1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    M         0.344   0.302   0.311   0.432   0.367   0.336   0.134   0.052   0.020
20    Q        -0.216  -0.235  -0.299  -0.149  -0.186  -0.293  -0.389  -0.422  -0.503
21    V         0.127   0.139   0.252  -0.129  -0.113   0.070  -0.284  -0.266  -0.097
22    K        -1.201  -1.207  -1.161  -1.292  -1.289  -1.214  -1.121  -1.112  -1.017
23    S         0.180   0.163   0.258   0.031   0.000   0.136  -0.180  -0.218  -0.085
24    I         0.652   0.660   0.445   0.729   0.740   0.421   0.658   0.669   0.275
25    K        -0.735  -0.745  -0.773  -0.685  -0.696  -0.733  -0.807  -0.816  -0.812
26    M         1.277   1.285   1.356   1.412   1.434   1.528   1.390   1.402   1.502
27    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    W        -0.216  -0.132  -0.273   0.063   0.194  -0.025  -0.389  -0.254  -0.461
29    E        -1.884  -1.911  -1.738  -1.623  -1.702  -1.481  -1.435  -1.446  -1.236
30    S        -0.504  -0.501  -0.718  -0.399  -0.399  -0.750  -0.494  -0.488  -0.744
31    G        -1.201  -1.178  -1.156  -1.249  -1.222  -1.166  -1.121  -1.096  -1.012
32    G        -0.504  -0.576  -0.727  -0.360  -0.460  -0.693  -0.494  -0.584  -0.755
33    V        -0.735  -0.745  -0.773  -0.731  -0.747  -0.762  -0.807  -0.816  -0.812
34    N         1.277   1.285   1.356   1.292   1.304   1.414   1.390   1.402   1.502
35    Y         1.277   1.285   1.356   1.396   1.412   1.513   1.390   1.402   1.502
36    C        -0.447  -0.407  -0.368  -0.496  -0.437  -0.382  -0.703  -0.644  -0.593
37    Y         1.277   1.285   1.356   1.396   1.412   1.513   1.390   1.402   1.502
38    L         0.652   0.660   0.445   0.645   0.653   0.354   0.658   0.669   0.275
39    L         0.180   0.190   0.264  -0.096  -0.087   0.028  -0.180  -0.164  -0.072
40    S        -1.309  -1.285  -1.184  -1.404  -1.382  -1.217  -1.226  -1.202  -1.038
41    D        -0.216  -0.264  -0.302  -0.207  -0.277  -0.320  -0.389  -0.464  -0.506
42    S        -1.201  -1.197  -1.150  -1.215  -1.187  -1.116  -1.121  -1.103  -1.007
43    K        -1.201  -1.204  -1.147  -1.256  -1.256  -1.174  -1.121  -1.110  -1.004
44    N        -0.735  -0.741  -0.780  -0.755  -0.764  -0.788  -0.807  -0.814  -0.821
45    K         0.057  -0.016  -0.213   0.073  -0.013  -0.302   0.030  -0.074  -0.370
46    K        -1.597  -1.575  -1.468  -1.529  -1.501  -1.353  -1.331  -1.308  -1.142
47    S        -0.339  -0.347  -0.327  -0.461  -0.473  -0.436  -0.598  -0.604  -0.546
48    W        -0.216  -0.273  -0.307  -0.021  -0.125  -0.210  -0.389  -0.474  -0.512
49    L        -0.339  -0.343  -0.332  -0.520  -0.532  -0.483  -0.598  -0.607  -0.554
50    I         0.344   0.302   0.311   0.287   0.209   0.193   0.134   0.052   0.020
51    D         1.277   1.285   1.356   1.225   1.241   1.351   1.390   1.402   1.502
52    P         0.652   0.716   0.456   0.777   0.859   0.502   0.658   0.755   0.295
53    A         1.277   1.285   1.356   1.280   1.288   1.403   1.390   1.402   1.502
54    E        -0.504  -0.474  -0.706  -0.344  -0.311  -0.617  -0.494  -0.456  -0.730
55    P         0.057   0.052  -0.204   0.230   0.219  -0.162   0.030   0.019  -0.356
