1     M         2.405   2.412   2.486   2.795   2.801   2.931   2.745   2.754   2.877
2     S        -0.285  -0.280  -0.340  -0.209  -0.199  -0.280  -0.276  -0.270  -0.339
3     T        -0.597  -0.588  -0.545  -0.753  -0.728  -0.672  -0.654  -0.643  -0.584
4     A         0.154   0.109   0.145  -0.063  -0.178  -0.148  -0.087  -0.155  -0.109
5     Q        -0.597  -0.588  -0.545  -0.791  -0.792  -0.711  -0.654  -0.643  -0.584
6     K         0.154   0.140   0.165   0.162   0.152   0.164  -0.087  -0.110  -0.080
7     A         0.904   0.914   0.975   0.502   0.482   0.584   0.479   0.497   0.578
8     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    D        -1.080  -1.077  -1.033  -1.013  -1.007  -0.936  -0.880  -0.875  -0.815
15    S        -0.480  -0.486  -0.461  -0.509  -0.523  -0.494  -0.518  -0.525  -0.487
16    C        -1.080  -1.077  -1.033  -0.707  -0.703  -0.626  -0.880  -0.875  -0.815
17    C         1.322   1.345   1.249   1.106   1.130   1.016   1.295   1.335   1.133
18    Q        -0.480  -0.489  -0.465  -0.428  -0.448  -0.414  -0.518  -0.528  -0.492
19    N        -1.475  -1.471  -1.431  -1.344  -1.331  -1.272  -1.031  -1.026  -0.969
20    A        -1.475  -1.471  -1.431  -1.235  -1.215  -1.162  -1.031  -1.026  -0.969
21    K         1.430   1.438   1.308   1.456   1.472   1.278   1.486   1.499   1.245
22    S        -0.285  -0.309  -0.373  -0.476  -0.523  -0.660  -0.276  -0.306  -0.380
23    T        -0.474  -0.477  -0.470  -0.527  -0.528  -0.508  -0.528  -0.529  -0.506
24    Q        -0.975  -0.993  -0.961  -0.725  -0.751  -0.696  -0.779  -0.797  -0.748
25    L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
26    K        -0.285  -0.309  -0.373  -0.361  -0.389  -0.513  -0.276  -0.306  -0.380
27    S        -0.474  -0.466  -0.461  -0.393  -0.378  -0.362  -0.528  -0.518  -0.497
28    L         0.215   0.195   0.219  -0.170  -0.201  -0.154  -0.024  -0.044  -0.019
29    S        -0.474  -0.475  -0.468  -0.306  -0.288  -0.262  -0.528  -0.526  -0.503
30    F        -1.475  -1.471  -1.431  -1.553  -1.568  -1.485  -1.031  -1.026  -0.969
31    V        -0.285  -0.282  -0.346  -0.450  -0.447  -0.518  -0.276  -0.271  -0.347
32    I        -0.474  -0.462  -0.462  -0.679  -0.653  -0.636  -0.528  -0.514  -0.498
33    G         2.405   2.412   2.486   2.746   2.752   2.882   2.745   2.754   2.877
34    A         0.026   0.031   0.087  -0.439  -0.450  -0.367  -0.276  -0.269  -0.196
35    V        -1.475  -1.471  -1.431  -1.254  -1.257  -1.181  -1.031  -1.026  -0.969
36    N        -0.975  -0.993  -0.961  -0.833  -0.853  -0.806  -0.779  -0.797  -0.748
37    G        -1.475  -1.471  -1.431  -1.405  -1.407  -1.334  -1.031  -1.026  -0.969
38    T        -0.975  -0.938  -0.966  -0.681  -0.619  -0.669  -0.779  -0.740  -0.753
39    T         1.027   1.010   1.034   1.017   0.986   1.011   0.731   0.694   0.703
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    K         2.405   2.412   2.486   2.405   2.417   2.535   2.745   2.754   2.877
42    E        -0.975  -0.993  -0.961  -1.021  -1.048  -0.996  -0.779  -0.797  -0.748
43    A        -0.975  -0.997  -0.984  -0.602  -0.639  -0.608  -0.779  -0.800  -0.770
44    K         0.026   0.032   0.084  -0.487  -0.502  -0.399  -0.276  -0.268  -0.199
45    R        -0.285  -0.319  -0.362  -0.350  -0.428  -0.518  -0.276  -0.319  -0.366
46    T        -0.975  -0.965  -0.954  -0.844  -0.824  -0.815  -0.779  -0.769  -0.740
47    Y        -0.975  -0.965  -0.954  -0.677  -0.659  -0.643  -0.779  -0.769  -0.740
48    I         1.027   1.027   1.033   0.726   0.719   0.671   0.731   0.727   0.699
49    Q        -0.975  -0.976  -0.982  -0.827  -0.818  -0.840  -0.779  -0.779  -0.768
