1     M         1.681   1.744   1.849   1.922   2.013   2.185   1.873   1.971   2.161
2     S         0.958   0.850   0.767   0.859   0.716   0.593   1.018   0.831   0.646
3     T        -0.187  -0.050  -0.140  -0.522  -0.349  -0.410  -0.448  -0.299  -0.355
4     A        -1.642  -1.539  -1.497  -1.652  -1.439  -1.431  -1.303  -1.191  -1.096
5     R        -1.642  -1.604  -1.529  -1.618  -1.612  -1.462  -1.303  -1.239  -1.119
6     P        -1.184  -1.170  -1.146  -0.939  -0.913  -0.874  -1.058  -1.024  -0.953
7     R         0.270   0.096  -0.006   0.464   0.242   0.081   0.285   0.033  -0.135
8     I        -0.313  -0.037  -0.131  -0.652  -0.202  -0.383  -0.570  -0.164  -0.325
9     I        -1.642  -1.555  -1.512  -1.510  -1.377  -1.328  -1.303  -1.208  -1.106
10    T        -0.852  -0.813  -0.723  -0.859  -0.782  -0.644  -0.936  -0.873  -0.747
11    S        -1.310  -1.302  -1.165  -1.584  -1.524  -1.335  -1.180  -1.132  -0.970
12    K         0.352   0.414   0.536   0.055   0.155   0.341  -0.081   0.009   0.186
13    A        -0.977  -1.071  -1.122  -0.794  -0.957  -1.009  -0.814  -0.906  -0.926
14    P        -0.045  -0.006  -0.101   0.003   0.066  -0.137  -0.203  -0.142  -0.293
15    L        -1.184  -1.044  -1.118  -1.321  -1.058  -1.230  -1.058  -0.884  -0.924
16    L         0.270   0.152  -0.023   0.228   0.062  -0.226   0.285   0.111  -0.161
17    P         0.270   0.152  -0.023   0.512   0.343   0.044   0.285   0.111  -0.161
18    Q        -0.645  -0.457  -0.629  -0.724  -0.439  -0.670  -0.692  -0.436  -0.630
19    Q        -0.645  -0.727  -0.706  -0.477  -0.603  -0.585  -0.692  -0.785  -0.729
20    T        -0.378  -0.563  -0.660  -0.283  -0.563  -0.772  -0.326  -0.553  -0.666
21    T         1.681   1.744   1.849   1.643   1.740   1.909   1.873   1.971   2.161
22    P         0.412   0.435   0.537   0.263   0.267   0.406   0.041   0.052   0.188
23    E         1.681   1.744   1.849   1.761   1.859   2.026   1.873   1.971   2.161
24    Q         0.958   0.903   0.783   1.174   1.132   0.949   1.018   0.921   0.677
25    R         0.603   0.585   0.590   0.540   0.499   0.460   0.407   0.349   0.297
26    Y         0.603   0.585   0.590   0.741   0.707   0.678   0.407   0.349   0.297
27    W         1.681   1.744   1.849   1.942   2.038   2.205   1.873   1.971   2.161
28    R         0.603   0.557   0.577   0.540   0.448   0.432   0.407   0.295   0.270
29    Q        -0.645  -0.425  -0.596  -0.750  -0.423  -0.661  -0.692  -0.389  -0.589
30    Y         0.412   0.427   0.537   0.407   0.413   0.569   0.041   0.036   0.187
31    T        -1.642  -1.474  -1.499  -1.711  -1.420  -1.477  -1.303  -1.133  -1.097
32    S        -1.184  -1.166  -1.128  -1.297  -1.265  -1.194  -1.058  -1.025  -0.938
33    A        -0.645  -0.493  -0.647  -0.528  -0.260  -0.525  -0.692  -0.486  -0.653
34    Q        -0.378  -0.563  -0.660  -0.148  -0.432  -0.677  -0.326  -0.553  -0.666
35    L         0.270   0.074  -0.044   0.203  -0.090  -0.320   0.285   0.001  -0.192
36    V        -0.378  -0.610  -0.639  -0.285  -0.597  -0.640  -0.326  -0.609  -0.641
37    K         0.958   0.850   0.767   1.009   0.877   0.738   1.018   0.831   0.646
38    E         0.958   0.850   0.767   1.099   0.955   0.797   1.018   0.831   0.646
39    H        -0.852  -0.884  -0.748  -0.689  -0.730  -0.543  -0.936  -0.942  -0.772
40    N        -0.977  -1.110  -1.121  -0.655  -0.883  -0.899  -0.814  -0.946  -0.925
41    S        -0.313  -0.142  -0.116  -0.544  -0.254  -0.237  -0.570  -0.327  -0.301
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    V         0.412   0.614   0.634   0.169   0.545   0.537   0.041   0.405   0.387
45    T         0.603   0.557   0.577   0.433   0.325   0.295   0.407   0.295   0.270
46    H         0.412   0.441   0.552   0.260   0.271   0.425   0.041   0.064   0.218
47    I         0.603   0.726   0.627   0.546   0.742   0.521   0.407   0.611   0.372
48    S        -1.184  -1.122  -1.095  -1.234  -1.107  -1.051  -1.058  -0.960  -0.901
49    F         1.681   1.744   1.849   1.814   1.914   2.078   1.873   1.971   2.161
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    N         0.270   0.074  -0.044   0.487   0.205  -0.038   0.285   0.001  -0.192
66    P         0.534   0.463   0.550   0.495   0.324   0.435   0.278   0.108   0.214
67    Q        -1.148  -1.249  -1.177  -0.986  -1.155  -1.103  -0.998  -1.086  -0.979
68    H        -0.852  -0.748  -0.734  -0.932  -0.836  -0.800  -0.936  -0.830  -0.761
69    P         0.270   0.152  -0.023   0.580   0.439   0.187   0.285   0.111  -0.161
70    H        -0.727  -0.791  -0.713  -0.535  -0.590  -0.482  -0.814  -0.841  -0.733
71    D         0.958   0.850   0.767   1.055   0.910   0.758   1.018   0.831   0.646
72    F         1.681   1.744   1.849   1.814   1.914   2.078   1.873   1.971   2.161
73    A         1.681   1.744   1.849   1.639   1.725   1.905   1.873   1.971   2.161
74    V         0.958   0.929   0.799   0.923   0.901   0.727   1.018   0.964   0.707
75    T         0.958   0.929   0.799   1.000   0.975   0.783   1.018   0.964   0.707
76    S         1.681   1.744   1.849   1.503   1.592   1.771   1.873   1.971   2.161
77    S        -0.045  -0.164  -0.140  -0.244  -0.448  -0.391  -0.203  -0.388  -0.349
78    T         0.270   0.074  -0.044   0.390   0.132  -0.062   0.285   0.001  -0.192
79    R         0.958   0.929   0.799   1.063   1.040   0.845   1.018   0.964   0.707
80    V         0.412   0.461   0.562   0.101   0.172   0.329   0.041   0.105   0.240
81    Q         0.958   0.850   0.767   1.164   1.043   0.898   1.018   0.831   0.646
