1     M         2.267   2.353   2.473   2.614   2.724   2.923   2.564   2.704   2.927
2     T        -1.142  -1.090  -1.133  -0.919  -0.834  -0.896  -0.878  -0.824  -0.825
3     T        -0.924  -0.740  -0.819  -1.321  -0.991  -1.163  -0.863  -0.670  -0.723
4     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     P        -0.273  -0.233  -0.286  -0.171  -0.108  -0.235  -0.373  -0.325  -0.393
6     S        -0.924  -0.933  -0.857  -0.899  -0.903  -0.809  -0.863  -0.860  -0.760
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    V        -1.023  -0.932  -0.867  -0.757  -0.593  -0.520  -0.960  -0.856  -0.769
20    K        -0.749  -0.881  -0.831  -0.995  -1.128  -1.029  -0.673  -0.801  -0.735
21    L         1.428   1.413   1.306   1.534   1.527   1.368   1.485   1.440   1.193
22    K         1.428   1.626   1.341   1.116   1.365   1.019   1.485   1.807   1.265
23    S        -0.344  -0.313  -0.267  -0.227  -0.089  -0.060  -0.493  -0.426  -0.372
24    A        -0.092  -0.234  -0.268  -0.165  -0.421  -0.513  -0.133  -0.317  -0.369
25    K         0.639   0.544   0.406   0.452   0.358   0.209   0.586   0.432   0.186
26    D         1.496   1.380   1.361   1.636   1.469   1.391   1.600   1.380   1.304
27    S        -0.213  -0.259  -0.272  -0.108  -0.116  -0.148  -0.327  -0.377  -0.386
28    L         0.072  -0.112  -0.203   0.195  -0.123  -0.310   0.086  -0.159  -0.283
29    V         0.763   0.725   0.538   1.078   1.017   0.756   0.774   0.714   0.399
30    S         0.275   0.284   0.321   0.015   0.038   0.093  -0.052  -0.040   0.021
31    S        -0.788  -0.875  -0.771  -0.872  -1.008  -0.859  -0.740  -0.804  -0.682
32    L         0.072  -0.112  -0.203   0.378   0.149   0.029   0.086  -0.159  -0.283
33    F         0.763   0.602   0.507   1.178   0.951   0.754   0.774   0.519   0.349
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    E         0.763   0.602   0.507   0.631   0.360   0.215   0.774   0.519   0.349
38    L         1.496   1.380   1.361   1.617   1.474   1.446   1.600   1.380   1.304
39    S         0.072  -0.112  -0.203   0.218  -0.006  -0.208   0.086  -0.159  -0.283
40    K         0.072  -0.112  -0.203  -0.123  -0.335  -0.510   0.086  -0.159  -0.283
41    A         1.117   1.225   1.154   0.893   1.049   0.891   0.912   1.086   0.877
42    A         2.267   2.353   2.473   2.140   2.235   2.439   2.564   2.704   2.927
43    N        -0.300  -0.345  -0.281  -0.191  -0.240  -0.177  -0.465  -0.481  -0.396
44    Q        -0.921  -0.926  -0.812  -0.609  -0.588  -0.422  -0.878  -0.852  -0.721
45    T         0.275   0.298   0.360   0.115   0.162   0.267  -0.052   0.030   0.099
46    A         1.496   1.513   1.399   1.452   1.469   1.319   1.600   1.617   1.379
47    S        -1.142  -1.272  -1.214  -0.767  -0.862  -0.784  -0.878  -0.980  -0.897
48    S        -0.213  -0.009  -0.213  -0.174   0.030  -0.135  -0.327  -0.130  -0.319
49    I        -0.213  -0.101  -0.211  -0.043   0.085  -0.063  -0.327  -0.206  -0.314
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    V         0.072  -0.003  -0.132   0.505   0.403   0.244   0.086  -0.009  -0.189
52    D         0.426   0.428   0.374   0.436   0.413   0.300   0.223   0.208   0.113
53    F         0.763   0.607   0.500   1.231   1.033   0.847   0.774   0.525   0.339
