1     M         1.803   1.811   1.828   1.973   1.982   2.013   1.940   1.949   1.971
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    L        -1.194  -1.187  -1.173  -1.133  -1.113  -1.096  -1.025  -1.013  -0.987
57    K         0.067   0.021   0.015  -0.116  -0.204  -0.214  -0.037  -0.109  -0.119
58    E        -1.194  -1.187  -1.173  -1.246  -1.224  -1.209  -1.025  -1.013  -0.987
59    E        -1.194  -1.187  -1.173  -1.262  -1.240  -1.224  -1.025  -1.013  -0.987
60    Y        -1.194  -1.187  -1.173  -1.034  -1.035  -0.997  -1.025  -1.013  -0.987
61    N         0.067   0.094   0.036   0.141   0.188   0.087  -0.037   0.007  -0.084
62    L        -1.194  -1.187  -1.173  -1.210  -1.190  -1.172  -1.025  -1.013  -0.987
63    S        -1.194  -1.187  -1.173  -1.267  -1.248  -1.229  -1.025  -1.013  -0.987
64    G        -1.194  -1.187  -1.173  -1.230  -1.218  -1.193  -1.025  -1.013  -0.987
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    A         0.067   0.094   0.036  -0.104  -0.061  -0.148  -0.037   0.007  -0.084
69    D        -1.194  -1.187  -1.173  -1.159  -1.153  -1.121  -1.025  -1.013  -0.987
70    N         0.067   0.021   0.015   0.003  -0.083  -0.093  -0.037  -0.109  -0.119
71    M        -1.194  -1.187  -1.173  -1.000  -0.995  -0.963  -1.025  -1.013  -0.987
72    A         0.067   0.021   0.015   0.174   0.099   0.096  -0.037  -0.109  -0.119
73    S         0.067   0.094   0.036  -0.047   0.007  -0.106  -0.037   0.007  -0.084
74    A        -1.194  -1.187  -1.173  -1.118  -1.094  -1.081  -1.025  -1.013  -0.987
75    E        -1.194  -1.187  -1.173  -1.149  -1.149  -1.111  -1.025  -1.013  -0.987
76    L         0.067   0.021   0.015  -0.104  -0.175  -0.181  -0.037  -0.109  -0.119
77    S         0.067   0.094   0.036  -0.008   0.046  -0.069  -0.037   0.007  -0.084
78    F        -0.088  -0.084  -0.065  -0.058  -0.053  -0.020  -0.284  -0.277  -0.247
79    K        -0.088  -0.084  -0.065  -0.205  -0.200  -0.167  -0.284  -0.277  -0.247
80    K         1.803   1.811   1.828   1.704   1.715   1.744   1.940   1.949   1.971
81    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    L         1.803   1.811   1.828   1.614   1.627   1.653   1.940   1.949   1.971
86    K        -1.194  -1.187  -1.173  -1.319  -1.315  -1.282  -1.025  -1.013  -0.987
87    K         0.067   0.021   0.015   0.010  -0.065  -0.066  -0.037  -0.109  -0.119
88    F         1.803   1.811   1.828   1.893   1.905   1.933   1.940   1.949   1.971
89    M         0.067   0.106   0.043   0.115   0.186   0.063  -0.037   0.025  -0.074
90    I         0.067   0.021   0.015  -0.012  -0.093  -0.117  -0.037  -0.109  -0.119
91    A        -1.194  -1.187  -1.173  -1.029  -1.036  -0.992  -1.025  -1.013  -0.987
92    Q        -1.194  -1.187  -1.173  -1.164  -1.157  -1.126  -1.025  -1.013  -0.987
93    V         0.067   0.094   0.036   0.152   0.196   0.101  -0.037   0.007  -0.084
94    T        -1.194  -1.187  -1.173  -1.164  -1.132  -1.126  -1.025  -1.013  -0.987
95    K         0.067   0.021   0.015  -0.012  -0.092  -0.093  -0.037  -0.109  -0.119
96    G         0.067   0.106   0.043   0.067   0.140   0.017  -0.037   0.025  -0.074
97    I        -1.194  -1.187  -1.173  -1.069  -1.056  -1.031  -1.025  -1.013  -0.987
98    M         0.067   0.094   0.036  -0.050  -0.010  -0.088  -0.037   0.007  -0.084
