1     M         1.002   1.015   1.071   1.217   1.238   1.302   1.066   1.086   1.172
2     D         1.002   1.015   1.071   0.986   1.005   1.097   1.066   1.086   1.172
3     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     D        -0.880  -0.825  -0.722  -1.073  -0.991  -0.814  -1.119  -1.046  -0.895
8     S        -0.235  -0.185  -0.060  -0.530  -0.445  -0.242  -0.641  -0.561  -0.377
9     S        -0.803  -0.713  -0.704  -0.968  -0.885  -0.848  -1.020  -0.932  -0.874
10    T        -1.166  -1.198  -1.142  -1.221  -1.253  -1.187  -1.210  -1.210  -1.106
11    S        -1.166  -1.152  -1.141  -1.234  -1.190  -1.175  -1.210  -1.165  -1.105
12    K        -0.224  -0.197  -0.060  -0.394  -0.356  -0.140  -0.620  -0.585  -0.377
13    F         0.057  -0.024  -0.030   0.234   0.105   0.060  -0.114  -0.265  -0.320
14    V        -0.670  -0.749  -0.678  -0.830  -0.960  -0.859  -0.873  -0.959  -0.843
15    P         0.380   0.265   0.061   0.564   0.415   0.077   0.392   0.218  -0.154
16    E         0.380   0.265   0.061   0.411   0.269  -0.043   0.392   0.218  -0.154
17    Y        -0.179  -0.199  -0.062  -0.082  -0.126   0.070  -0.534  -0.587  -0.381
18    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
19    R         0.380   0.346   0.066   0.538   0.501   0.090   0.392   0.341  -0.144
20    T        -0.218  -0.414  -0.623   0.003  -0.258  -0.624  -0.198  -0.463  -0.762
21    N        -0.787  -0.952  -1.121  -0.556  -0.776  -1.067  -0.704  -0.901  -1.080
22    F         0.380   0.291   0.065   0.653   0.550   0.218   0.392   0.257  -0.147
23    K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
24    N        -1.323  -1.529  -1.529  -1.093  -1.411  -1.476  -1.126  -1.335  -1.288
25    K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
26    G        -0.218  -0.288  -0.611  -0.009  -0.104  -0.608  -0.198  -0.294  -0.745
27    R        -1.323  -1.529  -1.529  -1.018  -1.332  -1.395  -1.126  -1.335  -1.288
28    F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
29    S        -0.891  -0.895  -0.722  -1.090  -1.094  -0.824  -1.126  -1.127  -0.896
30    A        -0.512  -0.451  -0.635  -0.592  -0.483  -0.747  -0.620  -0.523  -0.779
31    D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
32    E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
33    L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
34    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
35    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
36    R         0.380   0.265   0.061   0.530   0.386   0.058   0.392   0.218  -0.154
37    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
38    D        -0.224  -0.153  -0.049  -0.533  -0.408  -0.243  -0.620  -0.500  -0.356
39    T        -0.670  -0.598  -0.676  -0.739  -0.691  -0.750  -0.873  -0.822  -0.841
40    Q        -0.512  -0.452  -0.637  -0.419  -0.332  -0.617  -0.620  -0.524  -0.782
41    Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
42    V         0.057  -0.052  -0.032   0.002  -0.193  -0.197  -0.114  -0.315  -0.324
43    E         0.057   0.166   0.024  -0.034   0.130  -0.108  -0.114   0.060  -0.220
44    L        -0.224  -0.189  -0.055  -0.654  -0.584  -0.348  -0.620  -0.569  -0.368
45    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
46    K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
47    A        -0.720  -0.604  -0.672  -0.957  -0.802  -0.828  -0.957  -0.832  -0.837
48    K         0.380   0.346   0.066   0.535   0.499   0.089   0.392   0.341  -0.144
49    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
50    D        -0.134   0.014   0.002  -0.361  -0.107  -0.148  -0.451  -0.196  -0.261
51    E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
52    A        -1.716  -1.718  -1.544  -1.782  -1.765  -1.528  -1.547  -1.526  -1.301
53    L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
54    A        -0.774  -0.816  -0.712  -0.986  -1.062  -0.903  -0.957  -1.024  -0.883
55    K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
56    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
57    R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
58    N         0.380   0.348   0.067   0.484   0.455   0.045   0.392   0.343  -0.142
59    F        -1.545  -1.577  -1.534  -1.282  -1.412  -1.303  -1.379  -1.414  -1.293
60    I        -1.991  -1.898  -1.819  -1.902  -1.778  -1.693  -1.632  -1.548  -1.391
61    P        -1.991  -1.892  -1.820  -1.930  -1.804  -1.704  -1.632  -1.529  -1.390
62    P        -1.991  -1.930  -1.842  -1.827  -1.786  -1.689  -1.632  -1.573  -1.407
