1     M         2.126   2.130   2.232   2.431   2.436   2.602   2.413   2.418   2.594
2     V        -0.941  -0.938  -0.898  -0.996  -0.990  -0.942  -0.828  -0.825  -0.758
3     K        -0.505  -0.486  -0.458  -0.258  -0.230  -0.180  -0.605  -0.586  -0.536
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    N         0.069   0.051   0.085   0.096   0.055   0.063  -0.199  -0.226  -0.193
20    H        -0.962  -0.932  -0.924  -0.704  -0.648  -0.654  -0.838  -0.806  -0.777
21    F        -0.962  -0.969  -0.914  -0.681  -0.688  -0.595  -0.838  -0.845  -0.767
22    G        -0.941  -0.934  -0.901  -1.129  -1.131  -1.046  -0.828  -0.821  -0.760
23    H        -0.157  -0.194  -0.319   0.300   0.245   0.062  -0.146  -0.195  -0.353
24    L        -0.793  -0.821  -0.854  -0.817  -0.860  -0.891  -0.658  -0.688  -0.706
25    K        -0.941  -0.919  -0.905  -0.966  -0.948  -0.880  -0.828  -0.809  -0.764
26    S        -0.401  -0.422  -0.398  -0.688  -0.719  -0.674  -0.487  -0.508  -0.467
27    F         0.551   0.523   0.344   0.454   0.413   0.133   0.537   0.495   0.208
28    V         0.235   0.245   0.205   0.063   0.068  -0.019   0.025   0.032  -0.027
29    G        -0.941  -0.919  -0.896  -1.107  -1.082  -1.017  -0.828  -0.809  -0.756
30    G        -0.157  -0.180  -0.315  -0.247  -0.283  -0.484  -0.146  -0.176  -0.349
31    N        -0.401  -0.421  -0.420  -0.468  -0.495  -0.480  -0.487  -0.509  -0.491
32    V         1.235   1.229   1.126   1.117   1.107   0.953   1.252   1.241   1.019
33    V         1.235   1.234   1.116   1.346   1.343   1.168   1.252   1.250   0.999
34    A         0.125   0.125   0.145  -0.233  -0.234  -0.230  -0.141  -0.140  -0.116
35    L         0.410   0.393   0.275   0.189   0.161  -0.072   0.323   0.298   0.101
36    G         0.755   0.758   0.852   0.368   0.370   0.514   0.323   0.328   0.458
37    A        -0.048  -0.045   0.044  -0.321  -0.309  -0.173  -0.373  -0.370  -0.254
38    G         1.315   1.300   1.170   1.295   1.275   1.085   1.390   1.364   1.103
39    T         1.315   1.300   1.170   1.485   1.465   1.273   1.390   1.364   1.103
40    P         0.235   0.222   0.192   0.472   0.453   0.411   0.025   0.007  -0.043
41    Y         2.126   2.130   2.232   2.304   2.310   2.473   2.413   2.418   2.594
42    L         0.942   0.933   0.948   0.642   0.623   0.627   0.707   0.687   0.661
43    F         1.315   1.311   1.176   1.550   1.547   1.353   1.390   1.383   1.116
44    S         0.942   0.975   0.973   0.561   0.618   0.582   0.707   0.769   0.714
45    F        -0.401  -0.372  -0.422  -0.475  -0.440  -0.498  -0.487  -0.458  -0.493
46    Y         0.235   0.221   0.182   0.424   0.403   0.352   0.025  -0.001  -0.061
47    A         1.315   1.344   1.185   1.341   1.380   1.131   1.390   1.438   1.131
48    P         2.126   2.130   2.232   2.377   2.382   2.547   2.413   2.418   2.594
49    Q         2.126   2.130   2.232   2.392   2.398   2.562   2.413   2.418   2.594
50    L         0.775   0.775   0.861   0.381   0.379   0.496   0.366   0.365   0.478
51    L        -0.941  -0.931  -0.905  -1.167  -1.155  -1.129  -0.828  -0.819  -0.764
52    S        -0.941  -0.947  -0.924  -0.975  -0.994  -0.950  -0.828  -0.833  -0.780
53    K        -0.009  -0.013   0.057   0.149   0.142   0.248  -0.316  -0.323  -0.235
54    C        -0.009  -0.001   0.067  -0.258  -0.244  -0.130  -0.316  -0.305  -0.220
55    H         0.235   0.261   0.208   0.360   0.415   0.301   0.025   0.068  -0.014
56    I         0.235   0.220   0.191  -0.071  -0.097  -0.145   0.025  -0.000  -0.044
57    P         0.139   0.137   0.154   0.213   0.215   0.265  -0.146  -0.147  -0.112
58    V         0.235   0.220   0.185   0.209   0.179   0.110   0.025  -0.001  -0.056
59    S         0.235   0.210   0.185  -0.060  -0.099  -0.143   0.025  -0.011  -0.054
60    A        -0.793  -0.826  -0.861  -0.451  -0.508  -0.579  -0.658  -0.693  -0.713
61    S         0.551   0.530   0.349   0.458   0.428   0.165   0.537   0.505   0.216
62    S        -0.401  -0.400  -0.406  -0.568  -0.561  -0.530  -0.487  -0.481  -0.472
63    K        -0.401  -0.415  -0.414  -0.368  -0.390  -0.404  -0.487  -0.502  -0.486
64    L         0.942   0.928   0.945   0.701   0.673   0.649   0.707   0.677   0.654
65    S         0.775   0.774   0.862   0.235   0.232   0.361   0.366   0.362   0.480
66    F        -0.157  -0.180  -0.315  -0.147  -0.180  -0.354  -0.146  -0.176  -0.349
67    S        -0.401  -0.409  -0.420  -0.577  -0.598  -0.594  -0.487  -0.498  -0.491
68    L        -0.401  -0.372  -0.422  -0.747  -0.707  -0.799  -0.487  -0.458  -0.493
69    T         0.775   0.780   0.862   0.730   0.740   0.857   0.366   0.375   0.480
70    I         0.139   0.137   0.159  -0.235  -0.236  -0.192  -0.146  -0.147  -0.106
71    G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
72    S        -0.401  -0.388  -0.408  -0.436  -0.423  -0.408  -0.487  -0.474  -0.477
73    S        -0.941  -0.955  -0.916  -1.106  -1.119  -1.036  -0.828  -0.840  -0.773
74    L        -0.157  -0.169  -0.286  -0.322  -0.346  -0.557  -0.146  -0.162  -0.311
75    M        -0.549  -0.546  -0.487  -0.826  -0.818  -0.733  -0.658  -0.654  -0.568
76    G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
77    I        -0.401  -0.400  -0.402  -0.453  -0.446  -0.458  -0.487  -0.488  -0.472
78    L        -0.793  -0.814  -0.852  -0.518  -0.554  -0.646  -0.658  -0.681  -0.703
79    A         0.235   0.246   0.207   0.070   0.097   0.023   0.025   0.048  -0.015
80    G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
81    I        -0.941  -0.955  -0.916  -1.025  -1.031  -0.944  -0.828  -0.840  -0.773
82    V         0.235   0.221   0.188   0.142   0.125   0.071   0.025   0.006  -0.053
