1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    M         0.563   0.418   0.344   0.838   0.624   0.465   0.545   0.308   0.151
24    P        -0.428  -0.522  -0.453  -0.444  -0.585  -0.491  -0.593  -0.699  -0.611
25    I        -0.516  -0.558  -0.460  -0.692  -0.720  -0.569  -0.736  -0.753  -0.619
26    K        -0.428  -0.395  -0.454  -0.581  -0.567  -0.627  -0.593  -0.586  -0.612
27    E        -0.138  -0.352  -0.403  -0.086  -0.378  -0.471  -0.166  -0.458  -0.536
28    T        -0.138  -0.225  -0.373  -0.111  -0.249  -0.492  -0.166  -0.292  -0.496
29    D        -0.516  -0.569  -0.459  -0.692  -0.728  -0.568  -0.736  -0.770  -0.621
30    K        -1.011  -0.839  -0.931  -1.099  -0.840  -0.971  -1.020  -0.812  -0.879
31    E        -1.011  -0.983  -0.955  -0.976  -0.925  -0.861  -1.020  -0.983  -0.906
32    V         0.563   0.669   0.374   0.525   0.660   0.268   0.545   0.701   0.204
33    V        -0.651  -0.589  -0.497  -0.903  -0.809  -0.670  -0.878  -0.793  -0.664
34    L        -1.011  -1.089  -0.963  -1.160  -1.244  -1.061  -1.020  -1.070  -0.913
35    T         1.308   1.334   1.388   1.242   1.265   1.373   1.399   1.432   1.512
36    H        -1.011  -1.024  -0.968  -0.952  -0.994  -0.933  -1.020  -1.017  -0.918
37    P         1.308   1.334   1.388   1.333   1.376   1.458   1.399   1.432   1.512
38    A        -0.948  -0.908  -0.952  -0.855  -0.846  -0.894  -0.926  -0.887  -0.898
39    D        -0.529  -0.579  -0.467  -0.625  -0.698  -0.530  -0.732  -0.771  -0.626
40    E        -1.011  -1.021  -0.955  -1.087  -1.112  -0.998  -1.020  -1.013  -0.906
41    T        -0.651  -0.520  -0.484  -0.857  -0.645  -0.597  -0.878  -0.691  -0.647
42    T        -0.268  -0.380  -0.437  -0.233  -0.420  -0.505  -0.344  -0.506  -0.583
43    S        -1.107  -1.110  -0.986  -1.193  -1.204  -0.991  -1.119  -1.096  -0.935
44    V         0.221   0.316   0.249   0.033   0.172   0.073  -0.024   0.134  -0.023
45    H        -1.371  -1.376  -1.345  -1.209  -1.273  -1.154  -1.163  -1.158  -1.079
46    I         0.563   0.418   0.344   0.646   0.449   0.294   0.545   0.308   0.151
47    L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
48    K        -0.138  -0.352  -0.403  -0.083  -0.379  -0.474  -0.166  -0.458  -0.536
49    Y         0.563   0.632   0.369   0.811   0.902   0.526   0.545   0.645   0.196
50    G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
51    A         1.308   1.334   1.388   1.363   1.380   1.486   1.399   1.432   1.512
52    T         1.308   1.334   1.388   1.242   1.265   1.373   1.399   1.432   1.512
53    V         0.563   0.633   0.370   0.525   0.617   0.261   0.545   0.648   0.197
54    Y        -1.866  -1.706  -1.674  -1.805  -1.599  -1.518  -1.447  -1.290  -1.205
55    S         1.308   1.334   1.388   1.284   1.308   1.412   1.399   1.432   1.512
56    W         1.308   1.334   1.388   1.470   1.503   1.585   1.399   1.432   1.512
57    K        -0.428  -0.430  -0.426  -0.600  -0.570  -0.601  -0.593  -0.572  -0.573
58    L        -1.011  -1.102  -0.979  -1.122  -1.202  -1.030  -1.020  -1.085  -0.929
59    K        -0.428  -0.415  -0.425  -0.524  -0.470  -0.508  -0.593  -0.550  -0.573