50    E        -0.975  -0.969  -0.966  -0.850  -0.834  -0.843  -0.779  -0.773  -0.752
51    Q         0.215   0.186   0.199   0.273   0.226   0.239  -0.024  -0.059  -0.043
52    C        -0.474  -0.488  -0.466  -0.049  -0.072  -0.022  -0.528  -0.540  -0.502
53    E        -1.475  -1.471  -1.431  -1.112  -1.111  -1.037  -1.031  -1.026  -0.969
54    F        -0.975  -0.982  -0.957  -0.685  -0.702  -0.653  -0.779  -0.785  -0.743
55    L        -0.285  -0.309  -0.373  -0.407  -0.440  -0.499  -0.276  -0.306  -0.380
56    E        -1.475  -1.471  -1.431  -1.451  -1.440  -1.381  -1.031  -1.026  -0.969
57    K        -0.975  -0.991  -0.958  -0.968  -0.997  -0.956  -0.779  -0.794  -0.744
58    L         1.322   1.317   1.245   1.099   1.083   1.000   1.295   1.284   1.125
59    R        -0.480  -0.503  -0.490  -0.427  -0.481  -0.461  -0.518  -0.544  -0.522
60    Q        -1.080  -1.077  -1.033  -0.751  -0.755  -0.670  -0.880  -0.875  -0.815
61    Q        -0.480  -0.463  -0.487  -0.738  -0.730  -0.763  -0.518  -0.497  -0.519
62    K        -0.480  -0.471  -0.470  -0.506  -0.494  -0.479  -0.518  -0.507  -0.498
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    R        -0.597  -0.588  -0.545  -0.691  -0.679  -0.609  -0.654  -0.643  -0.584
66    E        -0.597  -0.588  -0.545  -0.615  -0.602  -0.532  -0.654  -0.643  -0.584
67    G         0.154   0.109   0.145   0.066  -0.041   0.001  -0.087  -0.155  -0.109
68    R        -0.597  -0.588  -0.545  -0.458  -0.438  -0.372  -0.654  -0.643  -0.584
69    I         0.154   0.140   0.165  -0.280  -0.302  -0.258  -0.087  -0.110  -0.080
70    N        -0.975  -0.979  -0.956  -0.915  -0.915  -0.885  -0.779  -0.783  -0.742
71    I         0.527   0.554   0.408   0.790   0.838   0.599   0.479   0.521   0.292
72    L         0.527   0.552   0.400   0.344   0.376   0.171   0.479   0.517   0.280
73    S         0.026   0.032   0.084  -0.069  -0.054   0.020  -0.276  -0.268  -0.199
74    M         1.430   1.452   1.316   1.636   1.668   1.487   1.486   1.524   1.259
75    D         2.405   2.412   2.486   2.605   2.614   2.738   2.745   2.754   2.877
76    A         0.026   0.032   0.085  -0.272  -0.287  -0.198  -0.276  -0.268  -0.198
77    G         2.405   2.412   2.486   2.746   2.752   2.882   2.745   2.754   2.877
78    V         0.904   0.910   0.971   0.745   0.755   0.848   0.479   0.488   0.570
79    S         0.215   0.221   0.203  -0.052  -0.025  -0.057  -0.024  -0.008  -0.036
80    N         2.405   2.412   2.486   2.538   2.556   2.670   2.745   2.754   2.877
81    F         1.430   1.438   1.308   1.660   1.667   1.438   1.486   1.499   1.245
82    A         0.904   0.909   0.971   0.687   0.693   0.788   0.479   0.486   0.570
83    F         1.027   1.030   1.040   1.155   1.157   1.160   0.731   0.734   0.715
84    S         0.527   0.528   0.393   0.956   0.961   0.726   0.479   0.481   0.269
85    K        -0.285  -0.301  -0.357  -0.327  -0.342  -0.446  -0.276  -0.296  -0.360
86    M        -0.975  -0.991  -0.958  -1.107  -1.123  -1.060  -0.779  -0.794  -0.744
87    Q        -0.474  -0.475  -0.468  -0.521  -0.520  -0.508  -0.528  -0.526  -0.503
88    L        -0.474  -0.475  -0.468  -0.689  -0.666  -0.644  -0.528  -0.526  -0.503
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    L         0.154   0.159   0.178  -0.319  -0.317  -0.283  -0.087  -0.080  -0.060
98    N        -0.975  -0.955  -0.959  -0.884  -0.851  -0.857  -0.779  -0.758  -0.746
99    N        -0.975  -0.963  -0.958  -0.804  -0.775  -0.786  -0.779  -0.766  -0.744
100   D         0.527   0.521   0.402   0.739   0.734   0.543   0.479   0.471   0.282
101   P        -0.975  -0.963  -0.958  -0.801  -0.792  -0.776  -0.779  -0.766  -0.744