83    V         0.775   0.786   0.871   0.493   0.517   0.638   0.366   0.387   0.499
84    D         2.126   2.130   2.232   2.390   2.395   2.560   2.413   2.418   2.594
85    R        -0.941  -0.927  -0.907  -0.453  -0.438  -0.375  -0.828  -0.816  -0.766
86    -        -0.510  -0.512  -0.467  -0.302  -0.301  -0.231  -0.596  -0.598  -0.538
87    S         0.942   0.928   0.945   0.633   0.602   0.579   0.707   0.677   0.654
88    P         0.235   0.229   0.191   0.374   0.362   0.291   0.025   0.013  -0.045
89    K        -0.941  -0.936  -0.910  -0.541  -0.534  -0.477  -0.828  -0.823  -0.768
90    L        -1.724  -1.723  -1.645  -1.571  -1.569  -1.449  -1.169  -1.167  -1.069
91    S        -0.009  -0.002   0.054  -0.225  -0.210  -0.169  -0.316  -0.307  -0.240
92    C         0.235   0.211   0.185   0.231   0.198   0.169   0.025  -0.012  -0.053
93    L        -0.941  -0.940  -0.905  -1.282  -1.274  -1.239  -0.828  -0.827  -0.764
94    I         0.775   0.778   0.863   0.331   0.336   0.452   0.366   0.370   0.482
95    G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
96    S         0.235   0.226   0.189  -0.116  -0.133  -0.205   0.025   0.011  -0.049
97    M        -0.401  -0.423  -0.426  -0.529  -0.570  -0.570  -0.487  -0.512  -0.499
98    C        -0.941  -0.945  -0.909  -0.963  -0.972  -0.941  -0.828  -0.831  -0.767
99    V        -0.941  -0.951  -0.922  -1.046  -1.061  -0.986  -0.828  -0.836  -0.779
100   F        -0.549  -0.549  -0.485  -0.835  -0.837  -0.722  -0.658  -0.658  -0.568
101   I        -0.401  -0.375  -0.405  -0.719  -0.679  -0.727  -0.487  -0.456  -0.475
102   A         0.942   0.928   0.945   0.711   0.683   0.681   0.707   0.677   0.654
103   Y         2.126   2.130   2.232   2.304   2.310   2.473   2.413   2.418   2.594
104   L        -1.332  -1.334  -1.288  -1.420  -1.430  -1.372  -0.999  -1.000  -0.927
105   I        -1.332  -1.329  -1.282  -1.401  -1.388  -1.332  -0.999  -0.995  -0.922
106   L        -0.941  -0.946  -0.908  -1.073  -1.082  -1.004  -0.828  -0.832  -0.767
107   N        -1.332  -1.313  -1.284  -0.796  -0.769  -0.711  -0.999  -0.981  -0.924
108   L        -0.401  -0.413  -0.409  -0.560  -0.582  -0.574  -0.487  -0.495  -0.475
109   C         0.235   0.246   0.207   0.363   0.394   0.305   0.025   0.048  -0.015
110   Y         2.126   2.130   2.232   2.304   2.310   2.473   2.413   2.418   2.594
111   K        -0.401  -0.421  -0.420  -0.172  -0.199  -0.184  -0.487  -0.509  -0.491
112   H        -1.724  -1.723  -1.645  -1.240  -1.239  -1.114  -1.169  -1.167  -1.069
113   E        -1.332  -1.352  -1.309  -1.175  -1.218  -1.176  -0.999  -1.015  -0.945
114   W        -0.941  -0.938  -0.902  -0.824  -0.820  -0.740  -0.828  -0.825  -0.762
115   S        -1.332  -1.313  -1.284  -1.303  -1.279  -1.222  -0.999  -0.981  -0.924
116   S         0.775   0.782   0.863   0.451   0.459   0.590   0.366   0.379   0.482
117   T         0.235   0.255   0.209   0.094   0.138   0.051   0.025   0.060  -0.012
118   F        -0.401  -0.380  -0.400  -0.317  -0.283  -0.309  -0.487  -0.461  -0.469
119   L         0.551   0.578   0.371   0.469   0.507   0.201   0.537   0.577   0.250
120   I         0.235   0.226   0.189   0.068   0.053  -0.005   0.025   0.011  -0.049
121   S        -0.009  -0.006   0.066  -0.309  -0.308  -0.182  -0.316  -0.313  -0.222
122   L        -0.793  -0.799  -0.833  -0.839  -0.851  -0.890  -0.658  -0.665  -0.684
123   S         0.235   0.232   0.203   0.009   0.009  -0.071   0.025   0.025  -0.029
124   L         0.139   0.131   0.148  -0.054  -0.079  -0.058  -0.146  -0.154  -0.119
125   V        -0.401  -0.419  -0.418  -0.399  -0.431  -0.413  -0.487  -0.508  -0.491
126   L         1.315   1.312   1.180   1.199   1.194   1.004   1.390   1.384   1.122
127   I        -0.941  -0.933  -0.910  -0.926  -0.921  -0.856  -0.828  -0.821  -0.768
128   G         1.315   1.348   1.180   1.262   1.309   1.044   1.390   1.444   1.123
129   Y         0.551   0.548   0.359   0.721   0.718   0.450   0.537   0.533   0.233
130   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
131   S         1.315   1.319   1.171   1.159   1.164   0.939   1.390   1.396   1.105
132   V        -0.941  -0.947  -0.924  -0.931  -0.933  -0.885  -0.828  -0.833  -0.780
133   S        -1.332  -1.321  -1.297  -1.185  -1.166  -1.170  -0.999  -0.989  -0.935
134   G         0.139   0.131   0.153  -0.318  -0.326  -0.283  -0.146  -0.154  -0.113
135   F         0.942   0.975   0.973   0.889   0.943   0.926   0.707   0.769   0.714
136   Y        -0.549  -0.548  -0.494  -0.648  -0.645  -0.558  -0.658  -0.656  -0.575
137   A         0.942   0.961   0.942   0.710   0.743   0.648   0.707   0.743   0.648
138   S        -0.009   0.001   0.071  -0.417  -0.408  -0.300  -0.316  -0.303  -0.215
139   V        -0.401  -0.376  -0.405  -0.469  -0.425  -0.476  -0.487  -0.457  -0.475
140   K         2.126   2.130   2.232   2.372   2.378   2.542   2.413   2.418   2.594
141   C        -0.401  -0.400  -0.406  -0.243  -0.230  -0.244  -0.487  -0.481  -0.472
142   A        -0.549  -0.535  -0.484  -0.708  -0.686  -0.604  -0.658  -0.645  -0.566
143   N        -0.401  -0.406  -0.423  -0.298  -0.306  -0.303  -0.487  -0.488  -0.493
144   T        -0.941  -0.931  -0.905  -1.222  -1.208  -1.166  -0.828  -0.819  -0.764
145   N         1.315   1.291   1.170   1.670   1.641   1.492   1.390   1.348   1.103
146   F         0.551   0.532   0.356   0.772   0.750   0.526   0.537   0.508   0.228
147   P         2.126   2.130   2.232   2.377   2.382   2.547   2.413   2.418   2.594
148   Q        -1.724  -1.723  -1.645  -0.971  -0.965  -0.841  -1.169  -1.167  -1.069
149   H         0.235   0.226   0.195   0.500   0.482   0.426   0.025   0.007  -0.041
150   R         1.315   1.348   1.180   1.694   1.737   1.524   1.390   1.444   1.123
