1     M         1.974   2.009   2.127   2.276   2.326   2.534   2.259   2.314   2.531
2     V        -0.364  -0.323  -0.374  -0.517  -0.476  -0.502  -0.508  -0.471  -0.483
3     L        -1.365  -1.321  -1.226  -1.382  -1.291  -1.152  -1.123  -1.070  -0.940
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -         1.011   0.847   0.907   1.145   0.827   0.891   0.931   0.591   0.638
10    -         1.011   1.065   0.946   0.918   1.030   0.759   0.931   1.017   0.721
11    -        -0.589  -0.522  -0.491  -0.739  -0.593  -0.578  -0.730  -0.661  -0.608
12    A        -0.360  -0.415  -0.379  -0.339  -0.416  -0.371  -0.465  -0.509  -0.469
13    K        -0.364  -0.456  -0.395  -0.504  -0.613  -0.521  -0.508  -0.595  -0.505
14    Q         0.045  -0.009  -0.229   0.460   0.369   0.029   0.107   0.021  -0.269
15    W        -0.364  -0.386  -0.375  -0.527  -0.568  -0.520  -0.508  -0.529  -0.485
16    V        -0.772  -0.785  -0.800  -0.803  -0.825  -0.836  -0.713  -0.726  -0.714
17    L         0.955   0.892   0.892   0.804   0.684   0.646   0.824   0.682   0.606
18    K        -0.237  -0.176  -0.290  -0.273  -0.167  -0.340  -0.303  -0.197  -0.353
19    N        -1.068  -1.080  -1.145  -0.665  -0.709  -0.807  -0.816  -0.833  -0.860
20    L        -1.661  -1.664  -1.542  -1.240  -1.228  -1.039  -1.226  -1.210  -1.061
21    P         1.303   1.179   1.118   1.564   1.387   1.300   1.439   1.224   1.072
22    T        -0.772  -0.830  -0.828  -0.744  -0.826  -0.862  -0.713  -0.772  -0.737
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    E        -0.956  -0.922  -0.856  -1.112  -1.025  -0.908  -0.918  -0.872  -0.771
28    P        -0.475  -0.343  -0.366  -0.363  -0.143  -0.186  -0.611  -0.424  -0.454
29    F        -0.067  -0.034   0.082  -0.381  -0.327  -0.157  -0.406  -0.362  -0.212
30    N         0.305   0.268   0.186   0.564   0.511   0.394   0.184   0.118  -0.044
31    F        -0.584  -0.538  -0.496  -0.656  -0.572  -0.497  -0.739  -0.676  -0.615
32    H        -0.417  -0.464  -0.460  -0.478  -0.545  -0.522  -0.508  -0.572  -0.571
33    F        -1.008  -1.018  -0.896  -1.035  -1.094  -0.933  -0.960  -0.958  -0.805
34    H        -0.102  -0.059   0.054  -0.266  -0.200  -0.025  -0.452  -0.395  -0.253
35    D        -0.533  -0.519  -0.728  -0.300  -0.274  -0.662  -0.406  -0.387  -0.622
36    P        -0.956  -0.910  -0.842  -0.827  -0.723  -0.651  -0.918  -0.853  -0.756
37    A        -0.844  -0.917  -0.836  -0.942  -1.060  -0.960  -0.816  -0.868  -0.752
38    C        -0.246  -0.365  -0.419  -0.099  -0.250  -0.327  -0.282  -0.445  -0.519
39    T         1.303   1.179   1.118   1.522   1.369   1.272   1.439   1.224   1.072
40    F         1.974   2.009   2.127   2.152   2.205   2.410   2.259   2.314   2.531
41    E        -0.844  -0.797  -0.806  -0.695  -0.637  -0.661  -0.816  -0.757  -0.722
42    L        -1.253  -1.272  -1.210  -1.380  -1.412  -1.334  -1.021  -1.018  -0.922
43    I        -1.253  -1.309  -1.226  -1.236  -1.293  -1.225  -1.021  -1.054  -0.938
44    E        -1.068  -0.915  -1.114  -0.642  -0.458  -0.698  -0.816  -0.655  -0.831
45    K        -0.956  -0.912  -0.862  -1.177  -1.103  -1.009  -0.918  -0.864  -0.775
46    E        -1.253  -1.215  -1.194  -1.019  -0.953  -0.938  -1.021  -0.971  -0.912
47    L        -0.956  -0.949  -0.881  -1.060  -1.100  -1.016  -0.918  -0.907  -0.796
48    S        -0.364  -0.404  -0.375  -0.294  -0.331  -0.298  -0.508  -0.530  -0.479
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    S        -1.008  -1.023  -0.877  -1.125  -1.155  -0.937  -0.960  -0.962  -0.789
51    E        -1.234  -1.297  -1.226  -1.000  -1.102  -1.049  -0.984  -1.037  -0.936
52    Q        -0.956  -0.931  -0.848  -0.970  -0.910  -0.795  -0.918  -0.868  -0.758
53    L         0.341   0.357   0.296   0.209   0.271   0.150   0.209   0.258   0.131
54    K         0.045  -0.108  -0.254   0.134  -0.075  -0.303   0.107  -0.103  -0.302
