1     M         1.999   2.011   2.050   2.252   2.273   2.334   2.186   2.203   2.261
2     S        -1.179  -1.171  -1.147  -1.162  -1.147  -1.110  -0.969  -0.958  -0.917
3     N        -0.384  -0.422  -0.423  -0.413  -0.473  -0.470  -0.444  -0.491  -0.486
4     T         0.540   0.555   0.542   0.409   0.431   0.408   0.316   0.341   0.306
5     V        -0.519  -0.515  -0.484  -0.626  -0.614  -0.570  -0.619  -0.610  -0.564
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     R        -0.519  -0.511  -0.484  -0.392  -0.375  -0.334  -0.619  -0.606  -0.564
9     A        -1.179  -1.171  -1.147  -1.116  -1.112  -1.064  -0.969  -0.958  -0.917
10    I        -1.179  -1.171  -1.147  -1.281  -1.288  -1.230  -0.969  -0.958  -0.917
11    S        -0.384  -0.389  -0.399  -0.419  -0.424  -0.440  -0.444  -0.449  -0.455
12    P         0.710   0.706   0.635   0.846   0.839   0.732   0.608   0.601   0.471
13    D         0.710   0.706   0.635   0.766   0.756   0.635   0.608   0.601   0.471
14    I        -0.384  -0.422  -0.423  -0.350  -0.415  -0.414  -0.444  -0.491  -0.486
15    T        -0.384  -0.422  -0.423  -0.262  -0.335  -0.337  -0.444  -0.491  -0.486
16    L        -0.384  -0.360  -0.390  -0.431  -0.388  -0.459  -0.444  -0.409  -0.443
17    F        -0.384  -0.422  -0.423  -0.512  -0.548  -0.541  -0.444  -0.491  -0.486
18    N         0.410   0.418   0.452   0.308   0.323   0.374   0.082   0.093   0.143
19    K        -0.384  -0.394  -0.398  -0.271  -0.294  -0.285  -0.444  -0.455  -0.454
20    T        -1.179  -1.171  -1.147  -1.330  -1.306  -1.279  -0.969  -0.958  -0.917
21    L        -0.384  -0.422  -0.423  -0.501  -0.570  -0.588  -0.444  -0.491  -0.486
22    T        -0.384  -0.364  -0.392  -0.321  -0.293  -0.330  -0.444  -0.415  -0.446
23    F         0.710   0.658   0.626   0.901   0.828   0.786   0.608   0.520   0.455
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    E        -0.384  -0.364  -0.392  -0.330  -0.306  -0.341  -0.444  -0.415  -0.446
27    I        -1.179  -1.171  -1.147  -1.052  -1.047  -0.999  -0.969  -0.958  -0.917
28    S         0.710   0.753   0.653   0.641   0.715   0.543   0.608   0.679   0.502
29    Q        -0.384  -0.360  -0.390  -0.368  -0.326  -0.378  -0.444  -0.409  -0.443
30    N        -1.179  -1.171  -1.147  -1.081  -1.067  -1.028  -0.969  -0.958  -0.917
31    T        -0.384  -0.422  -0.423  -0.291  -0.350  -0.345  -0.444  -0.491  -0.486
32    R        -1.179  -1.171  -1.147  -1.062  -1.053  -1.009  -0.969  -0.958  -0.917
33    E        -1.179  -1.171  -1.147  -1.078  -1.054  -1.025  -0.969  -0.958  -0.917
34    A        -0.384  -0.422  -0.423  -0.177  -0.236  -0.225  -0.444  -0.491  -0.486
35    V        -0.384  -0.328  -0.392  -0.475  -0.375  -0.499  -0.444  -0.366  -0.445
36    I         0.710   0.753   0.653   0.579   0.652   0.464   0.608   0.679   0.502
37    Y        -0.384  -0.394  -0.398  -0.411  -0.418  -0.448  -0.444  -0.455  -0.454
38    I         0.710   0.658   0.626   0.747   0.674   0.633   0.608   0.520   0.455
39    H         1.999   2.011   2.050   2.168   2.189   2.249   2.186   2.203   2.261
40    G         1.999   2.011   2.050   2.076   2.093   2.156   2.186   2.203   2.261
41    G         1.999   2.011   2.050   2.076   2.093   2.156   2.186   2.203   2.261
