1     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    M         0.681   0.747   0.490   0.966   1.058   0.694   0.682   0.781   0.322
37    P        -0.785  -0.612  -0.763  -0.772  -0.529  -0.694  -0.850  -0.620  -0.772
38    V         0.681   0.559   0.459   0.766   0.599   0.458   0.682   0.480   0.265
39    I        -0.055   0.007  -0.246   0.034   0.127  -0.290  -0.124  -0.032  -0.409
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    E         0.355   0.327   0.326   0.120   0.085   0.064   0.135   0.069   0.011
42    I         1.341   1.383   1.458   1.323   1.392   1.506   1.447   1.507   1.619
43    N        -0.237  -0.041  -0.237  -0.267   0.041  -0.269  -0.412  -0.122  -0.399
44    D        -0.540  -0.541  -0.734  -0.474  -0.476  -0.743  -0.522  -0.520  -0.733
45    Q        -1.277  -1.332  -1.207  -1.229  -1.292  -1.132  -1.178  -1.195  -1.020
46    E        -0.974  -0.819  -0.804  -1.218  -0.982  -0.940  -1.068  -0.878  -0.817
47    Q         0.052  -0.020  -0.233   0.282   0.164  -0.130   0.025  -0.081  -0.390
48    F         0.681   0.559   0.459   0.778   0.649   0.517   0.682   0.480   0.265
49    T        -0.540  -0.712  -0.778  -0.325  -0.572  -0.710  -0.522  -0.728  -0.785
50    Y         0.052   0.009  -0.222   0.053   0.003  -0.270   0.025  -0.043  -0.374
51    L         0.052  -0.184  -0.256   0.106  -0.193  -0.284   0.025  -0.305  -0.424
52    T         0.052  -0.184  -0.256   0.206  -0.139  -0.286   0.025  -0.305  -0.424
53    T        -0.974  -0.989  -0.837  -1.044  -1.071  -0.850  -1.068  -1.054  -0.854
54    T        -1.277  -1.218  -1.184  -1.291  -1.199  -1.142  -1.178  -1.094  -1.000
55    A        -1.375  -1.273  -1.211  -1.413  -1.278  -1.180  -1.267  -1.143  -1.023
56    A        -0.785  -0.853  -0.796  -0.811  -0.916  -0.797  -0.850  -0.915  -0.811
57    G        -1.394  -1.392  -1.225  -1.291  -1.330  -1.072  -1.275  -1.248  -1.035
58    D        -1.277  -1.258  -1.194  -1.272  -1.287  -1.185  -1.178  -1.142  -1.011
59    K        -0.237  -0.369  -0.323  -0.184  -0.384  -0.323  -0.412  -0.586  -0.525
60    L         0.681   0.573   0.467   0.627   0.493   0.338   0.682   0.504   0.280
61    I        -0.237  -0.220  -0.302  -0.284  -0.291  -0.426  -0.412  -0.404  -0.499
62    V        -0.785  -0.907  -0.807  -0.882  -1.075  -0.920  -0.850  -0.955  -0.820
63    L        -0.237  -0.236  -0.299  -0.356  -0.382  -0.444  -0.412  -0.424  -0.492
64    Y         0.052  -0.184  -0.256   0.398   0.059  -0.115   0.025  -0.305  -0.424
65    F         1.341   1.383   1.458   1.311   1.381   1.494   1.447   1.507   1.619
66    H         0.355   0.336   0.334   0.579   0.547   0.508   0.135   0.085   0.027
67    T         0.355   0.244   0.317   0.285   0.048   0.133   0.135  -0.088  -0.008
68    S         0.182   0.267   0.332  -0.033   0.126   0.185  -0.193  -0.045   0.022
69    W         1.341   1.383   1.458   1.568   1.629   1.737   1.447   1.507   1.619
70    A         1.341   1.383   1.458   1.198   1.251   1.388   1.447   1.507   1.619
71    E        -0.556  -0.449  -0.349  -0.930  -0.770  -0.599  -0.850  -0.699  -0.557
72    P         1.341   1.383   1.458   1.382   1.446   1.561   1.447   1.507   1.619
73    C         1.341   1.383   1.458   1.568   1.633   1.737   1.447   1.507   1.619
74    K        -0.785  -0.693  -0.783  -0.752  -0.675  -0.766  -0.850  -0.752  -0.796
75    A        -0.556  -0.449  -0.349  -0.761  -0.587  -0.432  -0.850  -0.699  -0.557
76    L        -0.540  -0.375  -0.717  -0.177   0.053  -0.504  -0.522  -0.303  -0.714
77    K        -1.088  -1.055  -1.158  -0.870  -0.858  -1.044  -0.959  -0.913  -0.974