151   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
152   T        -0.401  -0.391  -0.407  -0.512  -0.495  -0.550  -0.487  -0.473  -0.477
153   A         2.126   2.130   2.232   2.134   2.137   2.301   2.413   2.418   2.594
154   G         0.139   0.138   0.157  -0.129  -0.125  -0.104  -0.146  -0.146  -0.108
155   A         0.235   0.259   0.211   0.073   0.100   0.043   0.025   0.055  -0.013
156   F         0.139   0.142   0.165  -0.075  -0.070  -0.023  -0.146  -0.143  -0.099
157   P         2.126   2.130   2.232   2.377   2.382   2.547   2.413   2.418   2.594
158   V        -0.401  -0.420  -0.421  -0.512  -0.549  -0.536  -0.487  -0.509  -0.493
159   S         0.775   0.786   0.865   0.330   0.354   0.457   0.366   0.387   0.487
160   L        -0.157  -0.158  -0.299  -0.058  -0.060  -0.284  -0.146  -0.147  -0.327
161   Y         0.775   0.776   0.859   0.596   0.597   0.723   0.366   0.366   0.474
162   G         1.315   1.291   1.170   1.295   1.263   1.085   1.390   1.348   1.103
163   L         1.315   1.344   1.185   1.206   1.244   1.024   1.390   1.438   1.131
164   S         1.315   1.344   1.185   1.172   1.211   0.985   1.390   1.438   1.131
165   G         1.315   1.311   1.176   1.361   1.354   1.151   1.390   1.383   1.116
166   M        -0.009  -0.001   0.067  -0.073  -0.058   0.050  -0.316  -0.305  -0.220
167   V        -0.549  -0.549  -0.485  -0.803  -0.804  -0.714  -0.658  -0.657  -0.567
168   F         1.315   1.291   1.170   1.442   1.411   1.252   1.390   1.348   1.103
169   S         2.126   2.130   2.232   1.933   1.938   2.098   2.413   2.418   2.594
170   Y        -0.401  -0.384  -0.407  -0.408  -0.379  -0.419  -0.487  -0.467  -0.477
171   L         0.235   0.221   0.188  -0.054  -0.077  -0.188   0.025   0.006  -0.053
172   C        -0.941  -0.942  -0.912  -1.156  -1.152  -1.079  -0.828  -0.829  -0.770
173   S        -0.401  -0.406  -0.403  -0.714  -0.718  -0.712  -0.487  -0.487  -0.468
174   K        -0.157  -0.178  -0.300   0.072   0.041  -0.153  -0.146  -0.173  -0.328
175   L        -0.549  -0.557  -0.487  -0.778  -0.789  -0.686  -0.658  -0.664  -0.569
176   F         1.315   1.319   1.171   1.442   1.448   1.253   1.390   1.396   1.105
177   G        -0.401  -0.408  -0.418  -0.164  -0.175  -0.186  -0.487  -0.496  -0.488
178   E         0.235   0.233   0.192   0.212   0.211   0.182   0.025   0.022  -0.047
179   N        -0.157  -0.151  -0.291   0.278   0.287   0.090  -0.146  -0.139  -0.317
180   I        -0.401  -0.394  -0.419  -0.431  -0.408  -0.469  -0.487  -0.477  -0.491
181   E        -0.793  -0.814  -0.852  -0.809  -0.846  -0.910  -0.658  -0.681  -0.703
182   H        -1.332  -1.339  -1.288  -1.039  -1.046  -0.943  -0.999  -1.004  -0.927
183   V         0.551   0.570   0.375   0.642   0.672   0.355   0.537   0.566   0.257
184   F         0.942   0.928   0.945   0.634   0.607   0.612   0.707   0.677   0.654
185   I        -1.332  -1.326  -1.288  -1.015  -1.012  -0.924  -0.999  -0.993  -0.928
186   F         0.551   0.549   0.366   0.630   0.627   0.322   0.537   0.534   0.244
187   L         2.126   2.130   2.232   1.960   1.964   2.125   2.413   2.418   2.594
188   M        -0.941  -0.954  -0.903  -1.080  -1.099  -1.003  -0.828  -0.839  -0.763
189   V        -0.401  -0.391  -0.407  -0.545  -0.528  -0.575  -0.487  -0.473  -0.477
190   A        -1.332  -1.352  -1.309  -1.588  -1.640  -1.614  -0.999  -1.015  -0.945
191   C         0.235   0.229   0.191   0.471   0.458   0.404   0.025   0.013  -0.045
192   G        -0.793  -0.821  -0.854  -0.808  -0.851  -0.913  -0.658  -0.688  -0.706
193   C        -0.793  -0.822  -0.862  -0.860  -0.902  -0.946  -0.658  -0.689  -0.714
194   M         0.235   0.268   0.196   0.071   0.117   0.028   0.025   0.072  -0.039
195   I        -0.401  -0.409  -0.420  -0.567  -0.586  -0.644  -0.487  -0.498  -0.491
196   L        -0.009  -0.015   0.055  -0.378  -0.395  -0.305  -0.316  -0.326  -0.238
197   V        -0.401  -0.378  -0.412  -0.589  -0.552  -0.627  -0.487  -0.461  -0.484
198   G         1.315   1.312   1.180   1.266   1.263   1.051   1.390   1.384   1.122
199   Y        -1.332  -1.352  -1.309  -1.474  -1.500  -1.418  -0.999  -1.015  -0.945
200   F        -0.793  -0.792  -0.826  -0.541  -0.544  -0.574  -0.658  -0.656  -0.676
201   S         0.235   0.225   0.187   0.064   0.039  -0.033   0.025   0.007  -0.050
202   L        -0.401  -0.405  -0.409  -0.589  -0.603  -0.623  -0.487  -0.493  -0.480
203   D        -0.505  -0.513  -0.466  -0.188  -0.200  -0.110  -0.605  -0.614  -0.544
204   I         0.139   0.143   0.154  -0.015  -0.007   0.040  -0.146  -0.141  -0.112
205   F        -0.793  -0.814  -0.852  -0.591  -0.622  -0.714  -0.658  -0.681  -0.703
206   S        -0.157  -0.116  -0.294   0.108   0.171  -0.149  -0.146  -0.092  -0.321
207   N        -1.332  -1.340  -1.286  -0.809  -0.819  -0.728  -0.999  -1.005  -0.926
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -         0.069   0.028   0.085  -0.008  -0.097  -0.039  -0.199  -0.262  -0.193
211   -         0.069   0.064   0.114  -0.132  -0.137  -0.050  -0.199  -0.208  -0.149
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -         0.069   0.123   0.119   0.103   0.203   0.170  -0.199  -0.116  -0.142
215   -        -0.617  -0.611  -0.530  -0.353  -0.337  -0.216  -0.722  -0.715  -0.611
216   -         1.014   1.059   1.017   1.191   1.265   1.184   0.846   0.932   0.802
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -0.505  -0.498  -0.460  -0.589  -0.582  -0.511  -0.605  -0.597  -0.537
219   -        -1.419  -1.415  -1.338  -1.051  -1.037  -0.923  -1.070  -1.066  -0.968
220   -         0.125   0.092   0.135   0.015  -0.024   0.064  -0.141  -0.181  -0.129
221   A        -0.401  -0.394  -0.397  -0.655  -0.655  -0.633  -0.487  -0.481  -0.466
