1     M         1.212   1.228   1.296   1.412   1.437   1.532   1.296   1.319   1.418
2     S        -0.596  -0.494  -0.539  -0.659  -0.519  -0.555  -0.809  -0.685  -0.687
3     E        -1.444  -1.460  -1.436  -1.320  -1.366  -1.350  -1.230  -1.240  -1.158
4     K        -1.936  -1.847  -1.765  -1.889  -1.757  -1.644  -1.511  -1.427  -1.282
5     S        -1.187  -1.222  -1.085  -1.295  -1.340  -1.134  -1.180  -1.208  -1.021
6     A        -1.686  -1.615  -1.473  -1.579  -1.470  -1.276  -1.455  -1.381  -1.188
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.285  -1.223  -1.089  -1.504  -1.417  -1.206  -1.283  -1.211  -1.025
11    -        -0.688  -0.607  -0.574  -0.920  -0.763  -0.732  -0.905  -0.794  -0.729
12    -        -1.599  -1.598  -1.462  -1.608  -1.608  -1.404  -1.379  -1.366  -1.179
13    -        -1.025  -1.021  -1.039  -0.953  -0.944  -0.973  -0.997  -0.990  -0.974
14    -        -0.350  -0.423  -0.526  -0.392  -0.499  -0.668  -0.423  -0.524  -0.663
15    -        -1.183  -1.131  -1.067  -1.306  -1.211  -1.121  -1.188  -1.123  -1.004
16    -        -0.350  -0.423  -0.526  -0.221  -0.326  -0.483  -0.423  -0.524  -0.663
17    S        -0.509  -0.547  -0.549  -0.493  -0.571  -0.582  -0.669  -0.729  -0.699
18    N        -1.088  -1.046  -1.045  -1.109  -1.068  -1.037  -1.090  -1.050  -0.983
19    N        -1.088  -1.018  -1.036  -1.213  -1.093  -1.123  -1.090  -1.002  -0.973
20    K        -1.088  -1.049  -1.036  -1.118  -1.079  -1.043  -1.090  -1.043  -0.974
21    A         0.474   0.356   0.241   0.588   0.428   0.250   0.454   0.265   0.042
22    E        -1.088  -0.965  -1.031  -1.079  -0.899  -0.973  -1.090  -0.941  -0.968
23    F        -0.018   0.033   0.118  -0.220  -0.132  -0.007  -0.388  -0.302  -0.185
24    K         0.135   0.117   0.136  -0.037  -0.068  -0.057  -0.108  -0.146  -0.151
25    R         0.474   0.584   0.267   0.539   0.678   0.220   0.454   0.616   0.088
26    Q        -0.222  -0.036  -0.434   0.060   0.305  -0.300  -0.248   0.002  -0.538
27    S        -1.088  -0.953  -1.032  -1.076  -0.906  -0.979  -1.090  -0.951  -0.971
28    S         1.212   1.228   1.296   1.221   1.254   1.353   1.296   1.319   1.418
29    P        -1.444  -1.399  -1.421  -1.246  -1.183  -1.230  -1.230  -1.186  -1.145
30    F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
31    R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
32    E        -0.596  -0.570  -0.544  -0.790  -0.735  -0.679  -0.809  -0.767  -0.694
33    I        -0.866  -0.996  -1.022  -0.701  -0.907  -0.962  -0.809  -0.959  -0.956
34    I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
35    S         1.212   1.228   1.296   1.221   1.254   1.353   1.296   1.319   1.418
36    A        -1.444  -1.445  -1.429  -1.265  -1.272  -1.267  -1.230  -1.228  -1.151
37    D        -1.579  -1.592  -1.455  -1.562  -1.588  -1.390  -1.371  -1.362  -1.174
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -         0.000   0.096   0.138  -0.234  -0.059  -0.015  -0.355  -0.185  -0.147
40    H        -1.222  -1.171  -1.068  -1.238  -1.138  -0.995  -1.230  -1.164  -1.005
41    P        -1.088  -1.128  -1.044  -1.044  -1.101  -0.996  -1.090  -1.115  -0.982
42    I        -1.936  -1.924  -1.775  -1.844  -1.848  -1.633  -1.511  -1.487  -1.289
43    Y         0.474   0.356   0.241   0.563   0.406   0.218   0.454   0.265   0.042
44    K        -1.088  -1.025  -1.037  -1.069  -0.994  -0.977  -1.090  -1.023  -0.975
45    P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