56    P        -1.488  -1.489  -1.445  -1.387  -1.391  -1.347  -1.226  -1.223  -1.123
57    E        -1.022  -1.012  -1.115  -0.858  -0.849  -0.994  -0.912  -0.902  -0.971
58    V         1.277   1.285   1.356   1.248   1.257   1.373   1.390   1.402   1.502
59    L        -1.201  -1.242  -1.151  -1.104  -1.147  -0.991  -1.121  -1.149  -1.009
60    P        -0.216  -0.115  -0.279  -0.191  -0.040  -0.306  -0.389  -0.243  -0.471
61    E        -1.309  -1.315  -1.187  -1.305  -1.324  -1.129  -1.226  -1.220  -1.041
62    L        -0.735  -0.684  -0.758  -0.761  -0.679  -0.786  -0.807  -0.729  -0.794
63    T        -1.022  -0.950  -1.108  -0.999  -0.891  -1.148  -0.912  -0.832  -0.964
64    E         0.180   0.181   0.265  -0.154  -0.150  -0.025  -0.180  -0.181  -0.070
65    D        -1.597  -1.590  -1.479  -1.591  -1.591  -1.427  -1.331  -1.315  -1.150
66    E        -1.597  -1.605  -1.482  -1.632  -1.651  -1.485  -1.331  -1.329  -1.152
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -0.928  -0.856  -0.824  -1.153  -1.055  -0.988  -1.028  -0.953  -0.869
70    K        -1.309  -1.296  -1.184  -1.358  -1.332  -1.161  -1.226  -1.207  -1.039
71    I        -0.216  -0.148  -0.267  -0.205  -0.093  -0.292  -0.389  -0.275  -0.452
72    S        -1.201  -1.121  -1.152  -1.225  -1.110  -1.163  -1.121  -1.044  -1.008
73    V         0.344   0.349   0.332   0.199   0.200   0.156   0.134   0.140   0.061
74    E        -1.597  -1.590  -1.479  -1.548  -1.514  -1.387  -1.331  -1.315  -1.150
75    A         0.652   0.637   0.448   0.750   0.730   0.483   0.658   0.633   0.281
76    I         0.652   0.641   0.445   0.729   0.716   0.422   0.658   0.640   0.276
77    V         0.344   0.302   0.311   0.232   0.149   0.135   0.134   0.052   0.020
78    N         0.344   0.302   0.311   0.267   0.187   0.161   0.134   0.052   0.020
79    T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
80    H         1.277   1.285   1.356   1.324   1.334   1.445   1.390   1.402   1.502
81    H         1.277   1.285   1.356   1.324   1.334   1.445   1.390   1.402   1.502
82    H         1.277   1.285   1.356   1.324   1.334   1.445   1.390   1.402   1.502
83    Y        -0.216  -0.278  -0.306  -0.030  -0.115  -0.171  -0.389  -0.471  -0.512
84    D         1.277   1.285   1.356   1.225   1.241   1.351   1.390   1.402   1.502
85    H         1.277   1.285   1.356   1.324   1.334   1.445   1.390   1.402   1.502
86    A         0.127   0.138   0.252  -0.098  -0.082   0.097  -0.284  -0.267  -0.097
87    D         0.344   0.392   0.325   0.235   0.310   0.170   0.134   0.218   0.048
88    G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
89    N         1.277   1.285   1.356   1.292   1.304   1.414   1.390   1.402   1.502
90    A        -1.597  -1.547  -1.465  -1.614  -1.564  -1.413  -1.331  -1.288  -1.141
91    D        -1.022  -1.056  -1.111  -0.904  -0.957  -1.060  -0.912  -0.948  -0.967
92    I        -0.518  -0.503  -0.385  -0.722  -0.710  -0.524  -0.807  -0.784  -0.617
93    L        -0.914  -0.898  -0.818  -1.051  -1.033  -0.885  -1.017  -0.992  -0.863
94    K        -1.022  -0.984  -1.107  -0.972  -0.913  -1.104  -0.912  -0.870  -0.963