55    D         0.652   0.677   0.807   0.432   0.469   0.666   0.209   0.236   0.420
56    G         1.303   1.179   1.118   1.279   1.125   1.054   1.439   1.224   1.072
57    E        -0.237  -0.320  -0.366  -0.062  -0.196  -0.242  -0.303  -0.420  -0.461
58    L        -0.237  -0.191  -0.319  -0.289  -0.253  -0.395  -0.303  -0.261  -0.404
59    L         0.341   0.542   0.333   0.194   0.513   0.188   0.209   0.525   0.191
60    L        -0.548  -0.461  -0.431  -0.929  -0.796  -0.750  -0.713  -0.611  -0.550
61    E         0.749   0.759   0.840   0.451   0.461   0.572   0.414   0.410   0.493
62    T        -0.364  -0.349  -0.358  -0.374  -0.333  -0.320  -0.508  -0.482  -0.463
63    T        -0.533  -0.655  -0.772  -0.392  -0.587  -0.757  -0.406  -0.551  -0.672
64    Y         1.303   1.301   1.138   1.576   1.577   1.346   1.439   1.431   1.110
65    L        -0.533  -0.619  -0.746  -0.425  -0.570  -0.771  -0.406  -0.515  -0.641
66    S         1.974   2.009   2.127   1.989   2.058   2.248   2.259   2.314   2.531
67    N         0.341   0.197   0.192   0.416   0.170   0.100   0.209  -0.008  -0.047
68    D         1.974   2.009   2.127   2.077   2.136   2.335   2.259   2.314   2.531
69    P         1.974   2.009   2.127   2.175   2.219   2.433   2.259   2.314   2.531
70    A         0.117   0.055   0.162  -0.003  -0.067   0.104  -0.201  -0.259  -0.114
71    Q         0.341   0.230   0.185   0.555   0.343   0.267   0.209   0.021  -0.061
72    K         0.749   0.808   0.858   0.699   0.803   0.820   0.414   0.512   0.532
73    F        -0.772  -0.776  -0.819  -0.743  -0.740  -0.776  -0.713  -0.719  -0.727
74    W         0.658   0.514   0.347   1.186   1.006   0.777   0.722   0.496   0.216
75    I        -0.067  -0.032   0.057  -0.189  -0.142  -0.044  -0.406  -0.359  -0.250
76    S        -0.483  -0.460  -0.445  -0.320  -0.291  -0.305  -0.621  -0.583  -0.556
77    -         0.679   0.676   0.807   0.233   0.216   0.413   0.267   0.233   0.421
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    S        -0.364  -0.398  -0.387  -0.389  -0.430  -0.395  -0.508  -0.544  -0.497
81    M        -1.957  -1.858  -1.794  -1.892  -1.755  -1.669  -1.328  -1.243  -1.137
82    D        -1.661  -1.652  -1.565  -1.478  -1.415  -1.293  -1.226  -1.202  -1.077
83    K        -0.364  -0.400  -0.388  -0.326  -0.414  -0.365  -0.508  -0.545  -0.498
84    N        -0.475  -0.327  -0.364  -0.395  -0.194  -0.204  -0.611  -0.422  -0.452
85    Y         1.974   2.009   2.127   2.187   2.238   2.445   2.259   2.314   2.531
86    A        -0.772  -0.739  -0.804  -0.773  -0.777  -0.851  -0.713  -0.697  -0.717
87    K         0.099   0.143   0.165  -0.043   0.035   0.076  -0.206  -0.138  -0.102
88    G         0.341   0.445   0.277   0.485   0.600   0.392   0.209   0.342   0.096
89    V         0.171   0.159   0.202  -0.127  -0.105  -0.067  -0.098  -0.073  -0.033
90    Q        -1.365  -1.308  -1.228  -1.274  -1.176  -1.048  -1.123  -1.061  -0.942
91    P        -0.772  -0.835  -0.851  -0.735  -0.885  -0.927  -0.713  -0.787  -0.766
92    G         0.955   1.124   1.061   0.803   1.051   0.970   0.824   1.125   0.958
93    E        -0.844  -0.827  -0.835  -0.820  -0.805  -0.816  -0.816  -0.789  -0.751
94    I         0.171   0.175   0.157   0.090   0.063   0.025  -0.098  -0.105  -0.118
95    I        -0.475  -0.470  -0.395  -0.414  -0.370  -0.289  -0.611  -0.584  -0.492
96    P        -1.253  -1.154  -1.188  -0.899  -0.774  -0.824  -1.021  -0.933  -0.904
97    A         0.171   0.137   0.195   0.007   0.002   0.074  -0.098  -0.113  -0.052
98    R        -0.772  -0.896  -0.863  -0.637  -0.801  -0.714  -0.713  -0.835  -0.773
99    G         0.658   0.492   0.341   0.734   0.522   0.340   0.722   0.465   0.205
100   I         0.171   0.075   0.149  -0.113  -0.265  -0.161  -0.098  -0.223  -0.127
101   G         0.171   0.135   0.175  -0.072  -0.129  -0.024  -0.098  -0.155  -0.096