46    A        -0.222  -0.367  -0.486  -0.156  -0.359  -0.545  -0.248  -0.448  -0.608
47    K        -0.509  -0.320  -0.494  -0.666  -0.361  -0.616  -0.669  -0.404  -0.621
48    G        -0.731  -0.662  -0.565  -0.900  -0.790  -0.650  -0.950  -0.858  -0.717
49    R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
50    Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
51    W         0.474   0.356   0.241   0.666   0.518   0.344   0.454   0.265   0.042
52    L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
53    Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
54    V         1.212   1.228   1.296   1.184   1.204   1.318   1.296   1.319   1.418
55    A         0.474   0.356   0.241   0.573   0.424   0.237   0.454   0.265   0.042
56    L        -1.222  -1.125  -1.064  -1.222  -1.127  -1.008  -1.230  -1.127  -1.002
57    P         0.474   0.356   0.241   0.615   0.450   0.263   0.454   0.265   0.042
58    C         1.212   1.228   1.296   1.437   1.457   1.555   1.296   1.319   1.418
59    P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
60    W         1.212   1.228   1.296   1.378   1.400   1.500   1.296   1.319   1.418
61    A         1.212   1.228   1.296   1.271   1.291   1.400   1.296   1.319   1.418
62    Q        -0.222  -0.333  -0.481   0.027  -0.121  -0.356  -0.248  -0.402  -0.602
63    R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
64    T        -0.222  -0.261  -0.474  -0.081  -0.141  -0.464  -0.248  -0.301  -0.592
65    L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
66    I         0.474   0.584   0.267   0.509   0.651   0.224   0.454   0.616   0.088
67    T         0.135   0.137   0.138   0.040   0.032   0.005  -0.108  -0.111  -0.147
68    R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
69    A        -1.088  -1.026  -1.033  -1.151  -1.046  -1.042  -1.090  -1.008  -0.969
70    L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
71    K         1.212   1.228   1.296   1.122   1.154   1.260   1.296   1.319   1.418
72    G         1.212   1.228   1.296   1.237   1.257   1.367   1.296   1.319   1.418
73    L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
74    A        -0.596  -0.630  -0.547  -0.747  -0.776  -0.637  -0.809  -0.824  -0.696
75    P        -1.579  -1.549  -1.454  -1.419  -1.404  -1.263  -1.371  -1.328  -1.173
76    I        -0.222  -0.271  -0.466  -0.173  -0.241  -0.568  -0.248  -0.314  -0.581
77    I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
78    G        -1.088  -1.114  -1.049  -1.052  -1.093  -0.991  -1.090  -1.108  -0.987
79    C        -1.088  -1.136  -1.052  -1.100  -1.146  -1.011  -1.090  -1.126  -0.990
80    S        -0.222  -0.271  -0.466  -0.072  -0.128  -0.440  -0.248  -0.314  -0.581
81    V         0.474   0.478   0.252   0.527   0.534   0.204   0.454   0.459   0.061
82    A         0.474   0.356   0.241   0.536   0.376   0.204   0.454   0.265   0.042
83    H        -0.222  -0.271  -0.466  -0.006  -0.075  -0.395  -0.248  -0.314  -0.581
84    W         1.212   1.228   1.296   1.378   1.400   1.500   1.296   1.319   1.418
85    H        -0.222  -0.271  -0.466  -0.027  -0.094  -0.434  -0.248  -0.314  -0.581
86    L         0.474   0.356   0.241   0.733   0.566   0.338   0.454   0.265   0.042
87    D         0.135   0.137   0.138   0.035   0.027   0.013  -0.108  -0.111  -0.147
88    D        -1.222  -1.193  -1.068  -1.337  -1.290  -1.102  -1.230  -1.185  -1.006
89    K        -1.088  -1.109  -1.050  -1.201  -1.230  -1.155  -1.090  -1.102  -0.988
