1     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    M         0.479   0.629   0.436   0.629   0.887   0.545   0.388   0.624   0.304
18    R         0.173   0.233   0.264   0.125   0.242   0.270  -0.136  -0.036   0.007
19    I        -0.640  -0.700  -0.675  -0.743  -0.842  -0.778  -0.660  -0.722  -0.683
20    I        -0.640  -0.545  -0.605  -0.897  -0.762  -0.842  -0.660  -0.523  -0.594
21    L        -0.640  -0.633  -0.641  -0.956  -0.939  -0.944  -0.660  -0.643  -0.640
22    C         0.173   0.233   0.264   0.032   0.091   0.159  -0.136  -0.036   0.007
23    D         1.798   1.846   1.877   1.928   2.012   2.060   1.960   2.025   2.075
24    T        -0.640  -0.700  -0.675  -0.644  -0.773  -0.736  -0.660  -0.722  -0.683
25    N         1.798   1.846   1.877   1.762   1.827   1.894   1.960   2.025   2.075
26    E        -0.640  -0.700  -0.675  -0.555  -0.648  -0.599  -0.660  -0.722  -0.683
27    V        -0.640  -0.700  -0.675  -0.682  -0.813  -0.755  -0.660  -0.722  -0.683
28    V         0.479   0.362   0.360   0.475   0.259   0.252   0.388   0.189   0.175
29    T        -1.453  -1.398  -1.381  -1.339  -1.264  -1.217  -1.184  -1.104  -1.069
30    N        -0.640  -0.633  -0.641  -0.608  -0.600  -0.590  -0.660  -0.643  -0.640
31    L        -1.453  -1.398  -1.381  -1.343  -1.182  -1.220  -1.184  -1.104  -1.069
32    W         0.479   0.629   0.436   0.703   0.961   0.604   0.388   0.624   0.304
33    Q        -1.453  -1.398  -1.381  -1.146  -1.051  -1.023  -1.184  -1.104  -1.069
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    E        -0.640  -0.554  -0.607  -0.483  -0.329  -0.428  -0.660  -0.535  -0.597
38    S        -1.453  -1.398  -1.381  -1.395  -1.296  -1.272  -1.184  -1.104  -1.069
39    I        -0.640  -0.465  -0.615  -0.970  -0.702  -0.921  -0.660  -0.417  -0.607
40    P        -0.640  -0.700  -0.675  -0.659  -0.743  -0.727  -0.660  -0.722  -0.683
41    H        -0.640  -0.465  -0.615  -0.620  -0.355  -0.568  -0.660  -0.417  -0.607
42    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    I        -0.640  -0.545  -0.605  -0.856  -0.724  -0.798  -0.660  -0.523  -0.594
45    Q        -0.640  -0.641  -0.643  -0.801  -0.796  -0.769  -0.660  -0.653  -0.643
46    N        -0.640  -0.465  -0.615  -0.646  -0.337  -0.607  -0.660  -0.417  -0.607
47    D        -1.453  -1.398  -1.381  -1.247  -1.168  -1.124  -1.184  -1.104  -1.069
48    K        -1.453  -1.398  -1.381  -1.295  -1.197  -1.172  -1.184  -1.104  -1.069
49    Y        -1.453  -1.398  -1.381  -1.307  -1.251  -1.185  -1.184  -1.104  -1.069
50    L        -0.640  -0.641  -0.643  -0.743  -0.737  -0.766  -0.660  -0.653  -0.643
51    C         0.173   0.233   0.264   0.129   0.230   0.267  -0.136  -0.036   0.007
52    I        -0.640  -0.633  -0.641  -0.724  -0.723  -0.709  -0.660  -0.643  -0.640
53    H         1.798   1.846   1.877   1.975   2.061   2.107   1.960   2.025   2.075
54    H         0.479   0.505   0.404   0.631   0.681   0.496   0.388   0.427   0.250
55    G         0.479   0.362   0.360   0.419   0.225   0.213   0.388   0.189   0.175
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    H        -1.453  -1.398  -1.381  -1.257  -1.139  -1.134  -1.184  -1.104  -1.069
65    L         0.479   0.362   0.360   0.163  -0.048  -0.043   0.388   0.189   0.175