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    S        -0.138   0.026  -0.334  -0.037   0.180  -0.329  -0.166   0.057  -0.442
62    E        -1.371  -1.431  -1.368  -1.249  -1.305  -1.225  -1.163  -1.204  -1.099
63    E         1.308   1.334   1.388   1.224   1.275   1.356   1.399   1.432   1.512
64    Q         0.068   0.091   0.191  -0.138  -0.101   0.039  -0.309  -0.276  -0.132
65    L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
66    W         1.308   1.334   1.388   1.470   1.503   1.585   1.399   1.432   1.512
67    L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
68    S         1.308   1.334   1.388   1.284   1.308   1.412   1.399   1.432   1.512
69    T        -0.516  -0.416  -0.444  -0.775  -0.601  -0.634  -0.736  -0.591  -0.598
70    A        -0.138  -0.172  -0.363   0.030  -0.043  -0.333  -0.166  -0.214  -0.481
71    A         1.308   1.334   1.388   1.363   1.380   1.486   1.399   1.432   1.512
72    K         0.563   0.632   0.369   0.594   0.696   0.351   0.545   0.645   0.196
73    L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
74    D         1.308   1.334   1.388   1.314   1.347   1.440   1.399   1.432   1.512
75    G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
76    S         1.308   1.334   1.388   1.284   1.308   1.412   1.399   1.432   1.512
77    K         1.308   1.334   1.388   1.232   1.280   1.363   1.399   1.432   1.512
78    P         0.221   0.214   0.227   0.178   0.156   0.158  -0.024  -0.048  -0.063
79    V         1.308   1.334   1.388   1.189   1.219   1.323   1.399   1.432   1.512
80    R         1.308   1.334   1.388   1.501   1.529   1.614   1.399   1.432   1.512
81    G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
82    G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
83    I         0.563   0.633   0.370   0.646   0.757   0.342   0.545   0.648   0.197
84    P         1.308   1.334   1.388   1.341   1.382   1.465   1.399   1.432   1.512
85    L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
86    V         1.308   1.334   1.388   1.189   1.219   1.323   1.399   1.432   1.512
87    F         1.308   1.334   1.388   1.393   1.432   1.513   1.399   1.432   1.512
88    P         1.308   1.334   1.388   1.341   1.382   1.465   1.399   1.432   1.512
89    V         0.563   0.633   0.370   0.566   0.652   0.346   0.545   0.648   0.197
90    F         1.308   1.334   1.388   1.393   1.432   1.513   1.399   1.432   1.512
91    G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
92    K         0.563   0.418   0.344   0.552   0.356   0.223   0.545   0.308   0.151
93    N        -1.371  -1.431  -1.368  -1.080  -1.190  -1.071  -1.163  -1.204  -1.099
94    S        -2.226  -2.114  -1.974  -1.961  -1.813  -1.611  -1.590  -1.478  -1.307
95    T        -0.787  -0.665  -0.882  -0.682  -0.521  -0.866  -0.736  -0.592  -0.821
96    D        -0.948  -1.013  -0.979  -0.869  -0.956  -0.936  -0.926  -0.995  -0.926
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    E        -1.371  -1.431  -1.368  -1.232  -1.318  -1.201  -1.163  -1.204  -1.099
99    H        -1.011  -0.949  -0.949  -0.916  -0.800  -0.838  -1.020  -0.932  -0.897
100   L        -0.516  -0.416  -0.444  -0.798  -0.623  -0.623  -0.736  -0.591  -0.598
