1     M         1.943   1.979   2.030   2.203   2.266   2.346   2.153   2.207   2.287
2     I        -1.002  -1.058  -1.024  -0.877  -0.975  -0.911  -0.863  -0.914  -0.858
3     L         0.700   0.748   0.649   0.712   0.789   0.611   0.582   0.659   0.472
4     R        -1.122  -1.110  -1.066  -1.201  -1.171  -1.112  -0.988  -0.966  -0.901
5     E        -1.122  -1.110  -1.066  -1.144  -1.111  -1.055  -0.988  -0.966  -0.901
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    I        -1.122  -1.114  -1.066  -1.171  -1.168  -1.082  -0.988  -0.970  -0.901
22    H        -0.355  -0.337  -0.351  -0.260  -0.246  -0.254  -0.465  -0.435  -0.450
23    K         0.700   0.682   0.630   0.904   0.878   0.770   0.582   0.546   0.438
24    R         0.700   0.682   0.630   0.597   0.568   0.470   0.582   0.546   0.438
25    Q        -0.355  -0.289  -0.342  -0.419  -0.309  -0.401  -0.465  -0.368  -0.438
26    D        -1.122  -1.114  -1.066  -1.039  -1.009  -0.948  -0.988  -0.970  -0.901
27    D        -0.355  -0.347  -0.355  -0.403  -0.385  -0.405  -0.465  -0.448  -0.456
28    N         0.411   0.430   0.482   0.146   0.178   0.256   0.059   0.086   0.162
29    N         1.943   1.979   2.030   1.926   1.985   2.065   2.153   2.207   2.287
30    N         0.536   0.512   0.530   0.546   0.520   0.556   0.291   0.239   0.254
31    N         0.536   0.512   0.530   0.502   0.471   0.502   0.291   0.239   0.254
32    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    E        -0.355  -0.300  -0.345  -0.411  -0.313  -0.396  -0.465  -0.386  -0.441
34    A        -1.122  -1.102  -1.066  -1.117  -1.088  -1.027  -0.988  -0.958  -0.901
35    I        -0.486  -0.459  -0.424  -0.489  -0.448  -0.389  -0.639  -0.599  -0.547
36    T         0.536   0.483   0.530   0.383   0.285   0.360   0.291   0.185   0.254
37    D         0.536   0.483   0.530   0.409   0.324   0.383   0.291   0.185   0.254
38    D         0.536   0.483   0.530   0.393   0.294   0.364   0.291   0.185   0.254
39    D         0.536   0.483   0.530   0.372   0.270   0.337   0.291   0.185   0.254
40    P         0.536   0.483   0.530   0.435   0.341   0.429   0.291   0.185   0.254
41    F        -0.486  -0.459  -0.424  -0.558  -0.525  -0.459  -0.639  -0.599  -0.547
42    S        -0.355  -0.321  -0.348  -0.298  -0.240  -0.265  -0.465  -0.414  -0.446
43    S        -0.355  -0.369  -0.355  -0.558  -0.590  -0.573  -0.465  -0.482  -0.456
44    S         0.411   0.433   0.482   0.180   0.220   0.294   0.059   0.091   0.162
45    S         0.837   0.871   0.701   0.906   0.960   0.737   0.813   0.867   0.564
46    W         0.837   0.716   0.720   1.159   0.986   0.987   0.813   0.605   0.599
47    R        -1.615  -1.594  -1.564  -1.525  -1.474  -1.442  -1.198  -1.168  -1.114
48    W        -0.158  -0.264  -0.269   0.177   0.004  -0.005  -0.193  -0.336  -0.338
49    G         0.455   0.442   0.494   0.300   0.263   0.343   0.143   0.108   0.184
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    R         0.837   0.716   0.720   0.848   0.682   0.681   0.813   0.605   0.599
