1     M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
2     T        -0.942  -0.917  -0.872  -1.005  -0.959  -0.944  -1.156  -1.124  -1.000
3     G        -1.647  -1.625  -1.400  -1.938  -1.883  -1.548  -1.633  -1.604  -1.301
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    E        -1.547  -1.538  -1.384  -1.600  -1.581  -1.349  -1.529  -1.515  -1.287
12    D        -1.445  -1.423  -1.375  -1.346  -1.311  -1.242  -1.439  -1.418  -1.278
13    F         0.154   0.171  -0.105   0.470   0.494   0.062   0.115   0.141  -0.324
14    K        -0.559  -0.652  -0.830  -0.405  -0.524  -0.766  -0.592  -0.718  -0.940
15    I        -0.559  -0.495  -0.812  -0.576  -0.482  -0.966  -0.592  -0.506  -0.917
16    K         0.154   0.166  -0.107   0.237   0.259  -0.118   0.115   0.132  -0.329
17    S        -0.193  -0.143  -0.169  -0.571  -0.497  -0.499  -0.450  -0.364  -0.438
18    G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
19    L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
20    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
21    Q         0.910   0.916   0.974   1.128   1.137   1.206   0.962   0.970   1.049
22    M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
23    L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
24    K         0.910   0.916   0.974   0.892   0.906   0.994   0.962   0.970   1.049
25    G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
26    G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
27    V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
28    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
29    M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
30    D         0.910   0.916   0.974   0.994   1.005   1.086   0.962   0.970   1.049
31    V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
32    V         0.154   0.036  -0.117   0.131  -0.019  -0.236   0.115  -0.066  -0.345
33    T        -0.349  -0.338  -0.210  -0.335  -0.316  -0.130  -0.733  -0.713  -0.512
34    P        -0.349  -0.346  -0.211  -0.747  -0.740  -0.479  -0.733  -0.726  -0.515
35    E        -0.559  -0.660  -0.829  -0.560  -0.731  -1.040  -0.592  -0.729  -0.939
36    Q         0.154   0.036  -0.117   0.426   0.260  -0.051   0.115  -0.066  -0.345
37    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
38    K        -0.853  -0.867  -0.868  -0.898  -0.924  -0.919  -1.015  -1.045  -0.993
39    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
40    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
41    E         0.154   0.166  -0.107   0.201   0.219  -0.148   0.115   0.132  -0.329
42    K        -1.080  -1.089  -0.907  -1.519  -1.540  -1.259  -1.298  -1.305  -1.040
43    S         0.154   0.217  -0.101  -0.073   0.001  -0.398   0.115   0.208  -0.317
44    G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
45    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
46    C         0.154   0.166  -0.107   0.470   0.487  -0.010   0.115   0.132  -0.329
47    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
48    V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
49    M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
50    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
51    L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
52    E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
53    S        -1.218  -1.141  -1.338  -0.921  -0.812  -1.137  -1.156  -1.063  -1.240
54    I         0.154   0.171  -0.105   0.199   0.227  -0.234   0.115   0.141  -0.324
55    P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
56    A         0.154   0.036  -0.117  -0.073  -0.234  -0.422   0.115  -0.066  -0.345
57    D         0.154   0.161  -0.106   0.292   0.306  -0.142   0.115   0.125  -0.327
58    M        -0.349  -0.355  -0.213  -0.498  -0.516  -0.301  -0.733  -0.744  -0.518
59    R         0.910   0.916   0.974   1.044   1.048   1.131   0.962   0.970   1.049