99    Q        -1.194  -1.187  -1.173  -1.054  -1.044  -1.016  -1.025  -1.013  -0.987
100   R         0.067   0.094   0.036  -0.047  -0.006  -0.096  -0.037   0.007  -0.084
101   Y         1.803   1.811   1.828   1.973   1.983   2.013   1.940   1.949   1.971
102   A         0.067   0.094   0.036  -0.081  -0.036  -0.125  -0.037   0.007  -0.084
103   S        -1.194  -1.187  -1.173  -1.395  -1.367  -1.358  -1.025  -1.013  -0.987
104   L         1.803   1.811   1.828   1.614   1.627   1.653   1.940   1.949   1.971
105   L         0.067   0.021   0.015  -0.089  -0.156  -0.163  -0.037  -0.109  -0.119
106   V         0.067   0.106   0.043   0.134   0.192   0.096  -0.037   0.025  -0.074
107   T         0.067   0.094   0.036   0.225   0.275   0.165  -0.037   0.007  -0.084
108   M        -1.194  -1.187  -1.173  -1.118  -1.103  -1.081  -1.025  -1.013  -0.987
109   P         0.067   0.021   0.015   0.261   0.184   0.165  -0.037  -0.109  -0.119
110   S        -1.194  -1.187  -1.173  -1.064  -1.046  -1.026  -1.025  -1.013  -0.987
111   D         0.067   0.106   0.043   0.188   0.255   0.151  -0.037   0.025  -0.074
112   D        -1.194  -1.187  -1.173  -1.194  -1.189  -1.157  -1.025  -1.013  -0.987
113   D         0.067   0.021   0.015   0.100   0.015   0.001  -0.037  -0.109  -0.119
114   N        -1.194  -1.187  -1.173  -1.225  -1.204  -1.188  -1.025  -1.013  -0.987
115   A         0.067   0.021   0.015   0.145   0.068   0.062  -0.037  -0.109  -0.119
116   I        -0.088  -0.084  -0.065  -0.229  -0.224  -0.191  -0.284  -0.277  -0.247
117   I        -0.088  -0.084  -0.065  -0.229  -0.224  -0.191  -0.284  -0.277  -0.247
118   G        -0.088  -0.084  -0.065  -0.158  -0.153  -0.120  -0.284  -0.277  -0.247
119   T         1.803   1.811   1.828   1.759   1.769   1.798   1.940   1.949   1.971
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   N         1.803   1.811   1.828   1.887   1.899   1.927   1.940   1.949   1.971
127   H        -0.088  -0.084  -0.065  -0.174  -0.161  -0.136  -0.284  -0.277  -0.247
128   L        -0.088  -0.084  -0.065  -0.309  -0.296  -0.271  -0.284  -0.277  -0.247
129   K        -1.194  -1.187  -1.173  -1.251  -1.224  -1.214  -1.025  -1.013  -0.987
130   T         0.067   0.094   0.036  -0.159  -0.114  -0.209  -0.037   0.007  -0.084
131   T        -1.194  -1.187  -1.173  -0.947  -0.937  -0.910  -1.025  -1.013  -0.987
132   K         0.067   0.106   0.043  -0.047   0.013  -0.086  -0.037   0.025  -0.074
133   F         0.067   0.106   0.043   0.141   0.209   0.100  -0.037   0.025  -0.074
134   L        -1.194  -1.187  -1.173  -1.184  -1.168  -1.147  -1.025  -1.013  -0.987
135   E         0.067   0.021   0.015   0.026  -0.058  -0.071  -0.037  -0.109  -0.119
136   I         0.067   0.106   0.043   0.122   0.191   0.086  -0.037   0.025  -0.074
137   I         0.067   0.021   0.015  -0.012  -0.093  -0.117  -0.037  -0.109  -0.119
138   L         1.803   1.811   1.828   1.614   1.627   1.653   1.940   1.949   1.971
139   H        -1.194  -1.187  -1.173  -1.024  -1.020  -0.987  -1.025  -1.013  -0.987
140   R         1.803   1.811   1.828   1.788   1.803   1.828   1.940   1.949   1.971
141   A         0.067   0.094   0.036   0.122   0.163   0.073  -0.037   0.007  -0.084
142   K         0.067   0.106   0.043  -0.047   0.013  -0.086  -0.037   0.025  -0.074