82    I         0.352   0.427   0.554   0.011   0.147   0.353  -0.081   0.036   0.222
83    F         0.958   0.903   0.783   1.202   1.155   0.988   1.018   0.921   0.677
84    S         0.958   0.903   0.783   0.867   0.801   0.637   1.018   0.921   0.677
85    S        -0.378  -0.563  -0.660  -0.372  -0.646  -0.787  -0.326  -0.553  -0.666
86    R        -0.187  -0.211  -0.149  -0.373  -0.406  -0.323  -0.448  -0.459  -0.366
87    T         0.270   0.074  -0.044   0.343   0.063  -0.167   0.285   0.001  -0.192
88    R         1.681   1.744   1.849   1.704   1.801   1.970   1.873   1.971   2.161
89    Q        -0.378  -0.563  -0.660  -0.111  -0.383  -0.602  -0.326  -0.553  -0.666
90    V         0.270   0.304   0.013   0.251   0.277  -0.150   0.285   0.311  -0.107
91    I        -0.378  -0.563  -0.660  -0.183  -0.483  -0.687  -0.326  -0.553  -0.666
92    K         1.681   1.744   1.849   1.651   1.750   1.918   1.873   1.971   2.161
93    T         1.681   1.744   1.849   1.643   1.740   1.909   1.873   1.971   2.161
94    F         0.412   0.418   0.537   0.331   0.308   0.485   0.041   0.016   0.187
95    S         0.270   0.074  -0.044   0.231  -0.046  -0.231   0.285   0.001  -0.192
96    R         1.681   1.744   1.849   1.704   1.801   1.970   1.873   1.971   2.161
97    F         1.681   1.744   1.849   1.814   1.914   2.078   1.873   1.971   2.161
98    K         0.958   0.850   0.767   1.019   0.891   0.761   1.018   0.831   0.646
99    D         0.958   0.850   0.767   1.052   0.905   0.752   1.018   0.831   0.646
100   V        -0.187  -0.245  -0.148  -0.445  -0.487  -0.330  -0.448  -0.499  -0.365
101   V         0.603   0.520   0.573   0.387   0.222   0.287   0.407   0.221   0.263
102   Y         0.603   0.624   0.587   0.759   0.793   0.702   0.407   0.423   0.291
103   S         0.958   0.993   0.788   0.907   0.966   0.736   1.018   1.068   0.687
104   A         0.412   0.614   0.634   0.167   0.517   0.529   0.041   0.405   0.387
105   S        -1.310  -1.125  -1.147  -1.315  -0.996  -1.026  -1.180  -0.994  -0.955
106   F        -0.394  -0.363  -0.231  -0.399  -0.361  -0.163  -0.692  -0.644  -0.471
107   R         1.681   1.744   1.849   1.704   1.801   1.970   1.873   1.971   2.161
108   S        -1.310  -1.247  -1.157  -1.338  -1.247  -1.111  -1.180  -1.099  -0.964
109   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
110   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
111   K         0.958   0.850   0.767   1.018   0.890   0.758   1.018   0.831   0.646
112   L         0.958   0.850   0.767   0.865   0.724   0.581   1.018   0.831   0.646
113   L         0.958   0.993   0.788   0.893   0.954   0.682   1.018   1.068   0.687
114   C        -0.045   0.062  -0.040  -0.112   0.042  -0.104  -0.203  -0.019  -0.189
115   A         1.681   1.744   1.849   1.639   1.725   1.905   1.873   1.971   2.161
116   G         0.270   0.318   0.029   0.387   0.439   0.005   0.285   0.349  -0.081
117   D         0.958   0.850   0.767   1.089   0.960   0.836   1.018   0.831   0.646
118   A         0.958   0.850   0.767   1.007   0.867   0.749   1.018   0.831   0.646
119   T         0.412   0.431   0.545   0.053   0.046   0.217   0.041   0.044   0.204
120   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
121   L         0.958   0.850   0.767   0.880   0.746   0.615   1.018   0.831   0.646
122   V         0.958   0.850   0.767   0.950   0.835   0.738   1.018   0.831   0.646
123   S        -0.187  -0.090  -0.142  -0.419  -0.249  -0.287  -0.448  -0.336  -0.357
124   V         0.352   0.423   0.539   0.011   0.135   0.310  -0.081   0.027   0.191
125   Y         0.352   0.434   0.558   0.283   0.420   0.604  -0.081   0.051   0.231
126   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   S         0.154  -0.033  -0.106   0.070  -0.222  -0.349   0.118  -0.164  -0.286
130   Y        -0.378  -0.563  -0.660  -0.078  -0.376  -0.608  -0.326  -0.553  -0.666
131   N        -0.852  -0.884  -0.748  -0.921  -0.990  -0.808  -0.936  -0.942  -0.772
132   P         0.154  -0.052  -0.106   0.357   0.048  -0.082   0.118  -0.186  -0.286
133   R         0.958   0.850   0.767   1.062   0.925   0.787   1.018   0.831   0.646
134   T        -0.852  -0.886  -0.744  -1.064  -1.111  -0.915  -0.936  -0.944  -0.770
135   I         0.352   0.427   0.554  -0.011   0.129   0.335  -0.081   0.036   0.222
136   L         1.681   1.744   1.849   1.521   1.617   1.789   1.873   1.971   2.161
137   L        -0.645  -0.680  -0.663  -0.831  -0.834  -0.846  -0.692  -0.696  -0.672
138   S        -0.045  -0.158  -0.153  -0.262  -0.450  -0.439  -0.203  -0.370  -0.368
139   I        -0.645  -0.491  -0.646  -0.718  -0.459  -0.681  -0.692  -0.486  -0.651
140   N        -1.642  -1.628  -1.504  -1.373  -1.326  -1.172  -1.303  -1.258  -1.101
141   A        -0.045  -0.130  -0.098  -0.087  -0.220  -0.181  -0.203  -0.311  -0.279
142   S         0.603   0.520   0.573   0.419   0.292   0.383   0.407   0.221   0.263
143   T        -0.727  -0.673  -0.674  -0.854  -0.763  -0.734  -0.814  -0.744  -0.694
144   H        -0.378  -0.563  -0.660   0.004  -0.248  -0.457  -0.326  -0.553  -0.666
145   P         0.958   0.993   0.788   1.155   1.215   0.913   1.018   1.068   0.687
146   T         0.603   0.520   0.573   0.449   0.272   0.315   0.407   0.221   0.263
147   H         0.958   0.850   0.767   1.271   1.159   1.043   1.018   0.831   0.646
148   V         1.681   1.744   1.849   1.551   1.647   1.819   1.873   1.971   2.161
149   T         0.603   0.651   0.667   0.477   0.549   0.550   0.407   0.474   0.453
150   K         0.958   0.903   0.783   1.031   0.983   0.815   1.018   0.921   0.677
