1     M         1.606   1.607   1.661   1.766   1.768   1.853   1.748   1.750   1.829
2     -         0.310   0.253   0.295   0.132   0.029   0.095   0.071  -0.031   0.022
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -         0.310   0.253   0.295   0.124   0.025   0.084   0.071  -0.031   0.022
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    F        -0.632  -0.629  -0.554  -0.723  -0.713  -0.600  -0.767  -0.764  -0.657
22    V        -0.632  -0.629  -0.554  -0.632  -0.629  -0.511  -0.767  -0.764  -0.657
23    A        -0.632  -0.629  -0.554  -0.817  -0.816  -0.693  -0.767  -0.764  -0.657
24    L        -0.632  -0.629  -0.554  -0.939  -0.930  -0.814  -0.767  -0.764  -0.657
25    K        -0.632  -0.629  -0.554  -0.882  -0.880  -0.758  -0.767  -0.764  -0.657
26    R        -0.632  -0.629  -0.554  -0.616  -0.607  -0.495  -0.767  -0.764  -0.657
27    L         1.606   1.607   1.661   1.389   1.388   1.480   1.748   1.750   1.829
28    L         0.310   0.331   0.316   0.083   0.128   0.060   0.071   0.110   0.061
29    V        -0.632  -0.629  -0.554  -0.786  -0.782  -0.663  -0.767  -0.764  -0.657
30    E        -0.632  -0.629  -0.554  -0.522  -0.517  -0.402  -0.767  -0.764  -0.657
31    T        -0.632  -0.629  -0.554  -0.709  -0.706  -0.587  -0.767  -0.764  -0.657
32    K        -0.632  -0.629  -0.554  -0.763  -0.754  -0.640  -0.767  -0.764  -0.657
33    E         1.606   1.607   1.661   1.632   1.634   1.720   1.748   1.750   1.829
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    Q         0.310   0.331   0.316   0.271   0.305   0.279   0.071   0.110   0.061
39    M         0.310   0.288   0.304   0.269   0.225   0.220   0.071   0.032   0.039
40    C        -0.512  -0.524  -0.502  -0.486  -0.512  -0.452  -0.610  -0.629  -0.590
41    F        -0.512  -0.488  -0.495  -0.701  -0.661  -0.698  -0.610  -0.578  -0.581
42    A        -1.218  -1.208  -1.134  -1.112  -1.101  -0.984  -1.082  -1.072  -0.968
43    V        -1.218  -1.208  -1.134  -1.401  -1.378  -1.268  -1.082  -1.072  -0.968
44    K        -0.512  -0.474  -0.489  -0.593  -0.526  -0.553  -0.610  -0.560  -0.573
45    S        -0.512  -0.555  -0.514  -0.518  -0.577  -0.503  -0.610  -0.668  -0.606
46    I        -0.512  -0.537  -0.505  -0.675  -0.729  -0.674  -0.610  -0.645  -0.594
47    F        -0.512  -0.488  -0.495  -0.562  -0.524  -0.541  -0.610  -0.578  -0.581
48    Q        -0.512  -0.537  -0.505  -0.417  -0.456  -0.431  -0.610  -0.645  -0.594
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    R        -1.107  -1.109  -1.090  -1.033  -1.033  -1.010  -0.968  -0.970  -0.924
57    V         0.235   0.245   0.280  -0.098  -0.086  -0.022  -0.063  -0.045  -0.004
58    F        -1.107  -1.112  -1.099  -0.926  -0.935  -0.899  -0.968  -0.973  -0.933
59    A        -0.543  -0.540  -0.509  -0.525  -0.524  -0.478  -0.667  -0.663  -0.605
60    W        -1.107  -1.110  -1.107  -1.090  -1.102  -1.048  -0.968  -0.972  -0.942
61    V        -0.329  -0.357  -0.437  -0.160  -0.200  -0.305  -0.365  -0.402  -0.503
62    M        -1.107  -1.110  -1.107  -1.019  -1.028  -1.018  -0.968  -0.972  -0.942
63    S        -1.107  -1.112  -1.099  -1.098  -1.105  -1.074  -0.968  -0.973  -0.933
64    L        -0.329  -0.323  -0.429  -0.362  -0.354  -0.558  -0.365  -0.357  -0.493
65    S        -0.543  -0.527  -0.518  -0.521  -0.500  -0.490  -0.667  -0.650  -0.614
66    L        -0.329  -0.357  -0.437  -0.383  -0.425  -0.517  -0.365  -0.402  -0.503
67    F         0.587   0.573   0.439   0.618   0.595   0.372   0.541   0.518   0.279
68    S        -1.107  -1.109  -1.090  -1.065  -1.071  -1.026  -0.968  -0.970  -0.924