143   S        -1.194  -1.187  -1.173  -1.159  -1.143  -1.121  -1.025  -1.013  -0.987
144   S        -1.194  -1.187  -1.173  -1.298  -1.286  -1.261  -1.025  -1.013  -0.987
145   H         0.067   0.094   0.036   0.141   0.185   0.103  -0.037   0.007  -0.084
146   L        -1.194  -1.187  -1.173  -1.088  -1.061  -1.051  -1.025  -1.013  -0.987
147   Q         1.803   1.811   1.828   1.885   1.892   1.925   1.940   1.949   1.971
148   F         1.803   1.811   1.828   1.893   1.905   1.933   1.940   1.949   1.971
149   K         1.803   1.811   1.828   1.714   1.719   1.753   1.940   1.949   1.971
150   K         1.803   1.811   1.828   1.714   1.719   1.753   1.940   1.949   1.971
151   V         0.067   0.021   0.015   0.174   0.098   0.096  -0.037  -0.109  -0.119
152   C         1.803   1.811   1.828   2.037   2.049   2.076   1.940   1.949   1.971
153   C         0.067   0.021   0.015   0.271   0.193   0.176  -0.037  -0.109  -0.119
154   I         0.067   0.021   0.015  -0.012  -0.093  -0.117  -0.037  -0.109  -0.119
155   V        -1.194  -1.187  -1.173  -1.205  -1.199  -1.167  -1.025  -1.013  -0.987
156   I         1.803   1.811   1.828   1.837   1.856   1.876   1.940   1.949   1.971
157   K         1.803   1.811   1.828   1.714   1.719   1.753   1.940   1.949   1.971
158   F         1.803   1.811   1.828   1.893   1.905   1.933   1.940   1.949   1.971
159   L         0.067   0.021   0.015  -0.089  -0.156  -0.163  -0.037  -0.109  -0.119
160   D         0.067   0.094   0.036   0.115   0.164   0.069  -0.037   0.007  -0.084
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   C         1.803   1.811   1.828   2.037   2.049   2.076   1.940   1.949   1.971
163   C         0.067   0.021   0.015   0.282   0.200   0.189  -0.037  -0.109  -0.119
164   S        -1.194  -1.187  -1.173  -1.164  -1.162  -1.126  -1.025  -1.013  -0.987
165   K        -1.194  -1.187  -1.173  -1.319  -1.315  -1.282  -1.025  -1.013  -0.987
166   E         0.067   0.021   0.015   0.059  -0.015  -0.032  -0.037  -0.109  -0.119
167   T        -1.194  -1.187  -1.173  -1.074  -1.065  -1.036  -1.025  -1.013  -0.987
168   N         1.803   1.811   1.828   1.804   1.816   1.844   1.940   1.949   1.971
169   Y         1.803   1.811   1.828   1.973   1.983   2.013   1.940   1.949   1.971
170   M         1.803   1.811   1.828   1.973   1.982   2.013   1.940   1.949   1.971
171   K         0.067   0.106   0.043  -0.001   0.052  -0.035  -0.037   0.025  -0.074
172   F         0.067   0.021   0.015   0.203   0.130   0.124  -0.037  -0.109  -0.119
173   L         1.803   1.811   1.828   1.614   1.627   1.653   1.940   1.949   1.971
174   K         1.803   1.811   1.828   1.714   1.719   1.753   1.940   1.949   1.971
175   F        -1.194  -1.187  -1.173  -0.858  -0.847  -0.820  -1.025  -1.013  -0.987
176   S         0.067   0.094   0.036   0.067   0.121   0.004  -0.037   0.007  -0.084
177   L         0.067   0.021   0.015  -0.104  -0.175  -0.181  -0.037  -0.109  -0.119
178   H        -1.194  -1.187  -1.173  -1.074  -1.065  -1.036  -1.025  -1.013  -0.987
179   K         0.067   0.106   0.043  -0.047   0.013  -0.086  -0.037   0.025  -0.074
180   L         0.067   0.021   0.015  -0.104  -0.175  -0.181  -0.037  -0.109  -0.119
181   F        -1.194  -1.187  -1.173  -1.184  -1.165  -1.147  -1.025  -1.013  -0.987