151   F         0.958   0.850   0.767   1.214   1.101   0.990   1.018   0.831   0.646
152   H         0.270   0.074  -0.044   0.621   0.356   0.152   0.285   0.001  -0.192
153   T        -0.045   0.279  -0.042   0.047   0.535   0.049  -0.203   0.273  -0.193
154   Q        -0.645  -0.452  -0.631  -0.531  -0.242  -0.456  -0.692  -0.433  -0.633
155   D        -1.184  -1.270  -1.174  -1.047  -1.161  -1.014  -1.058  -1.108  -0.977
156   N        -0.394  -0.334  -0.194  -0.664  -0.580  -0.369  -0.692  -0.605  -0.422
157   K        -0.394  -0.289  -0.184  -0.630  -0.443  -0.297  -0.692  -0.538  -0.404
158   I        -0.045   0.121  -0.048  -0.048   0.176  -0.031  -0.203   0.007  -0.203
159   L         0.958   0.903   0.783   0.904   0.853   0.697   1.018   0.921   0.677
160   A        -1.310  -1.220  -1.165  -1.422  -1.253  -1.174  -1.180  -1.074  -0.970
161   T         0.412   0.435   0.537   0.053   0.056   0.194   0.041   0.052   0.188
162   A        -0.187  -0.245  -0.158  -0.309  -0.358  -0.194  -0.448  -0.501  -0.378
163   S         0.958   1.146   0.808   0.881   1.116   0.709   1.018   1.303   0.724
164   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
165   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
166   R         0.603   0.520   0.573   0.540   0.376   0.425   0.407   0.221   0.263
167   V        -1.184  -1.158  -1.153  -1.241  -1.179  -1.147  -1.058  -1.013  -0.959
168   T        -0.045   0.084  -0.021  -0.238  -0.013  -0.205  -0.203   0.013  -0.160
169   R         0.603   0.585   0.590   0.540   0.499   0.460   0.407   0.349   0.297
170   L         0.412   0.452   0.548  -0.031   0.019   0.157   0.041   0.086   0.211
171   W         0.412   0.461   0.562   0.501   0.573   0.715   0.041   0.105   0.240
172   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
173   I        -0.045  -0.000  -0.127  -0.093  -0.114  -0.301  -0.203  -0.200  -0.331
174   S         0.270   0.152  -0.023   0.251   0.101  -0.154   0.285   0.111  -0.161
175   N        -1.310  -1.200  -1.161  -1.245  -1.139  -1.043  -1.180  -1.056  -0.966
176   A        -1.184  -1.270  -1.174  -1.222  -1.338  -1.208  -1.058  -1.108  -0.977
177   Y        -0.852  -0.844  -0.746  -0.911  -0.949  -0.816  -0.936  -0.903  -0.771
178   E        -0.141  -0.226  -0.203  -0.102  -0.258  -0.261  -0.316  -0.450  -0.431
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   P         0.958   0.903   0.783   1.143   1.079   0.877   1.018   0.921   0.677
181   Q        -1.184  -1.158  -1.134  -1.119  -1.111  -1.096  -1.058  -1.015  -0.940
182   L        -1.184  -1.227  -1.158  -1.199  -1.209  -1.091  -1.058  -1.075  -0.963
183   E        -0.645  -0.765  -0.681  -0.537  -0.718  -0.613  -0.692  -0.807  -0.699
184   L         0.352   0.430   0.543   0.042   0.205   0.361  -0.081   0.042   0.200
185   T        -1.517  -1.603  -1.525  -1.381  -1.552  -1.413  -1.180  -1.233  -1.116
186   G         0.270   0.318   0.029   0.447   0.511   0.120   0.285   0.349  -0.081
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   A         0.352   0.446   0.550   0.169   0.360   0.503  -0.081   0.075   0.216
190   T        -1.642  -1.366  -1.481  -1.518  -1.094  -1.296  -1.303  -1.059  -1.084
191   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
192   Y         1.681   1.744   1.849   1.860   1.956   2.123   1.873   1.971   2.161
193   V         0.603   0.651   0.667   0.422   0.495   0.511   0.407   0.474   0.453
194   R         1.681   1.744   1.849   1.704   1.801   1.970   1.873   1.971   2.161
195   T        -0.187  -0.122  -0.125  -0.450  -0.335  -0.286  -0.448  -0.340  -0.333
196   L        -0.977  -0.883  -0.763  -1.334  -1.167  -0.990  -1.058  -0.940  -0.787
197   S        -1.310  -1.291  -1.163  -1.208  -1.205  -1.017  -1.180  -1.126  -0.968
198   F         0.958   0.903   0.783   1.214   1.170   1.014   1.018   0.921   0.677
199   I        -0.394  -0.363  -0.230  -0.567  -0.476  -0.287  -0.692  -0.644  -0.470
200   P         1.681   1.744   1.849   1.777   1.873   2.041   1.873   1.971   2.161
201   A        -0.869  -0.815  -0.761  -0.938  -0.863  -0.759  -0.950  -0.877  -0.785
202   A        -1.184  -1.227  -1.158  -1.177  -1.256  -1.129  -1.058  -1.075  -0.963
203   P        -0.645  -0.787  -0.706  -0.562  -0.803  -0.708  -0.692  -0.839  -0.729
204   H        -0.187  -0.118  -0.107  -0.142   0.005  -0.002  -0.448  -0.302  -0.295
205   L        -0.378  -0.332  -0.585  -0.330  -0.282  -0.613  -0.326  -0.270  -0.574
206   V        -0.313  -0.331  -0.212  -0.638  -0.701  -0.516  -0.570  -0.601  -0.445
207   A        -0.187  -0.019  -0.101  -0.481  -0.222  -0.318  -0.448  -0.208  -0.295
208   T        -0.045  -0.118  -0.153  -0.180  -0.355  -0.415  -0.203  -0.333  -0.367
209   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
210   S        -0.045  -0.090  -0.088  -0.126  -0.177  -0.155  -0.203  -0.256  -0.263
211   Y         1.681   1.744   1.849   1.860   1.956   2.123   1.873   1.971   2.161
212   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
213   G         0.958   0.850   0.767   1.027   0.870   0.727   1.018   0.831   0.646
214   L        -1.517  -1.203  -1.437  -1.431  -0.934  -1.341  -1.180  -0.862  -1.042
215   I        -0.045   0.135  -0.083  -0.198   0.053  -0.268  -0.203   0.031  -0.266
216   R         1.681   1.744   1.849   1.704   1.801   1.970   1.873   1.971   2.161
217   L        -0.045  -0.130  -0.098  -0.222  -0.348  -0.310  -0.203  -0.311  -0.279
218   Y        -0.645  -0.664  -0.699  -0.364  -0.409  -0.453  -0.692  -0.726  -0.720
219   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
