.414  -0.515  -0.426  -0.500
205   K        -0.463  -0.501  -0.491  -0.760  -0.821  -0.800  -0.515  -0.563  -0.540
206   V         0.684   0.742   0.630   0.642   0.728   0.560   0.597   0.692   0.492
207   S         0.684   0.599   0.600   0.701   0.589   0.599   0.597   0.450   0.439
208   E        -0.463  -0.414  -0.461  -0.366  -0.296  -0.350  -0.515  -0.445  -0.500
209   T         0.684   0.721   0.620   0.860   0.923   0.778   0.597   0.657   0.476
210   I         0.684   0.740   0.630   0.642   0.726   0.560   0.597   0.689   0.492
211   E         2.036   2.057   2.113   2.025   2.058   2.149   2.267   2.298   2.387
212   E         2.036   2.057   2.113   2.025   2.058   2.149   2.267   2.298   2.387
213   A         0.684   0.599   0.600   0.865   0.727   0.720   0.597   0.450   0.439
214   G         0.684   0.599   0.600   0.877   0.743   0.736   0.597   0.450   0.439
215   D         0.684   0.599   0.600   0.720   0.581   0.575   0.597   0.450   0.439
216   V        -0.463  -0.489  -0.482  -0.749  -0.799  -0.773  -0.515  -0.547  -0.527
217   Y         0.684   0.599   0.600   0.854   0.726   0.727   0.597   0.450   0.439
218   Y         2.036   2.057   2.113   2.165   2.203   2.292   2.267   2.298   2.387
219   K         0.684   0.740   0.630   0.502   0.580   0.436   0.597   0.689   0.492
220   I         0.684   0.599   0.600   0.657   0.527   0.530   0.597   0.450   0.439
221   T        -0.463  -0.490  -0.485  -0.481  -0.536  -0.532  -0.515  -0.548  -0.532
222   S        -1.296  -1.287  -1.261  -1.339  -1.319  -1.280  -1.072  -1.054  -1.008
223   A        -0.463  -0.414  -0.461  -0.216  -0.134  -0.205  -0.515  -0.445  -0.500
224   M         0.370   0.385   0.428   0.179   0.176   0.252   0.041   0.066   0.129
225   I         0.684   0.599   0.600   0.642   0.509   0.511   0.597   0.450   0.439
226   T        -1.296  -1.287  -1.261  -1.314  -1.309  -1.254  -1.072  -1.054  -1.008
227   Q        -0.463  -0.413  -0.463  -0.401  -0.328  -0.390  -0.515  -0.444  -0.502
228   F        -0.463  -0.400  -0.461  -0.167  -0.073  -0.145  -0.515  -0.426  -0.500
229   L         2.036   2.057   2.113   1.922   1.953   2.044   2.267   2.298   2.387
230   L        -0.463  -0.501  -0.491  -0.590  -0.625  -0.632  -0.515  -0.563  -0.540
231   G        -1.296  -1.287  -1.261  -1.272  -1.229  -1.212  -1.072  -1.054  -1.008
232   K         2.036   2.057   2.113   1.766   1.799   1.884   2.267   2.298   2.387
233   V         0.684   0.721   0.620   0.740   0.799   0.626   0.597   0.657   0.476
234   S        -0.463  -0.414  -0.461  -0.592  -0.515  -0.590  -0.515  -0.445  -0.500
235   K        -0.463  -0.501  -0.491  -0.623  -0.655  -0.641  -0.515  -0.563  -0.540
236   I         0.684   0.599   0.600   0.577   0.428   0.422   0.597   0.450   0.439
237   V        -0.463  -0.490  -0.485  -0.489  -0.551  -0.540  -0.515  -0.548  -0.532
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   E        -0.463  -0.490  -0.485  -0.566  -0.625  -0.612  -0.515  -0.548  -0.532
245   N         0.684   0.599   0.600   0.701   0.569   0.563   0.597   0.450   0.439
246   F         0.684   0.599   0.600   0.799   0.650   0.641   0.597   0.450   0.439
247   P         0.684   0.599   0.600   0.800   0.661   0.645   0.597   0.450   0.439
248   P        -1.296  -1.287  -1.261  -1.204  -1.196  -1.143  -1.072  -1.054  -1.008
249   S         0.684   0.599   0.600   0.564   0.421   0.415   0.597   0.450   0.439
250   I         0.370   0.383   0.427  -0.009   0.005   0.077   0.041   0.062   0.126