182   V         1.803   1.811   1.828   1.861   1.870   1.901   1.940   1.949   1.971
183   A         0.067   0.106   0.043   0.071   0.133   0.026  -0.037   0.025  -0.074
184   A         0.067   0.021   0.015   0.203   0.133   0.130  -0.037  -0.109  -0.119
185   F         0.067   0.021   0.015   0.041  -0.048  -0.066  -0.037  -0.109  -0.119
186   I        -1.194  -1.187  -1.173  -1.069  -1.056  -1.031  -1.025  -1.013  -0.987
187   L         1.803   1.811   1.828   1.614   1.627   1.653   1.940   1.949   1.971
188   S         0.067   0.021   0.015  -0.136  -0.211  -0.222  -0.037  -0.109  -0.119
189   V         0.067   0.021   0.015   0.174   0.099   0.096  -0.037  -0.109  -0.119
190   P         1.803   1.811   1.828   2.029   2.045   2.069   1.940   1.949   1.971
191   N         1.803   1.811   1.828   1.821   1.833   1.861   1.940   1.949   1.971
192   V        -0.088  -0.084  -0.065  -0.152  -0.145  -0.113  -0.284  -0.277  -0.247
193   V        -0.088  -0.084  -0.065  -0.080  -0.073  -0.041  -0.284  -0.277  -0.247
194   G        -0.088  -0.084  -0.065  -0.144  -0.137  -0.105  -0.284  -0.277  -0.247
195   D         1.803   1.811   1.828   1.888   1.900   1.928   1.940   1.949   1.971
196   D        -1.194  -1.187  -1.173  -1.029  -1.015  -0.992  -1.025  -1.013  -0.987
197   R        -1.194  -1.187  -1.173  -1.069  -1.052  -1.031  -1.025  -1.013  -0.987
198   D        -1.194  -1.187  -1.173  -0.933  -0.907  -0.895  -1.025  -1.013  -0.987
199   R         0.067   0.021   0.015   0.003  -0.077  -0.090  -0.037  -0.109  -0.119
200   I        -1.194  -1.187  -1.173  -1.133  -1.103  -1.096  -1.025  -1.013  -0.987
201   T        -1.194  -1.187  -1.173  -1.138  -1.123  -1.101  -1.025  -1.013  -0.987
202   T        -1.194  -1.187  -1.173  -1.174  -1.160  -1.136  -1.025  -1.013  -0.987
203   R         0.067   0.021   0.015   0.003  -0.077  -0.090  -0.037  -0.109  -0.119
204   D         0.067   0.021   0.015   0.152   0.078   0.061  -0.037  -0.109  -0.119
205   E         0.067   0.094   0.036  -0.028   0.012  -0.075  -0.037   0.007  -0.084
206   T        -1.194  -1.187  -1.173  -1.277  -1.269  -1.240  -1.025  -1.013  -0.987
207   Y         0.067   0.021   0.015   0.275   0.198   0.193  -0.037  -0.109  -0.119
208   H        -1.194  -1.187  -1.173  -1.159  -1.160  -1.121  -1.025  -1.013  -0.987
209   L         0.067   0.106   0.043  -0.020   0.037  -0.045  -0.037   0.025  -0.074
210   Y         0.067   0.021   0.015   0.225   0.142   0.134  -0.037  -0.109  -0.119
211   S         1.803   1.811   1.828   1.639   1.654   1.678   1.940   1.949   1.971
212   Q        -1.194  -1.187  -1.173  -1.210  -1.209  -1.172  -1.025  -1.013  -0.987
213   I        -1.194  -1.187  -1.173  -1.069  -1.056  -1.031  -1.025  -1.013  -0.987
214   T         0.067   0.021   0.015   0.018  -0.061  -0.064  -0.037  -0.109  -0.119
215   G         1.803   1.811   1.828   1.909   1.922   1.949   1.940   1.949   1.971
216   L         0.067   0.021   0.015  -0.104  -0.175  -0.181  -0.037  -0.109  -0.119
217   P        -1.194  -1.187  -1.173  -1.174  -1.171  -1.136  -1.025  -1.013  -0.987
218   L        -1.194  -1.187  -1.173  -1.262  -1.242  -1.224  -1.025  -1.013  -0.987
219   E         1.803   1.811   1.828   1.829   1.844   1.868   1.940   1.949   1.971
220   E         0.067   0.021   0.015   0.104   0.030   0.021  -0.037  -0.109  -0.119