220   T        -0.645  -0.618  -0.664  -0.703  -0.714  -0.748  -0.692  -0.675  -0.682
221   R         1.681   1.744   1.849   1.704   1.801   1.970   1.873   1.971   2.161
222   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   S        -1.642  -1.566  -1.489  -1.656  -1.537  -1.403  -1.303  -1.211  -1.089
224   G        -0.768  -0.708  -0.708  -0.814  -0.729  -0.741  -0.839  -0.773  -0.731
225   S        -1.642  -1.622  -1.503  -1.583  -1.510  -1.324  -1.303  -1.249  -1.099
226   T        -1.642  -1.649  -1.513  -1.523  -1.505  -1.304  -1.303  -1.270  -1.107
227   P        -0.645  -0.776  -0.705  -0.606  -0.831  -0.746  -0.692  -0.821  -0.723
228   I        -0.313  -0.093  -0.161  -0.516  -0.180  -0.286  -0.570  -0.249  -0.371
229   Y        -1.974  -1.850  -1.826  -1.752  -1.629  -1.522  -1.425  -1.306  -1.217
230   S        -0.394  -0.337  -0.197  -0.798  -0.711  -0.498  -0.692  -0.610  -0.427
231   L         0.352   0.446   0.550   0.042   0.249   0.384  -0.081   0.075   0.216
232   N        -1.642  -1.610  -1.504  -1.599  -1.579  -1.427  -1.303  -1.244  -1.101
233   H         0.412   0.461   0.562   0.408   0.490   0.623   0.041   0.105   0.240
234   D        -0.727  -0.795  -0.680  -0.755  -0.842  -0.658  -0.814  -0.851  -0.701
235   Q        -1.642  -1.609  -1.530  -1.373  -1.293  -1.215  -1.303  -1.242  -1.120
236   P         0.958   0.903   0.783   1.155   1.093   0.904   1.018   0.921   0.677
237   V         0.603   0.520   0.573   0.422   0.273   0.348   0.407   0.221   0.263
238   E         0.958   0.903   0.783   1.128   1.073   0.892   1.018   0.921   0.677
239   N        -0.645  -0.673  -0.666  -0.566  -0.585  -0.602  -0.692  -0.687  -0.675
240   V        -0.045   0.090  -0.075  -0.198  -0.001  -0.254  -0.203  -0.019  -0.250
241   I        -0.378   0.034  -0.544  -0.381   0.176  -0.636  -0.326   0.206  -0.522
242   A        -0.045  -0.118  -0.153  -0.029  -0.150  -0.155  -0.203  -0.333  -0.367
243   V        -0.911  -0.872  -0.740  -1.119  -1.045  -0.845  -0.998  -0.927  -0.764
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   S         0.270   0.152  -0.023   0.272   0.116  -0.109   0.285   0.111  -0.161
246   P        -0.645  -0.727  -0.706  -0.539  -0.710  -0.676  -0.692  -0.785  -0.729
247   T        -0.378  -0.505  -0.604  -0.250  -0.435  -0.608  -0.326  -0.478  -0.597
248   Q        -0.187  -0.047  -0.105  -0.247  -0.004  -0.060  -0.448  -0.212  -0.292
249   I        -0.045   0.064  -0.103  -0.260  -0.149  -0.359  -0.203  -0.092  -0.294
250   V        -0.645  -0.634  -0.692  -0.824  -0.848  -0.907  -0.692  -0.693  -0.714
251   S         0.958   0.850   0.767   0.859   0.716   0.593   1.018   0.831   0.646
252   C         0.412   0.614   0.634   0.293   0.592   0.634   0.041   0.405   0.387
253   G         0.958   0.850   0.767   1.047   0.900   0.773   1.018   0.831   0.646
254   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
255   N        -0.045   0.008  -0.059   0.050   0.145   0.005  -0.203  -0.097  -0.219
256   N        -1.974  -1.942  -1.831  -1.678  -1.676  -1.491  -1.425  -1.367  -1.221
257   F        -0.394  -0.346  -0.222  -0.601  -0.542  -0.351  -0.692  -0.620  -0.459
258   K         0.958   0.850   0.767   0.989   0.845   0.691   1.018   0.831   0.646
259   V        -0.045  -0.018  -0.079  -0.176  -0.133  -0.221  -0.203  -0.162  -0.250
260   W         0.958   0.850   0.767   1.283   1.137   0.976   1.018   0.831   0.646
261   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
262   L         0.958   0.993   0.788   0.921   0.983   0.742   1.018   1.068   0.687
263   T        -0.045  -0.164  -0.140  -0.133  -0.348  -0.305  -0.203  -0.388  -0.349
264   S        -0.852  -0.825  -0.748  -1.125  -1.063  -0.936  -0.936  -0.887  -0.772
265   N        -1.184  -1.116  -1.105  -1.018  -0.920  -0.877  -1.058  -0.960  -0.911
266   K        -0.313  -0.264  -0.181  -0.575  -0.502  -0.389  -0.570  -0.501  -0.400
267   K        -1.184  -1.078  -1.126  -1.058  -0.845  -0.966  -1.058  -0.921  -0.932
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   L        -0.187  -0.200  -0.138  -0.392  -0.395  -0.313  -0.448  -0.440  -0.353
271   Y        -1.974  -1.779  -1.796  -1.488  -1.259  -1.218  -1.425  -1.248  -1.197
272   E        -0.645  -0.796  -0.709  -0.551  -0.790  -0.685  -0.692  -0.848  -0.731
273   R        -0.727  -0.739  -0.702  -0.816  -0.811  -0.711  -0.814  -0.787  -0.721
274   G        -1.642  -1.560  -1.512  -1.536  -1.452  -1.364  -1.303  -1.211  -1.106
275   N         1.681   1.744   1.849   1.788   1.891   2.053   1.873   1.971   2.161
276   F         0.603   0.520   0.573   0.716   0.580   0.639   0.407   0.221   0.263
277   N        -1.184  -1.057  -1.134  -1.065  -0.882  -1.027  -1.058  -0.931  -0.943
278   K         1.681   1.744   1.849   1.651   1.750   1.918   1.873   1.971   2.161
279   A        -0.045   0.039  -0.091  -0.180  -0.124  -0.297  -0.203  -0.137  -0.279
280   V        -0.378  -0.423  -0.592  -0.333  -0.396  -0.655  -0.326  -0.381  -0.582
281   T         1.681   1.744   1.849   1.643   1.740   1.909   1.873   1.971   2.161
282   C         0.270   0.246   0.005   0.655   0.607   0.211   0.285   0.237  -0.118
283   L         1.681   1.744   1.849   1.521   1.617   1.789   1.873   1.971   2.161
284   D        -1.310  -1.123  -1.147  -1.367  -1.163  -1.104  -1.180  -0.992  -0.955
285   Y        -1.184  -1.270  -1.174  -0.891  -1.021  -0.880  -1.058  -1.108  -0.977
286   V        -0.645  -0.673  -0.666  -0.713  -0.703  -0.727  -0.692  -0.687  -0.675
287   E        -1.310  -1.117  -1.156  -1.245  -1.017  -1.015  -1.180  -0.987  -0.963