95    Y        -1.597  -1.620  -1.475  -1.465  -1.478  -1.274  -1.331  -1.339  -1.147
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    L        -0.447  -0.385  -0.349  -0.516  -0.424  -0.392  -0.703  -0.614  -0.568
99    K        -0.216  -0.211  -0.292  -0.225  -0.216  -0.361  -0.389  -0.382  -0.488
100   E        -1.597  -1.621  -1.485  -1.589  -1.612  -1.419  -1.331  -1.340  -1.155
101   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   V         0.344   0.320   0.303   0.199   0.151   0.102   0.134   0.086   0.005
108   E        -1.201  -1.253  -1.167  -1.162  -1.250  -1.134  -1.121  -1.163  -1.024
109   V         0.180   0.181   0.265  -0.016  -0.022   0.100  -0.180  -0.181  -0.070
110   I         0.344   0.302   0.311   0.335   0.267   0.265   0.134   0.052   0.020
111   G         0.180   0.232   0.285  -0.040   0.049   0.121  -0.180  -0.081  -0.030
112   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
113   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   K         0.057  -0.016  -0.213   0.057  -0.031  -0.333   0.030  -0.074  -0.370
115   D         0.057   0.027  -0.207   0.131   0.095  -0.258   0.030  -0.013  -0.360
116   C        -0.805  -0.842  -0.797  -0.680  -0.711  -0.640  -0.912  -0.939  -0.841
117   P        -1.022  -1.110  -1.129  -0.819  -0.954  -1.026  -0.912  -1.003  -0.984
118   K        -1.597  -1.533  -1.469  -1.601  -1.524  -1.403  -1.331  -1.277  -1.144
119   V         1.277   1.285   1.356   1.248   1.257   1.373   1.390   1.402   1.502
120   T         0.057  -0.026  -0.220   0.093  -0.014  -0.299   0.030  -0.087  -0.380
121   I        -1.201  -1.237  -1.164  -1.120  -1.184  -1.094  -1.121  -1.150  -1.020
122   I        -0.447  -0.472  -0.373  -0.676  -0.725  -0.569  -0.703  -0.739  -0.601
123   P         0.652   0.591   0.441   0.763   0.684   0.446   0.658   0.559   0.269
124   E        -1.597  -1.613  -1.478  -1.531  -1.550  -1.373  -1.331  -1.333  -1.149
125   N        -0.339  -0.327  -0.320  -0.445  -0.437  -0.400  -0.598  -0.585  -0.538
126   L        -1.201  -1.146  -1.152  -1.247  -1.184  -1.149  -1.121  -1.069  -1.010
127   K        -0.216  -0.220  -0.306  -0.246  -0.256  -0.386  -0.389  -0.401  -0.513
128   K        -1.597  -1.569  -1.474  -1.626  -1.590  -1.420  -1.331  -1.303  -1.147
129   L        -0.216  -0.154  -0.284  -0.278  -0.213  -0.374  -0.389  -0.323  -0.481
130   H        -1.884  -1.845  -1.724  -1.805  -1.734  -1.571  -1.435  -1.401  -1.228
131   L        -0.339  -0.357  -0.324  -0.520  -0.550  -0.471  -0.598  -0.622  -0.545
132   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   D        -0.216  -0.194  -0.278  -0.240  -0.197  -0.357  -0.389  -0.347  -0.471
135   L        -0.216  -0.273  -0.307  -0.309  -0.409  -0.450  -0.389  -0.474  -0.512
136   E        -1.884  -1.827  -1.729  -1.717  -1.619  -1.543  -1.435  -1.386  -1.231
137   I         0.180   0.171   0.259  -0.016  -0.042   0.087  -0.180  -0.201  -0.082
138   T        -0.216  -0.273  -0.307  -0.369  -0.466  -0.533  -0.389  -0.474  -0.512
139   C         0.344   0.349   0.332   0.343   0.343   0.315   0.134   0.140   0.061