69    W        -1.107  -1.110  -1.107  -0.860  -0.871  -0.861  -0.968  -0.972  -0.942
70    F        -1.107  -1.123  -1.081  -1.142  -1.176  -1.115  -0.968  -0.984  -0.915
71    Y        -1.672  -1.670  -1.584  -1.548  -1.553  -1.414  -1.270  -1.268  -1.154
72    V        -1.672  -1.670  -1.584  -1.442  -1.441  -1.309  -1.270  -1.268  -1.154
73    N        -1.672  -1.670  -1.584  -1.554  -1.552  -1.419  -1.270  -1.268  -1.154
74    L        -0.543  -0.549  -0.519  -0.804  -0.819  -0.770  -0.667  -0.673  -0.616
75    Q        -0.329  -0.321  -0.439  -0.122  -0.105  -0.330  -0.365  -0.353  -0.507
76    N        -1.107  -1.110  -1.107  -0.952  -0.955  -0.956  -0.968  -0.972  -0.942
77    I        -0.329  -0.319  -0.435  -0.255  -0.238  -0.425  -0.365  -0.351  -0.502
78    L        -1.107  -1.112  -1.099  -1.194  -1.203  -1.160  -0.968  -0.973  -0.933
79    I         0.235   0.231   0.275  -0.020  -0.030   0.043  -0.063  -0.071  -0.014
80    K        -1.107  -1.110  -1.107  -1.162  -1.166  -1.160  -0.968  -0.972  -0.942
81    A        -0.543  -0.540  -0.511  -0.587  -0.588  -0.524  -0.667  -0.664  -0.606
82    L        -0.329  -0.321  -0.439  -0.437  -0.428  -0.594  -0.365  -0.353  -0.507
83    R         0.587   0.595   0.444   0.637   0.655   0.406   0.541   0.554   0.288
84    V        -0.329  -0.323  -0.429  -0.201  -0.193  -0.351  -0.365  -0.357  -0.493
85    G         0.587   0.591   0.444   0.756   0.759   0.514   0.541   0.546   0.289
86    P         1.606   1.607   1.661   1.720   1.721   1.807   1.748   1.750   1.829
87    V         0.235   0.239   0.290   0.013   0.018   0.094  -0.063  -0.056   0.013
88    P         1.606   1.607   1.661   1.720   1.721   1.807   1.748   1.750   1.829
89    E        -1.107  -1.110  -1.107  -1.074  -1.073  -1.065  -0.968  -0.972  -0.942
90    H         1.606   1.607   1.661   1.822   1.828   1.908   1.748   1.750   1.829
91    V        -0.329  -0.343  -0.429  -0.351  -0.378  -0.549  -0.365  -0.383  -0.494
92    S        -0.543  -0.540  -0.507  -0.587  -0.587  -0.511  -0.667  -0.664  -0.602
93    F        -0.329  -0.321  -0.439  -0.283  -0.272  -0.470  -0.365  -0.353  -0.507
94    I         1.606   1.607   1.661   1.516   1.515   1.605   1.748   1.750   1.829
95    M         1.606   1.607   1.661   1.766   1.768   1.853   1.748   1.750   1.829
96    D         1.606   1.607   1.661   1.676   1.680   1.764   1.748   1.750   1.829
97    G         1.606   1.607   1.661   1.753   1.754   1.840   1.748   1.750   1.829
98    N         1.606   1.607   1.661   1.673   1.677   1.760   1.748   1.750   1.829
99    R         1.606   1.607   1.661   1.626   1.632   1.714   1.748   1.750   1.829
100   R         0.587   0.595   0.444   0.657   0.673   0.437   0.541   0.554   0.288
101   Y         0.587   0.573   0.439   0.752   0.729   0.514   0.541   0.518   0.279
102   A         1.606   1.607   1.661   1.713   1.714   1.800   1.748   1.750   1.829
103   K         1.606   1.607   1.661   1.554   1.559   1.643   1.748   1.750   1.829
104   S         0.235   0.232   0.275  -0.058  -0.064  -0.001  -0.063  -0.069  -0.014
105   R        -1.107  -1.099  -1.075  -1.100  -1.088  -1.049  -0.968  -0.960  -0.909
106   R         0.235   0.247   0.281   0.116   0.142   0.179  -0.063  -0.042  -0.004
107   L        -1.107  -1.123  -1.081  -1.119  -1.142  -1.057  -0.968  -0.984  -0.915
108   P         0.587   0.591   0.444   0.742   0.747   0.513   0.541   0.546   0.289
109   V         0.235   0.238   0.281  -0.098  -0.098  -0.022  -0.063  -0.059  -0.004
110   K         0.587   0.573   0.439   0.584   0.568   0.357   0.541   0.518   0.279
111   K        -0.543  -0.540  -0.511  -0.672  -0.664  -0.606  -0.667  -0.664  -0.606
