1     M         2.224   2.227   2.259   2.669   2.674   2.727   2.450   2.454   2.499
2     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S         0.217   0.218   0.238   0.055   0.056   0.088  -0.029  -0.027   0.003
6     A         0.217   0.218   0.238   0.603   0.605   0.641  -0.029  -0.027   0.003
7     S         0.217   0.218   0.238   0.231   0.231   0.264  -0.029  -0.027   0.003
8     I         0.217   0.218   0.238   0.316   0.317   0.351  -0.029  -0.027   0.003
9     K         0.217   0.218   0.238  -0.073  -0.073  -0.042  -0.029  -0.027   0.003
10    D         0.217   0.218   0.238  -0.065  -0.065  -0.034  -0.029  -0.027   0.003
11    Y         2.224   2.227   2.259   2.590   2.594   2.647   2.450   2.454   2.499
12    E         0.381   0.357   0.346   0.231   0.198   0.192   0.247   0.208   0.186
13    T        -0.957  -0.956  -0.945  -0.713  -0.720  -0.688  -0.855  -0.852  -0.829
14    V        -0.957  -0.956  -0.945  -1.003  -1.014  -0.982  -0.855  -0.852  -0.829
15    L         0.381   0.357   0.346   0.117   0.090   0.073   0.247   0.208   0.186
16    T        -0.957  -0.956  -0.945  -0.817  -0.831  -0.793  -0.855  -0.852  -0.829
17    D        -0.957  -0.956  -0.945  -1.135  -1.129  -1.114  -0.855  -0.852  -0.829
18    I        -0.957  -0.956  -0.945  -1.035  -1.015  -1.013  -0.855  -0.852  -0.829
19    E         0.381   0.398   0.364   0.077   0.100   0.047   0.247   0.274   0.216
20    D        -0.957  -0.956  -0.945  -0.898  -0.885  -0.875  -0.855  -0.852  -0.829
21    S        -0.957  -0.956  -0.945  -1.172  -1.170  -1.152  -0.855  -0.852  -0.829
22    I         0.381   0.357   0.346   0.368   0.332   0.319   0.247   0.208   0.186
23    A         0.381   0.393   0.360   0.607   0.624   0.581   0.247   0.267   0.210
24    V        -0.957  -0.956  -0.945  -0.415  -0.410  -0.388  -0.855  -0.852  -0.829
25    S         0.381   0.357   0.346   0.426   0.386   0.375   0.247   0.208   0.186
26    S         0.381   0.357   0.346   0.375   0.332   0.318   0.247   0.208   0.186
27    E         0.381   0.398   0.364   0.104   0.129   0.077   0.247   0.274   0.216
28    E        -0.957  -0.956  -0.945  -1.399  -1.386  -1.381  -0.855  -0.852  -0.829
29    V         0.381   0.357   0.346   0.514   0.468   0.441   0.247   0.208   0.186
30    L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
31    N        -0.957  -0.956  -0.945  -0.847  -0.844  -0.823  -0.855  -0.852  -0.829
32    N         0.381   0.393   0.360   0.100   0.121   0.067   0.247   0.267   0.210
33    Q         2.224   2.227   2.259   2.283   2.285   2.337   2.450   2.454   2.499
34    E         0.381   0.393   0.360   0.281   0.305   0.228   0.247   0.267   0.210
35    L        -0.957  -0.956  -0.945  -1.035  -1.017  -1.013  -0.855  -0.852  -0.829
36    R         0.381   0.357   0.346   0.451   0.403   0.361   0.247   0.208   0.186
37    L         0.381   0.357   0.346   0.148   0.123   0.108   0.247   0.208   0.186
38    K        -0.957  -0.956  -0.945  -0.717  -0.706  -0.692  -0.855  -0.852  -0.829
39    N        -0.957  -0.956  -0.945  -0.688  -0.691  -0.663  -0.855  -0.852  -0.829
40    T         2.224   2.227   2.259   2.380   2.382   2.435   2.450   2.454   2.499
41    L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
42    H         0.381   0.398   0.364   0.856   0.883   0.831   0.247   0.274   0.216
43    E         2.224   2.227   2.259   1.963   1.964   2.014   2.450   2.454   2.499
44    I         0.381   0.357   0.346   0.419   0.385   0.376   0.247   0.208   0.186
45    T        -0.957  -0.956  -0.945  -0.813  -0.805  -0.789  -0.855  -0.852  -0.829
46    S         0.381   0.393   0.360   0.352   0.369   0.312   0.247   0.267   0.210
47    S         0.381   0.357   0.346   0.375   0.332   0.318   0.247   0.208   0.186
48    I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
49    L         0.381   0.398   0.364   0.148   0.176   0.130   0.247   0.274   0.216