42    A         1.999   2.011   2.050   2.093   2.107   2.173   2.186   2.203   2.261
43    W         1.999   2.011   2.050   2.297   2.314   2.379   2.186   2.203   2.261
44    N        -0.384  -0.422  -0.423  -0.216  -0.284  -0.293  -0.444  -0.491  -0.486
45    D         1.999   2.011   2.050   1.947   1.965   2.026   2.186   2.203   2.261
46    P         0.710   0.658   0.626   0.879   0.793   0.744   0.608   0.520   0.455
47    E        -1.179  -1.171  -1.147  -1.152  -1.138  -1.100  -0.969  -0.958  -0.917
48    N         0.710   0.658   0.626   0.786   0.713   0.658   0.608   0.520   0.455
49    T         1.999   2.011   2.050   2.093   2.109   2.173   2.186   2.203   2.261
50    P        -1.179  -1.171  -1.147  -0.971  -0.968  -0.917  -0.969  -0.958  -0.917
51    N        -0.384  -0.389  -0.399  -0.406  -0.415  -0.437  -0.444  -0.449  -0.455
52    D         0.710   0.761   0.654   0.669   0.745   0.579   0.608   0.691   0.503
53    F        -0.384  -0.389  -0.399  -0.199  -0.215  -0.216  -0.444  -0.449  -0.455
54    N        -1.179  -1.171  -1.147  -1.052  -1.054  -0.999  -0.969  -0.958  -0.917
55    Q        -1.179  -1.171  -1.147  -1.030  -1.025  -0.977  -0.969  -0.958  -0.917
56    L        -0.384  -0.328  -0.392  -0.528  -0.447  -0.525  -0.444  -0.366  -0.445
57    A        -1.179  -1.171  -1.147  -1.149  -1.114  -1.097  -0.969  -0.958  -0.917
58    N        -1.179  -1.171  -1.147  -1.123  -1.109  -1.070  -0.969  -0.958  -0.917
59    T        -0.519  -0.514  -0.484  -0.453  -0.449  -0.394  -0.619  -0.610  -0.564
60    I         0.540   0.528   0.535   0.396   0.371   0.379   0.316   0.293   0.295
61    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    T        -0.519  -0.514  -0.484  -0.542  -0.538  -0.485  -0.619  -0.610  -0.564
66    E        -1.179  -1.171  -1.147  -1.159  -1.159  -1.107  -0.969  -0.958  -0.917
67    S        -1.179  -1.171  -1.147  -1.030  -1.028  -0.977  -0.969  -0.958  -0.917
68    T        -0.384  -0.364  -0.392  -0.343  -0.311  -0.355  -0.444  -0.415  -0.446
69    V        -0.384  -0.328  -0.392  -0.323  -0.240  -0.332  -0.444  -0.366  -0.445
70    C        -0.384  -0.422  -0.423  -0.119  -0.160  -0.146  -0.444  -0.491  -0.486
71    Q        -0.384  -0.422  -0.423  -0.559  -0.604  -0.596  -0.444  -0.491  -0.486
72    Y        -0.384  -0.422  -0.423  -0.383  -0.445  -0.436  -0.444  -0.491  -0.486
73    S        -0.384  -0.328  -0.392  -0.396  -0.308  -0.403  -0.444  -0.366  -0.445
74    I         0.710   0.753   0.653   0.747   0.808   0.672   0.608   0.679   0.502
75    E         0.410   0.421   0.455   0.236   0.254   0.306   0.082   0.100   0.148
76    Y         1.999   2.011   2.050   2.093   2.113   2.173   2.186   2.203   2.261
77    R         1.999   2.011   2.050   2.213   2.234   2.294   2.186   2.203   2.261
78    L         1.999   2.011   2.050   1.736   1.762   1.813   2.186   2.203   2.261
79    S         0.710   0.658   0.626   0.688   0.614   0.559   0.608   0.520   0.455
80    P         1.999   2.011   2.050   2.145   2.160   2.226   2.186   2.203   2.261
81    E         1.999   2.011   2.050   2.035   2.052   2.115   2.186   2.203   2.261
82    I         0.410   0.418   0.452   0.167   0.178   0.232   0.082   0.094   0.143
83    T        -0.384  -0.422  -0.423  -0.386  -0.455  -0.453  -0.444  -0.491  -0.486