63    T        -1.371  -1.365  -1.181  -1.536  -1.562  -1.293  -1.400  -1.379  -1.144
64    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    G        -0.914  -1.026  -1.136  -0.707  -0.905  -1.106  -0.854  -1.002  -1.097
66    A        -1.472  -1.393  -1.510  -1.311  -1.210  -1.442  -1.281  -1.208  -1.271
67    D        -0.787  -0.840  -1.105  -0.583  -0.661  -1.073  -0.704  -0.773  -1.063
68    S        -0.914  -1.147  -1.160  -0.783  -1.147  -1.188  -0.854  -1.131  -1.122
69    D        -1.277  -1.371  -1.187  -1.317  -1.438  -1.165  -1.303  -1.383  -1.150
70    E        -0.923  -0.857  -0.718  -1.227  -1.149  -0.923  -1.163  -1.083  -0.890
71    E         0.270   0.155   0.017   0.264   0.102  -0.134   0.230   0.042  -0.233
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -0.803  -0.764  -0.697  -0.993  -0.940  -0.822  -1.020  -0.976  -0.866
74    -        -2.195  -2.115  -1.858  -2.024  -1.932  -1.570  -1.779  -1.699  -1.417
75    D        -1.716  -1.712  -1.542  -1.783  -1.792  -1.556  -1.547  -1.521  -1.299
76    E        -1.337  -1.231  -1.167  -1.437  -1.285  -1.188  -1.379  -1.270  -1.132
77    S        -1.716  -1.608  -1.522  -1.808  -1.664  -1.538  -1.547  -1.437  -1.283
78    S        -1.166  -1.131  -1.138  -1.314  -1.292  -1.248  -1.210  -1.176  -1.104
79    V        -1.991  -1.871  -1.821  -1.894  -1.728  -1.678  -1.632  -1.519  -1.391
80    S        -1.612  -1.543  -1.511  -1.633  -1.538  -1.481  -1.463  -1.391  -1.275
81    A        -1.991  -1.991  -1.839  -1.980  -1.987  -1.753  -1.632  -1.614  -1.404
82    D        -1.612  -1.662  -1.531  -1.626  -1.685  -1.492  -1.463  -1.479  -1.290
83    Q        -1.716  -1.698  -1.533  -1.700  -1.652  -1.424  -1.547  -1.504  -1.292
84    Q        -1.323  -1.362  -1.502  -1.072  -1.139  -1.371  -1.126  -1.171  -1.263
85    F        -1.048  -1.199  -1.162  -0.826  -1.076  -1.044  -1.041  -1.211  -1.127
86    Y        -0.066  -0.177  -0.059  -0.016  -0.272  -0.117  -0.327  -0.545  -0.376
87    S        -1.764  -1.676  -1.544  -1.754  -1.653  -1.432  -1.582  -1.499  -1.301
88    Q        -0.512  -0.501  -0.638  -0.475  -0.442  -0.682  -0.620  -0.586  -0.783
89    L        -0.218  -0.364  -0.617  -0.152  -0.317  -0.597  -0.198  -0.397  -0.754
90    Q        -1.048  -1.160  -1.147  -0.970  -1.143  -1.145  -1.041  -1.164  -1.111
91    Q        -1.048  -1.190  -1.163  -1.021  -1.267  -1.259  -1.041  -1.204  -1.127
92    E        -1.048  -1.128  -1.142  -1.052  -1.168  -1.219  -1.041  -1.121  -1.106
93    L         0.057  -0.025  -0.031  -0.091  -0.211  -0.201  -0.114  -0.266  -0.322
94    P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
95    Q        -1.545  -1.457  -1.506  -1.426  -1.285  -1.428  -1.379  -1.275  -1.268
96    M         0.057  -0.052  -0.032   0.196  -0.019  -0.077  -0.114  -0.315  -0.324
97    T        -1.716  -1.648  -1.527  -1.762  -1.680  -1.441  -1.547  -1.476  -1.288
98    Q        -1.270  -1.273  -1.160  -1.401  -1.415  -1.235  -1.294  -1.287  -1.124
99    Q        -1.991  -2.062  -1.851  -1.759  -1.884  -1.605  -1.632  -1.662  -1.412
100   L        -0.774  -0.810  -0.715  -0.983  -1.065  -0.942  -0.957  -1.014  -0.886
101   N        -1.991  -1.976  -1.836  -1.633  -1.582  -1.354  -1.632  -1.599  -1.402
102   S         0.057   0.166   0.024  -0.048   0.120  -0.139  -0.114   0.060  -0.220
103   D        -1.337  -1.239  -1.162  -1.444  -1.309  -1.154  -1.379  -1.274  -1.128
104   D        -0.218  -0.288  -0.611  -0.073  -0.162  -0.662  -0.198  -0.294  -0.745
105   M        -1.441  -1.282  -1.174  -1.502  -1.299  -1.136  -1.463  -1.285  -1.138
106   Q        -0.958  -0.872  -0.713  -1.238  -1.104  -0.857  -1.210  -1.098  -0.884
107   E        -2.369  -2.249  -2.097  -2.383  -2.236  -1.995  -1.800  -1.697  -1.483
108   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
109   L         0.057  -0.010  -0.023  -0.156  -0.271  -0.305  -0.114  -0.240  -0.308
110   S        -1.716  -1.650  -1.538  -1.791  -1.701  -1.506  -1.547  -1.487  -1.297
111   A         0.380   0.503   0.079   0.350   0.499  -0.062   0.392   0.562  -0.121
112   T         0.380   0.265   0.061   0.532   0.393   0.059   0.392   0.218  -0.154
113   V        -0.670  -0.746  -0.688  -0.756  -0.866  -0.782  -0.873  -0.965  -0.855
114   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
115   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
116   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