60    K        -0.349  -0.326  -0.205  -0.885  -0.851  -0.614  -0.733  -0.690  -0.503
61    S        -1.218  -1.290  -1.357  -1.023  -1.155  -1.310  -1.156  -1.238  -1.260
62    G         0.154   0.161  -0.106   0.178   0.186  -0.157   0.115   0.125  -0.327
63    K        -1.080  -1.036  -0.896  -1.270  -1.198  -0.973  -1.298  -1.234  -1.027
64    V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
65    C        -0.349  -0.355  -0.213  -0.569  -0.620  -0.402  -0.733  -0.744  -0.518
66    R         0.910   0.916   0.974   1.044   1.048   1.131   0.962   0.970   1.049
67    M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
68    S         0.910   0.916   0.974   1.009   1.026   1.099   0.962   0.970   1.049
69    D         0.154   0.036  -0.117   0.342   0.196  -0.039   0.115  -0.066  -0.345
70    P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
71    K        -0.853  -0.882  -0.875  -0.983  -1.027  -1.074  -1.015  -1.060  -1.002
72    M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
73    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
74    K         0.910   0.916   0.974   0.892   0.906   0.994   0.962   0.970   1.049
75    D        -0.193  -0.156  -0.175  -0.336  -0.272  -0.319  -0.450  -0.387  -0.449
76    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
77    M        -0.193  -0.243  -0.193  -0.101  -0.183  -0.132  -0.450  -0.540  -0.481
78    N        -0.853  -0.811  -0.858  -1.118  -1.067  -1.073  -1.015  -0.949  -0.979
79    S        -1.080  -1.036  -0.896  -1.411  -1.360  -1.086  -1.298  -1.234  -1.027
80    V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
81    S        -0.559  -0.660  -0.829  -0.337  -0.468  -0.774  -0.592  -0.729  -0.939
82    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
83    P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
84    V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
85    M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
86    A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
87    K         0.910   0.916   0.974   0.892   0.906   0.994   0.962   0.970   1.049
88    V        -0.942  -1.003  -0.876  -1.073  -1.174  -1.011  -1.156  -1.211  -1.004
89    R         0.910   0.916   0.974   1.044   1.048   1.131   0.962   0.970   1.049
90    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
91    G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
92    H         0.910   0.916   0.974   1.184   1.193   1.257   0.962   0.970   1.049
93    F         0.154   0.036  -0.117   0.426   0.258  -0.066   0.115  -0.066  -0.345
94    V        -0.193  -0.247  -0.196  -0.363  -0.446  -0.355  -0.450  -0.547  -0.488
95    E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
96    A        -0.559  -0.660  -0.829  -0.690  -0.821  -0.978  -0.592  -0.729  -0.939
97    Q         0.154   0.036  -0.117   0.456   0.299   0.023   0.115  -0.066  -0.345
98    I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
99    I        -0.193  -0.154  -0.183  -0.314  -0.238  -0.333  -0.450  -0.382  -0.463
100   E         0.154   0.185  -0.105   0.201   0.242  -0.145   0.115   0.161  -0.325
101   A        -1.218  -1.290  -1.357  -1.357  -1.449  -1.475  -1.156  -1.238  -1.260
102   L        -0.193  -0.178  -0.177  -0.314  -0.279  -0.323  -0.450  -0.423  -0.453
103   E        -0.349  -0.315  -0.202  -0.719  -0.652  -0.466  -0.733  -0.670  -0.498
104   V         0.154   0.185  -0.105   0.103   0.149  -0.285   0.115   0.161  -0.325
105   D         0.910   0.916   0.974   0.994   1.005   1.086   0.962   0.970   1.049
106   Y         0.910   0.916   0.974   1.206   1.214   1.276   0.962   0.970   1.049
107   I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
108   D         0.910   0.916   0.974   0.994   1.005   1.086   0.962   0.970   1.049
109   E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
110   S         0.910   0.916   0.974   1.009   1.026   1.099   0.962   0.970   1.049