112   G         1.606   1.607   1.661   1.753   1.754   1.840   1.748   1.750   1.829
113   H         1.606   1.607   1.661   1.822   1.828   1.908   1.748   1.750   1.829
114   E        -1.107  -1.112  -1.099  -1.046  -1.049  -1.033  -0.968  -0.973  -0.933
115   A         1.606   1.607   1.661   1.713   1.714   1.800   1.748   1.750   1.829
116   G         1.606   1.607   1.661   1.753   1.754   1.840   1.748   1.750   1.829
117   G         0.235   0.239   0.290   0.231   0.236   0.312  -0.063  -0.056   0.013
118   L        -1.672  -1.670  -1.584  -1.564  -1.556  -1.430  -1.270  -1.268  -1.154
119   T        -0.329  -0.321  -0.439  -0.251  -0.241  -0.435  -0.365  -0.353  -0.507
120   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
121   L        -0.543  -0.538  -0.512  -0.846  -0.844  -0.777  -0.667  -0.661  -0.608
122   T        -1.107  -1.112  -1.099  -0.969  -0.975  -0.953  -0.968  -0.973  -0.933
123   L        -0.543  -0.552  -0.524  -0.804  -0.822  -0.775  -0.667  -0.676  -0.622
124   L         0.587   0.573   0.439   0.457   0.433   0.238   0.541   0.518   0.279
125   Y        -1.107  -1.112  -1.099  -0.870  -0.874  -0.861  -0.968  -0.973  -0.933
126   I        -0.329  -0.321  -0.439  -0.356  -0.346  -0.525  -0.365  -0.353  -0.507
127   C         1.606   1.607   1.661   1.868   1.870   1.953   1.748   1.750   1.829
128   K        -0.543  -0.552  -0.524  -0.601  -0.611  -0.568  -0.667  -0.676  -0.622
129   R        -0.543  -0.549  -0.519  -0.670  -0.674  -0.619  -0.667  -0.673  -0.616
130   L         0.587   0.595   0.444   0.457   0.465   0.246   0.541   0.554   0.288
131   G         0.587   0.567   0.434   0.792   0.762   0.553   0.541   0.509   0.271
132   V         0.235   0.239   0.290   0.013   0.018   0.094  -0.063  -0.056   0.013
133   K        -1.107  -1.112  -1.099  -1.242  -1.250  -1.248  -0.968  -0.973  -0.933
134   C        -1.107  -1.112  -1.099  -0.741  -0.752  -0.744  -0.968  -0.973  -0.933
135   V         0.587   0.573   0.439   0.631   0.608   0.385   0.541   0.518   0.279
136   S         0.235   0.239   0.290  -0.010  -0.006   0.078  -0.063  -0.056   0.013
137   A        -0.329  -0.321  -0.439  -0.206  -0.195  -0.408  -0.365  -0.353  -0.507
138   Y         1.606   1.607   1.661   1.727   1.727   1.813   1.748   1.750   1.829
139   A         1.606   1.607   1.661   1.713   1.714   1.800   1.748   1.750   1.829
140   F         1.606   1.607   1.661   1.615   1.617   1.704   1.748   1.750   1.829
141   S         1.606   1.607   1.661   1.522   1.522   1.612   1.748   1.750   1.829
142   I         0.587   0.595   0.444   0.496   0.506   0.252   0.541   0.554   0.288
143   E         1.606   1.607   1.661   1.602   1.606   1.690   1.748   1.750   1.829
144   N         1.606   1.607   1.661   1.673   1.677   1.760   1.748   1.750   1.829
145   F         1.606   1.607   1.661   1.615   1.617   1.704   1.748   1.750   1.829
146   N         1.606   1.607   1.661   1.673   1.677   1.760   1.748   1.750   1.829
147   R         1.606   1.607   1.661   1.626   1.632   1.714   1.748   1.750   1.829
148   P         0.235   0.240   0.284   0.040   0.044   0.121  -0.063  -0.055   0.003
149   K        -0.329  -0.357  -0.437  -0.294  -0.330  -0.453  -0.365  -0.402  -0.503
150   E         0.587   0.567   0.434   0.675   0.650   0.463   0.541   0.509   0.271
151   E         1.606   1.607   1.661   1.602   1.606   1.690   1.748   1.750   1.829
152   V         1.606   1.607   1.661   1.629   1.630   1.717   1.748   1.750   1.829
153   D        -0.329  -0.357  -0.437  -0.189  -0.229  -0.363  -0.365  -0.402  -0.503
154   T         1.606   1.607   1.661   1.636   1.636   1.724   1.748   1.750   1.829