117   Q        -0.224  -0.189  -0.055  -0.446  -0.381  -0.170  -0.620  -0.569  -0.368
118   I        -1.545  -1.602  -1.536  -1.548  -1.664  -1.536  -1.379  -1.434  -1.295
119   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
120   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
121   R        -0.224  -0.189  -0.055  -0.393  -0.341  -0.131  -0.620  -0.569  -0.368
122   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
123   H        -0.774  -0.858  -0.721  -0.590  -0.770  -0.612  -0.957  -1.078  -0.894
124   R        -1.048  -1.049  -1.123  -0.896  -0.858  -0.984  -1.041  -1.017  -1.084
125   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
126   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
127   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
128   D        -1.048  -1.120  -1.141  -0.989  -1.089  -1.153  -1.041  -1.111  -1.104
129   V        -1.991  -1.951  -1.840  -2.040  -1.987  -1.790  -1.632  -1.593  -1.405
130   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
131   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
132   Q        -1.819  -1.834  -1.819  -1.584  -1.650  -1.652  -1.463  -1.478  -1.389
133   A        -1.441  -1.346  -1.187  -1.452  -1.295  -1.114  -1.463  -1.355  -1.150
134   G         0.380   0.346   0.066   0.518   0.475   0.056   0.392   0.341  -0.144
135   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
136   V         0.057   0.166   0.024   0.002   0.169  -0.086  -0.114   0.060  -0.220
137   P        -0.787  -0.952  -1.121  -0.457  -0.692  -0.983  -0.704  -0.901  -1.080
138   R        -0.720  -0.692  -0.670  -0.739  -0.671  -0.599  -0.957  -0.899  -0.832
139   L        -0.224  -0.189  -0.055  -0.507  -0.401  -0.189  -0.620  -0.569  -0.368
140   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
141   E        -0.512  -0.433  -0.648  -0.535  -0.443  -0.746  -0.620  -0.536  -0.801
142   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
143   M        -0.224  -0.189  -0.055  -0.404  -0.409  -0.191  -0.620  -0.569  -0.368
144   R        -1.716  -1.682  -1.529  -1.663  -1.637  -1.411  -1.547  -1.505  -1.290
145   E        -1.166  -1.144  -1.153  -1.211  -1.172  -1.110  -1.210  -1.184  -1.118
146   N        -1.716  -1.621  -1.544  -1.692  -1.584  -1.452  -1.547  -1.464  -1.301
147   Q        -0.670  -0.627  -0.651  -0.539  -0.422  -0.518  -0.873  -0.775  -0.802
148   P         1.002   1.015   1.071   1.103   1.121   1.201   1.066   1.086   1.172
149   E        -1.716  -1.732  -1.545  -1.669  -1.645  -1.362  -1.547  -1.538  -1.302
150   M        -0.224  -0.189  -0.055  -0.404  -0.409  -0.191  -0.620  -0.569  -0.368
151   L         0.380   0.348   0.067   0.302   0.269  -0.121   0.392   0.343  -0.142
152   Q         0.380   0.291   0.065   0.471   0.368   0.033   0.392   0.257  -0.147
153   L        -0.224  -0.189  -0.055  -0.507  -0.401  -0.189  -0.620  -0.569  -0.368
154   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
155   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
156   A         0.380   0.291   0.065   0.345   0.239  -0.098   0.392   0.257  -0.147
157   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
158   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
159   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
160   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
161   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
162   I         0.380   0.291   0.065   0.409   0.299  -0.036   0.392   0.257  -0.147
163   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
164   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
165   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
166   T        -1.048  -0.970  -1.138  -0.925  -0.860  -1.099  -1.041  -0.982  -1.101
167   S        -0.218  -0.363  -0.616  -0.102  -0.293  -0.696  -0.198  -0.396  -0.753
168   A        -2.094  -2.043  -1.837  -2.130  -2.031  -1.734  -1.716  -1.653  -1.403
169   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
170   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
171   K        -1.270  -1.266  -1.165  -1.180  -1.153  -1.016  -1.294  -1.273  -1.129
172   V         0.380   0.265   0.061   0.456   0.311  -0.018   0.392   0.218  -0.154
173   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
174   V         0.380   0.348   0.067   0.456   0.420  -0.006   0.392   0.343  -0.142
175   D        -0.224  -0.194  -0.062  -0.526  -0.482  -0.265  -0.620  -0.578  -0.381
176   A        -0.134  -0.142  -0.057  -0.432  -0.456  -0.319  -0.451  -0.479  -0.371
