1     M         2.244   2.356   2.422   2.578   2.756   2.893   2.612   2.796   2.936
2     S        -0.129  -0.303  -0.274  -0.127  -0.459  -0.417  -0.174  -0.415  -0.377
3     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    M        -0.500  -0.439  -0.383  -0.493  -0.417  -0.300  -0.705  -0.609  -0.533
27    V        -0.353  -0.324  -0.327  -0.560  -0.529  -0.549  -0.498  -0.457  -0.454
28    C        -1.775  -1.708  -1.687  -1.621  -1.522  -1.474  -1.368  -1.272  -1.226
29    T        -0.391  -0.296  -0.304  -0.525  -0.382  -0.376  -0.572  -0.439  -0.433
30    L         0.994   0.892   0.878   1.033   0.883   0.877   1.020   0.823   0.781
31    N         0.994   0.892   0.878   1.048   0.893   0.858   1.020   0.823   0.781
32    K        -1.775  -1.708  -1.687  -1.638  -1.519  -1.491  -1.368  -1.272  -1.226
33    T         0.994   0.892   0.878   1.156   0.992   0.965   1.020   0.823   0.781
34    T        -1.775  -1.708  -1.687  -1.556  -1.488  -1.406  -1.368  -1.272  -1.226
35    D         2.244   2.356   2.422   2.268   2.455   2.571   2.612   2.796   2.936
36    A        -1.083  -1.029  -1.031  -1.174  -1.073  -1.099  -0.970  -0.887  -0.870
37    R        -1.775  -1.708  -1.687  -1.664  -1.544  -1.519  -1.368  -1.272  -1.226
38    R         0.563   0.744   0.750   0.288   0.579   0.587   0.224   0.543   0.530
39    A         0.994   0.944   0.898   0.991   0.907   0.834   1.020   0.917   0.819
40    A        -0.391  -0.387  -0.310  -0.574  -0.573  -0.444  -0.572  -0.541  -0.436
41    E        -0.129  -0.147  -0.214  -0.242  -0.279  -0.412  -0.174  -0.199  -0.289
42    T        -0.129  -0.108  -0.197   0.096   0.124   0.005  -0.174  -0.138  -0.264
43    L         0.994   0.944   0.898   1.067   1.004   0.964   1.020   0.917   0.819
44    S        -1.083  -0.822  -1.016  -1.119  -0.681  -1.012  -0.970  -0.631  -0.854
45    I        -1.083  -1.122  -1.078  -1.211  -1.263  -1.197  -0.970  -0.991  -0.923
46    A         2.244   2.356   2.422   2.235   2.404   2.536   2.612   2.796   2.936
47    F         2.244   2.356   2.422   2.274   2.446   2.578   2.612   2.796   2.936
48    S        -1.775  -1.708  -1.687  -1.845  -1.741  -1.707  -1.368  -1.272  -1.226
49    N         0.563   0.624   0.668   0.305   0.410   0.459   0.224   0.310   0.367
50    S        -0.129  -0.303  -0.274  -0.085  -0.391  -0.353  -0.174  -0.415  -0.377
51    P        -0.129  -0.041  -0.170   0.141   0.279   0.094  -0.174  -0.048  -0.223
52    A        -0.129  -0.303  -0.274  -0.165  -0.458  -0.425  -0.174  -0.415  -0.377
53    F        -1.083  -1.133  -1.085  -0.970  -0.995  -0.949  -0.970  -1.002  -0.932
54    H        -1.083  -1.122  -1.078  -0.967  -1.011  -0.934  -0.970  -0.991  -0.923
55    F         0.563   0.624   0.668   0.332   0.423   0.483   0.224   0.310   0.367
56    I         0.563   0.744   0.750   0.265   0.564   0.576   0.224   0.543   0.530
57    C        -0.391  -0.294  -0.302  -0.163   0.000   0.009  -0.572  -0.437  -0.430
58    K        -0.129  -0.303  -0.274  -0.108  -0.330  -0.286  -0.174  -0.415  -0.377
59    K        -0.129  -0.303  -0.274  -0.148  -0.390  -0.346  -0.174  -0.415  -0.377
60    I        -0.391  -0.412  -0.318  -0.530  -0.541  -0.396  -0.572  -0.573  -0.447