102   L        -0.474  -0.460  -0.456  -0.673  -0.652  -0.651  -0.528  -0.512  -0.492
103   P         1.430   1.382   1.313   1.845   1.775   1.678   1.486   1.401   1.253
104   K        -0.975  -0.952  -0.963  -1.059  -1.001  -1.053  -0.779  -0.755  -0.749
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   V         0.215   0.237   0.200  -0.091  -0.051  -0.129  -0.024   0.007  -0.043
108   L        -1.475  -1.471  -1.431  -1.444  -1.424  -1.374  -1.031  -1.026  -0.969
109   D        -1.475  -1.471  -1.431  -1.290  -1.287  -1.218  -1.031  -1.026  -0.969
110   W         1.430   1.414   1.308   1.948   1.925   1.784   1.486   1.458   1.243
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   Q        -0.975  -0.968  -0.963  -0.792  -0.782  -0.775  -0.779  -0.771  -0.749
118   K         2.405   2.412   2.486   2.405   2.417   2.535   2.745   2.754   2.877
119   I        -0.975  -0.979  -0.956  -1.021  -1.028  -0.999  -0.779  -0.783  -0.742
120   N        -0.474  -0.492  -0.458  -0.406  -0.421  -0.371  -0.528  -0.544  -0.494
121   L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
122   E        -0.474  -0.477  -0.470  -0.300  -0.307  -0.269  -0.528  -0.529  -0.506
123   E        -0.975  -0.979  -0.956  -0.833  -0.837  -0.806  -0.779  -0.783  -0.742
124   K         0.215   0.221   0.203   0.135   0.163   0.117  -0.024  -0.008  -0.036
125   F         0.215   0.186   0.199   0.418   0.379   0.417  -0.024  -0.059  -0.043
126   F        -0.474  -0.486  -0.472  -0.280  -0.298  -0.268  -0.528  -0.538  -0.508
127   Q        -1.475  -1.471  -1.431  -1.286  -1.276  -1.213  -1.031  -1.026  -0.969
128   -        -0.480  -0.469  -0.466  -0.584  -0.569  -0.579  -0.518  -0.504  -0.494
129   -        -0.480  -0.484  -0.457  -0.301  -0.310  -0.254  -0.518  -0.523  -0.482
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -0.597  -0.594  -0.545  -0.776  -0.767  -0.695  -0.654  -0.649  -0.584
135   N        -0.480  -0.486  -0.461  -0.322  -0.329  -0.286  -0.518  -0.525  -0.487
136   L        -1.080  -1.077  -1.033  -1.129  -1.127  -1.054  -0.880  -0.875  -0.815
137   K        -0.480  -0.489  -0.465  -0.557  -0.573  -0.547  -0.518  -0.528  -0.492
138   K         0.121   0.111   0.135  -0.239  -0.242  -0.212  -0.155  -0.166  -0.132
139   L         0.347   0.321   0.281   0.055   0.009  -0.039   0.207   0.167   0.097
140   S        -1.080  -1.077  -1.033  -1.131  -1.122  -1.056  -0.880  -0.875  -0.815
141   L         0.948   0.945   1.000   0.420   0.407   0.499   0.570   0.561   0.632
142   N        -0.285  -0.329  -0.366  -0.196  -0.255  -0.333  -0.276  -0.331  -0.372
143   P         1.027   1.037   1.048   1.062   1.080   1.063   0.731   0.748   0.731
144   A        -0.474  -0.486  -0.472  -0.404  -0.431  -0.398  -0.528  -0.538  -0.508
145   E        -0.975  -0.976  -0.982  -0.777  -0.780  -0.805  -0.779  -0.779  -0.768
146   T        -0.474  -0.442  -0.471  -0.587  -0.536  -0.552  -0.528  -0.494  -0.507
147   S         0.215   0.208   0.205   0.081   0.080   0.072  -0.024  -0.040  -0.037
148   E        -1.475  -1.471  -1.431  -1.096  -1.095  -1.020  -1.031  -1.026  -0.969
149   L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
150   V        -0.975  -0.991  -0.958  -0.734  -0.765  -0.709  -0.779  -0.794  -0.744
151   F        -0.975  -0.979  -0.956  -1.038  -1.060  -1.030  -0.779  -0.783  -0.742
152   N        -0.975  -0.969  -0.966  -0.998  -0.971  -0.992  -0.779  -0.773  -0.752
153   L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
154   T        -0.975  -0.976  -0.982  -0.772  -0.760  -0.787  -0.779  -0.779  -0.768
155   E         0.527   0.585   0.392   0.700   0.795   0.499   0.479   0.567   0.268