84    N        -0.384  -0.422  -0.423  -0.233  -0.297  -0.303  -0.444  -0.491  -0.486
85    P         0.710   0.658   0.626   0.857   0.767   0.715   0.608   0.520   0.455
86    R        -1.179  -1.171  -1.147  -0.935  -0.924  -0.880  -0.969  -0.958  -0.917
87    N        -0.384  -0.422  -0.423  -0.223  -0.285  -0.292  -0.444  -0.491  -0.486
88    L         0.710   0.658   0.626   0.484   0.412   0.359   0.608   0.520   0.455
89    Y        -1.179  -1.171  -1.147  -0.965  -0.963  -0.911  -0.969  -0.958  -0.917
90    D         1.999   2.011   2.050   1.947   1.965   2.026   2.186   2.203   2.261
91    A        -0.384  -0.360  -0.390  -0.383  -0.346  -0.394  -0.444  -0.409  -0.443
92    V        -0.384  -0.422  -0.423  -0.602  -0.648  -0.646  -0.444  -0.491  -0.486
93    S        -1.179  -1.171  -1.147  -1.046  -1.038  -0.993  -0.969  -0.958  -0.917
94    N        -0.384  -0.364  -0.392  -0.296  -0.270  -0.310  -0.444  -0.415  -0.446
95    I         0.410   0.421   0.455  -0.046  -0.015   0.031   0.082   0.100   0.148
96    T        -1.179  -1.171  -1.147  -0.922  -0.924  -0.868  -0.969  -0.958  -0.917
97    R        -0.384  -0.422  -0.423  -0.269  -0.332  -0.332  -0.444  -0.491  -0.486
98    L        -0.384  -0.389  -0.399  -0.668  -0.675  -0.689  -0.444  -0.449  -0.455
99    V        -0.384  -0.389  -0.399  -0.350  -0.361  -0.374  -0.444  -0.449  -0.455
100   K        -0.384  -0.422  -0.423  -0.321  -0.395  -0.399  -0.444  -0.491  -0.486
101   E        -0.384  -0.422  -0.423  -0.368  -0.433  -0.434  -0.444  -0.491  -0.486
102   K        -0.384  -0.360  -0.390  -0.291  -0.255  -0.301  -0.444  -0.409  -0.443
103   G        -0.384  -0.422  -0.423  -0.373  -0.433  -0.423  -0.444  -0.491  -0.486
104   L        -1.179  -1.171  -1.147  -1.284  -1.272  -1.233  -0.969  -0.958  -0.917
105   T        -1.179  -1.171  -1.147  -1.008  -0.997  -0.955  -0.969  -0.958  -0.917
106   N        -1.179  -1.171  -1.147  -0.990  -0.980  -0.936  -0.969  -0.958  -0.917
107   I         0.710   0.658   0.626   0.762   0.690   0.652   0.608   0.520   0.455
108   N        -0.384  -0.364  -0.392  -0.439  -0.398  -0.467  -0.444  -0.415  -0.446
109   M        -0.384  -0.328  -0.392  -0.333  -0.220  -0.368  -0.444  -0.366  -0.445
110   V        -1.179  -1.171  -1.147  -1.284  -1.271  -1.233  -0.969  -0.958  -0.917
111   G         1.999   2.011   2.050   2.076   2.093   2.156   2.186   2.203   2.261
112   H         1.999   2.011   2.050   2.168   2.189   2.249   2.186   2.203   2.261
113   S         1.999   2.011   2.050   1.947   1.974   2.026   2.186   2.203   2.261
114   V         0.710   0.658   0.626   0.762   0.679   0.630   0.608   0.520   0.455
115   G         1.999   2.011   2.050   2.076   2.093   2.156   2.186   2.203   2.261
116   A         1.999   2.011   2.050   2.093   2.107   2.173   2.186   2.203   2.261
117   T         0.710   0.658   0.626   0.831   0.748   0.698   0.608   0.520   0.455
118   F        -1.179  -1.171  -1.147  -1.027  -1.004  -0.974  -0.969  -0.958  -0.917
119   I        -0.384  -0.394  -0.398  -0.375  -0.399  -0.391  -0.444  -0.455  -0.454
120   W         0.710   0.706   0.635   0.555   0.557   0.464   0.608   0.601   0.471
121   Q         0.710   0.658   0.626   0.846   0.762   0.705   0.608   0.520   0.455
122   I         0.710   0.706   0.635   0.435   0.435   0.311   0.608   0.601   0.471