54    W         0.837   0.716   0.720   1.158   0.981   0.985   0.813   0.605   0.599
55    I        -0.389  -0.370  -0.369  -0.434  -0.403  -0.397  -0.528  -0.493  -0.480
56    F        -0.389  -0.335  -0.363  -0.346  -0.277  -0.297  -0.528  -0.457  -0.475
57    F         1.943   1.979   2.030   2.082   2.145   2.223   2.153   2.207   2.287
58    I        -0.355  -0.334  -0.346  -0.361  -0.332  -0.351  -0.465  -0.432  -0.443
59    F        -0.158  -0.066  -0.253   0.009   0.133  -0.130  -0.193  -0.063  -0.316
60    F         1.943   1.979   2.030   2.082   2.145   2.223   2.153   2.207   2.287
61    I        -0.158  -0.082  -0.246   0.047   0.152  -0.069  -0.193  -0.083  -0.306
62    V         0.837   0.871   0.701   0.972   1.027   0.781   0.813   0.867   0.564
63    A        -1.002  -0.906  -0.993  -0.874  -0.727  -0.857  -0.863  -0.747  -0.825
64    L        -0.389  -0.441  -0.367  -0.407  -0.488  -0.363  -0.528  -0.579  -0.480
65    L         0.837   0.716   0.720   0.957   0.775   0.787   0.813   0.605   0.599
66    I        -1.002  -1.023  -1.003  -0.842  -0.870  -0.838  -0.863  -0.879  -0.836
67    L        -1.615  -1.594  -1.564  -1.237  -1.218  -1.149  -1.198  -1.168  -1.114
68    L        -1.002  -0.973  -0.992  -0.964  -0.931  -0.955  -0.863  -0.827  -0.825
69    F        -0.158  -0.046  -0.242   0.011   0.172  -0.110  -0.193  -0.035  -0.301
70    S        -1.002  -0.939  -0.995  -0.955  -0.847  -0.951  -0.863  -0.784  -0.827
71    T         0.837   0.716   0.720   0.772   0.585   0.591   0.813   0.605   0.599
72    A        -1.002  -0.973  -0.992  -0.826  -0.788  -0.804  -0.863  -0.827  -0.825
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    K         0.455   0.459   0.508   0.337   0.351   0.424   0.143   0.141   0.211
76    V        -0.389  -0.442  -0.364  -0.350  -0.413  -0.291  -0.528  -0.580  -0.476
77    N         0.837   0.716   0.720   0.852   0.669   0.669   0.813   0.605   0.599
78    R        -0.389  -0.356  -0.364  -0.350  -0.264  -0.282  -0.528  -0.476  -0.474
79    R        -0.158  -0.147  -0.276  -0.067  -0.041  -0.225  -0.193  -0.172  -0.348
80    R         1.943   1.979   2.030   1.886   1.951   2.024   2.153   2.207   2.287
81    R        -1.002  -1.034  -1.005  -1.088  -1.132  -1.101  -0.863  -0.890  -0.838
82    I        -1.002  -0.892  -0.984  -0.912  -0.737  -0.886  -0.863  -0.730  -0.816
83    M        -1.615  -1.594  -1.564  -1.299  -1.257  -1.212  -1.198  -1.168  -1.114
84    G         0.837   0.716   0.720   0.944   0.758   0.765   0.813   0.605   0.599
85    Q        -1.002  -1.034  -1.005  -0.947  -1.028  -0.962  -0.863  -0.890  -0.838
86    A        -0.389  -0.437  -0.369  -0.502  -0.581  -0.466  -0.528  -0.573  -0.480
87    P         1.943   1.979   2.030   1.832   1.879   1.970   2.153   2.207   2.287
88    I        -0.158  -0.246  -0.267  -0.038  -0.192  -0.214  -0.193  -0.314  -0.335
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   R        -0.389  -0.441  -0.367  -0.450  -0.516  -0.405  -0.528  -0.579  -0.480
105   G         0.837   0.871   0.701   0.973   1.024   0.776   0.813   0.867   0.564