156   Y        -0.975  -0.997  -0.984  -0.606  -0.642  -0.617  -0.779  -0.800  -0.770
157   L         1.430   1.438   1.308   1.189   1.195   1.004   1.486   1.499   1.245
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   E        -0.597  -0.591  -0.545  -0.452  -0.442  -0.367  -0.654  -0.646  -0.584
161   S        -1.475  -1.471  -1.431  -1.512  -1.484  -1.443  -1.031  -1.026  -0.969
162   M        -0.975  -0.993  -0.961  -0.676  -0.723  -0.658  -0.779  -0.797  -0.748
163   P        -0.975  -0.938  -0.966  -0.648  -0.595  -0.628  -0.779  -0.740  -0.753
164   I        -1.475  -1.471  -1.431  -1.353  -1.348  -1.282  -1.031  -1.026  -0.969
165   P        -0.285  -0.258  -0.330   0.172   0.216   0.113  -0.276  -0.241  -0.326
166   D        -0.474  -0.459  -0.454  -0.292  -0.265  -0.256  -0.528  -0.511  -0.490
167   M        -0.285  -0.253  -0.367  -0.092  -0.028  -0.241  -0.276  -0.234  -0.373
168   F        -0.474  -0.459  -0.460  -0.341  -0.323  -0.308  -0.528  -0.511  -0.496
169   T        -1.475  -1.471  -1.431  -1.390  -1.407  -1.319  -1.031  -1.026  -0.969
170   I         0.215   0.210   0.197   0.271   0.264   0.260  -0.024  -0.035  -0.049
171   E         2.405   2.412   2.486   2.655   2.660   2.788   2.745   2.754   2.877
172   R         0.527   0.542   0.373   0.763   0.786   0.506   0.479   0.502   0.239
173   Q         2.405   2.412   2.486   2.668   2.679   2.802   2.745   2.754   2.877
174   R         2.405   2.412   2.486   2.661   2.667   2.795   2.745   2.754   2.877
175   T        -0.285  -0.301  -0.357  -0.085  -0.107  -0.201  -0.276  -0.296  -0.360
176   R         2.405   2.412   2.486   2.661   2.667   2.795   2.745   2.754   2.877
177   T         1.430   1.452   1.316   1.467   1.505   1.300   1.486   1.524   1.259
178   M        -0.474  -0.491  -0.464  -0.224  -0.247  -0.203  -0.528  -0.543  -0.499
179   S        -0.285  -0.309  -0.373  -0.241  -0.276  -0.367  -0.276  -0.306  -0.380
180   S        -0.285  -0.309  -0.373  -0.417  -0.445  -0.586  -0.276  -0.306  -0.380
181   R        -0.975  -0.952  -0.963  -1.148  -1.099  -1.158  -0.779  -0.755  -0.749
182   H        -0.480  -0.463  -0.487  -0.442  -0.417  -0.433  -0.518  -0.497  -0.519
183   I         0.215   0.254   0.209   0.167   0.228   0.170  -0.024   0.027  -0.027
184   L         1.430   1.382   1.313   1.241   1.170   1.088   1.486   1.401   1.253
185   D         0.215   0.234   0.209   0.334   0.358   0.332  -0.024   0.002  -0.028
186   P        -0.474  -0.488  -0.466  -0.284  -0.297  -0.262  -0.528  -0.540  -0.502
187   I         0.215   0.183   0.204   0.219   0.173   0.197  -0.024  -0.066  -0.039
188   L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
189   K         0.026   0.029   0.085  -0.487  -0.484  -0.387  -0.276  -0.272  -0.198
190   V         0.215   0.254   0.209   0.159   0.234   0.141  -0.024   0.027  -0.027
191   N         0.215   0.208   0.201   0.270   0.269   0.272  -0.024  -0.032  -0.039
192   I         0.215   0.186   0.199   0.203   0.170   0.198  -0.024  -0.059  -0.043
193   L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
194   E         2.405   2.412   2.486   2.655   2.660   2.788   2.745   2.754   2.877
195   Q        -0.474  -0.486  -0.472  -0.442  -0.459  -0.434  -0.528  -0.538  -0.508
196   I        -0.474  -0.471  -0.457  -0.619  -0.597  -0.583  -0.528  -0.523  -0.492
197   L         0.527   0.542   0.373   0.293   0.311   0.062   0.479   0.502   0.239
198   F         0.904   0.910   0.971   0.906   0.914   1.015   0.479   0.488   0.571
199   S         0.527   0.494   0.394   0.618   0.575   0.435   0.479   0.428   0.271
200   N         0.215   0.195   0.219   0.014  -0.015  -0.001  -0.024  -0.044  -0.019
