1     M         2.271   2.277   2.318   2.697   2.708   2.778   2.509   2.519   2.582
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    T        -0.553  -0.549  -0.523  -0.467  -0.462  -0.417  -0.619  -0.613  -0.574
39    V        -0.553  -0.549  -0.523  -0.378  -0.381  -0.327  -0.619  -0.613  -0.574
40    I         0.635   0.620   0.615   0.667   0.645   0.640   0.424   0.396   0.377
41    K         2.271   2.277   2.318   1.969   1.981   2.044   2.509   2.519   2.582
42    T        -0.553  -0.549  -0.523  -0.944  -0.950  -0.898  -0.619  -0.613  -0.574
43    E         2.271   2.277   2.318   2.216   2.228   2.292   2.509   2.519   2.582
44    P         0.635   0.626   0.621   0.667   0.653   0.640   0.424   0.407   0.387
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    T         0.635   0.626   0.621   0.758   0.744   0.735   0.424   0.407   0.387
48    T         0.635   0.626   0.621   0.713   0.699   0.684   0.424   0.407   0.387
49    E         0.635   0.626   0.621   0.433   0.418   0.401   0.424   0.407   0.387
50    V        -0.553  -0.549  -0.523  -0.689  -0.696  -0.641  -0.619  -0.613  -0.574
51    T        -0.553  -0.549  -0.523  -0.663  -0.661  -0.614  -0.619  -0.613  -0.574
52    L        -0.553  -0.549  -0.523  -0.442  -0.426  -0.392  -0.619  -0.613  -0.574
53    Y        -0.553  -0.549  -0.523  -0.174  -0.170  -0.121  -0.619  -0.613  -0.574
54    S         0.635   0.626   0.621   0.228   0.210   0.174   0.424   0.407   0.387
55    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    K         0.635   0.599   0.615   0.197   0.137   0.149   0.424   0.359   0.377
59    E        -0.553  -0.548  -0.523  -0.601  -0.591  -0.552  -0.619  -0.611  -0.574
60    S        -0.553  -0.548  -0.523  -0.674  -0.659  -0.626  -0.619  -0.611  -0.574
61    L        -0.553  -0.548  -0.523  -0.935  -0.915  -0.890  -0.619  -0.611  -0.574
62    S        -0.401  -0.421  -0.427  -0.565  -0.593  -0.611  -0.424  -0.449  -0.451
63    K         0.825   0.841   0.756   0.655   0.682   0.561   0.749   0.775   0.625
64    D        -1.292  -1.289  -1.267  -0.861  -0.861  -0.815  -1.010  -1.005  -0.969
65    D        -0.401  -0.423  -0.433  -0.320  -0.360  -0.373  -0.424  -0.452  -0.459
66    A        -0.401  -0.372  -0.413  -0.449  -0.404  -0.461  -0.424  -0.383  -0.432
67    H         0.825   0.841   0.756   1.229   1.251   1.114   0.749   0.775   0.625
68    R        -0.401  -0.423  -0.433  -0.323  -0.364  -0.400  -0.424  -0.452  -0.459
69    K        -0.401  -0.423  -0.433  -0.574  -0.588  -0.606  -0.424  -0.452  -0.459
70    K        -0.401  -0.423  -0.433  -0.610  -0.640  -0.647  -0.424  -0.452  -0.459
71    Q        -0.401  -0.421  -0.427  -0.475  -0.513  -0.547  -0.424  -0.449  -0.451
72    N        -0.401  -0.421  -0.427  -0.337  -0.373  -0.381  -0.424  -0.449  -0.451
73    N         0.489   0.494   0.526   0.092   0.095   0.144   0.163   0.170   0.216
74    K        -0.401  -0.372  -0.413  -0.478  -0.414  -0.518  -0.424  -0.383  -0.432
75    P        -0.401  -0.421  -0.427  -0.382  -0.420  -0.437  -0.424  -0.449  -0.451
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    N         0.635   0.626   0.621   0.652   0.636   0.621   0.424   0.407   0.387
88    S        -1.292  -1.289  -1.267  -1.140  -1.133  -1.096  -1.010  -1.005  -0.969
89    R        -1.292  -1.289  -1.267  -1.118  -1.118  -1.074  -1.010  -1.005  -0.969