123   L         1.999   2.011   2.050   1.647   1.665   1.723   2.186   2.203   2.261
124   A        -0.519  -0.511  -0.484  -0.473  -0.453  -0.415  -0.619  -0.606  -0.564
125   A         0.540   0.507   0.513   0.578   0.520   0.528   0.316   0.255   0.255
126   L        -0.519  -0.511  -0.484  -0.746  -0.759  -0.691  -0.619  -0.606  -0.564
127   K         0.540   0.567   0.535   0.547   0.591   0.535   0.316   0.362   0.295
128   D         0.540   0.507   0.513   0.372   0.310   0.312   0.316   0.255   0.255
129   P        -0.519  -0.511  -0.484  -0.776  -0.743  -0.721  -0.619  -0.606  -0.564
130   Q        -0.519  -0.511  -0.484  -0.473  -0.457  -0.415  -0.619  -0.606  -0.564
131   E        -0.519  -0.511  -0.484  -0.574  -0.563  -0.516  -0.619  -0.606  -0.564
132   K         0.540   0.507   0.513   0.558   0.498   0.501   0.316   0.255   0.255
133   M        -0.519  -0.511  -0.484  -0.644  -0.614  -0.588  -0.619  -0.606  -0.564
134   S        -0.519  -0.511  -0.484  -0.569  -0.565  -0.512  -0.619  -0.606  -0.564
135   E        -0.519  -0.511  -0.484  -0.541  -0.527  -0.484  -0.619  -0.606  -0.564
136   A        -0.519  -0.511  -0.484  -0.707  -0.682  -0.651  -0.619  -0.606  -0.564
137   Q        -0.519  -0.511  -0.484  -0.450  -0.434  -0.392  -0.619  -0.606  -0.564
138   L        -0.519  -0.511  -0.484  -0.796  -0.808  -0.741  -0.619  -0.606  -0.564
139   Q         0.540   0.507   0.513   0.457   0.403   0.410   0.316   0.255   0.255
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   M        -0.384  -0.364  -0.392  -0.343  -0.311  -0.346  -0.444  -0.415  -0.446
146   L        -0.384  -0.394  -0.398  -0.546  -0.560  -0.552  -0.444  -0.455  -0.454
147   G        -1.179  -1.171  -1.147  -1.097  -1.088  -1.044  -0.969  -0.958  -0.917
148   L        -0.384  -0.360  -0.390  -0.530  -0.486  -0.556  -0.444  -0.409  -0.443
149   L        -0.384  -0.394  -0.398  -0.602  -0.617  -0.614  -0.444  -0.455  -0.454
150   Q        -0.384  -0.422  -0.423  -0.378  -0.437  -0.429  -0.444  -0.491  -0.486
151   -        -0.519  -0.508  -0.484  -0.738  -0.703  -0.682  -0.619  -0.602  -0.564
152   -        -0.519  -0.508  -0.484  -0.668  -0.632  -0.612  -0.619  -0.602  -0.564
153   -        -0.519  -0.508  -0.484  -0.542  -0.528  -0.484  -0.619  -0.602  -0.564
154   -        -0.519  -0.508  -0.484  -0.542  -0.543  -0.484  -0.619  -0.602  -0.564
155   -        -0.519  -0.508  -0.484  -0.643  -0.608  -0.587  -0.619  -0.602  -0.564
156   -        -0.519  -0.508  -0.484  -0.561  -0.544  -0.504  -0.619  -0.602  -0.564
157   -         0.540   0.578   0.542   0.484   0.552   0.478   0.316   0.381   0.306
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   I         0.540   0.507   0.513   0.075   0.017   0.025   0.316   0.255   0.255
162   V        -0.519  -0.511  -0.484  -0.688  -0.675  -0.631  -0.619  -0.606  -0.564
163   K        -0.519  -0.511  -0.484  -0.649  -0.631  -0.593  -0.619  -0.606  -0.564
164   R        -0.519  -0.511  -0.484  -0.428  -0.411  -0.369  -0.619  -0.606  -0.564
165   V        -0.384  -0.394  -0.398  -0.383  -0.411  -0.408  -0.444  -0.455  -0.454
166   F        -0.384  -0.364  -0.392  -0.311  -0.286  -0.312  -0.444  -0.415  -0.446
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   L         0.410   0.421   0.455   0.066   0.074   0.121   0.082   0.100   0.148