177   D        -0.512  -0.410  -0.646  -0.431  -0.322  -0.665  -0.620  -0.514  -0.798
178   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
179   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
180   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
181   L        -0.787  -0.996  -1.129  -0.739  -1.026  -1.223  -0.704  -0.953  -1.089
182   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
183   I        -0.224  -0.172  -0.054  -0.523  -0.430  -0.244  -0.620  -0.535  -0.366
184   Q        -0.787  -0.931  -1.120  -0.549  -0.744  -1.029  -0.704  -0.876  -1.079
185   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
186   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
187   Y        -1.048  -1.167  -1.163  -0.791  -1.026  -1.049  -1.041  -1.186  -1.127
188   T         0.057   0.210   0.040   0.004   0.223  -0.035  -0.114   0.130  -0.191
189   G        -1.716  -1.567  -1.528  -1.616  -1.390  -1.363  -1.547  -1.391  -1.287
190   S        -0.224  -0.189  -0.055  -0.549  -0.498  -0.271  -0.620  -0.569  -0.368
191   V        -1.991  -2.062  -1.851  -1.895  -1.976  -1.669  -1.632  -1.662  -1.412
192   E        -0.670  -0.712  -0.688  -0.819  -0.889  -0.813  -0.873  -0.932  -0.855
193   V         0.380   0.484   0.079   0.443   0.574  -0.022   0.392   0.537  -0.121
194   K        -0.720  -0.583  -0.673  -0.779  -0.582  -0.678  -0.957  -0.785  -0.836
195   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
196   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
197   A         0.380   0.265   0.061   0.350   0.212  -0.092   0.392   0.218  -0.154
198   I        -0.224  -0.189  -0.055  -0.531  -0.470  -0.247  -0.620  -0.569  -0.368
199   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
200   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
201   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
202   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
203   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
204   V        -0.224  -0.189  -0.055  -0.523  -0.479  -0.253  -0.620  -0.569  -0.368
205   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
206   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
207   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
208   S         0.380   0.477   0.079   0.409   0.527  -0.052   0.392   0.527  -0.122
209   T        -1.337  -1.231  -1.169  -1.368  -1.219  -1.148  -1.379  -1.266  -1.134
210   D        -1.545  -1.613  -1.534  -1.433  -1.548  -1.426  -1.379  -1.442  -1.293
211   Y        -0.720  -0.599  -0.673  -0.566  -0.390  -0.496  -0.957  -0.797  -0.835
212   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
213   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
214   Y        -0.218  -0.221  -0.597   0.200   0.192  -0.317  -0.198  -0.213  -0.726
215   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
216   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
217   Q        -1.545  -1.562  -1.521  -1.460  -1.491  -1.451  -1.379  -1.389  -1.283
218   C         0.380   0.265   0.061   0.690   0.541   0.193   0.392   0.218  -0.154
219   N        -1.270  -1.089  -1.150  -1.277  -1.011  -1.124  -1.294  -1.092  -1.114
220   A         0.057  -0.052  -0.032  -0.093  -0.275  -0.256  -0.114  -0.315  -0.324
221   M        -0.224  -0.189  -0.055  -0.404  -0.409  -0.191  -0.620  -0.569  -0.368
222   E        -1.166  -1.113  -1.138  -1.254  -1.181  -1.185  -1.210  -1.155  -1.105
223   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
224   I        -0.891  -0.723  -0.684  -1.250  -0.977  -0.912  -1.126  -0.896  -0.846
225   L         0.380   0.346   0.066   0.295   0.259  -0.143   0.392   0.341  -0.144
226   G        -1.991  -1.750  -1.821  -1.788  -1.453  -1.538  -1.632  -1.412  -1.392
227   L        -0.134  -0.180  -0.060  -0.485  -0.582  -0.369  -0.451  -0.551  -0.377
228   F        -1.048  -1.190  -1.163  -0.911  -1.193  -1.221  -1.041  -1.204  -1.127
229   N        -1.545  -1.645  -1.531  -1.429  -1.577  -1.424  -1.379  -1.459  -1.291
230   S        -1.323  -1.237  -1.484  -1.106  -1.003  -1.368  -1.126  -1.038  -1.247
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   N        -2.094  -2.026  -1.847  -1.954  -1.850  -1.624  -1.716  -1.640  -1.410
234   K        -0.218  -0.414  -0.623   0.011  -0.248  -0.592  -0.198  -0.463  -0.762
235   P        -1.716  -1.510  -1.527  -1.679  -1.454  -1.380  -1.547  -1.362  -1.288
236   S         0.380   0.484   0.079   0.437   0.559   0.030   0.392   0.537  -0.121
237   L        -0.224  -0.189  -0.055  -0.466  -0.350  -0.145  -0.620  -0.569  -0.368