101   S        -0.787  -0.818  -0.920  -0.628  -0.701  -0.822  -0.736  -0.770  -0.863
102   K        -0.138  -0.352  -0.403  -0.078  -0.377  -0.465  -0.166  -0.458  -0.536
103   L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
104   P         1.308   1.334   1.388   1.341   1.382   1.465   1.399   1.432   1.512
105   Q         1.308   1.334   1.388   1.393   1.435   1.513   1.399   1.432   1.512
106   H         1.308   1.334   1.388   1.484   1.523   1.598   1.399   1.432   1.512
107   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
108   L         0.221   0.353   0.278   0.146   0.386   0.200  -0.024   0.199   0.031
109   A         1.308   1.334   1.388   1.363   1.380   1.486   1.399   1.432   1.512
110   R         1.308   1.334   1.388   1.501   1.529   1.614   1.399   1.432   1.512
111   N        -0.138  -0.352  -0.403   0.010  -0.312  -0.429  -0.166  -0.458  -0.536
112   S         1.308   1.334   1.388   1.284   1.308   1.412   1.399   1.432   1.512
113   T        -0.138  -0.192  -0.366  -0.065  -0.144  -0.392  -0.166  -0.251  -0.485
114   W         1.308   1.334   1.388   1.470   1.503   1.585   1.399   1.432   1.512
115   E         1.308   1.334   1.388   1.224   1.275   1.356   1.399   1.432   1.512
116   F         0.563   0.478   0.355   0.750   0.650   0.463   0.545   0.407   0.170
117   L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
118   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
119   Q         0.563   0.418   0.344   0.711   0.514   0.362   0.545   0.308   0.151
120   T        -0.428  -0.444  -0.420  -0.597  -0.609  -0.580  -0.593  -0.586  -0.563
121   K        -1.011  -1.024  -0.968  -1.106  -1.133  -1.015  -1.020  -1.017  -0.918
122   E         0.068   0.102   0.195  -0.246  -0.187  -0.037  -0.309  -0.256  -0.124
123   N        -1.011  -1.102  -0.979  -1.043  -1.183  -1.023  -1.020  -1.085  -0.929
124   P         0.563   0.418   0.344   0.669   0.468   0.335   0.545   0.308   0.151
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   P        -1.011  -1.024  -0.968  -1.037  -1.077  -0.975  -1.020  -1.017  -0.918
154   T        -0.138  -0.352  -0.403  -0.085  -0.413  -0.490  -0.166  -0.458  -0.536
155   V        -0.516  -0.563  -0.452  -0.753  -0.788  -0.635  -0.736  -0.760  -0.611
156   Q         0.563   0.418   0.344   0.725   0.530   0.391   0.545   0.308   0.151
157   F         0.563   0.669   0.374   0.698   0.848   0.389   0.545   0.701   0.204
158   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
159   L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
160   K        -0.787  -0.712  -0.892  -0.685  -0.603  -0.867  -0.736  -0.655  -0.833
161   P         0.563   0.418   0.344   0.669   0.468   0.335   0.545   0.308   0.151
162   E        -0.138  -0.159  -0.359  -0.118  -0.149  -0.463  -0.166  -0.211  -0.477
163   I        -1.506  -1.448  -1.366  -1.372  -1.277  -1.158  -1.305  -1.225  -1.098
164   A        -0.651  -0.618  -0.508  -0.928  -0.914  -0.739  -0.878  -0.825  -0.678
165   N        -0.651  -0.618  -0.508  -0.803  -0.766  -0.596  -0.878  -0.825  -0.678
166   P        -1.147  -1.119  -0.982  -1.210  -1.152  -0.960  -1.163  -1.102  -0.932
