1     M         1.447   1.467   1.485   1.693   1.729   1.754   1.536   1.561   1.587
2     T        -1.575  -1.532  -1.513  -1.508  -1.480  -1.406  -1.267  -1.210  -1.173
3     E        -0.820  -0.843  -0.838  -0.861  -0.903  -0.876  -0.800  -0.824  -0.804
4     P        -0.820  -0.728  -0.811  -0.664  -0.527  -0.644  -0.800  -0.676  -0.771
5     Q         0.059   0.033   0.022  -0.013  -0.058  -0.086  -0.125  -0.168  -0.192
6     G         1.447   1.467   1.485   1.613   1.643   1.675   1.536   1.561   1.587
7     P         0.221   0.088   0.095   0.370   0.138   0.154   0.135  -0.078  -0.071
8     L         0.221   0.088   0.095   0.109  -0.085  -0.069   0.135  -0.078  -0.071
9     D        -0.820  -0.870  -0.856  -0.739  -0.834  -0.786  -0.800  -0.854  -0.825
10    T        -0.820  -0.870  -0.856  -0.827  -0.919  -0.908  -0.800  -0.854  -0.825
11    I        -0.820  -0.870  -0.856  -0.807  -0.882  -0.887  -0.800  -0.854  -0.825
12    P         1.447   1.467   1.485   1.586   1.617   1.648   1.536   1.561   1.587
13    K        -0.820  -0.870  -0.856  -0.997  -1.060  -1.053  -0.800  -0.854  -0.825
14    V        -1.575  -1.532  -1.513  -1.335  -1.258  -1.235  -1.267  -1.210  -1.173
15    N        -0.820  -0.870  -0.856  -0.829  -0.903  -0.878  -0.800  -0.854  -0.825
16    Y         0.221   0.088   0.095   0.427   0.207   0.217   0.135  -0.078  -0.071
17    P        -0.820  -0.870  -0.856  -0.702  -0.807  -0.777  -0.800  -0.854  -0.825
18    P         0.221   0.088   0.095   0.446   0.250   0.264   0.135  -0.078  -0.071
19    I        -0.820  -0.693  -0.812  -0.863  -0.655  -0.854  -0.800  -0.632  -0.772
20    L        -0.820  -0.870  -0.856  -0.874  -0.911  -0.895  -0.800  -0.854  -0.825
21    T         0.221   0.088   0.095   0.307   0.092   0.097   0.135  -0.078  -0.071
22    I        -1.575  -1.532  -1.513  -1.456  -1.372  -1.355  -1.267  -1.210  -1.173
23    A         0.221   0.088   0.095   0.348   0.104   0.133   0.135  -0.078  -0.071
24    N         0.221   0.268   0.120   0.196   0.269   0.034   0.135   0.208  -0.031
25    Y         0.221   0.088   0.095   0.409   0.181   0.190   0.135  -0.078  -0.071
26    F        -1.575  -1.532  -1.513  -1.189  -1.129  -1.091  -1.267  -1.210  -1.173
27    S         0.221   0.088   0.095   0.262   0.043   0.065   0.135  -0.078  -0.071
28    T         0.221   0.088   0.095   0.339   0.129   0.144   0.135  -0.078  -0.071
29    K         0.221   0.088   0.095   0.158  -0.028  -0.015   0.135  -0.078  -0.071
30    Q         1.447   1.467   1.485   1.462   1.500   1.525   1.536   1.561   1.587
31    M         0.059   0.105   0.039   0.102   0.190   0.029  -0.125  -0.049  -0.163
32    I         1.447   1.467   1.485   1.511   1.546   1.574   1.536   1.561   1.587
33    D         0.059   0.105   0.039  -0.041   0.039  -0.088  -0.125  -0.049  -0.163
34    Q         0.059   0.105   0.039  -0.064   0.022  -0.115  -0.125  -0.049  -0.163
35    V         1.447   1.467   1.485   1.506   1.535   1.569   1.536   1.561   1.587
36    I         0.059   0.095   0.041  -0.187  -0.130  -0.208  -0.125  -0.066  -0.161
37    S         0.059   0.033   0.022  -0.016  -0.069  -0.098  -0.125  -0.168  -0.192
38    E         1.447   1.467   1.485   1.351   1.384   1.415   1.536   1.561   1.587
39    D         1.447   1.467   1.485   1.462   1.494   1.525   1.536   1.561   1.587
40    Q         0.059   0.105   0.039   0.027   0.107  -0.006  -0.125  -0.049  -0.163
41    D         0.059   0.095   0.041  -0.116  -0.057  -0.148  -0.125  -0.066  -0.161
42    Y         1.447   1.467   1.485   1.619   1.653   1.680   1.536   1.561   1.587