221   V        -1.194  -1.187  -1.173  -1.220  -1.217  -1.183  -1.025  -1.013  -0.987
222   I         0.067   0.021   0.015   0.067  -0.005  -0.024  -0.037  -0.109  -0.119
223   N         0.067   0.021   0.015   0.156   0.090   0.086  -0.037  -0.109  -0.119
224   C         1.803   1.811   1.828   2.037   2.049   2.076   1.940   1.949   1.971
225   C         1.803   1.811   1.828   2.037   2.049   2.076   1.940   1.949   1.971
226   S         0.067   0.021   0.015  -0.097  -0.164  -0.177  -0.037  -0.109  -0.119
227   I         1.803   1.811   1.828   1.837   1.856   1.876   1.940   1.949   1.971
228   V         0.067   0.106   0.043   0.071   0.133   0.026  -0.037   0.025  -0.074
229   R         0.067   0.021   0.015   0.078   0.009  -0.002  -0.037  -0.109  -0.119
230   P         1.803   1.811   1.828   2.029   2.045   2.069   1.940   1.949   1.971
231   V         0.067   0.094   0.036   0.100   0.150   0.051  -0.037   0.007  -0.084
232   L         1.803   1.811   1.828   1.614   1.627   1.653   1.940   1.949   1.971
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   I         0.067   0.021   0.015  -0.012  -0.093  -0.117  -0.037  -0.109  -0.119
238   R         0.067   0.021   0.015  -0.012  -0.095  -0.107  -0.037  -0.109  -0.119
239   R         0.067   0.021   0.015  -0.012  -0.095  -0.107  -0.037  -0.109  -0.119
240   S         0.067   0.021   0.015  -0.070  -0.139  -0.145  -0.037  -0.109  -0.119
241   R         1.803   1.811   1.828   1.788   1.803   1.828   1.940   1.949   1.971
242   Q         0.067   0.106   0.043   0.130   0.192   0.089  -0.037   0.025  -0.074
243   Q         1.803   1.811   1.828   1.885   1.892   1.925   1.940   1.949   1.971
244   R         0.067   0.094   0.036   0.192   0.239   0.136  -0.037   0.007  -0.084
245   R        -1.194  -1.187  -1.173  -1.174  -1.159  -1.136  -1.025  -1.013  -0.987
246   Q        -1.194  -1.187  -1.173  -1.108  -1.110  -1.071  -1.025  -1.013  -0.987
247   M        -1.194  -1.187  -1.173  -1.000  -0.990  -0.963  -1.025  -1.013  -0.987
248   L        -1.194  -1.187  -1.173  -1.133  -1.099  -1.096  -1.025  -1.013  -0.987
249   -        -0.088  -0.084  -0.065  -0.074  -0.068  -0.036  -0.284  -0.277  -0.247
250   -        -0.088  -0.084  -0.065  -0.267  -0.263  -0.229  -0.284  -0.277  -0.247
251   -        -0.088  -0.084  -0.065  -0.170  -0.164  -0.131  -0.284  -0.277  -0.247
252   -        -0.088  -0.084  -0.065  -0.074  -0.068  -0.036  -0.284  -0.277  -0.247
253   -        -0.088  -0.084  -0.065  -0.351  -0.346  -0.313  -0.284  -0.277  -0.247
254   -        -0.088  -0.084  -0.065  -0.050  -0.044  -0.012  -0.284  -0.277  -0.247
255   S         0.067   0.094   0.036   0.022   0.070  -0.040  -0.037   0.007  -0.084
256   R         0.067   0.021   0.015   0.029  -0.046  -0.059  -0.037  -0.109  -0.119
257   R         0.067   0.021   0.015   0.041  -0.031  -0.045  -0.037  -0.109  -0.119
258   E         0.067   0.021   0.015  -0.008  -0.090  -0.111  -0.037  -0.109  -0.119
259   Q        -0.088  -0.084  -0.065  -0.160  -0.153  -0.122  -0.284  -0.277  -0.247
260   H        -0.088  -0.084  -0.065  -0.001   0.006   0.037  -0.284  -0.277  -0.247
261   S        -0.088  -0.084  -0.065  -0.249  -0.243  -0.211  -0.284  -0.277  -0.247
262   Y        -0.088  -0.084  -0.065  -0.111  -0.105  -0.073  -0.284  -0.277  -0.247