167   E         0.221   0.184   0.215   0.048  -0.012   0.016  -0.024  -0.103  -0.087
168   L        -0.428  -0.441  -0.462  -0.612  -0.637  -0.640  -0.593  -0.632  -0.622
169   T        -1.866  -1.821  -1.698  -1.780  -1.677  -1.531  -1.447  -1.383  -1.223
170   K        -0.138  -0.192  -0.366  -0.071  -0.145  -0.393  -0.166  -0.251  -0.485
171   L        -0.138  -0.352  -0.403  -0.172  -0.455  -0.554  -0.166  -0.458  -0.536
172   W         1.308   1.334   1.388   1.470   1.503   1.585   1.399   1.432   1.512
173   P        -0.428  -0.445  -0.438  -0.425  -0.427  -0.443  -0.593  -0.594  -0.588
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   M        -0.787  -0.508  -0.876  -0.459  -0.069  -0.623  -0.736  -0.393  -0.815
178   D        -0.787  -0.899  -0.929  -0.636  -0.809  -0.875  -0.736  -0.865  -0.874
179   Y         0.221   0.353   0.278   0.265   0.473   0.338  -0.024   0.199   0.031
180   L        -1.011  -0.872  -0.944  -1.104  -0.908  -1.004  -1.020  -0.870  -0.895
181   L         0.563   0.418   0.344   0.489   0.311   0.194   0.545   0.308   0.151
182   I         0.563   0.669   0.374   0.646   0.803   0.349   0.545   0.701   0.204
183   L         0.221   0.132   0.207   0.036  -0.079   0.036  -0.024  -0.199  -0.102
184   T         0.068   0.094   0.191  -0.231  -0.210  -0.031  -0.309  -0.271  -0.131
185   V         0.221   0.338   0.255   0.022   0.208   0.068  -0.024   0.172  -0.011
186   E        -0.516  -0.417  -0.445  -0.762  -0.599  -0.612  -0.736  -0.593  -0.599
187   L         0.563   0.478   0.355   0.484   0.398   0.200   0.545   0.407   0.170
188   G        -0.787  -0.925  -0.941  -0.675  -0.890  -0.930  -0.736  -0.892  -0.886
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   S        -1.866  -1.813  -1.689  -1.845  -1.762  -1.586  -1.447  -1.378  -1.216
192   D        -0.138  -0.138  -0.353  -0.041  -0.045  -0.396  -0.166  -0.172  -0.468
193   Y        -1.866  -1.821  -1.698  -1.572  -1.559  -1.368  -1.447  -1.383  -1.223
194   L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
195   K        -0.787  -0.925  -0.941  -0.787  -1.011  -1.075  -0.736  -0.892  -0.886
196   T         1.308   1.334   1.388   1.242   1.265   1.373   1.399   1.432   1.512
197   A        -1.506  -1.427  -1.360  -1.371  -1.233  -1.156  -1.305  -1.205  -1.093
198   I        -0.138  -0.352  -0.403   0.023  -0.269  -0.381  -0.166  -0.458  -0.536
199   E        -0.787  -0.925  -0.941  -0.761  -0.989  -1.024  -0.736  -0.892  -0.886
200   V         0.563   0.418   0.344   0.525   0.328   0.219   0.545   0.308   0.151
201   E        -0.138  -0.192  -0.366  -0.144  -0.219  -0.521  -0.166  -0.251  -0.485
202   N         1.308   1.334   1.388   1.351   1.395   1.475   1.399   1.432   1.512
203   T        -0.428  -0.522  -0.453  -0.509  -0.661  -0.534  -0.593  -0.699  -0.611
204   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   S        -1.506  -1.505  -1.376  -1.492  -1.478  -1.286  -1.305  -1.272  -1.106
206   S        -1.866  -1.744  -1.676  -1.845  -1.639  -1.568  -1.447  -1.321  -1.207
207   K        -1.011  -0.982  -0.940  -1.053  -0.957  -0.903  -1.020  -0.966  -0.889
208   E        -1.866  -1.825  -1.698  -1.702  -1.651  -1.478  -1.447  -1.386  -1.223