43    V         0.221   0.088   0.095   0.326   0.110   0.131   0.135  -0.078  -0.071
44    T        -0.820  -0.870  -0.856  -0.558  -0.611  -0.585  -0.800  -0.854  -0.825
45    W         0.221   0.088   0.095   0.561   0.337   0.349   0.135  -0.078  -0.071
46    K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
47    L         0.221   0.088   0.095   0.109  -0.085  -0.069   0.135  -0.078  -0.071
48    Q        -0.820  -0.728  -0.811  -0.831  -0.687  -0.812  -0.800  -0.676  -0.771
49    N        -0.820  -0.843  -0.838  -0.829  -0.856  -0.852  -0.800  -0.824  -0.804
50    L        -0.820  -0.870  -0.856  -0.898  -0.962  -0.925  -0.800  -0.854  -0.825
51    R         0.221   0.088   0.095   0.299   0.061   0.088   0.135  -0.078  -0.071
52    T        -0.820  -0.870  -0.856  -0.783  -0.847  -0.854  -0.800  -0.854  -0.825
53    G        -0.064  -0.031  -0.005  -0.056  -0.018   0.039  -0.333  -0.276  -0.238
54    G         0.221   0.088   0.095   0.430   0.208   0.228   0.135  -0.078  -0.071
55    T        -0.820  -0.839  -0.837  -0.882  -0.936  -0.911  -0.800  -0.820  -0.803
56    -        -0.948  -0.922  -0.891  -0.802  -0.758  -0.709  -0.956  -0.913  -0.866
57    -         0.059   0.117   0.065  -0.025   0.073  -0.029  -0.125  -0.030  -0.120
58    -         0.059   0.117   0.065   0.113   0.211   0.115  -0.125  -0.030  -0.120
59    -        -0.948  -0.922  -0.891  -0.832  -0.814  -0.739  -0.956  -0.913  -0.866
60    -        -0.948  -0.922  -0.891  -1.122  -1.082  -1.025  -0.956  -0.913  -0.866
61    -         0.059   0.117   0.065  -0.144  -0.042  -0.131  -0.125  -0.030  -0.120
62    -         0.059   0.119   0.065  -0.231  -0.120  -0.230  -0.125  -0.028  -0.121
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    S        -0.948  -0.930  -0.891  -1.013  -0.986  -0.917  -0.956  -0.922  -0.866
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    I         0.059   0.095   0.041   0.050   0.107   0.012  -0.125  -0.066  -0.161
68    N        -0.948  -0.930  -0.891  -1.033  -1.012  -0.938  -0.956  -0.922  -0.866
69    N         0.059   0.095   0.041   0.187   0.251   0.128  -0.125  -0.066  -0.161
70    Q        -0.948  -0.930  -0.891  -0.764  -0.730  -0.672  -0.956  -0.922  -0.866
71    L        -0.948  -0.930  -0.891  -1.196  -1.155  -1.098  -0.956  -0.922  -0.866
72    N         0.059   0.033   0.022  -0.057  -0.102  -0.121  -0.125  -0.168  -0.192
73    K        -0.948  -0.930  -0.891  -0.932  -0.890  -0.838  -0.956  -0.922  -0.866
74    Y        -0.948  -0.930  -0.891  -0.992  -0.969  -0.897  -0.956  -0.922  -0.866
75    P        -0.948  -0.930  -0.891  -0.662  -0.623  -0.571  -0.956  -0.922  -0.866
76    K         0.059   0.095   0.041   0.138   0.204   0.071  -0.125  -0.066  -0.161
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
87    Y        -0.820  -0.839  -0.837  -0.915  -0.966  -0.928  -0.800  -0.820  -0.803
88    Q         0.221   0.322   0.146   0.201   0.359   0.084   0.135   0.291   0.012
89    K        -1.575  -1.532  -1.513  -1.242  -1.138  -1.144  -1.267  -1.210  -1.173
90    T        -0.820  -0.693  -0.812  -0.896  -0.679  -0.884  -0.800  -0.632  -0.772
91    R        -0.820  -0.733  -0.811  -0.809  -0.671  -0.801  -0.800  -0.681  -0.771
92    I        -1.575  -1.532  -1.513  -1.318  -1.263  -1.219  -1.267  -1.210  -1.173
93    N        -1.575  -1.532  -1.513  -1.661  -1.587  -1.557  -1.267  -1.210  -1.173
94    Q        -0.820  -0.839  -0.837  -0.988  -1.031  -1.013  -0.800  -0.820  -0.803
95    Q        -1.575  -1.532  -1.513  -1.592  -1.527  -1.489  -1.267  -1.210  -1.173