111   E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
112   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
113   L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
114   T         0.910   0.916   0.974   1.069   1.076   1.153   0.962   0.970   1.049
115   P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
116   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
117   D         0.910   0.916   0.974   0.994   1.005   1.086   0.962   0.970   1.049
118   W        -1.949  -1.907  -1.767  -1.597  -1.543  -1.372  -1.721  -1.677  -1.447
119   T        -2.314  -2.263  -2.078  -2.108  -2.011  -1.812  -1.863  -1.812  -1.552
120   H        -1.445  -1.398  -1.366  -1.086  -1.008  -1.017  -1.439  -1.379  -1.270
121   H         0.910   0.916   0.974   1.184   1.193   1.257   0.962   0.970   1.049
122   I         0.154   0.036  -0.117   0.199   0.034  -0.257   0.115  -0.066  -0.345
123   E        -1.949  -1.974  -1.764  -1.848  -1.849  -1.533  -1.721  -1.731  -1.445
124   K         0.910   0.916   0.974   0.892   0.906   0.994   0.962   0.970   1.049
125   D        -1.811  -1.775  -1.746  -1.474  -1.418  -1.386  -1.580  -1.538  -1.429
126   K        -1.080  -1.080  -0.903  -1.169  -1.152  -0.889  -1.298  -1.293  -1.035
127   F         0.910   0.916   0.974   1.138   1.147   1.215   0.962   0.970   1.049
128   K        -0.559  -0.519  -0.813  -0.399  -0.341  -0.732  -0.592  -0.537  -0.919
129   V         0.154   0.036  -0.117   0.052  -0.127  -0.435   0.115  -0.066  -0.345
130   P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
131   F         0.910   0.916   0.974   1.138   1.147   1.215   0.962   0.970   1.049
132   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
133   C         0.910   0.916   0.974   1.182   1.189   1.254   0.962   0.970   1.049
134   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
135   A        -0.559  -0.652  -0.830  -0.690  -0.810  -0.979  -0.592  -0.718  -0.940
136   K        -0.349  -0.325  -0.208  -0.515  -0.463  -0.301  -0.733  -0.689  -0.509
137   D        -0.193  -0.143  -0.169  -0.052   0.035  -0.075  -0.450  -0.364  -0.438
138   L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
139   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
140   E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
141   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
142   L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
143   R         0.910   0.916   0.974   1.044   1.048   1.131   0.962   0.970   1.049
144   R         0.910   0.916   0.974   1.044   1.048   1.131   0.962   0.970   1.049
145   I         0.154   0.212  -0.102   0.199   0.281  -0.229   0.115   0.200  -0.320
146   N        -1.949  -1.966  -1.767  -1.690  -1.713  -1.458  -1.721  -1.725  -1.447
147   E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
148   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
149   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
150   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
151   M         0.154   0.166  -0.107   0.396   0.413   0.015   0.115   0.132  -0.329
152   I         0.154   0.212  -0.102   0.218   0.299  -0.183   0.115   0.200  -0.320
153   R         0.910   0.916   0.974   1.044   1.048   1.131   0.962   0.970   1.049
154   T         0.154   0.161  -0.106   0.420   0.430   0.048   0.115   0.125  -0.327
155   K         0.910   0.916   0.974   0.892   0.906   0.994   0.962   0.970   1.049
156   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
157   E         0.910   0.916   0.974   0.856   0.865   0.962   0.962   0.970   1.049
158   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
159   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
160   T         0.910   0.916   0.974   1.069   1.076   1.153   0.962   0.970   1.049
161   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
162   D         0.910   0.916   0.974   0.994   1.005   1.086   0.962   0.970   1.049