102   K        -0.364  -0.348  -0.382  -0.403  -0.406  -0.387  -0.508  -0.494  -0.493
103   V         0.749   0.867   0.899   0.414   0.628   0.642   0.414   0.632   0.622
104   L         0.171   0.226   0.176  -0.155  -0.093  -0.148  -0.098  -0.042  -0.087
105   A        -1.253  -1.147  -1.196  -1.184  -1.074  -1.113  -1.021  -0.924  -0.915
106   S         1.974   2.009   2.127   1.989   2.058   2.248   2.259   2.314   2.531
107   R        -0.237  -0.310  -0.346  -0.203  -0.304  -0.323  -0.303  -0.405  -0.439
108   N         0.171   0.079   0.151   0.047  -0.081   0.016  -0.098  -0.216  -0.124
109   K        -0.772  -0.836  -0.828  -0.699  -0.799  -0.799  -0.713  -0.785  -0.740
110   A        -0.533  -0.613  -0.732  -0.371  -0.485  -0.639  -0.406  -0.505  -0.627
111   F        -0.548  -0.488  -0.413  -0.418  -0.347  -0.226  -0.713  -0.631  -0.525
112   S        -0.364  -0.348  -0.373  -0.533  -0.531  -0.528  -0.508  -0.494  -0.482
113   P        -0.364  -0.347  -0.358  -0.503  -0.477  -0.475  -0.508  -0.492  -0.467
114   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
115   D         1.303   1.179   1.118   1.511   1.371   1.305   1.439   1.224   1.072
116   Y        -0.772  -0.772  -0.794  -0.748  -0.709  -0.743  -0.713  -0.691  -0.697
117   V         1.303   1.386   1.151   1.290   1.409   1.099   1.439   1.568   1.136
118   S        -0.364  -0.373  -0.369  -0.414  -0.425  -0.402  -0.508  -0.504  -0.473
119   A         0.171   0.075   0.149  -0.105  -0.240  -0.109  -0.098  -0.223  -0.127
120   V        -0.364  -0.348  -0.366  -0.302  -0.320  -0.316  -0.508  -0.494  -0.475
121   T        -1.365  -1.388  -1.265  -1.298  -1.332  -1.181  -1.123  -1.120  -0.971
122   G        -0.533  -0.246  -0.678  -0.462  -0.072  -0.689  -0.406  -0.057  -0.565
123   W         0.658   0.603   0.361   1.141   1.076   0.706   0.722   0.636   0.238
124   T        -1.661  -1.572  -1.534  -1.436  -1.312  -1.271  -1.226  -1.148  -1.056
125   T        -0.237  -0.170  -0.311  -0.117   0.005  -0.235  -0.303  -0.203  -0.386
126   H         0.341   0.315   0.240   0.595   0.557   0.439   0.209   0.171   0.036
127   A        -1.549  -1.480  -1.479  -1.416  -1.314  -1.354  -1.123  -1.062  -1.010
128   I         0.117   0.065   0.151  -0.184  -0.206  -0.068  -0.201  -0.241  -0.122
129   I        -0.364  -0.362  -0.369  -0.681  -0.683  -0.699  -0.508  -0.499  -0.479
130   S        -1.253  -1.124  -1.163  -1.075  -0.879  -0.938  -1.021  -0.877  -0.879
131   Q        -0.772  -0.792  -0.780  -0.615  -0.638  -0.622  -0.713  -0.713  -0.682
132   E        -1.253  -1.180  -1.168  -0.973  -0.849  -0.871  -1.021  -0.940  -0.890
133   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   Q        -1.360  -1.360  -1.235  -1.308  -1.315  -1.103  -1.114  -1.100  -0.947
136   G        -0.901  -0.867  -0.860  -0.958  -0.909  -0.925  -0.854  -0.820  -0.774
137   L        -1.253  -1.145  -1.191  -1.066  -0.929  -0.943  -1.021  -0.903  -0.909
138   R        -1.068  -1.069  -0.906  -0.988  -0.965  -0.749  -1.021  -1.002  -0.819
139   K        -0.475  -0.393  -0.396  -0.607  -0.494  -0.482  -0.611  -0.523  -0.500
140   L         0.341   0.315   0.240   0.277   0.240   0.092   0.209   0.171   0.036
141   D         0.045  -0.133  -0.282   0.368   0.127  -0.090   0.107  -0.135  -0.340
142   K        -1.068  -0.989  -0.897  -1.225  -1.108  -0.981  -1.021  -0.940  -0.810
143   N        -0.772  -0.825  -0.849  -0.651  -0.730  -0.749  -0.713  -0.779  -0.764
144   K        -0.956  -0.944  -0.883  -1.086  -1.066  -0.949  -0.918  -0.906  -0.797
145   V         0.341   0.234   0.226   0.128  -0.044  -0.097   0.209   0.056   0.013
146   G        -0.237  -0.264  -0.366  -0.387  -0.451  -0.646  -0.303  -0.344  -0.464
147   K         0.341   0.334   0.210   0.464   0.425   0.198   0.209   0.184  -0.022
148   L         0.658   0.632   0.381   0.759   0.727   0.400   0.722   0.678   0.271