50    A        -0.957  -0.956  -0.945  -0.771  -0.772  -0.747  -0.855  -0.852  -0.829
51    I         0.381   0.393   0.360  -0.041  -0.016  -0.081   0.247   0.267   0.210
52    N        -0.957  -0.956  -0.945  -0.847  -0.835  -0.823  -0.855  -0.852  -0.829
53    E         0.381   0.357   0.346   0.053   0.010  -0.008   0.247   0.208   0.186
54    E        -0.957  -0.956  -0.945  -1.039  -1.034  -1.018  -0.855  -0.852  -0.829
55    N        -0.957  -0.956  -0.945  -0.742  -0.731  -0.717  -0.855  -0.852  -0.829
56    K        -0.957  -0.956  -0.945  -1.135  -1.141  -1.114  -0.855  -0.852  -0.829
57    F        -0.957  -0.956  -0.945  -0.328  -0.326  -0.300  -0.855  -0.852  -0.829
58    V        -0.957  -0.956  -0.945  -0.834  -0.819  -0.810  -0.855  -0.852  -0.829
59    N         0.381   0.398   0.364   0.397   0.434   0.363   0.247   0.274   0.216
60    P        -0.957  -0.956  -0.945  -0.942  -0.940  -0.919  -0.855  -0.852  -0.829
61    L        -0.957  -0.956  -0.945  -1.181  -1.167  -1.161  -0.855  -0.852  -0.829
62    R         0.381   0.393   0.360   0.856   0.876   0.824   0.247   0.267   0.210
63    N        -0.957  -0.956  -0.945  -0.872  -0.866  -0.849  -0.855  -0.852  -0.829
64    D         0.217   0.218   0.238   0.260   0.268   0.294  -0.029  -0.027   0.003
65    E         0.217   0.218   0.238  -0.199  -0.192  -0.169  -0.029  -0.027   0.003
66    S         2.224   2.227   2.259   2.322   2.325   2.377   2.450   2.454   2.499
67    L         2.224   2.227   2.259   1.915   1.916   1.965   2.450   2.454   2.499
68    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    V        -0.957  -0.956  -0.945  -0.591  -0.580  -0.565  -0.855  -0.852  -0.829
77    N         0.381   0.393   0.360   0.448   0.474   0.411   0.247   0.267   0.210
78    P         0.381   0.398   0.364   0.698   0.729   0.659   0.247   0.274   0.216
79    K         0.381   0.357   0.346   0.307   0.263   0.241   0.247   0.208   0.186
80    I        -0.957  -0.956  -0.945  -1.214  -1.223  -1.195  -0.855  -0.852  -0.829
81    L         0.381   0.357   0.346  -0.041  -0.076  -0.105   0.247   0.208   0.186
82    S        -0.957  -0.956  -0.945  -1.140  -1.129  -1.119  -0.855  -0.852  -0.829
83    A        -0.957  -0.956  -0.945  -0.842  -0.852  -0.819  -0.855  -0.852  -0.829
84    K         0.381   0.357   0.346   0.520   0.489   0.481   0.247   0.208   0.186
85    I        -0.957  -0.956  -0.945  -1.291  -1.297  -1.272  -0.855  -0.852  -0.829
86    K        -0.957  -0.956  -0.945  -0.995  -1.004  -0.973  -0.855  -0.852  -0.829
87    E         0.381   0.357   0.346   0.053   0.012  -0.008   0.247   0.208   0.186
88    F         0.381   0.393   0.360   0.178   0.198   0.159   0.247   0.267   0.210
89    N        -0.957  -0.956  -0.945  -1.071  -1.072  -1.050  -0.855  -0.852  -0.829
90    K         0.381   0.393   0.360   0.307   0.323   0.267   0.247   0.267   0.210
91    L         0.381   0.357   0.346   0.231   0.209   0.201   0.247   0.208   0.186
92    M         0.381   0.357   0.346   0.770   0.728   0.705   0.247   0.208   0.186
93    E        -0.957  -0.956  -0.945  -1.071  -1.059  -1.050  -0.855  -0.852  -0.829
94    L         0.381   0.357   0.346  -0.010  -0.045  -0.070   0.247   0.208   0.186
95    L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
96    K         0.381   0.398   0.364   0.454   0.479   0.434   0.247   0.274   0.216
97    L        -0.957  -0.956  -0.945  -1.214  -1.205  -1.195  -0.855  -0.852  -0.829
98    T        -0.957  -0.956  -0.945  -1.191  -1.185  -1.171  -0.855  -0.852  -0.829
99    Y         0.381   0.357   0.346   0.838   0.801   0.791   0.247   0.208   0.186
100   L         0.381   0.398   0.364   0.231   0.257   0.221   0.247   0.274   0.216
101   E         0.381   0.398   0.364   0.208   0.229   0.190   0.247   0.274   0.216
102   Q        -0.957  -0.956  -0.945  -1.399  -1.401  -1.381  -0.855  -0.852  -0.829
103   E         2.224   2.227   2.259   1.963   1.964   2.014   2.450   2.454   2.499