209   L        -1.011  -0.949  -0.949  -0.931  -0.797  -0.794  -1.020  -0.932  -0.897
210   K        -0.428  -0.518  -0.460  -0.583  -0.712  -0.637  -0.593  -0.704  -0.621
211   F         0.563   0.418   0.344   0.767   0.593   0.484   0.545   0.308   0.151
212   N         0.563   0.418   0.344   0.696   0.514   0.383   0.545   0.308   0.151
213   W        -0.138  -0.352  -0.403   0.190  -0.098  -0.206  -0.166  -0.458  -0.536
214   L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
215   F         0.563   0.418   0.344   0.760   0.582   0.468   0.545   0.308   0.151
216   H         1.308   1.334   1.388   1.484   1.523   1.598   1.399   1.432   1.512
217   T         1.308   1.334   1.388   1.242   1.265   1.373   1.399   1.432   1.512
218   Y         1.308   1.334   1.388   1.467   1.501   1.583   1.399   1.432   1.512
219   F        -0.428  -0.297  -0.418  -0.544  -0.331  -0.484  -0.593  -0.402  -0.562
220   R        -0.428  -0.247  -0.405  -0.296  -0.025  -0.267  -0.593  -0.348  -0.546
221   I         0.221   0.132   0.207   0.105  -0.079   0.013  -0.024  -0.199  -0.102
222   E        -1.506  -1.449  -1.363  -1.423  -1.302  -1.181  -1.305  -1.226  -1.096
223   D         0.563   0.478   0.355   0.632   0.516   0.309   0.545   0.407   0.170
224   I         1.308   1.334   1.388   1.334   1.385   1.458   1.399   1.432   1.512
225   E        -0.516  -0.522  -0.454  -0.742  -0.722  -0.597  -0.736  -0.710  -0.612
226   G        -0.787  -0.879  -0.927  -0.642  -0.801  -0.880  -0.736  -0.845  -0.872
227   T        -0.428  -0.440  -0.460  -0.586  -0.665  -0.642  -0.593  -0.631  -0.620
228   M        -1.506  -1.518  -1.370  -1.449  -1.474  -1.271  -1.305  -1.281  -1.102
229   V         0.563   0.418   0.344   0.525   0.328   0.219   0.545   0.308   0.151
230   S        -1.011  -1.045  -0.972  -1.016  -1.060  -0.924  -1.020  -1.038  -0.922
231   N         0.221   0.132   0.207   0.156  -0.019   0.080  -0.024  -0.199  -0.102
232   L         0.563   0.633   0.370   0.494   0.608   0.246   0.545   0.648   0.197
233   A        -2.226  -2.114  -1.974  -2.103  -1.929  -1.743  -1.590  -1.478  -1.307
234   G        -1.506  -1.505  -1.376  -1.454  -1.441  -1.248  -1.305  -1.272  -1.106
235   M        -1.506  -1.427  -1.360  -1.315  -1.242  -1.139  -1.305  -1.205  -1.093
236   K        -0.787  -0.925  -0.941  -0.697  -0.900  -0.921  -0.736  -0.892  -0.886
237   L        -1.147  -1.142  -0.986  -1.186  -1.132  -0.925  -1.163  -1.124  -0.936
238   Y        -0.138  -0.352  -0.403   0.104  -0.234  -0.375  -0.166  -0.458  -0.536
239   D         1.308   1.334   1.388   1.314   1.347   1.440   1.399   1.432   1.512
240   Q         0.221   0.132   0.207   0.177  -0.003   0.084  -0.024  -0.199  -0.102
241   L        -0.138  -0.352  -0.403  -0.212  -0.525  -0.636  -0.166  -0.458  -0.536
242   L        -0.651  -0.618  -0.508  -0.974  -0.901  -0.730  -0.878  -0.825  -0.678
243   K        -1.011  -1.102  -0.979  -1.142  -1.278  -1.094  -1.020  -1.085  -0.929
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   E         0.221   0.132   0.207   0.036  -0.128  -0.016  -0.024  -0.199  -0.102