149   W        -0.844  -0.892  -0.839  -0.716  -0.773  -0.690  -0.816  -0.846  -0.755
150   W        -0.956  -0.807  -0.843  -0.796  -0.567  -0.600  -0.918  -0.755  -0.753
151   Y        -0.237  -0.323  -0.366   0.001  -0.151  -0.231  -0.303  -0.419  -0.465
152   L         1.303   1.179   1.118   1.298   1.130   1.036   1.439   1.224   1.072
153   S         0.749   0.713   0.818   0.447   0.344   0.478   0.414   0.312   0.445
154   V         0.171   0.251   0.195  -0.113   0.011  -0.062  -0.098   0.006  -0.052
155   L         0.955   1.124   1.061   0.777   1.047   0.933   0.824   1.125   0.958
156   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
157   G         0.341   0.335   0.247   0.531   0.509   0.329   0.209   0.198   0.047
158   T         1.303   1.179   1.118   1.545   1.400   1.322   1.439   1.224   1.072
159   S        -0.364  -0.314  -0.361  -0.596  -0.532  -0.561  -0.508  -0.457  -0.470
160   L         1.303   1.179   1.118   1.341   1.191   1.132   1.439   1.224   1.072
161   T         1.974   2.009   2.127   2.123   2.186   2.381   2.259   2.314   2.531
162   A         1.974   2.009   2.127   1.993   2.044   2.252   2.259   2.314   2.531
163   Y         0.341   0.398   0.272   0.597   0.692   0.521   0.209   0.306   0.087
164   F         0.658   0.514   0.347   1.046   0.871   0.673   0.722   0.496   0.216
165   I         0.955   0.979   0.976   0.756   0.787   0.764   0.824   0.853   0.785
166   F        -0.956  -0.922  -0.863  -1.072  -0.992  -0.896  -0.918  -0.864  -0.773
167   F        -1.068  -1.198  -1.210  -0.662  -0.878  -0.889  -0.816  -0.942  -0.921
168   T        -1.253  -1.298  -1.224  -1.168  -1.198  -1.086  -1.021  -1.045  -0.937
169   Y        -0.475  -0.471  -0.439  -0.654  -0.672  -0.611  -0.611  -0.623  -0.553
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   A         0.955   0.979   0.976   0.758   0.786   0.766   0.824   0.853   0.785
172   Q        -1.253  -1.260  -1.212  -1.181  -1.224  -1.146  -1.021  -1.019  -0.929
173   L         0.045  -0.133  -0.282   0.134  -0.123  -0.377   0.107  -0.135  -0.340
174   Q         0.955   0.979   0.976   0.847   0.883   0.881   0.824   0.853   0.785
175   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   Y        -0.772  -0.896  -0.863  -0.744  -0.918  -0.854  -0.713  -0.835  -0.773
186   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
187   K        -1.068  -1.025  -0.910  -1.048  -1.010  -0.827  -1.021  -0.964  -0.820
188   V         0.341   0.439   0.249   0.402   0.557   0.205   0.209   0.349   0.039
189   Y        -0.364  -0.337  -0.373  -0.525  -0.478  -0.483  -0.508  -0.469  -0.478
190   L        -0.548  -0.564  -0.451  -0.718  -0.726  -0.535  -0.713  -0.710  -0.568
191   I         0.652   0.687   0.810   0.238   0.295   0.475   0.209   0.257   0.429
192   S         1.974   2.009   2.127   1.989   2.058   2.248   2.259   2.314   2.531
193   G         0.749   0.767   0.844   0.451   0.457   0.549   0.414   0.426   0.503
194   A         1.974   2.009   2.127   1.993   2.044   2.252   2.259   2.314   2.531
195   A         0.652   0.678   0.807   0.305   0.343   0.538   0.209   0.238   0.420
196   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
197   A         1.974   2.009   2.127   1.993   2.044   2.252   2.259   2.314   2.531
198   V         0.749   0.730   0.827   0.585   0.521   0.634   0.414   0.348   0.466
199   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
200   T         0.658   0.536   0.363   0.844   0.704   0.461   0.722   0.529   0.242
201   V         0.171   0.251   0.195   0.047   0.156   0.103  -0.098   0.006  -0.052
202   C        -0.067  -0.018   0.071  -0.155  -0.115  -0.003  -0.406  -0.348  -0.232
203   I         0.059   0.011   0.091  -0.281  -0.396  -0.305  -0.201  -0.288  -0.198
204   Q         1.974   2.009   2.127   2.227   2.278   2.486   2.259   2.314   2.531
205   L         0.749   0.723   0.820   0.468   0.387   0.514   0.414   0.333   0.450