78    Q        -1.277  -1.252  -1.177  -1.246  -1.188  -1.119  -1.178  -1.124  -0.994
79    V         0.681   0.747   0.490   0.744   0.822   0.457   0.682   0.781   0.322
80    F        -0.540  -0.571  -0.740  -0.346  -0.408  -0.641  -0.522  -0.557  -0.741
81    E        -0.785  -0.784  -0.790  -0.753  -0.723  -0.754  -0.850  -0.821  -0.802
82    A        -0.859  -0.871  -0.809  -0.965  -0.966  -0.866  -0.959  -0.944  -0.825
83    I        -0.237  -0.271  -0.285  -0.361  -0.393  -0.428  -0.412  -0.434  -0.469
84    S         0.126   0.177   0.300  -0.317  -0.239  -0.035  -0.303  -0.220  -0.041
85    N        -1.394  -1.371  -1.223  -1.541  -1.500  -1.274  -1.275  -1.231  -1.034
86    E        -0.431  -0.365  -0.327  -0.741  -0.625  -0.573  -0.692  -0.603  -0.531
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    P        -1.244  -1.252  -1.203  -1.155  -1.130  -1.029  -1.124  -1.120  -1.015
89    S        -1.244  -1.245  -1.199  -1.230  -1.234  -1.159  -1.124  -1.113  -1.012
90    N        -1.088  -1.161  -1.178  -0.760  -0.899  -0.900  -0.959  -1.030  -0.993
91    S        -0.785  -0.748  -0.782  -0.754  -0.691  -0.762  -0.850  -0.788  -0.795
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    N        -0.481  -0.445  -0.361  -0.684  -0.625  -0.497  -0.740  -0.683  -0.574
96    V        -0.540  -0.671  -0.765  -0.365  -0.596  -0.739  -0.522  -0.685  -0.769
97    S        -0.974  -0.869  -0.821  -1.204  -1.059  -0.956  -1.068  -0.945  -0.838
98    F         0.681   0.559   0.459   0.778   0.649   0.517   0.682   0.480   0.265
99    L         0.052   0.020  -0.213   0.067   0.012  -0.304   0.025  -0.030  -0.362
100   S         0.052  -0.020  -0.217   0.042  -0.046  -0.354   0.025  -0.078  -0.368
101   I         0.355   0.434   0.365   0.296   0.418   0.277   0.135   0.265   0.088
102   D        -0.859  -0.859  -0.800  -0.897  -0.898  -0.840  -0.959  -0.930  -0.815
103   A         1.341   1.383   1.458   1.198   1.251   1.388   1.447   1.507   1.619
104   D         0.182   0.172   0.297  -0.085  -0.143   0.031  -0.193  -0.230  -0.046
105   E         0.052   0.033  -0.203   0.015   0.000  -0.322   0.025  -0.010  -0.346
106   N        -1.277  -1.208  -1.177  -1.185  -1.117  -1.006  -1.178  -1.088  -0.994
107   S        -0.859  -0.752  -0.781  -0.965  -0.831  -0.853  -0.959  -0.820  -0.794
108   E         0.355   0.351   0.346   0.120   0.124   0.097   0.135   0.113   0.050
109   I         1.341   1.383   1.458   1.323   1.392   1.506   1.447   1.507   1.619
110   S         0.355   0.324   0.337   0.120   0.056   0.040   0.135   0.064   0.032
111   E         1.341   1.383   1.458   1.134   1.211   1.327   1.447   1.507   1.619
112   L        -0.785  -0.823  -0.804  -0.914  -0.994  -0.939  -0.850  -0.892  -0.820
113   F         0.681   0.559   0.459   0.774   0.644   0.508   0.682   0.480   0.265
114   E        -0.237  -0.374  -0.323  -0.394  -0.568  -0.487  -0.412  -0.591  -0.526
115   I         0.182   0.263   0.323  -0.008   0.118   0.199  -0.193  -0.051   0.006
116   S         0.052  -0.184  -0.256   0.073  -0.234  -0.347   0.025  -0.305  -0.424
117   A         0.681   0.772   0.488   0.610   0.725   0.328   0.682   0.819   0.318
118   V         1.341   1.383   1.458   1.330   1.378   1.513   1.447   1.507   1.619
119   P         1.341   1.383   1.458   1.382   1.446   1.561   1.447   1.507   1.619
120   Y         0.052  -0.184  -0.256   0.389   0.045  -0.136   0.025  -0.305  -0.424
121   F         0.681   0.559   0.459   0.724   0.568   0.383   0.682   0.480   0.265
122   I         0.126   0.192   0.311  -0.118  -0.018   0.174  -0.303  -0.191  -0.019
