1     M         1.961   2.079   2.157   2.185   2.391   2.487   2.181   2.368   2.506
2     A         1.123   1.080   0.949   1.267   1.174   1.031   1.165   1.079   0.813
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    R         0.334   0.212   0.133   0.465   0.290   0.143   0.318   0.125   0.015
17    Q         1.123   0.952   0.995   1.210   0.983   1.037   1.165   0.850   0.900
18    N         0.334   0.065   0.096   0.607   0.224   0.221   0.318  -0.077  -0.043
19    F         1.123   0.952   0.995   1.350   1.129   1.155   1.165   0.850   0.900
20    L        -0.648  -0.663  -0.634  -0.633  -0.650  -0.600  -0.698  -0.709  -0.640
21    G         1.961   2.079   2.157   2.097   2.271   2.396   2.181   2.368   2.506
22    L        -0.091   0.103  -0.012  -0.266   0.026  -0.100  -0.359  -0.099  -0.226
23    V         1.961   2.079   2.157   1.931   2.064   2.225   2.181   2.368   2.506
24    V        -0.091  -0.100  -0.039  -0.210  -0.250  -0.102  -0.359  -0.345  -0.263
25    S         0.334   0.065   0.096   0.591   0.225   0.258   0.318  -0.077  -0.043
26    Q         0.334   0.065   0.096   0.472   0.112   0.102   0.318  -0.077  -0.043
27    G         1.961   2.079   2.157   2.097   2.271   2.396   2.181   2.368   2.506
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    K         1.123   0.952   0.995   0.845   0.643   0.645   1.165   0.850   0.900
30    M         0.334   0.065   0.096   0.742   0.344   0.392   0.318  -0.077  -0.043
31    Q        -1.053  -1.164  -1.136  -0.807  -0.952  -0.928  -0.867  -0.961  -0.902
32    K         1.961   2.079   2.157   1.609   1.806   1.894   2.181   2.368   2.506
33    T         1.123   1.080   0.949   1.381   1.353   1.143   1.165   1.079   0.813
34    V         1.123   1.080   0.949   1.187   1.091   0.930   1.165   1.079   0.813
35    K         1.961   2.079   2.157   1.609   1.806   1.894   2.181   2.368   2.506
36    V         1.961   2.079   2.157   1.931   2.064   2.225   2.181   2.368   2.506
37    R         1.961   2.079   2.157   1.956   2.135   2.251   2.181   2.368   2.506
38    V         1.961   2.079   2.157   1.931   2.064   2.225   2.181   2.368   2.506
39    E        -0.648  -0.783  -0.670  -0.708  -0.847  -0.671  -0.698  -0.813  -0.677
40    T        -0.244  -0.217  -0.126  -0.207  -0.209  -0.049  -0.529  -0.491  -0.372
41    K         0.008  -0.141  -0.032  -0.332  -0.541  -0.378  -0.190  -0.386  -0.249
42    V         0.008   0.002  -0.027  -0.180  -0.387  -0.320  -0.190  -0.235  -0.244
43    F         0.565   0.638   0.715   0.618   0.717   0.845   0.149   0.241   0.345
44    N         0.008  -0.079  -0.016   0.178   0.070   0.165  -0.190  -0.310  -0.226
45    K         0.334   0.323   0.094   0.233   0.246  -0.040   0.318   0.302  -0.045
46    K        -0.648  -0.768  -0.638  -0.745  -0.908  -0.728  -0.698  -0.796  -0.642
47    I         0.008  -0.085  -0.012  -0.097  -0.247  -0.160  -0.190  -0.299  -0.213
48    N        -1.053  -1.164  -1.136  -0.667  -0.833  -0.808  -0.867  -0.961  -0.902
49    K         1.961   2.079   2.157   1.609   1.806   1.894   2.181   2.368   2.506
50    E         1.123   0.952   0.995   1.052   0.858   0.922   1.165   0.850   0.900
51    L        -0.648  -0.717  -0.656  -0.726  -0.746  -0.704  -0.698  -0.756  -0.663
52    F        -1.610  -1.600  -1.550  -1.178  -1.148  -1.093  -1.206  -1.165  -1.081
53    H        -1.206  -1.252  -1.144  -1.021  -1.088  -0.913  -1.037  -1.041  -0.912