104   T         0.381   0.393   0.360   0.375   0.389   0.341   0.247   0.267   0.210
105   L         0.381   0.357   0.346  -0.041  -0.076  -0.105   0.247   0.208   0.186
106   D         2.224   2.227   2.259   2.339   2.345   2.393   2.450   2.454   2.499
107   Y        -0.957  -0.956  -0.945  -0.942  -0.929  -0.919  -0.855  -0.852  -0.829
108   F         2.224   2.227   2.259   2.610   2.612   2.667   2.450   2.454   2.499
109   F         0.381   0.393   0.360   0.178   0.198   0.159   0.247   0.267   0.210
110   R         0.381   0.398   0.364   0.598   0.629   0.562   0.247   0.274   0.216
111   F         0.381   0.393   0.360   0.806   0.822   0.778   0.247   0.267   0.210
112   T         0.381   0.357   0.346   0.607   0.571   0.560   0.247   0.208   0.186
113   L         0.381   0.393   0.360   0.090   0.115   0.035   0.247   0.267   0.210
114   S        -0.957  -0.956  -0.945  -0.684  -0.671  -0.659  -0.855  -0.852  -0.829
115   S         2.224   2.227   2.259   2.235   2.233   2.288   2.450   2.454   2.499
116   -         2.224   2.227   2.259   2.287   2.290   2.340   2.450   2.454   2.499
117   T        -0.957  -0.956  -0.945  -0.684  -0.689  -0.659  -0.855  -0.852  -0.829
118   K        -0.957  -0.956  -0.945  -1.107  -1.099  -1.086  -0.855  -0.852  -0.829
119   P        -0.957  -0.956  -0.945  -0.750  -0.757  -0.725  -0.855  -0.852  -0.829
120   L         0.381   0.398   0.364   0.117   0.145   0.098   0.247   0.274   0.216
121   Q        -0.957  -0.956  -0.945  -0.655  -0.655  -0.630  -0.855  -0.852  -0.829
122   L         0.381   0.398   0.364   0.117   0.145   0.098   0.247   0.274   0.216
123   D        -0.957  -0.956  -0.945  -0.729  -0.735  -0.705  -0.855  -0.852  -0.829
124   S         0.381   0.357   0.346   0.307   0.261   0.241   0.247   0.208   0.186
125   E        -0.957  -0.956  -0.945  -0.890  -0.877  -0.867  -0.855  -0.852  -0.829
126   K        -0.957  -0.956  -0.945  -0.877  -0.870  -0.853  -0.855  -0.852  -0.829
127   D         0.381   0.357   0.346   0.281   0.234   0.197   0.247   0.208   0.186
128   P         0.381   0.357   0.346   0.725   0.677   0.652   0.247   0.208   0.186
129   Q         0.381   0.393   0.360   0.329   0.348   0.292   0.247   0.267   0.210
130   F         0.381   0.393   0.360   0.806   0.822   0.778   0.247   0.267   0.210
131   V        -0.957  -0.956  -0.945  -1.003  -1.014  -0.982  -0.855  -0.852  -0.829
132   K        -0.957  -0.956  -0.945  -0.937  -0.935  -0.915  -0.855  -0.852  -0.829
133   L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
134   N         0.381   0.393   0.360   0.397   0.418   0.361   0.247   0.267   0.210
135   E        -0.957  -0.956  -0.945  -0.898  -0.885  -0.875  -0.855  -0.852  -0.829
136   R         0.381   0.393   0.360   0.208   0.223   0.185   0.247   0.267   0.210
137   V         2.224   2.227   2.259   2.489   2.492   2.545   2.450   2.454   2.499
138   N         0.381   0.393   0.360   0.352   0.371   0.316   0.247   0.267   0.210
139   D        -0.957  -0.956  -0.945  -0.842  -0.854  -0.819  -0.855  -0.852  -0.829
140   L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
141   K         0.381   0.393   0.360   0.598   0.620   0.555   0.247   0.267   0.210
142   E         0.381   0.393   0.360   0.281   0.305   0.228   0.247   0.267   0.210
143   E        -0.957  -0.956  -0.945  -1.177  -1.175  -1.157  -0.855  -0.852  -0.829
144   I        -0.957  -0.956  -0.945  -0.847  -0.841  -0.823  -0.855  -0.852  -0.829
145   S        -0.957  -0.956  -0.945  -0.603  -0.604  -0.577  -0.855  -0.852  -0.829
146   N        -0.957  -0.956  -0.945  -0.721  -0.712  -0.696  -0.855  -0.852  -0.829
147   V         0.381   0.357   0.346   0.564   0.519   0.497   0.247   0.208   0.186
148   Q        -0.957  -0.956  -0.945  -1.214  -1.219  -1.195  -0.855  -0.852  -0.829
149   E        -0.957  -0.956  -0.945  -1.107  -1.100  -1.086  -0.855  -0.852  -0.829