247   S         0.221   0.184   0.215   0.078  -0.020   0.022  -0.024  -0.103  -0.087
248   Y        -0.138  -0.159  -0.359   0.153   0.096  -0.202  -0.166  -0.211  -0.477
249   V        -1.011  -1.041  -0.959  -1.109  -1.163  -1.052  -1.020  -1.032  -0.909
250   D        -0.516  -0.558  -0.460  -0.682  -0.700  -0.555  -0.736  -0.753  -0.619
251   K        -0.787  -0.899  -0.929  -0.667  -0.842  -0.856  -0.736  -0.865  -0.874
252   H        -1.011  -0.961  -0.949  -0.874  -0.833  -0.789  -1.020  -0.941  -0.897
253   P        -0.138  -0.352  -0.403   0.024  -0.292  -0.389  -0.166  -0.458  -0.536
254   V        -0.787  -0.924  -0.938  -0.711  -0.927  -0.904  -0.736  -0.890  -0.883
255   V        -0.516  -0.569  -0.459  -0.753  -0.816  -0.657  -0.736  -0.770  -0.621
256   T         0.068   0.136   0.204  -0.231  -0.130  -0.008  -0.309  -0.192  -0.108
257   F        -0.428  -0.531  -0.455  -0.446  -0.604  -0.526  -0.593  -0.713  -0.614
258   N        -1.011  -0.911  -0.959  -0.895  -0.807  -0.849  -1.020  -0.915  -0.909
259   Q        -1.011  -1.073  -0.961  -1.058  -1.135  -0.973  -1.020  -1.052  -0.909
260   E         1.308   1.334   1.388   1.224   1.275   1.356   1.399   1.432   1.512
261   T        -1.011  -0.968  -0.949  -1.107  -1.050  -1.031  -1.020  -0.953  -0.898
262   D         1.308   1.334   1.388   1.314   1.347   1.440   1.399   1.432   1.512
263   V        -0.138   0.096  -0.325   0.147   0.458  -0.181  -0.166   0.151  -0.429
264   I         0.221   0.132   0.207   0.105  -0.079   0.013  -0.024  -0.199  -0.102
265   Y         1.308   1.334   1.388   1.467   1.501   1.583   1.399   1.432   1.512
266   Q        -1.371  -1.431  -1.368  -1.231  -1.363  -1.309  -1.163  -1.204  -1.099
267   N        -0.787  -0.818  -0.920  -0.621  -0.662  -0.864  -0.736  -0.770  -0.863
268   V        -0.138  -0.223  -0.375  -0.117  -0.244  -0.448  -0.166  -0.290  -0.497
269   S        -1.011  -1.091  -0.965  -1.028  -1.142  -0.955  -1.020  -1.072  -0.915
270   A        -2.226  -2.114  -1.974  -2.191  -2.018  -1.825  -1.590  -1.478  -1.307
271   E        -1.011  -0.974  -0.946  -1.024  -0.944  -0.906  -1.020  -0.953  -0.895
272   R        -1.011  -1.102  -0.979  -0.925  -1.074  -0.927  -1.020  -1.085  -0.929
273   A        -1.866  -1.739  -1.673  -1.757  -1.552  -1.495  -1.447  -1.317  -1.205
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   I        -0.138  -0.170  -0.358   0.004  -0.036  -0.343  -0.166  -0.212  -0.475
278   Q        -0.138  -0.352  -0.403   0.056  -0.264  -0.383  -0.166  -0.458  -0.536
279   I        -0.138   0.027  -0.330  -0.083   0.131  -0.323  -0.166   0.059  -0.436
280   V        -0.529  -0.599  -0.475  -0.688  -0.755  -0.577  -0.732  -0.799  -0.638
281   D        -0.529  -0.450  -0.469  -0.696  -0.607  -0.613  -0.732  -0.646  -0.632
282   K        -0.787  -0.924  -0.938  -0.787  -0.994  -1.070  -0.736  -0.890  -0.883
283   G        -0.138  -0.352  -0.403  -0.031  -0.340  -0.430  -0.166  -0.458  -0.536
284   V        -1.011  -0.883  -0.938  -1.025  -0.838  -0.895  -1.020  -0.886  -0.889
285   Q        -0.428  -0.273  -0.413  -0.480  -0.244  -0.451  -0.593  -0.386  -0.555
286   I        -1.011  -1.083  -0.962  -1.116  -1.167  -1.002  -1.020  -1.063  -0.911