90    S         0.825   0.841   0.756   0.822   0.847   0.726   0.749   0.775   0.625
91    G        -1.292  -1.289  -1.267  -1.030  -1.031  -0.985  -1.010  -1.005  -0.969
92    P         2.271   2.277   2.318   2.429   2.442   2.508   2.509   2.519   2.582
93    N        -0.401  -0.374  -0.413  -0.382  -0.339  -0.411  -0.424  -0.386  -0.432
94    K         0.825   0.779   0.741   0.701   0.644   0.597   0.749   0.671   0.598
95    H        -1.292  -1.289  -1.267  -0.992  -1.011  -0.947  -1.010  -1.005  -0.969
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    K         0.635   0.626   0.621   0.319   0.307   0.306   0.424   0.407   0.387
99    L         0.635   0.620   0.615   0.497   0.469   0.463   0.424   0.396   0.377
100   A        -0.553  -0.549  -0.523  -0.533  -0.532  -0.483  -0.619  -0.613  -0.574
101   A        -0.553  -0.549  -0.523  -0.626  -0.627  -0.577  -0.619  -0.613  -0.574
102   K         0.635   0.620   0.615   0.336   0.316   0.318   0.424   0.396   0.377
103   A        -0.553  -0.549  -0.523  -0.492  -0.487  -0.442  -0.619  -0.613  -0.574
104   P         0.635   0.620   0.615   0.660   0.634   0.622   0.424   0.396   0.377
105   E        -0.553  -0.549  -0.523  -0.864  -0.855  -0.818  -0.619  -0.613  -0.574
106   K         0.635   0.620   0.615   0.262   0.240   0.233   0.424   0.396   0.377
107   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   D         0.635   0.620   0.615   0.552   0.519   0.495   0.424   0.396   0.377
113   K         0.635   0.626   0.621   0.143   0.128   0.108   0.424   0.407   0.387
114   Q        -0.553  -0.549  -0.523  -0.679  -0.683  -0.630  -0.619  -0.613  -0.574
115   D         0.635   0.673   0.634   0.652   0.717   0.646   0.424   0.489   0.411
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   L         0.635   0.626   0.621   0.441   0.422   0.409   0.424   0.407   0.387
118   S         2.271   2.277   2.318   2.181   2.194   2.257   2.509   2.519   2.582
119   A        -0.553  -0.549  -0.523  -0.904  -0.915  -0.858  -0.619  -0.613  -0.574
120   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   P         2.271   2.277   2.318   2.402   2.414   2.481   2.509   2.519   2.582
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   S        -0.401  -0.423  -0.433  -0.423  -0.452  -0.462  -0.424  -0.452  -0.459
132   L        -0.401  -0.374  -0.413  -0.354  -0.306  -0.373  -0.424  -0.386  -0.432
133   I        -0.401  -0.372  -0.413  -0.647  -0.598  -0.659  -0.424  -0.383  -0.432
134   V        -1.292  -1.289  -1.267  -1.209  -1.192  -1.166  -1.010  -1.005  -0.969
135   K        -0.401  -0.372  -0.413  -0.619  -0.562  -0.646  -0.424  -0.383  -0.432
136   P         0.825   0.779   0.741   0.903   0.822   0.747   0.749   0.671   0.598
137   S         0.489   0.494   0.527   0.344   0.360   0.411   0.163   0.170   0.217
138   E        -0.401  -0.423  -0.433  -0.484  -0.510  -0.531  -0.424  -0.452  -0.459
139   S        -0.401  -0.421  -0.427  -0.258  -0.282  -0.272  -0.424  -0.449  -0.451
140   K        -1.292  -1.289  -1.267  -1.341  -1.338  -1.299  -1.010  -1.005  -0.969
141   K        -1.292  -1.289  -1.267  -1.361  -1.336  -1.319  -1.010  -1.005  -0.969
142   K        -1.292  -1.289  -1.267  -1.055  -1.033  -1.010  -1.010  -1.005  -0.969
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   E        -0.401  -0.372  -0.413  -0.400  -0.350  -0.425  -0.424  -0.383  -0.432