150   S        -0.957  -0.956  -0.945  -0.999  -1.002  -0.977  -0.855  -0.852  -0.829
151   K         0.381   0.393   0.360   0.053   0.070   0.015   0.247   0.267   0.210
152   I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
153   E         0.381   0.398   0.364   0.104   0.129   0.077   0.247   0.274   0.216
154   Q         0.381   0.357   0.346   0.352   0.306   0.286   0.247   0.208   0.186
155   I         0.381   0.357   0.346   0.090   0.044   0.005   0.247   0.208   0.186
156   K        -0.957  -0.956  -0.945  -0.907  -0.908  -0.884  -0.855  -0.852  -0.829
157   A        -0.957  -0.956  -0.945  -0.504  -0.511  -0.477  -0.855  -0.852  -0.829
158   E         0.381   0.357   0.346   0.077   0.036   0.019   0.247   0.208   0.186
159   I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
160   Q        -0.957  -0.956  -0.945  -1.117  -1.105  -1.096  -0.855  -0.852  -0.829
161   E        -0.957  -0.956  -0.945  -1.075  -1.071  -1.054  -0.855  -0.852  -0.829
162   T        -0.957  -0.956  -0.945  -0.779  -0.783  -0.755  -0.855  -0.852  -0.829
163   G        -0.957  -0.956  -0.945  -0.532  -0.541  -0.505  -0.855  -0.852  -0.829
164   H         0.381   0.357   0.346   0.764   0.722   0.697   0.247   0.208   0.186
165   N         0.381   0.393   0.360   0.100   0.121   0.067   0.247   0.267   0.210
166   F        -0.957  -0.956  -0.945  -0.771  -0.765  -0.747  -0.855  -0.852  -0.829
167   A        -0.957  -0.956  -0.945  -0.911  -0.920  -0.888  -0.855  -0.852  -0.829
168   E         0.381   0.357   0.346  -0.112  -0.157  -0.194   0.247   0.208   0.186
169   R        -0.957  -0.956  -0.945  -0.868  -0.870  -0.845  -0.855  -0.852  -0.829
170   Q         0.381   0.357   0.346   0.352   0.306   0.286   0.247   0.208   0.186
171   D         0.381   0.357   0.346   0.281   0.234   0.197   0.247   0.208   0.186
172   L        -0.957  -0.956  -0.945  -1.214  -1.207  -1.195  -0.855  -0.852  -0.829
173   I         0.381   0.398   0.364   0.368   0.392   0.346   0.247   0.274   0.216
174   N         0.381   0.357   0.346   0.397   0.362   0.330   0.247   0.208   0.186
175   E         0.381   0.398   0.364   0.267   0.287   0.254   0.247   0.274   0.216
176   L         0.381   0.357   0.346  -0.010  -0.045  -0.070   0.247   0.208   0.186
177   Y         0.381   0.357   0.346   0.867   0.832   0.824   0.247   0.208   0.186
178   L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
179   E         2.224   2.227   2.259   1.963   1.964   2.014   2.450   2.454   2.499
180   A         0.381   0.398   0.364   0.704   0.733   0.674   0.247   0.274   0.216
181   T         0.381   0.357   0.346   0.442   0.396   0.374   0.247   0.208   0.186
182   G        -0.957  -0.956  -0.945  -0.660  -0.659  -0.634  -0.855  -0.852  -0.829
183   D         0.381   0.398   0.364   0.281   0.315   0.236   0.247   0.274   0.216
184   I         0.381   0.398   0.364   0.090   0.124   0.044   0.247   0.274   0.216
185   E         0.381   0.393   0.360   0.281   0.305   0.228   0.247   0.267   0.210
186   N        -0.957  -0.956  -0.945  -0.937  -0.931  -0.915  -0.855  -0.852  -0.829
187   C         2.224   2.227   2.259   2.748   2.751   2.806   2.450   2.454   2.499
188   W         2.224   2.227   2.259   2.715   2.719   2.773   2.450   2.454   2.499
189   D        -0.957  -0.956  -0.945  -1.135  -1.129  -1.114  -0.855  -0.852  -0.829
190   S         0.381   0.393   0.360  -0.010   0.013  -0.047   0.247   0.267   0.210
191   L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
192   N        -0.957  -0.956  -0.945  -1.071  -1.072  -1.050  -0.855  -0.852  -0.829
193   E         0.381   0.357   0.346   0.077   0.036   0.019   0.247   0.208   0.186
194   L         0.381   0.398   0.364   0.231   0.257   0.221   0.247   0.274   0.216
195   K        -0.957  -0.956  -0.945  -1.172  -1.180  -1.152  -0.855  -0.852  -0.829
196   N        -0.957  -0.956  -0.945  -0.555  -0.545  -0.529  -0.855  -0.852  -0.829