90    G         1.212   1.228   1.296   1.237   1.257   1.367   1.296   1.319   1.418
91    W         1.212   1.228   1.296   1.378   1.400   1.500   1.296   1.319   1.418
92    R        -0.222  -0.271  -0.466  -0.115  -0.188  -0.514  -0.248  -0.314  -0.581
93    F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
94    L        -1.579  -1.606  -1.454  -1.429  -1.505  -1.295  -1.371  -1.373  -1.173
95    E        -1.936  -1.932  -1.784  -1.907  -1.917  -1.705  -1.511  -1.492  -1.295
96    E        -0.596  -0.549  -0.539  -0.815  -0.718  -0.676  -0.809  -0.732  -0.685
97    G        -0.350  -0.485  -0.521  -0.352  -0.555  -0.628  -0.423  -0.611  -0.656
98    D         0.311   0.185   0.176   0.244   0.044   0.015   0.195  -0.025  -0.076
99    G        -0.688  -0.583  -0.567  -0.828  -0.667  -0.659  -0.905  -0.762  -0.719
100   K         0.000   0.110   0.147  -0.289  -0.086  -0.050  -0.355  -0.160  -0.130
101   T        -0.036   0.019   0.116  -0.351  -0.239  -0.090  -0.423  -0.329  -0.187
102   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   N        -1.187  -1.206  -1.085  -1.307  -1.355  -1.193  -1.180  -1.196  -1.021
130   N        -1.187  -1.206  -1.085  -1.265  -1.295  -1.135  -1.180  -1.196  -1.021
131   A        -1.187  -1.206  -1.085  -1.187  -1.225  -1.040  -1.180  -1.196  -1.021
132   H        -1.686  -1.601  -1.473  -1.730  -1.564  -1.418  -1.455  -1.369  -1.188
133   R        -1.187  -1.206  -1.085  -1.203  -1.247  -1.059  -1.180  -1.196  -1.021
134   L        -0.499  -0.633  -0.568  -0.532  -0.778  -0.685  -0.630  -0.816  -0.719
135   L        -1.025  -1.145  -1.066  -1.043  -1.254  -1.136  -0.997  -1.126  -1.002
136   V        -1.599  -1.605  -1.470  -1.629  -1.638  -1.422  -1.379  -1.373  -1.185
137   D        -1.579  -1.511  -1.450  -1.526  -1.414  -1.319  -1.371  -1.294  -1.169
138   G        -0.866  -0.911  -1.015  -0.636  -0.700  -0.858  -0.809  -0.857  -0.949
139   T         0.474   0.478   0.252   0.552   0.557   0.217   0.454   0.459   0.061
140   D        -1.088  -1.099  -1.039  -1.108  -1.111  -1.025  -1.090  -1.079  -0.975
141   E         0.474   0.356   0.241   0.518   0.350   0.157   0.454   0.265   0.042
142   P        -0.596  -0.577  -0.543  -0.639  -0.606  -0.546  -0.809  -0.764  -0.691
143   H        -1.088  -1.092  -1.051  -1.179  -1.177  -1.094  -1.090  -1.093  -0.989
144   Y        -0.866  -0.805  -0.990  -0.679  -0.609  -0.880  -0.809  -0.739  -0.921
145   G        -0.509  -0.445  -0.527  -0.543  -0.472  -0.587  -0.669  -0.603  -0.670
146   Y        -1.444  -1.536  -1.453  -1.279  -1.426  -1.322  -1.230  -1.309  -1.171
147   K        -1.936  -1.932  -1.784  -1.774  -1.792  -1.560  -1.511  -1.492  -1.295
148   R         0.135   0.137   0.138   0.054   0.045   0.026  -0.108  -0.111  -0.147
149   L        -1.088  -0.996  -1.032  -1.147  -1.011  -1.022  -1.090  -0.984  -0.970
150   S        -0.509  -0.503  -0.509  -0.581  -0.540  -0.577  -0.669  -0.636  -0.642
151   D        -1.088  -1.099  -1.039  -1.060  -1.083  -0.994  -1.090  -1.079  -0.975
152   F        -0.866  -0.989  -1.025  -0.844  -1.028  -1.095  -0.809  -0.951  -0.959
153   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
154   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
155   K        -0.222  -0.235  -0.473  -0.174  -0.185  -0.541  -0.248  -0.264  -0.591
156   T        -0.509  -0.605  -0.548  -0.501  -0.662  -0.584  -0.669  -0.787  -0.697
157   K        -1.088  -1.149  -1.052  -1.175  -1.268  -1.132  -1.090  -1.137  -0.990
158   P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