238   I        -0.134  -0.180  -0.060  -0.435  -0.559  -0.361  -0.451  -0.550  -0.377
239   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
240   T        -0.224  -0.189  -0.055  -0.423  -0.370  -0.165  -0.620  -0.569  -0.368
241   A         0.380   0.291   0.065   0.345   0.239  -0.098   0.392   0.257  -0.147
242   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
243   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
244   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
245   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
246   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
247   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
248   L        -0.512  -0.622  -0.669  -0.550  -0.681  -0.690  -0.620  -0.767  -0.828
249   C         1.002   1.015   1.071   1.217   1.231   1.302   1.066   1.086   1.172
250   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
251   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
252   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
253   K        -1.612  -1.557  -1.517  -1.466  -1.370  -1.302  -1.463  -1.390  -1.278
254   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
255   Q         0.380   0.265   0.061   0.477   0.342   0.042   0.392   0.218  -0.154
256   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
257   D         0.380   0.265   0.061   0.459   0.318   0.002   0.392   0.218  -0.154
258   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
259   S        -0.670  -0.695  -0.676  -0.805  -0.843  -0.797  -0.873  -0.903  -0.841
260   V        -1.337  -1.354  -1.173  -1.460  -1.465  -1.195  -1.379  -1.374  -1.138
261   V        -0.224  -0.189  -0.055  -0.523  -0.479  -0.253  -0.620  -0.569  -0.368
262   S        -0.787  -0.776  -1.098  -0.622  -0.618  -1.106  -0.704  -0.696  -1.056
263   Q        -1.323  -1.394  -1.500  -1.002  -1.108  -1.240  -1.126  -1.204  -1.262
264   A         0.380   0.291   0.065   0.350   0.246  -0.086   0.392   0.257  -0.147
265   L        -0.670  -0.730  -0.678  -0.946  -1.017  -0.906  -0.873  -0.929  -0.842
266   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
267   T        -1.048  -1.199  -1.164  -0.945  -1.200  -1.197  -1.041  -1.212  -1.128
268   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
269   A        -0.512  -0.442  -0.648  -0.600  -0.513  -0.795  -0.620  -0.539  -0.802
270   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
271   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
272   I        -0.218  -0.363  -0.616  -0.138  -0.342  -0.756  -0.198  -0.396  -0.753
273   Y         0.380   0.346   0.066   0.686   0.649   0.238   0.392   0.341  -0.144
274   S         0.380   0.291   0.065   0.437   0.330   0.006   0.392   0.257  -0.147
275   M        -2.094  -2.026  -1.847  -1.899  -1.859  -1.544  -1.716  -1.640  -1.410
276   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
277   T        -1.991  -1.979  -1.839  -1.860  -1.878  -1.701  -1.632  -1.611  -1.405
278   E         0.380   0.291   0.065   0.411   0.304  -0.036   0.392   0.257  -0.147
279   T        -0.670  -0.761  -0.690  -0.721  -0.868  -0.765  -0.873  -0.979  -0.857
280   L         0.380   0.265   0.061   0.295   0.152  -0.153   0.392   0.218  -0.154
281   V        -0.134  -0.113  -0.052  -0.336  -0.311  -0.240  -0.451  -0.427  -0.362
282   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
283   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
284   C         0.380   0.291   0.065   0.669   0.547   0.141   0.392   0.257  -0.147
285   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
286   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
287   I         0.057   0.166   0.024  -0.035   0.126  -0.107  -0.114   0.060  -0.220
288   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
289   Y         1.002   1.015   1.071   1.195   1.212   1.283   1.066   1.086   1.172
290   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
291   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
292   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
293   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
294   P        -1.166  -1.213  -1.153  -1.103  -1.168  -1.110  -1.210  -1.235  -1.118
295   Q        -1.991  -1.711  -1.821  -1.863  -1.463  -1.660  -1.632  -1.389  -1.392
296   E        -0.512  -0.503  -0.654  -0.534  -0.509  -0.755  -0.620  -0.599  -0.808
297   A        -0.720  -0.572  -0.673  -0.916  -0.676  -0.785  -0.957  -0.777  -0.835