66    Q         0.479   0.615   0.434   0.584   0.777   0.528   0.388   0.602   0.302
67    S         0.479   0.362   0.360   0.552   0.396   0.377   0.388   0.189   0.175
68    L        -0.640  -0.700  -0.675  -0.809  -0.849  -0.808  -0.660  -0.722  -0.683
69    M        -1.453  -1.398  -1.381  -1.362  -1.275  -1.240  -1.184  -1.104  -1.069
70    D        -1.453  -1.398  -1.381  -1.282  -1.160  -1.159  -1.184  -1.104  -1.069
71    S         0.173   0.233   0.264  -0.076   0.024   0.076  -0.136  -0.036   0.007
72    M         0.305   0.238   0.279   0.414   0.300   0.352   0.097  -0.027   0.034
73    R         0.305   0.238   0.279   0.346   0.207   0.256   0.097  -0.027   0.034
74    K        -0.778  -0.715  -0.705  -0.786  -0.670  -0.662  -0.835  -0.739  -0.720
75    G        -0.778  -0.715  -0.705  -0.900  -0.814  -0.776  -0.835  -0.739  -0.720
76    D        -0.778  -0.715  -0.705  -0.872  -0.787  -0.748  -0.835  -0.739  -0.720
77    A        -0.778  -0.715  -0.705  -0.745  -0.607  -0.620  -0.835  -0.739  -0.720
78    I        -0.778  -0.715  -0.705  -1.014  -0.896  -0.890  -0.835  -0.739  -0.720
79    H         0.305   0.238   0.279   0.304   0.148   0.218   0.097  -0.027   0.034
80    H        -0.778  -0.715  -0.705  -0.704  -0.576  -0.579  -0.835  -0.739  -0.720
81    G         1.798   1.846   1.877   1.756   1.841   1.887   1.960   2.025   2.075
82    H        -0.778  -0.732  -0.705  -0.929  -0.866  -0.805  -0.835  -0.760  -0.720
83    S        -0.640  -0.554  -0.607  -0.748  -0.587  -0.702  -0.660  -0.535  -0.597
84    Y        -0.640  -0.700  -0.675  -0.525  -0.606  -0.577  -0.660  -0.722  -0.683
85    A         0.173   0.233   0.264   0.070   0.183   0.215  -0.136  -0.036   0.007
86    I         1.798   1.846   1.877   1.683   1.742   1.815   1.960   2.025   2.075
87    V         1.798   1.846   1.877   1.840   1.916   1.971   1.960   2.025   2.075
88    S         0.479   0.362   0.360   0.537   0.377   0.354   0.388   0.189   0.175
89    P         1.798   1.846   1.877   1.846   1.933   1.977   1.960   2.025   2.075
90    G         0.479   0.362   0.360   0.485   0.327   0.312   0.388   0.189   0.175
91    N         1.798   1.846   1.877   1.762   1.827   1.894   1.960   2.025   2.075
92    S         1.798   1.846   1.877   1.822   1.914   1.954   1.960   2.025   2.075
93    Y        -0.640  -0.641  -0.643  -0.703  -0.768  -0.726  -0.660  -0.653  -0.643
94    G         0.479   0.362   0.360   0.419   0.225   0.213   0.388   0.189   0.175
95    Y         0.479   0.505   0.404   0.592   0.633   0.472   0.388   0.427   0.250
96    L         0.479   0.362   0.360   0.272   0.118   0.120   0.388   0.189   0.175
97    G         1.798   1.846   1.877   1.756   1.841   1.887   1.960   2.025   2.075
98    G         1.798   1.846   1.877   1.756   1.841   1.887   1.960   2.025   2.075
99    G         1.798   1.846   1.877   1.756   1.841   1.887   1.960   2.025   2.075
100   F         1.798   1.846   1.877   1.869   1.937   2.001   1.960   2.025   2.075
101   D         1.798   1.846   1.877   1.928   2.012   2.060   1.960   2.025   2.075
102   K         0.479   0.615   0.434   0.223   0.427   0.164   0.388   0.602   0.302
103   A         0.479   0.362   0.360   0.687   0.525   0.503   0.388   0.189   0.175