106   T         0.455   0.442   0.494   0.196   0.167   0.252   0.143   0.108   0.184
107   A        -0.158  -0.147  -0.276  -0.154  -0.123  -0.360  -0.193  -0.172  -0.348
108   W         0.837   0.716   0.720   1.132   0.953   0.946   0.813   0.605   0.599
109   L        -0.389  -0.441  -0.367  -0.262  -0.336  -0.217  -0.528  -0.579  -0.480
110   T         0.837   0.716   0.720   0.804   0.623   0.638   0.813   0.605   0.599
111   P         1.943   1.979   2.030   1.851   1.903   1.988   2.153   2.207   2.287
112   P         1.943   1.979   2.030   1.851   1.903   1.988   2.153   2.207   2.287
113   T         0.411   0.430   0.482   0.040   0.062   0.149   0.059   0.086   0.162
114   Y         1.943   1.979   2.030   2.045   2.101   2.186   2.153   2.207   2.287
115   R        -0.158  -0.264  -0.269  -0.119  -0.275  -0.284  -0.193  -0.336  -0.338
116   Q         1.943   1.979   2.030   2.011   2.056   2.151   2.153   2.207   2.287
117   S         0.837   0.716   0.720   0.850   0.672   0.683   0.813   0.605   0.599
118   E         0.455   0.438   0.490   0.326   0.291   0.372   0.143   0.102   0.178
119   R        -1.002  -1.058  -1.024  -1.031  -1.109  -1.067  -0.863  -0.914  -0.858
120   D        -1.002  -1.058  -1.024  -0.920  -1.010  -0.950  -0.863  -0.914  -0.858
121   Y        -0.158  -0.246  -0.267  -0.048  -0.201  -0.242  -0.193  -0.314  -0.335
122   N         0.837   0.716   0.720   0.881   0.707   0.713   0.813   0.605   0.599
123   G        -1.615  -1.594  -1.564  -1.306  -1.292  -1.219  -1.198  -1.168  -1.114
124   T        -0.158  -0.147  -0.276  -0.255  -0.243  -0.463  -0.193  -0.172  -0.348
125   Q        -1.002  -1.058  -1.024  -0.955  -1.073  -1.007  -0.863  -0.914  -0.858
126   R        -1.615  -1.594  -1.564  -1.622  -1.585  -1.540  -1.198  -1.168  -1.114
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   C        -1.002  -0.906  -0.993  -0.759  -0.650  -0.711  -0.863  -0.747  -0.825
132   V        -1.002  -1.058  -1.024  -0.928  -1.020  -0.970  -0.863  -0.914  -0.858
133   E        -1.002  -1.058  -1.024  -0.861  -0.908  -0.888  -0.863  -0.914  -0.858
134   D        -0.158  -0.102  -0.262  -0.096   0.004  -0.263  -0.193  -0.111  -0.328
135   Y         1.943   1.979   2.030   2.037   2.091   2.178   2.153   2.207   2.287
136   V         1.943   1.979   2.030   1.991   2.048   2.131   2.153   2.207   2.287
137   P         1.943   1.979   2.030   1.832   1.879   1.970   2.153   2.207   2.287
138   E        -1.002  -0.906  -0.993  -1.091  -0.939  -1.076  -0.863  -0.747  -0.825
139   Y         1.943   1.979   2.030   2.037   2.091   2.178   2.153   2.207   2.287
140   T         0.837   0.847   0.690   0.772   0.789   0.540   0.813   0.827   0.545
141   E        -0.158  -0.264  -0.269  -0.052  -0.208  -0.229  -0.193  -0.336  -0.338
142   T         0.455   0.474   0.491   0.188   0.220   0.240   0.143   0.169   0.180
143   A        -0.158  -0.204  -0.242  -0.186  -0.271  -0.341  -0.193  -0.259  -0.301
144   N         0.837   0.847   0.690   0.840   0.862   0.600   0.813   0.827   0.545
145   E        -0.158  -0.204  -0.242  -0.073  -0.136  -0.211  -0.193  -0.259  -0.301