163   V         0.154   0.212  -0.102   0.103   0.183  -0.279   0.115   0.200  -0.320
164   S        -0.853  -0.882  -0.875  -0.867  -0.929  -0.923  -1.015  -1.060  -1.002
165   E         0.154   0.161  -0.106   0.180   0.193  -0.195   0.115   0.125  -0.327
166   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
167   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
168   K        -1.218  -1.160  -1.335  -1.062  -0.972  -1.230  -1.156  -1.085  -1.236
169   H         0.910   0.916   0.974   1.184   1.193   1.257   0.962   0.970   1.049
170   I        -0.559  -0.537  -0.822  -0.403  -0.368  -0.773  -0.592  -0.560  -0.930
171   R        -0.559  -0.482  -0.811  -0.285  -0.186  -0.683  -0.592  -0.488  -0.916
172   R        -1.811  -1.708  -1.740  -1.496  -1.336  -1.442  -1.580  -1.472  -1.424
173   I        -0.559  -0.652  -0.830  -0.457  -0.597  -0.896  -0.592  -0.718  -0.940
174   T        -1.445  -1.469  -1.374  -1.298  -1.311  -1.147  -1.439  -1.457  -1.278
175   E        -2.314  -2.296  -2.082  -2.287  -2.302  -1.995  -1.863  -1.841  -1.555
176   E        -0.559  -0.504  -0.815  -0.455  -0.383  -0.802  -0.592  -0.518  -0.921
177   I         0.154   0.171  -0.105   0.218   0.247  -0.187   0.115   0.141  -0.324
178   K        -2.314  -2.316  -2.088  -2.240  -2.286  -1.919  -1.863  -1.855  -1.559
179   A        -2.314  -2.294  -2.084  -2.188  -2.133  -1.849  -1.863  -1.839  -1.556
180   C        -1.811  -1.739  -1.747  -1.824  -1.744  -1.623  -1.580  -1.502  -1.430
181   Q        -1.949  -1.907  -1.767  -1.774  -1.716  -1.525  -1.721  -1.677  -1.447
182   Q        -2.314  -2.309  -2.083  -2.090  -2.126  -1.787  -1.863  -1.850  -1.555
183   L        -1.445  -1.488  -1.377  -1.473  -1.561  -1.397  -1.439  -1.474  -1.281
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   K        -0.843  -0.916  -0.878  -0.977  -1.106  -1.076  -0.976  -1.080  -1.004
188   S        -0.853  -0.881  -0.867  -0.854  -0.912  -0.894  -1.015  -1.058  -0.993
189   E        -0.559  -0.519  -0.813  -0.462  -0.406  -0.813  -0.592  -0.537  -0.919
190   D        -1.811  -1.837  -1.752  -1.704  -1.742  -1.698  -1.580  -1.602  -1.434
191   D        -1.218  -1.241  -1.346  -1.188  -1.258  -1.423  -1.156  -1.185  -1.248
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   I        -1.080  -1.083  -0.904  -1.371  -1.374  -1.104  -1.298  -1.297  -1.036
195   A        -1.445  -1.416  -1.366  -1.638  -1.602  -1.492  -1.439  -1.401  -1.269
196   K        -1.949  -1.904  -1.764  -1.935  -1.861  -1.696  -1.721  -1.676  -1.444
197   V        -1.811  -1.823  -1.754  -1.424  -1.440  -1.449  -1.580  -1.588  -1.436
198   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
199   E        -1.080  -1.089  -0.904  -1.293  -1.293  -1.004  -1.298  -1.305  -1.037
200   E         0.154   0.185  -0.105   0.180   0.224  -0.194   0.115   0.161  -0.325
201   M        -0.853  -0.778  -0.854  -0.910  -0.792  -0.897  -1.015  -0.917  -0.975
202   R        -0.942  -0.921  -0.871  -1.156  -1.136  -1.083  -1.156  -1.125  -0.998
203   V        -0.349  -0.355  -0.213  -0.907  -0.939  -0.678  -0.733  -0.744  -0.518
204   P        -0.853  -0.926  -0.868  -0.712  -0.806  -0.769  -1.015  -1.094  -0.993
205   V        -2.314  -2.263  -2.078  -2.089  -2.017  -1.730  -1.863  -1.812  -1.552
206   S        -1.445  -1.362  -1.362  -1.487  -1.364  -1.344  -1.439  -1.348  -1.265
207   L         0.154   0.212  -0.102   0.247   0.327  -0.118   0.115   0.200  -0.320
208   L         0.154   0.171  -0.105   0.201   0.233  -0.231   0.115   0.141  -0.324
209   K        -0.559  -0.504  -0.815  -0.437  -0.359  -0.808  -0.592  -0.518  -0.921
210   D        -2.314  -2.309  -2.083  -2.086  -2.081  -1.742  -1.863  -1.850  -1.555
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   V        -1.445  -1.420  -1.373  -1.443  -1.399  -1.275  -1.439  -1.416  -1.277
213   L        -0.853  -0.811  -0.858  -1.230  -1.163  -1.184  -1.015  -0.949  -0.979