263   F        -0.088  -0.084  -0.065  -0.192  -0.186  -0.154  -0.284  -0.277  -0.247
264   L        -0.088  -0.084  -0.065  -0.418  -0.412  -0.380  -0.284  -0.277  -0.247
265   R        -0.088  -0.084  -0.065  -0.160  -0.153  -0.122  -0.284  -0.277  -0.247
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   S        -1.194  -1.187  -1.173  -1.298  -1.280  -1.261  -1.025  -1.013  -0.987
268   S        -1.194  -1.187  -1.173  -1.108  -1.076  -1.071  -1.025  -1.013  -0.987
269   F        -1.194  -1.187  -1.173  -1.005  -0.995  -0.967  -1.025  -1.013  -0.987
270   M         0.067   0.021   0.015   0.126   0.035   0.018  -0.037  -0.109  -0.119
271   N         0.067   0.021   0.015   0.082   0.005  -0.001  -0.037  -0.109  -0.119
272   S        -1.194  -1.187  -1.173  -1.246  -1.226  -1.209  -1.025  -1.013  -0.987
273   N         0.067   0.106   0.043   0.093   0.156   0.057  -0.037   0.025  -0.074
274   S         0.067   0.094   0.036  -0.085  -0.039  -0.144  -0.037   0.007  -0.084
275   S         0.067   0.094   0.036   0.022   0.070  -0.040  -0.037   0.007  -0.084
276   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   S         0.067   0.106   0.043  -0.136  -0.069  -0.175  -0.037   0.025  -0.074
286   A         0.067   0.094   0.036   0.225   0.267   0.172  -0.037   0.007  -0.084
287   D        -1.194  -1.187  -1.173  -1.205  -1.183  -1.167  -1.025  -1.013  -0.987
288   D         1.803   1.811   1.828   1.888   1.900   1.928   1.940   1.949   1.971
289   L         1.803   1.811   1.828   1.582   1.594   1.622   1.940   1.949   1.971
290   H        -0.088  -0.084  -0.065   0.007   0.014   0.045  -0.284  -0.277  -0.247
291   V        -0.088  -0.084  -0.065  -0.324  -0.318  -0.286  -0.284  -0.277  -0.247
292   H         1.803   1.811   1.828   2.030   2.043   2.070   1.940   1.949   1.971
293   T        -0.088  -0.084  -0.065  -0.217  -0.210  -0.178  -0.284  -0.277  -0.247
294   R        -0.088  -0.084  -0.065  -0.200  -0.194  -0.162  -0.284  -0.277  -0.247
295   A        -0.088  -0.084  -0.065  -0.316  -0.310  -0.278  -0.284  -0.277  -0.247
296   Y        -0.088  -0.084  -0.065  -0.072  -0.065  -0.033  -0.284  -0.277  -0.247
297   S        -0.088  -0.084  -0.065  -0.249  -0.243  -0.211  -0.284  -0.277  -0.247
298   L        -0.088  -0.084  -0.065  -0.324  -0.318  -0.286  -0.284  -0.277  -0.247
299   H        -0.088  -0.084  -0.065  -0.001   0.006   0.037  -0.284  -0.277  -0.247
300   S        -0.088  -0.084  -0.065  -0.426  -0.420  -0.388  -0.284  -0.277  -0.247
301   H        -0.088  -0.084  -0.065  -0.064  -0.057  -0.026  -0.284  -0.277  -0.247
302   S         1.803   1.811   1.828   1.571   1.582   1.610   1.940   1.949   1.971
303   D        -0.088  -0.084  -0.065  -0.168  -0.161  -0.130  -0.284  -0.277  -0.247
304   G        -0.088  -0.084  -0.065  -0.080  -0.073  -0.041  -0.284  -0.277  -0.247
305   E        -0.088  -0.084  -0.065  -0.225  -0.218  -0.187  -0.284  -0.277  -0.247
306   G        -0.088  -0.084  -0.065  -0.080  -0.073  -0.041  -0.284  -0.277  -0.247
307   Q        -0.088  -0.084  -0.065  -0.127  -0.121  -0.089  -0.284  -0.277  -0.247
308   D        -0.088  -0.084  -0.065  -0.176  -0.169  -0.138  -0.284  -0.277  -0.247
309   R         1.803   1.811   1.828   1.754   1.766   1.794   1.940   1.949   1.971
310   R        -0.088  -0.084  -0.065  -0.249  -0.243  -0.211  -0.284  -0.277  -0.247