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    L        -0.353  -0.368  -0.338  -0.497  -0.547  -0.495  -0.498  -0.514  -0.469
69    N         0.839   0.741   0.759   0.855   0.693   0.751   0.746   0.537   0.549
70    I        -0.353  -0.185  -0.284  -0.497  -0.218  -0.398  -0.498  -0.244  -0.391
71    P         0.839   0.741   0.759   0.940   0.771   0.768   0.746   0.537   0.549
72    L        -1.218  -1.152  -1.117  -1.401  -1.287  -1.245  -1.119  -1.017  -0.966
73    A        -1.775  -1.708  -1.687  -1.701  -1.582  -1.557  -1.368  -1.272  -1.226
74    E        -0.129  -0.108  -0.197  -0.177  -0.136  -0.293  -0.174  -0.138  -0.264
75    K        -1.083  -1.097  -1.068  -1.102  -1.090  -1.053  -0.970  -0.966  -0.912
76    V        -1.083  -1.133  -1.085  -0.848  -0.881  -0.790  -0.970  -1.002  -0.932
77    P        -0.391  -0.236  -0.311  -0.488  -0.259  -0.342  -0.572  -0.350  -0.437
78    -         0.839   0.847   0.837   0.749   0.760   0.760   0.746   0.739   0.701
79    -        -0.353  -0.287  -0.280  -0.621  -0.521  -0.523  -0.498  -0.398  -0.386
80    -         0.839   0.816   0.822   0.952   0.902   0.899   0.746   0.681   0.673
81    T        -1.083  -1.029  -1.031  -0.946  -0.829  -0.848  -0.970  -0.887  -0.870
82    R        -0.129  -0.126  -0.204  -0.011  -0.002  -0.109  -0.174  -0.171  -0.273
83    T        -1.083  -0.822  -1.016  -1.127  -0.712  -1.018  -0.970  -0.631  -0.854
84    I        -0.391  -0.382  -0.308  -0.276  -0.205  -0.087  -0.572  -0.533  -0.432
85    T        -0.391  -0.407  -0.316  -0.532  -0.571  -0.419  -0.572  -0.567  -0.443
86    T        -1.775  -1.708  -1.687  -1.678  -1.591  -1.533  -1.368  -1.272  -1.226
87    D        -0.129  -0.086  -0.187  -0.001   0.086  -0.076  -0.174  -0.108  -0.248
88    I        -0.353  -0.175  -0.271  -0.437  -0.126  -0.311  -0.498  -0.229  -0.372
89    I        -0.353  -0.238  -0.280  -0.515  -0.327  -0.407  -0.498  -0.319  -0.385
90    S        -1.218  -1.144  -1.117  -1.209  -1.074  -1.045  -1.119  -1.010  -0.966
91    P        -1.218  -1.144  -1.117  -1.154  -1.083  -0.988  -1.119  -1.010  -0.966
92    F        -0.353  -0.369  -0.338  -0.373  -0.367  -0.348  -0.498  -0.517  -0.469
93    L        -1.218  -1.144  -1.117  -1.234  -1.113  -1.071  -1.119  -1.010  -0.966
94    D         0.839   0.729   0.759   0.796   0.612   0.643   0.746   0.516   0.549
95    S         0.654   0.703   0.690   0.541   0.609   0.558   0.401   0.465   0.411
96    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    Y        -1.083  -0.982  -1.024  -0.989  -0.802  -0.889  -0.970  -0.837  -0.863
98    G         0.563   0.618   0.664   0.326   0.404   0.464   0.224   0.298   0.359
99    E        -0.129  -0.303  -0.274  -0.114  -0.390  -0.329  -0.174  -0.415  -0.377
100   I         0.563   0.624   0.668   0.282   0.375   0.437   0.224   0.310   0.367
101   S        -1.083  -1.122  -1.078  -1.152  -1.234  -1.152  -0.970  -0.991  -0.923
102   E         2.244   2.356   2.422   2.201   2.373   2.502   2.612   2.796   2.936
103   V        -0.391  -0.387  -0.310  -0.619  -0.598  -0.480  -0.572  -0.541  -0.436
104   N        -0.129  -0.303  -0.274  -0.089  -0.362  -0.340  -0.174  -0.415  -0.377