214   E        -1.811  -1.743  -1.745  -1.625  -1.528  -1.505  -1.580  -1.506  -1.429
215   K        -1.583  -1.554  -1.387  -1.705  -1.652  -1.369  -1.580  -1.544  -1.291
216   G         0.154   0.161  -0.106   0.132   0.141  -0.267   0.115   0.125  -0.327
217   K        -0.349  -0.355  -0.213  -0.546  -0.549  -0.320  -0.733  -0.744  -0.518
218   L         0.154   0.212  -0.102   0.259   0.338  -0.090   0.115   0.200  -0.320
219   P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
220   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
221   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
222   N         0.154   0.161  -0.106   0.464   0.475   0.015   0.115   0.125  -0.327
223   F         0.910   0.916   0.974   1.138   1.147   1.215   0.962   0.970   1.049
224   A         0.154   0.161  -0.106  -0.041  -0.039  -0.329   0.115   0.125  -0.327
225   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
226   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
227   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
228   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
229   A         0.154   0.161  -0.106  -0.073  -0.069  -0.406   0.115   0.125  -0.327
230   T         0.910   0.916   0.974   1.069   1.076   1.153   0.962   0.970   1.049
231   P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
232   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
233   D         0.910   0.916   0.974   0.994   1.005   1.086   0.962   0.970   1.049
234   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
235   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
236   L         0.910   0.916   0.974   0.913   0.927   1.013   0.962   0.970   1.049
237   L        -1.080  -1.079  -0.906  -1.097  -1.090  -0.822  -1.298  -1.293  -1.038
238   M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
239   Q         0.154   0.036  -0.117   0.426   0.260  -0.051   0.115  -0.066  -0.345
240   L         0.154   0.036  -0.117   0.259   0.116  -0.112   0.115  -0.066  -0.345
241   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
242   C         0.910   0.916   0.974   1.182   1.189   1.254   0.962   0.970   1.049
243   D         0.154   0.185  -0.105   0.292   0.338  -0.140   0.115   0.161  -0.325
244   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
245   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
246   F         0.910   0.916   0.974   1.138   1.147   1.215   0.962   0.970   1.049
247   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
248   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
249   S         0.910   0.916   0.974   1.009   1.026   1.099   0.962   0.970   1.049
250   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
251   I         0.910   0.916   0.974   0.910   0.921   1.010   0.962   0.970   1.049
252   F         0.910   0.916   0.974   1.138   1.147   1.215   0.962   0.970   1.049
253   K        -0.193  -0.178  -0.177  -0.333  -0.298  -0.337  -0.450  -0.423  -0.453
254   S        -0.559  -0.656  -0.829  -0.364  -0.495  -0.830  -0.592  -0.724  -0.939
255   S        -1.949  -1.970  -1.772  -1.977  -2.038  -1.740  -1.721  -1.729  -1.450
256   N        -0.853  -0.924  -0.868  -0.686  -0.788  -0.774  -1.015  -1.091  -0.993
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   P         0.910   0.916   0.974   1.096   1.105   1.177   0.962   0.970   1.049
259   V        -0.853  -0.793  -0.857  -1.165  -1.069  -1.207  -1.015  -0.939  -0.978
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   R        -1.811  -1.803  -1.747  -1.663  -1.636  -1.576  -1.580  -1.571  -1.430
264   L        -0.349  -0.355  -0.213  -0.530  -0.533  -0.306  -0.733  -0.744  -0.518
265   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
266   T        -0.942  -0.894  -0.870  -0.999  -0.929  -0.849  -1.156  -1.101  -0.998
267   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