222   E        -0.332  -0.360  -0.394  -0.064  -0.110  -0.176  -0.373  -0.409  -0.449
223   G         0.410   0.479   0.300   0.476   0.568   0.340   0.323   0.428   0.140
224   D        -0.962  -0.939  -0.914  -0.944  -0.920  -0.851  -0.838  -0.814  -0.767
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   D        -0.510  -0.499  -0.467  -0.213  -0.193  -0.146  -0.596  -0.583  -0.538
263   A         0.795   0.792   0.872   0.728   0.717   0.833   0.407   0.399   0.502
264   S        -0.510  -0.469  -0.462  -0.576  -0.517  -0.509  -0.596  -0.546  -0.532
265   I        -0.510  -0.469  -0.462  -0.386  -0.318  -0.324  -0.596  -0.546  -0.532
266   K        -0.510  -0.541  -0.493  -0.480  -0.536  -0.461  -0.596  -0.633  -0.569
267   E        -1.058  -1.054  -0.974  -1.060  -1.069  -0.931  -0.931  -0.926  -0.825
268   W        -1.058  -1.054  -0.974  -0.791  -0.804  -0.659  -0.931  -0.926  -0.825
269   E         0.039   0.044   0.094  -0.345  -0.329  -0.231  -0.262  -0.254  -0.186
270   L        -0.510  -0.496  -0.480  -0.727  -0.713  -0.672  -0.596  -0.580  -0.554
271   Q        -0.510  -0.524  -0.466  -0.449  -0.482  -0.401  -0.596  -0.614  -0.536
272   K         0.039   0.032   0.100   0.144   0.136   0.243  -0.262  -0.270  -0.180
273   S        -0.510  -0.524  -0.466  -0.820  -0.827  -0.751  -0.596  -0.614  -0.536
274   R         0.246   0.234   0.189   0.148   0.129   0.086   0.073   0.054  -0.033
275   E        -1.058  -1.054  -0.974  -0.834  -0.838  -0.702  -0.931  -0.926  -0.825
276   T        -0.510  -0.499  -0.467  -0.644  -0.616  -0.579  -0.596  -0.583  -0.538
277   D        -0.510  -0.515  -0.461  -0.634  -0.635  -0.543  -0.596  -0.603  -0.531
278   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   E         0.069   0.051   0.085  -0.092  -0.112  -0.027  -0.199  -0.226  -0.193
297   N        -0.510  -0.496  -0.480  -0.602  -0.582  -0.602  -0.596  -0.580  -0.554
298   S        -0.332  -0.287  -0.370  -0.408  -0.356  -0.444  -0.373  -0.315  -0.418
299   N         0.125   0.103   0.129  -0.088  -0.123  -0.097  -0.141  -0.171  -0.137
300   D         0.410   0.386   0.284   0.515   0.487   0.352   0.323   0.287   0.115
301   Y        -0.505  -0.486  -0.457  -0.315  -0.281  -0.244  -0.605  -0.586  -0.534
302   I        -1.419  -1.416  -1.338  -1.195  -1.199  -1.069  -1.070  -1.067  -0.968
303   G        -0.505  -0.516  -0.458  -0.397  -0.423  -0.347  -0.605  -0.616  -0.535
304   S        -0.962  -0.963  -0.919  -0.804  -0.803  -0.737  -0.838  -0.838  -0.773
305   P         0.410   0.374   0.289   0.727   0.675   0.545   0.323   0.269   0.122
306   V        -0.332  -0.324  -0.363  -0.182  -0.165  -0.275  -0.373  -0.363  -0.409
307   R        -0.505  -0.492  -0.459  -0.483  -0.464  -0.388  -0.605  -0.592  -0.536
308   S         0.410   0.374   0.289   0.307   0.259   0.141   0.323   0.269   0.122
309   S        -1.419  -1.416  -1.338  -1.357  -1.337  -1.233  -1.070  -1.067  -0.968
310   S         0.125   0.108   0.144  -0.135  -0.154  -0.083  -0.141  -0.162  -0.117
311   P        -0.510  -0.496  -0.480  -0.630  -0.594  -0.639  -0.596  -0.580  -0.554
312   A        -1.058  -1.054  -0.974  -0.970  -0.963  -0.840  -0.931  -0.926  -0.825
313   T        -0.510  -0.469  -0.462  -0.474  -0.417  -0.398  -0.596  -0.546  -0.532
314   Y        -0.510  -0.541  -0.493  -0.645  -0.683  -0.583  -0.596  -0.633  -0.569
315   E         0.246   0.236   0.206   0.412   0.382   0.310   0.073   0.055  -0.007
316   T        -0.510  -0.499  -0.467  -0.738  -0.717  -0.698  -0.596  -0.583  -0.538
317   Y        -1.058  -1.054  -0.974  -1.143  -1.140  -1.015  -0.931  -0.926  -0.825
318   A         0.246   0.278   0.225   0.323   0.372   0.281   0.073   0.121   0.022
319   L        -0.510  -0.496  -0.480  -0.742  -0.727  -0.689  -0.596  -0.580  -0.554
320   S        -0.617  -0.611  -0.530  -0.842  -0.836  -0.711  -0.722  -0.715  -0.611
321   D         0.069   0.072   0.113   0.263   0.265   0.327  -0.199  -0.196  -0.150
322   N        -0.617  -0.611  -0.530  -0.836  -0.801  -0.705  -0.722  -0.715  -0.611
323   F         0.069   0.028   0.085  -0.301  -0.370  -0.290  -0.199  -0.261  -0.193
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   Q        -0.617  -0.611  -0.530  -0.364  -0.357  -0.227  -0.722  -0.715  -0.611
331   E         0.755   0.761   0.856   0.790   0.804   0.950   0.323   0.336   0.467
332   T         0.069   0.122   0.118   0.153   0.237   0.232  -0.199  -0.118  -0.143
333   S         0.246   0.307   0.208   0.096   0.182   0.058   0.073   0.166  -0.003
334   E         0.039   0.032   0.100  -0.108  -0.125  -0.006  -0.262  -0.270  -0.180
335   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   S        -0.332  -0.287  -0.370  -0.370  -0.312  -0.398  -0.373  -0.315  -0.418
351   P         0.410   0.418   0.302   0.654   0.659   0.466   0.323   0.335   0.143
352   S         1.235   1.207   1.133   1.116   1.081   0.987   1.252   1.203   1.033
353   S        -0.332  -0.298  -0.374  -0.575  -0.526  -0.656  -0.373  -0.330  -0.423
354   P         0.410   0.433   0.303   0.711   0.742   0.546   0.323   0.358   0.144
355   H        -0.510  -0.524  -0.465  -0.286  -0.298  -0.230  -0.596  -0.614  -0.535
356   T        -1.724  -1.723  -1.645  -1.502  -1.509  -1.379  -1.169  -1.167  -1.069
357   K         0.775   0.781   0.860   0.812   0.823   0.940   0.366   0.376   0.476
358   Y        -0.941  -0.942  -0.909  -0.802  -0.798  -0.765  -0.828  -0.829  -0.768
359   D        -0.941  -0.958  -0.924  -0.608  -0.636  -0.563  -0.828  -0.843  -0.780
360   F        -0.941  -0.952  -0.902  -1.060  -1.076  -0.989  -0.828  -0.837  -0.761
361   E        -0.793  -0.759  -0.834  -0.554  -0.495  -0.671  -0.658  -0.620  -0.685