155   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
156   M         0.235   0.239   0.290   0.188   0.194   0.267  -0.063  -0.056   0.013
157   N        -0.543  -0.552  -0.524  -0.536  -0.549  -0.507  -0.667  -0.676  -0.622
158   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
159   F         0.235   0.240   0.284  -0.106  -0.103  -0.025  -0.063  -0.055   0.003
160   T        -0.543  -0.527  -0.518  -0.529  -0.505  -0.481  -0.667  -0.650  -0.614
161   V        -0.329  -0.323  -0.429  -0.176  -0.166  -0.333  -0.365  -0.357  -0.493
162   K        -0.329  -0.343  -0.429  -0.292  -0.307  -0.439  -0.365  -0.383  -0.494
163   L         0.587   0.567   0.434   0.428   0.394   0.183   0.541   0.509   0.271
164   D         0.235   0.239   0.290   0.076   0.087   0.156  -0.063  -0.056   0.013
165   E        -1.107  -1.112  -1.099  -0.991  -0.995  -0.971  -0.968  -0.973  -0.933
166   F        -0.329  -0.321  -0.439  -0.255  -0.244  -0.432  -0.365  -0.353  -0.507
167   A        -0.543  -0.552  -0.524  -0.628  -0.645  -0.587  -0.667  -0.676  -0.622
168   K        -0.329  -0.319  -0.435  -0.246  -0.224  -0.406  -0.365  -0.351  -0.502
169   R        -0.543  -0.538  -0.507  -0.602  -0.591  -0.526  -0.667  -0.661  -0.602
170   A         0.235   0.239   0.290   0.135   0.142   0.215  -0.063  -0.056   0.013
171   K        -1.672  -1.670  -1.584  -1.540  -1.532  -1.405  -1.270  -1.268  -1.154
172   D        -0.543  -0.552  -0.524  -0.642  -0.654  -0.595  -0.667  -0.676  -0.622
173   Y         0.587   0.567   0.434   0.775   0.745   0.544   0.541   0.509   0.271
174   K         0.235   0.239   0.290   0.062   0.071   0.150  -0.063  -0.056   0.013
175   D         0.235   0.239   0.290   0.116   0.127   0.198  -0.063  -0.056   0.013
176   P         0.310   0.288   0.304   0.317   0.276   0.283   0.071   0.032   0.039
177   L        -0.329  -0.321  -0.439  -0.417  -0.409  -0.568  -0.365  -0.353  -0.507
178   Y         0.235   0.239   0.290   0.186   0.192   0.267  -0.063  -0.056   0.013
179   G        -0.329  -0.321  -0.439  -0.144  -0.130  -0.340  -0.365  -0.353  -0.507
180   S        -0.543  -0.538  -0.512  -0.774  -0.772  -0.712  -0.667  -0.661  -0.608
181   K        -0.329  -0.319  -0.435  -0.311  -0.291  -0.505  -0.365  -0.351  -0.502
182   I         0.235   0.226   0.277  -0.139  -0.164  -0.088  -0.063  -0.080  -0.011
183   R         0.587   0.591   0.444   0.637   0.648   0.406   0.541   0.546   0.289
184   I         0.587   0.567   0.434   0.547   0.516   0.315   0.541   0.509   0.271
185   V         0.235   0.239   0.290   0.013   0.018   0.094  -0.063  -0.056   0.013
186   G         1.606   1.607   1.661   1.753   1.754   1.840   1.748   1.750   1.829
187   D         0.235   0.239   0.290   0.143   0.152   0.226  -0.063  -0.056   0.013
188   Q        -0.329  -0.323  -0.429  -0.263  -0.255  -0.429  -0.365  -0.357  -0.493
189   S         0.587   0.591   0.444   0.556   0.558   0.342   0.541   0.546   0.289
190   L        -0.329  -0.321  -0.439  -0.404  -0.395  -0.550  -0.365  -0.353  -0.507
191   L         0.235   0.238   0.281  -0.139  -0.138  -0.078  -0.063  -0.059  -0.004
192   S         0.235   0.239   0.290   0.040   0.043   0.129  -0.063  -0.056   0.013
193   P        -0.543  -0.540  -0.511  -0.608  -0.606  -0.564  -0.667  -0.664  -0.606
194   E         0.235   0.239   0.290   0.082   0.091   0.167  -0.063  -0.056   0.013
195   M        -0.543  -0.527  -0.518  -0.793  -0.783  -0.725  -0.667  -0.650  -0.614
196   R         0.235   0.240   0.284  -0.100  -0.094  -0.019  -0.063  -0.055   0.003
197   K         0.587   0.573   0.439   0.578   0.562   0.348   0.541   0.518   0.279