197   L         0.381   0.357   0.346   0.171   0.146   0.134   0.247   0.208   0.186
198   T        -0.957  -0.956  -0.945  -1.075  -1.086  -1.054  -0.855  -0.852  -0.829
199   N         0.217   0.218   0.238   0.036   0.051   0.068  -0.029  -0.027   0.003
200   K         0.217   0.218   0.238  -0.038  -0.031  -0.007  -0.029  -0.027   0.003
201   E         0.217   0.218   0.238  -0.099  -0.099  -0.068  -0.029  -0.027   0.003
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   D         0.381   0.393   0.360   0.445   0.473   0.408   0.247   0.267   0.210
207   K        -0.957  -0.956  -0.945  -0.964  -0.949  -0.941  -0.855  -0.852  -0.829
208   N         0.381   0.398   0.364   0.445   0.481   0.415   0.247   0.274   0.216
209   M        -0.957  -0.956  -0.945  -0.431  -0.419  -0.403  -0.855  -0.852  -0.829
210   M         0.381   0.393   0.360   0.511   0.524   0.490   0.247   0.267   0.210
211   G        -0.957  -0.956  -0.945  -0.603  -0.599  -0.577  -0.855  -0.852  -0.829
212   E         0.381   0.398   0.364   0.208   0.229   0.190   0.247   0.274   0.216
213   K         0.381   0.357   0.346   0.426   0.390   0.375   0.247   0.208   0.186
214   D         0.381   0.357   0.346   0.375   0.333   0.304   0.247   0.208   0.186
215   T         2.224   2.227   2.259   2.380   2.382   2.435   2.450   2.454   2.499
216   I        -0.957  -0.956  -0.945  -1.149  -1.141  -1.128  -0.855  -0.852  -0.829
217   L         0.381   0.357   0.346   0.063   0.033   0.012   0.247   0.208   0.186
218   N         0.381   0.357   0.346   0.445   0.413   0.384   0.247   0.208   0.186
219   S        -0.957  -0.956  -0.945  -0.528  -0.523  -0.501  -0.855  -0.852  -0.829
220   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   V        -0.957  -0.956  -0.945  -0.396  -0.394  -0.369  -0.855  -0.852  -0.829
227   E         0.381   0.357   0.346   0.238   0.206   0.200   0.247   0.208   0.186
228   E         0.381   0.357   0.346   0.053   0.010  -0.008   0.247   0.208   0.186
229   T         0.381   0.398   0.364   0.677   0.699   0.663   0.247   0.274   0.216
230   Y         2.224   2.227   2.259   2.596   2.598   2.653   2.450   2.454   2.499
231   T        -0.957  -0.956  -0.945  -1.044  -1.033  -1.022  -0.855  -0.852  -0.829
232   N        -0.957  -0.956  -0.945  -1.107  -1.098  -1.086  -0.855  -0.852  -0.829
233   W         2.224   2.227   2.259   2.715   2.719   2.773   2.450   2.454   2.499
234   Q         0.381   0.393   0.360   0.329   0.348   0.292   0.247   0.267   0.210
235   K        -0.957  -0.956  -0.945  -0.639  -0.629  -0.614  -0.855  -0.852  -0.829
236   L         0.381   0.357   0.346   0.039   0.013  -0.015   0.247   0.208   0.186
237   L        -0.957  -0.956  -0.945  -1.399  -1.387  -1.381  -0.855  -0.852  -0.829
238   F        -0.957  -0.956  -0.945  -1.167  -1.172  -1.147  -0.855  -0.852  -0.829
239   L         0.381   0.357   0.346   0.171   0.147   0.134   0.247   0.208   0.186
240   Q        -0.957  -0.956  -0.945  -0.933  -0.945  -0.910  -0.855  -0.852  -0.829
241   K        -0.957  -0.956  -0.945  -0.868  -0.873  -0.845  -0.855  -0.852  -0.829
242   Q        -0.957  -0.956  -0.945  -1.399  -1.399  -1.381  -0.855  -0.852  -0.829
243   N         0.381   0.357   0.346   0.244   0.205   0.157   0.247   0.208   0.186
244   Q        -0.957  -0.956  -0.945  -0.933  -0.932  -0.910  -0.855  -0.852  -0.829
245   R        -0.957  -0.956  -0.945  -0.504  -0.491  -0.477  -0.855  -0.852  -0.829
246   L         0.381   0.357   0.346  -0.041  -0.076  -0.105   0.247   0.208   0.186
247   T        -0.957  -0.956  -0.945  -0.847  -0.841  -0.823  -0.855  -0.852  -0.829
248   K         0.381   0.357   0.346   0.329   0.288   0.267   0.247   0.208   0.186
249   E         0.381   0.393   0.360   0.228   0.248   0.175   0.247   0.267   0.210
250   L         0.381   0.398   0.364  -0.041  -0.009  -0.075   0.247   0.274   0.216
251   K        -0.957  -0.956  -0.945  -1.003  -1.003  -0.982  -0.855  -0.852  -0.829