159   N        -0.401  -0.374  -0.413  -0.610  -0.570  -0.631  -0.424  -0.386  -0.432
160   I        -0.553  -0.549  -0.523  -0.716  -0.712  -0.668  -0.619  -0.613  -0.574
161   V        -0.553  -0.549  -0.523  -0.548  -0.555  -0.499  -0.619  -0.613  -0.574
162   A        -0.553  -0.549  -0.523  -0.663  -0.662  -0.614  -0.619  -0.613  -0.574
163   Y        -0.553  -0.549  -0.523  -0.320  -0.321  -0.268  -0.619  -0.613  -0.574
164   N         0.635   0.620   0.615   0.732   0.707   0.702   0.424   0.396   0.377
165   D        -0.553  -0.549  -0.523  -0.776  -0.775  -0.728  -0.619  -0.613  -0.574
166   T        -0.553  -0.549  -0.523  -0.663  -0.660  -0.614  -0.619  -0.613  -0.574
167   P         2.271   2.277   2.318   2.402   2.414   2.481   2.509   2.519   2.582
168   G         0.635   0.620   0.615   0.817   0.787   0.777   0.424   0.396   0.377
169   I        -0.553  -0.549  -0.523  -0.743  -0.740  -0.695  -0.619  -0.613  -0.574
170   K         2.271   2.277   2.318   1.969   1.981   2.044   2.509   2.519   2.582
171   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   P        -0.553  -0.548  -0.523  -0.408  -0.399  -0.357  -0.619  -0.612  -0.574
179   L         0.635   0.660   0.634   0.359   0.403   0.342   0.424   0.466   0.411
180   T        -0.401  -0.423  -0.433  -0.452  -0.490  -0.525  -0.424  -0.452  -0.459
181   P         0.489   0.494   0.527   0.252   0.256   0.307   0.163   0.170   0.217
182   I        -1.292  -1.289  -1.267  -1.108  -1.118  -1.063  -1.010  -1.005  -0.969
183   S         0.825   0.841   0.756   0.781   0.807   0.675   0.749   0.775   0.625
184   K        -0.401  -0.421  -0.427  -0.604  -0.628  -0.632  -0.424  -0.449  -0.451
185   K         0.825   0.779   0.741   0.614   0.548   0.487   0.749   0.671   0.598
186   R        -0.401  -0.413  -0.413  -0.323  -0.357  -0.349  -0.424  -0.439  -0.432
187   A         0.825   0.844   0.766   1.044   1.069   0.959   0.749   0.780   0.641
188   L        -0.401  -0.421  -0.427  -0.417  -0.443  -0.441  -0.424  -0.449  -0.451
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   K        -0.401  -0.421  -0.427  -0.417  -0.439  -0.426  -0.424  -0.449  -0.451
191   E        -0.401  -0.421  -0.427  -0.722  -0.763  -0.787  -0.424  -0.449  -0.451
192   K        -1.292  -1.289  -1.267  -1.284  -1.273  -1.241  -1.010  -1.005  -0.969
193   A        -0.553  -0.549  -0.523  -0.383  -0.378  -0.332  -0.619  -0.613  -0.574
194   A        -0.553  -0.549  -0.523  -0.631  -0.633  -0.582  -0.619  -0.613  -0.574
195   S        -0.553  -0.549  -0.523  -0.776  -0.762  -0.728  -0.619  -0.613  -0.574
196   E         0.635   0.620   0.615   0.360   0.332   0.308   0.424   0.396   0.377
197   K        -0.553  -0.549  -0.523  -0.754  -0.730  -0.706  -0.619  -0.613  -0.574
198   C        -0.553  -0.549  -0.523  -0.732  -0.748  -0.684  -0.619  -0.613  -0.574
199   D        -0.553  -0.549  -0.523  -0.689  -0.688  -0.641  -0.619  -0.613  -0.574
200   S         0.635   0.626   0.621   0.465   0.453   0.442   0.424   0.407   0.387
201   F         0.635   0.626   0.621   0.898   0.881   0.862   0.424   0.407   0.387
202   D        -0.553  -0.549  -0.523  -0.518  -0.512  -0.468  -0.619  -0.613  -0.574
203   L         2.271   2.277   2.318   2.224   2.232   2.301   2.509   2.519   2.582
204   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   Y        -0.553  -0.548  -0.523  -0.364  -0.348  -0.312  -0.619  -0.611  -0.574