298   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
299   Q         0.380   0.265   0.061   0.470   0.332   0.023   0.392   0.218  -0.154
300   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
301   V         0.057  -0.052  -0.032   0.002  -0.193  -0.197  -0.114  -0.315  -0.324
302   I        -0.670  -0.705  -0.669  -0.849  -0.888  -0.846  -0.873  -0.889  -0.831
303   D         0.380   0.348   0.067   0.451   0.414  -0.010   0.392   0.343  -0.142
304   V         0.057   0.059  -0.026  -0.093  -0.090  -0.245  -0.114  -0.120  -0.313
305   R        -0.224  -0.189  -0.055  -0.398  -0.352  -0.137  -0.620  -0.569  -0.368
306   I         0.380   0.265   0.061   0.439   0.305   0.043   0.392   0.218  -0.154
307   P         0.380   0.265   0.061   0.554   0.403   0.048   0.392   0.218  -0.154
308   K        -1.337  -1.295  -1.168  -1.219  -1.147  -0.958  -1.379  -1.306  -1.132
309   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
310   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
311   V         0.380   0.346   0.066   0.456   0.419  -0.008   0.392   0.341  -0.144
312   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
313   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
314   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
315   S        -0.891  -0.883  -0.720  -0.992  -0.969  -0.712  -1.126  -1.112  -0.892
316   H         0.380   0.265   0.061   0.722   0.567   0.207   0.392   0.218  -0.154
317   E        -1.337  -1.330  -1.177  -1.459  -1.427  -1.208  -1.379  -1.356  -1.141
318   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
319   T        -0.218  -0.414  -0.623  -0.008  -0.272  -0.653  -0.198  -0.463  -0.762
320   L        -1.048  -1.219  -1.164  -1.145  -1.393  -1.288  -1.041  -1.226  -1.128
321   V         0.380   0.265   0.061   0.456   0.311  -0.018   0.392   0.218  -0.154
322   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
323   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
324   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
325   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
326   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
327   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
328   A        -0.224  -0.189  -0.055  -0.602  -0.535  -0.306  -0.620  -0.569  -0.368
329   V         0.057   0.166   0.024   0.002   0.169  -0.086  -0.114   0.060  -0.220
330   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
331   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
332   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
333   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
334   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
335   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
336   N        -1.166  -1.171  -1.156  -1.187  -1.190  -1.145  -1.210  -1.207  -1.121
337   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
338   L        -1.166  -1.109  -1.132  -1.282  -1.161  -1.159  -1.210  -1.120  -1.094
339   Q         0.380   0.484   0.079   0.497   0.617   0.128   0.392   0.537  -0.121
340   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
341   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
342   V        -0.224  -0.188  -0.060  -0.531  -0.477  -0.261  -0.620  -0.567  -0.377
343   V        -0.134  -0.180  -0.060  -0.336  -0.448  -0.258  -0.451  -0.550  -0.377
344   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
345   N         0.380   0.265   0.061   0.476   0.340   0.011   0.392   0.218  -0.154
346   A        -0.224  -0.163  -0.055  -0.375  -0.252  -0.120  -0.620  -0.520  -0.368
347   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
348   V        -0.224  -0.131  -0.035  -0.580  -0.416  -0.262  -0.620  -0.460  -0.331
349   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
350   P        -1.048  -1.045  -1.132  -0.910  -0.927  -1.105  -1.041  -1.047  -1.096
351   A         0.380   0.348   0.067   0.379   0.352   0.004   0.392   0.343  -0.142
352   L         0.380   0.265   0.061   0.324   0.194  -0.068   0.392   0.218  -0.154
353   R        -1.337  -1.295  -1.168  -1.538  -1.464  -1.257  -1.379  -1.306  -1.132
354   L        -1.716  -1.529  -1.529  -1.726  -1.447  -1.475  -1.547  -1.356  -1.288
355   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
356   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
357   S        -1.048  -0.904  -1.118  -1.015  -0.801  -1.131  -1.041  -0.867  -1.077
358   S        -0.218  -0.364  -0.617  -0.073  -0.254  -0.622  -0.198  -0.397  -0.754