201   L         0.215   0.186   0.199  -0.153  -0.188  -0.146  -0.024  -0.059  -0.043
202   E        -0.975  -0.952  -0.963  -0.545  -0.511  -0.516  -0.779  -0.755  -0.749
203   N        -0.285  -0.309  -0.373  -0.081  -0.107  -0.202  -0.276  -0.306  -0.380
204   K        -1.080  -1.074  -1.033  -1.262  -1.268  -1.189  -0.880  -0.873  -0.815
205   M        -0.480  -0.474  -0.467  -0.512  -0.503  -0.480  -0.518  -0.511  -0.494
206   K        -1.080  -1.074  -1.033  -1.027  -1.009  -0.950  -0.880  -0.873  -0.815
207   Y        -1.080  -1.074  -1.033  -0.994  -0.980  -0.917  -0.880  -0.873  -0.815
208   T        -0.597  -0.591  -0.545  -0.523  -0.521  -0.439  -0.654  -0.646  -0.584
209   N        -0.597  -0.591  -0.545  -0.574  -0.564  -0.491  -0.654  -0.646  -0.584
210   K        -0.597  -0.591  -0.545  -0.626  -0.621  -0.543  -0.654  -0.646  -0.584
211   I        -0.597  -0.591  -0.545  -0.842  -0.842  -0.762  -0.654  -0.646  -0.584
212   P         0.154   0.156   0.171   0.048   0.050   0.078  -0.087  -0.084  -0.071
213   N         0.154   0.150   0.177   0.088   0.081   0.113  -0.087  -0.094  -0.062
214   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   Y        -0.975  -0.997  -0.984  -0.612  -0.646  -0.624  -0.779  -0.800  -0.770
220   M        -0.975  -0.979  -0.956  -0.568  -0.579  -0.534  -0.779  -0.783  -0.742
221   V         0.215   0.232   0.206  -0.017  -0.017  -0.055  -0.024  -0.010  -0.035
222   C        -0.975  -0.993  -0.961  -0.830  -0.883  -0.803  -0.779  -0.797  -0.748
223   S         0.904   0.909   0.971   0.735   0.744   0.845   0.479   0.485   0.570
224   S         0.215   0.186   0.199   0.018  -0.035  -0.030  -0.024  -0.059  -0.043
225   D        -0.975  -0.997  -0.984  -1.119  -1.170  -1.174  -0.779  -0.800  -0.770
226   P         0.527   0.542   0.373   0.895   0.919   0.640   0.479   0.502   0.239
227   H        -0.975  -0.938  -0.966  -0.907  -0.858  -0.878  -0.779  -0.740  -0.753
228   R         0.215   0.186   0.199   0.076   0.028   0.033  -0.024  -0.059  -0.043
229   M         1.430   1.382   1.313   1.843   1.771   1.671   1.486   1.401   1.253
230   T        -0.474  -0.492  -0.458  -0.417  -0.431  -0.389  -0.528  -0.544  -0.494
231   S        -0.474  -0.478  -0.456  -0.543  -0.542  -0.499  -0.528  -0.529  -0.492
232   Y         0.904   0.909   0.971   0.906   0.908   1.013   0.479   0.485   0.570
233   W         1.430   1.414   1.308   1.912   1.890   1.732   1.486   1.458   1.243
234   C         0.904   0.909   0.972   0.611   0.625   0.733   0.479   0.486   0.572
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   I         1.322   1.363   1.253   1.454   1.519   1.347   1.295   1.367   1.139
249   P        -0.480  -0.489  -0.465  -0.348  -0.365  -0.319  -0.518  -0.528  -0.492
250   R         0.347   0.357   0.284   0.475   0.486   0.349   0.207   0.221   0.101
251   E        -1.080  -1.077  -1.033  -0.864  -0.861  -0.785  -0.880  -0.875  -0.815
252   E         0.154   0.151   0.167   0.066   0.068   0.067  -0.087  -0.093  -0.077
253   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   T         0.347   0.309   0.275   0.438   0.376   0.299   0.207   0.147   0.087
256   S         0.347   0.372   0.285   0.174   0.222   0.046   0.207   0.243   0.103
257   S        -1.080  -1.073  -1.033  -1.089  -1.073  -1.013  -0.880  -0.872  -0.815
258   K         0.121   0.155   0.153  -0.431  -0.396  -0.371  -0.155  -0.114  -0.109
259   K        -0.480  -0.445  -0.470  -0.528  -0.462  -0.521  -0.518  -0.475  -0.498
260   L         0.347   0.309   0.275   0.091   0.028  -0.006   0.207   0.147   0.087
261   K         0.347   0.399   0.301   0.220   0.304   0.138   0.207   0.284   0.128