140   I         0.344   0.349   0.332   0.212   0.214   0.174   0.134   0.140   0.061
141   R         0.344   0.349   0.332   0.381   0.383   0.347   0.134   0.140   0.061
142   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
143   P         1.277   1.285   1.356   1.321   1.336   1.442   1.390   1.402   1.502
144   C         1.277   1.285   1.356   1.441   1.452   1.555   1.390   1.402   1.502
145   H         1.277   1.285   1.356   1.324   1.334   1.445   1.390   1.402   1.502
146   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
147   R         0.344   0.320   0.303   0.473   0.428   0.378   0.134   0.086   0.005
148   D         1.277   1.285   1.356   1.225   1.241   1.351   1.390   1.402   1.502
149   S         1.277   1.285   1.356   1.296   1.317   1.419   1.390   1.402   1.502
150   I         0.652   0.641   0.445   0.736   0.723   0.438   0.658   0.640   0.276
151   C         1.277   1.285   1.356   1.441   1.452   1.555   1.390   1.402   1.502
152   Y         0.057  -0.026  -0.220   0.352   0.249  -0.029   0.030  -0.087  -0.380
153   Y         0.180   0.195   0.268   0.121   0.148   0.238  -0.180  -0.154  -0.064
154   V        -0.504  -0.591  -0.722  -0.336  -0.461  -0.649  -0.494  -0.602  -0.749
155   K        -1.597  -1.621  -1.473  -1.431  -1.449  -1.248  -1.331  -1.340  -1.146
156   D         0.344   0.302   0.311   0.242   0.175   0.164   0.134   0.052   0.020
157   P        -1.201  -1.173  -1.155  -1.170  -1.122  -1.137  -1.121  -1.090  -1.013
158   T        -1.597  -1.620  -1.473  -1.642  -1.666  -1.466  -1.331  -1.339  -1.146
159   T         1.277   1.285   1.356   1.165   1.178   1.295   1.390   1.402   1.502
160   D        -0.932  -0.904  -0.839  -1.119  -1.070  -0.988  -1.021  -0.986  -0.883
161   E         0.057   0.017  -0.209   0.104   0.050  -0.313   0.030  -0.027  -0.364
162   R        -0.339  -0.360  -0.322  -0.394  -0.394  -0.347  -0.598  -0.607  -0.538
163   C        -0.216  -0.235  -0.296  -0.164  -0.197  -0.284  -0.389  -0.412  -0.495
164   I         0.344   0.349   0.332   0.262   0.263   0.218   0.134   0.140   0.061
165   F         1.277   1.285   1.356   1.328   1.342   1.449   1.390   1.402   1.502
166   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
167   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
168   D         1.277   1.285   1.356   1.225   1.241   1.351   1.390   1.402   1.502
169   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
170   L         1.277   1.285   1.356   1.197   1.207   1.324   1.390   1.402   1.502
171   F         1.277   1.285   1.356   1.328   1.342   1.449   1.390   1.402   1.502
172   T        -0.805  -0.846  -0.796  -0.896  -0.949  -0.848  -0.912  -0.942  -0.841
173   A        -0.339  -0.329  -0.316  -0.447  -0.422  -0.394  -0.598  -0.570  -0.530
174   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
175   C         1.277   1.285   1.356   1.441   1.452   1.555   1.390   1.402   1.502
176   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
177   R         1.277   1.285   1.356   1.432   1.443   1.547   1.390   1.402   1.502
178   F         1.277   1.285   1.356   1.328   1.342   1.449   1.390   1.402   1.502