104   L         0.479   0.505   0.404   0.163   0.196   0.034   0.388   0.427   0.250
105   Y        -1.453  -1.398  -1.381  -1.411  -1.377  -1.289  -1.184  -1.104  -1.069
106   N         0.479   0.505   0.404   0.454   0.484   0.337   0.388   0.427   0.250
107   Y         0.479   0.362   0.360   0.622   0.449   0.440   0.388   0.189   0.175
108   F         0.479   0.362   0.360   0.504   0.279   0.280   0.388   0.189   0.175
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   G         0.479   0.362   0.360   0.474   0.309   0.295   0.388   0.189   0.175
113   G         0.479   0.362   0.360   0.419   0.225   0.213   0.388   0.189   0.175
114   K        -0.640  -0.700  -0.675  -0.555  -0.615  -0.601  -0.660  -0.722  -0.683
115   P         0.479   0.505   0.404   0.431   0.483   0.273   0.388   0.427   0.250
116   F         1.798   1.846   1.877   1.869   1.937   2.001   1.960   2.025   2.075
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   E         1.798   1.846   1.877   1.851   1.915   1.983   1.960   2.025   2.075
121   T        -1.453  -1.398  -1.381  -1.285  -1.190  -1.162  -1.184  -1.104  -1.069
122   W        -0.640  -0.700  -0.675  -0.417  -0.570  -0.515  -0.660  -0.722  -0.683
123   F        -0.640  -0.700  -0.675  -0.662  -0.805  -0.739  -0.660  -0.722  -0.683
124   R         0.479   0.362   0.360   0.729   0.578   0.544   0.388   0.189   0.175
125   N        -0.640  -0.545  -0.605  -0.654  -0.507  -0.588  -0.660  -0.523  -0.594
126   Q        -1.453  -1.398  -1.381  -1.204  -1.096  -1.081  -1.184  -1.104  -1.069
127   L         0.479   0.362   0.360   0.268   0.107   0.114   0.388   0.189   0.175
128   G        -0.640  -0.700  -0.675  -0.758  -0.880  -0.822  -0.660  -0.722  -0.683
129   G        -1.453  -1.398  -1.381  -1.304  -1.168  -1.181  -1.184  -1.104  -1.069
130   R        -0.640  -0.700  -0.675  -0.481  -0.558  -0.556  -0.660  -0.722  -0.683
131   Y         0.479   0.362   0.360   0.592   0.397   0.395   0.388   0.189   0.175
132   H        -0.640  -0.700  -0.675  -0.444  -0.524  -0.500  -0.660  -0.722  -0.683
133   T        -0.640  -0.700  -0.675  -0.577  -0.679  -0.652  -0.660  -0.722  -0.683
134   V         0.479   0.362   0.360   0.545   0.360   0.356   0.388   0.189   0.175
135   G        -0.640  -0.700  -0.675  -0.790  -0.919  -0.862  -0.660  -0.722  -0.683
136   S        -0.640  -0.700  -0.675  -0.669  -0.763  -0.732  -0.660  -0.722  -0.683
137   A        -0.640  -0.700  -0.675  -0.427  -0.510  -0.476  -0.660  -0.722  -0.683
138   T         0.479   0.362   0.360   0.586   0.389   0.371   0.388   0.189   0.175
139   V         0.479   0.362   0.360   0.573   0.403   0.399   0.388   0.189   0.175
140   V         0.479   0.615   0.434   0.374   0.565   0.309   0.388   0.602   0.302
141   D        -0.640  -0.700  -0.675  -0.517  -0.607  -0.577  -0.660  -0.722  -0.683
142   L         0.479   0.362   0.360   0.223   0.048   0.047   0.388   0.189   0.175
143   Q        -1.453  -1.398  -1.381  -1.369  -1.329  -1.246  -1.184  -1.104  -1.069
144   R        -0.640  -0.700  -0.675  -0.451  -0.554  -0.519  -0.660  -0.722  -0.683
145   C        -0.640  -0.700  -0.675  -0.562  -0.724  -0.672  -0.660  -0.722  -0.683
146   L         0.305   0.418   0.345   0.126   0.350   0.174   0.097   0.283   0.149
147   E        -0.778  -0.715  -0.705  -0.979  -0.830  -0.855  -0.835  -0.739  -0.720