206   A         1.974   2.009   2.127   1.993   2.044   2.252   2.259   2.314   2.531
207   L         0.341   0.315   0.240   0.218   0.187   0.079   0.209   0.171   0.036
208   N         0.135   0.032   0.128   0.322   0.140   0.257  -0.113  -0.258  -0.149
209   V        -0.901  -0.937  -0.874  -0.930  -0.955  -0.866  -0.854  -0.879  -0.785
210   F        -1.027  -1.034  -0.918  -1.159  -1.134  -0.970  -0.984  -0.972  -0.828
211   K         0.242   0.197   0.171  -0.028  -0.115  -0.175   0.054  -0.016  -0.075
212   A         0.955   0.877   0.896   0.849   0.686   0.669   0.824   0.652   0.616
213   S        -0.772  -0.804  -0.803  -0.812  -0.904  -0.906  -0.713  -0.753  -0.716
214   K         0.658   0.492   0.341   0.771   0.574   0.394   0.722   0.465   0.205
215   V         1.974   2.009   2.127   1.892   1.952   2.150   2.259   2.314   2.531
216   I         0.749   0.740   0.824   0.458   0.419   0.510   0.414   0.369   0.458
217   A         0.955   0.979   0.976   0.758   0.786   0.766   0.824   0.853   0.785
218   I         0.658   0.492   0.341   0.808   0.589   0.352   0.722   0.465   0.205
219   A         0.117   0.065   0.151  -0.156  -0.210  -0.088  -0.201  -0.241  -0.122
220   G         1.303   1.427   1.157   1.262   1.421   1.080   1.439   1.633   1.149
221   G         0.749   0.767   0.844   0.447   0.470   0.545   0.414   0.426   0.503
222   P        -0.956  -0.866  -0.844  -0.982  -0.840  -0.834  -0.918  -0.811  -0.762
223   E         0.658   0.743   0.407   0.879   1.002   0.509   0.722   0.840   0.312
224   K         1.974   2.009   2.127   1.884   1.941   2.143   2.259   2.314   2.531
225   V         0.341   0.234   0.226   0.622   0.467   0.411   0.209   0.056   0.013
226   A        -0.533  -0.542  -0.717  -0.371  -0.386  -0.619  -0.406  -0.415  -0.609
227   F         0.171   0.079   0.151   0.348   0.205   0.295  -0.098  -0.216  -0.124
228   V         0.045  -0.133  -0.282   0.144  -0.088  -0.335   0.107  -0.135  -0.340
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   E         0.658   0.514   0.347   0.856   0.651   0.357   0.722   0.496   0.216
231   S        -0.237  -0.319  -0.363  -0.230  -0.350  -0.453  -0.303  -0.418  -0.458
232   F        -0.237  -0.369  -0.370  -0.296  -0.505  -0.532  -0.303  -0.463  -0.461
233   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
234   D        -0.533  -0.655  -0.772  -0.294  -0.470  -0.655  -0.406  -0.551  -0.672
235   N         0.658   0.676   0.374   0.937   0.972   0.573   0.722   0.746   0.260
236   V         0.045   0.030  -0.235   0.085   0.060  -0.372   0.107   0.074  -0.277
237   V        -0.067  -0.070   0.048  -0.174  -0.242  -0.082  -0.406  -0.415  -0.263
238   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   V         0.341   0.197   0.192   0.209  -0.006  -0.043   0.209  -0.008  -0.047
240   D         0.749   0.767   0.844   0.689   0.707   0.802   0.414   0.426   0.503
241   Y         1.974   2.009   2.127   2.187   2.238   2.445   2.259   2.314   2.531
242   K         0.955   1.124   1.061   0.871   1.114   1.045   0.824   1.125   0.958
243   D         0.045  -0.043  -0.245   0.294   0.153  -0.169   0.107  -0.021  -0.289
244   P        -0.772  -0.717  -0.787  -0.581  -0.510  -0.636  -0.713  -0.650  -0.699
245   S        -0.548  -0.476  -0.450  -0.665  -0.562  -0.506  -0.713  -0.631  -0.569
246   F        -0.364  -0.349  -0.370  -0.164  -0.131  -0.111  -0.508  -0.465  -0.468
247   K        -0.364  -0.423  -0.372  -0.366  -0.432  -0.325  -0.508  -0.545  -0.470
248   Q        -0.475  -0.453  -0.429  -0.546  -0.503  -0.441  -0.611  -0.571  -0.542
249   K        -0.772  -0.877  -0.852  -0.575  -0.786  -0.775  -0.713  -0.822  -0.766
250   L        -0.237  -0.166  -0.333  -0.291  -0.208  -0.458  -0.303  -0.233  -0.419
251   I        -1.253  -1.282  -1.232  -1.306  -1.359  -1.301  -1.021  -1.039  -0.945