211   I        -0.553  -0.548  -0.523  -0.612  -0.620  -0.563  -0.619  -0.611  -0.574
212   Q        -0.553  -0.548  -0.523  -0.624  -0.615  -0.575  -0.619  -0.611  -0.574
213   K         0.635   0.659   0.637   0.197   0.248   0.190   0.424   0.466   0.417
214   K        -1.292  -1.289  -1.267  -1.334  -1.336  -1.292  -1.010  -1.005  -0.969
215   S        -0.401  -0.372  -0.413  -0.568  -0.522  -0.585  -0.424  -0.383  -0.432
216   K        -1.292  -1.289  -1.267  -1.341  -1.325  -1.299  -1.010  -1.005  -0.969
217   T        -0.401  -0.374  -0.413  -0.314  -0.273  -0.332  -0.424  -0.386  -0.432
218   L        -0.401  -0.372  -0.413  -0.371  -0.319  -0.397  -0.424  -0.383  -0.432
219   S        -1.292  -1.289  -1.267  -1.464  -1.450  -1.423  -1.010  -1.005  -0.969
220   S        -0.401  -0.423  -0.433  -0.388  -0.415  -0.423  -0.424  -0.452  -0.459
221   V        -0.401  -0.421  -0.427  -0.323  -0.366  -0.392  -0.424  -0.449  -0.451
222   T        -0.553  -0.548  -0.523  -0.569  -0.575  -0.520  -0.619  -0.612  -0.574
223   E        -0.553  -0.548  -0.523  -0.569  -0.565  -0.520  -0.619  -0.612  -0.574
224   I        -0.553  -0.548  -0.523  -0.499  -0.474  -0.449  -0.619  -0.612  -0.574
225   N        -0.553  -0.548  -0.523  -0.790  -0.796  -0.743  -0.619  -0.612  -0.574
226   S         0.635   0.660   0.634   0.537   0.585   0.522   0.424   0.466   0.411
227   S        -0.553  -0.548  -0.523  -0.802  -0.787  -0.755  -0.619  -0.612  -0.574
228   E        -0.553  -0.548  -0.523  -0.790  -0.775  -0.743  -0.619  -0.612  -0.574
229   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   N        -0.553  -0.548  -0.523  -0.467  -0.457  -0.416  -0.619  -0.612  -0.574
238   T        -0.553  -0.548  -0.523  -0.515  -0.507  -0.465  -0.619  -0.612  -0.574
239   S        -0.553  -0.548  -0.523  -0.681  -0.687  -0.633  -0.619  -0.612  -0.574
240   S         2.271   2.277   2.318   2.203   2.218   2.279   2.509   2.519   2.582
241   P         2.271   2.277   2.318   2.482   2.494   2.561   2.509   2.519   2.582
242   A        -0.553  -0.548  -0.523  -0.580  -0.575  -0.531  -0.619  -0.612  -0.574
243   K         0.635   0.660   0.634   0.645   0.695   0.621   0.424   0.466   0.411
244   E        -0.553  -0.548  -0.523  -0.558  -0.553  -0.509  -0.619  -0.612  -0.574
245   K         2.271   2.277   2.318   2.054   2.070   2.129   2.509   2.519   2.582
246   S         0.635   0.660   0.634   0.579   0.629   0.563   0.424   0.466   0.411
247   Q        -0.553  -0.548  -0.523  -0.653  -0.653  -0.604  -0.619  -0.612  -0.574
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   E         0.489   0.494   0.526  -0.042  -0.034   0.011   0.163   0.170   0.216
253   P        -0.401  -0.423  -0.433  -0.403  -0.449  -0.470  -0.424  -0.452  -0.459
254   I        -1.292  -1.289  -1.267  -0.962  -0.946  -0.916  -1.010  -1.005  -0.969
255   E        -0.401  -0.423  -0.433  -0.744  -0.787  -0.824  -0.424  -0.452  -0.459
256   N        -0.401  -0.421  -0.427  -0.405  -0.447  -0.457  -0.424  -0.449  -0.451
257   P         2.271   2.277   2.318   2.429   2.442   2.508   2.509   2.519   2.582
258   G         0.825   0.779   0.741   1.029   0.945   0.871   0.749   0.671   0.598
259   S        -0.401  -0.372  -0.413  -0.703  -0.649  -0.720  -0.424  -0.383  -0.432
260   Y        -0.401  -0.421  -0.427   0.125   0.094   0.097  -0.424  -0.449  -0.451