262   S        -0.285  -0.285  -0.335  -0.373  -0.355  -0.466  -0.276  -0.276  -0.333
263   N         0.527   0.524   0.403   0.626   0.627   0.419   0.479   0.473   0.285
264   K        -0.975  -0.997  -0.984  -1.034  -1.052  -1.040  -0.779  -0.800  -0.770
265   H        -0.975  -0.993  -0.961  -1.018  -1.061  -1.005  -0.779  -0.797  -0.748
266   S        -0.285  -0.309  -0.373  -0.373  -0.408  -0.531  -0.276  -0.306  -0.380
267   K         2.405   2.412   2.486   2.405   2.417   2.535   2.745   2.754   2.877
268   D         0.527   0.554   0.408   0.579   0.621   0.408   0.479   0.521   0.292
269   S        -0.975  -0.955  -0.959  -1.107  -1.075  -1.086  -0.779  -0.758  -0.746
270   R         2.405   2.412   2.486   2.661   2.667   2.795   2.745   2.754   2.877
271   I         0.527   0.494   0.394   0.722   0.673   0.527   0.479   0.428   0.271
272   K        -0.474  -0.459  -0.460  -0.380  -0.355  -0.359  -0.528  -0.511  -0.496
273   L         1.430   1.382   1.313   1.243   1.172   1.091   1.486   1.401   1.253
274   V        -0.285  -0.287  -0.369   0.111   0.111   0.006  -0.276  -0.278  -0.375
275   K        -0.285  -0.263  -0.340  -0.311  -0.270  -0.398  -0.276  -0.247  -0.338
276   K        -1.475  -1.471  -1.431  -1.733  -1.716  -1.668  -1.031  -1.026  -0.969
277   I         0.026   0.032   0.085  -0.255  -0.269  -0.180  -0.276  -0.268  -0.198
278   L         1.027   1.001   1.032   0.537   0.485   0.529   0.731   0.676   0.697
279   S         0.154   0.218   0.177   0.287   0.406   0.316  -0.087   0.011  -0.062
280   T        -0.597  -0.587  -0.545  -0.586  -0.559  -0.503  -0.654  -0.642  -0.584
281   S         0.154   0.109   0.145  -0.032  -0.101  -0.046  -0.087  -0.156  -0.109
282   I         0.154   0.149   0.167   0.087   0.079   0.096  -0.087  -0.097  -0.077
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   L        -0.597  -0.587  -0.545  -0.854  -0.848  -0.775  -0.654  -0.642  -0.584
286   E         0.026   0.029   0.085  -0.124  -0.116  -0.029  -0.276  -0.272  -0.198
287   G        -0.975  -0.955  -0.959  -0.734  -0.701  -0.714  -0.779  -0.758  -0.746
288   N        -0.975  -0.938  -0.966  -0.807  -0.747  -0.798  -0.779  -0.740  -0.753
289   S        -0.285  -0.275  -0.352  -0.146  -0.136  -0.285  -0.276  -0.263  -0.354
290   T        -0.474  -0.462  -0.462  -0.403  -0.387  -0.375  -0.528  -0.514  -0.498
291   S        -1.080  -1.074  -1.033  -1.242  -1.246  -1.169  -0.880  -0.873  -0.815
292   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   V         0.948   0.981   1.016   0.925   0.988   1.034   0.570   0.635   0.664
297   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   R         0.154   0.109   0.145   0.125   0.038   0.089  -0.087  -0.156  -0.109
306   I         0.948   0.969   1.011   0.393   0.420   0.486   0.570   0.611   0.655
307   R        -0.480  -0.463  -0.487  -0.217  -0.194  -0.236  -0.518  -0.497  -0.519
308   N        -0.480  -0.489  -0.465  -0.549  -0.558  -0.519  -0.518  -0.528  -0.492
309   A         0.121   0.118   0.149   0.250   0.249   0.303  -0.155  -0.158  -0.113
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   L        -0.474  -0.460  -0.460  -0.492  -0.472  -0.479  -0.528  -0.511  -0.496
312   T         0.215   0.226   0.212   0.219   0.240   0.223  -0.024  -0.012  -0.028
313   K         0.026   0.031   0.087  -0.205  -0.191  -0.102  -0.276  -0.269  -0.196
314   K         0.347   0.331   0.268   0.148   0.114  -0.018   0.207   0.183   0.077
315   K         0.121   0.134   0.155  -0.169  -0.141  -0.124  -0.155  -0.138  -0.108
316   S         1.322   1.317   1.245   1.269   1.270   1.126   1.295   1.284   1.125
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   F        -0.285  -0.319  -0.362  -0.469  -0.524  -0.561  -0.276  -0.319  -0.366