251   P        -0.463  -0.413  -0.463  -0.728  -0.654  -0.723  -0.515  -0.444  -0.502
252   T        -0.463  -0.413  -0.463  -0.495  -0.418  -0.488  -0.515  -0.444  -0.502
253   L        -0.463  -0.489  -0.482  -0.545  -0.610  -0.609  -0.515  -0.547  -0.527
254   K        -0.463  -0.501  -0.491  -0.555  -0.586  -0.563  -0.515  -0.563  -0.540
255   N        -0.463  -0.489  -0.482  -0.603  -0.651  -0.635  -0.515  -0.547  -0.527
256   A         0.684   0.742   0.630   0.630   0.712   0.557   0.597   0.692   0.492
257   P        -0.463  -0.501  -0.491  -0.307  -0.361  -0.354  -0.515  -0.563  -0.540
258   T        -1.296  -1.287  -1.261  -1.270  -1.227  -1.209  -1.072  -1.054  -1.008
259   E        -1.296  -1.287  -1.261  -1.202  -1.167  -1.140  -1.072  -1.054  -1.008
260   I         0.684   0.721   0.620   0.630   0.686   0.528   0.597   0.657   0.476
261   K        -1.296  -1.287  -1.261  -1.481  -1.470  -1.425  -1.072  -1.054  -1.008
262   Q        -1.296  -1.287  -1.261  -1.210  -1.202  -1.148  -1.072  -1.054  -1.008
263   C        -1.296  -1.287  -1.261  -0.968  -0.943  -0.902  -1.072  -1.054  -1.008
264   Y        -1.296  -1.287  -1.261  -1.267  -1.265  -1.206  -1.072  -1.054  -1.008
265   K         0.684   0.599   0.600   0.416   0.282   0.278   0.597   0.450   0.439
266   V        -1.296  -1.287  -1.261  -1.084  -1.075  -1.020  -1.072  -1.054  -1.008
267   V        -0.463  -0.413  -0.463  -0.466  -0.392  -0.456  -0.515  -0.444  -0.502
268   M        -0.463  -0.501  -0.491  -0.195  -0.256  -0.254  -0.515  -0.563  -0.540
269   A         0.370   0.383   0.427   0.197   0.209   0.281   0.041   0.062   0.126
270   T        -1.296  -1.287  -1.261  -1.094  -1.081  -1.030  -1.072  -1.054  -1.008
271   N         0.684   0.599   0.600   0.665   0.523   0.515   0.597   0.450   0.439
272   L         0.684   0.721   0.620   0.544   0.598   0.432   0.597   0.657   0.476
273   L         0.684   0.599   0.600   0.660   0.540   0.551   0.597   0.450   0.439
274   V         0.684   0.599   0.600   0.725   0.575   0.568   0.597   0.450   0.439
275   S         2.036   2.057   2.113   1.941   1.976   2.064   2.267   2.298   2.387
276   L         0.684   0.599   0.600   0.544   0.399   0.396   0.597   0.450   0.439
277   I         0.684   0.721   0.620   0.642   0.697   0.544   0.597   0.657   0.476
278   P         2.036   2.057   2.113   2.156   2.194   2.283   2.267   2.298   2.387
279   R        -0.463  -0.414  -0.461  -0.287  -0.202  -0.290  -0.515  -0.445  -0.500
280   A        -1.296  -1.287  -1.261  -1.125  -1.080  -1.062  -1.072  -1.054  -1.008
281   A        -0.463  -0.501  -0.491  -0.420  -0.500  -0.491  -0.515  -0.563  -0.540
282   Y        -0.463  -0.501  -0.491  -0.364  -0.441  -0.414  -0.515  -0.563  -0.540
283   H        -1.296  -1.287  -1.261  -0.917  -0.914  -0.850  -1.072  -1.054  -1.008
284   N        -1.296  -1.287  -1.261  -1.405  -1.400  -1.347  -1.072  -1.054  -1.008
285   L         0.684   0.599   0.600   0.544   0.399   0.396   0.597   0.450   0.439
286   L        -1.296  -1.287  -1.261  -1.063  -1.016  -0.999  -1.072  -1.054  -1.008
287   T        -1.296  -1.287  -1.261  -0.993  -0.967  -0.927  -1.072  -1.054  -1.008
288   F        -1.296  -1.287  -1.261  -1.071  -1.077  -1.007  -1.072  -1.054  -1.008
289   S        -1.296  -1.287  -1.261  -1.275  -1.244  -1.215  -1.072  -1.054  -1.008
290   P        -0.605  -0.597  -0.561  -0.638  -0.617  -0.565  -0.701  -0.685  -0.631
291   T         0.506   0.543   0.525   0.585   0.657   0.610   0.288   0.351   0.305