261   Q        -0.401  -0.372  -0.413  -0.595  -0.543  -0.620  -0.424  -0.383  -0.432
262   K         0.825   0.779   0.741   0.704   0.647   0.599   0.749   0.671   0.598
263   T        -0.401  -0.374  -0.413  -0.334  -0.288  -0.362  -0.424  -0.386  -0.432
264   R        -0.553  -0.549  -0.523  -0.413  -0.413  -0.362  -0.619  -0.613  -0.574
265   N        -0.553  -0.549  -0.523  -0.548  -0.547  -0.499  -0.619  -0.613  -0.574
266   Y        -0.553  -0.549  -0.523  -0.388  -0.392  -0.337  -0.619  -0.613  -0.574
267   L         2.271   2.277   2.318   2.224   2.232   2.301   2.509   2.519   2.582
268   F        -0.553  -0.549  -0.523  -0.230  -0.228  -0.177  -0.619  -0.613  -0.574
269   E         2.271   2.277   2.318   2.216   2.228   2.292   2.509   2.519   2.582
270   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   P         0.635   0.659   0.637   0.699   0.742   0.703   0.424   0.466   0.417
272   D        -1.292  -1.289  -1.267  -1.239  -1.245  -1.196  -1.010  -1.005  -0.969
273   P         0.489   0.493   0.526   0.382   0.388   0.441   0.163   0.169   0.215
274   L        -1.292  -1.289  -1.267  -0.996  -0.994  -0.950  -1.010  -1.005  -0.969
275   D        -0.401  -0.413  -0.413  -0.374  -0.404  -0.399  -0.424  -0.439  -0.432
276   T        -1.292  -1.289  -1.267  -1.108  -1.092  -1.063  -1.010  -1.005  -0.969
277   C        -0.401  -0.374  -0.413  -0.239  -0.200  -0.251  -0.424  -0.386  -0.432
278   L        -1.292  -1.289  -1.267  -1.239  -1.236  -1.196  -1.010  -1.005  -0.969
279   Q        -0.401  -0.374  -0.413  -0.434  -0.387  -0.463  -0.424  -0.386  -0.432
280   D        -0.401  -0.374  -0.413  -0.212  -0.171  -0.221  -0.424  -0.386  -0.432
281   Y        -0.401  -0.421  -0.427   0.145   0.114   0.119  -0.424  -0.449  -0.451
282   S        -1.292  -1.289  -1.267  -1.069  -1.050  -1.024  -1.010  -1.005  -0.969
283   S        -0.401  -0.413  -0.413  -0.484  -0.493  -0.499  -0.424  -0.439  -0.432
284   M        -0.401  -0.374  -0.413  -0.128  -0.089  -0.129  -0.424  -0.386  -0.432
285   L         0.489   0.493   0.526   0.377   0.372   0.434   0.163   0.169   0.215
286   P        -0.401  -0.423  -0.433  -0.351  -0.385  -0.412  -0.424  -0.452  -0.459
287   S        -1.292  -1.289  -1.267  -1.235  -1.225  -1.192  -1.010  -1.005  -0.969
288   N        -1.292  -1.289  -1.267  -1.243  -1.241  -1.200  -1.010  -1.005  -0.969
289   V        -0.401  -0.413  -0.413  -0.541  -0.573  -0.560  -0.424  -0.439  -0.432
290   A        -1.292  -1.289  -1.267  -0.972  -0.958  -0.926  -1.010  -1.005  -0.969
291   E         0.825   0.841   0.756   0.655   0.683   0.520   0.749   0.775   0.625
292   E        -0.401  -0.423  -0.433  -0.426  -0.460  -0.466  -0.424  -0.452  -0.459
293   D        -0.401  -0.413  -0.413  -0.478  -0.499  -0.493  -0.424  -0.439  -0.432
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   Q         0.635   0.663   0.634   0.362   0.411   0.364   0.424   0.472   0.410
312   E         0.635   0.663   0.634   0.546   0.597   0.530   0.424   0.472   0.410
313   Y         2.271   2.277   2.318   2.648   2.659   2.728   2.509   2.519   2.582
314   F        -0.401  -0.413  -0.413   0.107   0.080   0.091  -0.424  -0.439  -0.432
315   I        -0.401  -0.421  -0.427  -0.368  -0.412  -0.413  -0.424  -0.449  -0.451
316   S        -0.401  -0.374  -0.413  -0.326  -0.275  -0.353  -0.424  -0.386  -0.432
317   V        -1.292  -1.289  -1.267  -1.273  -1.271  -1.230  -1.010  -1.005  -0.969