123   I        -0.540  -0.362  -0.708  -0.441  -0.207  -0.656  -0.522  -0.287  -0.703
124   I         0.052  -0.020  -0.233   0.152   0.046  -0.320   0.025  -0.081  -0.390
125   H        -0.237  -0.197  -0.294   0.001   0.049  -0.094  -0.412  -0.369  -0.487
126   K        -1.088  -1.035  -1.146  -0.833  -0.764  -0.965  -0.959  -0.890  -0.962
127   G        -1.088  -1.132  -1.165  -0.855  -0.963  -1.037  -0.959  -1.002  -0.980
128   T         0.052  -0.184  -0.256   0.242  -0.079  -0.203   0.025  -0.305  -0.424
129   I         0.355   0.244   0.317   0.296   0.088   0.184   0.135  -0.088  -0.008
130   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
131   K        -0.540  -0.704  -0.770  -0.354  -0.638  -0.752  -0.522  -0.720  -0.775
132   E         0.052  -0.184  -0.256   0.038  -0.250  -0.349   0.025  -0.305  -0.424
133   L        -0.540  -0.704  -0.770  -0.437  -0.684  -0.733  -0.522  -0.720  -0.775
134   S         1.341   1.383   1.458   1.188   1.258   1.378   1.447   1.507   1.619
135   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
136   A         0.681   0.559   0.459   0.610   0.438   0.277   0.682   0.480   0.265
137   D        -0.237  -0.378  -0.316  -0.211  -0.433  -0.372  -0.412  -0.598  -0.516
138   P         0.681   0.559   0.459   0.796   0.631   0.449   0.682   0.480   0.265
139   K        -0.540  -0.678  -0.756  -0.279  -0.495  -0.585  -0.522  -0.692  -0.760
140   E         0.355   0.244   0.317   0.120  -0.058   0.049   0.135  -0.088  -0.008
141   Y        -0.785  -0.837  -0.805  -0.756  -0.872  -0.780  -0.850  -0.904  -0.821
142   V        -1.696  -1.711  -1.530  -1.581  -1.582  -1.357  -1.396  -1.373  -1.148
143   S        -0.785  -0.730  -0.774  -0.889  -0.800  -0.850  -0.850  -0.763  -0.784
144   L        -0.540  -0.362  -0.708  -0.498  -0.263  -0.757  -0.522  -0.287  -0.703
145   L         0.182   0.171   0.297  -0.128  -0.154   0.055  -0.193  -0.232  -0.046
146   E        -0.859  -0.864  -0.799  -1.005  -1.002  -0.911  -0.959  -0.934  -0.814
147   D        -1.277  -1.273  -1.195  -1.257  -1.289  -1.178  -1.178  -1.155  -1.011
148   C        -1.392  -1.431  -1.217  -1.176  -1.161  -0.895  -1.287  -1.280  -1.030
149   K        -1.999  -1.959  -1.788  -1.831  -1.803  -1.522  -1.506  -1.445  -1.228
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   N        -1.696  -1.709  -1.523  -1.714  -1.704  -1.468  -1.396  -1.371  -1.143
152   S        -1.392  -1.353  -1.209  -1.364  -1.297  -1.089  -1.287  -1.223  -1.024
153   V        -1.581  -1.587  -1.505  -1.401  -1.484  -1.356  -1.287  -1.274  -1.129
154   N        -1.392  -1.369  -1.211  -1.453  -1.431  -1.207  -1.287  -1.231  -1.025
155   S        -1.088  -1.036  -1.147  -0.973  -0.903  -1.046  -0.959  -0.894  -0.964
156   G        -2.303  -2.217  -2.025  -1.967  -1.850  -1.599  -1.615  -1.524  -1.296
157   S        -1.696  -1.687  -1.525  -1.785  -1.744  -1.522  -1.396  -1.357  -1.144
158   S        -1.277  -1.168  -1.174  -1.320  -1.168  -1.163  -1.178  -1.058  -0.994
159   Q        -1.277  -1.143  -1.171  -1.419  -1.252  -1.253  -1.178  -1.040  -0.991
160   T        -1.375  -1.271  -1.191  -1.494  -1.351  -1.239  -1.267  -1.149  -1.007
161   H        -0.897  -0.785  -0.801  -0.910  -0.786  -0.770  -0.981  -0.855  -0.816
162   T        -1.722  -1.616  -1.514  -1.692  -1.585  -1.399  -1.410  -1.294  -1.135
163   M        -1.375  -1.312  -1.200  -1.400  -1.337  -1.118  -1.267  -1.186  -1.015
164   E        -1.244  -1.170  -1.172  -1.244  -1.134  -1.209  -1.124  -1.032  -0.987
165   N        -1.277  -1.245  -1.188  -1.356  -1.340  -1.196  -1.178  -1.134  -1.006