362   D         0.410   0.385   0.287   0.576   0.531   0.315   0.323   0.285   0.120
363   E        -0.510  -0.498  -0.468  -0.351  -0.338  -0.265  -0.596  -0.581  -0.539
364   N        -0.941  -0.951  -0.901  -0.866  -0.878  -0.787  -0.828  -0.837  -0.761
365   T        -0.401  -0.409  -0.420  -0.282  -0.296  -0.274  -0.487  -0.498  -0.491
366   S         0.139   0.130   0.155  -0.003  -0.017   0.046  -0.146  -0.155  -0.111
367   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   N        -0.962  -0.966  -0.931  -0.913  -0.910  -0.825  -0.838  -0.842  -0.784
374   S        -0.962  -0.938  -0.919  -1.180  -1.141  -1.108  -0.838  -0.813  -0.772
375   A        -1.332  -1.318  -1.286  -1.406  -1.383  -1.322  -0.999  -0.985  -0.926
376   Q         0.235   0.240   0.209   0.105   0.113   0.103   0.025   0.035  -0.020
377   K        -0.401  -0.419  -0.418  -0.048  -0.071  -0.042  -0.487  -0.508  -0.491
378   S        -0.941  -0.946  -0.904  -0.751  -0.761  -0.661  -0.828  -0.832  -0.763
379   M        -0.962  -0.978  -0.931  -0.904  -0.928  -0.858  -0.838  -0.853  -0.784
380   R        -0.332  -0.353  -0.397  -0.026  -0.063  -0.141  -0.373  -0.400  -0.452
381   L         0.867   0.865   0.914   0.554   0.546   0.589   0.556   0.549   0.590
382   H        -0.332  -0.342  -0.383  -0.014  -0.029  -0.077  -0.373  -0.386  -0.434
383   V         0.125   0.119   0.133  -0.153  -0.167  -0.146  -0.141  -0.153  -0.134
384   F        -0.962  -0.946  -0.914  -0.783  -0.749  -0.720  -0.838  -0.821  -0.767
385   Q        -0.962  -0.956  -0.931  -0.788  -0.774  -0.764  -0.838  -0.831  -0.784
386   S         0.410   0.402   0.284   0.265   0.256   0.061   0.323   0.312   0.115
387   L        -0.332  -0.310  -0.363  -0.531  -0.496  -0.592  -0.373  -0.345  -0.409
388   K        -0.793  -0.772  -0.836  -0.430  -0.404  -0.506  -0.658  -0.635  -0.687
389   S         0.235   0.270   0.196   0.008   0.059  -0.044   0.025   0.076  -0.038
390   S        -1.332  -1.329  -1.282  -1.433  -1.443  -1.346  -0.999  -0.995  -0.922
391   T        -1.332  -1.321  -1.283  -0.931  -0.904  -0.856  -0.999  -0.988  -0.924
392   F         2.126   2.130   2.232   2.174   2.178   2.341   2.413   2.418   2.594
393   I        -0.793  -0.777  -0.854  -0.499  -0.467  -0.666  -0.658  -0.640  -0.706
394   G        -1.332  -1.329  -1.299  -1.154  -1.149  -1.129  -0.999  -0.995  -0.937
395   Y         0.235   0.211   0.185   0.430   0.387   0.317   0.025  -0.012  -0.053
396   Y         0.775   0.776   0.859   0.596   0.597   0.723   0.366   0.366   0.474
397   I        -0.793  -0.789  -0.825  -0.796  -0.790  -0.826  -0.658  -0.654  -0.675
398   V         0.942   0.928   0.945   0.791   0.766   0.765   0.707   0.677   0.654
399   L        -0.549  -0.548  -0.494  -0.683  -0.685  -0.594  -0.658  -0.656  -0.575
400   G        -0.401  -0.413  -0.409  -0.642  -0.645  -0.626  -0.487  -0.495  -0.475
401   I        -0.157  -0.138  -0.276  -0.080  -0.045  -0.269  -0.146  -0.121  -0.298
402   L        -0.401  -0.365  -0.407  -0.678  -0.628  -0.677  -0.487  -0.447  -0.475
403   Q        -0.009  -0.001   0.067  -0.282  -0.259  -0.164  -0.316  -0.305  -0.220
404   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
405   V        -0.157  -0.185  -0.310  -0.024  -0.063  -0.245  -0.146  -0.183  -0.342
406   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
407   L         0.942   0.933   0.931   0.970   0.949   0.879   0.707   0.686   0.626
408   M         2.126   2.130   2.232   2.431   2.436   2.602   2.413   2.418   2.594
409   Y         0.551   0.538   0.344   0.823   0.807   0.509   0.537   0.518   0.209
410   I         2.126   2.130   2.232   2.115   2.122   2.282   2.413   2.418   2.594
411   Y         1.315   1.300   1.170   1.585   1.568   1.402   1.390   1.364   1.103
412   S         0.551   0.532   0.356   0.459   0.434   0.179   0.537   0.508   0.228
413   V         0.235   0.222   0.192   0.283   0.263   0.219   0.025   0.007  -0.043
414   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
415   F         0.551   0.532   0.356   0.764   0.741   0.513   0.537   0.508   0.228
416   M        -1.332  -1.352  -1.309  -1.316  -1.347  -1.281  -0.999  -1.015  -0.945
417   V         1.315   1.312   1.180   1.429   1.425   1.232   1.390   1.384   1.122
418   Q        -0.941  -0.951  -0.900  -0.584  -0.594  -0.500  -0.828  -0.836  -0.760
419   A         1.315   1.291   1.170   1.341   1.304   1.105   1.390   1.348   1.103
420   Q         0.139   0.125   0.147   0.037   0.015   0.085  -0.146  -0.161  -0.121
421   V        -0.962  -0.953  -0.931  -0.727  -0.702  -0.664  -0.838  -0.828  -0.784
422   S        -1.419  -1.416  -1.338  -1.174  -1.168  -1.046  -1.070  -1.067  -0.968
423   T         0.410   0.386   0.295   0.673   0.643   0.501   0.323   0.288   0.132
424   P        -1.419  -1.416  -1.338  -1.340  -1.345  -1.215  -1.070  -1.067  -0.968
425   P        -0.505  -0.522  -0.459  -0.252  -0.272  -0.168  -0.605  -0.622  -0.537
426   L        -0.962  -0.969  -0.914  -1.098  -1.105  -1.014  -0.838  -0.845  -0.767
427   N        -0.941  -0.946  -0.908  -0.736  -0.748  -0.673  -0.828  -0.832  -0.767
428   Q        -1.332  -1.318  -1.286  -1.222  -1.204  -1.138  -0.999  -0.985  -0.926
429   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
430   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
431   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
432   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
433   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
434   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
435   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
436   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
437   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