54    Y         0.072  -0.112  -0.203   0.712   0.498   0.405   0.086  -0.159  -0.283
55    N        -1.276  -1.250  -1.208  -1.158  -1.155  -1.017  -1.016  -0.969  -0.894
56    A        -1.276  -1.141  -1.165  -1.187  -0.972  -1.011  -1.016  -0.879  -0.860
57    I        -1.142  -1.272  -1.214  -0.714  -0.915  -0.865  -0.878  -0.980  -0.897
58    G        -0.788  -0.888  -0.816  -0.552  -0.701  -0.623  -0.740  -0.819  -0.723
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    D        -0.344  -0.266  -0.300  -0.252  -0.115  -0.192  -0.493  -0.409  -0.423
67    D        -0.433  -0.421  -0.357  -0.470  -0.441  -0.372  -0.603  -0.582  -0.490
68    E        -0.300  -0.368  -0.260  -0.461  -0.494  -0.349  -0.465  -0.514  -0.379
69    E        -0.788  -0.887  -0.798  -0.668  -0.699  -0.531  -0.740  -0.817  -0.706
70    E        -0.567  -0.722  -0.732  -0.634  -0.876  -0.901  -0.465  -0.633  -0.630
71    K        -1.142  -1.101  -1.137  -0.909  -0.823  -0.972  -0.878  -0.824  -0.829
72    I        -0.788  -0.818  -0.761  -0.523  -0.577  -0.494  -0.740  -0.754  -0.672
73    E         0.763   0.607   0.500   0.596   0.354   0.132   0.774   0.525   0.339
74    A         0.072  -0.076  -0.161   0.187  -0.015  -0.130   0.086  -0.114  -0.228
75    F         0.275   0.202   0.309   0.403   0.302   0.455  -0.052  -0.138   0.002
76    T        -0.788  -0.873  -0.802  -0.719  -0.865  -0.772  -0.740  -0.806  -0.710
77    T        -1.306  -1.306  -1.233  -1.177  -1.235  -1.113  -1.032  -1.014  -0.914
78    L         1.428   1.452   1.360   1.525   1.563   1.444   1.485   1.509   1.302
79    T        -0.344  -0.411  -0.340  -0.317  -0.403  -0.354  -0.493  -0.562  -0.467
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    E         0.763   0.639   0.510   0.596   0.376   0.150   0.774   0.573   0.354
82    S        -0.300  -0.287  -0.254  -0.583  -0.536  -0.527  -0.465  -0.432  -0.375
83    L         0.763   0.607   0.500   1.043   0.870   0.755   0.774   0.525   0.339
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    Q         0.966   0.981   1.070   0.991   0.971   1.108   0.606   0.587   0.695
86    T        -0.273  -0.278  -0.309  -0.211  -0.194  -0.344  -0.373  -0.396  -0.422
87    L        -0.273  -0.423  -0.363  -0.078  -0.266  -0.170  -0.373  -0.564  -0.490
88    T         0.199   0.118   0.234   0.080  -0.086   0.077  -0.128  -0.243  -0.096
89    S        -0.213  -0.342  -0.284  -0.124  -0.245  -0.187  -0.327  -0.476  -0.400
90    G        -1.306  -1.242  -1.198  -1.235  -1.137  -1.075  -1.032  -0.964  -0.884
91    V        -0.749  -0.579  -0.697  -0.577  -0.309  -0.533  -0.673  -0.479  -0.592
92    N         0.639   0.587   0.485   0.930   0.874   0.705   0.586   0.499   0.314
93    H        -0.901  -0.841  -0.808  -0.732  -0.739  -0.584  -0.853  -0.778  -0.714
94    L        -0.092  -0.179  -0.238   0.088  -0.026  -0.129  -0.133  -0.244  -0.330
95    H        -0.901  -0.795  -0.798  -0.538  -0.429  -0.398  -0.853  -0.724  -0.704
96    G        -0.092  -0.014  -0.154   0.291   0.411   0.185  -0.133  -0.036  -0.218
97    I        -0.344  -0.378  -0.336  -0.336  -0.489  -0.411  -0.493  -0.524  -0.463
98    S        -0.092  -0.267  -0.254   0.110  -0.086  -0.096  -0.133  -0.364  -0.351
99    S        -0.497  -0.442  -0.349  -0.718  -0.617  -0.488  -0.673  -0.594  -0.480