179   F         1.277   1.285   1.356   1.328   1.342   1.449   1.390   1.402   1.502
180   E         1.277   1.285   1.356   1.220   1.233   1.346   1.390   1.402   1.502
181   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
182   T        -0.504  -0.461  -0.695  -0.443  -0.390  -0.728  -0.494  -0.443  -0.716
183   G        -0.216  -0.249  -0.306  -0.248  -0.315  -0.384  -0.389  -0.446  -0.511
184   E        -0.447  -0.460  -0.377  -0.681  -0.706  -0.595  -0.703  -0.722  -0.606
185   E         0.652   0.637   0.448   0.694   0.678   0.437   0.658   0.633   0.281
186   M         1.277   1.285   1.356   1.412   1.434   1.528   1.390   1.402   1.502
187   D        -0.447  -0.452  -0.371  -0.596  -0.606  -0.486  -0.703  -0.710  -0.598
188   I        -1.309  -1.303  -1.178  -1.318  -1.304  -1.121  -1.226  -1.213  -1.034
189   A         0.652   0.716   0.456   0.736   0.811   0.464   0.658   0.755   0.295
190   L         1.277   1.285   1.356   1.197   1.207   1.324   1.390   1.402   1.502
191   N         1.277   1.285   1.356   1.292   1.304   1.414   1.390   1.402   1.502
192   N        -2.171  -2.148  -1.959  -1.956  -1.942  -1.665  -1.540  -1.517  -1.299
193   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   I        -0.339  -0.356  -0.327  -0.485  -0.517  -0.463  -0.598  -0.616  -0.547
195   L         1.277   1.285   1.356   1.197   1.207   1.324   1.390   1.402   1.502
196   E        -0.735  -0.710  -0.765  -0.734  -0.709  -0.784  -0.807  -0.782  -0.802
197   T        -1.201  -1.222  -1.167  -1.279  -1.300  -1.220  -1.121  -1.139  -1.024
198   V         0.344   0.349   0.332   0.199   0.200   0.156   0.134   0.140   0.061
199   G         0.344   0.349   0.332   0.318   0.323   0.261   0.134   0.140   0.061
200   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   S        -0.914  -0.907  -0.811  -1.081  -1.041  -0.912  -1.017  -0.996  -0.854
205   K        -1.201  -1.236  -1.164  -1.248  -1.295  -1.195  -1.121  -1.149  -1.020
206   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
207   R        -0.914  -0.880  -0.813  -1.015  -0.950  -0.854  -1.017  -0.970  -0.857
208   V         0.057  -0.019  -0.222   0.146   0.038  -0.281   0.030  -0.079  -0.383
209   Y         0.652   0.631   0.443   0.856   0.834   0.559   0.658   0.623   0.272
210   P         1.277   1.285   1.356   1.321   1.336   1.442   1.390   1.402   1.502
211   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
212   H         1.277   1.285   1.356   1.324   1.334   1.445   1.390   1.402   1.502
213   E         1.277   1.285   1.356   1.220   1.233   1.346   1.390   1.402   1.502
214   Y         1.277   1.285   1.356   1.396   1.412   1.513   1.390   1.402   1.502
215   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
216   S         0.652   0.673   0.452   0.605   0.642   0.337   0.658   0.689   0.287
217   D         0.652   0.673   0.452   0.742   0.777   0.449   0.658   0.689   0.287
218   N         1.277   1.285   1.356   1.292   1.304   1.414   1.390   1.402   1.502
219   V         0.344   0.324   0.310   0.259   0.216   0.174   0.134   0.093   0.019
220   K         1.277   1.285   1.356   1.150   1.171   1.279   1.390   1.402   1.502