438   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
439   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
440   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
441   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
442   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
443   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
444   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
445   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
446   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
447   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
448   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
449   L        -1.724  -1.723  -1.645  -1.506  -1.510  -1.383  -1.169  -1.167  -1.069
450   P        -0.793  -0.792  -0.838  -0.433  -0.438  -0.517  -0.658  -0.657  -0.689
451   I        -1.724  -1.723  -1.645  -1.316  -1.321  -1.190  -1.169  -1.167  -1.069
452   N        -1.332  -1.317  -1.299  -1.007  -0.975  -0.966  -0.999  -0.985  -0.937
453   A        -0.941  -0.938  -0.911  -1.232  -1.228  -1.190  -0.828  -0.825  -0.769
454   E        -0.793  -0.771  -0.832  -0.485  -0.451  -0.582  -0.658  -0.633  -0.683
455   K        -1.332  -1.331  -1.283  -1.021  -1.013  -0.938  -0.999  -0.997  -0.923
456   I        -0.401  -0.420  -0.427  -0.606  -0.632  -0.612  -0.487  -0.511  -0.499
457   Q         2.126   2.130   2.232   2.392   2.398   2.562   2.413   2.418   2.594
458   S         0.235   0.246   0.207  -0.032  -0.007  -0.049   0.025   0.048  -0.015
459   L        -0.157  -0.194  -0.304  -0.196  -0.249  -0.407  -0.146  -0.194  -0.333
460   Q         0.942   0.933   0.948   1.152   1.138   1.152   0.707   0.687   0.661
461   V         2.126   2.130   2.232   2.192   2.196   2.360   2.413   2.418   2.594
462   T        -0.401  -0.409  -0.420  -0.680  -0.691  -0.710  -0.487  -0.498  -0.491
463   L        -0.941  -0.930  -0.899  -1.087  -1.069  -1.007  -0.828  -0.818  -0.758
464   L         0.775   0.770   0.855   0.331   0.315   0.431   0.366   0.353   0.466
465   S         2.126   2.130   2.232   1.933   1.938   2.098   2.413   2.418   2.594
466   L         0.139   0.160   0.157  -0.221  -0.197  -0.175  -0.146  -0.123  -0.109
467   L        -0.941  -0.944  -0.903  -1.306  -1.313  -1.265  -0.828  -0.831  -0.763
468   S         2.126   2.130   2.232   1.933   1.938   2.098   2.413   2.418   2.594
469   F         2.126   2.130   2.232   2.174   2.178   2.341   2.413   2.418   2.594
470   C        -0.941  -0.924  -0.900  -1.044  -1.017  -1.000  -0.828  -0.813  -0.759
471   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
472   R         2.126   2.130   2.232   2.417   2.421   2.587   2.413   2.418   2.594
473   L         0.942   0.961   0.942   0.611   0.643   0.575   0.707   0.743   0.648
474   S        -1.332  -1.321  -1.297  -1.637  -1.617  -1.594  -0.999  -0.989  -0.935
475   S         2.126   2.130   2.232   1.933   1.938   2.098   2.413   2.418   2.594
476   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
477   P        -1.332  -1.352  -1.309  -1.214  -1.244  -1.177  -0.999  -1.015  -0.945
478   I         0.139   0.131   0.148  -0.271  -0.276  -0.253  -0.146  -0.154  -0.119
479   S         1.315   1.319   1.171   1.226   1.231   1.056   1.390   1.396   1.105
480   D         2.126   2.130   2.232   2.390   2.395   2.560   2.413   2.418   2.594
481   F        -0.157  -0.138  -0.276  -0.051  -0.024  -0.253  -0.146  -0.121  -0.298
482   L         0.235   0.261   0.208  -0.080  -0.034  -0.125   0.025   0.068  -0.014
483   V        -0.401  -0.388  -0.407  -0.368  -0.347  -0.373  -0.487  -0.467  -0.473
484   K         0.551   0.549   0.366   0.879   0.878   0.594   0.537   0.534   0.244
485   K        -0.332  -0.335  -0.367  -0.014  -0.019  -0.066  -0.373  -0.377  -0.414
486   F        -0.941  -0.948  -0.899  -0.814  -0.827  -0.774  -0.828  -0.834  -0.759
487   K        -0.549  -0.535  -0.485  -0.229  -0.214  -0.117  -0.658  -0.645  -0.567
488   A        -0.941  -0.950  -0.913  -1.005  -1.021  -0.949  -0.828  -0.836  -0.770
489   Q        -0.401  -0.420  -0.421  -0.264  -0.296  -0.273  -0.487  -0.509  -0.493
490   R         1.315   1.319   1.171   1.625   1.631   1.391   1.390   1.396   1.105
491   L         1.315   1.300   1.170   1.210   1.188   1.006   1.390   1.364   1.103
492   W         1.315   1.319   1.171   1.713   1.720   1.482   1.390   1.396   1.105
493   N        -0.941  -0.947  -0.924  -0.769  -0.764  -0.721  -0.828  -0.833  -0.780
494   I         0.235   0.246   0.207   0.062   0.087  -0.002   0.025   0.048  -0.015
495   V        -0.157  -0.144  -0.275  -0.020  -0.006  -0.193  -0.146  -0.129  -0.296
496   I        -0.332  -0.303  -0.386  -0.477  -0.428  -0.609  -0.373  -0.336  -0.439
497   A        -0.549  -0.553  -0.496  -0.880  -0.893  -0.810  -0.658  -0.660  -0.577
498   S        -0.941  -0.937  -0.900  -1.333  -1.329  -1.265  -0.828  -0.825  -0.760
499   L        -0.549  -0.558  -0.487  -0.859  -0.872  -0.764  -0.658  -0.665  -0.569
500   L        -0.401  -0.379  -0.412  -0.700  -0.669  -0.715  -0.487  -0.462  -0.484
501   V        -1.332  -1.336  -1.287  -1.551  -1.557  -1.515  -0.999  -1.001  -0.927
502   F        -0.941  -0.950  -0.913  -1.101  -1.118  -1.070  -0.828  -0.836  -0.770
503   L        -0.401  -0.397  -0.394  -0.557  -0.546  -0.533  -0.487  -0.481  -0.462
504   A         0.139   0.160   0.158  -0.086  -0.063  -0.023  -0.146  -0.122  -0.108
505   S         0.775   0.771   0.859   0.553   0.537   0.655   0.366   0.357   0.474
506   N        -0.617  -0.615  -0.530  -0.762  -0.763  -0.630  -0.722  -0.719  -0.611
507   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
508   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
509   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