100   E        -0.092  -0.126  -0.195  -0.189  -0.250  -0.332  -0.133  -0.193  -0.273
101   L         1.428   1.437   1.358   1.478   1.492   1.358   1.485   1.483   1.299
102   V        -0.901  -0.850  -0.807  -0.807  -0.773  -0.670  -0.853  -0.785  -0.712
103   N         0.639   0.587   0.485   0.930   0.874   0.705   0.586   0.499   0.314
104   P         0.871   0.920   1.038   0.806   0.873   1.061   0.406   0.457   0.625
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   I        -0.788  -0.633  -0.728  -0.430  -0.218  -0.286  -0.740  -0.541  -0.628
116   D        -0.901  -0.905  -0.806  -0.930  -0.945  -0.793  -0.853  -0.829  -0.711
117   D        -0.749  -0.768  -0.771  -0.588  -0.562  -0.671  -0.673  -0.691  -0.672
118   D        -0.924  -0.919  -0.853  -0.811  -0.780  -0.720  -0.863  -0.849  -0.757
119   K        -0.451  -0.393  -0.364  -0.746  -0.532  -0.556  -0.618  -0.540  -0.493
120   D        -0.924  -0.743  -0.825  -0.807  -0.481  -0.695  -0.863  -0.675  -0.729
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   A        -0.921  -0.825  -0.804  -1.097  -0.969  -0.897  -0.878  -0.774  -0.716
134   I        -1.630  -1.508  -1.514  -1.570  -1.437  -1.380  -1.153  -1.041  -0.996
135   I        -0.921  -0.873  -0.810  -0.877  -0.841  -0.696  -0.878  -0.814  -0.720
136   A        -1.276  -1.126  -1.170  -1.006  -0.796  -0.843  -1.016  -0.875  -0.864
137   A        -0.788  -0.789  -0.785  -0.660  -0.660  -0.588  -0.740  -0.736  -0.694
138   P        -0.788  -0.643  -0.732  -0.923  -0.745  -0.896  -0.740  -0.601  -0.643
139   V        -0.788  -0.487  -0.728  -0.818  -0.468  -0.704  -0.740  -0.437  -0.636
140   K         0.426   0.398   0.376   0.095   0.096   0.039   0.223   0.167   0.121
141   A        -0.213   0.036  -0.191  -0.489  -0.164  -0.439  -0.327  -0.052  -0.283
142   V        -0.788  -0.712  -0.743  -1.054  -0.977  -1.004  -0.740  -0.634  -0.644
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   R         0.914   0.964   1.045   0.417   0.497   0.626   0.499   0.550   0.640
160   R         0.914   0.994   1.068   0.417   0.538   0.642   0.499   0.616   0.692
161   K         2.267   2.353   2.473   1.870   2.006   2.163   2.564   2.704   2.927
162   I        -0.788  -0.602  -0.717  -0.387  -0.118  -0.251  -0.740  -0.507  -0.616
163   E        -0.213  -0.163  -0.224  -0.303  -0.259  -0.280  -0.327  -0.267  -0.330
164   R        -0.433  -0.487  -0.369  -0.450  -0.526  -0.365  -0.603  -0.643  -0.502
165   D         2.267   2.353   2.473   2.370   2.496   2.674   2.564   2.704   2.927
166   P         2.267   2.353   2.473   2.376   2.485   2.680   2.564   2.704   2.927
167   N         0.763   0.910   0.599   1.122   1.307   0.919   0.774   0.984   0.499
168   A         1.117   1.126   1.146   1.027   1.019   1.074   0.912   0.890   0.860
169   P         2.267   2.353   2.473   2.376   2.485   2.680   2.564   2.704   2.927
170   K         2.267   2.353   2.473   1.870   2.006   2.163   2.564   2.704   2.927
171   K         1.496   1.380   1.361   1.216   1.098   1.059   1.600   1.380   1.304
172   P         2.267   2.353   2.473   2.376   2.485   2.680   2.564   2.704   2.927
173   L         1.117   1.126   1.146   1.162   1.173   1.202   0.912   0.890   0.860