177   L        -0.384  -0.394  -0.398  -0.704  -0.713  -0.727  -0.444  -0.455  -0.454
178   D         0.710   0.658   0.626   0.669   0.586   0.534   0.608   0.520   0.455
179   G         1.999   2.011   2.050   2.076   2.093   2.156   2.186   2.203   2.261
180   I         1.999   2.011   2.050   1.953   1.971   2.032   2.186   2.203   2.261
181   Y         1.999   2.011   2.050   2.093   2.113   2.173   2.186   2.203   2.261
182   S         0.710   0.706   0.635   0.641   0.635   0.512   0.608   0.601   0.471
183   L        -0.384  -0.328  -0.392  -0.668  -0.578  -0.678  -0.444  -0.366  -0.445
184   K        -1.179  -1.171  -1.147  -0.980  -0.966  -0.927  -0.969  -0.958  -0.917
185   E        -0.384  -0.394  -0.398  -0.296  -0.317  -0.313  -0.444  -0.455  -0.454
186   L         1.999   2.011   2.050   1.736   1.762   1.813   2.186   2.203   2.261
187   L        -0.384  -0.394  -0.398  -0.668  -0.677  -0.687  -0.444  -0.455  -0.454
188   V        -1.179  -1.171  -1.147  -1.209  -1.201  -1.157  -0.969  -0.958  -0.917
189   E         0.710   0.658   0.626   0.726   0.638   0.580   0.608   0.520   0.455
190   Y         0.710   0.658   0.626   0.853   0.777   0.727   0.608   0.520   0.455
191   P         0.710   0.753   0.653   0.873   0.935   0.782   0.608   0.679   0.502
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   E        -1.179  -1.171  -1.147  -1.052  -1.046  -0.999  -0.969  -0.958  -0.917
194   Y         1.999   2.011   2.050   2.093   2.113   2.173   2.186   2.203   2.261
195   D        -1.179  -1.171  -1.147  -1.162  -1.161  -1.110  -0.969  -0.958  -0.917
196   C        -0.384  -0.422  -0.423  -0.276  -0.321  -0.311  -0.444  -0.491  -0.486
197   F         1.999   2.011   2.050   2.099   2.120   2.179   2.186   2.203   2.261
198   T         0.410   0.421   0.455   0.270   0.287   0.343   0.082   0.100   0.148
199   R        -0.384  -0.360  -0.390  -0.323  -0.277  -0.330  -0.444  -0.409  -0.443
200   L        -1.179  -1.171  -1.147  -1.250  -1.231  -1.198  -0.969  -0.958  -0.917
201   A         1.999   2.011   2.050   2.093   2.107   2.173   2.186   2.203   2.261
202   F         0.710   0.658   0.626   0.901   0.828   0.786   0.608   0.520   0.455
203   P        -1.179  -1.171  -1.147  -1.068  -1.053  -1.015  -0.969  -0.958  -0.917
204   D        -0.384  -0.422  -0.423  -0.478  -0.537  -0.545  -0.444  -0.491  -0.486
205   G        -1.179  -1.171  -1.147  -1.062  -1.063  -1.009  -0.969  -0.958  -0.917
206   I        -0.384  -0.364  -0.392  -0.408  -0.383  -0.426  -0.444  -0.415  -0.446
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   Q         1.999   2.011   2.050   2.123   2.143   2.204   2.186   2.203   2.261
214   M         0.540   0.507   0.513   0.223   0.180   0.201   0.316   0.255   0.255
215   Y         0.540   0.507   0.513   0.415   0.359   0.366   0.316   0.255   0.255
216   E         0.540   0.507   0.513   0.394   0.335   0.341   0.316   0.255   0.255
217   E        -0.384  -0.364  -0.392  -0.350  -0.320  -0.370  -0.444  -0.415  -0.446
218   E        -1.179  -1.171  -1.147  -1.071  -1.068  -1.018  -0.969  -0.958  -0.917
219   P        -1.179  -1.171  -1.147  -0.901  -0.883  -0.847  -0.969  -0.958  -0.917
220   S         0.410   0.418   0.452   0.106   0.121   0.170   0.082   0.094   0.143