105   T        -0.129   0.096  -0.141  -0.079   0.292  -0.090  -0.174   0.168  -0.180
106   F         0.563   0.638   0.675   0.322   0.439   0.491   0.224   0.337   0.380
107   D        -0.129  -0.303  -0.274  -0.118  -0.396  -0.373  -0.174  -0.415  -0.377
108   A         0.994   0.892   0.878   1.017   0.862   0.841   1.020   0.823   0.781
109   V         0.994   0.892   0.878   1.014   0.862   0.831   1.020   0.823   0.781
110   A         0.994   0.892   0.878   1.015   0.852   0.838   1.020   0.823   0.781
111   V        -0.129  -0.303  -0.274  -0.160  -0.457  -0.422  -0.174  -0.415  -0.377
112   W         0.994   1.250   0.963   1.427   1.819   1.396   1.020   1.446   0.941
113   S        -1.083  -1.133  -1.085  -0.894  -0.947  -0.869  -0.970  -1.002  -0.932
114   L        -1.083  -1.133  -1.085  -1.018  -1.068  -0.993  -0.970  -1.002  -0.932
115   P         2.244   2.356   2.422   2.450   2.640   2.761   2.612   2.796   2.936
116   -        -0.353  -0.164  -0.272  -0.491  -0.155  -0.373  -0.498  -0.212  -0.373
117   P        -1.775  -1.708  -1.687  -1.492  -1.418  -1.340  -1.368  -1.272  -1.226
118   H        -0.129  -0.303  -0.274   0.098  -0.208  -0.187  -0.174  -0.415  -0.377
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   V        -0.129   0.096  -0.141  -0.177   0.177  -0.202  -0.174   0.168  -0.180
127   P        -1.083  -1.133  -1.085  -0.838  -0.915  -0.836  -0.970  -1.002  -0.932
128   K        -0.129  -0.147  -0.214  -0.139  -0.187  -0.245  -0.174  -0.199  -0.289
129   A        -0.391  -0.412  -0.318  -0.560  -0.592  -0.439  -0.572  -0.573  -0.447
130   R        -0.129   0.096  -0.141  -0.135   0.210  -0.149  -0.174   0.168  -0.180
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   S        -1.083  -1.122  -1.078  -1.050  -1.162  -1.070  -0.970  -0.991  -0.923
141   N        -0.129  -0.303  -0.274  -0.001  -0.257  -0.206  -0.174  -0.415  -0.377
142   D        -0.129  -0.303  -0.274  -0.091  -0.352  -0.332  -0.174  -0.415  -0.377
143   A        -0.391  -0.412  -0.318  -0.532  -0.581  -0.435  -0.572  -0.573  -0.447
144   K        -0.353  -0.319  -0.327  -0.430  -0.371  -0.364  -0.498  -0.452  -0.454
145   F         0.994   0.944   0.898   1.030   0.948   0.874   1.020   0.917   0.819
146   N         0.994   0.892   0.878   1.056   0.901   0.872   1.020   0.823   0.781
147   K        -1.083  -1.029  -1.031  -0.946  -0.854  -0.878  -0.970  -0.887  -0.870
148   D        -0.129  -0.126  -0.204  -0.173  -0.174  -0.313  -0.174  -0.171  -0.273
149   F         0.994   0.944   0.898   1.074   1.007   0.943   1.020   0.917   0.819
150   I        -1.083  -1.122  -1.078  -1.169  -1.263  -1.182  -0.970  -0.991  -0.923
151   D        -1.775  -1.708  -1.687  -1.524  -1.408  -1.372  -1.368  -1.272  -1.226
152   D        -1.083  -1.133  -1.085  -0.989  -1.081  -0.970  -0.970  -1.002  -0.932
153   L         0.994   0.944   0.898   0.994   0.908   0.847   1.020   0.917   0.819
154   N        -0.391  -0.294  -0.302  -0.651  -0.495  -0.504  -0.572  -0.437  -0.430
155   A        -1.083  -1.029  -1.031  -1.031  -0.957  -0.947  -0.970  -0.887  -0.870
156   R        -0.129  -0.303  -0.274   0.042  -0.252  -0.229  -0.174  -0.415  -0.377