96    D        -0.820  -0.733  -0.811  -0.733  -0.598  -0.713  -0.800  -0.681  -0.771
97    P        -0.820  -0.870  -0.856  -0.781  -0.907  -0.872  -0.800  -0.854  -0.825
98    D        -1.575  -1.532  -1.513  -1.439  -1.391  -1.338  -1.267  -1.210  -1.173
99    S        -1.575  -1.532  -1.513  -1.576  -1.528  -1.474  -1.267  -1.210  -1.173
100   I        -0.820  -0.870  -0.856  -0.825  -0.905  -0.909  -0.800  -0.854  -0.825
101   N        -0.820  -0.843  -0.838  -0.859  -0.904  -0.887  -0.800  -0.824  -0.804
102   K        -0.820  -0.693  -0.812  -0.761  -0.563  -0.750  -0.800  -0.632  -0.772
103   V         0.059   0.033   0.022   0.050   0.000  -0.020  -0.125  -0.168  -0.192
104   P         1.447   1.467   1.485   1.598   1.634   1.659   1.536   1.561   1.587
105   E         0.059   0.095   0.041   0.062   0.129   0.006  -0.125  -0.066  -0.161
106   N         1.447   1.467   1.485   1.401   1.434   1.465   1.536   1.561   1.587
107   L         0.059   0.033   0.022  -0.189  -0.233  -0.239  -0.125  -0.168  -0.192
108   I        -0.948  -0.930  -0.891  -0.935  -0.904  -0.841  -0.956  -0.922  -0.866
109   F         1.447   1.467   1.485   1.641   1.674   1.702   1.536   1.561   1.587
110   P        -0.948  -0.930  -0.891  -0.821  -0.786  -0.728  -0.956  -0.922  -0.866
111   Q        -0.820  -0.870  -0.856  -0.781  -0.870  -0.837  -0.800  -0.854  -0.825
112   D         1.447   1.467   1.485   1.463   1.496   1.526   1.536   1.561   1.587
113   I        -0.820  -0.843  -0.838  -0.749  -0.756  -0.787  -0.800  -0.824  -0.804
114   L        -0.820  -0.839  -0.837  -0.677  -0.693  -0.721  -0.800  -0.820  -0.803
115   Q        -0.820  -0.839  -0.837  -0.882  -0.905  -0.898  -0.800  -0.820  -0.803
116   Q        -1.575  -1.532  -1.513  -1.502  -1.420  -1.401  -1.267  -1.210  -1.173
117   Q        -1.575  -1.532  -1.513  -1.598  -1.503  -1.495  -1.267  -1.210  -1.173
118   T        -0.820  -0.693  -0.812  -0.625  -0.426  -0.605  -0.800  -0.632  -0.772
119   Q        -0.820  -0.839  -0.837  -0.940  -0.974  -0.957  -0.800  -0.820  -0.803
120   N        -0.820  -0.728  -0.811  -0.967  -0.817  -0.948  -0.800  -0.676  -0.771
121   S        -1.575  -1.532  -1.513  -1.661  -1.569  -1.557  -1.267  -1.210  -1.173
122   N        -1.575  -1.532  -1.513  -1.418  -1.350  -1.318  -1.267  -1.210  -1.173
123   Y        -1.575  -1.532  -1.513  -1.369  -1.290  -1.269  -1.267  -1.210  -1.173
124   E        -1.575  -1.532  -1.513  -1.587  -1.531  -1.484  -1.267  -1.210  -1.173
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   D         0.059  -0.012   0.022   0.044  -0.075  -0.017  -0.125  -0.244  -0.192
127   T        -0.948  -0.908  -0.891  -0.990  -0.888  -0.895  -0.956  -0.896  -0.866
128   N        -0.948  -0.908  -0.891  -1.128  -1.080  -1.032  -0.956  -0.896  -0.866
129   T         0.059   0.141   0.065  -0.066   0.094  -0.069  -0.125   0.009  -0.120
130   N        -0.820  -0.839  -0.837  -0.787  -0.837  -0.824  -0.800  -0.820  -0.803
131   E         0.221   0.088   0.095   0.140  -0.074  -0.058   0.135  -0.078  -0.071
132   D        -1.575  -1.532  -1.513  -1.542  -1.495  -1.440  -1.267  -1.210  -1.173
133   E        -1.575  -1.532  -1.513  -1.379  -1.315  -1.279  -1.267  -1.210  -1.173
134   N        -0.820  -0.733  -0.811  -0.904  -0.756  -0.892  -0.800  -0.681  -0.771
135   E        -0.820  -0.733  -0.811  -0.829  -0.702  -0.802  -0.800  -0.681  -0.771
136   K        -0.820  -0.733  -0.811  -0.942  -0.803  -0.921  -0.800  -0.681  -0.771
137   L         0.221   0.317   0.143   0.098   0.252  -0.011   0.135   0.282   0.007