252   E        -0.548  -0.567  -0.448  -0.667  -0.652  -0.508  -0.713  -0.711  -0.565
253   A        -0.772  -0.691  -0.785  -0.734  -0.621  -0.739  -0.713  -0.607  -0.687
254   A        -1.068  -1.058  -0.916  -1.171  -1.100  -0.906  -1.021  -0.993  -0.826
255   G         1.107   1.121   0.989   1.031   1.056   0.827   1.106   1.120   0.811
256   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   E        -1.253  -1.240  -1.223  -1.021  -1.014  -0.977  -1.021  -1.003  -0.938
259   N        -0.956  -0.996  -0.887  -0.984  -1.060  -0.926  -0.918  -0.938  -0.799
260   T        -0.067  -0.051   0.075  -0.278  -0.289  -0.101  -0.406  -0.390  -0.226
261   V         0.749   0.760   0.842   0.414   0.424   0.528   0.414   0.412   0.499
262   D         1.974   2.009   2.127   2.077   2.136   2.335   2.259   2.314   2.531
263   Y        -0.237  -0.288  -0.344  -0.252  -0.334  -0.401  -0.303  -0.372  -0.428
264   F         0.955   0.979   0.976   1.118   1.148   1.133   0.824   0.853   0.785
265   I        -0.067  -0.008   0.096  -0.144  -0.054   0.095  -0.406  -0.318  -0.191
266   D         1.303   1.179   1.118   1.487   1.337   1.250   1.439   1.224   1.072
267   N         1.303   1.386   1.151   1.587   1.696   1.435   1.439   1.568   1.136
268   V         1.974   2.009   2.127   1.892   1.952   2.150   2.259   2.314   2.531
269   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
270   S         1.303   1.325   1.146   1.262   1.297   1.062   1.439   1.471   1.126
271   N         0.658   0.729   0.405   0.916   1.019   0.576   0.722   0.823   0.309
272   V         0.045  -0.113  -0.258   0.242   0.031  -0.203   0.107  -0.109  -0.307
273   L         1.303   1.179   1.118   1.348   1.201   1.147   1.439   1.224   1.072
274   E        -0.364  -0.385  -0.383  -0.413  -0.422  -0.396  -0.508  -0.528  -0.492
275   A         0.059  -0.011   0.070   0.113  -0.033   0.077  -0.201  -0.320  -0.228
276   G        -1.365  -1.299  -1.234  -1.414  -1.369  -1.296  -1.123  -1.054  -0.947
277   V         0.658   0.676   0.374   0.718   0.745   0.306   0.722   0.746   0.260
278   L        -1.365  -1.372  -1.245  -1.319  -1.313  -1.134  -1.123  -1.108  -0.955
279   L        -0.772  -0.896  -0.863  -0.837  -1.010  -0.942  -0.713  -0.835  -0.773
280   L        -0.660  -0.653  -0.508  -0.921  -0.896  -0.664  -0.816  -0.804  -0.629
281   K         0.652   0.676   0.807   0.322   0.371   0.582   0.209   0.232   0.422
282   Q        -1.661  -1.651  -1.536  -1.499  -1.520  -1.310  -1.226  -1.203  -1.057
283   R        -0.533  -0.672  -0.777  -0.092  -0.299  -0.445  -0.406  -0.570  -0.676
284   A         0.652   0.678   0.807   0.202   0.232   0.444   0.209   0.238   0.420
285   M        -0.956  -0.847  -0.852  -0.578  -0.412  -0.409  -0.918  -0.782  -0.766
286   L        -0.548  -0.525  -0.436  -0.814  -0.760  -0.630  -0.713  -0.680  -0.551
287   I         0.117   0.197   0.165  -0.214  -0.085  -0.109  -0.201  -0.097  -0.108
288   A         0.341   0.197   0.192   0.427   0.223   0.230   0.209  -0.008  -0.047
289   C         1.974   2.009   2.127   2.324   2.380   2.583   2.259   2.314   2.531
290   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
291   A         0.059   0.073   0.102  -0.184  -0.183  -0.184  -0.201  -0.190  -0.178
292   I         1.974   2.009   2.127   1.988   2.048   2.246   2.259   2.314   2.531
293   S         0.955   1.098   0.982   0.882   1.120   0.898   0.824   1.077   0.797
294   A         0.171   0.152   0.156  -0.004  -0.029   0.014  -0.098  -0.148  -0.121
295   Y         1.974   2.009   2.127   2.187   2.238   2.445   2.259   2.314   2.531
296   N         1.974   2.009   2.127   2.146   2.202   2.405   2.259   2.314   2.531
297   D        -0.237  -0.322  -0.364  -0.132  -0.274  -0.366  -0.303  -0.418  -0.463
298   P        -1.549  -1.386  -1.489  -1.181  -0.943  -1.137  -1.123  -0.971  -1.018
299   S        -0.956  -1.019  -0.895  -0.979  -1.045  -0.871  -0.918  -0.960  -0.807