157   V        -1.083  -0.822  -1.016  -1.217  -0.790  -1.112  -0.970  -0.631  -0.854
158   K        -0.391  -0.395  -0.315  -0.709  -0.697  -0.579  -0.572  -0.552  -0.444
159   Q        -1.083  -1.122  -1.078  -1.124  -1.209  -1.107  -0.970  -0.991  -0.923
160   V        -0.129  -0.108  -0.197  -0.110  -0.056  -0.216  -0.174  -0.138  -0.264
161   I        -0.391  -0.382  -0.308  -0.615  -0.599  -0.480  -0.572  -0.533  -0.432
162   P        -0.129  -0.303  -0.274   0.019  -0.284  -0.267  -0.174  -0.415  -0.377
163   N        -1.083  -1.006  -1.024  -1.102  -0.978  -1.002  -0.970  -0.858  -0.862
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   G        -0.391  -0.395  -0.315  -0.598  -0.594  -0.485  -0.572  -0.552  -0.444
166   I        -0.129  -0.303  -0.274  -0.148  -0.455  -0.430  -0.174  -0.415  -0.377
167   N        -1.083  -1.006  -1.024  -0.785  -0.630  -0.681  -0.970  -0.858  -0.862
168   Y         0.994   0.892   0.878   1.087   0.929   0.910   1.020   0.823   0.781
169   Y         0.563   0.582   0.652   0.556   0.624   0.745   0.224   0.226   0.334
170   Y         2.244   2.356   2.422   2.307   2.485   2.612   2.612   2.796   2.936
171   L         2.244   2.356   2.422   2.221   2.382   2.523   2.612   2.796   2.936
172   F        -0.129  -0.303  -0.274  -0.123  -0.413  -0.383  -0.174  -0.415  -0.377
173   C        -1.775  -1.708  -1.687  -1.369  -1.287  -1.212  -1.368  -1.272  -1.226
174   I        -0.129  -0.303  -0.274  -0.131  -0.441  -0.404  -0.174  -0.415  -0.377
175   G         0.994   0.944   0.898   1.085   1.013   0.931   1.020   0.917   0.819
176   K        -0.129  -0.303  -0.274  -0.199  -0.459  -0.423  -0.174  -0.415  -0.377
177   N        -0.391  -0.412  -0.318  -0.563  -0.573  -0.435  -0.572  -0.573  -0.447
178   L         0.839   0.741   0.759   0.890   0.752   0.788   0.746   0.537   0.549
179   N        -1.083  -1.122  -1.078  -1.047  -1.143  -1.066  -0.970  -0.991  -0.923
180   E        -1.083  -0.822  -1.016  -1.086  -0.688  -0.968  -0.970  -0.631  -0.854
181   K        -1.083  -1.133  -1.085  -1.135  -1.198  -1.114  -0.970  -1.002  -0.932
182   G        -1.775  -1.708  -1.687  -1.556  -1.375  -1.406  -1.368  -1.272  -1.226
183   I        -0.391  -0.418  -0.318  -0.468  -0.493  -0.337  -0.572  -0.582  -0.449
184   R         0.563   0.708   0.715   0.288   0.521   0.531   0.224   0.474   0.462
185   G         2.244   2.356   2.422   2.327   2.506   2.632   2.612   2.796   2.936
186   S         0.994   0.892   0.878   1.096   0.923   0.917   1.020   0.823   0.781
187   V         0.994   0.892   0.878   0.997   0.837   0.804   1.020   0.823   0.781
188   R         0.994   0.944   0.898   1.221   1.150   1.079   1.020   0.917   0.819
189   T        -0.391  -0.280  -0.303  -0.663  -0.507  -0.517  -0.572  -0.423  -0.431
190   I         0.563   0.582   0.652   0.284   0.264   0.392   0.224   0.226   0.334
191   F         0.563   0.582   0.652   0.311   0.310   0.433   0.224   0.226   0.334
192   E        -0.129  -0.108  -0.197  -0.177  -0.136  -0.293  -0.174  -0.138  -0.264
193   E        -0.391  -0.248  -0.310  -0.493  -0.210  -0.330  -0.572  -0.361  -0.435
194   Y         0.563   0.582   0.652   0.339   0.339   0.458   0.224   0.226   0.334