198   K        -0.543  -0.549  -0.519  -0.637  -0.641  -0.595  -0.667  -0.673  -0.616
199   I         0.235   0.239   0.290  -0.139  -0.136  -0.057  -0.063  -0.056   0.013
200   K        -0.329  -0.323  -0.429  -0.301  -0.287  -0.471  -0.365  -0.357  -0.493
201   K        -0.329  -0.305  -0.411  -0.218  -0.176  -0.358  -0.365  -0.331  -0.469
202   V        -0.329  -0.343  -0.429  -0.259  -0.282  -0.427  -0.365  -0.383  -0.494
203   E         1.606   1.607   1.661   1.602   1.606   1.690   1.748   1.750   1.829
204   E         0.235   0.226   0.277   0.011  -0.004   0.066  -0.063  -0.080  -0.011
205   I        -1.107  -1.087  -1.088  -1.254  -1.226  -1.215  -0.968  -0.946  -0.922
206   T         1.606   1.607   1.661   1.636   1.636   1.724   1.748   1.750   1.829
207   Q        -1.107  -1.110  -1.107  -1.037  -1.040  -1.022  -0.968  -0.972  -0.942
208   D        -0.329  -0.338  -0.421  -0.132  -0.144  -0.263  -0.365  -0.377  -0.482
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   G         0.235   0.233   0.275   0.125   0.115   0.165  -0.063  -0.068  -0.014
211   D        -1.107  -1.110  -1.107  -1.041  -1.045  -1.019  -0.968  -0.972  -0.942
212   D        -1.107  -1.102  -1.076  -1.053  -1.043  -0.998  -0.968  -0.962  -0.909
213   F         0.235   0.239   0.290   0.023   0.032   0.105  -0.063  -0.056   0.013
214   T        -0.543  -0.549  -0.506  -0.651  -0.664  -0.595  -0.667  -0.673  -0.602
215   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
216   F        -0.543  -0.527  -0.518  -0.522  -0.500  -0.479  -0.667  -0.650  -0.614
217   I        -0.543  -0.552  -0.524  -0.770  -0.790  -0.753  -0.667  -0.676  -0.622
218   C         0.587   0.567   0.434   0.913   0.884   0.673   0.541   0.509   0.271
219   F         0.587   0.567   0.434   0.596   0.563   0.328   0.541   0.509   0.271
220   P         1.606   1.607   1.661   1.720   1.721   1.807   1.748   1.750   1.829
221   Y         1.606   1.607   1.661   1.727   1.727   1.813   1.748   1.750   1.829
222   T         1.606   1.607   1.661   1.636   1.636   1.724   1.748   1.750   1.829
223   S         0.587   0.595   0.444   0.575   0.584   0.372   0.541   0.554   0.288
224   R         1.606   1.607   1.661   1.626   1.632   1.714   1.748   1.750   1.829
225   N         0.235   0.239   0.290   0.142   0.151   0.226  -0.063  -0.056   0.013
226   D         0.587   0.595   0.444   0.699   0.713   0.471   0.541   0.554   0.288
227   M         0.587   0.615   0.446   0.582   0.618   0.390   0.541   0.586   0.293
228   L        -1.672  -1.670  -1.584  -1.602  -1.598  -1.467  -1.270  -1.268  -1.154
229   H        -0.329  -0.335  -0.421   0.010   0.005  -0.131  -0.365  -0.372  -0.482
230   T        -0.543  -0.538  -0.512  -0.656  -0.655  -0.594  -0.667  -0.661  -0.608
231   I        -0.329  -0.357  -0.437  -0.313  -0.356  -0.463  -0.365  -0.402  -0.503
232   R        -1.107  -1.096  -1.081  -0.923  -0.901  -0.902  -0.968  -0.956  -0.914
233   D        -1.672  -1.670  -1.584  -1.604  -1.604  -1.469  -1.270  -1.268  -1.154
234   S        -1.107  -1.110  -1.107  -1.171  -1.179  -1.169  -0.968  -0.972  -0.942
235   V        -0.543  -0.527  -0.518  -0.552  -0.535  -0.511  -0.667  -0.650  -0.614
236   E        -0.543  -0.537  -0.508  -0.639  -0.628  -0.587  -0.667  -0.660  -0.604
237   D         0.587   0.615   0.446   0.597   0.640   0.390   0.541   0.586   0.293
238   H        -1.672  -1.670  -1.584  -1.278  -1.273  -1.148  -1.270  -1.268  -1.154
239   L        -1.107  -1.102  -1.076  -1.179  -1.170  -1.147  -0.968  -0.962  -0.909
240   E        -1.107  -1.110  -1.107  -1.043  -1.045  -1.020  -0.968  -0.972  -0.942
241   N        -1.107  -1.087  -1.088  -1.083  -1.055  -1.042  -0.968  -0.946  -0.922