166   A        -0.237  -0.282  -0.287  -0.337  -0.392  -0.398  -0.412  -0.450  -0.472
167   N        -1.999  -1.955  -1.791  -1.781  -1.710  -1.522  -1.506  -1.443  -1.230
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   V        -1.277  -1.164  -1.176  -1.304  -1.177  -1.180  -1.178  -1.055  -0.995
174   N        -0.785  -0.641  -0.752  -0.770  -0.535  -0.745  -0.850  -0.654  -0.759
175   E        -0.540  -0.504  -0.724  -0.541  -0.482  -0.849  -0.522  -0.479  -0.722
176   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   S        -1.028  -1.025  -0.844  -1.273  -1.274  -0.988  -1.124  -1.089  -0.860
178   H        -0.681  -0.685  -0.774  -0.567  -0.588  -0.646  -0.696  -0.694  -0.780
179   N        -0.897  -0.715  -0.778  -0.829  -0.564  -0.652  -0.981  -0.749  -0.789
180   D        -0.897  -0.821  -0.806  -1.044  -0.942  -0.905  -0.981  -0.884  -0.821
181   E        -0.897  -0.790  -0.797  -0.923  -0.799  -0.785  -0.981  -0.859  -0.813
182   D        -1.722  -1.714  -1.537  -1.712  -1.678  -1.431  -1.410  -1.373  -1.153
183   D        -1.394  -1.367  -1.215  -1.397  -1.352  -1.126  -1.275  -1.227  -1.026
184   D        -0.989  -0.955  -0.829  -1.144  -1.118  -0.914  -1.081  -1.021  -0.845
185   -        -1.479  -1.425  -1.238  -1.512  -1.423  -1.170  -1.353  -1.275  -1.046
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   D        -1.394  -1.376  -1.225  -1.341  -1.336  -1.125  -1.275  -1.235  -1.035
195   E        -1.375  -1.313  -1.207  -1.497  -1.386  -1.249  -1.267  -1.184  -1.021
196   E        -1.244  -1.279  -1.187  -1.238  -1.273  -1.128  -1.124  -1.144  -1.001
197   E        -1.277  -1.350  -1.198  -1.389  -1.485  -1.275  -1.178  -1.213  -1.013
198   E        -1.696  -1.519  -1.509  -1.670  -1.376  -1.390  -1.396  -1.221  -1.133
199   E         0.052  -0.184  -0.256   0.019  -0.281  -0.393   0.025  -0.305  -0.424
200   E         0.052  -0.184  -0.256   0.020  -0.280  -0.390   0.025  -0.305  -0.424
201   T        -0.785  -0.888  -0.796  -0.784  -0.920  -0.825  -0.850  -0.931  -0.807
202   E        -0.540  -0.678  -0.756  -0.518  -0.703  -0.800  -0.522  -0.692  -0.760
203   E         0.681   0.573   0.467   0.545   0.419   0.233   0.682   0.504   0.280
204   Q        -0.481  -0.314  -0.311  -0.794  -0.521  -0.531  -0.740  -0.493  -0.502
205   I         0.052   0.184  -0.189   0.102   0.271  -0.196   0.025   0.213  -0.326
206   N         0.052  -0.011  -0.226   0.255   0.164  -0.154   0.025  -0.069  -0.380
207   A        -0.785  -0.797  -0.788  -0.884  -0.861  -0.821  -0.850  -0.837  -0.801
208   R         1.341   1.383   1.458   1.483   1.548   1.657   1.447   1.507   1.619
209   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
210   T        -1.696  -1.690  -1.522  -1.573  -1.592  -1.350  -1.396  -1.359  -1.143
211   K         0.052  -0.184  -0.256   0.234  -0.088  -0.219   0.025  -0.305  -0.424
212   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
213   V         0.126   0.168   0.298  -0.095  -0.048   0.169  -0.303  -0.238  -0.045
214   N        -0.859  -0.740  -0.788  -0.792  -0.650  -0.663  -0.959  -0.824  -0.805
215   A         1.341   1.383   1.458   1.198   1.251   1.388   1.447   1.507   1.619
216   A         0.681   0.573   0.467   0.663   0.537   0.423   0.682   0.504   0.280
217   P         0.681   0.573   0.467   0.821   0.691   0.525   0.682   0.504   0.280
218   V         0.681   0.815   0.491   0.762   0.919   0.499   0.682   0.882   0.323
219   M         1.341   1.383   1.458   1.528   1.592   1.700   1.447   1.507   1.619
220   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
221   F         1.341   1.383   1.458   1.311   1.381   1.494   1.447   1.507   1.619