195   K        -0.129  -0.303  -0.274  -0.261  -0.554  -0.518  -0.174  -0.415  -0.377
196   R        -1.083  -1.122  -1.078  -1.169  -1.220  -1.145  -0.970  -0.991  -0.923
197   R        -0.129  -0.303  -0.274   0.062  -0.240  -0.199  -0.174  -0.415  -0.377
198   A         0.994   0.892   0.878   1.088   0.965   0.959   1.020   0.823   0.781
199   D         0.994   0.944   0.898   1.004   0.936   0.835   1.020   0.917   0.819
200   E        -1.083  -1.097  -1.068  -1.077  -1.064  -1.037  -0.970  -0.966  -0.912
201   E         0.994   0.944   0.898   0.982   0.905   0.840   1.020   0.917   0.819
202   N         0.994   0.892   0.878   1.069   0.922   0.893   1.020   0.823   0.781
203   C        -0.129  -0.303  -0.274   0.143  -0.182  -0.168  -0.174  -0.415  -0.377
204   A        -0.129  -0.303  -0.274  -0.083  -0.346  -0.300  -0.174  -0.415  -0.377
205   I        -0.129  -0.108  -0.197  -0.017   0.001  -0.107  -0.174  -0.138  -0.264
206   V         0.563   0.582   0.652   0.294   0.316   0.423   0.224   0.226   0.334
207   L         0.994   0.944   0.898   0.982   0.898   0.829   1.020   0.917   0.819
208   E         2.244   2.356   2.422   2.201   2.373   2.502   2.612   2.796   2.936
209   A         0.994   0.892   0.878   1.015   0.852   0.838   1.020   0.823   0.781
210   I         0.994   0.892   0.878   1.067   0.900   0.890   1.020   0.823   0.781
211   A        -1.083  -1.133  -1.085  -0.981  -1.014  -0.950  -0.970  -1.002  -0.932
212   E        -1.083  -1.133  -1.085  -1.188  -1.277  -1.198  -0.970  -1.002  -0.932
213   H         0.994   1.166   0.934   1.254   1.535   1.155   1.020   1.307   0.887
214   A         0.994   0.892   0.878   1.007   0.848   0.825   1.020   0.823   0.781
215   K         0.563   0.708   0.715   0.375   0.655   0.630   0.224   0.474   0.462
216   S        -0.129  -0.303  -0.274  -0.019  -0.294  -0.252  -0.174  -0.415  -0.377
217   V         0.563   0.582   0.652   0.282   0.293   0.408   0.224   0.226   0.334
218   Y         2.244   2.356   2.422   2.307   2.485   2.612   2.612   2.796   2.936
219   E         0.994   0.944   0.898   0.971   0.896   0.822   1.020   0.917   0.819
220   Y         0.563   0.582   0.652   0.473   0.522   0.635   0.224   0.226   0.334
221   F         0.994   0.944   0.898   1.030   0.948   0.874   1.020   0.917   0.819
222   G         2.244   2.356   2.422   2.327   2.506   2.632   2.612   2.796   2.936
223   F         2.244   2.356   2.422   2.274   2.446   2.578   2.612   2.796   2.936
224   R        -1.083  -1.097  -1.068  -1.077  -1.114  -1.094  -0.970  -0.966  -0.912
225   N        -0.129  -0.303  -0.274  -0.104  -0.386  -0.362  -0.174  -0.415  -0.377
226   Y        -0.129  -0.303  -0.274   0.054  -0.187  -0.135  -0.174  -0.415  -0.377
227   M        -1.775  -1.708  -1.687  -1.605  -1.473  -1.456  -1.368  -1.272  -1.226
228   T        -0.391  -0.248  -0.310  -0.466  -0.246  -0.335  -0.572  -0.361  -0.435
229   F         0.994   0.892   0.878   1.046   0.884   0.864   1.020   0.823   0.781
230   K        -1.083  -0.957  -1.013  -0.994  -0.786  -0.874  -0.970  -0.804  -0.849
231   Y        -1.083  -1.133  -1.085  -1.110  -1.212  -1.133  -0.970  -1.002  -0.932
232   G         0.994   0.892   0.878   1.125   0.983   0.961   1.020   0.823   0.781