242   K        -0.512  -0.532  -0.524  -0.601  -0.632  -0.634  -0.610  -0.638  -0.618
243   -         0.310   0.354   0.329  -0.015   0.067   0.005   0.071   0.149   0.084
244   -        -0.632  -0.618  -0.554  -0.860  -0.851  -0.736  -0.767  -0.750  -0.657
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   S        -1.107  -1.096  -1.081  -1.023  -1.001  -0.992  -0.968  -0.956  -0.914
247   P        -1.672  -1.670  -1.584  -1.449  -1.451  -1.316  -1.270  -1.268  -1.154
248   R        -1.672  -1.670  -1.584  -1.432  -1.422  -1.299  -1.270  -1.268  -1.154
249   I         0.587   0.573   0.439   0.496   0.471   0.242   0.541   0.518   0.279
250   N        -0.329  -0.319  -0.435  -0.264  -0.252  -0.445  -0.365  -0.351  -0.502
251   I        -1.107  -1.112  -1.099  -1.225  -1.236  -1.219  -0.968  -0.973  -0.933
252   R        -1.672  -1.670  -1.584  -1.481  -1.468  -1.348  -1.270  -1.268  -1.154
253   K        -1.107  -1.110  -1.107  -1.036  -1.040  -1.043  -0.968  -0.972  -0.942
254   F        -0.543  -0.538  -0.512  -0.814  -0.813  -0.767  -0.667  -0.661  -0.608
255   T         0.587   0.595   0.444   0.659   0.670   0.434   0.541   0.554   0.288
256   N        -0.543  -0.552  -0.504  -0.621  -0.630  -0.551  -0.667  -0.676  -0.599
257   K        -0.329  -0.319  -0.435  -0.266  -0.248  -0.464  -0.365  -0.351  -0.502
258   M         0.587   0.595   0.444   0.791   0.802   0.560   0.541   0.554   0.288
259   Y         0.587   0.573   0.439   0.802   0.782   0.593   0.541   0.518   0.279
260   M         0.235   0.245   0.280   0.145   0.160   0.218  -0.063  -0.045  -0.004
261   G        -0.329  -0.357  -0.437  -0.166  -0.210  -0.364  -0.365  -0.402  -0.503
262   F        -1.672  -1.670  -1.584  -1.402  -1.396  -1.270  -1.270  -1.268  -1.154
263   H        -1.107  -1.087  -1.088  -0.842  -0.813  -0.811  -0.968  -0.946  -0.922
264   S        -0.329  -0.321  -0.439  -0.350  -0.340  -0.519  -0.365  -0.353  -0.507
265   N        -0.543  -0.549  -0.519  -0.506  -0.514  -0.463  -0.667  -0.673  -0.616
266   K        -0.543  -0.549  -0.519  -0.589  -0.595  -0.546  -0.667  -0.673  -0.616
267   C         0.235   0.239   0.290   0.172   0.179   0.243  -0.063  -0.056   0.013
268   E         0.587   0.615   0.446   0.699   0.742   0.476   0.541   0.586   0.293
269   L         0.235   0.238   0.281  -0.139  -0.138  -0.078  -0.063  -0.059  -0.004
270   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
271   I         1.606   1.607   1.661   1.516   1.515   1.605   1.748   1.750   1.829
272   R         1.606   1.607   1.661   1.626   1.632   1.714   1.748   1.750   1.829
273   T         1.606   1.607   1.661   1.636   1.636   1.724   1.748   1.750   1.829
274   S         1.606   1.607   1.661   1.522   1.522   1.612   1.748   1.750   1.829
275   G         1.606   1.607   1.661   1.753   1.754   1.840   1.748   1.750   1.829
276   H         1.606   1.607   1.661   1.822   1.828   1.908   1.748   1.750   1.829
277   R        -0.329  -0.319  -0.435  -0.269  -0.253  -0.452  -0.365  -0.351  -0.502
278   R         1.606   1.607   1.661   1.626   1.632   1.714   1.748   1.750   1.829
279   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
280   S         1.606   1.607   1.661   1.522   1.522   1.612   1.748   1.750   1.829
281   D         1.606   1.607   1.661   1.676   1.680   1.764   1.748   1.750   1.829
282   Y         0.235   0.238   0.281   0.122   0.125   0.193  -0.063  -0.059  -0.004
283   M         0.587   0.595   0.444   0.746   0.757   0.490   0.541   0.554   0.288
284   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
285   W         1.606   1.607   1.661   1.868   1.870   1.953   1.748   1.750   1.829