221   F         1.277   1.285   1.356   1.328   1.342   1.449   1.390   1.402   1.502
222   V        -0.805  -0.848  -0.793  -0.810  -0.860  -0.751  -0.912  -0.945  -0.838
223   R        -1.309  -1.283  -1.189  -1.201  -1.152  -1.001  -1.226  -1.197  -1.042
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   K        -0.339  -0.359  -0.331  -0.617  -0.644  -0.572  -0.598  -0.622  -0.552
226   I        -0.216  -0.254  -0.294  -0.216  -0.265  -0.342  -0.389  -0.431  -0.493
227   Y        -0.216  -0.230  -0.292  -0.244  -0.263  -0.337  -0.389  -0.405  -0.488
228   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   E        -1.309  -1.295  -1.182  -1.232  -1.203  -1.053  -1.226  -1.206  -1.037
233   N        -0.216  -0.270  -0.310  -0.222  -0.313  -0.394  -0.389  -0.472  -0.517
234   K        -1.022  -0.967  -1.105  -0.927  -0.843  -1.081  -0.912  -0.850  -0.961
235   A         0.057   0.027  -0.207   0.210   0.166  -0.163   0.030  -0.013  -0.360
236   L        -0.914  -0.883  -0.812  -1.047  -1.005  -0.878  -1.017  -0.974  -0.856
237   D        -0.914  -0.930  -0.825  -1.135  -1.151  -0.991  -1.017  -1.029  -0.870
238   E        -0.805  -0.849  -0.789  -0.966  -1.014  -0.900  -0.912  -0.947  -0.834
239   L         1.277   1.285   1.356   1.197   1.207   1.324   1.390   1.402   1.502
240   E        -1.201  -1.167  -1.153  -1.187  -1.132  -1.097  -1.121  -1.078  -1.010
241   Q        -2.171  -2.148  -1.959  -1.916  -1.880  -1.627  -1.540  -1.517  -1.299
242   F         0.057   0.052  -0.204   0.248   0.233  -0.135   0.030   0.019  -0.356
243   C         0.057   0.124  -0.195   0.348   0.430  -0.045   0.030   0.120  -0.343
244   S        -1.201  -1.195  -1.143  -1.172  -1.158  -1.079  -1.121  -1.108  -1.002
245   K        -1.309  -1.299  -1.179  -1.396  -1.377  -1.187  -1.226  -1.211  -1.035
246   H         0.180   0.192   0.266   0.039   0.055   0.156  -0.180  -0.159  -0.069
247   E        -0.504  -0.576  -0.727  -0.358  -0.453  -0.669  -0.494  -0.584  -0.755
248   V        -1.597  -1.584  -1.474  -1.478  -1.468  -1.301  -1.331  -1.314  -1.147
249   T         0.652   0.591   0.441   0.628   0.551   0.340   0.658   0.559   0.269
250   A        -0.339  -0.347  -0.315  -0.507  -0.516  -0.424  -0.598  -0.601  -0.533
251   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
252   R        -0.735  -0.748  -0.775  -0.771  -0.796  -0.796  -0.807  -0.829  -0.816
253   F         0.652   0.591   0.441   0.782   0.706   0.481   0.658   0.559   0.269
254   T         1.277   1.285   1.356   1.173   1.187   1.302   1.390   1.402   1.502
255   L        -0.216  -0.267  -0.296  -0.218  -0.286  -0.335  -0.389  -0.454  -0.495
256   K         0.057   0.059  -0.217   0.134   0.136  -0.288   0.030   0.033  -0.375
257   D         0.652   0.591   0.441   0.699   0.628   0.431   0.658   0.559   0.269
258   E         1.277   1.285   1.356   1.220   1.233   1.346   1.390   1.402   1.502
259   V        -0.339  -0.297  -0.317  -0.617  -0.543  -0.553  -0.598  -0.533  -0.532
260   E        -0.914  -0.894  -0.815  -1.061  -1.024  -0.900  -1.017  -0.987  -0.860
261   F         0.344   0.336   0.311   0.351   0.334   0.264   0.134   0.115   0.020