300   K         0.059   0.059   0.106  -0.166  -0.174  -0.107  -0.201  -0.217  -0.173
301   F        -1.365  -1.330  -1.235  -1.252  -1.172  -1.079  -1.123  -1.081  -0.949
302   V        -1.957  -1.874  -1.799  -1.748  -1.630  -1.561  -1.328  -1.258  -1.140
303   F        -0.237  -0.283  -0.360  -0.270  -0.333  -0.449  -0.303  -0.357  -0.448
304   K        -0.364  -0.264  -0.348  -0.479  -0.322  -0.425  -0.508  -0.363  -0.442
305   G         0.059   0.213   0.144  -0.041   0.230   0.033  -0.201   0.031  -0.112
306   Y        -0.772  -0.896  -0.863  -0.454  -0.687  -0.699  -0.713  -0.835  -0.773
307   S        -1.661  -1.606  -1.526  -1.681  -1.642  -1.526  -1.226  -1.169  -1.051
308   F        -1.253  -1.329  -1.226  -0.952  -1.033  -0.889  -1.021  -1.072  -0.940
309   I         0.652   0.677   0.809   0.238   0.261   0.463   0.209   0.234   0.425
310   L        -0.660  -0.627  -0.502  -0.979  -0.954  -0.771  -0.816  -0.776  -0.622
311   T        -0.237  -0.210  -0.325  -0.085  -0.086  -0.234  -0.303  -0.292  -0.413
312   K         0.117   0.133   0.163  -0.047  -0.024   0.065  -0.201  -0.159  -0.104
313   R         0.749   0.760   0.842   0.745   0.748   0.837   0.414   0.412   0.499
314   L         0.955   0.933   0.923   0.804   0.757   0.709   0.824   0.763   0.674
315   V        -0.533  -0.544  -0.719  -0.211  -0.225  -0.530  -0.406  -0.417  -0.612
316   V        -0.067  -0.069   0.063  -0.348  -0.340  -0.140  -0.406  -0.413  -0.243
317   K        -0.548  -0.530  -0.438  -0.491  -0.466  -0.325  -0.713  -0.676  -0.550
318   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
319   V         0.658   0.676   0.374   0.928   0.955   0.478   0.722   0.746   0.260
320   L         0.955   0.979   0.976   0.857   0.894   0.853   0.824   0.853   0.785
321   V         0.341   0.491   0.335   0.193   0.444   0.183   0.209   0.455   0.195
322   T        -1.957  -1.901  -1.800  -1.689  -1.604  -1.491  -1.328  -1.277  -1.141
323   D         0.955   0.918   0.907   1.010   0.950   0.902   0.824   0.735   0.639
324   N        -0.956  -1.012  -0.891  -0.741  -0.828  -0.630  -0.918  -0.955  -0.804
325   I        -1.661  -1.597  -1.519  -1.825  -1.767  -1.643  -1.226  -1.166  -1.046
326   D        -0.956  -0.910  -0.843  -1.011  -0.897  -0.816  -0.918  -0.854  -0.756
327   D        -1.253  -1.257  -1.209  -0.879  -0.885  -0.783  -1.021  -1.017  -0.926
328   F         0.749   0.747   0.826   0.743   0.721   0.832   0.414   0.385   0.463
329   P         0.341   0.357   0.296   0.521   0.576   0.477   0.209   0.258   0.131
330   K        -0.772  -0.682  -0.774  -0.680  -0.554  -0.697  -0.713  -0.613  -0.685
331   A        -0.364  -0.420  -0.366  -0.544  -0.584  -0.502  -0.508  -0.547  -0.468
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   L        -0.772  -0.779  -0.807  -0.778  -0.803  -0.853  -0.713  -0.731  -0.721
334   D        -1.253  -1.251  -1.193  -1.377  -1.382  -1.284  -1.021  -1.011  -0.912
335   K        -1.365  -1.388  -1.265  -1.432  -1.441  -1.249  -1.123  -1.120  -0.971
336   L         0.341   0.357   0.296   0.275   0.341   0.248   0.209   0.258   0.131
337   G        -1.365  -1.341  -1.237  -1.564  -1.506  -1.356  -1.123  -1.087  -0.949
338   S        -1.549  -1.573  -1.524  -1.518  -1.582  -1.501  -1.123  -1.136  -1.046
339   L        -0.364  -0.382  -0.382  -0.432  -0.469  -0.390  -0.508  -0.525  -0.490
340   V         0.171   0.182   0.189  -0.092  -0.054  -0.076  -0.098  -0.067  -0.067
341   K        -0.237  -0.316  -0.369  -0.344  -0.495  -0.568  -0.303  -0.426  -0.470
342   H        -0.533  -0.501  -0.720  -0.186  -0.132  -0.460  -0.406  -0.365  -0.612
343   G         1.303   1.332   1.146   1.282   1.324   1.105   1.439   1.481   1.126
344   K         1.303   1.332   1.146   1.314   1.361   1.147   1.439   1.481   1.126
345   I         0.749   0.752   0.831   0.468   0.452   0.541   0.414   0.395   0.475