252   E         0.381   0.357   0.346   0.124   0.086   0.072   0.247   0.208   0.186
253   M         0.381   0.393   0.360   0.208   0.229   0.191   0.247   0.267   0.210
254   H        -0.957  -0.956  -0.945  -0.713  -0.705  -0.688  -0.855  -0.852  -0.829
255   E        -0.957  -0.956  -0.945  -0.964  -0.951  -0.941  -0.855  -0.852  -0.829
256   V         0.381   0.357   0.346   0.607   0.565   0.545   0.247   0.208   0.186
257   K         0.381   0.398   0.364   0.355   0.384   0.326   0.247   0.274   0.216
258   N         0.381   0.357   0.346   0.274   0.232   0.191   0.247   0.208   0.186
259   Q         0.381   0.393   0.360   0.329   0.348   0.292   0.247   0.267   0.210
260   I        -0.957  -0.956  -0.945  -1.044  -1.051  -1.022  -0.855  -0.852  -0.829
261   I         0.381   0.357   0.346   0.297   0.259   0.239   0.247   0.208   0.186
262   R        -0.957  -0.956  -0.945  -0.771  -0.767  -0.747  -0.855  -0.852  -0.829
263   K        -0.957  -0.956  -0.945  -0.868  -0.863  -0.845  -0.855  -0.852  -0.829
264   G        -0.957  -0.956  -0.945  -0.442  -0.439  -0.415  -0.855  -0.852  -0.829
265   E        -0.957  -0.956  -0.945  -1.172  -1.174  -1.152  -0.855  -0.852  -0.829
266   Q        -0.957  -0.956  -0.945  -1.214  -1.205  -1.195  -0.855  -0.852  -0.829
267   S        -0.957  -0.956  -0.945  -0.611  -0.608  -0.585  -0.855  -0.852  -0.829
268   K        -0.957  -0.956  -0.945  -1.205  -1.203  -1.185  -0.855  -0.852  -0.829
269   K         0.381   0.393   0.360   0.053   0.070   0.015   0.247   0.267   0.210
270   E        -0.957  -0.956  -0.945  -1.434  -1.439  -1.417  -0.855  -0.852  -0.829
271   D         0.217   0.218   0.238  -0.065  -0.065  -0.034  -0.029  -0.027   0.003
272   S         0.217   0.218   0.238   0.055   0.056   0.088  -0.029  -0.027   0.003
273   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   M        -0.957  -0.956  -0.945  -0.792  -0.796  -0.768  -0.855  -0.852  -0.829
277   A        -0.957  -0.956  -0.945  -0.385  -0.380  -0.357  -0.855  -0.852  -0.829
278   N         0.381   0.357   0.346   0.397   0.362   0.330   0.247   0.208   0.186
279   E        -0.957  -0.956  -0.945  -1.107  -1.110  -1.086  -0.855  -0.852  -0.829
280   S        -0.957  -0.956  -0.945  -0.907  -0.914  -0.884  -0.855  -0.852  -0.829
281   E         0.381   0.398   0.364   0.077   0.100   0.047   0.247   0.274   0.216
282   L         0.381   0.357   0.346   0.063   0.033   0.012   0.247   0.208   0.186
283   C         0.217   0.218   0.238   0.597   0.598   0.634  -0.029  -0.027   0.003
284   Q         0.217   0.218   0.238   0.166   0.166   0.199  -0.029  -0.027   0.003
285   S         2.224   2.227   2.259   2.174   2.177   2.227   2.450   2.454   2.499
286   I         0.217   0.218   0.238   0.245   0.246   0.279  -0.029  -0.027   0.003
287   N         0.381   0.357   0.346   0.419   0.385   0.355   0.247   0.208   0.186
288   L         0.381   0.398   0.364   0.042   0.074   0.016   0.247   0.274   0.216
289   L         2.224   2.227   2.259   1.897   1.906   1.947   2.450   2.454   2.499
290   T        -0.957  -0.956  -0.945  -0.977  -0.980  -0.955  -0.855  -0.852  -0.829
291   K        -0.957  -0.956  -0.945  -0.933  -0.931  -0.910  -0.855  -0.852  -0.829
292   F        -0.957  -0.956  -0.945  -0.721  -0.732  -0.696  -0.855  -0.852  -0.829
293   W         2.224   2.227   2.259   2.715   2.719   2.773   2.450   2.454   2.499
294   E        -0.957  -0.956  -0.945  -0.995  -0.982  -0.973  -0.855  -0.852  -0.829
295   K        -0.957  -0.956  -0.945  -0.830  -0.834  -0.806  -0.855  -0.852  -0.829
296   H        -0.957  -0.956  -0.945  -0.559  -0.565  -0.533  -0.855  -0.852  -0.829
297   F         0.381   0.398   0.364   0.625   0.655   0.587   0.247   0.274   0.216
298   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   L         0.381   0.393   0.360   0.090   0.115   0.035   0.247   0.267   0.210
300   K        -0.957  -0.956  -0.945  -0.611  -0.606  -0.585  -0.855  -0.852  -0.829