319   K        -0.975  -0.997  -0.984  -0.875  -0.896  -0.863  -0.779  -0.800  -0.770
320   L         0.527   0.516   0.385   0.262   0.240   0.038   0.479   0.463   0.257
321   C        -0.285  -0.261  -0.358  -0.088  -0.048  -0.238  -0.276  -0.245  -0.361
322   D        -0.285  -0.253  -0.367  -0.281  -0.229  -0.405  -0.276  -0.234  -0.373
323   I        -0.474  -0.473  -0.471  -0.451  -0.434  -0.453  -0.528  -0.526  -0.507
324   L        -0.285  -0.301  -0.357  -0.653  -0.681  -0.779  -0.276  -0.296  -0.360
325   E         0.121   0.100   0.149  -0.128  -0.166  -0.093  -0.155  -0.179  -0.113
326   I        -0.474  -0.442  -0.471  -0.705  -0.646  -0.682  -0.528  -0.494  -0.507
327   Q         0.215   0.234   0.209   0.051   0.083   0.054  -0.024   0.002  -0.028
328   D        -0.975  -0.997  -0.984  -0.820  -0.851  -0.834  -0.779  -0.800  -0.770
329   -        -0.597  -0.594  -0.545  -0.746  -0.750  -0.665  -0.654  -0.649  -0.584
330   N        -0.480  -0.515  -0.490  -0.406  -0.457  -0.418  -0.518  -0.560  -0.522
331   S         0.347   0.338   0.301  -0.008  -0.024  -0.090   0.207   0.192   0.128
332   G         0.154   0.109   0.145   0.310   0.224   0.285  -0.087  -0.156  -0.109
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   V        -1.080  -1.077  -1.033  -1.076  -1.060  -1.000  -0.880  -0.875  -0.815
337   R        -0.480  -0.453  -0.461  -0.533  -0.480  -0.507  -0.518  -0.485  -0.487
338   K         2.405   2.412   2.486   2.405   2.417   2.535   2.745   2.754   2.877
339   D        -0.474  -0.501  -0.482  -0.583  -0.626  -0.605  -0.528  -0.554  -0.518
340   D         2.405   2.412   2.486   2.605   2.614   2.738   2.745   2.754   2.877
341   D         2.405   2.412   2.486   2.605   2.614   2.738   2.745   2.754   2.877
342   L         1.430   1.382   1.313   1.243   1.172   1.091   1.486   1.401   1.253
343   A         0.215   0.208   0.201   0.333   0.329   0.333  -0.024  -0.032  -0.039
344   D         2.405   2.412   2.486   2.605   2.614   2.738   2.745   2.754   2.877
345   S         2.405   2.412   2.486   2.415   2.430   2.545   2.745   2.754   2.877
346   F         0.215   0.199   0.213  -0.100  -0.128  -0.085  -0.024  -0.037  -0.021
347   L         2.405   2.412   2.486   2.151   2.154   2.277   2.745   2.754   2.877
348   H         0.215   0.186   0.199   0.451   0.405   0.424  -0.024  -0.059  -0.043
349   C        -0.474  -0.460  -0.456  -0.213  -0.193  -0.173  -0.528  -0.512  -0.492
350   L         0.527   0.468   0.374   0.265   0.167   0.024   0.479   0.390   0.240
351   S        -0.975  -0.976  -0.982  -0.747  -0.743  -0.749  -0.779  -0.779  -0.768
352   W         0.527   0.542   0.373   0.977   1.001   0.721   0.479   0.502   0.239
353   M        -0.975  -0.955  -0.959  -0.859  -0.824  -0.853  -0.779  -0.758  -0.746
354   E         0.215   0.249   0.200   0.213   0.263   0.177  -0.024   0.019  -0.044
355   W         0.527   0.542   0.373   0.960   0.984   0.698   0.479   0.502   0.239
356   L         1.322   1.317   1.245   1.058   1.041   0.945   1.295   1.284   1.125
357   K        -0.480  -0.463  -0.487  -0.439  -0.400  -0.470  -0.518  -0.497  -0.519
358   N         1.322   1.317   1.245   1.474   1.476   1.372   1.295   1.284   1.125
359   Y         0.347   0.331   0.268   0.476   0.443   0.299   0.207   0.183   0.077
360   E        -0.480  -0.503  -0.490  -0.310  -0.345  -0.327  -0.518  -0.544  -0.522
361   S         0.121   0.119   0.153  -0.074  -0.068  -0.021  -0.155  -0.156  -0.109
362   I         0.347   0.358   0.301   0.024   0.032  -0.047   0.207   0.223   0.128
363   T        -0.480  -0.453  -0.461  -0.691  -0.663  -0.644  -0.518  -0.485  -0.487