138   A        -1.575  -1.532  -1.513  -1.436  -1.384  -1.335  -1.267  -1.210  -1.173
139   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   F         0.059  -0.012   0.022   0.157   0.019   0.073  -0.125  -0.244  -0.192
144   K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
145   L         0.221   0.088   0.095   0.131  -0.046  -0.038   0.135  -0.078  -0.071
146   L         0.221   0.268   0.120   0.134   0.214   0.001   0.135   0.208  -0.031
147   V        -0.820  -0.870  -0.856  -0.747  -0.860  -0.807  -0.800  -0.854  -0.825
148   T        -0.820  -0.870  -0.856  -0.813  -0.924  -0.891  -0.800  -0.854  -0.825
149   N        -0.820  -0.870  -0.856  -0.751  -0.842  -0.785  -0.800  -0.854  -0.825
150   L         0.221   0.088   0.095   0.134  -0.044  -0.034   0.135  -0.078  -0.071
151   D         1.447   1.467   1.485   1.463   1.496   1.526   1.536   1.561   1.587
152   K        -0.820  -0.728  -0.811  -0.976  -0.819  -0.961  -0.800  -0.676  -0.771
153   D        -0.064  -0.031  -0.005  -0.324  -0.276  -0.228  -0.333  -0.276  -0.238
154   Q         1.447   1.467   1.485   1.468   1.506   1.531   1.536   1.561   1.587
155   T        -0.064  -0.031  -0.005  -0.031   0.048   0.079  -0.333  -0.276  -0.238
156   N         0.221   0.088   0.095   0.201  -0.009  -0.001   0.135  -0.078  -0.071
157   R         1.447   1.467   1.485   1.513   1.533   1.576   1.536   1.561   1.587
158   F        -0.064  -0.031  -0.005   0.005   0.064   0.102  -0.333  -0.276  -0.238
159   E         1.447   1.467   1.485   1.346   1.377   1.411   1.536   1.561   1.587
160   V         1.447   1.467   1.485   1.504   1.535   1.567   1.536   1.561   1.587
161   F         1.447   1.467   1.485   1.636   1.668   1.697   1.536   1.561   1.587
162   H        -0.820  -0.870  -0.856  -0.637  -0.740  -0.732  -0.800  -0.854  -0.825
163   R         1.447   1.467   1.485   1.513   1.533   1.576   1.536   1.561   1.587
164   T         0.221   0.088   0.095   0.339   0.129   0.144   0.135  -0.078  -0.071
165   S        -0.820  -0.843  -0.838  -0.795  -0.868  -0.822  -0.800  -0.824  -0.804
166   L         1.447   1.467   1.485   1.280   1.323   1.345   1.536   1.561   1.587
167   N        -0.820  -0.733  -0.811  -0.815  -0.686  -0.795  -0.800  -0.681  -0.771
168   K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
169   T         0.221   0.268   0.120   0.289   0.371   0.115   0.135   0.208  -0.031
170   Q         0.221   0.088   0.095   0.240   0.022   0.025   0.135  -0.078  -0.071
171   V         0.221   0.268   0.120   0.316   0.390   0.157   0.135   0.208  -0.031
172   K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
173   K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
174   L         0.221   0.268   0.120   0.098   0.183  -0.047   0.135   0.208  -0.031
175   A         0.221   0.268   0.120   0.348   0.403   0.177   0.135   0.208  -0.031
176   S        -1.575  -1.532  -1.513  -1.428  -1.379  -1.328  -1.267  -1.210  -1.173
177   T        -0.820  -0.870  -0.856  -0.739  -0.824  -0.802  -0.800  -0.854  -0.825
178   V         0.221   0.088   0.095   0.316   0.107   0.116   0.135  -0.078  -0.071
179   A        -1.575  -1.532  -1.513  -1.497  -1.468  -1.396  -1.267  -1.210  -1.173
180   N         1.447   1.467   1.485   1.407   1.443   1.471   1.536   1.561   1.587
181   Q         1.447   1.467   1.485   1.468   1.506   1.531   1.536   1.561   1.587
182   T        -0.064  -0.040  -0.011  -0.204  -0.173  -0.116  -0.333  -0.291  -0.248
183   I        -0.064  -0.031  -0.005  -0.158  -0.097  -0.059  -0.333  -0.276  -0.238