301   G        -0.957  -0.956  -0.945  -0.717  -0.722  -0.692  -0.855  -0.852  -0.829
302   S        -0.957  -0.956  -0.945  -1.291  -1.296  -1.272  -0.855  -0.852  -0.829
303   K        -0.957  -0.956  -0.945  -0.946  -0.955  -0.924  -0.855  -0.852  -0.829
304   T        -0.957  -0.956  -0.945  -0.813  -0.800  -0.789  -0.855  -0.852  -0.829
305   T         0.381   0.393   0.360   0.470   0.491   0.435   0.247   0.267   0.210
306   I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
307   L        -0.957  -0.956  -0.945  -1.003  -0.988  -0.982  -0.855  -0.852  -0.829
308   N         0.381   0.398   0.364   0.274   0.313   0.229   0.247   0.274   0.216
309   F        -0.957  -0.956  -0.945  -1.035  -1.041  -1.013  -0.855  -0.852  -0.829
310   E         0.381   0.398   0.364   0.178   0.199   0.158   0.247   0.274   0.216
311   I        -0.957  -0.956  -0.945  -1.117  -1.100  -1.096  -0.855  -0.852  -0.829
312   F         0.381   0.393   0.360   0.806   0.822   0.778   0.247   0.267   0.210
313   T         0.381   0.393   0.360   0.788   0.808   0.750   0.247   0.267   0.210
314   Q         0.381   0.398   0.364   0.520   0.542   0.501   0.247   0.274   0.216
315   L         0.381   0.393   0.360   0.151   0.173   0.096   0.247   0.267   0.210
316   G         0.381   0.398   0.364   0.856   0.883   0.831   0.247   0.274   0.216
317   K         2.224   2.227   2.259   2.235   2.238   2.288   2.450   2.454   2.499
318   V         0.381   0.393   0.360   0.117   0.139   0.092   0.247   0.267   0.210
319   Q         0.381   0.357   0.346   0.352   0.308   0.286   0.247   0.208   0.186
320   F         0.381   0.398   0.364   0.508   0.544   0.459   0.247   0.274   0.216
321   E         0.381   0.398   0.364   0.208   0.229   0.190   0.247   0.274   0.216
322   I         0.381   0.393   0.360   0.514   0.535   0.469   0.247   0.267   0.210
323   K        -0.957  -0.956  -0.945  -0.532  -0.524  -0.505  -0.855  -0.852  -0.829
324   D        -0.957  -0.956  -0.945  -0.942  -0.937  -0.919  -0.855  -0.852  -0.829
325   M         2.224   2.227   2.259   2.676   2.680   2.734   2.450   2.454   2.499
326   Q         0.381   0.398   0.364   0.498   0.522   0.477   0.247   0.274   0.216
327   Y         0.381   0.357   0.346   0.752   0.711   0.695   0.247   0.208   0.186
328   I         0.381   0.398   0.364   0.317   0.341   0.290   0.247   0.274   0.216
329   I         0.381   0.357   0.346   0.454   0.423   0.415   0.247   0.208   0.186
330   A        -0.957  -0.956  -0.945  -0.809  -0.810  -0.785  -0.855  -0.852  -0.829
331   I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
332   S        -0.957  -0.956  -0.945  -1.172  -1.183  -1.152  -0.855  -0.852  -0.829
333   L         2.224   2.227   2.259   1.915   1.916   1.965   2.450   2.454   2.499
334   S         0.217   0.218   0.238   0.059   0.066   0.091  -0.029  -0.027   0.003
335   D         0.217   0.218   0.238  -0.038  -0.031  -0.007  -0.029  -0.027   0.003
336   L         0.217   0.218   0.238   0.117   0.117   0.150  -0.029  -0.027   0.003
337   K         0.217   0.218   0.238   0.059   0.058   0.091  -0.029  -0.027   0.003
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   R        -0.957  -0.956  -0.945  -0.830  -0.833  -0.806  -0.855  -0.852  -0.829
343   P        -0.957  -0.956  -0.945  -0.477  -0.472  -0.450  -0.855  -0.852  -0.829
344   M        -0.957  -0.956  -0.945  -0.704  -0.711  -0.680  -0.855  -0.852  -0.829
345   I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
346   K         0.381   0.398   0.364   0.517   0.540   0.502   0.247   0.274   0.216
347   D         0.381   0.357   0.346   0.403   0.361   0.336   0.247   0.208   0.186
348   I         0.381   0.357   0.346   0.368   0.332   0.319   0.247   0.208   0.186
349   T        -0.957  -0.956  -0.945  -0.872  -0.875  -0.849  -0.855  -0.852  -0.829
350   I         0.381   0.393   0.360  -0.041  -0.016  -0.081   0.247   0.267   0.210