359   P        -0.787  -0.861  -1.106  -0.462  -0.577  -0.969  -0.704  -0.800  -1.064
360   K         0.380   0.291   0.065   0.535   0.429   0.086   0.392   0.257  -0.147
361   E        -0.224  -0.199  -0.061  -0.533  -0.495  -0.264  -0.620  -0.588  -0.380
362   N        -1.441  -1.387  -1.187  -1.537  -1.462  -1.165  -1.463  -1.401  -1.150
363   I         0.380   0.291   0.065   0.409   0.299  -0.036   0.392   0.257  -0.147
364   K         0.380   0.517   0.081   0.538   0.695   0.116   0.392   0.580  -0.117
365   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
366   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
367   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
368   C         1.002   1.015   1.071   1.217   1.231   1.302   1.066   1.086   1.172
369   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
370   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
371   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
372   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
373   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
374   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
375   T         1.002   1.015   1.071   1.061   1.085   1.164   1.066   1.086   1.172
376   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
377   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
378   N         0.380   0.457   0.077   0.486   0.586   0.066   0.392   0.499  -0.125
379   T        -0.134  -0.164  -0.057  -0.263  -0.340  -0.191  -0.451  -0.520  -0.372
380   E        -1.991  -2.062  -1.851  -1.942  -2.054  -1.756  -1.632  -1.662  -1.412
381   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
382   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
383   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
384   A        -0.670  -0.721  -0.675  -0.854  -0.904  -0.783  -0.873  -0.924  -0.840
385   V         0.380   0.265   0.061   0.456   0.311  -0.018   0.392   0.218  -0.154
386   I         0.380   0.484   0.079   0.409   0.532  -0.011   0.392   0.537  -0.121
387   D         0.057  -0.052  -0.032  -0.002  -0.198  -0.200  -0.114  -0.315  -0.324
388   A         0.057  -0.025  -0.031  -0.103  -0.242  -0.271  -0.114  -0.266  -0.322
389   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
390   L         0.057  -0.010  -0.023  -0.156  -0.271  -0.305  -0.114  -0.240  -0.308
391   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
392   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
393   P         0.057   0.166   0.024   0.121   0.282   0.022  -0.114   0.060  -0.220
394   L        -0.218  -0.064  -0.594  -0.231  -0.039  -0.763  -0.198  -0.000  -0.721
395   V         0.057   0.059  -0.026  -0.035  -0.038  -0.199  -0.114  -0.120  -0.313
396   K        -1.337  -1.235  -1.164  -1.198  -1.011  -0.957  -1.379  -1.250  -1.128
397   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
398   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
399   E        -1.337  -1.280  -1.166  -1.515  -1.395  -1.220  -1.379  -1.292  -1.129
400   V        -1.545  -1.450  -1.507  -1.219  -1.096  -1.172  -1.379  -1.292  -1.270
401   A        -0.134  -0.079  -0.042  -0.389  -0.299  -0.243  -0.451  -0.363  -0.344
402   E        -0.224  -0.153  -0.049  -0.526  -0.394  -0.236  -0.620  -0.500  -0.356
403   Y        -0.787  -0.931  -1.120  -0.377  -0.581  -0.950  -0.704  -0.876  -1.079
404   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
405   T         0.057   0.060  -0.026   0.071   0.073  -0.131  -0.114  -0.117  -0.313
406   K        -0.218  -0.339  -0.615   0.012  -0.145  -0.577  -0.198  -0.363  -0.752
407   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
408   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
409   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
410   C         1.002   1.015   1.071   1.217   1.231   1.302   1.066   1.086   1.172
411   W         1.002   1.015   1.071   1.237   1.252   1.320   1.066   1.086   1.172
412   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
413   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
414   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
415   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
416   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
417   S        -0.224  -0.189  -0.055  -0.471  -0.399  -0.186  -0.620  -0.569  -0.368
418   S         1.002   1.015   1.071   0.958   0.975   1.072   1.066   1.086   1.172
419   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
420   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