159   D        -0.222  -0.342  -0.485  -0.176  -0.347  -0.584  -0.248  -0.414  -0.608
160   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
161   K        -1.936  -1.843  -1.769  -1.845  -1.725  -1.614  -1.511  -1.427  -1.284
162   G        -0.222  -0.235  -0.473  -0.015  -0.033  -0.358  -0.248  -0.264  -0.591
163   R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
164   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
165   T         1.212   1.228   1.296   1.215   1.236   1.347   1.296   1.319   1.418
166   V         1.212   1.228   1.296   1.184   1.204   1.318   1.296   1.319   1.418
167   P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
168   V         0.474   0.437   0.249   0.506   0.455   0.151   0.454   0.395   0.056
169   L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
170   W         0.135   0.122   0.136   0.207   0.175   0.150  -0.108  -0.138  -0.151
171   D         1.212   1.228   1.296   1.188   1.208   1.322   1.296   1.319   1.418
172   L        -0.222  -0.342  -0.485  -0.201  -0.371  -0.616  -0.248  -0.414  -0.608
173   E         0.474   0.356   0.241   0.451   0.297   0.098   0.454   0.265   0.042
174   T        -1.579  -1.606  -1.454  -1.577  -1.588  -1.348  -1.371  -1.373  -1.173
175   C        -1.088  -1.099  -1.039  -1.045  -1.017  -0.939  -1.090  -1.079  -0.975
176   T        -0.222  -0.261  -0.474  -0.105  -0.165  -0.511  -0.248  -0.301  -0.592
177   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
178   V         1.212   1.228   1.296   1.184   1.204   1.318   1.296   1.319   1.418
179   N         0.474   0.437   0.249   0.516   0.484   0.189   0.454   0.395   0.056
180   N         1.212   1.228   1.296   1.173   1.208   1.307   1.296   1.319   1.418
181   E         1.212   1.228   1.296   1.138   1.165   1.274   1.296   1.319   1.418
182   S         1.212   1.228   1.296   1.221   1.254   1.353   1.296   1.319   1.418
183   S        -0.018   0.007   0.108  -0.190  -0.148   0.004  -0.388  -0.351  -0.203
184   D         0.474   0.356   0.241   0.476   0.317   0.131   0.454   0.265   0.042
185   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
186   I        -0.509  -0.405  -0.499  -0.653  -0.462  -0.630  -0.669  -0.510  -0.627
187   G         0.474   0.356   0.241   0.558   0.394   0.216   0.454   0.265   0.042
188   I        -0.222  -0.367  -0.486   0.097  -0.120  -0.356  -0.248  -0.448  -0.608
189   M        -0.509  -0.562  -0.533  -0.600  -0.644  -0.591  -0.669  -0.723  -0.678
190   N        -0.866  -0.822  -0.991  -0.719  -0.656  -0.904  -0.809  -0.757  -0.922
191   S        -0.509  -0.493  -0.525  -0.538  -0.506  -0.572  -0.669  -0.640  -0.667
192   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   A         0.135   0.080   0.125   0.000  -0.096  -0.030  -0.108  -0.216  -0.170
194   F         0.474   0.437   0.249   0.594   0.556   0.302   0.454   0.395   0.056
195   D         0.135   0.068   0.120   0.002  -0.118  -0.061  -0.108  -0.237  -0.181
196   E        -0.018  -0.009   0.104  -0.272  -0.267  -0.093  -0.388  -0.382  -0.210
197   F        -1.088  -1.133  -1.050  -1.214  -1.267  -1.137  -1.090  -1.121  -0.989
198   V        -0.731  -0.732  -0.593  -1.023  -1.020  -0.800  -0.950  -0.948  -0.753
199   G        -1.088  -1.073  -1.045  -1.099  -1.098  -1.031  -1.090  -1.074  -0.983
200   E        -0.731  -0.729  -0.592  -0.930  -0.943  -0.735  -0.950  -0.944  -0.752
201   E        -0.222  -0.261  -0.474  -0.170  -0.222  -0.552  -0.248  -0.301  -0.592