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   Q        -1.974  -1.870  -1.799  -1.771  -1.627  -1.533  -1.425  -1.318  -1.199
298   S        -0.645  -0.752  -0.696  -0.770  -0.909  -0.807  -0.692  -0.800  -0.718
299   A        -0.852  -0.685  -0.726  -1.001  -0.760  -0.815  -0.936  -0.754  -0.749
300   L         0.270   0.152  -0.023   0.257   0.095  -0.164   0.285   0.111  -0.161
301   I        -1.184  -1.121  -1.100  -1.229  -1.133  -1.058  -1.058  -0.982  -0.913
302   A        -0.313  -0.331  -0.212  -0.655  -0.748  -0.564  -0.570  -0.601  -0.445
303   S         0.412   0.614   0.634   0.095   0.469   0.466   0.041   0.405   0.387
304   S         0.958   0.903   0.783   0.867   0.801   0.637   1.018   0.921   0.677
305   L         1.681   1.744   1.849   1.521   1.617   1.789   1.873   1.971   2.161
306   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
307   G         0.958   0.929   0.799   1.027   0.986   0.785   1.018   0.964   0.707
308   H         0.958   0.929   0.799   1.229   1.209   1.003   1.018   0.964   0.707
309   V         0.958   0.929   0.799   0.923   0.901   0.727   1.018   0.964   0.707
310   K         1.681   1.744   1.849   1.651   1.750   1.918   1.873   1.971   2.161
311   V         0.412   0.492   0.554   0.101   0.224   0.316   0.041   0.166   0.222
312   F         0.958   0.903   0.783   1.202   1.155   0.988   1.018   0.921   0.677
313   D        -0.378  -0.445  -0.620  -0.165  -0.254  -0.546  -0.326  -0.420  -0.616
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   P        -0.141  -0.226  -0.203  -0.175  -0.359  -0.389  -0.316  -0.450  -0.431
316   L        -1.184  -1.270  -1.174  -1.372  -1.485  -1.316  -1.058  -1.108  -0.977
317   D        -0.852  -0.637  -0.694  -1.048  -0.737  -0.804  -0.936  -0.685  -0.714
318   N         0.270   0.200  -0.007   0.499   0.417   0.057   0.285   0.183  -0.136
319   F         0.352   0.446   0.550   0.342   0.520   0.663  -0.081   0.075   0.216
320   Q        -0.645  -0.685  -0.700  -0.511  -0.579  -0.611  -0.692  -0.740  -0.721
321   V         0.958   1.146   0.808   0.934   1.173   0.764   1.018   1.303   0.724
322   K        -0.645  -0.727  -0.706  -0.702  -0.853  -0.810  -0.692  -0.785  -0.729
323   F        -0.378  -0.563  -0.660  -0.032  -0.302  -0.464  -0.326  -0.553  -0.666
324   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
325   W         0.270   0.074  -0.044   0.685   0.409   0.201   0.285   0.001  -0.192
326   K         1.681   1.744   1.849   1.651   1.750   1.918   1.873   1.971   2.161
327   F         0.412   0.418   0.537   0.391   0.390   0.569   0.041   0.016   0.187
328   S        -0.187  -0.243  -0.153  -0.456  -0.506  -0.347  -0.448  -0.497  -0.371
329   G        -0.045   0.121  -0.081  -0.214  -0.000  -0.250  -0.203   0.014  -0.263
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   P        -0.394  -0.256  -0.188  -0.567  -0.351  -0.243  -0.692  -0.512  -0.413
332   V         0.603   0.520   0.573   0.422   0.273   0.348   0.407   0.221   0.263
333   L         1.681   1.744   1.849   1.521   1.617   1.789   1.873   1.971   2.161
334   S         0.958   0.993   0.788   0.907   0.966   0.736   1.018   1.068   0.687
335   C        -0.378  -0.563  -0.660   0.078  -0.203  -0.404  -0.326  -0.553  -0.666
336   A        -0.187  -0.157  -0.120  -0.394  -0.314  -0.275  -0.448  -0.354  -0.313
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   V         0.270   0.200  -0.007   0.301   0.211  -0.080   0.285   0.183  -0.136
339   S         0.958   0.850   0.767   0.859   0.716   0.593   1.018   0.831   0.646
340   P         0.895   0.780   0.726   1.061   0.900   0.794   0.916   0.708   0.568
341   S         0.390   0.416   0.536   0.014   0.049   0.255  -0.003   0.014   0.186
342   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   Q        -1.148  -1.242  -1.177  -0.896  -1.033  -0.969  -0.998  -1.080  -0.979
345   G        -0.852  -0.884  -0.748  -0.866  -0.889  -0.688  -0.936  -0.942  -0.772
346   N        -1.184  -1.151  -1.103  -1.138  -1.082  -0.975  -1.058  -0.992  -0.909
347   R        -0.727  -0.742  -0.692  -0.703  -0.676  -0.576  -0.814  -0.801  -0.714
348   H         0.958   0.903   0.783   1.249   1.200   1.020   1.018   0.921   0.677
349   L        -0.187  -0.130  -0.124  -0.372  -0.276  -0.239  -0.448  -0.354  -0.329
350   V         0.958   0.850   0.767   0.908   0.771   0.640   1.018   0.831   0.646
351   A        -0.045  -0.038  -0.132  -0.165  -0.230  -0.347  -0.203  -0.242  -0.337
352   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
353   L         0.603   0.520   0.573   0.454   0.334   0.429   0.407   0.221   0.263
354   S        -0.727  -0.767  -0.691  -0.956  -0.977  -0.872  -0.814  -0.826  -0.713
355   S         0.958   0.903   0.783   0.881   0.824   0.670   1.018   0.921   0.677
356   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
357   L        -0.645  -0.744  -0.697  -0.791  -0.939  -0.868  -0.692  -0.778  -0.718
358   L        -0.045  -0.018  -0.079  -0.222  -0.178  -0.279  -0.203  -0.162  -0.250
359   A         0.352   0.446   0.550  -0.104   0.034   0.204  -0.081   0.075   0.216
360   I        -0.378  -0.563  -0.660  -0.172  -0.461  -0.664  -0.326  -0.553  -0.666
361   R         0.958   1.146   0.808   1.063   1.311   0.861   1.018   1.303   0.724
362   T         1.681   1.744   1.849   1.643   1.740   1.909   1.873   1.971   2.161
363   K        -0.187  -0.161  -0.142  -0.324  -0.270  -0.209  -0.448  -0.408  -0.357
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   K         0.958   0.903   0.783   1.018   0.963   0.785   1.018   0.921   0.677