174   T         2.267   2.353   2.473   2.414   2.534   2.719   2.564   2.704   2.927
175   V         0.072  -0.076  -0.161   0.529   0.318   0.242   0.086  -0.114  -0.228
176   F         1.117   1.074   1.107   1.408   1.324   1.355   0.912   0.782   0.776
177   F         1.117   1.126   1.146   1.330   1.324   1.309   0.912   0.890   0.860
178   A         0.763   0.611   0.528   0.824   0.601   0.512   0.774   0.532   0.383
179   Y         0.914   0.946   1.050   1.055   1.088   1.242   0.499   0.514   0.651
180   S         1.496   1.380   1.361   1.590   1.506   1.457   1.600   1.380   1.304
181   A        -0.788  -0.871  -0.812  -0.580  -0.626  -0.487  -0.740  -0.804  -0.719
182   Y        -0.567  -0.747  -0.744  -0.112  -0.393  -0.441  -0.465  -0.660  -0.643
183   V        -1.142  -1.272  -1.214  -0.897  -1.185  -1.102  -0.878  -0.980  -0.897
184   R         2.267   2.353   2.473   2.454   2.556   2.760   2.564   2.704   2.927
185   Q        -0.788  -0.871  -0.812  -0.720  -0.913  -0.848  -0.740  -0.804  -0.719
186   E        -1.142  -1.178  -1.154  -1.207  -1.249  -1.225  -0.878  -0.901  -0.845
187   L         0.914   1.137   1.183   0.857   1.256   1.297   0.499   0.912   0.938
188   R         0.763   0.611   0.528   1.118   0.881   0.781   0.774   0.532   0.383
189   E        -1.276  -1.225  -1.202  -1.133  -1.038  -1.007  -1.016  -0.950  -0.889
190   D         0.141   0.201   0.237  -0.274  -0.203  -0.151  -0.190  -0.110  -0.086
191   R         1.496   1.380   1.361   1.776   1.609   1.591   1.600   1.380   1.304
192   Q        -1.276  -1.321  -1.199  -1.316  -1.424  -1.273  -1.016  -1.022  -0.886
193   K        -0.567  -0.492  -0.653  -0.787  -0.753  -0.919  -0.465  -0.387  -0.542
194   A        -0.788  -0.885  -0.801  -0.891  -1.078  -0.916  -0.740  -0.816  -0.708
195   G         0.763   0.611   0.528   1.137   0.913   0.782   0.774   0.532   0.383
196   L         1.428   1.413   1.306   1.468   1.441   1.237   1.485   1.440   1.193
197   P         1.428   1.437   1.313   1.620   1.647   1.428   1.485   1.482   1.208
198   P         1.428   1.415   1.327   1.620   1.616   1.452   1.485   1.442   1.236
199   L         2.267   2.353   2.473   2.276   2.397   2.578   2.564   2.704   2.927
200   S         0.072  -0.112  -0.203   0.310   0.109  -0.039   0.086  -0.159  -0.283
201   S        -0.433  -0.487  -0.369  -0.698  -0.786  -0.646  -0.603  -0.643  -0.502
202   T        -0.788  -0.887  -0.798  -0.518  -0.611  -0.512  -0.740  -0.817  -0.706
203   E         0.426   0.292   0.352   0.180  -0.049   0.050   0.223   0.020   0.078
204   I        -0.300  -0.323  -0.281   0.041   0.047   0.110  -0.465  -0.457  -0.396
205   T        -0.433  -0.487  -0.369  -0.390  -0.476  -0.298  -0.603  -0.643  -0.502
206   Q        -0.433  -0.436  -0.360  -0.465  -0.539  -0.428  -0.603  -0.595  -0.493
207   E         0.763   0.768   0.569   0.773   0.775   0.570   0.774   0.779   0.450
208   I         0.426   0.290   0.327   0.690   0.494   0.541   0.223   0.017   0.043
209   S        -0.433  -0.487  -0.369  -0.843  -0.899  -0.774  -0.603  -0.643  -0.502
210   K        -0.433  -0.433  -0.352  -0.894  -0.796  -0.673  -0.603  -0.591  -0.485
211   K         0.054   0.135   0.230  -0.346  -0.111   0.002  -0.327  -0.212  -0.096
212   W         2.267   2.353   2.473   2.642   2.759   2.952   2.564   2.704   2.927