202   Y        -0.222  -0.235  -0.473  -0.109  -0.129  -0.529  -0.248  -0.264  -0.591
203   R        -0.350  -0.485  -0.521  -0.233  -0.454  -0.547  -0.423  -0.611  -0.656
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   Q        -0.866  -0.996  -1.022  -0.725  -0.900  -0.930  -0.809  -0.959  -0.956
206   V        -0.018   0.045   0.119  -0.331  -0.211  -0.110  -0.388  -0.279  -0.182
207   R         0.474   0.356   0.241   0.530   0.365   0.186   0.454   0.265   0.042
208   L         0.474   0.437   0.249   0.437   0.398   0.120   0.454   0.395   0.056
209   V         0.135   0.123   0.134   0.050   0.018   0.007  -0.108  -0.136  -0.153
210   P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
211   R        -1.088  -1.152  -1.061  -1.192  -1.279  -1.131  -1.090  -1.145  -0.999
212   S        -1.088  -1.058  -1.041  -1.137  -1.106  -1.080  -1.090  -1.062  -0.980
213   L        -0.222  -0.013  -0.444  -0.185   0.087  -0.487  -0.248   0.032  -0.552
214   E         0.135   0.123   0.134   0.020  -0.013  -0.028  -0.108  -0.136  -0.153
215   A        -1.936  -1.799  -1.761  -1.710  -1.514  -1.478  -1.511  -1.387  -1.279
216   Q        -1.088  -1.016  -1.033  -1.051  -0.961  -0.958  -1.090  -1.016  -0.972
217   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
218   T         0.474   0.356   0.241   0.531   0.366   0.187   0.454   0.265   0.042
219   E         0.474   0.437   0.249   0.490   0.449   0.177   0.454   0.395   0.056
220   F        -1.222  -1.219  -1.070  -1.406  -1.380  -1.158  -1.230  -1.207  -1.007
221   N         1.212   1.228   1.296   1.173   1.208   1.307   1.296   1.319   1.418
222   S        -0.509  -0.527  -0.541  -0.573  -0.606  -0.644  -0.669  -0.694  -0.689
223   W         0.474   0.468   0.251   0.721   0.713   0.374   0.454   0.443   0.059
224   V        -0.509  -0.552  -0.549  -0.603  -0.685  -0.665  -0.669  -0.734  -0.699
225   Y         0.474   0.584   0.267   0.582   0.716   0.293   0.454   0.616   0.088
226   D        -0.222  -0.261  -0.474  -0.104  -0.161  -0.480  -0.248  -0.301  -0.592
227   K        -1.088  -1.152  -1.061  -1.147  -1.248  -1.110  -1.090  -1.145  -0.999
228   I         0.474   0.468   0.251   0.495   0.493   0.164   0.454   0.443   0.059
229   N         1.212   1.228   1.296   1.173   1.208   1.307   1.296   1.319   1.418
230   N         0.474   0.584   0.267   0.516   0.668   0.220   0.454   0.616   0.088
231   G         1.212   1.228   1.296   1.237   1.257   1.367   1.296   1.319   1.418
232   V         1.212   1.228   1.296   1.184   1.204   1.318   1.296   1.319   1.418
233   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
234   K         1.212   1.228   1.296   1.122   1.154   1.260   1.296   1.319   1.418
235   A        -0.731  -0.725  -0.592  -0.850  -0.845  -0.642  -0.950  -0.939  -0.752
236   G         1.212   1.228   1.296   1.237   1.257   1.367   1.296   1.319   1.418
237   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
238   A         0.135   0.269   0.200   0.107   0.323   0.189  -0.108   0.120  -0.032
239   E        -0.222  -0.244  -0.467  -0.100  -0.150  -0.491  -0.248  -0.289  -0.583
240   C        -0.596  -0.630  -0.547  -0.716  -0.712  -0.567  -0.809  -0.824  -0.696
241   A         0.135   0.080   0.125   0.230   0.116   0.159  -0.108  -0.216  -0.170
242   E         1.212   1.228   1.296   1.138   1.165   1.274   1.296   1.319   1.418
243   V        -0.596  -0.507  -0.540  -0.700  -0.585  -0.601  -0.809  -0.708  -0.691
244   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