351   L         0.381   0.393   0.360   0.508   0.534   0.450   0.247   0.267   0.210
352   Q        -0.957  -0.956  -0.945  -0.907  -0.912  -0.884  -0.855  -0.852  -0.829
353   K        -0.957  -0.956  -0.945  -0.964  -0.951  -0.941  -0.855  -0.852  -0.829
354   A        -0.957  -0.956  -0.945  -0.933  -0.944  -0.910  -0.855  -0.852  -0.829
355   G        -0.957  -0.956  -0.945  -0.881  -0.887  -0.858  -0.855  -0.852  -0.829
356   G         0.381   0.393   0.360   0.517   0.529   0.497   0.247   0.267   0.210
357   N         0.217   0.218   0.238   0.267   0.275   0.301  -0.029  -0.027   0.003
358   I         0.381   0.357   0.346   0.419   0.385   0.376   0.247   0.208   0.186
359   V        -0.957  -0.956  -0.945  -0.842  -0.839  -0.819  -0.855  -0.852  -0.829
360   T        -0.957  -0.956  -0.945  -0.473  -0.472  -0.446  -0.855  -0.852  -0.829
361   D        -0.957  -0.956  -0.945  -0.729  -0.734  -0.705  -0.855  -0.852  -0.829
362   I        -0.957  -0.956  -0.945  -1.035  -1.044  -1.013  -0.855  -0.852  -0.829
363   E         0.381   0.357   0.346   0.124   0.086   0.072   0.247   0.208   0.186
364   A        -0.957  -0.956  -0.945  -1.044  -1.039  -1.022  -0.855  -0.852  -0.829
365   S        -0.957  -0.956  -0.945  -0.830  -0.834  -0.806  -0.855  -0.852  -0.829
366   S        -0.957  -0.956  -0.945  -1.205  -1.214  -1.185  -0.855  -0.852  -0.829
367   K        -0.957  -0.956  -0.945  -0.933  -0.929  -0.910  -0.855  -0.852  -0.829
368   F        -0.957  -0.956  -0.945  -0.676  -0.684  -0.651  -0.855  -0.852  -0.829
369   N         0.381   0.393   0.360   0.039   0.066   0.006   0.247   0.267   0.210
370   N        -0.957  -0.956  -0.945  -0.660  -0.645  -0.634  -0.855  -0.852  -0.829
371   K        -0.957  -0.956  -0.945  -0.995  -0.981  -0.973  -0.855  -0.852  -0.829
372   Y        -0.957  -0.956  -0.945  -0.528  -0.539  -0.501  -0.855  -0.852  -0.829
373   R        -0.957  -0.956  -0.945  -0.995  -1.003  -0.973  -0.855  -0.852  -0.829
374   N        -0.957  -0.956  -0.945  -0.427  -0.417  -0.399  -0.855  -0.852  -0.829
375   N        -0.957  -0.956  -0.945  -0.660  -0.660  -0.634  -0.855  -0.852  -0.829
376   T        -0.957  -0.956  -0.945  -0.937  -0.940  -0.915  -0.855  -0.852  -0.829
377   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   Q        -0.957  -0.956  -0.945  -0.937  -0.936  -0.915  -0.855  -0.852  -0.829
380   I         0.381   0.357   0.346   0.090   0.044   0.005   0.247   0.208   0.186
381   F         0.381   0.398   0.364   0.508   0.544   0.459   0.247   0.274   0.216
382   E        -0.957  -0.956  -0.945  -1.172  -1.170  -1.152  -0.855  -0.852  -0.829
383   V         0.381   0.398   0.364   0.704   0.729   0.683   0.247   0.274   0.216
384   M         0.381   0.393   0.360   0.208   0.229   0.191   0.247   0.267   0.210
385   D        -0.957  -0.956  -0.945  -0.804  -0.796  -0.780  -0.855  -0.852  -0.829
386   D        -0.957  -0.956  -0.945  -0.746  -0.734  -0.721  -0.855  -0.852  -0.829
387   I         2.224   2.227   2.259   2.171   2.174   2.224   2.450   2.454   2.499
388   I         0.381   0.357   0.346   0.317   0.277   0.261   0.247   0.208   0.186
389   S        -0.957  -0.956  -0.945  -0.903  -0.895  -0.880  -0.855  -0.852  -0.829
390   E        -0.957  -0.956  -0.945  -0.767  -0.759  -0.742  -0.855  -0.852  -0.829
391   L        -0.957  -0.956  -0.945  -1.117  -1.114  -1.096  -0.855  -0.852  -0.829
392   T        -0.957  -0.956  -0.945  -0.817  -0.811  -0.793  -0.855  -0.852  -0.829
393   N         2.224   2.227   2.259   2.332   2.344   2.386   2.450   2.454   2.499
394   E        -0.957  -0.956  -0.945  -1.140  -1.135  -1.119  -0.855  -0.852  -0.829
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -         0.217   0.218   0.238  -0.110  -0.108  -0.079  -0.029  -0.027   0.003
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04431
Output conservation file - output/Q04431
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