364   E        -0.480  -0.477  -0.459  -0.379  -0.384  -0.349  -0.518  -0.514  -0.485
365   L        -0.480  -0.480  -0.460  -0.726  -0.733  -0.679  -0.518  -0.518  -0.486
366   L        -0.480  -0.477  -0.459  -0.733  -0.731  -0.686  -0.518  -0.514  -0.485
367   N         0.121   0.119   0.153  -0.008  -0.003   0.047  -0.155  -0.156  -0.109
368   S        -0.480  -0.480  -0.460  -0.584  -0.573  -0.551  -0.518  -0.518  -0.486
369   K         0.121   0.111   0.135  -0.073  -0.072  -0.026  -0.155  -0.166  -0.132
370   T        -1.080  -1.077  -1.033  -0.980  -0.969  -0.903  -0.880  -0.875  -0.815
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   L         0.347   0.343   0.279   0.447   0.440   0.299   0.207   0.201   0.094
377   V        -0.480  -0.480  -0.460  -0.439  -0.429  -0.415  -0.518  -0.518  -0.486
378   K        -0.975  -0.938  -0.966  -0.749  -0.687  -0.735  -0.779  -0.740  -0.753
379   T        -0.285  -0.275  -0.352  -0.048  -0.032  -0.147  -0.276  -0.263  -0.354
380   Q        -0.285  -0.242  -0.356  -0.083  -0.012  -0.210  -0.276  -0.220  -0.359
381   F        -0.975  -0.969  -0.966  -0.960  -0.969  -0.968  -0.779  -0.773  -0.752
382   G         0.215   0.221   0.203   0.125   0.136   0.121  -0.024  -0.008  -0.036
383   Q        -0.597  -0.593  -0.545  -0.408  -0.401  -0.322  -0.654  -0.648  -0.584
384   V         0.121   0.094   0.135   0.290   0.253   0.324  -0.155  -0.187  -0.132
385   F         0.121   0.094   0.155  -0.180  -0.211  -0.118  -0.155  -0.187  -0.107
386   E        -0.474  -0.491  -0.464  -0.379  -0.406  -0.357  -0.528  -0.543  -0.499
387   F         1.027   1.016   1.036   0.613   0.586   0.626   0.731   0.706   0.707
388   C         1.027   1.016   1.036   1.059   1.042   1.076   0.731   0.706   0.707
389   E         0.215   0.234   0.209   0.075   0.104   0.078  -0.024   0.002  -0.028
390   N        -0.975  -0.997  -0.984  -0.868  -0.894  -0.877  -0.779  -0.800  -0.770
391   K        -0.474  -0.460  -0.460  -0.472  -0.443  -0.450  -0.528  -0.511  -0.496
392   V         0.121   0.107   0.143  -0.101  -0.129  -0.087  -0.155  -0.171  -0.121
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
400   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
401   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
402   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
403   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
404   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
406   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
407   Q         0.121   0.111   0.135  -0.115  -0.135  -0.104  -0.155  -0.166  -0.132
408   K        -0.480  -0.477  -0.459  -0.442  -0.432  -0.397  -0.518  -0.514  -0.485
409   L        -1.080  -1.077  -1.033  -1.162  -1.160  -1.087  -0.880  -0.875  -0.815
410   K         0.948   0.969   1.011   0.559   0.612   0.653   0.570   0.611   0.655
411   F         0.121   0.117   0.151   0.113   0.110   0.168  -0.155  -0.160  -0.112
412   L        -0.480  -0.503  -0.490  -0.832  -0.868  -0.825  -0.518  -0.544  -0.522
413   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
414   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
415   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
416   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
417   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
418   N         0.154   0.165   0.175  -0.198  -0.176  -0.181  -0.087  -0.070  -0.066
419   D        -0.597  -0.594  -0.545  -0.857  -0.857  -0.778  -0.654  -0.650  -0.584
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03702
Output conservation file - output/Q03702
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