54    R         0.334   0.065   0.096   0.593   0.241   0.318   0.318  -0.077  -0.043
55    R         0.738   0.816   0.760   0.322   0.435   0.322   0.487   0.595   0.438
56    D         1.123   0.952   0.995   1.298   1.050   1.124   1.165   0.850   0.900
57    Y         0.738   0.812   0.760   0.949   1.059   0.941   0.487   0.586   0.438
58    L         1.123   1.080   0.949   1.113   1.202   0.918   1.165   1.079   0.813
59    V         1.123   1.080   0.949   1.220   1.138   1.003   1.165   1.079   0.813
60    H         1.961   2.079   2.157   2.206   2.393   2.509   2.181   2.368   2.506
61    D         1.961   2.079   2.157   2.036   2.208   2.334   2.181   2.368   2.506
62    E         1.123   0.952   0.995   1.047   0.849   0.911   1.165   0.850   0.900
63    G        -0.396  -0.530  -0.559   0.040  -0.148  -0.168  -0.359  -0.531  -0.539
64    E        -0.648  -0.668  -0.651  -0.623  -0.547  -0.538  -0.698  -0.702  -0.658
65    I        -1.053  -1.120  -1.096  -0.909  -1.033  -0.992  -0.867  -0.924  -0.862
66    S        -0.648  -0.586  -0.613  -0.305  -0.191  -0.247  -0.698  -0.604  -0.610
67    R         0.008   0.005  -0.035  -0.167  -0.161  -0.294  -0.190  -0.172  -0.247
68    E         1.123   0.952   0.995   1.014   0.773   0.848   1.165   0.850   0.900
69    G         1.961   2.079   2.157   2.097   2.271   2.396   2.181   2.368   2.506
70    D         1.961   2.079   2.157   2.036   2.208   2.334   2.181   2.368   2.506
71    L        -0.244  -0.190  -0.121  -0.552  -0.447  -0.372  -0.529  -0.453  -0.365
72    V         1.961   2.079   2.157   1.931   2.064   2.225   2.181   2.368   2.506
73    R         1.123   0.952   0.995   1.227   0.973   1.060   1.165   0.850   0.900
74    I         1.961   2.079   2.157   1.908   2.096   2.202   2.181   2.368   2.506
75    E         0.334   0.212   0.133   0.335   0.195   0.082   0.318   0.125   0.015
76    A        -0.396  -0.587  -0.583  -0.095  -0.421  -0.351  -0.359  -0.591  -0.569
77    T        -0.648  -0.783  -0.670  -0.381  -0.549  -0.368  -0.698  -0.813  -0.677
78    R         0.008  -0.085  -0.012   0.128  -0.001   0.131  -0.190  -0.299  -0.213
79    P         0.008  -0.085  -0.012   0.032  -0.123  -0.060  -0.190  -0.299  -0.213
80    L        -0.091  -0.150  -0.033  -0.302  -0.270  -0.165  -0.359  -0.400  -0.249
81    S         1.961   2.079   2.157   2.018   2.224   2.315   2.181   2.368   2.506
82    K         1.123   1.262   0.985   0.879   1.082   0.696   1.165   1.383   0.881
83    R        -0.396  -0.527  -0.557  -0.063  -0.284  -0.241  -0.359  -0.528  -0.537
84    K         1.961   2.079   2.157   1.609   1.806   1.894   2.181   2.368   2.506
85    F        -1.610  -1.600  -1.550  -1.055  -1.101  -0.948  -1.206  -1.165  -1.081
86    F         1.123   0.952   0.995   1.415   1.211   1.282   1.165   0.850   0.900
87    A         0.334   0.289   0.155   0.543   0.371   0.288   0.318   0.224   0.047
88    I         0.565   0.628   0.715   0.283   0.310   0.488   0.149   0.220   0.345
89    A         1.123   0.952   0.995   1.201   0.867   0.974   1.165   0.850   0.900
90    E         0.334   0.212   0.133   0.358   0.209   0.123   0.318   0.125   0.015
91    I         1.961   2.079   2.157   1.908   2.096   2.202   2.181   2.368   2.506
92    I         0.565   0.638   0.715   0.083   0.167   0.240   0.149   0.241   0.345
93    R        -1.053  -1.164  -1.136  -0.833  -1.079  -0.973  -0.867  -0.961  -0.902
94    N         0.334   0.065   0.096   0.684   0.343   0.365   0.318  -0.077  -0.043