372   K        -0.645  -0.776  -0.705  -0.673  -0.867  -0.764  -0.692  -0.821  -0.723
373   E        -0.977  -1.039  -1.114  -0.754  -0.858  -1.032  -0.814  -0.876  -0.918
374   K        -0.645  -0.722  -0.687  -0.598  -0.705  -0.647  -0.692  -0.764  -0.702
375   R        -0.187  -0.198  -0.141  -0.324  -0.303  -0.214  -0.448  -0.436  -0.356
376   S        -1.642  -1.555  -1.512  -1.665  -1.564  -1.466  -1.303  -1.208  -1.106
377   S        -0.645  -0.619  -0.656  -0.797  -0.783  -0.785  -0.692  -0.660  -0.665
378   D        -1.974  -1.850  -1.826  -1.697  -1.526  -1.504  -1.425  -1.306  -1.217
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -0.874  -0.799  -0.717  -1.094  -0.970  -0.855  -0.941  -0.842  -0.734
382   -        -1.405  -1.323  -1.199  -1.308  -1.147  -1.004  -1.254  -1.152  -0.999
383   K         0.017   0.098  -0.056  -0.140  -0.039  -0.289  -0.081   0.021  -0.211
384   E        -1.312  -1.185  -1.145  -1.483  -1.321  -1.230  -1.167  -1.026  -0.948
385   N        -0.258  -0.145  -0.178  -0.339  -0.216  -0.211  -0.515  -0.392  -0.402
386   A        -1.312  -1.199  -1.145  -1.399  -1.252  -1.152  -1.167  -1.040  -0.949
387   P        -1.755  -1.639  -1.545  -1.723  -1.599  -1.414  -1.384  -1.262  -1.130
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   A        -0.702  -0.737  -0.713  -0.791  -0.895  -0.837  -0.733  -0.777  -0.729
393   S        -1.312  -1.121  -1.154  -1.364  -1.079  -1.127  -1.167  -0.964  -0.958
394   F        -1.642  -1.536  -1.502  -1.523  -1.372  -1.325  -1.303  -1.192  -1.099
395   N        -1.974  -1.889  -1.809  -1.818  -1.737  -1.599  -1.425  -1.333  -1.206
396   K        -0.977  -1.028  -1.110  -0.843  -0.954  -1.082  -0.814  -0.866  -0.914
397   N        -1.642  -1.562  -1.500  -1.513  -1.415  -1.324  -1.303  -1.213  -1.098
398   A        -1.184  -1.168  -1.118  -1.137  -1.116  -1.012  -1.058  -1.014  -0.928
399   K         0.958   0.929   0.799   0.996   0.971   0.764   1.018   0.964   0.707
400   S        -0.045  -0.177  -0.153  -0.246  -0.444  -0.408  -0.203  -0.387  -0.367
401   N        -0.187  -0.192  -0.143  -0.266  -0.277  -0.199  -0.448  -0.436  -0.357
402   N        -0.768  -0.866  -0.738  -0.751  -0.910  -0.728  -0.839  -0.923  -0.762
403   F        -0.768  -0.853  -0.751  -0.576  -0.679  -0.543  -0.839  -0.911  -0.775
404   Q        -0.768  -0.722  -0.724  -0.725  -0.697  -0.675  -0.839  -0.779  -0.746
405   R        -0.531  -0.628  -0.690  -0.390  -0.560  -0.664  -0.520  -0.645  -0.702
406   M         0.154  -0.033  -0.106   0.445   0.120  -0.069   0.118  -0.164  -0.286
407   M         0.154  -0.033  -0.106   0.491   0.208   0.029   0.118  -0.164  -0.286
408   R        -0.152  -0.217  -0.173  -0.229  -0.368  -0.293  -0.360  -0.467  -0.396
409   G         0.895   0.730   0.709   0.958   0.697   0.637   0.916   0.618   0.535
410   S        -0.977  -1.172  -1.132  -0.881  -1.116  -1.049  -0.814  -1.005  -0.936
411   E        -1.642  -1.604  -1.529  -1.456  -1.422  -1.289  -1.303  -1.239  -1.119
412   Y         0.958   0.850   0.767   1.201   1.056   0.897   1.018   0.831   0.646
413   Q        -1.642  -1.585  -1.501  -1.583  -1.522  -1.390  -1.303  -1.221  -1.097
414   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
415   D        -0.187  -0.047  -0.105  -0.229   0.040  -0.048  -0.448  -0.212  -0.292
416   Q        -1.310  -1.159  -1.165  -1.175  -0.927  -0.960  -1.180  -1.019  -0.970
417   E         0.270   0.074  -0.044   0.479   0.203  -0.018   0.285   0.001  -0.192
418   H        -0.045  -0.176  -0.141   0.138  -0.082  -0.047  -0.203  -0.399  -0.351
419   I        -1.184  -1.198  -1.149  -1.070  -1.100  -1.005  -1.058  -1.049  -0.955
420   I         0.958   0.903   0.783   1.132   1.075   0.922   1.018   0.921   0.677
421   H        -0.394  -0.323  -0.214  -0.519  -0.438  -0.290  -0.692  -0.587  -0.447
422   N        -0.727  -0.641  -0.675  -0.626  -0.484  -0.516  -0.814  -0.699  -0.694
423   D        -0.852  -0.884  -0.748  -0.998  -1.046  -0.839  -0.936  -0.942  -0.772
424   K        -1.184  -1.262  -1.153  -1.182  -1.298  -1.125  -1.058  -1.101  -0.959
425   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
426   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
427   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
428   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
429   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
430   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
431   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
432   V        -1.671  -1.634  -1.538  -1.650  -1.579  -1.426  -1.317  -1.260  -1.126
433   R        -1.291  -1.177  -1.141  -1.276  -1.112  -1.045  -1.158  -1.030  -0.949
434   S        -1.310  -1.184  -1.156  -1.227  -1.034  -1.006  -1.180  -1.038  -0.964
435   Q        -0.852  -0.825  -0.748  -0.856  -0.818  -0.699  -0.936  -0.887  -0.772
436   R        -0.727  -0.777  -0.683  -0.803  -0.850  -0.712  -0.814  -0.826  -0.698
437   R         0.412   0.513   0.570   0.168   0.341   0.404   0.041   0.208   0.256
438   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
439   M         0.270   0.374   0.051   0.317   0.448   0.067   0.285   0.422  -0.048
440   R         0.352   0.430   0.543   0.055   0.184   0.352  -0.081   0.042   0.200
441   A        -1.642  -1.474  -1.499  -1.488  -1.231  -1.301  -1.303  -1.133  -1.097
442   F        -0.378  -0.544  -0.617  -0.009  -0.226  -0.350  -0.326  -0.529  -0.613
443   E        -0.378  -0.610  -0.639  -0.072  -0.385  -0.451  -0.326  -0.609  -0.641
444   R        -0.645  -0.682  -0.679  -0.583  -0.625  -0.627  -0.692  -0.720  -0.698