292   M         0.506   0.543   0.525   0.465   0.519   0.504   0.288   0.351   0.305
293   D         0.506   0.543   0.525   0.384   0.446   0.407   0.288   0.351   0.305
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   C        -1.296  -1.287  -1.261  -1.159  -1.120  -1.097  -1.072  -1.054  -1.008
298   L        -1.296  -1.287  -1.261  -1.311  -1.284  -1.252  -1.072  -1.054  -1.008
299   N        -0.463  -0.501  -0.491  -0.346  -0.383  -0.371  -0.515  -0.563  -0.540
300   P        -1.296  -1.287  -1.261  -1.322  -1.303  -1.263  -1.072  -1.054  -1.008
301   D        -0.463  -0.413  -0.463  -0.532  -0.445  -0.536  -0.515  -0.444  -0.502
302   I        -0.463  -0.501  -0.491  -0.542  -0.613  -0.586  -0.515  -0.563  -0.540
303   K         0.684   0.599   0.600   0.502   0.385   0.394   0.597   0.450   0.439
304   A        -0.463  -0.489  -0.482  -0.146  -0.190  -0.172  -0.515  -0.547  -0.527
305   S        -1.296  -1.287  -1.261  -1.074  -1.069  -1.010  -1.072  -1.054  -1.008
306   F         2.036   2.057   2.113   2.198   2.236   2.326   2.267   2.298   2.387
307   I        -0.463  -0.413  -0.463  -0.364  -0.281  -0.356  -0.515  -0.444  -0.502
308   E        -1.296  -1.287  -1.261  -1.508  -1.517  -1.453  -1.072  -1.054  -1.008
309   L        -0.463  -0.414  -0.461  -0.590  -0.518  -0.585  -0.515  -0.445  -0.500
310   E        -0.463  -0.490  -0.485  -0.504  -0.553  -0.540  -0.515  -0.548  -0.532
311   N        -1.296  -1.287  -1.261  -1.303  -1.259  -1.243  -1.072  -1.054  -1.008
312   Y         0.684   0.721   0.620   0.854   0.913   0.761   0.597   0.657   0.476
313   E        -1.296  -1.287  -1.261  -1.469  -1.461  -1.413  -1.072  -1.054  -1.008
314   T        -0.463  -0.400  -0.461  -0.710  -0.615  -0.701  -0.515  -0.426  -0.500
315   T        -0.463  -0.490  -0.485  -0.420  -0.462  -0.462  -0.515  -0.548  -0.532
316   N        -1.296  -1.287  -1.261  -1.348  -1.337  -1.289  -1.072  -1.054  -1.008
317   E        -0.463  -0.413  -0.463  -0.581  -0.504  -0.578  -0.515  -0.444  -0.502
318   L        -1.296  -1.287  -1.261  -1.089  -1.061  -1.025  -1.072  -1.054  -1.008
319   Q        -0.463  -0.414  -0.461  -0.346  -0.250  -0.357  -0.515  -0.445  -0.500
320   N        -1.296  -1.287  -1.261  -1.146  -1.108  -1.083  -1.072  -1.054  -1.008
321   A        -0.463  -0.490  -0.485  -0.354  -0.432  -0.402  -0.515  -0.548  -0.532
322   E         2.036   2.057   2.113   2.025   2.058   2.149   2.267   2.298   2.387
323   R        -0.463  -0.501  -0.491  -0.226  -0.313  -0.277  -0.515  -0.563  -0.540
324   E         0.684   0.721   0.620   0.580   0.639   0.447   0.597   0.657   0.476
325   L         0.506   0.504   0.496   0.270   0.263   0.235   0.288   0.281   0.254
326   L         2.036   2.057   2.113   1.922   1.953   2.044   2.267   2.298   2.387
327   M        -1.296  -1.287  -1.261  -1.178  -1.165  -1.116  -1.072  -1.054  -1.008
328   K         0.370   0.385   0.428  -0.084  -0.051   0.014   0.041   0.066   0.129
329   S         0.370   0.383   0.427   0.197   0.209   0.281   0.041   0.062   0.126
330   A         0.684   0.599   0.600   0.865   0.727   0.720   0.597   0.450   0.439
331   M         0.684   0.721   0.620   1.026   1.089   0.924   0.597   0.657   0.476
332   N         0.684   0.740   0.630   0.655   0.748   0.556   0.597   0.689   0.492
333   V        -0.463  -0.490  -0.485  -0.322  -0.356  -0.347  -0.515  -0.548  -0.532
334   G        -0.463  -0.490  -0.485  -0.238  -0.284  -0.268  -0.515  -0.548  -0.532