213   K        -0.300  -0.259  -0.248  -0.637  -0.396  -0.414  -0.465  -0.380  -0.353
214   E        -1.630  -1.511  -1.532  -1.643  -1.407  -1.514  -1.153  -1.044  -1.010
215   L         0.426   0.307   0.359   0.556   0.423   0.499   0.223   0.047   0.095
216   S         0.426   0.404   0.369   0.458   0.474   0.390   0.223   0.181   0.104
217   D        -0.213  -0.326  -0.280  -0.231  -0.473  -0.413  -0.327  -0.462  -0.400
218   N        -0.300  -0.043  -0.216  -0.638  -0.332  -0.495  -0.465  -0.189  -0.335
219   E         1.496   1.513   1.399   1.328   1.328   1.183   1.600   1.617   1.379
220   K         2.267   2.353   2.473   1.870   2.006   2.163   2.564   2.704   2.927
221   E        -0.567  -0.590  -0.678  -0.594  -0.644  -0.759  -0.465  -0.495  -0.571
222   K         0.141   0.103   0.206  -0.243  -0.225  -0.076  -0.190  -0.262  -0.135
223   W         0.914   0.946   1.050   1.128   1.154   1.306   0.499   0.514   0.651
224   K         0.426   0.305   0.337   0.128   0.003   0.057   0.223   0.043   0.053
225   Q        -1.142  -1.272  -1.214  -0.779  -0.989  -0.957  -0.878  -0.980  -0.897
226   A        -0.213  -0.255  -0.269  -0.538  -0.650  -0.710  -0.327  -0.374  -0.386
227   Y         2.267   2.353   2.473   2.538   2.653   2.845   2.564   2.704   2.927
228   N         0.275   0.407   0.397   0.387   0.623   0.621  -0.052   0.182   0.159
229   V        -1.630  -1.633  -1.555  -1.477  -1.487  -1.422  -1.153  -1.130  -1.026
230   E        -0.213  -0.346  -0.293  -0.631  -0.867  -0.810  -0.327  -0.484  -0.413
231   L         1.496   1.523   1.410   1.652   1.705   1.587   1.600   1.634   1.401
232   E        -0.788  -0.875  -0.800  -0.776  -0.843  -0.686  -0.740  -0.807  -0.708
233   N        -1.142  -1.272  -1.214  -0.756  -0.982  -0.897  -0.878  -0.980  -0.897
234   Y         2.267   2.353   2.473   2.538   2.653   2.845   2.564   2.704   2.927
235   Q         0.275   0.281   0.315   0.439   0.449   0.541  -0.052  -0.044   0.010
236   R        -1.276  -1.255  -1.209  -0.972  -0.984  -0.895  -1.016  -0.973  -0.895
237   E         0.275   0.308   0.315   0.031   0.108   0.166  -0.052  -0.013   0.012
238   K         0.763   0.639   0.510   0.574   0.436   0.263   0.774   0.573   0.354
239   S        -1.630  -1.626  -1.552  -1.364  -1.334  -1.294  -1.153  -1.126  -1.024
240   K         0.072  -0.084  -0.174  -0.147  -0.340  -0.514   0.086  -0.124  -0.246
241   Y         2.267   2.353   2.473   2.538   2.653   2.845   2.564   2.704   2.927
242   L        -0.788  -0.837  -0.798  -0.889  -1.008  -0.939  -0.740  -0.771  -0.706
243   E         0.426   0.303   0.340   0.189   0.012   0.068   0.223   0.040   0.060
244   A         0.054   0.112   0.218  -0.229  -0.069   0.058  -0.327  -0.248  -0.116
245   K         0.763   0.611   0.528   0.544   0.376   0.231   0.774   0.532   0.383
246   K        -0.213  -0.277  -0.292  -0.590  -0.675  -0.657  -0.327  -0.415  -0.416
247   N        -0.213  -0.259  -0.272  -0.026  -0.096  -0.138  -0.327  -0.377  -0.386
248   G        -0.213  -0.275  -0.292   0.006  -0.159  -0.163  -0.327  -0.413  -0.415
249   T        -1.142  -1.272  -1.214  -0.910  -1.197  -1.120  -0.878  -0.980  -0.897
250   L        -0.300  -0.323  -0.281  -0.381  -0.393  -0.296  -0.465  -0.457  -0.396