222   M         0.681   0.573   0.467   0.942   0.799   0.595   0.682   0.504   0.280
223   K         1.341   1.383   1.458   1.352   1.414   1.534   1.447   1.507   1.619
224   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
225   S        -0.366  -0.251  -0.282  -0.522  -0.311  -0.348  -0.631  -0.450  -0.470
226   P         1.341   1.383   1.458   1.382   1.446   1.561   1.447   1.507   1.619
227   S         0.681   0.762   0.484   0.601   0.719   0.317   0.682   0.804   0.312
228   E        -0.237  -0.053  -0.259  -0.495  -0.206  -0.542  -0.412  -0.148  -0.431
229   P         1.341   1.383   1.458   1.382   1.446   1.561   1.447   1.507   1.619
230   K        -0.366  -0.390  -0.309  -0.434  -0.460  -0.349  -0.631  -0.620  -0.507
231   C         1.341   1.383   1.458   1.568   1.633   1.737   1.447   1.507   1.619
232   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
233   F         1.341   1.383   1.458   1.311   1.381   1.494   1.447   1.507   1.619
234   S         1.341   1.383   1.458   1.188   1.258   1.378   1.447   1.507   1.619
235   R         1.341   1.383   1.458   1.483   1.548   1.657   1.447   1.507   1.619
236   Q         0.681   0.573   0.467   0.830   0.693   0.527   0.682   0.504   0.280
237   L         0.052   0.162  -0.193   0.102   0.244  -0.203   0.025   0.184  -0.333
238   V         1.341   1.383   1.458   1.330   1.378   1.513   1.447   1.507   1.619
239   G         0.126   0.167   0.297  -0.169  -0.118   0.098  -0.303  -0.239  -0.047
240   I         0.681   0.573   0.467   0.736   0.601   0.409   0.682   0.504   0.280
241   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
242   R         1.341   1.383   1.458   1.483   1.548   1.657   1.447   1.507   1.619
243   E         1.341   1.383   1.458   1.134   1.211   1.327   1.447   1.507   1.619
244   H         0.052  -0.184  -0.256   0.437   0.117  -0.036   0.025  -0.305  -0.424
245   Q        -0.540  -0.712  -0.778  -0.254  -0.528  -0.616  -0.522  -0.728  -0.785
246   V         0.355   0.440   0.380   0.301   0.418   0.306   0.135   0.275   0.115
247   R         0.052  -0.184  -0.256   0.368   0.047  -0.098   0.025  -0.305  -0.424
248   F         0.355   0.244   0.317   0.353   0.191   0.297   0.135  -0.088  -0.008
249   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
250   F         1.341   1.383   1.458   1.311   1.381   1.494   1.447   1.507   1.619
251   F         1.341   1.383   1.458   1.311   1.381   1.494   1.447   1.507   1.619
252   D         0.355   0.244   0.317   0.342   0.147   0.236   0.135  -0.088  -0.008
253   I         1.341   1.383   1.458   1.323   1.392   1.506   1.447   1.507   1.619
254   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
255   R        -0.481  -0.486  -0.370  -0.563  -0.633  -0.437  -0.740  -0.748  -0.586
256   D         1.341   1.383   1.458   1.355   1.424   1.536   1.447   1.507   1.619
257   E         0.355   0.469   0.385   0.265   0.460   0.255   0.135   0.326   0.126
258   S        -1.088  -1.078  -1.152  -1.072  -1.083  -1.206  -0.959  -0.936  -0.968
259   V         1.341   1.383   1.458   1.330   1.378   1.513   1.447   1.507   1.619
260   R         1.341   1.383   1.458   1.483   1.548   1.657   1.447   1.507   1.619
261   Q         0.681   0.747   0.490   0.830   0.918   0.566   0.682   0.781   0.322
262   N         0.355   0.453   0.381   0.370   0.515   0.379   0.135   0.299   0.119
263   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
264   K         1.341   1.383   1.458   1.352   1.414   1.534   1.447   1.507   1.619
265   K        -0.540  -0.678  -0.756  -0.350  -0.587  -0.719  -0.522  -0.692  -0.760