286   Q         1.606   1.607   1.661   1.799   1.803   1.885   1.748   1.750   1.829
287   V         0.235   0.239   0.290   0.215   0.219   0.304  -0.063  -0.056   0.013
288   H        -0.543  -0.538  -0.507  -0.448  -0.440  -0.395  -0.667  -0.661  -0.602
289   E        -0.329  -0.321  -0.439  -0.243  -0.230  -0.410  -0.365  -0.353  -0.507
290   N        -1.107  -1.120  -1.080  -0.881  -0.895  -0.834  -0.968  -0.982  -0.913
291   A        -0.543  -0.552  -0.524  -0.427  -0.445  -0.415  -0.667  -0.676  -0.622
292   T        -0.329  -0.343  -0.429  -0.236  -0.261  -0.398  -0.365  -0.383  -0.494
293   I         0.587   0.573   0.439   0.582   0.561   0.378   0.541   0.518   0.279
294   E         1.606   1.607   1.661   1.602   1.606   1.690   1.748   1.750   1.829
295   F         1.606   1.607   1.661   1.615   1.617   1.704   1.748   1.750   1.829
296   S        -0.543  -0.538  -0.512  -0.659  -0.655  -0.589  -0.667  -0.661  -0.608
297   D         0.587   0.573   0.439   0.707   0.688   0.475   0.541   0.518   0.279
298   T        -1.107  -1.120  -1.080  -0.972  -0.994  -0.928  -0.968  -0.982  -0.913
299   L         1.606   1.607   1.661   1.424   1.423   1.516   1.748   1.750   1.829
300   W         1.606   1.607   1.661   1.868   1.870   1.953   1.748   1.750   1.829
301   P         1.606   1.607   1.661   1.720   1.721   1.807   1.748   1.750   1.829
302   N        -1.107  -1.099  -1.079  -0.919  -0.902  -0.875  -0.968  -0.959  -0.912
303   F         1.606   1.607   1.661   1.615   1.617   1.704   1.748   1.750   1.829
304   S        -1.107  -1.087  -1.088  -0.991  -0.956  -0.969  -0.968  -0.946  -0.922
305   F         0.587   0.591   0.444   0.619   0.624   0.385   0.541   0.546   0.289
306   F        -0.543  -0.538  -0.512  -0.495  -0.487  -0.447  -0.667  -0.661  -0.608
307   A        -1.672  -1.670  -1.584  -1.439  -1.434  -1.306  -1.270  -1.268  -1.154
308   M        -0.543  -0.552  -0.524  -0.668  -0.688  -0.649  -0.667  -0.676  -0.622
309   Y         0.235   0.239   0.290   0.238   0.243   0.322  -0.063  -0.056   0.013
310   L        -0.543  -0.552  -0.524  -0.749  -0.762  -0.675  -0.667  -0.676  -0.622
311   M         0.587   0.615   0.446   0.582   0.618   0.390   0.541   0.586   0.293
312   I        -0.329  -0.339  -0.426  -0.378  -0.395  -0.534  -0.365  -0.378  -0.490
313   L        -0.329  -0.321  -0.439  -0.488  -0.479  -0.665  -0.365  -0.353  -0.507
314   K         0.587   0.573   0.439   0.584   0.568   0.357   0.541   0.518   0.279
315   W         1.606   1.607   1.661   1.868   1.870   1.953   1.748   1.750   1.829
316   S         1.606   1.607   1.661   1.522   1.522   1.612   1.748   1.750   1.829
317   F        -0.543  -0.549  -0.519  -0.509  -0.519  -0.458  -0.667  -0.673  -0.616
318   F         0.235   0.240   0.284   0.154   0.160   0.222  -0.063  -0.055   0.003
319   S        -1.107  -1.110  -1.107  -1.040  -1.037  -1.045  -0.968  -0.972  -0.942
320   T         0.587   0.573   0.439   0.700   0.678   0.489   0.541   0.518   0.279
321   I        -1.107  -1.123  -1.081  -1.116  -1.138  -1.069  -0.968  -0.984  -0.915
322   Q         1.606   1.607   1.661   1.799   1.803   1.885   1.748   1.750   1.829
323   K        -1.107  -1.102  -1.076  -1.230  -1.220  -1.185  -0.968  -0.962  -0.909
324   Y        -0.543  -0.552  -0.524  -0.537  -0.550  -0.492  -0.667  -0.676  -0.622
325   N        -1.107  -1.112  -1.099  -0.982  -0.990  -0.976  -0.968  -0.973  -0.933
326   E        -0.543  -0.549  -0.506  -0.468  -0.470  -0.399  -0.667  -0.673  -0.602
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   K        -1.672  -1.670  -1.584  -1.508  -1.501  -1.375  -1.270  -1.268  -1.154