311   S        -0.088  -0.084  -0.065  -0.383  -0.377  -0.345  -0.284  -0.277  -0.247
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   E        -0.088  -0.084  -0.065  -0.136  -0.129  -0.097  -0.284  -0.277  -0.247
314   H        -0.088  -0.084  -0.065  -0.064  -0.057  -0.026  -0.284  -0.277  -0.247
315   E        -0.088  -0.084  -0.065  -0.392  -0.386  -0.354  -0.284  -0.277  -0.247
316   E        -0.088  -0.084  -0.065  -0.152  -0.145  -0.113  -0.284  -0.277  -0.247
317   T        -0.088  -0.084  -0.065  -0.088  -0.081  -0.049  -0.284  -0.277  -0.247
318   H        -1.194  -1.187  -1.173  -0.914  -0.904  -0.876  -1.025  -1.013  -0.987
319   S         1.803   1.811   1.828   1.639   1.654   1.678   1.940   1.949   1.971
320   M        -1.194  -1.187  -1.173  -1.149  -1.128  -1.111  -1.025  -1.013  -0.987
321   G         0.067   0.021   0.015   0.167   0.088   0.078  -0.037  -0.109  -0.119
322   A         0.067   0.021   0.015   0.071  -0.016  -0.025  -0.037  -0.109  -0.119
323   D        -1.194  -1.187  -1.173  -1.205  -1.183  -1.167  -1.025  -1.013  -0.987
324   A        -1.194  -1.187  -1.173  -1.054  -1.058  -1.016  -1.025  -1.013  -0.987
325   D        -1.194  -1.187  -1.173  -1.024  -1.025  -0.987  -1.025  -1.013  -0.987
326   T        -1.194  -1.187  -1.173  -1.277  -1.258  -1.240  -1.025  -1.013  -0.987
327   Y         0.067   0.094   0.036   0.122   0.164   0.080  -0.037   0.007  -0.084
328   R        -1.194  -1.187  -1.173  -1.044  -1.031  -1.007  -1.025  -1.013  -0.987
329   Q        -1.194  -1.187  -1.173  -1.220  -1.204  -1.183  -1.025  -1.013  -0.987
330   T        -1.194  -1.187  -1.173  -1.309  -1.302  -1.272  -1.025  -1.013  -0.987
331   T         1.803   1.811   1.828   1.747   1.754   1.786   1.940   1.949   1.971
332   F         0.067   0.094   0.036   0.181   0.229   0.132  -0.037   0.007  -0.084
333   I        -0.088  -0.084  -0.065  -0.111  -0.105  -0.073  -0.284  -0.277  -0.247
334   P        -0.088  -0.084  -0.065  -0.088  -0.081  -0.049  -0.284  -0.277  -0.247
335   D         1.803   1.811   1.828   1.888   1.900   1.928   1.940   1.949   1.971
336   T        -0.088  -0.084  -0.065  -0.088  -0.081  -0.049  -0.284  -0.277  -0.247
337   P        -0.088  -0.084  -0.065   0.190   0.198   0.228  -0.284  -0.277  -0.247
338   N         1.803   1.811   1.828   1.821   1.833   1.861   1.940   1.949   1.971
339   G         1.803   1.811   1.828   1.921   1.933   1.961   1.940   1.949   1.971
340   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   E        -0.088  -0.084  -0.065  -0.392  -0.386  -0.354  -0.284  -0.277  -0.247
348   C        -0.088  -0.084  -0.065  -0.048  -0.041  -0.010  -0.284  -0.277  -0.247
349   G         1.803   1.811   1.828   1.921   1.933   1.961   1.940   1.949   1.971
350   I        -1.194  -1.187  -1.173  -1.049  -1.032  -1.011  -1.025  -1.013  -0.987
351   E        -1.194  -1.187  -1.173  -0.942  -0.928  -0.905  -1.025  -1.013  -0.987
352   P         0.067   0.021   0.015   0.225   0.140   0.123  -0.037  -0.109  -0.119
353   T        -1.194  -1.187  -1.173  -1.241  -1.217  -1.203  -1.025  -1.013  -0.987
354   Q        -1.194  -1.187  -1.173  -1.246  -1.237  -1.209  -1.025  -1.013  -0.987
355   V        -1.194  -1.187  -1.173  -1.108  -1.098  -1.071  -1.025  -1.013  -0.987