287   H        -1.371  -1.431  -1.368  -0.987  -1.092  -1.022  -1.163  -1.204  -1.099
288   T         0.221   0.296   0.255   0.079   0.190   0.120  -0.024   0.100  -0.012
289   L         0.068   0.152   0.212  -0.362  -0.195  -0.114  -0.309  -0.161  -0.092
290   K        -1.371  -1.431  -1.368  -1.290  -1.408  -1.286  -1.163  -1.204  -1.099
291   R         1.308   1.334   1.388   1.501   1.529   1.614   1.399   1.432   1.512
292   Y        -1.506  -1.329  -1.358  -1.429  -1.162  -1.184  -1.305  -1.118  -1.092
293   N         1.308   1.334   1.388   1.351   1.395   1.475   1.399   1.432   1.512
294   L         0.563   0.478   0.355   0.484   0.398   0.200   0.545   0.407   0.170
295   P        -0.138  -0.352  -0.403   0.037  -0.265  -0.363  -0.166  -0.458  -0.536
296   D         0.563   0.418   0.344   0.653   0.456   0.336   0.545   0.308   0.151
297   T        -1.147  -1.008  -0.987  -1.345  -1.174  -1.079  -1.163  -1.004  -0.936
298   V         1.308   1.334   1.388   1.189   1.219   1.323   1.399   1.432   1.512
299   V         1.308   1.334   1.388   1.189   1.219   1.323   1.399   1.432   1.512
300   W         1.308   1.334   1.388   1.470   1.503   1.585   1.399   1.432   1.512
301   N         1.308   1.334   1.388   1.351   1.395   1.475   1.399   1.432   1.512
302   P         1.308   1.334   1.388   1.341   1.382   1.465   1.399   1.432   1.512
303   W         1.308   1.334   1.388   1.470   1.503   1.585   1.399   1.432   1.512
304   I        -0.651  -0.574  -0.483  -0.903  -0.762  -0.639  -0.878  -0.769  -0.646
305   E        -0.428  -0.264  -0.413  -0.587  -0.326  -0.552  -0.593  -0.376  -0.555
306   K         1.308   1.334   1.388   1.232   1.280   1.363   1.399   1.432   1.512
307   S         0.068   0.090   0.193  -0.147  -0.129   0.060  -0.309  -0.278  -0.128
308   Q        -1.011  -0.867  -0.943  -1.049  -0.838  -0.929  -1.020  -0.866  -0.894
309   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
310   M         0.221   0.214   0.226   0.275   0.252   0.193  -0.024  -0.047  -0.066
311   A         0.563   0.707   0.380   0.690   0.856   0.415   0.545   0.756   0.214
312   D         1.308   1.334   1.388   1.314   1.347   1.440   1.399   1.432   1.512
313   F         1.308   1.334   1.388   1.393   1.432   1.513   1.399   1.432   1.512
314   E        -0.138  -0.172  -0.363  -0.094  -0.134  -0.424  -0.166  -0.214  -0.481
315   P         1.308   1.334   1.388   1.341   1.382   1.465   1.399   1.432   1.512
316   K         1.308   1.334   1.388   1.232   1.280   1.363   1.399   1.432   1.512
317   T        -0.787  -0.725  -0.892  -0.641  -0.555  -0.822  -0.736  -0.659  -0.833
318   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
319   Y         0.068   0.096   0.191   0.005   0.054   0.194  -0.309  -0.266  -0.131
320   Q        -1.011  -0.894  -0.944  -0.902  -0.734  -0.761  -1.020  -0.890  -0.894
321   Q        -0.428  -0.420  -0.428  -0.359  -0.304  -0.341  -0.593  -0.556  -0.577
322   M         1.308   1.334   1.388   1.527   1.562   1.638   1.399   1.432   1.512
323   I        -0.651  -0.634  -0.509  -0.991  -0.952  -0.762  -0.878  -0.845  -0.680
324   C         1.308   1.334   1.388   1.572   1.604   1.680   1.399   1.432   1.512