148   E        -0.778  -0.715  -0.705  -1.131  -1.082  -1.008  -0.835  -0.739  -0.720
149   K        -0.778  -0.715  -0.705  -0.749  -0.615  -0.625  -0.835  -0.739  -0.720
150   T        -0.778  -0.715  -0.705  -0.949  -0.839  -0.825  -0.835  -0.739  -0.720
151   I        -0.778  -0.715  -0.705  -1.004  -0.889  -0.880  -0.835  -0.739  -0.720
152   E         1.798   1.846   1.877   1.834   1.892   1.966   1.960   2.025   2.075
153   C        -1.453  -1.398  -1.381  -1.405  -1.282  -1.282  -1.184  -1.104  -1.069
154   R         0.479   0.362   0.360   0.689   0.525   0.484   0.388   0.189   0.175
155   D         0.479   0.362   0.360   0.605   0.423   0.399   0.388   0.189   0.175
156   G        -0.640  -0.700  -0.675  -0.636  -0.707  -0.669  -0.660  -0.722  -0.683
157   I        -0.640  -0.700  -0.675  -0.883  -1.039  -0.954  -0.660  -0.722  -0.683
158   R        -0.640  -0.641  -0.643  -0.377  -0.359  -0.371  -0.660  -0.653  -0.643
159   Y         1.798   1.846   1.877   1.899   1.974   2.031   1.960   2.025   2.075
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   I         0.479   0.505   0.404   0.270   0.293   0.116   0.388   0.427   0.250
168   I         0.479   0.505   0.404   0.270   0.293   0.116   0.388   0.427   0.250
169   H         0.479   0.362   0.360   0.659   0.468   0.455   0.388   0.189   0.175
170   V         0.173   0.233   0.264  -0.121  -0.046   0.023  -0.136  -0.036   0.007
171   P         1.798   1.846   1.877   1.846   1.933   1.977   1.960   2.025   2.075
172   T         1.798   1.846   1.877   1.928   2.016   2.060   1.960   2.025   2.075
173   V         0.479   0.362   0.360   0.577   0.413   0.404   0.388   0.189   0.175
174   V         1.798   1.846   1.877   1.840   1.916   1.971   1.960   2.025   2.075
175   A        -0.640  -0.700  -0.675  -0.478  -0.570  -0.539  -0.660  -0.722  -0.683
176   P         1.798   1.846   1.877   1.846   1.933   1.977   1.960   2.025   2.075
177   S        -0.778  -0.732  -0.705  -0.827  -0.749  -0.703  -0.835  -0.760  -0.720
178   A        -0.778  -0.732  -0.705  -0.799  -0.723  -0.675  -0.835  -0.760  -0.720
179   P         1.798   1.846   1.877   1.792   1.857   1.924   1.960   2.025   2.075
180   I         0.305   0.258   0.279   0.147   0.055   0.107   0.097   0.008   0.034
181   F         0.305   0.393   0.310   0.305   0.444   0.306   0.097   0.241   0.089
182   N        -0.778  -0.732  -0.705  -0.715  -0.623  -0.590  -0.835  -0.760  -0.720
183   P        -0.778  -0.732  -0.705  -0.775  -0.677  -0.651  -0.835  -0.760  -0.720
184   Q        -0.778  -0.732  -0.705  -0.715  -0.605  -0.590  -0.835  -0.760  -0.720
185   N        -1.453  -1.398  -1.381  -1.279  -1.199  -1.156  -1.184  -1.104  -1.069
186   P         0.173   0.211   0.252   0.011   0.092   0.145  -0.136  -0.075  -0.015
187   L        -0.640  -0.700  -0.675  -0.970  -1.079  -1.007  -0.660  -0.722  -0.683
188   K         0.173   0.233   0.264   0.104   0.237   0.270  -0.136  -0.036   0.007
189   T         0.173   0.233   0.264   0.045   0.159   0.193  -0.136  -0.036   0.007
190   G         1.798   1.846   1.877   1.721   1.792   1.852   1.960   2.025   2.075
191   F        -0.640  -0.641  -0.643  -0.623  -0.670  -0.639  -0.660  -0.653  -0.643
192   E        -0.640  -0.700  -0.675  -0.547  -0.635  -0.590  -0.660  -0.722  -0.683