184   S        -1.575  -1.532  -1.513  -1.456  -1.386  -1.355  -1.267  -1.210  -1.173
185   E        -0.820  -0.870  -0.856  -0.878  -0.937  -0.919  -0.800  -0.854  -0.825
186   N         1.447   1.467   1.485   1.407   1.443   1.471   1.536   1.561   1.587
187   I         0.221   0.088   0.095   0.333   0.125   0.128   0.135  -0.078  -0.071
188   R        -0.820  -0.870  -0.856  -0.743  -0.837  -0.805  -0.800  -0.854  -0.825
189   V        -0.820  -0.870  -0.856  -0.819  -0.890  -0.894  -0.800  -0.854  -0.825
190   F        -0.820  -0.870  -0.856  -0.716  -0.807  -0.807  -0.800  -0.854  -0.825
191   L         0.221   0.088   0.095   0.098  -0.088  -0.085   0.135  -0.078  -0.071
192   Q        -0.820  -0.870  -0.856  -0.741  -0.836  -0.790  -0.800  -0.854  -0.825
193   A        -0.064  -0.031  -0.005  -0.056  -0.007   0.046  -0.333  -0.276  -0.238
194   V        -0.820  -0.843  -0.838  -0.667  -0.694  -0.687  -0.800  -0.824  -0.804
195   G         0.221   0.088   0.095   0.396   0.162   0.178   0.135  -0.078  -0.071
196   K         1.447   1.467   1.485   1.313   1.353   1.378   1.536   1.561   1.587
197   I         0.221   0.088   0.095   0.333   0.125   0.128   0.135  -0.078  -0.071
198   Y         0.221   0.322   0.146   0.471   0.621   0.359   0.135   0.291   0.012
199   A        -0.064  -0.031  -0.005  -0.134  -0.093  -0.038  -0.333  -0.276  -0.238
200   G         1.447   1.467   1.485   1.613   1.643   1.675   1.536   1.561   1.587
201   E         1.447   1.467   1.485   1.346   1.377   1.411   1.536   1.561   1.587
202   I         1.447   1.467   1.485   1.532   1.574   1.594   1.536   1.561   1.587
203   I        -0.064  -0.031  -0.005  -0.158  -0.097  -0.059  -0.333  -0.276  -0.238
204   E         1.447   1.467   1.485   1.346   1.377   1.411   1.536   1.561   1.587
205   L        -0.064  -0.040  -0.011  -0.487  -0.433  -0.394  -0.333  -0.292  -0.249
206   A         1.447   1.467   1.485   1.564   1.580   1.626   1.536   1.561   1.587
207   M        -0.820  -0.870  -0.856  -0.662  -0.760  -0.759  -0.800  -0.854  -0.825
208   I        -1.575  -1.532  -1.513  -1.619  -1.560  -1.516  -1.267  -1.210  -1.173
209   V         0.221   0.322   0.146   0.333   0.495   0.214   0.135   0.291   0.012
210   K         0.221   0.088   0.095   0.109  -0.092  -0.086   0.135  -0.078  -0.071
211   N        -0.820  -0.839  -0.837  -0.934  -0.965  -0.957  -0.800  -0.820  -0.803
212   K         0.221   0.088   0.095   0.109  -0.092  -0.086   0.135  -0.078  -0.071
213   W         1.447   1.467   1.485   1.751   1.785   1.810   1.536   1.561   1.587
214   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
215   T         0.059   0.095   0.041  -0.187  -0.128  -0.208  -0.125  -0.066  -0.161
216   S         0.059   0.033   0.022   0.087   0.045   0.031  -0.125  -0.168  -0.192
217   Q         0.059   0.095   0.041  -0.211  -0.151  -0.237  -0.125  -0.066  -0.161
218   M         0.059   0.033   0.022   0.213   0.160   0.128  -0.125  -0.168  -0.192
219   C        -0.948  -0.930  -0.891  -0.638  -0.622  -0.547  -0.956  -0.922  -0.866
220   I        -0.948  -0.930  -0.891  -0.975  -0.952  -0.881  -0.956  -0.922  -0.866
221   E         0.059   0.033   0.022  -0.197  -0.254  -0.282  -0.125  -0.168  -0.192
222   F         1.447   1.467   1.485   1.641   1.674   1.702   1.536   1.561   1.587
223   D         0.059   0.033   0.022   0.102   0.066   0.059  -0.125  -0.168  -0.192
224   K        -0.948  -0.930  -0.891  -1.146  -1.123  -1.049  -0.956  -0.922  -0.866
225   R         0.059   0.105   0.039  -0.011   0.072  -0.072  -0.125  -0.049  -0.163