146   N         0.837   0.847   0.690   0.889   0.912   0.677   0.813   0.827   0.545
147   D         1.943   1.979   2.030   1.945   2.010   2.085   2.153   2.207   2.287
148   L         0.837   0.847   0.690   1.008   1.031   0.818   0.813   0.827   0.545
149   G         1.943   1.979   2.030   2.004   2.058   2.145   2.153   2.207   2.287
150   F        -0.158  -0.171  -0.231   0.013  -0.028  -0.101  -0.193  -0.217  -0.286
151   Y         0.837   0.716   0.720   1.016   0.844   0.855   0.813   0.605   0.599
152   D         1.943   1.979   2.030   1.945   2.010   2.085   2.153   2.207   2.287
153   E        -1.615  -1.594  -1.564  -1.433  -1.356  -1.348  -1.198  -1.168  -1.114
154   R        -1.615  -1.594  -1.564  -1.554  -1.500  -1.471  -1.198  -1.168  -1.114
155   G         1.943   1.979   2.030   2.004   2.058   2.145   2.153   2.207   2.287
156   E        -1.615  -1.594  -1.564  -1.344  -1.317  -1.258  -1.198  -1.168  -1.114
157   F         1.943   1.979   2.030   2.082   2.145   2.223   2.153   2.207   2.287
158   H         1.943   1.979   2.030   2.228   2.288   2.372   2.153   2.207   2.287
159   P        -1.615  -1.594  -1.564  -1.413  -1.375  -1.328  -1.198  -1.168  -1.114
160   N         0.837   0.716   0.720   0.852   0.669   0.669   0.813   0.605   0.599
161   G        -1.615  -1.594  -1.564  -1.597  -1.569  -1.514  -1.198  -1.168  -1.114
162   K        -0.158  -0.264  -0.269   0.083  -0.100  -0.117  -0.193  -0.336  -0.338
163   T        -0.158  -0.171  -0.231  -0.186  -0.219  -0.321  -0.193  -0.217  -0.286
164   E        -0.158  -0.147  -0.276   0.003   0.038  -0.167  -0.193  -0.172  -0.348
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   Y        -0.486  -0.459  -0.424  -0.449  -0.435  -0.348  -0.639  -0.599  -0.547
170   L         1.943   1.979   2.030   1.941   1.994   2.080   2.153   2.207   2.287
171   A        -0.355  -0.244  -0.342  -0.471  -0.301  -0.451  -0.465  -0.306  -0.438
172   P         1.943   1.979   2.030   1.860   1.909   1.998   2.153   2.207   2.287
173   P         1.943   1.979   2.030   1.860   1.909   1.998   2.153   2.207   2.287
174   P         0.700   0.780   0.635   0.602   0.722   0.489   0.582   0.715   0.446
175   L        -0.355  -0.414  -0.376  -0.366  -0.470  -0.404  -0.465  -0.540  -0.484
176   S         0.411   0.430   0.482   0.118   0.148   0.229   0.059   0.086   0.162
177   E        -1.122  -1.114  -1.066  -1.088  -1.073  -0.997  -0.988  -0.970  -0.901
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   E         0.700   0.686   0.629   0.656   0.631   0.516   0.582   0.553   0.435
182   Q        -0.355  -0.349  -0.353  -0.196  -0.177  -0.183  -0.465  -0.452  -0.453
183   A         0.700   0.682   0.630   0.607   0.574   0.477   0.582   0.546   0.438
184   S        -1.122  -1.114  -1.066  -1.227  -1.205  -1.139  -0.988  -0.970  -0.901
185   S        -1.122  -1.114  -1.066  -1.320  -1.311  -1.234  -0.988  -0.970  -0.901
186   T        -0.355  -0.349  -0.353  -0.569  -0.565  -0.573  -0.465  -0.452  -0.453
187   D         0.700   0.754   0.652   0.688   0.776   0.610   0.582   0.671   0.477