245   E        -0.596  -0.501  -0.542  -0.766  -0.645  -0.647  -0.809  -0.695  -0.692
246   R        -0.509  -0.573  -0.548  -0.584  -0.680  -0.605  -0.669  -0.757  -0.698
247   E        -0.018  -0.004   0.104  -0.320  -0.294  -0.126  -0.388  -0.373  -0.210
248   V         0.474   0.581   0.264   0.564   0.688   0.304   0.454   0.611   0.083
249   T        -2.292  -2.215  -2.052  -1.994  -1.918  -1.665  -1.651  -1.581  -1.374
250   S        -1.444  -1.536  -1.453  -1.299  -1.428  -1.319  -1.230  -1.309  -1.171
251   L        -0.018  -0.009   0.104  -0.331  -0.336  -0.150  -0.388  -0.382  -0.210
252   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
253   Q        -1.579  -1.511  -1.450  -1.484  -1.357  -1.308  -1.371  -1.294  -1.169
254   Y        -1.088  -1.164  -1.062  -0.988  -1.107  -0.962  -1.090  -1.155  -1.000
255   L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
256   D         1.212   1.228   1.296   1.188   1.208   1.322   1.296   1.319   1.418
257   K        -0.509  -0.442  -0.521  -0.577  -0.507  -0.559  -0.669  -0.600  -0.662
258   L         0.135   0.080   0.125  -0.024  -0.141  -0.096  -0.108  -0.216  -0.170
259   E         1.212   1.228   1.296   1.138   1.165   1.274   1.296   1.319   1.418
260   N        -1.579  -1.502  -1.443  -1.487  -1.396  -1.300  -1.371  -1.296  -1.165
261   L        -0.866  -0.968  -1.028  -0.777  -0.942  -1.043  -0.809  -0.927  -0.962
262   L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
263   D        -1.579  -1.561  -1.455  -1.556  -1.542  -1.383  -1.371  -1.339  -1.173
264   K        -0.018  -0.004   0.104  -0.355  -0.332  -0.161  -0.388  -0.373  -0.210
265   K        -1.444  -1.536  -1.453  -1.326  -1.467  -1.357  -1.230  -1.309  -1.171
266   Y        -1.088  -1.093  -1.034  -1.052  -1.048  -0.939  -1.090  -1.074  -0.971
267   T        -0.660  -0.690  -0.589  -0.847  -0.899  -0.752  -0.853  -0.896  -0.748
268   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   G        -0.499  -0.456  -0.527  -0.516  -0.468  -0.604  -0.630  -0.577  -0.665
275   K        -1.187  -0.978  -1.056  -1.282  -0.959  -1.085  -1.180  -0.936  -0.992
276   N        -0.499  -0.480  -0.541  -0.555  -0.513  -0.656  -0.630  -0.607  -0.684
277   N         0.199   0.146   0.162   0.068  -0.018  -0.015   0.006  -0.094  -0.102
278   K        -0.499  -0.504  -0.530  -0.524  -0.542  -0.618  -0.630  -0.639  -0.669
279   D        -1.025  -1.056  -1.037  -1.022  -1.085  -1.051  -0.997  -1.034  -0.972
280   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   F         0.474   0.437   0.249   0.563   0.519   0.232   0.454   0.395   0.056
287   A        -0.222  -0.333  -0.481  -0.162  -0.308  -0.498  -0.248  -0.402  -0.602
288   I        -1.088  -1.108  -1.041  -1.214  -1.240  -1.124  -1.090  -1.102  -0.980
289   G         0.474   0.605   0.267   0.574   0.736   0.265   0.454   0.646   0.089
290   D        -0.018   0.077   0.138  -0.278  -0.103  -0.022  -0.388  -0.221  -0.147
291   T        -1.579  -1.497  -1.444  -1.482  -1.359  -1.247  -1.371  -1.281  -1.165
292   L         0.474   0.605   0.267   0.426   0.599   0.126   0.454   0.646   0.089
293   T         1.212   1.228   1.296   1.215   1.236   1.347   1.296   1.319   1.418
294   E         1.212   1.228   1.296   1.138   1.165   1.274   1.296   1.319   1.418
295   A        -0.222  -0.235  -0.473  -0.037  -0.060  -0.438  -0.248  -0.264  -0.591
296   D         1.212   1.228   1.296   1.188   1.208   1.322   1.296   1.319   1.418