445   N        -1.642  -1.543  -1.503  -1.450  -1.375  -1.236  -1.303  -1.196  -1.100
446   I        -0.727  -0.777  -0.683  -0.771  -0.803  -0.641  -0.814  -0.826  -0.698
447   N        -0.977  -1.172  -1.132  -0.771  -1.109  -1.122  -0.814  -1.005  -0.936
448   Q        -1.184  -1.191  -1.150  -1.135  -1.191  -1.129  -1.058  -1.044  -0.956
449   F         0.270   0.096  -0.006   0.578   0.352   0.192   0.285   0.033  -0.135
450   K        -0.187  -0.215  -0.142  -0.290  -0.291  -0.153  -0.448  -0.467  -0.357
451   W         0.534   0.466   0.557   0.721   0.585   0.707   0.278   0.115   0.229
452   S        -0.152  -0.145  -0.138  -0.421  -0.424  -0.405  -0.360  -0.351  -0.348
453   E        -0.245  -0.271  -0.150  -0.356  -0.386  -0.204  -0.520  -0.525  -0.364
454   A         0.895   0.781   0.740   0.947   0.808   0.775   0.916   0.710   0.595
455   L         1.681   1.744   1.849   1.510   1.603   1.778   1.873   1.971   2.161
456   D         1.681   1.744   1.849   1.719   1.816   1.985   1.873   1.971   2.161
457   N        -1.291  -1.131  -1.147  -1.241  -1.032  -0.971  -1.158  -0.991  -0.954
458   A         0.534   0.466   0.557   0.295   0.121   0.251   0.278   0.115   0.229
459   F         0.371   0.419   0.544   0.106   0.126   0.317  -0.041   0.020   0.202
460   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
461   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
462   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
463   V        -1.312  -1.297  -1.192  -1.462  -1.463  -1.274  -1.167  -1.132  -0.993
464   P        -0.531  -0.593  -0.659  -0.323  -0.412  -0.574  -0.520  -0.590  -0.664
465   G         0.895   0.781   0.740   0.986   0.827   0.770   0.916   0.710   0.595
466   M        -0.702  -0.820  -0.751  -0.432  -0.637  -0.590  -0.733  -0.870  -0.773
467   A        -1.148  -1.258  -1.177  -1.030  -1.190  -1.051  -0.998  -1.092  -0.979
468   K        -0.152  -0.201  -0.175  -0.244  -0.322  -0.302  -0.360  -0.447  -0.399
469   E         0.534   0.466   0.557   0.427   0.254   0.366   0.278   0.115   0.229
470   L        -0.152  -0.160  -0.156  -0.384  -0.411  -0.373  -0.360  -0.391  -0.373
471   T        -0.531  -0.710  -0.702  -0.492  -0.789  -0.811  -0.520  -0.735  -0.716
472   L        -0.152  -0.197  -0.151  -0.443  -0.507  -0.442  -0.360  -0.416  -0.363
473   T         0.154   0.026  -0.061   0.156  -0.054  -0.247   0.118  -0.074  -0.219
474   V        -0.531  -0.484  -0.624  -0.491  -0.424  -0.604  -0.520  -0.464  -0.621
475   L         1.681   1.744   1.849   1.510   1.603   1.778   1.873   1.971   2.161
476   Q        -1.517  -1.603  -1.525  -1.216  -1.387  -1.277  -1.180  -1.233  -1.116
477   E         0.270   0.096  -0.006   0.517   0.287   0.128   0.285   0.033  -0.135
478   L         1.681   1.744   1.849   1.521   1.617   1.789   1.873   1.971   2.161
479   R        -0.645  -0.710  -0.681  -0.660  -0.756  -0.749  -0.692  -0.742  -0.699
480   K        -0.045  -0.164  -0.140  -0.030  -0.199  -0.163  -0.203  -0.388  -0.349
481   R         0.270   0.143   0.011   0.388   0.206  -0.044   0.285   0.102  -0.110
482   G         0.958   0.850   0.767   1.027   0.870   0.727   1.018   0.831   0.646
483   K         0.154  -0.043  -0.084   0.222  -0.079  -0.168   0.118  -0.173  -0.254
484   V        -0.388  -0.339  -0.231  -0.714  -0.684  -0.523  -0.679  -0.613  -0.471
485   R         0.895   1.083   0.785   0.971   1.228   0.814   0.916   1.209   0.681
486   V        -0.768  -0.830  -0.731  -0.895  -0.952  -0.794  -0.839  -0.887  -0.753
487   A         0.895   0.956   0.768   0.871   0.955   0.666   0.916   1.009   0.650
488   L         1.681   1.744   1.849   1.510   1.603   1.778   1.873   1.971   2.161
489   Y        -1.148  -1.184  -1.150  -0.929  -1.046  -1.014  -0.998  -1.027  -0.953
490   G         0.371   0.427   0.538   0.185   0.267   0.442  -0.041   0.035   0.190
491   R         1.681   1.744   1.849   1.695   1.790   1.960   1.873   1.971   2.161
492   D         1.681   1.744   1.849   1.719   1.816   1.985   1.873   1.971   2.161
493   E         0.895   0.832   0.754   1.042   0.967   0.839   0.916   0.799   0.621
494   S        -1.148  -1.258  -1.177  -1.275  -1.490  -1.342  -0.998  -1.092  -0.979
495   T         0.534   0.562   0.574   0.234   0.268   0.260   0.278   0.303   0.264
496   L         0.895   0.781   0.740   0.767   0.601   0.519   0.916   0.710   0.595
497   E        -0.152  -0.236  -0.168  -0.256  -0.432  -0.356  -0.360  -0.479  -0.389
498   P         1.681   1.744   1.849   1.804   1.902   2.068   1.873   1.971   2.161
499   L         0.895   0.956   0.768   0.805   0.898   0.646   0.916   1.009   0.650
500   L         0.154   0.070  -0.049   0.131   0.025  -0.136   0.118  -0.007  -0.199
501   N        -0.531  -0.628  -0.667  -0.267  -0.409  -0.495  -0.520  -0.636  -0.674
502   W         0.534   0.517   0.571   0.702   0.657   0.707   0.278   0.216   0.259
503   C        -1.148  -1.258  -1.177  -0.872  -1.145  -1.055  -0.998  -1.092  -0.979
504   L        -0.768  -0.810  -0.725  -0.931  -0.954  -0.816  -0.839  -0.867  -0.747
505   K         1.681   1.744   1.849   1.656   1.754   1.922   1.873   1.971   2.161
506   G        -1.184  -1.158  -1.153  -1.071  -1.025  -1.020  -1.058  -1.013  -0.959
507   I         0.958   1.098   0.806   1.084   1.271   0.856   1.018   1.231   0.720
508   E        -0.977  -1.172  -1.132  -0.755  -1.096  -1.068  -0.814  -1.005  -0.936
509   D         1.681   1.744   1.849   1.714   1.809   1.979   1.873   1.971   2.161
510   V        -0.645  -0.727  -0.706  -0.724  -0.823  -0.797  -0.692  -0.785  -0.729