510   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
511   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
512   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
513   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
514   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
515   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
516   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
517   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
518   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
519   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
520   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
521   P        -0.401  -0.405  -0.397  -0.579  -0.581  -0.565  -0.487  -0.490  -0.466
522   S        -0.941  -0.935  -0.909  -1.231  -1.222  -1.156  -0.828  -0.823  -0.768
523   L        -0.157  -0.116  -0.294  -0.138  -0.078  -0.389  -0.146  -0.092  -0.321
524   R        -1.332  -1.324  -1.293  -1.281  -1.273  -1.197  -0.999  -0.991  -0.932
525   A        -0.793  -0.814  -0.852  -0.534  -0.569  -0.667  -0.658  -0.681  -0.703
526   S        -0.793  -0.804  -0.841  -0.868  -0.895  -1.012  -0.658  -0.670  -0.692
527   K        -0.793  -0.826  -0.861  -0.533  -0.593  -0.684  -0.658  -0.693  -0.713
528   S        -0.941  -0.919  -0.907  -0.612  -0.586  -0.560  -0.828  -0.809  -0.765
529   F        -1.332  -1.331  -1.283  -1.287  -1.289  -1.195  -0.999  -0.997  -0.923
530   K        -0.793  -0.797  -0.834  -0.427  -0.429  -0.522  -0.658  -0.662  -0.685
531   N        -0.401  -0.420  -0.416  -0.467  -0.489  -0.450  -0.487  -0.508  -0.489
532   I        -0.401  -0.387  -0.408  -0.636  -0.620  -0.648  -0.487  -0.474  -0.477
533   S        -1.332  -1.329  -1.299  -0.980  -0.980  -0.954  -0.999  -0.995  -0.937
534   V        -0.549  -0.550  -0.486  -0.671  -0.673  -0.582  -0.658  -0.658  -0.568
535   C        -0.793  -0.777  -0.854  -0.672  -0.653  -0.785  -0.658  -0.640  -0.706
536   S         2.126   2.130   2.232   1.933   1.938   2.098   2.413   2.418   2.594
537   A        -0.401  -0.399  -0.399  -0.678  -0.685  -0.697  -0.487  -0.487  -0.469
538   I         0.551   0.542   0.366   0.404   0.390   0.092   0.537   0.523   0.244
539   F        -0.549  -0.535  -0.486  -0.878  -0.862  -0.771  -0.658  -0.645  -0.568
540   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
541   Y         0.235   0.255   0.209  -0.067  -0.028  -0.094   0.025   0.060  -0.012
542   S        -0.793  -0.799  -0.833  -0.816  -0.829  -0.854  -0.658  -0.665  -0.684
543   F         0.942   0.928   0.945   0.963   0.937   0.930   0.707   0.677   0.654
544   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
545   V        -0.549  -0.549  -0.489  -0.878  -0.870  -0.774  -0.658  -0.657  -0.571
546   L        -0.549  -0.557  -0.490  -0.704  -0.713  -0.617  -0.658  -0.664  -0.572
547   F         1.315   1.312   1.180   1.442   1.439   1.266   1.390   1.384   1.122
548   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
549   T        -0.401  -0.385  -0.408  -0.402  -0.385  -0.417  -0.487  -0.471  -0.477
550   F         0.775   0.770   0.855   0.622   0.609   0.730   0.366   0.353   0.466
551   P         2.126   2.130   2.232   2.377   2.382   2.547   2.413   2.418   2.594
552   S        -0.549  -0.557  -0.490  -0.911  -0.931  -0.843  -0.658  -0.664  -0.572
553   I         1.315   1.344   1.185   1.365   1.406   1.184   1.390   1.438   1.131
554   V         0.139   0.143   0.152  -0.118  -0.110  -0.103  -0.146  -0.141  -0.114
555   A         2.126   2.130   2.232   2.134   2.137   2.301   2.413   2.418   2.594
556   D         0.942   0.933   0.948   1.139   1.123   1.136   0.707   0.687   0.661
557   R        -0.941  -0.940  -0.905  -0.771  -0.779  -0.684  -0.828  -0.827  -0.764
558   F         1.315   1.319   1.171   1.442   1.448   1.253   1.390   1.396   1.105
559   G         1.315   1.291   1.170   1.262   1.227   1.026   1.390   1.348   1.103
560   T        -0.401  -0.427  -0.422  -0.220  -0.254  -0.236  -0.487  -0.516  -0.493
561   N        -1.332  -1.321  -1.283  -0.767  -0.750  -0.679  -0.999  -0.988  -0.924
562   G        -0.941  -0.919  -0.898  -0.908  -0.868  -0.849  -0.828  -0.809  -0.757
563   Y         0.235   0.211   0.185   0.170   0.129   0.070   0.025  -0.012  -0.053
564   S         2.126   2.130   2.232   1.933   1.938   2.098   2.413   2.418   2.594
565   T         0.775   0.774   0.862   0.708   0.707   0.842   0.366   0.362   0.480
566   L        -0.793  -0.777  -0.854  -0.647  -0.617  -0.818  -0.658  -0.640  -0.706
567   W         2.126   2.130   2.232   2.501   2.506   2.672   2.413   2.418   2.594
568   G         2.126   2.130   2.232   2.056   2.061   2.222   2.413   2.418   2.594
569   V        -0.157  -0.178  -0.300  -0.210  -0.242  -0.421  -0.146  -0.173  -0.328
570   L        -0.793  -0.771  -0.832  -0.920  -0.883  -0.988  -0.658  -0.633  -0.683
571   T        -0.401  -0.388  -0.407  -0.355  -0.335  -0.392  -0.487  -0.467  -0.473
572   T         0.235   0.226   0.189   0.072   0.053  -0.060   0.025   0.011  -0.049
573   G         0.235   0.229   0.191  -0.076  -0.092  -0.176   0.025   0.013  -0.045
574   G         0.235   0.220   0.191   0.283   0.251   0.183   0.025  -0.000  -0.044
575   V        -0.793  -0.772  -0.836  -0.694  -0.663  -0.782  -0.658  -0.635  -0.687
576   F        -0.009   0.004   0.076  -0.260  -0.234  -0.134  -0.316  -0.298  -0.207
577   S        -0.401  -0.401  -0.409  -0.604  -0.607  -0.600  -0.487  -0.482  -0.475
578   V        -0.941  -0.947  -0.924  -1.274  -1.279  -1.270  -0.828  -0.833  -0.780
579   S        -0.793  -0.806  -0.841  -0.427  -0.447  -0.490  -0.658  -0.672  -0.692
580   V        -0.793  -0.759  -0.834  -0.640  -0.585  -0.712  -0.658  -0.620  -0.685