226   T        -0.948  -0.930  -0.891  -1.171  -1.147  -1.073  -0.956  -0.922  -0.866
227   K        -0.948  -0.930  -0.891  -1.146  -1.104  -1.049  -0.956  -0.922  -0.866
228   I         0.059   0.105   0.039   0.055   0.136   0.015  -0.125  -0.049  -0.163
229   G         0.059   0.105   0.039   0.204   0.280   0.166  -0.125  -0.049  -0.163
230   Y        -0.948  -0.930  -0.891  -0.764  -0.744  -0.672  -0.956  -0.922  -0.866
231   K        -0.948  -0.930  -0.891  -1.057  -1.028  -0.962  -0.956  -0.922  -0.866
232   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
233   K         1.447   1.467   1.485   1.289   1.319   1.354   1.536   1.561   1.587
234   K         1.447   1.467   1.485   1.289   1.319   1.354   1.536   1.561   1.587
235   Y        -0.948  -0.930  -0.891  -0.899  -0.851  -0.805  -0.956  -0.922  -0.866
236   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
237   K         1.447   1.467   1.485   1.289   1.319   1.354   1.536   1.561   1.587
238   K         1.447   1.467   1.485   1.289   1.319   1.354   1.536   1.561   1.587
239   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
240   T         1.447   1.467   1.485   1.511   1.549   1.574   1.536   1.561   1.587
241   F        -0.948  -0.930  -0.891  -0.962  -0.927  -0.867  -0.956  -0.922  -0.866
242   S        -0.948  -0.930  -0.891  -0.992  -0.984  -0.897  -0.956  -0.922  -0.866
243   I         0.059   0.095   0.041   0.050   0.107   0.012  -0.125  -0.066  -0.161
244   I        -0.948  -0.930  -0.891  -1.061  -1.038  -0.965  -0.956  -0.922  -0.866
245   E        -0.948  -0.930  -0.891  -1.146  -1.103  -1.049  -0.956  -0.922  -0.866
246   N         0.059   0.033   0.022  -0.057  -0.102  -0.121  -0.125  -0.168  -0.192
247   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   S         1.447   1.467   1.485   1.489   1.521   1.552   1.536   1.561   1.587
273   V         1.447   1.467   1.485   1.506   1.535   1.569   1.536   1.561   1.587
274   P        -0.948  -0.930  -0.891  -0.939  -0.907  -0.844  -0.956  -0.922  -0.866
275   E         1.447   1.467   1.485   1.351   1.384   1.415   1.536   1.561   1.587
276   D        -0.948  -0.930  -0.891  -1.075  -1.041  -0.979  -0.956  -0.922  -0.866
277   E         1.447   1.467   1.485   1.351   1.384   1.415   1.536   1.561   1.587
278   P         0.059   0.105   0.039   0.062   0.148   0.003  -0.125  -0.049  -0.163
279   D         0.059   0.033   0.022  -0.064  -0.119  -0.150  -0.125  -0.168  -0.192
280   F        -0.948  -0.930  -0.891  -0.866  -0.840  -0.773  -0.956  -0.922  -0.866
281   Y         0.059   0.033   0.022   0.199   0.156   0.131  -0.125  -0.168  -0.192
282   F        -0.948  -0.930  -0.891  -1.040  -1.008  -0.945  -0.956  -0.922  -0.866
283   D         0.059   0.033   0.022   0.010  -0.034  -0.057  -0.125  -0.168  -0.192
284   D         1.447   1.467   1.485   1.462   1.494   1.525   1.536   1.561   1.587
285   E         0.059   0.033   0.022  -0.116  -0.162  -0.179  -0.125  -0.168  -0.192
286   E         0.059   0.105   0.039  -0.051   0.022  -0.073  -0.125  -0.049  -0.163
287   V        -0.948  -0.930  -0.891  -0.896  -0.860  -0.802  -0.956  -0.922  -0.866
288   D        -0.948  -0.930  -0.891  -0.996  -0.976  -0.901  -0.956  -0.922  -0.866
289   K        -0.948  -0.930  -0.891  -0.955  -0.926  -0.861  -0.956  -0.922  -0.866
290   R         0.059   0.095   0.041  -0.132  -0.078  -0.152  -0.125  -0.066  -0.161
291   E        -0.948  -0.930  -0.891  -1.085  -1.037  -0.989  -0.956  -0.922  -0.866
292   T        -0.948  -0.930  -0.891  -0.824  -0.780  -0.731  -0.956  -0.922  -0.866