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   E        -1.083  -0.973  -1.016  -1.135  -0.982  -1.026  -0.970  -0.822  -0.853
251   C        -1.083  -1.029  -1.031  -0.915  -0.841  -0.817  -0.970  -0.887  -0.870
252   E         0.563   0.582   0.652   0.163   0.153   0.263   0.224   0.226   0.334
253   V        -0.129  -0.303  -0.274  -0.156  -0.447  -0.416  -0.174  -0.415  -0.377
254   D        -0.129  -0.082  -0.186  -0.141  -0.075  -0.248  -0.174  -0.113  -0.247
255   S        -0.129  -0.082  -0.186  -0.009   0.060  -0.089  -0.174  -0.113  -0.247
256   N        -1.083  -1.029  -1.031  -0.925  -0.847  -0.854  -0.970  -0.887  -0.870
257   G         0.994   0.892   0.878   1.085   0.926   0.894   1.020   0.823   0.781
258   N        -0.129  -0.082  -0.186  -0.058  -0.028  -0.143  -0.174  -0.113  -0.247
259   C        -1.083  -1.006  -1.024  -0.831  -0.695  -0.725  -0.970  -0.858  -0.862
260   D         0.563   0.582   0.652   0.221   0.215   0.315   0.224   0.226   0.334
261   P        -0.129  -0.303  -0.274   0.015  -0.290  -0.273  -0.174  -0.415  -0.377
262   N         0.994   0.892   0.878   1.046   0.887   0.855   1.020   0.823   0.781
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   G         0.994   0.892   0.878   1.085   0.926   0.894   1.020   0.823   0.781
273   E         0.994   1.250   0.963   0.938   1.326   0.886   1.020   1.446   0.941
274   G         0.994   0.892   0.878   1.062   0.896   0.857   1.020   0.823   0.781
275   F        -0.129  -0.303  -0.274  -0.123  -0.418  -0.383  -0.174  -0.415  -0.377
276   T        -0.391  -0.248  -0.310  -0.593  -0.374  -0.486  -0.572  -0.361  -0.435
277   A        -0.129  -0.086  -0.187  -0.089  -0.017  -0.200  -0.174  -0.108  -0.248
278   Y        -1.083  -1.133  -1.085  -0.973  -1.065  -0.962  -0.970  -1.002  -0.932
279   L         2.244   2.356   2.422   2.221   2.382   2.523   2.612   2.796   2.936
280   M         0.994   0.892   0.878   1.332   1.167   1.141   1.020   0.823   0.781
281   I         0.563   0.582   0.652   0.296   0.293   0.407   0.224   0.226   0.334
282   Y        -0.129  -0.303  -0.274  -0.066  -0.360  -0.317  -0.174  -0.415  -0.377
283   H        -1.083  -1.133  -1.085  -0.889  -0.991  -0.921  -0.970  -1.002  -0.932
284   K        -0.129  -0.303  -0.274  -0.199  -0.458  -0.423  -0.174  -0.415  -0.377
285   D         0.994   0.892   0.878   1.080   0.957   0.924   1.020   0.823   0.781
286   G         0.654   0.703   0.690   0.509   0.576   0.518   0.401   0.465   0.411
287   N        -0.500  -0.454  -0.383  -0.775  -0.697  -0.594  -0.705  -0.629  -0.533
288   K         0.654   0.703   0.690   0.414   0.484   0.461   0.401   0.465   0.411
289   V         0.654   0.703   0.690   0.495   0.567   0.528   0.401   0.465   0.411
290   L         0.654   0.703   0.690   0.466   0.534   0.483   0.401   0.465   0.411
291   K        -1.218  -1.144  -1.117  -1.365  -1.258  -1.208  -1.119  -1.010  -0.966
292   E        -0.353  -0.383  -0.347  -0.370  -0.376  -0.323  -0.498  -0.535  -0.482
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04170
Output conservation file - output/Q04170
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