95    K         0.334   0.065   0.096   0.158  -0.237  -0.179   0.318  -0.077  -0.043
96    G         1.961   2.079   2.157   2.097   2.271   2.396   2.181   2.368   2.506
97    Q         1.123   0.952   0.995   1.235   1.031   1.087   1.165   0.850   0.900
98    Q         0.334   0.065   0.096   0.492   0.115   0.140   0.318  -0.077  -0.043
99    F         0.334   0.065   0.096   0.707   0.322   0.392   0.318  -0.077  -0.043
100   A         0.334   0.065   0.096   0.465  -0.016   0.045   0.318  -0.077  -0.043
101   L         0.008  -0.141  -0.032  -0.179  -0.389  -0.269  -0.190  -0.386  -0.249
102   Y         0.008  -0.014   0.039   0.288   0.257   0.339  -0.190  -0.192  -0.136
103   E         0.008  -0.123  -0.018  -0.155  -0.308  -0.164  -0.190  -0.357  -0.227
104   S        -0.648  -0.769  -0.641  -0.706  -0.868  -0.731  -0.698  -0.797  -0.647
105   E        -1.610  -1.597  -1.551  -1.453  -1.440  -1.379  -1.206  -1.163  -1.082
106   A         1.123   0.952   0.995   1.293   1.028   1.156   1.165   0.850   0.900
107   Q        -0.396  -0.520  -0.556  -0.465  -0.614  -0.648  -0.359  -0.520  -0.535
108   L        -1.610  -1.475  -1.519  -1.674  -1.369  -1.554  -1.206  -1.056  -1.056
109   S        -1.610  -1.469  -1.516  -1.444  -1.204  -1.323  -1.206  -1.052  -1.054
110   V         1.123   0.952   0.995   1.160   0.848   0.954   1.165   0.850   0.900
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   A        -0.396  -0.303  -0.547  -0.330  -0.249  -0.671  -0.359  -0.234  -0.524
115   K        -0.396  -0.305  -0.551  -0.620  -0.480  -0.891  -0.359  -0.237  -0.530
116   E         0.738   0.658   0.742   0.484   0.328   0.466   0.487   0.283   0.402
117   E         0.008  -0.095  -0.028  -0.152  -0.318  -0.178  -0.190  -0.336  -0.244
118   A        -1.610  -1.475  -1.519  -1.369  -1.282  -1.239  -1.206  -1.056  -1.056
119   Q        -0.244  -0.031  -0.073  -0.796  -0.467  -0.570  -0.529  -0.219  -0.297
120   K        -0.396  -0.587  -0.583  -0.586  -0.898  -0.883  -0.359  -0.591  -0.569
121   A        -0.091   0.004  -0.024  -0.071   0.001   0.035  -0.359  -0.231  -0.244
122   K         0.334   0.323   0.094   0.158   0.180  -0.181   0.318   0.302  -0.045
123   E        -0.801  -0.659  -0.677  -1.195  -1.029  -1.005  -0.867  -0.702  -0.687
124   F         1.961   2.079   2.157   2.110   2.309   2.410   2.181   2.368   2.506
125   L         0.188   0.086   0.026   0.150   0.025  -0.093   0.106  -0.049  -0.147
126   D         0.188   0.174   0.054   0.095   0.051  -0.106   0.106   0.071  -0.105
127   K        -0.578  -0.597  -0.625  -0.444  -0.464  -0.538  -0.585  -0.600  -0.619
128   R         1.040   0.941   0.919   1.059   0.893   0.806   1.028   0.830   0.755
129   S         0.188   0.331   0.088   0.005   0.197  -0.195   0.106   0.318  -0.054
130   V        -1.700  -1.642  -1.571  -1.796  -1.748  -1.614  -1.276  -1.192  -1.096
131   R        -1.228  -1.229  -1.171  -1.016  -0.988  -0.925  -1.046  -1.018  -0.934
132   E        -0.578  -0.415  -0.573  -0.722  -0.479  -0.737  -0.585  -0.363  -0.556
133   N        -0.756  -0.779  -0.683  -0.772  -0.875  -0.726  -0.815  -0.811  -0.690
134   K        -1.327  -1.272  -1.191  -1.252  -1.187  -1.053  -1.138  -1.054  -0.952
135   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   E        -0.761  -0.629  -0.662  -0.838  -0.690  -0.687  -0.806  -0.640  -0.663
138   K        -1.327  -1.221  -1.191  -1.495  -1.350  -1.303  -1.138  -1.011  -0.952