297   V        -0.018  -0.009   0.104  -0.296  -0.290  -0.104  -0.388  -0.382  -0.210
298   R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
299   L         1.212   1.228   1.296   1.093   1.123   1.232   1.296   1.319   1.418
300   Y        -0.018  -0.004   0.104  -0.220  -0.205  -0.033  -0.388  -0.372  -0.210
301   P         0.135   0.084   0.124   0.055  -0.048   0.000  -0.108  -0.208  -0.173
302   T         1.212   1.228   1.296   1.215   1.236   1.347   1.296   1.319   1.418
303   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
304   V         0.135   0.193   0.147   0.001   0.094  -0.015  -0.108  -0.011  -0.130
305   R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
306   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
307   D         1.212   1.228   1.296   1.188   1.208   1.322   1.296   1.319   1.418
308   V        -0.509  -0.503  -0.509  -0.511  -0.495  -0.515  -0.669  -0.636  -0.642
309   V         1.212   1.228   1.296   1.184   1.204   1.318   1.296   1.319   1.418
310   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
311   H         0.474   0.356   0.241   0.540   0.384   0.215   0.454   0.265   0.042
312   Q         0.474   0.437   0.249   0.755   0.709   0.442   0.454   0.395   0.056
313   H         1.212   1.228   1.296   1.297   1.324   1.424   1.296   1.319   1.418
314   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
315   K         1.212   1.228   1.296   1.122   1.154   1.260   1.296   1.319   1.418
316   C         1.212   1.228   1.296   1.437   1.457   1.555   1.296   1.319   1.418
317   N         1.212   1.228   1.296   1.173   1.208   1.307   1.296   1.319   1.418
318   L         0.135   0.187   0.148  -0.087   0.005  -0.088  -0.108  -0.022  -0.127
319   A        -1.088  -1.092  -1.037  -1.090  -1.070  -0.994  -1.090  -1.073  -0.972
320   T        -0.596  -0.570  -0.544  -0.569  -0.542  -0.492  -0.809  -0.767  -0.694
321   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
322   R         1.212   1.228   1.296   1.213   1.231   1.345   1.296   1.319   1.418
323   D        -1.579  -1.544  -1.451  -1.449  -1.400  -1.268  -1.371  -1.325  -1.170
324   D        -0.866  -0.801  -0.995  -0.715  -0.635  -0.916  -0.809  -0.731  -0.926
325   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
326   S         0.474   0.356   0.241   0.567   0.404   0.220   0.454   0.265   0.042
327   R        -1.444  -1.460  -1.436  -1.271  -1.300  -1.259  -1.230  -1.240  -1.158
328   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
329   H         0.474   0.468   0.251   0.632   0.631   0.284   0.454   0.443   0.059
330   T        -1.579  -1.548  -1.450  -1.508  -1.451  -1.306  -1.371  -1.328  -1.170
331   W         1.212   1.228   1.296   1.378   1.400   1.500   1.296   1.319   1.418
332   L         0.474   0.478   0.252   0.470   0.486   0.197   0.454   0.459   0.061
333   K         0.135   0.080   0.125   0.015  -0.102  -0.056  -0.108  -0.216  -0.170
334   N        -1.936  -1.931  -1.777  -1.849  -1.839  -1.605  -1.511  -1.491  -1.290
335   I         0.474   0.356   0.241   0.426   0.270   0.080   0.454   0.265   0.042
336   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
337   W         1.212   1.228   1.296   1.378   1.400   1.500   1.296   1.319   1.418
338   R        -0.866  -0.989  -1.025  -0.812  -0.996  -1.068  -0.809  -0.951  -0.959
339   H        -0.509  -0.547  -0.549  -0.559  -0.620  -0.612  -0.669  -0.729  -0.699
340   E         0.474   0.356   0.241   0.553   0.384   0.188   0.454   0.265   0.042