511   R         0.958   0.929   0.799   1.063   1.040   0.845   1.018   0.964   0.707
512   S        -0.645  -0.767  -0.704  -0.653  -0.770  -0.643  -0.692  -0.821  -0.726
513   A        -0.768  -0.697  -0.697  -0.921  -0.840  -0.836  -0.839  -0.756  -0.717
514   S        -1.148  -1.091  -1.114  -0.947  -0.878  -0.938  -0.998  -0.939  -0.918
515   I        -0.768  -0.787  -0.707  -0.893  -0.947  -0.855  -0.839  -0.842  -0.730
516   V        -0.531  -0.684  -0.689  -0.508  -0.718  -0.724  -0.520  -0.705  -0.701
517   A        -0.388  -0.358  -0.231  -0.590  -0.532  -0.344  -0.679  -0.638  -0.471
518   D         0.895   0.832   0.754   1.014   0.940   0.820   0.916   0.799   0.621
519   W        -0.768  -0.749  -0.731  -0.600  -0.642  -0.581  -0.839  -0.804  -0.753
520   V        -0.768  -0.843  -0.721  -0.926  -1.042  -0.847  -0.839  -0.894  -0.743
521   A        -1.148  -1.163  -1.140  -1.132  -1.183  -1.146  -0.998  -1.007  -0.944
522   V         0.154  -0.043  -0.084   0.137  -0.134  -0.213   0.118  -0.173  -0.254
523   V        -0.531  -0.684  -0.689  -0.517  -0.763  -0.739  -0.520  -0.705  -0.701
524   L         0.154   0.170  -0.025   0.131   0.150  -0.100   0.118   0.120  -0.163
525   E         0.371   0.419   0.544   0.184   0.249   0.439  -0.041   0.020   0.202
526   L        -0.388  -0.298  -0.203  -0.472  -0.321  -0.193  -0.679  -0.561  -0.433
527   Y         1.681   1.744   1.849   1.865   1.963   2.129   1.873   1.971   2.161
528   G         0.154   0.026  -0.061   0.230   0.012  -0.151   0.118  -0.074  -0.219
529   N        -1.671  -1.586  -1.514  -1.640  -1.536  -1.389  -1.317  -1.225  -1.107
530   T        -1.148  -1.165  -1.137  -1.212  -1.232  -1.211  -0.998  -1.009  -0.941
531   L        -0.768  -0.724  -0.702  -0.984  -0.942  -0.884  -0.839  -0.787  -0.722
532   E        -1.291  -1.135  -1.158  -1.209  -0.993  -1.008  -1.158  -0.980  -0.963
533   S        -0.768  -0.571  -0.698  -0.868  -0.617  -0.769  -0.839  -0.641  -0.719
534   S         1.681   1.744   1.849   1.513   1.605   1.781   1.873   1.971   2.161
535   P        -0.531  -0.684  -0.689  -0.391  -0.684  -0.753  -0.520  -0.705  -0.701
536   V        -0.531  -0.710  -0.702  -0.457  -0.689  -0.652  -0.520  -0.735  -0.716
537   L         0.895   0.832   0.754   0.767   0.681   0.544   0.916   0.799   0.621
538   Q        -0.531  -0.380  -0.608  -0.309  -0.131  -0.433  -0.520  -0.346  -0.602
539   E         0.154  -0.043  -0.084   0.361   0.085   0.001   0.118  -0.173  -0.254
540   L        -1.671  -1.646  -1.535  -1.504  -1.492  -1.378  -1.317  -1.268  -1.123
541   M        -0.768  -0.717  -0.706  -0.776  -0.700  -0.619  -0.839  -0.783  -0.728
542   I        -0.911  -0.750  -0.736  -1.192  -0.991  -0.947  -0.998  -0.820  -0.760
543   D        -1.671  -1.599  -1.521  -1.670  -1.592  -1.460  -1.317  -1.235  -1.113
544   L         0.154   0.026  -0.061   0.166   0.012  -0.090   0.118  -0.074  -0.219
545   K        -1.291  -1.284  -1.157  -1.322  -1.294  -1.114  -1.158  -1.118  -0.961
546   T        -1.642  -1.613  -1.505  -1.487  -1.423  -1.280  -1.303  -1.246  -1.102
547   K        -0.645  -0.590  -0.644  -0.652  -0.538  -0.647  -0.692  -0.591  -0.654
548   V        -0.045   0.025  -0.100  -0.242  -0.171  -0.341  -0.203  -0.130  -0.288
549   R        -1.184  -1.227  -1.158  -1.141  -1.232  -1.108  -1.058  -1.075  -0.963
550   H        -1.642  -1.526  -1.502  -1.404  -1.239  -1.198  -1.303  -1.176  -1.098
551   E         1.681   1.744   1.849   1.761   1.859   2.026   1.873   1.971   2.161
552   I         0.352   0.427   0.553   0.011   0.115   0.315  -0.081   0.035   0.222
553   H        -1.642  -1.538  -1.502  -1.459  -1.336  -1.294  -1.303  -1.183  -1.098
554   K        -0.378  -0.505  -0.604  -0.239  -0.416  -0.597  -0.326  -0.478  -0.597
555   S        -0.645  -0.575  -0.641  -0.592  -0.495  -0.598  -0.692  -0.609  -0.646
556   K        -0.645  -0.622  -0.680  -0.625  -0.615  -0.676  -0.692  -0.688  -0.699
557   E        -0.378  -0.610  -0.639  -0.076  -0.389  -0.457  -0.326  -0.609  -0.641
558   A         0.958   0.993   0.788   0.977   1.026   0.718   1.018   1.068   0.687
559   Q        -0.852  -0.886  -0.744  -0.822  -0.860  -0.664  -0.936  -0.944  -0.770
560   R        -0.852  -0.783  -0.720  -0.890  -0.742  -0.684  -0.936  -0.823  -0.742
561   I         0.270   0.074  -0.044   0.445   0.157  -0.071   0.285   0.001  -0.192
562   E        -1.517  -1.603  -1.525  -1.163  -1.280  -1.176  -1.180  -1.233  -1.116
563   G         1.681   1.744   1.849   1.689   1.774   1.955   1.873   1.971   2.161
564   M         1.681   1.744   1.849   1.922   2.013   2.185   1.873   1.971   2.161
565   L         0.958   0.850   0.767   0.865   0.724   0.581   1.018   0.831   0.646
566   Q         0.352   0.430   0.543   0.200   0.336   0.496  -0.081   0.042   0.200
567   L         0.270   0.074  -0.044   0.268   0.002  -0.173   0.285   0.001  -0.192
568   L         1.681   1.744   1.849   1.521   1.617   1.789   1.873   1.971   2.161
569   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
570   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
571   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
572   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
573   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
574   T        -0.645  -0.787  -0.706  -0.730  -0.961  -0.843  -0.692  -0.839  -0.729
575   S        -0.852  -0.681  -0.729  -1.078  -0.854  -0.902  -0.936  -0.752  -0.753
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04305
Output conservation file - output/Q04305
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