581   F         0.775   0.773   0.859   0.336   0.331   0.462   0.366   0.359   0.474
582   T         0.235   0.212   0.186   0.328   0.288   0.211   0.025  -0.008  -0.054
583   D        -0.941  -0.954  -0.919  -0.815  -0.836  -0.761  -0.828  -0.839  -0.776
584   I        -1.332  -1.317  -1.299  -1.216  -1.188  -1.155  -0.999  -0.985  -0.937
585   L        -0.009  -0.018   0.058  -0.285  -0.305  -0.194  -0.316  -0.330  -0.234
586   G         1.315   1.291   1.170   1.262   1.227   1.026   1.390   1.348   1.103
587   R        -0.157  -0.158  -0.299   0.175   0.171  -0.062  -0.146  -0.147  -0.327
588   D        -0.793  -0.777  -0.854  -0.642  -0.609  -0.747  -0.658  -0.640  -0.706
589   F         0.139   0.125   0.151   0.121   0.105   0.171  -0.146  -0.160  -0.115
590   K         0.551   0.523   0.344   0.936   0.897   0.634   0.537   0.495   0.208
591   A        -0.549  -0.535  -0.486  -0.678  -0.660  -0.555  -0.658  -0.645  -0.568
592   N         0.775   0.774   0.862   0.859   0.857   0.993   0.366   0.362   0.480
593   T         0.235   0.225   0.193  -0.046  -0.058  -0.111   0.025   0.016  -0.045
594   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
595   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
596   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
597   G         0.125   0.103   0.135   0.153   0.119   0.173  -0.141  -0.170  -0.129
598   D        -0.332  -0.371  -0.391  -0.316  -0.363  -0.356  -0.373  -0.422  -0.445
599   D        -0.549  -0.557  -0.486  -0.505  -0.519  -0.399  -0.658  -0.664  -0.569
600   D        -0.941  -0.942  -0.912  -0.737  -0.733  -0.689  -0.828  -0.829  -0.770
601   G        -0.401  -0.422  -0.421  -0.306  -0.329  -0.288  -0.487  -0.512  -0.492
602   N        -0.401  -0.421  -0.423  -0.425  -0.453  -0.435  -0.487  -0.511  -0.497
603   C         2.126   2.130   2.232   2.436   2.441   2.607   2.413   2.418   2.594
604   K        -0.401  -0.419  -0.423  -0.209  -0.235  -0.222  -0.487  -0.509  -0.497
605   K        -1.332  -1.341  -1.288  -1.013  -1.019  -0.906  -0.999  -1.006  -0.928
606   G         1.315   1.291   1.170   1.262   1.227   1.026   1.390   1.348   1.103
607   V        -0.941  -0.935  -0.900  -0.880  -0.877  -0.813  -0.828  -0.823  -0.760
608   L        -1.332  -1.336  -1.287  -1.065  -1.065  -1.009  -0.999  -1.001  -0.927
609   C         2.126   2.130   2.232   2.436   2.441   2.607   2.413   2.418   2.594
610   Y         2.126   2.130   2.232   2.304   2.310   2.473   2.413   2.418   2.594
611   S        -0.401  -0.403  -0.407  -0.167  -0.170  -0.176  -0.487  -0.489  -0.479
612   Y        -0.941  -0.942  -0.912  -0.855  -0.846  -0.789  -0.828  -0.829  -0.770
613   T         0.942   0.928   0.945   0.829   0.801   0.809   0.707   0.677   0.654
614   F         1.315   1.300   1.170   1.442   1.423   1.252   1.390   1.364   1.103
615   M        -1.332  -1.332  -1.284  -0.753  -0.753  -0.664  -0.999  -0.998  -0.924
616   V        -0.401  -0.424  -0.426  -0.490  -0.520  -0.505  -0.487  -0.514  -0.498
617   T         0.139   0.139   0.152  -0.169  -0.161  -0.131  -0.146  -0.145  -0.114
618   K        -0.401  -0.418  -0.410  -0.541  -0.567  -0.555  -0.487  -0.505  -0.481
619   Y        -0.941  -0.944  -0.903  -1.000  -1.011  -0.962  -0.828  -0.831  -0.763
620   C        -0.941  -0.958  -0.911  -0.967  -0.986  -0.902  -0.828  -0.842  -0.768
621   A        -0.401  -0.412  -0.416  -0.247  -0.272  -0.294  -0.487  -0.501  -0.489
622   A        -0.157  -0.132  -0.296  -0.164  -0.130  -0.431  -0.146  -0.114  -0.324
623   F        -1.724  -1.723  -1.645  -1.597  -1.599  -1.475  -1.169  -1.167  -1.069
624   N        -1.724  -1.723  -1.645  -1.623  -1.622  -1.501  -1.169  -1.167  -1.069
625   L        -0.157  -0.138  -0.276  -0.255  -0.228  -0.446  -0.146  -0.121  -0.298
626   L        -0.401  -0.388  -0.400  -0.392  -0.373  -0.406  -0.487  -0.475  -0.468
627   F        -0.157  -0.185  -0.310   0.036  -0.009  -0.197  -0.146  -0.183  -0.342
628   V        -0.549  -0.553  -0.486  -0.765  -0.775  -0.683  -0.658  -0.660  -0.567
629   L         1.315   1.291   1.170   1.206   1.173   1.001   1.390   1.348   1.103
630   G        -1.332  -1.324  -1.293  -1.097  -1.076  -1.071  -0.999  -0.991  -0.932
631   I        -0.941  -0.936  -0.910  -1.046  -1.034  -0.974  -0.828  -0.823  -0.768
632   I         1.315   1.319   1.171   1.365   1.373   1.162   1.390   1.396   1.105
633   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
634   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
635   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
636   T         0.069   0.068   0.114   0.252   0.250   0.310  -0.199  -0.201  -0.149
637   Y         0.551   0.564   0.366   0.866   0.888   0.610   0.537   0.556   0.243
638   Y        -0.793  -0.795  -0.839  -0.362  -0.360  -0.431  -0.658  -0.660  -0.690
639   R        -0.793  -0.794  -0.822  -0.219  -0.220  -0.241  -0.658  -0.659  -0.672
640   R        -0.793  -0.786  -0.836  -0.489  -0.481  -0.590  -0.658  -0.650  -0.687
641   R         0.775   0.772   0.856   0.824   0.819   0.947   0.366   0.359   0.467
642   A        -0.793  -0.804  -0.841  -0.328  -0.347  -0.393  -0.658  -0.670  -0.692
643   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
644   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
645   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
646   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
647   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
648   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
649   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
650   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03795
Output conservation file - output/Q03795
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