318   A        -0.401  -0.421  -0.427  -0.437  -0.479  -0.499  -0.424  -0.449  -0.451
319   D        -0.401  -0.374  -0.413  -0.511  -0.476  -0.524  -0.424  -0.386  -0.432
320   S        -0.401  -0.383  -0.409  -0.201  -0.176  -0.190  -0.424  -0.398  -0.427
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   T        -0.401  -0.383  -0.409  -0.377  -0.346  -0.396  -0.424  -0.398  -0.427
325   L        -0.401  -0.423  -0.433  -0.420  -0.447  -0.452  -0.424  -0.452  -0.459
326   E        -1.292  -1.289  -1.267  -1.307  -1.292  -1.264  -1.010  -1.005  -0.969
327   E         0.489   0.493   0.526   0.291   0.294   0.348   0.163   0.169   0.215
328   W         2.271   2.277   2.318   2.766   2.778   2.848   2.509   2.519   2.582
329   T        -0.401  -0.413  -0.413  -0.311  -0.331  -0.327  -0.424  -0.439  -0.432
330   N        -1.292  -1.289  -1.267  -1.361  -1.354  -1.319  -1.010  -1.005  -0.969
331   K         0.825   0.844   0.766   0.537   0.572   0.433   0.749   0.780   0.641
332   G         2.271   2.277   2.318   2.558   2.569   2.638   2.509   2.519   2.582
333   Q        -0.401  -0.421  -0.427  -0.423  -0.468  -0.488  -0.424  -0.449  -0.451
334   E        -0.401  -0.383  -0.409  -0.478  -0.450  -0.488  -0.424  -0.398  -0.427
335   I         0.825   0.779   0.741   0.918   0.846   0.781   0.749   0.671   0.598
336   I        -0.401  -0.413  -0.413  -0.514  -0.534  -0.527  -0.424  -0.439  -0.432
337   D        -0.401  -0.383  -0.409  -0.397  -0.366  -0.415  -0.424  -0.398  -0.427
338   Q        -0.401  -0.374  -0.413  -0.320  -0.276  -0.343  -0.424  -0.386  -0.432
339   Q         0.825   0.844   0.766   1.122   1.150   1.045   0.749   0.780   0.641
340   F        -1.292  -1.289  -1.267  -0.732  -0.733  -0.684  -1.010  -1.005  -0.969
341   Q        -1.292  -1.289  -1.267  -1.083  -1.074  -1.038  -1.010  -1.005  -0.969
342   L         0.825   0.844   0.766   0.710   0.736   0.616   0.749   0.780   0.641
343   Y        -1.292  -1.289  -1.267  -0.735  -0.742  -0.687  -1.010  -1.005  -0.969
344   Q        -1.292  -1.289  -1.267  -1.013  -1.018  -0.968  -1.010  -1.005  -0.969
345   E        -0.401  -0.372  -0.413  -0.400  -0.340  -0.440  -0.424  -0.383  -0.432
346   I        -0.401  -0.423  -0.433  -0.309  -0.355  -0.357  -0.424  -0.452  -0.459
347   I         0.489   0.494   0.527   0.485   0.499   0.552   0.163   0.170   0.217
348   K        -0.401  -0.423  -0.433  -0.499  -0.519  -0.523  -0.424  -0.452  -0.459
349   K        -0.401  -0.423  -0.433  -0.613  -0.643  -0.650  -0.424  -0.452  -0.459
350   R         2.271   2.277   2.318   2.564   2.573   2.644   2.509   2.519   2.582
351   I         0.825   0.779   0.741   0.846   0.766   0.690   0.749   0.671   0.598
352   E        -0.401  -0.423  -0.433  -0.541  -0.564  -0.595  -0.424  -0.452  -0.459
353   L         2.271   2.277   2.318   2.163   2.169   2.239   2.509   2.519   2.582
354   S         0.825   0.779   0.741   0.688   0.610   0.534   0.749   0.671   0.598
355   Y        -0.401  -0.423  -0.433   0.059   0.019   0.014  -0.424  -0.452  -0.459
356   K        -0.401  -0.372  -0.413  -0.326  -0.268  -0.360  -0.424  -0.383  -0.432
357   F         2.271   2.277   2.318   2.647   2.657   2.728   2.509   2.519   2.582
358   K        -1.292  -1.289  -1.267  -1.133  -1.109  -1.089  -1.010  -1.005  -0.969
359   G        -1.292  -1.289  -1.267  -0.911  -0.898  -0.865  -1.010  -1.005  -0.969