293   T        -0.948  -0.930  -0.891  -1.099  -1.076  -1.003  -0.956  -0.922  -0.866
294   L        -0.948  -0.930  -0.891  -1.124  -1.083  -1.027  -0.956  -0.922  -0.866
295   G        -0.948  -0.930  -0.891  -0.879  -0.856  -0.786  -0.956  -0.922  -0.866
296   N         1.447   1.467   1.485   1.401   1.434   1.465   1.536   1.561   1.587
297   S         0.059   0.033   0.022  -0.016  -0.069  -0.098  -0.125  -0.168  -0.192
298   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
299   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
300   Q         0.059   0.105   0.039   0.027   0.107  -0.006  -0.125  -0.049  -0.163
301   S         1.447   1.467   1.485   1.489   1.521   1.552   1.536   1.561   1.587
302   K         0.059   0.095   0.041  -0.093  -0.025  -0.146  -0.125  -0.066  -0.161
303   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   H        -0.948  -0.930  -0.891  -0.972  -0.947  -0.877  -0.956  -0.922  -0.866
310   N         1.447   1.467   1.485   1.401   1.434   1.465   1.536   1.561   1.587
311   S        -0.948  -0.930  -0.891  -0.949  -0.919  -0.854  -0.956  -0.922  -0.866
312   Q        -0.948  -0.930  -0.891  -0.996  -0.973  -0.901  -0.956  -0.922  -0.866
313   D        -0.948  -0.930  -0.891  -1.075  -1.041  -0.979  -0.956  -0.922  -0.866
314   L        -0.948  -0.930  -0.891  -1.096  -1.062  -0.999  -0.956  -0.922  -0.866
315   K         0.059   0.095   0.041  -0.011   0.052  -0.069  -0.125  -0.066  -0.161
316   L         0.059   0.033   0.022  -0.294  -0.349  -0.371  -0.125  -0.168  -0.192
317   Q        -0.948  -0.930  -0.891  -0.869  -0.831  -0.776  -0.956  -0.922  -0.866
318   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
319   I         1.447   1.467   1.485   1.511   1.546   1.574   1.536   1.561   1.587
320   E        -0.948  -0.930  -0.891  -1.185  -1.166  -1.088  -0.956  -0.922  -0.866
321   Q         0.059   0.105   0.039   0.102   0.177   0.082  -0.125  -0.049  -0.163
322   Y         1.447   1.467   1.485   1.619   1.653   1.680   1.536   1.561   1.587
323   N         1.447   1.467   1.485   1.401   1.434   1.465   1.536   1.561   1.587
324   K        -0.948  -0.930  -0.891  -1.171  -1.129  -1.073  -0.956  -0.922  -0.866
325   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
326   V         1.447   1.467   1.485   1.506   1.535   1.569   1.536   1.561   1.587
327   L        -0.948  -0.930  -0.891  -1.002  -0.961  -0.907  -0.956  -0.922  -0.866
328   Q         0.059   0.033   0.022  -0.093  -0.147  -0.186  -0.125  -0.168  -0.192
329   F         1.447   1.467   1.485   1.641   1.674   1.702   1.536   1.561   1.587
330   N         1.447   1.467   1.485   1.401   1.434   1.465   1.536   1.561   1.587
331   K         0.059   0.095   0.041  -0.197  -0.136  -0.245  -0.125  -0.066  -0.161
332   L         1.447   1.467   1.485   1.249   1.281   1.315   1.536   1.561   1.587
333   D         1.447   1.467   1.485   1.462   1.494   1.525   1.536   1.561   1.587
334   V         1.447   1.467   1.485   1.506   1.535   1.569   1.536   1.561   1.587
335   S         1.447   1.467   1.485   1.489   1.521   1.552   1.536   1.561   1.587
336   I         0.059   0.095   0.041   0.050   0.107   0.012  -0.125  -0.066  -0.161
337   E         1.447   1.467   1.485   1.351   1.384   1.415   1.536   1.561   1.587
338   K         1.447   1.467   1.485   1.289   1.319   1.354   1.536   1.561   1.587
339   Y         0.221   0.088   0.095   0.459   0.254   0.262   0.135  -0.078  -0.071
340   N        -0.820  -0.870  -0.856  -0.921  -0.997  -0.989  -0.800  -0.854  -0.825