139   T        -1.206  -1.216  -1.156  -1.204  -1.298  -1.163  -1.037  -1.015  -0.922
140   T        -0.648  -0.622  -0.626  -0.483  -0.531  -0.464  -0.698  -0.663  -0.633
141   L         0.008   0.005  -0.035  -0.158  -0.069  -0.231  -0.190  -0.172  -0.247
142   L         0.334   0.212   0.133   0.344   0.252   0.050   0.318   0.125   0.015
143   R        -1.053  -0.691  -1.019  -1.079  -0.546  -1.037  -0.867  -0.439  -0.783
144   D         0.334   0.065   0.096   0.511   0.036   0.091   0.318  -0.077  -0.043
145   I        -0.648  -0.583  -0.612  -0.697  -0.495  -0.613  -0.698  -0.602  -0.609
146   R        -0.091  -0.168  -0.031  -0.452  -0.545  -0.353  -0.359  -0.429  -0.253
147   T        -1.610  -1.571  -1.532  -1.341  -1.384  -1.249  -1.206  -1.145  -1.067
148   I        -1.053  -1.109  -1.099  -0.919  -0.994  -0.966  -0.867  -0.914  -0.866
149   Q        -0.648  -0.783  -0.670  -0.620  -0.905  -0.671  -0.698  -0.813  -0.677
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   D        -0.756  -0.650  -0.671  -1.092  -0.947  -0.922  -0.815  -0.674  -0.677
155   A        -1.228  -1.232  -1.168  -0.919  -0.912  -0.820  -1.046  -1.021  -0.931
156   L        -1.700  -1.642  -1.571  -1.480  -1.447  -1.288  -1.276  -1.192  -1.096
157   S         0.188   0.172   0.051   0.458   0.453   0.299   0.106   0.069  -0.109
158   S        -1.228  -1.192  -1.147  -1.197  -1.221  -1.114  -1.046  -0.985  -0.911
159   G         0.188   0.236   0.049   0.486   0.565   0.279   0.106   0.181  -0.113
160   S        -1.228  -1.193  -1.148  -0.956  -0.906  -0.831  -1.046  -0.986  -0.913
161   T        -1.228  -1.190  -1.145  -1.149  -1.114  -1.002  -1.046  -0.983  -0.910
162   P         0.188   0.414   0.101   0.389   0.723   0.245   0.106   0.443  -0.034
163   K        -1.700  -1.642  -1.571  -1.507  -1.422  -1.316  -1.276  -1.192  -1.096
164   -        -0.761  -0.661  -0.665  -0.748  -0.602  -0.625  -0.806  -0.667  -0.666
165   -        -0.163  -0.121  -0.100  -0.262  -0.229  -0.233  -0.412  -0.351  -0.335
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -         0.019  -0.069   0.002  -0.054  -0.152  -0.101  -0.142  -0.277  -0.184
169   -        -1.327  -1.264  -1.191  -1.684  -1.562  -1.499  -1.138  -1.048  -0.952
170   -        -1.327  -1.264  -1.191  -1.326  -1.234  -1.130  -1.138  -1.048  -0.952
171   E         1.040   1.035   0.927   0.903   0.910   0.727   1.028   1.000   0.770
172   L        -0.244  -0.167  -0.116  -0.552  -0.395  -0.373  -0.529  -0.420  -0.358
173   L        -1.206  -1.127  -1.134  -1.358  -1.220  -1.291  -1.037  -0.945  -0.903
174   E        -0.648  -0.507  -0.632  -0.887  -0.701  -0.878  -0.698  -0.533  -0.637
175   I         1.123   0.952   0.995   1.173   0.939   1.001   1.165   0.850   0.900
176   K         1.123   0.952   0.995   0.914   0.734   0.781   1.165   0.850   0.900
177   Q        -0.648  -0.642  -0.628  -0.708  -0.739  -0.666  -0.698  -0.677  -0.630
178   R         0.008   0.005  -0.035  -0.103  -0.081  -0.184  -0.190  -0.172  -0.247
179   Y         1.123   0.952   0.995   1.512   1.312   1.378   1.165   0.850   0.900
180   G         0.008  -0.085  -0.012   0.189   0.031   0.160  -0.190  -0.299  -0.213
181   I         0.738   0.738   0.778   0.599   0.539   0.609   0.487   0.442   0.474
182   Q        -0.801  -0.813  -0.692  -1.010  -1.031  -0.832  -0.867  -0.845  -0.701
183   D        -0.648  -0.456  -0.609  -0.747  -0.504  -0.729  -0.698  -0.490  -0.612
184   F        -0.091  -0.150  -0.033   0.137   0.059   0.249  -0.359  -0.400  -0.249