193   P        -0.640  -0.700  -0.675  -0.623  -0.702  -0.682  -0.660  -0.722  -0.683
194   V         0.479   0.362   0.360   0.425   0.195   0.176   0.388   0.189   0.175
195   F         1.798   1.846   1.877   1.869   1.937   2.001   1.960   2.025   2.075
196   N         0.173   0.233   0.264   0.002   0.125   0.173  -0.136  -0.036   0.007
197   A        -0.640  -0.700  -0.675  -0.429  -0.494  -0.479  -0.660  -0.722  -0.683
198   M        -0.640  -0.700  -0.675  -0.513  -0.636  -0.594  -0.660  -0.722  -0.683
199   W         1.798   1.846   1.877   2.124   2.206   2.256   1.960   2.025   2.075
200   N         1.798   1.846   1.877   1.762   1.827   1.894   1.960   2.025   2.075
201   A        -0.640  -0.633  -0.641  -0.654  -0.677  -0.683  -0.660  -0.643  -0.640
202   L        -0.640  -0.633  -0.641  -0.823  -0.776  -0.791  -0.660  -0.643  -0.640
203   M        -0.640  -0.700  -0.675  -0.461  -0.570  -0.529  -0.660  -0.722  -0.683
204   H        -0.640  -0.700  -0.675  -0.525  -0.651  -0.602  -0.660  -0.722  -0.683
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   S        -1.453  -1.398  -1.381  -1.304  -1.210  -1.181  -1.184  -1.104  -1.069
220   P         0.479   0.362   0.360   0.504   0.317   0.293   0.388   0.189   0.175
221   K        -1.453  -1.398  -1.381  -1.291  -1.202  -1.169  -1.184  -1.104  -1.069
222   D         0.173   0.233   0.264   0.066   0.157   0.216  -0.136  -0.036   0.007
223   I        -1.453  -1.398  -1.381  -1.402  -1.306  -1.279  -1.184  -1.104  -1.069
224   D        -0.640  -0.700  -0.675  -0.572  -0.698  -0.646  -0.660  -0.722  -0.683
225   G        -0.640  -0.700  -0.675  -0.695  -0.806  -0.743  -0.660  -0.722  -0.683
226   L         1.798   1.846   1.877   1.522   1.594   1.653   1.960   2.025   2.075
227   I         0.173   0.233   0.264  -0.121  -0.008   0.050  -0.136  -0.036   0.007
228   I         0.173   0.233   0.264  -0.359  -0.284  -0.215  -0.136  -0.036   0.007
229   P         1.798   1.846   1.877   1.846   1.933   1.977   1.960   2.025   2.075
230   G         1.798   1.846   1.877   1.756   1.841   1.887   1.960   2.025   2.075
231   L         0.479   0.362   0.360   0.163  -0.048  -0.043   0.388   0.189   0.175
232   C         0.479   0.362   0.360   0.696   0.501   0.474   0.388   0.189   0.175
233   T         1.798   1.846   1.877   1.928   2.016   2.060   1.960   2.025   2.075
234   G         1.798   1.846   1.877   1.756   1.841   1.887   1.960   2.025   2.075
235   Y         1.798   1.846   1.877   1.899   1.974   2.031   1.960   2.025   2.075
236   A         0.479   0.362   0.360   0.618   0.432   0.400   0.388   0.189   0.175
237   G         0.479   0.362   0.360   0.419   0.225   0.213   0.388   0.189   0.175
238   V         0.479   0.362   0.360   0.425   0.195   0.176   0.388   0.189   0.175
239   P         0.479   0.362   0.360   0.506   0.311   0.296   0.388   0.189   0.175
240   P        -0.640  -0.700  -0.675  -0.677  -0.788  -0.750  -0.660  -0.722  -0.683
241   I        -1.453  -1.398  -1.381  -1.372  -1.267  -1.249  -1.184  -1.104  -1.069
242   I         0.479   0.362   0.360   0.378   0.172   0.191   0.388   0.189   0.175
243   S         0.479   0.505   0.404   0.548   0.615   0.442   0.388   0.427   0.250
244   C         0.479   0.362   0.360   0.749   0.575   0.553   0.388   0.189   0.175