266   F         1.341   1.383   1.458   1.311   1.381   1.494   1.447   1.507   1.619
267   S         0.681   0.559   0.459   0.601   0.444   0.272   0.682   0.480   0.265
268   E         0.681   0.795   0.491   0.760   0.921   0.463   0.682   0.852   0.324
269   W         1.341   1.383   1.458   1.568   1.629   1.737   1.447   1.507   1.619
270   P         1.341   1.383   1.458   1.382   1.446   1.561   1.447   1.507   1.619
271   T         1.341   1.383   1.458   1.355   1.416   1.536   1.447   1.507   1.619
272   F         0.681   0.559   0.459   0.774   0.644   0.508   0.682   0.480   0.265
273   P         1.341   1.383   1.458   1.382   1.446   1.561   1.447   1.507   1.619
274   Q         1.341   1.383   1.458   1.394   1.453   1.573   1.447   1.507   1.619
275   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
276   Y         0.681   0.559   0.459   1.007   0.868   0.719   0.682   0.480   0.265
277   I         0.681   0.559   0.459   0.756   0.605   0.442   0.682   0.480   0.265
278   N        -1.088  -1.167  -1.175  -0.833  -0.965  -1.014  -0.959  -1.035  -0.990
279   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
280   E         1.341   1.383   1.458   1.134   1.211   1.327   1.447   1.507   1.619
281   F         0.355   0.323   0.333   0.240   0.174   0.133   0.135   0.061   0.024
282   Q         0.355   0.244   0.317   0.364   0.143   0.239   0.135  -0.088  -0.008
283   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
284   G         1.341   1.383   1.458   1.384   1.443   1.564   1.447   1.507   1.619
285   L         1.341   1.383   1.458   1.195   1.256   1.385   1.447   1.507   1.619
286   D         1.341   1.383   1.458   1.355   1.424   1.536   1.447   1.507   1.619
287   I         1.341   1.383   1.458   1.323   1.392   1.506   1.447   1.507   1.619
288   I         0.126   0.183   0.305  -0.118  -0.035   0.162  -0.303  -0.208  -0.031
289   K         0.681   0.573   0.467   0.765   0.622   0.434   0.682   0.504   0.280
290   E         1.341   1.383   1.458   1.134   1.211   1.327   1.447   1.507   1.619
291   S         0.052  -0.184  -0.256   0.063  -0.248  -0.371   0.025  -0.305  -0.424
292   L         0.126   0.167   0.298  -0.217  -0.157   0.051  -0.303  -0.239  -0.045
293   E         0.052  -0.020  -0.233  -0.005  -0.104  -0.411   0.025  -0.081  -0.390
294   E        -0.237  -0.242  -0.314  -0.390  -0.424  -0.472  -0.412  -0.468  -0.515
295   D         0.681   0.573   0.467   0.795   0.671   0.503   0.682   0.504   0.280
296   P        -0.785  -0.818  -0.796  -0.830  -0.919  -0.931  -0.850  -0.881  -0.811
297   D        -0.897  -0.740  -0.801  -1.039  -0.781  -0.915  -0.981  -0.788  -0.815
298   F         1.341   1.383   1.458   1.313   1.387   1.496   1.447   1.507   1.619
299   L         0.355   0.346   0.337   0.240   0.216   0.143   0.135   0.104   0.033
300   Q        -0.366  -0.400  -0.318  -0.527  -0.520  -0.423  -0.631  -0.632  -0.519
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   H        -1.088  -1.167  -1.175  -0.721  -0.905  -0.974  -0.959  -1.035  -0.990
312   A        -0.237  -0.282  -0.287  -0.303  -0.345  -0.334  -0.412  -0.450  -0.472
313   L        -0.785  -0.793  -0.777  -0.839  -0.844  -0.806  -0.850  -0.832  -0.787
314   Q        -1.999  -1.890  -1.772  -1.805  -1.617  -1.515  -1.506  -1.393  -1.218
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   S        -0.974  -0.945  -0.836  -1.226  -1.185  -1.022  -1.068  -1.025  -0.853
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03835
Output conservation file - output/Q03835
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