325   I         0.068   0.107   0.195  -0.244  -0.174  -0.032  -0.309  -0.247  -0.125
326   E         1.308   1.334   1.388   1.224   1.275   1.356   1.399   1.432   1.512
327   P         0.563   0.478   0.355   0.682   0.574   0.382   0.545   0.407   0.170
328   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
329   H        -0.138  -0.352  -0.403   0.169  -0.147  -0.264  -0.166  -0.458  -0.536
330   V         1.308   1.334   1.388   1.189   1.219   1.323   1.399   1.432   1.512
331   H        -1.011  -0.807  -0.930  -0.874  -0.592  -0.761  -1.020  -0.772  -0.877
332   D        -1.371  -1.431  -1.368  -1.304  -1.437  -1.361  -1.163  -1.204  -1.099
333   F        -0.428  -0.441  -0.462  -0.279  -0.313  -0.305  -0.593  -0.632  -0.622
334   I        -1.011  -0.911  -0.959  -1.087  -0.921  -0.984  -1.020  -0.915  -0.909
335   S        -1.011  -0.974  -0.946  -1.145  -1.086  -1.027  -1.020  -0.953  -0.895
336   L         1.308   1.334   1.388   1.148   1.203   1.285   1.399   1.432   1.512
337   A        -1.011  -1.005  -0.951  -1.001  -0.996  -0.930  -1.020  -0.987  -0.900
338   P        -0.428  -0.389  -0.442  -0.426  -0.385  -0.457  -0.593  -0.547  -0.596
339   G         1.308   1.334   1.388   1.282   1.313   1.410   1.399   1.432   1.512
340   K        -1.506  -1.315  -1.358  -1.525  -1.221  -1.294  -1.305  -1.109  -1.092
341   K        -0.138  -0.192  -0.366  -0.071  -0.145  -0.393  -0.166  -0.251  -0.485
342   W         0.563   0.418   0.344   0.814   0.618   0.486   0.545   0.308   0.151
343   N        -1.011  -0.891  -0.956  -1.110  -0.969  -1.030  -1.020  -0.898  -0.907
344   A         0.068   0.175   0.227  -0.149   0.023   0.111  -0.309  -0.120  -0.063
345   Y        -1.011  -0.870  -0.936  -0.952  -0.794  -0.831  -1.020  -0.868  -0.886
346   Q         1.308   1.334   1.388   1.393   1.435   1.513   1.399   1.432   1.512
347   L        -0.948  -0.972  -0.961  -0.971  -1.022  -1.063  -0.926  -0.953  -0.907
348   L         0.152   0.106   0.193  -0.155  -0.211  -0.080  -0.151  -0.248  -0.128
349   C        -1.526  -1.466  -1.372  -1.391  -1.375  -1.160  -1.313  -1.238  -1.102
350   K        -0.948  -1.013  -0.979  -1.028  -1.161  -1.116  -0.926  -0.995  -0.926
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   E        -0.948  -0.697  -0.928  -0.915  -0.539  -0.903  -0.926  -0.616  -0.872
353   E         1.308   1.334   1.388   1.199   1.240   1.333   1.399   1.432   1.512
354   L         0.086   0.097   0.192  -0.293  -0.262  -0.105  -0.275  -0.265  -0.130
355   K         0.490   0.617   0.331   0.455   0.630   0.223   0.430   0.623   0.127
356   Y        -1.107  -1.092  -0.990  -1.107  -1.097  -0.928  -1.119  -1.081  -0.939
357   Q         0.221   0.132   0.207   0.177  -0.003   0.084  -0.024  -0.199  -0.102
358   A        -0.428  -0.383  -0.440  -0.472  -0.460  -0.525  -0.593  -0.553  -0.595
359   I        -1.506  -1.505  -1.376  -1.372  -1.312  -1.171  -1.305  -1.272  -1.106
360   Q        -1.526  -1.480  -1.377  -1.488  -1.409  -1.288  -1.313  -1.249  -1.107
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03161
Output conservation file - output/Q03161
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