341   N        -1.575  -1.532  -1.513  -1.513  -1.429  -1.411  -1.267  -1.210  -1.173
342   S         0.221   0.088   0.095   0.293   0.082   0.110   0.135  -0.078  -0.071
343   P         1.447   1.467   1.485   1.586   1.617   1.648   1.536   1.561   1.587
344   L         1.447   1.467   1.485   1.280   1.323   1.345   1.536   1.561   1.587
345   L         0.221   0.088   0.095   0.072  -0.135  -0.123   0.135  -0.078  -0.071
346   P         1.447   1.467   1.485   1.586   1.617   1.648   1.536   1.561   1.587
347   E         0.221   0.088   0.095   0.140  -0.074  -0.058   0.135  -0.078  -0.071
348   H         1.447   1.467   1.485   1.707   1.740   1.767   1.536   1.561   1.587
349   I        -0.820  -0.870  -0.856  -0.807  -0.915  -0.887  -0.800  -0.854  -0.825
350   R         0.221   0.268   0.120   0.381   0.439   0.243   0.135   0.208  -0.031
351   E         1.447   1.467   1.485   1.346   1.377   1.411   1.536   1.561   1.587
352   A         1.447   1.467   1.485   1.564   1.580   1.626   1.536   1.561   1.587
353   W         0.221   0.088   0.095   0.581   0.373   0.377   0.135  -0.078  -0.071
354   R         1.447   1.467   1.485   1.513   1.533   1.576   1.536   1.561   1.587
355   L         1.447   1.467   1.485   1.280   1.323   1.345   1.536   1.561   1.587
356   Y        -0.820  -0.843  -0.838  -0.567  -0.638  -0.597  -0.800  -0.824  -0.804
357   R         1.447   1.467   1.485   1.513   1.533   1.576   1.536   1.561   1.587
358   L        -0.820  -0.870  -0.856  -0.934  -0.990  -0.967  -0.800  -0.854  -0.825
359   Q        -0.820  -0.870  -0.856  -0.878  -0.968  -0.955  -0.800  -0.854  -0.825
360   S        -0.820  -0.870  -0.856  -0.817  -0.912  -0.877  -0.800  -0.854  -0.825
361   D        -0.820  -0.843  -0.838  -0.835  -0.877  -0.871  -0.800  -0.824  -0.804
362   T         0.221   0.088   0.095   0.249   0.016   0.012   0.135  -0.078  -0.071
363   L        -0.820  -0.843  -0.838  -0.861  -0.861  -0.862  -0.800  -0.824  -0.804
364   P         1.447   1.467   1.485   1.586   1.617   1.648   1.536   1.561   1.587
365   N        -0.948  -0.930  -0.891  -0.959  -0.930  -0.864  -0.956  -0.922  -0.866
366   A         0.059   0.033   0.022   0.199   0.157   0.133  -0.125  -0.168  -0.192
367   Y        -0.948  -0.930  -0.891  -0.909  -0.881  -0.815  -0.956  -0.922  -0.866
368   W         0.059   0.033   0.022   0.319   0.273   0.242  -0.125  -0.168  -0.192
369   R         1.447   1.467   1.485   1.549   1.581   1.611   1.536   1.561   1.587
370   T         1.447   1.467   1.485   1.511   1.549   1.574   1.536   1.561   1.587
371   Q         1.447   1.467   1.485   1.468   1.506   1.531   1.536   1.561   1.587
372   G         0.221   0.088   0.095   0.396   0.162   0.178   0.135  -0.078  -0.071
373   E        -0.820  -0.843  -0.838  -0.890  -0.936  -0.909  -0.800  -0.824  -0.804
374   G        -0.820  -0.870  -0.856  -0.534  -0.608  -0.582  -0.800  -0.854  -0.825
375   Q        -0.820  -0.839  -0.837  -0.835  -0.864  -0.857  -0.800  -0.820  -0.803
376   G         0.221   0.088   0.095   0.396   0.162   0.178   0.135  -0.078  -0.071
377   S        -1.575  -1.532  -1.513  -1.472  -1.354  -1.370  -1.267  -1.210  -1.173
378   M         0.221   0.088   0.095   0.420   0.178   0.173   0.135  -0.078  -0.071
379   F         1.447   1.467   1.485   1.636   1.668   1.697   1.536   1.561   1.587
380   R         1.447   1.467   1.485   1.513   1.533   1.576   1.536   1.561   1.587
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04226
Output conservation file - output/Q04226
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