245   K         1.798   1.846   1.877   1.857   1.947   1.989   1.960   2.025   2.075
246   S        -0.640  -0.700  -0.675  -0.649  -0.757  -0.707  -0.660  -0.722  -0.683
247   M         1.798   1.846   1.877   1.998   2.094   2.130   1.960   2.025   2.075
248   A        -0.640  -0.700  -0.675  -0.557  -0.693  -0.639  -0.660  -0.722  -0.683
249   F         1.798   1.846   1.877   1.869   1.937   2.001   1.960   2.025   2.075
250   A         1.798   1.846   1.877   1.963   2.056   2.095   1.960   2.025   2.075
251   L         0.173   0.233   0.264  -0.359  -0.250  -0.186  -0.136  -0.036   0.007
252   R        -0.640  -0.633  -0.641  -0.476  -0.450  -0.484  -0.660  -0.643  -0.640
253   L         1.798   1.846   1.877   1.522   1.594   1.653   1.960   2.025   2.075
254   Y         0.479   0.505   0.404   0.592   0.633   0.472   0.388   0.427   0.250
255   M        -0.640  -0.700  -0.675  -0.493  -0.609  -0.569  -0.660  -0.722  -0.683
256   A         0.479   0.615   0.434   0.260   0.459   0.210   0.388   0.602   0.302
257   G        -1.453  -1.398  -1.381  -1.336  -1.229  -1.214  -1.184  -1.104  -1.069
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   D        -0.640  -0.700  -0.675  -0.515  -0.592  -0.574  -0.660  -0.722  -0.683
267   H        -1.453  -1.398  -1.381  -1.282  -1.160  -1.159  -1.184  -1.104  -1.069
268   I         0.173   0.233   0.264  -0.359  -0.284  -0.215  -0.136  -0.036   0.007
269   S         0.479   0.362   0.360   0.537   0.375   0.354   0.388   0.189   0.175
270   K        -0.640  -0.465  -0.615  -0.488  -0.181  -0.448  -0.660  -0.417  -0.607
271   E        -0.640  -0.700  -0.675  -0.706  -0.861  -0.788  -0.660  -0.722  -0.683
272   L         0.479   0.362   0.360   0.223   0.048   0.047   0.388   0.189   0.175
273   K        -0.640  -0.545  -0.605  -0.600  -0.440  -0.539  -0.660  -0.523  -0.594
274   N         0.479   0.362   0.360   0.444   0.251   0.248   0.388   0.189   0.175
275   V        -1.453  -1.398  -1.381  -1.425  -1.380  -1.302  -1.184  -1.104  -1.069
276   L         0.479   0.505   0.404   0.272   0.321   0.182   0.388   0.427   0.250
277   I         1.798   1.846   1.877   1.683   1.742   1.815   1.960   2.025   2.075
278   M         0.479   0.362   0.360   0.581   0.365   0.324   0.388   0.189   0.175
279   Y        -0.640  -0.700  -0.675  -0.471  -0.568  -0.510  -0.660  -0.722  -0.683
280   Y         0.479   0.615   0.434   0.573   0.773   0.508   0.388   0.602   0.302
281   L        -0.640  -0.700  -0.675  -0.809  -0.869  -0.808  -0.660  -0.722  -0.683
282   Q        -0.640  -0.641  -0.643  -0.662  -0.681  -0.655  -0.660  -0.653  -0.643
283   Y         0.479   0.362   0.360   0.588   0.401   0.390   0.388   0.189   0.175
284   P        -0.640  -0.700  -0.675  -0.515  -0.583  -0.548  -0.660  -0.722  -0.683
285   F         0.173   0.233   0.264   0.058   0.160   0.217  -0.136  -0.036   0.007
286   E        -0.640  -0.633  -0.641  -0.532  -0.499  -0.521  -0.660  -0.643  -0.640
287   P         0.479   0.362   0.360   0.537   0.363   0.341   0.388   0.189   0.175
288   F         0.479   0.362   0.360   0.454   0.216   0.204   0.388   0.189   0.175
289   F        -0.640  -0.641  -0.643  -0.737  -0.764  -0.728  -0.660  -0.653  -0.643
290   P        -1.453  -1.398  -1.381  -1.601  -1.486  -1.479  -1.184  -1.104  -1.069