356   S        -1.194  -1.187  -1.173  -1.010  -0.986  -0.972  -1.025  -1.013  -0.987
357   D         0.067   0.094   0.036   0.246   0.291   0.196  -0.037   0.007  -0.084
358   S        -1.194  -1.187  -1.173  -1.298  -1.286  -1.261  -1.025  -1.013  -0.987
359   G         0.067   0.094   0.036   0.093   0.136   0.047  -0.037   0.007  -0.084
360   E        -1.194  -1.187  -1.173  -1.128  -1.114  -1.091  -1.025  -1.013  -0.987
361   W         0.067   0.094   0.036   0.318   0.361   0.284  -0.037   0.007  -0.084
362   S        -1.194  -1.187  -1.173  -1.128  -1.105  -1.091  -1.025  -1.013  -0.987
363   G        -0.088  -0.084  -0.065  -0.308  -0.301  -0.270  -0.284  -0.277  -0.247
364   Q        -0.088  -0.084  -0.065  -0.064  -0.057  -0.026  -0.284  -0.277  -0.247
365   S         0.067   0.021   0.015  -0.070  -0.139  -0.145  -0.037  -0.109  -0.119
366   N         0.067   0.021   0.015   0.056  -0.019  -0.031  -0.037  -0.109  -0.119
367   G        -1.194  -1.187  -1.173  -1.113  -1.108  -1.076  -1.025  -1.013  -0.987
368   Y         1.803   1.811   1.828   1.973   1.983   2.013   1.940   1.949   1.971
369   V         0.067   0.021   0.015   0.010  -0.080  -0.095  -0.037  -0.109  -0.119
370   L         0.067   0.021   0.015  -0.159  -0.236  -0.245  -0.037  -0.109  -0.119
371   V        -1.194  -1.187  -1.173  -0.923  -0.903  -0.886  -1.025  -1.013  -0.987
372   T         0.067   0.021   0.015  -0.085  -0.172  -0.185  -0.037  -0.109  -0.119
373   E         0.067   0.021   0.015   0.115   0.047   0.034  -0.037  -0.109  -0.119
374   L        -1.194  -1.187  -1.173  -1.149  -1.120  -1.111  -1.025  -1.013  -0.987
375   Q         0.067   0.021   0.015   0.130   0.048   0.040  -0.037  -0.109  -0.119
376   E        -1.194  -1.187  -1.173  -1.256  -1.246  -1.219  -1.025  -1.013  -0.987
377   F         1.803   1.811   1.828   1.893   1.905   1.933   1.940   1.949   1.971
378   N         1.803   1.811   1.828   1.804   1.816   1.844   1.940   1.949   1.971
379   K         0.067   0.094   0.036   0.026   0.074  -0.031  -0.037   0.007  -0.084
380   M         0.067   0.106   0.043   0.214   0.280   0.171  -0.037   0.025  -0.074
381   G         0.067   0.106   0.043   0.115   0.182   0.070  -0.037   0.025  -0.074
382   K         1.803   1.811   1.828   1.714   1.719   1.753   1.940   1.949   1.971
383   K         0.067   0.021   0.015  -0.001  -0.081  -0.080  -0.037  -0.109  -0.119
384   L         0.067   0.021   0.015  -0.050  -0.115  -0.118  -0.037  -0.109  -0.119
385   V         0.067   0.106   0.043   0.111   0.176   0.071  -0.037   0.025  -0.074
386   Q         0.067   0.021   0.015   0.119   0.034   0.027  -0.037  -0.109  -0.119
387   E        -1.194  -1.187  -1.173  -1.256  -1.233  -1.219  -1.025  -1.013  -0.987
388   A        -1.194  -1.187  -1.173  -1.159  -1.155  -1.121  -1.025  -1.013  -0.987
389   F         1.803   1.811   1.828   1.893   1.905   1.933   1.940   1.949   1.971
390   R        -1.194  -1.187  -1.173  -1.288  -1.282  -1.250  -1.025  -1.013  -0.987
391   I         0.067   0.094   0.036   0.111   0.157   0.060  -0.037   0.007  -0.084
392   V        -1.194  -1.187  -1.173  -1.128  -1.134  -1.091  -1.025  -1.013  -0.987
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q03080
Output conservation file - output/Q03080
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