262   N         1.277   1.285   1.356   1.292   1.304   1.414   1.390   1.402   1.502
263   P         0.652   0.631   0.443   0.770   0.745   0.466   0.658   0.623   0.272
264   F         1.277   1.285   1.356   1.328   1.342   1.449   1.390   1.402   1.502
265   M         1.277   1.285   1.356   1.412   1.434   1.528   1.390   1.402   1.502
266   R        -0.735  -0.730  -0.757  -0.557  -0.539  -0.594  -0.807  -0.794  -0.797
267   L        -0.216  -0.264  -0.308  -0.302  -0.385  -0.442  -0.389  -0.459  -0.516
268   E        -1.597  -1.605  -1.473  -1.593  -1.611  -1.416  -1.331  -1.328  -1.146
269   D         0.652   0.637   0.448   0.666   0.651   0.369   0.658   0.633   0.281
270   P         0.652   0.637   0.448   0.766   0.750   0.465   0.658   0.633   0.281
271   K        -1.884  -1.824  -1.725  -1.752  -1.668  -1.529  -1.435  -1.384  -1.228
272   V         0.057  -0.026  -0.220   0.150   0.031  -0.269   0.030  -0.087  -0.380
273   Q        -0.504  -0.465  -0.696  -0.176  -0.128  -0.483  -0.494  -0.444  -0.719
274   K        -0.504  -0.465  -0.696  -0.471  -0.415  -0.759  -0.494  -0.444  -0.719
275   A        -1.022  -0.955  -1.109  -0.829  -0.746  -0.981  -0.912  -0.840  -0.965
276   A        -1.201  -1.229  -1.163  -1.222  -1.274  -1.140  -1.121  -1.144  -1.020
277   G         1.277   1.285   1.356   1.241   1.252   1.366   1.390   1.402   1.502
278   D        -1.309  -1.273  -1.182  -1.399  -1.354  -1.203  -1.226  -1.192  -1.037
279   T        -0.339  -0.372  -0.319  -0.525  -0.557  -0.463  -0.598  -0.627  -0.538
280   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   D         0.057   0.099  -0.195   0.124   0.182  -0.253   0.030   0.088  -0.343
285   R        -0.216  -0.163  -0.289  -0.145  -0.060  -0.249  -0.389  -0.307  -0.487
286   A        -0.914  -0.894  -0.825  -1.009  -1.000  -0.881  -1.017  -1.001  -0.871
287   Q        -1.309  -1.293  -1.180  -1.410  -1.391  -1.201  -1.226  -1.204  -1.035
288   I         0.180   0.198   0.268  -0.030  -0.003   0.099  -0.180  -0.147  -0.064
289   M         1.277   1.285   1.356   1.412   1.434   1.528   1.390   1.402   1.502
290   D        -1.022  -0.984  -1.107  -0.974  -0.921  -1.159  -0.912  -0.870  -0.963
291   K         0.057   0.001  -0.216   0.049  -0.022  -0.356   0.030  -0.051  -0.374
292   L         1.277   1.285   1.356   1.197   1.207   1.324   1.390   1.402   1.502
293   R         1.277   1.285   1.356   1.432   1.443   1.547   1.390   1.402   1.502
294   A        -1.201  -1.212  -1.157  -1.302  -1.325  -1.249  -1.121  -1.126  -1.014
295   M         0.057   0.001  -0.216   0.336   0.266  -0.073   0.030  -0.051  -0.374
296   K         1.277   1.285   1.356   1.150   1.171   1.279   1.390   1.402   1.502
297   N         1.277   1.285   1.356   1.292   1.304   1.414   1.390   1.402   1.502
298   R        -1.201  -1.229  -1.163  -1.083  -1.126  -1.015  -1.121  -1.144  -1.020
299   M        -1.022  -1.098  -1.137  -0.730  -0.846  -0.967  -0.912  -0.991  -0.992
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q05584
Output conservation file - output/Q05584
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