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   P         0.110   0.114   0.234  -0.092  -0.094   0.088  -0.256  -0.247  -0.094
281   A         0.110   0.108   0.253  -0.414  -0.402  -0.205  -0.256  -0.258  -0.070
282   S        -1.630  -1.443  -1.504  -1.262  -1.029  -1.054  -1.153  -0.981  -0.988
283   L        -1.142  -1.188  -1.159  -0.752  -0.820  -0.739  -0.878  -0.910  -0.849
284   E        -0.788  -0.475  -0.720  -0.812  -0.409  -0.706  -0.740  -0.417  -0.626
285   N        -0.901  -0.843  -0.792  -1.049  -0.996  -0.892  -0.853  -0.786  -0.701
286   G        -0.901  -0.952  -0.817  -0.826  -0.907  -0.729  -0.853  -0.875  -0.722
287   P        -0.924  -0.936  -0.857  -0.695  -0.718  -0.586  -0.863  -0.864  -0.760
288   T        -0.901  -0.843  -0.806  -0.954  -0.941  -0.828  -0.853  -0.780  -0.711
289   H        -0.921  -0.879  -0.806  -0.782  -0.733  -0.658  -0.878  -0.808  -0.715
290   A         0.072  -0.076  -0.161   0.233   0.025  -0.052   0.086  -0.114  -0.228
291   P        -0.788  -0.818  -0.792  -0.569  -0.629  -0.568  -0.740  -0.753  -0.699
292   V         0.072  -0.003  -0.132   0.360   0.224   0.005   0.086  -0.009  -0.189
293   P         1.117   1.126   1.146   1.065   1.031   1.012   0.912   0.890   0.860
294   I        -1.276  -1.316  -1.200  -1.102  -1.214  -0.993  -1.016  -1.018  -0.888
295   P        -0.788  -0.823  -0.793  -0.640  -0.724  -0.671  -0.740  -0.758  -0.701
296   F        -0.901  -0.782  -0.784  -0.996  -0.874  -0.818  -0.853  -0.732  -0.693
297   S        -0.749  -0.431  -0.698  -0.762  -0.359  -0.665  -0.673  -0.302  -0.593
298   L        -0.344  -0.379  -0.330  -0.574  -0.715  -0.619  -0.493  -0.525  -0.455
299   Q        -0.749  -0.895  -0.831  -0.544  -0.881  -0.782  -0.673  -0.818  -0.735
300   H        -0.901  -0.720  -0.783  -1.352  -1.137  -1.158  -0.853  -0.667  -0.692
301   A        -0.344  -0.282  -0.306  -0.607  -0.606  -0.554  -0.493  -0.431  -0.431
302   A        -0.749  -0.672  -0.723  -0.958  -0.832  -0.982  -0.673  -0.593  -0.620
303   E        -1.306  -1.152  -1.203  -1.058  -0.810  -0.912  -1.032  -0.885  -0.888
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   P         0.324   0.381   0.321   0.315   0.357   0.253   0.097   0.164   0.048
317   P        -1.023  -0.897  -0.867  -0.953  -0.754  -0.720  -0.960  -0.824  -0.769
318   V         0.110   0.322   0.249  -0.185   0.035  -0.018  -0.256   0.043  -0.071
319   -        -0.451  -0.383  -0.331  -0.894  -0.786  -0.687  -0.618  -0.530  -0.458
320   -        -1.396  -1.348  -1.246  -1.287  -1.245  -1.062  -1.107  -1.042  -0.923
321   -        -0.924  -0.884  -0.812  -0.947  -0.857  -0.822  -0.863  -0.807  -0.715
322   -        -0.451  -0.435  -0.339  -0.657  -0.607  -0.463  -0.618  -0.586  -0.467
323   -         0.199   0.196   0.298  -0.085  -0.077   0.079  -0.128  -0.130  -0.005
324   -        -1.396  -1.348  -1.246  -1.202  -1.111  -0.975  -1.107  -1.042  -0.923
325   -        -0.924  -0.886  -0.819  -1.061  -0.968  -0.886  -0.863  -0.809  -0.723
326   -        -0.273  -0.179  -0.215  -0.592  -0.424  -0.505  -0.373  -0.245  -0.299
327   -        -0.451  -0.423  -0.325  -0.346  -0.300  -0.155  -0.618  -0.574  -0.452
328   -        -0.451  -0.435  -0.347  -0.756  -0.744  -0.623  -0.618  -0.586  -0.475