268   V        -0.193  -0.225  -0.194  -0.360  -0.418  -0.421  -0.450  -0.506  -0.483
269   V         0.910   0.916   0.974   0.796   0.807   0.908   0.962   0.970   1.049
270   E        -1.949  -1.970  -1.772  -1.744  -1.775  -1.487  -1.721  -1.729  -1.450
271   A         0.910   0.916   0.974   0.603   0.603   0.735   0.962   0.970   1.049
272   T        -0.349  -0.326  -0.205  -0.609  -0.571  -0.365  -0.733  -0.690  -0.503
273   T         0.154   0.036  -0.117   0.328   0.145  -0.199   0.115  -0.066  -0.345
274   H         0.154   0.036  -0.117   0.530   0.379   0.113   0.115  -0.066  -0.345
275   F        -0.559  -0.611  -0.823  -0.067  -0.135  -0.462  -0.592  -0.667  -0.931
276   D        -0.942  -0.923  -0.873  -0.888  -0.840  -0.789  -1.156  -1.126  -1.001
277   N         0.154   0.217  -0.101   0.342   0.423  -0.014   0.115   0.208  -0.317
278   P        -0.559  -0.640  -0.826  -0.278  -0.381  -0.757  -0.592  -0.702  -0.936
279   S        -1.811  -1.823  -1.754  -1.806  -1.835  -1.777  -1.580  -1.588  -1.436
280   K        -1.811  -1.847  -1.760  -1.838  -1.933  -1.833  -1.580  -1.610  -1.441
281   L         0.154   0.212  -0.102   0.201   0.287  -0.227   0.115   0.200  -0.320
282   L        -1.445  -1.472  -1.377  -1.681  -1.737  -1.567  -1.439  -1.460  -1.280
283   E        -0.559  -0.529  -0.814  -0.476  -0.430  -0.841  -0.592  -0.549  -0.919
284   V        -0.853  -0.918  -0.866  -0.976  -1.088  -1.019  -1.015  -1.083  -0.990
285   S         0.154   0.036  -0.117   0.361   0.222  -0.017   0.115  -0.066  -0.345
286   S        -1.445  -1.486  -1.372  -1.344  -1.399  -1.281  -1.439  -1.470  -1.276
287   D        -0.853  -0.931  -0.875  -0.767  -0.878  -0.825  -1.015  -1.102  -1.000
288   L         0.154   0.036  -0.117   0.267   0.127  -0.093   0.115  -0.066  -0.345
289   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
290   E        -1.218  -1.178  -1.341  -1.181  -1.119  -1.402  -1.156  -1.105  -1.242
291   L        -0.349  -0.355  -0.213  -0.804  -0.837  -0.594  -0.733  -0.744  -0.518
292   M         0.910   0.916   0.974   1.052   1.059   1.137   0.962   0.970   1.049
293   G        -1.445  -1.472  -1.377  -1.591  -1.636  -1.436  -1.439  -1.460  -1.280
294   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
295   V        -1.583  -1.553  -1.388  -1.726  -1.667  -1.422  -1.580  -1.543  -1.291
296   S        -0.559  -0.546  -0.817  -0.391  -0.365  -0.863  -0.592  -0.572  -0.924
297   I        -0.942  -1.004  -0.880  -1.143  -1.194  -0.967  -1.156  -1.211  -1.008
298   E        -1.445  -1.489  -1.373  -1.572  -1.659  -1.483  -1.439  -1.473  -1.276
299   S         0.154   0.036  -0.117   0.303   0.143  -0.161   0.115  -0.066  -0.345
300   I        -0.853  -0.916  -0.865  -0.909  -0.974  -0.914  -1.015  -1.080  -0.988
301   S        -1.218  -1.152  -1.336  -1.095  -0.993  -1.286  -1.156  -1.076  -1.238
302   H        -1.949  -1.946  -1.763  -1.982  -1.966  -1.612  -1.721  -1.710  -1.444
303   A        -1.949  -1.901  -1.762  -1.970  -1.887  -1.706  -1.721  -1.672  -1.443
304   S        -0.559  -0.495  -0.812  -0.480  -0.391  -0.846  -0.592  -0.506  -0.917
305   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   R        -0.349  -0.349  -0.211  -0.546  -0.541  -0.320  -0.733  -0.732  -0.515
309   L        -0.559  -0.616  -0.823  -0.454  -0.524  -0.883  -0.592  -0.673  -0.932
310   S        -0.853  -0.799  -0.855  -1.195  -1.114  -1.149  -1.015  -0.931  -0.975
311   E        -2.314  -2.309  -2.083  -2.072  -2.080  -1.784  -1.863  -1.850  -1.555
312   I        -0.193  -0.143  -0.169  -0.189  -0.103  -0.203  -0.450  -0.364  -0.438
313   G         0.910   0.916   0.974   0.828   0.833   0.936   0.962   0.970   1.049
314   W         0.910   0.916   0.974   1.245   1.252   1.311   0.962   0.970   1.049
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03148
Output conservation file - output/Q03148
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