188   -        -0.486  -0.476  -0.424  -0.809  -0.796  -0.714  -0.639  -0.620  -0.547
189   -        -0.486  -0.476  -0.424  -0.829  -0.815  -0.735  -0.639  -0.620  -0.547
190   -        -0.486  -0.476  -0.424  -0.516  -0.492  -0.416  -0.639  -0.620  -0.547
191   -        -0.486  -0.476  -0.424  -0.623  -0.606  -0.525  -0.639  -0.620  -0.547
192   -        -0.486  -0.476  -0.424  -0.497  -0.481  -0.397  -0.639  -0.620  -0.547
193   K        -1.122  -1.114  -1.066  -1.015  -1.003  -0.923  -0.988  -0.970  -0.901
194   D        -1.122  -1.114  -1.066  -1.150  -1.135  -1.061  -0.988  -0.970  -0.901
195   L        -0.355  -0.390  -0.376  -0.130  -0.164  -0.133  -0.465  -0.507  -0.484
196   Q        -0.355  -0.347  -0.355  -0.267  -0.244  -0.267  -0.465  -0.448  -0.456
197   R         0.700   0.754   0.652   0.647   0.732   0.572   0.582   0.671   0.477
198   P        -0.355  -0.390  -0.376  -0.525  -0.588  -0.566  -0.465  -0.507  -0.484
199   V        -0.355  -0.289  -0.342  -0.501  -0.401  -0.479  -0.465  -0.368  -0.438
200   A         0.411   0.430   0.482   0.090   0.115   0.200   0.059   0.086   0.162
201   A        -0.355  -0.390  -0.376  -0.495  -0.560  -0.540  -0.465  -0.507  -0.484
202   V        -0.355  -0.289  -0.342  -0.403  -0.302  -0.378  -0.465  -0.368  -0.438
203   V        -1.122  -1.114  -1.066  -1.063  -1.050  -0.972  -0.988  -0.970  -0.901
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   R         0.700   0.682   0.630   0.647   0.622   0.537   0.582   0.546   0.438
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   I        -0.355  -0.349  -0.353  -0.288  -0.276  -0.288  -0.465  -0.452  -0.453
214   P         1.943   1.979   2.030   1.851   1.903   1.988   2.153   2.207   2.287
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   S        -0.355  -0.349  -0.353  -0.452  -0.448  -0.450  -0.465  -0.452  -0.453
221   E        -0.355  -0.390  -0.376  -0.374  -0.427  -0.411  -0.465  -0.507  -0.484
222   S        -0.486  -0.475  -0.424  -0.733  -0.711  -0.637  -0.639  -0.619  -0.547
223   E        -0.355  -0.334  -0.346  -0.439  -0.401  -0.429  -0.465  -0.432  -0.443
224   F        -1.122  -1.114  -1.066  -0.991  -0.977  -0.899  -0.988  -0.970  -0.901
225   D         1.943   1.979   2.030   1.940   2.002   2.079   2.153   2.207   2.287
226   F        -0.486  -0.470  -0.424  -0.523  -0.498  -0.424  -0.639  -0.613  -0.547
227   N        -0.486  -0.470  -0.424  -0.665  -0.632  -0.568  -0.639  -0.613  -0.547
228   L        -0.355  -0.366  -0.353  -0.291  -0.312  -0.284  -0.465  -0.478  -0.453
229   L        -0.355  -0.315  -0.348  -0.354  -0.281  -0.347  -0.465  -0.406  -0.446
230   R         0.700   0.612   0.630   0.642   0.505   0.516   0.582   0.422   0.438
231   P         1.943   1.979   2.030   1.832   1.879   1.970   2.153   2.207   2.287
232   T        -1.002  -0.964  -0.998  -1.088  -1.025  -1.082  -0.863  -0.810  -0.831
233   M        -1.122  -1.114  -1.066  -1.039  -1.044  -0.948  -0.988  -0.970  -0.901
234   N        -1.122  -1.114  -1.066  -1.188  -1.165  -1.099  -0.988  -0.970  -0.901