329   E        -0.213  -0.220  -0.245  -0.365  -0.366  -0.390  -0.327  -0.348  -0.352
330   K        -1.276  -1.255  -1.209  -1.620  -1.477  -1.454  -1.016  -0.973  -0.895
331   R        -1.276  -1.254  -1.189  -1.128  -1.199  -1.008  -1.016  -0.971  -0.878
332   P        -0.788  -0.602  -0.717  -0.953  -0.709  -0.865  -0.740  -0.507  -0.616
333   H        -1.630  -1.443  -1.504  -1.251  -1.092  -1.036  -1.153  -0.981  -0.988
334   D        -0.213  -0.201  -0.181  -0.383  -0.390  -0.326  -0.327  -0.279  -0.259
335   D        -0.749  -0.588  -0.688  -0.783  -0.578  -0.683  -0.673  -0.490  -0.582
336   D        -0.924  -0.933  -0.857  -1.036  -1.112  -1.016  -0.863  -0.860  -0.760
337   G        -0.451  -0.436  -0.341  -0.587  -0.651  -0.480  -0.618  -0.580  -0.466
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   S         0.426   0.423   0.367   0.179   0.178  -0.028   0.223   0.200   0.107
346   S        -0.300  -0.242  -0.239  -0.273  -0.104  -0.095  -0.465  -0.361  -0.342
347   E         0.763   0.725   0.538   0.643   0.575   0.290   0.774   0.714   0.399
348   K         0.763   0.611   0.528   0.498   0.316   0.144   0.774   0.532   0.383
349   K         0.072   0.030  -0.122  -0.193  -0.220  -0.514   0.086   0.035  -0.176
350   K         0.426   0.407   0.359   0.076   0.077   0.002   0.223   0.187   0.088
351   K         1.496   1.380   1.361   1.216   1.098   1.059   1.600   1.380   1.304
352   K         2.267   2.353   2.473   1.870   2.006   2.163   2.564   2.704   2.927
353   K        -0.567  -0.728  -0.756  -0.682  -0.832  -0.885  -0.465  -0.640  -0.656
354   K         1.496   1.380   1.361   1.212   1.095   1.050   1.600   1.380   1.304
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   K         2.267   2.353   2.473   1.870   2.006   2.163   2.564   2.704   2.927
357   D        -0.213  -0.337  -0.280  -0.138  -0.324  -0.283  -0.327  -0.471  -0.400
358   K         0.763   0.611   0.528   0.443   0.225   0.040   0.774   0.532   0.383
359   K         0.072   0.050  -0.134  -0.131  -0.192  -0.425   0.086   0.039  -0.191
360   K         0.072  -0.084  -0.174  -0.107  -0.276  -0.443   0.086  -0.124  -0.246
361   D         0.054   0.135   0.230  -0.497  -0.441  -0.325  -0.327  -0.212  -0.096
362   K         0.763   0.607   0.500   0.498   0.282   0.100   0.774   0.525   0.339
363   S        -1.142  -1.205  -1.167  -1.056  -1.146  -1.127  -0.878  -0.925  -0.856
364   N        -0.213  -0.021  -0.179  -0.514  -0.260  -0.452  -0.327  -0.085  -0.271
365   S         0.141   0.360   0.307  -0.381  -0.015  -0.158  -0.190   0.139   0.022
366   S         0.639   0.780   0.566   0.626   0.849   0.473   0.586   0.795   0.444
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -         0.324   0.391   0.389   0.026   0.124   0.127   0.097   0.190   0.158
370   -        -0.457  -0.379  -0.318  -0.652  -0.535  -0.436  -0.608  -0.506  -0.434
371   -        -1.023  -0.972  -0.867  -0.804  -0.711  -0.567  -0.960  -0.892  -0.769
372   -         0.324   0.391   0.389  -0.031   0.068   0.059   0.097   0.190   0.158
373   I        -0.924  -0.852  -0.819  -1.030  -0.974  -0.855  -0.863  -0.780  -0.723
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03973
Output conservation file - output/Q03973
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