221   R        -1.179  -1.171  -1.147  -1.166  -1.140  -1.113  -0.969  -0.958  -0.917
222   V        -1.179  -1.171  -1.147  -1.129  -1.122  -1.077  -0.969  -0.958  -0.917
223   M        -0.384  -0.360  -0.390  -0.470  -0.413  -0.481  -0.444  -0.409  -0.443
224   P         1.999   2.011   2.050   2.145   2.160   2.226   2.186   2.203   2.261
225   Y        -0.384  -0.422  -0.423  -0.408  -0.486  -0.495  -0.444  -0.491  -0.486
226   V        -0.384  -0.422  -0.423  -0.575  -0.645  -0.659  -0.444  -0.491  -0.486
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   K        -0.519  -0.514  -0.484  -0.523  -0.513  -0.466  -0.619  -0.610  -0.564
229   K        -0.519  -0.514  -0.484  -0.519  -0.511  -0.461  -0.619  -0.610  -0.564
230   A         0.540   0.557   0.542   0.580   0.604   0.582   0.316   0.344   0.307
231   L         0.710   0.658   0.626   0.573   0.516   0.474   0.608   0.520   0.455
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   S         0.540   0.507   0.513   0.429   0.364   0.363   0.316   0.255   0.255
235   R         0.540   0.567   0.535   0.582   0.630   0.556   0.316   0.362   0.295
236   F        -1.179  -1.171  -1.147  -1.008  -0.994  -0.955  -0.969  -0.958  -0.917
237   S        -1.179  -1.171  -1.147  -1.202  -1.191  -1.150  -0.969  -0.958  -0.917
238   I        -0.384  -0.328  -0.392  -0.538  -0.442  -0.560  -0.444  -0.366  -0.445
239   D        -0.384  -0.360  -0.390  -0.406  -0.366  -0.420  -0.444  -0.409  -0.443
240   M        -1.179  -1.171  -1.147  -1.068  -1.042  -1.015  -0.969  -0.958  -0.917
241   H        -1.179  -1.171  -1.147  -1.159  -1.132  -1.107  -0.969  -0.958  -0.917
242   L         0.710   0.706   0.635   0.579   0.571   0.431   0.608   0.601   0.471
243   V        -0.384  -0.328  -0.392  -0.475  -0.375  -0.499  -0.444  -0.366  -0.445
244   H         0.410   0.421   0.455   0.402   0.424   0.475   0.082   0.100   0.148
245   S         1.999   2.011   2.050   1.947   1.974   2.026   2.186   2.203   2.261
246   Y        -1.179  -1.171  -1.147  -1.281  -1.259  -1.230  -0.969  -0.958  -0.917
247   S        -1.179  -1.171  -1.147  -1.199  -1.195  -1.147  -0.969  -0.958  -0.917
248   D         1.999   2.011   2.050   1.947   1.965   2.026   2.186   2.203   2.261
249   E         0.710   0.761   0.654   0.726   0.804   0.628   0.608   0.691   0.503
250   L         1.999   2.011   2.050   1.736   1.762   1.813   2.186   2.203   2.261
251   L         0.710   0.658   0.626   0.460   0.387   0.328   0.608   0.520   0.455
252   T        -0.384  -0.422  -0.423  -0.365  -0.418  -0.414  -0.444  -0.491  -0.486
253   L        -0.384  -0.422  -0.423  -0.271  -0.341  -0.366  -0.444  -0.491  -0.486
254   R        -0.384  -0.389  -0.399  -0.252  -0.270  -0.289  -0.444  -0.449  -0.455
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   Q         1.999   2.011   2.050   2.133   2.155   2.214   2.186   2.203   2.261
257   T         0.710   0.658   0.626   0.846   0.763   0.717   0.608   0.520   0.455
258   N        -0.384  -0.389  -0.399  -0.264  -0.270  -0.280  -0.444  -0.449  -0.455
259   C         0.710   0.706   0.635   0.573   0.578   0.486   0.608   0.601   0.471
260   L         0.710   0.753   0.653   0.486   0.556   0.402   0.608   0.679   0.502
261   I         0.710   0.658   0.626   0.694   0.612   0.564   0.608   0.520   0.455