334   N        -0.543  -0.552  -0.524  -0.666  -0.678  -0.624  -0.667  -0.676  -0.622
335   H        -1.672  -1.670  -1.584  -1.370  -1.371  -1.238  -1.270  -1.268  -1.154
336   S        -0.329  -0.339  -0.426  -0.312  -0.329  -0.449  -0.365  -0.378  -0.490
337   L        -1.107  -1.102  -1.076  -1.164  -1.150  -1.119  -0.968  -0.962  -0.909
338   F        -1.107  -1.109  -1.090  -1.007  -1.004  -0.979  -0.968  -0.970  -0.924
339   E        -1.107  -1.099  -1.079  -1.044  -1.030  -1.019  -0.968  -0.959  -0.912
340   K         0.235   0.239   0.290   0.011   0.024   0.097  -0.063  -0.056   0.013
341   I        -1.107  -1.109  -1.090  -1.146  -1.151  -1.115  -0.968  -0.970  -0.924
342   H        -1.672  -1.670  -1.584  -1.323  -1.327  -1.192  -1.270  -1.268  -1.154
343   E        -1.107  -1.123  -1.081  -0.978  -1.001  -0.931  -0.968  -0.984  -0.915
344   S        -1.107  -1.099  -1.075  -1.106  -1.090  -1.055  -0.968  -0.960  -0.909
345   V        -1.107  -1.087  -1.088  -1.218  -1.194  -1.174  -0.968  -0.946  -0.922
346   P        -0.329  -0.338  -0.421  -0.094  -0.108  -0.228  -0.365  -0.377  -0.482
347   S        -0.632  -0.629  -0.554  -0.911  -0.902  -0.786  -0.767  -0.764  -0.657
348   I        -0.632  -0.629  -0.554  -0.713  -0.708  -0.591  -0.767  -0.764  -0.657
349   F        -0.632  -0.629  -0.554  -0.686  -0.681  -0.565  -0.767  -0.764  -0.657
350   K         0.310   0.288   0.304   0.037  -0.007  -0.010   0.071   0.032   0.039
351   K         0.310   0.315   0.313   0.165   0.176   0.163   0.071   0.080   0.056
352   K        -0.632  -0.629  -0.554  -0.837  -0.830  -0.713  -0.767  -0.764  -0.657
353   K        -0.632  -0.629  -0.554  -0.921  -0.913  -0.796  -0.767  -0.764  -0.657
354   T         0.310   0.331   0.316   0.165   0.204   0.168   0.071   0.110   0.061
355   A        -1.672  -1.670  -1.584  -1.399  -1.399  -1.267  -1.270  -1.268  -1.154
356   M        -1.107  -1.099  -1.079  -1.004  -0.997  -0.960  -0.968  -0.959  -0.912
357   S        -1.672  -1.670  -1.584  -1.725  -1.723  -1.588  -1.270  -1.268  -1.154
358   L         0.587   0.573   0.439   0.429   0.404   0.194   0.541   0.518   0.279
359   Y        -1.107  -1.110  -1.107  -1.047  -1.050  -1.034  -0.968  -0.972  -0.942
360   N        -1.107  -1.110  -1.107  -1.084  -1.089  -1.090  -0.968  -0.972  -0.942
361   F         0.587   0.615   0.446   0.453   0.490   0.245   0.541   0.586   0.293
362   P         1.606   1.607   1.661   1.720   1.721   1.807   1.748   1.750   1.829
363   N        -1.107  -1.123  -1.081  -0.909  -0.931  -0.867  -0.968  -0.984  -0.915
364   P        -0.329  -0.343  -0.429  -0.080  -0.101  -0.224  -0.365  -0.383  -0.494
365   P         1.606   1.607   1.661   1.720   1.721   1.807   1.748   1.750   1.829
366   I        -1.107  -1.110  -1.107  -1.030  -1.040  -1.060  -0.968  -0.972  -0.942
367   S        -0.329  -0.305  -0.411  -0.209  -0.171  -0.360  -0.365  -0.331  -0.469
368   V        -0.329  -0.321  -0.439  -0.222  -0.211  -0.393  -0.365  -0.353  -0.507
369   S         0.587   0.573   0.439   0.577   0.555   0.366   0.541   0.518   0.279
370   V         0.587   0.591   0.444   0.631   0.635   0.395   0.541   0.546   0.289
371   T        -0.329  -0.339  -0.426  -0.265  -0.281  -0.431  -0.365  -0.378  -0.490
372   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   D        -1.218  -1.207  -1.134  -1.092  -1.071  -0.964  -1.082  -1.071  -0.968
374   E        -1.218  -1.207  -1.134  -1.154  -1.122  -1.025  -1.082  -1.071  -0.968
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03175
Output conservation file - output/Q03175
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