291   E         0.479   0.362   0.360   0.437   0.194   0.187   0.388   0.189   0.175
292   S        -0.640  -0.700  -0.675  -0.631  -0.729  -0.684  -0.660  -0.722  -0.683
293   C         0.479   0.362   0.360   0.749   0.573   0.553   0.388   0.189   0.175
294   K        -0.640  -0.641  -0.643  -0.961  -0.987  -0.954  -0.660  -0.653  -0.643
295   I        -0.640  -0.554  -0.607  -0.608  -0.464  -0.550  -0.660  -0.535  -0.597
296   E         1.798   1.846   1.877   1.851   1.915   1.983   1.960   2.025   2.075
297   C         0.479   0.362   0.360   0.626   0.400   0.367   0.388   0.189   0.175
298   Q         0.479   0.362   0.360   0.670   0.477   0.466   0.388   0.189   0.175
299   K        -0.640  -0.633  -0.641  -0.515  -0.485  -0.502  -0.660  -0.643  -0.640
300   L        -0.640  -0.700  -0.675  -0.933  -1.026  -0.961  -0.660  -0.722  -0.683
301   G         0.479   0.362   0.360   0.444   0.264   0.251   0.388   0.189   0.175
302   I         0.479   0.629   0.436   0.270   0.499   0.179   0.388   0.624   0.304
303   D        -0.640  -0.633  -0.641  -0.585  -0.571  -0.596  -0.660  -0.643  -0.640
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   I        -0.640  -0.700  -0.675  -0.664  -0.760  -0.681  -0.660  -0.722  -0.683
307   E        -1.453  -1.398  -1.381  -1.235  -1.143  -1.112  -1.184  -1.104  -1.069
308   M        -1.453  -1.398  -1.381  -1.288  -1.204  -1.165  -1.184  -1.104  -1.069
309   L         0.479   0.505   0.404   0.272   0.321   0.182   0.388   0.427   0.250
310   K        -1.453  -1.398  -1.381  -1.323  -1.248  -1.201  -1.184  -1.104  -1.069
311   S        -0.640  -0.700  -0.675  -0.698  -0.815  -0.768  -0.660  -0.722  -0.683
312   F         0.479   0.362   0.360   0.554   0.354   0.354   0.388   0.189   0.175
313   N         1.798   1.846   1.877   1.762   1.827   1.894   1.960   2.025   2.075
314   V        -0.640  -0.700  -0.675  -0.654  -0.757  -0.719  -0.660  -0.722  -0.683
315   E        -0.640  -0.700  -0.675  -0.515  -0.599  -0.550  -0.660  -0.722  -0.683
316   K        -0.640  -0.641  -0.643  -0.603  -0.618  -0.606  -0.660  -0.653  -0.643
317   D         0.479   0.362   0.360   0.661   0.500   0.483   0.388   0.189   0.175
318   A        -1.453  -1.398  -1.381  -1.247  -1.165  -1.124  -1.184  -1.104  -1.069
319   I         0.173   0.233   0.264  -0.359  -0.284  -0.215  -0.136  -0.036   0.007
320   E        -0.640  -0.545  -0.605  -0.510  -0.369  -0.442  -0.660  -0.523  -0.594
321   L        -1.453  -1.398  -1.381  -1.465  -1.358  -1.343  -1.184  -1.104  -1.069
322   L        -0.640  -0.700  -0.675  -0.970  -1.056  -1.007  -0.660  -0.722  -0.683
323   I        -0.640  -0.641  -0.643  -0.956  -0.952  -0.947  -0.660  -0.653  -0.643
324   P         0.479   0.362   0.360   0.537   0.363   0.341   0.388   0.189   0.175
325   R        -1.453  -1.398  -1.381  -1.173  -1.036  -1.050  -1.184  -1.104  -1.069
326   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   D        -0.778  -0.748  -0.705  -0.737  -0.657  -0.612  -0.835  -0.779  -0.720
332   L        -1.453  -1.398  -1.381  -1.333  -1.181  -1.210  -1.184  -1.104  -1.069
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04299
Output conservation file - output/Q04299
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