185   S        -0.648  -0.586  -0.613  -0.347  -0.292  -0.270  -0.698  -0.604  -0.610
186   Q        -1.053  -1.015  -1.083  -0.524  -0.467  -0.560  -0.867  -0.817  -0.849
187   E        -0.801  -0.814  -0.690  -0.790  -0.762  -0.606  -0.867  -0.845  -0.700
188   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   R        -0.091   0.077  -0.030  -0.618  -0.395  -0.518  -0.359  -0.154  -0.251
191   Q        -0.648  -0.715  -0.653  -0.570  -0.727  -0.577  -0.698  -0.753  -0.660
192   L        -0.648  -0.444  -0.586  -0.697  -0.335  -0.573  -0.698  -0.416  -0.578
193   L        -0.648  -0.669  -0.634  -0.761  -0.762  -0.730  -0.698  -0.704  -0.640
194   Q        -1.206  -1.252  -1.144  -1.244  -1.233  -1.123  -1.037  -1.041  -0.912
195   L         1.961   2.079   2.157   1.804   2.104   2.095   2.181   2.368   2.506
196   D        -0.578  -0.661  -0.665  -0.388  -0.540  -0.564  -0.585  -0.672  -0.666
197   I        -0.106  -0.083  -0.072  -0.322  -0.327  -0.310  -0.354  -0.328  -0.303
198   S        -1.228  -1.145  -1.161  -1.164  -1.070  -1.114  -1.046  -0.941  -0.925
199   G        -0.756  -0.732  -0.693  -0.940  -0.942  -0.896  -0.815  -0.767  -0.700
200   L        -1.228  -1.123  -1.131  -1.143  -0.988  -0.989  -1.046  -0.910  -0.897
201   E        -0.578  -0.661  -0.665  -0.656  -0.796  -0.778  -0.585  -0.672  -0.666
202   V        -1.700  -1.642  -1.571  -1.601  -1.495  -1.412  -1.276  -1.192  -1.096
203   N        -1.228  -1.188  -1.146  -1.073  -1.076  -0.969  -1.046  -0.982  -0.911
204   L        -0.578  -0.599  -0.629  -0.549  -0.557  -0.604  -0.585  -0.602  -0.624
205   E        -1.228  -1.191  -1.144  -1.378  -1.313  -1.260  -1.046  -0.984  -0.909
206   K        -0.761  -0.638  -0.660  -1.154  -0.983  -1.020  -0.806  -0.644  -0.660
207   Q        -0.578  -0.661  -0.665  -0.609  -0.746  -0.829  -0.585  -0.672  -0.666
208   R        -1.228  -1.192  -1.147  -1.250  -1.158  -1.153  -1.046  -0.985  -0.911
209   S        -0.648  -0.576  -0.621  -0.617  -0.511  -0.602  -0.698  -0.609  -0.626
210   L        -0.244  -0.164  -0.114  -0.754  -0.595  -0.576  -0.529  -0.415  -0.356
211   I        -0.091   0.061  -0.005  -0.285  -0.071  -0.146  -0.359  -0.134  -0.209
212   D         0.334   0.329   0.087   0.626   0.604   0.295   0.318   0.309  -0.056
213   R        -0.578  -0.481  -0.607  -0.310  -0.166  -0.349  -0.585  -0.447  -0.597
214   I         0.188   0.166   0.053   0.353   0.315   0.188   0.106   0.060  -0.107
215   Q        -0.578  -0.595  -0.621  -0.470  -0.491  -0.547  -0.585  -0.598  -0.614
216   T        -1.700  -1.642  -1.571  -1.282  -1.172  -1.085  -1.276  -1.192  -1.096
217   R        -0.756  -0.731  -0.692  -1.102  -1.080  -1.008  -0.815  -0.766  -0.699
218   L         1.040   0.941   0.919   0.935   0.815   0.742   1.028   0.830   0.755
219   S        -0.578  -0.403  -0.572  -0.382  -0.114  -0.403  -0.585  -0.349  -0.556
220   E         0.188   0.322   0.094   0.015   0.195  -0.168   0.106   0.305  -0.044
221   L         0.938   1.068   0.883   0.848   1.049   0.786   0.853   1.057   0.683
222   L        -0.194  -0.105  -0.100  -0.229  -0.065  -0.068  -0.474  -0.350  -0.338
223   S        -0.761  -0.708  -0.678  -0.807  -0.713  -0.720  -0.806  -0.725  -0.682
224   N         0.586   0.666   0.726   0.355   0.474   0.514   0.189   0.298   0.367
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   D        -0.756  -0.665  -0.661  -0.696  -0.550  -0.536  -0.815  -0.696  -0.668