262   S        -1.179  -1.171  -1.147  -1.202  -1.191  -1.150  -0.969  -0.958  -0.917
263   C        -0.384  -0.422  -0.423  -0.185  -0.245  -0.233  -0.444  -0.491  -0.486
264   L         0.710   0.658   0.626   0.555   0.493   0.451   0.608   0.520   0.455
265   Q        -1.179  -1.171  -1.147  -1.065  -1.053  -1.012  -0.969  -0.958  -0.917
266   D        -0.384  -0.360  -0.390  -0.353  -0.307  -0.372  -0.444  -0.409  -0.443
267   Y        -0.384  -0.422  -0.423  -0.306  -0.366  -0.360  -0.444  -0.491  -0.486
268   Q        -0.384  -0.422  -0.423  -0.303  -0.361  -0.359  -0.444  -0.491  -0.486
269   L        -0.384  -0.389  -0.399  -0.583  -0.589  -0.595  -0.444  -0.449  -0.455
270   S        -1.179  -1.171  -1.147  -1.062  -1.047  -1.009  -0.969  -0.958  -0.917
271   F         1.999   2.011   2.050   2.099   2.120   2.179   2.186   2.203   2.261
272   K        -0.384  -0.389  -0.399  -0.386  -0.409  -0.413  -0.444  -0.449  -0.455
273   L        -0.384  -0.394  -0.398  -0.543  -0.553  -0.549  -0.444  -0.455  -0.454
274   Y        -1.179  -1.171  -1.147  -0.959  -0.955  -0.905  -0.969  -0.958  -0.917
275   L         0.710   0.706   0.635   0.648   0.641   0.500   0.608   0.601   0.471
276   D        -0.384  -0.422  -0.423  -0.401  -0.476  -0.481  -0.444  -0.491  -0.486
277   D        -1.179  -1.171  -1.147  -1.046  -1.027  -0.993  -0.969  -0.958  -0.917
278   L        -0.384  -0.422  -0.423  -0.242  -0.319  -0.341  -0.444  -0.491  -0.486
279   G         0.710   0.658   0.626   0.700   0.606   0.532   0.608   0.520   0.455
280   L        -0.384  -0.364  -0.392  -0.483  -0.457  -0.508  -0.444  -0.415  -0.446
281   H         1.999   2.011   2.050   2.168   2.189   2.249   2.186   2.203   2.261
282   N         0.410   0.421   0.455   0.236   0.255   0.306   0.082   0.100   0.148
283   D        -0.384  -0.328  -0.392  -0.381  -0.299  -0.387  -0.444  -0.366  -0.445
284   V         0.710   0.761   0.654   0.717   0.795   0.620   0.608   0.691   0.503
285   Y         0.410   0.418   0.452   0.324   0.336   0.390   0.082   0.093   0.143
286   K        -1.179  -1.171  -1.147  -1.027  -1.032  -0.974  -0.969  -0.958  -0.917
287   N        -1.179  -1.171  -1.147  -1.078  -1.071  -1.025  -0.969  -0.958  -0.917
288   G        -1.179  -1.171  -1.147  -1.091  -1.085  -1.038  -0.969  -0.958  -0.917
289   K        -1.179  -1.171  -1.147  -1.052  -1.050  -0.999  -0.969  -0.958  -0.917
290   V        -0.384  -0.389  -0.399  -0.345  -0.355  -0.368  -0.444  -0.449  -0.455
291   A         0.710   0.761   0.654   0.785   0.859   0.686   0.608   0.691   0.503
292   K        -0.384  -0.328  -0.392  -0.378  -0.290  -0.392  -0.444  -0.366  -0.445
293   Y        -0.384  -0.360  -0.390  -0.381  -0.345  -0.384  -0.444  -0.409  -0.443
294   I        -1.179  -1.171  -1.147  -1.166  -1.151  -1.113  -0.969  -0.958  -0.917
295   F        -1.179  -1.171  -1.147  -1.202  -1.179  -1.150  -0.969  -0.958  -0.917
296   D        -0.384  -0.389  -0.399  -0.439  -0.451  -0.462  -0.444  -0.449  -0.455
297   N        -1.179  -1.171  -1.147  -1.199  -1.186  -1.147  -0.969  -0.958  -0.917
298   I         0.710   0.761   0.654   0.711   0.783   0.629   0.608   0.691   0.503
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q04066
Output conservation file - output/Q04066
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