346   D        -0.237  -0.099  -0.288  -0.246  -0.071  -0.283  -0.303  -0.139  -0.355
347   L        -1.661  -1.663  -1.547  -1.570  -1.550  -1.398  -1.226  -1.209  -1.064
348   L        -1.253  -1.109  -1.181  -1.243  -1.039  -1.147  -1.021  -0.862  -0.896
349   K        -0.956  -0.996  -0.887  -1.045  -1.062  -0.908  -0.918  -0.938  -0.799
350   S        -1.253  -1.219  -1.193  -1.154  -1.096  -1.069  -1.021  -0.987  -0.913
351   A        -1.661  -1.610  -1.533  -1.595  -1.563  -1.451  -1.226  -1.173  -1.055
352   T        -1.365  -1.388  -1.265  -1.185  -1.202  -1.050  -1.123  -1.120  -0.971
353   L        -1.068  -1.198  -1.210  -0.982  -1.191  -1.224  -0.816  -0.942  -0.921
354   E        -0.108  -0.096   0.043  -0.523  -0.517  -0.309  -0.465  -0.450  -0.270
355   D         0.305   0.332   0.173   0.369   0.404   0.099   0.184   0.219  -0.064
356   G         0.305   0.222   0.138   0.198   0.041  -0.146   0.184   0.046  -0.121
357   T         0.028   0.084   0.107  -0.068   0.026   0.061  -0.278  -0.199  -0.178
358   G         0.305   0.489   0.199   0.139   0.431  -0.103   0.184   0.463  -0.023
359   D         0.028   0.050   0.093  -0.017   0.003   0.093  -0.278  -0.258  -0.202
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   K        -1.068  -1.015  -0.908  -1.283  -1.226  -1.035  -1.021  -0.956  -0.818
365   F         0.059   0.047   0.101  -0.187  -0.229  -0.171  -0.201  -0.230  -0.181
366   K        -1.253  -1.285  -1.222  -1.140  -1.178  -1.087  -1.021  -1.039  -0.937
367   N        -1.365  -1.390  -1.232  -1.481  -1.513  -1.288  -1.123  -1.122  -0.945
368   V        -0.548  -0.555  -0.456  -0.891  -0.902  -0.757  -0.713  -0.713  -0.576
369   P         1.303   1.277   1.131   1.584   1.550   1.366   1.439   1.392   1.098
370   L        -0.772  -0.699  -0.796  -0.681  -0.582  -0.717  -0.713  -0.634  -0.702
371   I        -0.475  -0.460  -0.414  -0.625  -0.625  -0.574  -0.611  -0.590  -0.521
372   W         0.045  -0.133  -0.282   0.583   0.334   0.081   0.107  -0.135  -0.340
373   K        -1.253  -1.216  -1.194  -1.291  -1.270  -1.283  -1.021  -0.988  -0.914
374   G        -1.365  -1.291  -1.226  -1.491  -1.387  -1.259  -1.123  -1.049  -0.940
375   L         1.303   1.179   1.118   1.348   1.201   1.147   1.439   1.224   1.072
376   F         0.658   0.492   0.341   0.970   0.734   0.504   0.722   0.465   0.205
377   S        -0.772  -0.768  -0.793  -0.716  -0.689  -0.794  -0.713  -0.705  -0.705
378   G        -0.237   0.019  -0.284  -0.318   0.034  -0.377  -0.303   0.025  -0.350
379   V        -1.253  -1.283  -1.213  -1.212  -1.309  -1.223  -1.021  -1.037  -0.929
380   N         0.652   0.741   0.852   0.364   0.555   0.714   0.209   0.371   0.520
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   K        -0.772  -0.896  -0.863  -0.675  -0.887  -0.872  -0.713  -0.835  -0.773
383   G         1.974   2.009   2.127   1.864   1.915   2.122   2.259   2.314   2.531
384   K         1.974   2.009   2.127   1.884   1.941   2.143   2.259   2.314   2.531
385   L         0.341   0.249   0.212   0.346   0.223   0.182   0.209   0.080  -0.019
386   I         0.341   0.446   0.258   0.260   0.406   0.083   0.209   0.344   0.055
387   T        -0.237  -0.351  -0.367  -0.115  -0.295  -0.360  -0.303  -0.442  -0.464
388   K         1.303   1.277   1.131   1.294   1.274   1.083   1.439   1.392   1.098
389   V        -0.067  -0.042   0.062  -0.500  -0.464  -0.323  -0.406  -0.373  -0.240
390   N        -0.475  -0.466  -0.440  -0.626  -0.628  -0.595  -0.611  -0.598  -0.556
391   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   E        -0.589  -0.523  -0.451  -0.648  -0.543  -0.460  -0.730  -0.647  -0.559
400   E        -0.056  -0.013   0.086  -0.390  -0.317  -0.171  -0.398  -0.340  -0.211
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03102
Output conservation file - output/Q03102
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