335   L        -1.296  -1.287  -1.261  -1.178  -1.157  -1.116  -1.072  -1.054  -1.008
336   N        -0.463  -0.489  -0.482  -0.383  -0.428  -0.423  -0.515  -0.547  -0.527
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   S        -0.463  -0.490  -0.485  -0.555  -0.590  -0.586  -0.515  -0.548  -0.532
340   N        -0.463  -0.489  -0.482  -0.309  -0.347  -0.344  -0.515  -0.547  -0.527
341   G        -0.463  -0.413  -0.463  -0.287  -0.200  -0.276  -0.515  -0.444  -0.502
342   R         0.370   0.383   0.427   0.122   0.123   0.199   0.041   0.062   0.126
343   V        -0.463  -0.414  -0.461  -0.283  -0.205  -0.269  -0.515  -0.445  -0.500
344   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   V        -0.463  -0.501  -0.491  -0.412  -0.506  -0.462  -0.515  -0.563  -0.540
348   K         0.684   0.721   0.620   0.429   0.484   0.329   0.597   0.657   0.476
349   K         0.684   0.599   0.600   0.429   0.298   0.296   0.597   0.450   0.439
350   V        -1.296  -1.287  -1.261  -1.202  -1.181  -1.140  -1.072  -1.054  -1.008
351   T        -0.463  -0.489  -0.482  -0.453  -0.518  -0.504  -0.515  -0.547  -0.527
352   K         0.684   0.740   0.630   0.390   0.476   0.295   0.597   0.689   0.492
353   K         0.684   0.740   0.630   0.510   0.589   0.447   0.597   0.689   0.492
354   I        -0.463  -0.400  -0.461  -0.588  -0.468  -0.603  -0.515  -0.426  -0.500
355   V         0.684   0.740   0.630   0.822   0.907   0.747   0.597   0.689   0.492
356   Q        -1.296  -1.287  -1.261  -1.074  -1.035  -1.010  -1.072  -1.054  -1.008
357   N        -0.605  -0.595  -0.561  -0.874  -0.876  -0.806  -0.701  -0.683  -0.631
358   K         0.684   0.740   0.630   0.442   0.525   0.361   0.597   0.689   0.492
359   K         0.684   0.599   0.600   0.409   0.272   0.269   0.597   0.450   0.439
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   P         0.684   0.599   0.600   0.911   0.795   0.794   0.597   0.450   0.439
362   K         2.036   2.057   2.113   1.766   1.799   1.884   2.267   2.298   2.387
363   V         2.036   2.057   2.113   2.122   2.157   2.248   2.267   2.298   2.387
364   A         2.036   2.057   2.113   2.227   2.266   2.354   2.267   2.298   2.387
365   I        -0.463  -0.400  -0.461  -0.588  -0.468  -0.603  -0.515  -0.426  -0.500
366   G         2.036   2.057   2.113   2.227   2.267   2.354   2.267   2.298   2.387
367   K         0.684   0.721   0.620   0.502   0.554   0.423   0.597   0.657   0.476
368   G         2.036   2.057   2.113   2.227   2.267   2.354   2.267   2.298   2.387
369   A         0.684   0.740   0.630   0.943   1.030   0.872   0.597   0.689   0.492
370   I         0.684   0.599   0.600   0.577   0.428   0.422   0.597   0.450   0.439
371   D         2.036   2.057   2.113   2.083   2.121   2.208   2.267   2.298   2.387
372   G         2.036   2.057   2.113   2.227   2.267   2.354   2.267   2.298   2.387
373   F         2.036   2.057   2.113   2.198   2.236   2.326   2.267   2.298   2.387
374   F         2.036   2.057   2.113   2.198   2.236   2.326   2.267   2.298   2.387
375   K         2.036   2.057   2.113   1.766   1.799   1.884   2.267   2.298   2.387
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   R         0.684   0.742   0.630   0.502   0.582   0.436   0.597   0.692   0.492
379   K        -0.463  -0.490  -0.485  -0.625  -0.649  -0.636  -0.515  -0.548  -0.532
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q05635
Output conservation file - output/Q05635
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