360   I         0.489   0.494   0.526   0.168   0.169   0.222   0.163   0.170   0.216
361   I        -0.401  -0.423  -0.433  -0.426  -0.460  -0.488  -0.424  -0.452  -0.459
362   S        -0.401  -0.372  -0.413  -0.388  -0.338  -0.412  -0.424  -0.383  -0.432
363   V        -0.401  -0.423  -0.433  -0.149  -0.189  -0.209  -0.424  -0.452  -0.459
364   I         0.825   0.844   0.766   0.846   0.878   0.736   0.749   0.780   0.641
365   N         0.825   0.844   0.766   0.931   0.960   0.834   0.749   0.780   0.641
366   D         0.825   0.841   0.756   0.888   0.912   0.765   0.749   0.775   0.625
367   R         0.825   0.779   0.741   1.191   1.121   1.072   0.749   0.671   0.598
368   A         2.271   2.277   2.318   2.442   2.451   2.521   2.509   2.519   2.582
369   D        -0.401  -0.413  -0.413  -0.559  -0.584  -0.580  -0.424  -0.439  -0.432
370   A        -0.401  -0.423  -0.433  -0.461  -0.508  -0.538  -0.424  -0.452  -0.459
371   L         2.271   2.277   2.318   2.163   2.169   2.239   2.509   2.519   2.582
372   E        -0.401  -0.383  -0.409  -0.323  -0.296  -0.321  -0.424  -0.398  -0.427
373   E        -1.292  -1.289  -1.267  -1.388  -1.373  -1.347  -1.010  -1.005  -0.969
374   Q        -0.401  -0.421  -0.427  -0.103  -0.140  -0.134  -0.424  -0.449  -0.451
375   G         0.825   0.779   0.741   1.154   1.083   1.028   0.749   0.671   0.598
376   Q        -1.292  -1.289  -1.267  -1.115  -1.104  -1.071  -1.010  -1.005  -0.969
377   Q        -1.292  -1.289  -1.267  -1.009  -1.009  -0.964  -1.010  -1.005  -0.969
378   L        -0.401  -0.421  -0.427  -0.420  -0.444  -0.445  -0.424  -0.449  -0.451
379   E         0.825   0.858   0.769   0.888   0.939   0.788   0.749   0.802   0.646
380   G        -1.292  -1.289  -1.267  -1.136  -1.135  -1.092  -1.010  -1.005  -0.969
381   K         2.271   2.277   2.318   2.039   2.055   2.114   2.509   2.519   2.582
382   I        -0.401  -0.413  -0.413  -0.443  -0.457  -0.450  -0.424  -0.439  -0.432
383   K        -0.401  -0.383  -0.409  -0.703  -0.670  -0.714  -0.424  -0.398  -0.427
384   K         0.825   0.779   0.741   0.657   0.595   0.541   0.749   0.671   0.598
385   V         0.825   0.779   0.741   1.130   1.054   0.988   0.749   0.671   0.598
386   K        -0.401  -0.423  -0.433  -0.455  -0.472  -0.474  -0.424  -0.452  -0.459
387   T        -1.292  -1.289  -1.267  -1.217  -1.201  -1.173  -1.010  -1.005  -0.969
388   L         2.271   2.277   2.318   2.163   2.169   2.239   2.509   2.519   2.582
389   A        -0.401  -0.413  -0.413  -0.152  -0.176  -0.171  -0.424  -0.439  -0.432
390   N         0.825   0.841   0.756   0.826   0.853   0.690   0.749   0.775   0.625
391   E         2.271   2.277   2.318   2.217   2.229   2.294   2.509   2.519   2.582
392   I         0.825   0.779   0.741   1.002   0.938   0.887   0.749   0.671   0.598
393   L         2.271   2.277   2.318   2.163   2.169   2.239   2.509   2.519   2.582
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   N         0.489   0.494   0.527   0.353   0.358   0.414   0.163   0.170   0.217
396   I         0.825   0.841   0.756   0.846   0.873   0.718   0.749   0.775   0.625
397   I        -0.401  -0.413  -0.413  -0.523  -0.544  -0.536  -0.424  -0.439  -0.432
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04110
Output conservation file - output/Q04110
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