235   N        -0.355  -0.390  -0.376  -0.531  -0.603  -0.594  -0.465  -0.507  -0.484
236   F        -0.355  -0.390  -0.376  -0.320  -0.382  -0.377  -0.465  -0.507  -0.484
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   V        -1.122  -1.114  -1.066  -1.108  -1.085  -1.018  -0.988  -0.970  -0.901
241   N         0.700   0.774   0.661   0.625   0.739   0.555   0.582   0.705   0.494
242   G         0.700   0.682   0.630   0.729   0.700   0.598   0.582   0.546   0.438
243   Q        -0.355  -0.289  -0.342  -0.481  -0.373  -0.464  -0.465  -0.368  -0.438
244   S         0.700   0.682   0.630   0.661   0.634   0.551   0.582   0.546   0.438
245   N        -0.355  -0.347  -0.355  -0.455  -0.437  -0.465  -0.465  -0.448  -0.456
246   R        -1.122  -1.114  -1.066  -1.352  -1.347  -1.266  -0.988  -0.970  -0.901
247   N        -1.122  -1.114  -1.066  -1.184  -1.173  -1.095  -0.988  -0.970  -0.901
248   E        -0.355  -0.390  -0.376  -0.406  -0.462  -0.450  -0.465  -0.507  -0.484
249   Q        -0.355  -0.337  -0.351  -0.511  -0.495  -0.505  -0.465  -0.435  -0.450
250   H        -1.122  -1.114  -1.066  -0.924  -0.914  -0.831  -0.988  -0.970  -0.901
251   S        -1.122  -1.114  -1.066  -1.171  -1.153  -1.082  -0.988  -0.970  -0.901
252   P        -1.122  -1.114  -1.066  -1.289  -1.275  -1.202  -0.988  -0.970  -0.901
253   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   E        -0.355  -0.390  -0.376  -0.448  -0.508  -0.501  -0.465  -0.507  -0.484
256   S        -0.355  -0.347  -0.355  -0.518  -0.509  -0.531  -0.465  -0.448  -0.456
257   S         0.700   0.686   0.629   0.600   0.573   0.465   0.582   0.553   0.435
258   S         0.700   0.686   0.629   0.590   0.562   0.451   0.582   0.553   0.435
259   F        -0.355  -0.334  -0.346  -0.279  -0.244  -0.259  -0.465  -0.432  -0.443
260   D        -0.355  -0.334  -0.346  -0.518  -0.487  -0.513  -0.465  -0.432  -0.443
261   V        -0.355  -0.390  -0.376  -0.403  -0.468  -0.455  -0.465  -0.507  -0.484
262   N        -0.355  -0.337  -0.351  -0.317  -0.280  -0.317  -0.465  -0.435  -0.450
263   N        -1.122  -1.114  -1.066  -0.898  -0.874  -0.804  -0.988  -0.970  -0.901
264   A        -0.355  -0.289  -0.342  -0.485  -0.382  -0.464  -0.465  -0.368  -0.438
265   P        -1.122  -1.114  -1.066  -1.214  -1.206  -1.126  -0.988  -0.970  -0.901
266   A        -0.355  -0.347  -0.355  -0.455  -0.445  -0.458  -0.465  -0.448  -0.456
267   R        -0.355  -0.390  -0.376  -0.518  -0.578  -0.564  -0.465  -0.507  -0.484
268   A        -0.355  -0.347  -0.355  -0.555  -0.546  -0.574  -0.465  -0.448  -0.456
269   K        -0.355  -0.289  -0.342  -0.383  -0.284  -0.356  -0.465  -0.368  -0.438
270   V        -0.355  -0.289  -0.342  -0.531  -0.431  -0.513  -0.465  -0.368  -0.438
271   S        -1.122  -1.114  -1.066  -1.019  -1.001  -0.927  -0.988  -0.970  -0.901
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   K        -1.002  -1.058  -1.024  -0.787  -0.894  -0.844  -0.863  -0.914  -0.858
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03446
Output conservation file - output/Q03446
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