341   A        -0.018   0.077   0.138  -0.170  -0.004   0.078  -0.388  -0.221  -0.147
342   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
343   Q        -1.579  -1.509  -1.441  -1.440  -1.331  -1.241  -1.371  -1.298  -1.163
344   R        -0.222  -0.367  -0.486  -0.168  -0.377  -0.569  -0.248  -0.448  -0.608
345   T         1.212   1.228   1.296   1.215   1.236   1.347   1.296   1.319   1.418
346   T         1.212   1.228   1.296   1.215   1.236   1.347   1.296   1.319   1.418
347   D        -0.018   0.009   0.107  -0.278  -0.234  -0.084  -0.388  -0.348  -0.205
348   F         1.212   1.228   1.296   1.219   1.245   1.351   1.296   1.319   1.418
349   T        -1.936  -1.875  -1.770  -1.884  -1.811  -1.648  -1.511  -1.451  -1.285
350   H         1.212   1.228   1.296   1.297   1.324   1.424   1.296   1.319   1.418
351   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
352   K         1.212   1.228   1.296   1.122   1.154   1.260   1.296   1.319   1.418
353   L        -1.222  -1.220  -1.071  -1.226  -1.240  -1.009  -1.230  -1.208  -1.009
354   G         0.474   0.356   0.241   0.642   0.485   0.290   0.454   0.265   0.042
355   Y         1.212   1.228   1.296   1.226   1.247   1.357   1.296   1.319   1.418
356   T         0.474   0.437   0.249   0.590   0.547   0.298   0.454   0.395   0.056
357   R        -1.444  -1.536  -1.453  -1.259  -1.387  -1.230  -1.230  -1.309  -1.171
358   S         1.212   1.228   1.296   1.221   1.254   1.353   1.296   1.319   1.418
359   Q         0.474   0.356   0.241   0.666   0.519   0.345   0.454   0.265   0.042
360   P        -1.444  -1.335  -1.400  -1.333  -1.184  -1.310  -1.230  -1.116  -1.126
361   R        -1.222  -1.221  -1.071  -1.219  -1.207  -0.990  -1.230  -1.209  -1.008
362   V        -0.222  -0.367  -0.486  -0.115  -0.317  -0.485  -0.248  -0.448  -0.608
363   N         1.212   1.228   1.296   1.173   1.208   1.307   1.296   1.319   1.418
364   P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
365   I        -1.579  -1.592  -1.455  -1.619  -1.635  -1.453  -1.371  -1.362  -1.174
366   G         0.474   0.437   0.249   0.607   0.561   0.306   0.454   0.395   0.056
367   I         1.212   1.228   1.296   1.158   1.186   1.293   1.296   1.319   1.418
368   T         0.474   0.437   0.249   0.552   0.502   0.212   0.454   0.395   0.056
369   P         0.474   0.437   0.249   0.575   0.525   0.253   0.454   0.395   0.056
370   L         0.474   0.437   0.249   0.445   0.407   0.138   0.454   0.395   0.056
371   G         1.212   1.228   1.296   1.237   1.257   1.367   1.296   1.319   1.418
372   P         1.212   1.228   1.296   1.224   1.242   1.355   1.296   1.319   1.418
373   K        -0.509  -0.561  -0.545  -0.622  -0.731  -0.703  -0.669  -0.748  -0.695
374   P         0.474   0.437   0.249   0.553   0.501   0.203   0.454   0.395   0.056
375   D        -0.018  -0.001   0.104  -0.281  -0.254  -0.090  -0.388  -0.366  -0.210
376   I         0.135   0.199   0.146  -0.014   0.092  -0.024  -0.108  -0.000  -0.131
377   R        -0.222  -0.342  -0.485  -0.223  -0.391  -0.625  -0.248  -0.414  -0.608
378   P        -0.866  -0.696  -0.984  -0.684  -0.460  -0.877  -0.809  -0.609  -0.915
379   P        -1.579  -1.606  -1.454  -1.607  -1.645  -1.423  -1.371  -1.373  -1.173
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -0.660  -0.636  -0.569  -0.852  -0.814  -0.713  -0.853  -0.818  -0.721
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04806
Output conservation file - output/Q04806
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