229   L        -0.578  -0.597  -0.625  -0.515  -0.566  -0.654  -0.585  -0.600  -0.619
230   K        -0.578  -0.482  -0.605  -0.773  -0.642  -0.803  -0.585  -0.449  -0.595
231   C        -0.284  -0.212  -0.121  -0.212  -0.134   0.017  -0.585  -0.484  -0.366
232   D        -1.700  -1.642  -1.571  -1.742  -1.737  -1.558  -1.276  -1.192  -1.096
233   Q        -0.106  -0.032  -0.046  -0.381  -0.280  -0.287  -0.354  -0.241  -0.266
234   F        -0.756  -0.735  -0.691  -0.526  -0.497  -0.385  -0.815  -0.770  -0.698
235   L         1.040   1.118   0.946   0.939   1.080   0.794   1.028   1.144   0.807
236   K        -1.228  -1.229  -1.171  -1.579  -1.575  -1.494  -1.046  -1.018  -0.934
237   D        -0.756  -0.741  -0.670  -0.757  -0.789  -0.651  -0.815  -0.777  -0.677
238   H        -0.756  -0.615  -0.658  -1.033  -0.849  -0.862  -0.815  -0.643  -0.664
239   G         0.188   0.236   0.049   0.411   0.487   0.156   0.106   0.181  -0.113
240   V        -0.756  -0.732  -0.693  -1.024  -0.989  -0.928  -0.815  -0.767  -0.700
241   E        -0.578  -0.661  -0.665  -0.722  -0.871  -0.879  -0.585  -0.672  -0.666
242   D        -1.228  -1.186  -1.144  -0.850  -0.791  -0.706  -1.046  -0.980  -0.909
243   P        -0.578  -0.661  -0.665  -0.279  -0.486  -0.487  -0.585  -0.672  -0.666
244   L        -0.578  -0.527  -0.607  -0.689  -0.608  -0.744  -0.585  -0.519  -0.597
245   T        -0.756  -0.731  -0.692  -0.939  -0.884  -0.797  -0.815  -0.766  -0.699
246   L         0.188   0.086   0.026   0.139  -0.002  -0.112   0.106  -0.049  -0.147
247   K        -0.106  -0.079  -0.055  -0.490  -0.462  -0.395  -0.354  -0.320  -0.280
248   K         1.040   1.123   0.950   0.817   0.937   0.722   1.028   1.153   0.814
249   N         0.019  -0.011  -0.060   0.222   0.189   0.085  -0.142  -0.188  -0.276
250   I         0.938   0.979   0.868   0.945   1.000   0.836   0.853   0.899   0.655
251   K        -0.194  -0.101  -0.099  -0.503  -0.356  -0.323  -0.474  -0.345  -0.336
252   K         1.040   0.941   0.919   0.769   0.624   0.585   1.028   0.830   0.755
253   N         1.961   2.079   2.157   2.076   2.284   2.374   2.181   2.368   2.506
254   L        -0.106   0.001  -0.018  -0.322  -0.134  -0.184  -0.354  -0.187  -0.219
255   L         0.660   0.772   0.762   0.354   0.536   0.477   0.337   0.510   0.442
256   R         1.040   0.941   0.919   1.140   1.018   0.964   1.028   0.830   0.755
257   K         1.040   1.118   0.946   0.769   0.880   0.628   1.028   1.144   0.807
258   H         0.019  -0.011  -0.060   0.428   0.398   0.304  -0.142  -0.188  -0.276
259   V        -0.194  -0.167  -0.090  -0.442  -0.433  -0.316  -0.474  -0.426  -0.324
260   M         0.938   1.083   0.885   0.848   1.069   0.790   0.853   1.084   0.688
261   M        -0.761  -0.638  -0.692  -0.821  -0.626  -0.772  -0.806  -0.639  -0.698
262   D        -0.761  -0.747  -0.702  -0.736  -0.701  -0.597  -0.806  -0.771  -0.709
263   M        -0.194  -0.099  -0.099  -0.351  -0.205  -0.177  -0.474  -0.343  -0.337
264   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   P         0.812   0.902   0.860   0.700   0.833   0.769   0.625   0.757   0.639
271   S        -0.871  -0.812  -0.727  -0.739  -0.663  -0.525  -0.931  -0.843  -0.736
272   Q        -0.163  -0.108  -0.069  -0.301  -0.238  -0.182  -0.412  -0.337  -0.289
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03246
Output conservation file - output/Q03246
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