421   L         0.380   0.291   0.065   0.287   0.177  -0.168   0.392   0.257  -0.147
422   Q        -1.991  -1.992  -1.837  -1.737  -1.759  -1.508  -1.632  -1.614  -1.402
423   R        -0.720  -0.762  -0.673  -0.779  -0.819  -0.680  -0.957  -0.982  -0.838
424   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
425   D         0.057   0.200   0.028  -0.002   0.214  -0.083  -0.114   0.116  -0.213
426   I        -0.134   0.014   0.002  -0.335  -0.072  -0.128  -0.451  -0.196  -0.261
427   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
428   R         1.002   1.015   1.071   1.059   1.078   1.162   1.066   1.086   1.172
429   Y         1.002   1.015   1.071   1.195   1.212   1.283   1.066   1.086   1.172
430   L         0.380   0.484   0.079   0.332   0.453  -0.017   0.392   0.537  -0.121
431   V         1.002   1.015   1.071   0.991   1.013   1.102   1.066   1.086   1.172
432   S        -0.787  -0.931  -1.120  -0.642  -0.852  -1.188  -0.704  -0.876  -1.079
433   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
434   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
435   C        -0.218  -0.414  -0.623   0.147  -0.128  -0.532  -0.198  -0.463  -0.762
436   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
437   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
438   P         1.002   1.015   1.071   1.097   1.114   1.195   1.066   1.086   1.172
439   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
440   C         1.002   1.015   1.071   1.217   1.231   1.302   1.066   1.086   1.172
441   D         0.380   0.291   0.065   0.459   0.352   0.009   0.392   0.257  -0.147
442   L         0.380   0.265   0.061   0.332   0.206  -0.044   0.392   0.218  -0.154
443   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
444   E        -1.612  -1.602  -1.521  -1.693  -1.664  -1.519  -1.463  -1.431  -1.282
445   I        -1.716  -1.733  -1.548  -1.638  -1.625  -1.373  -1.547  -1.538  -1.304
446   A        -1.323  -1.529  -1.529  -1.139  -1.426  -1.394  -1.126  -1.335  -1.288
447   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
448   N        -0.218  -0.064  -0.594  -0.043   0.152  -0.591  -0.198  -0.000  -0.721
449   R        -0.134   0.014   0.002  -0.222   0.027  -0.024  -0.451  -0.196  -0.261
450   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
451   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
452   E        -0.224  -0.189  -0.055  -0.529  -0.464  -0.245  -0.620  -0.569  -0.368
453   V         0.380   0.346   0.066   0.456   0.419  -0.008   0.392   0.341  -0.144
454   T        -0.670  -0.712  -0.688  -0.777  -0.881  -0.826  -0.873  -0.932  -0.855
455   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
456   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
457   A        -0.774  -0.741  -0.691  -0.970  -0.926  -0.847  -0.957  -0.922  -0.855
458   L        -0.134  -0.151  -0.058  -0.485  -0.529  -0.366  -0.451  -0.497  -0.373
459   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
460   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
461   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
462   L         1.002   1.015   1.071   0.831   0.854   0.960   1.066   1.086   1.172
463   K         0.057  -0.011  -0.029   0.099  -0.015  -0.081  -0.114  -0.241  -0.319
464   M        -0.224  -0.189  -0.055  -0.307  -0.286  -0.083  -0.620  -0.569  -0.368
465   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
466   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
467   A        -1.545  -1.442  -1.514  -1.328  -1.246  -1.383  -1.379  -1.297  -1.276
468   D         1.002   1.015   1.071   0.986   1.006   1.097   1.066   1.086   1.172
469   K        -0.224  -0.199  -0.061  -0.394  -0.359  -0.142  -0.620  -0.587  -0.379
470   E        -1.323  -1.529  -1.529  -1.091  -1.384  -1.381  -1.126  -1.335  -1.288
471   A        -1.545  -1.496  -1.517  -1.448  -1.378  -1.389  -1.379  -1.348  -1.279
472   R        -0.787  -0.996  -1.129  -0.530  -0.832  -1.105  -0.704  -0.953  -1.089
473   G        -1.323  -1.359  -1.502  -1.047  -1.137  -1.392  -1.126  -1.172  -1.264
474   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
475   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
476   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
477   L        -1.716  -1.582  -1.530  -1.901  -1.657  -1.618  -1.547  -1.405  -1.289
478   N        -1.716  -1.705  -1.534  -1.768  -1.724  -1.472  -1.547  -1.513  -1.293
479   I        -0.670  -0.606  -0.661  -0.821  -0.696  -0.773  -0.873  -0.759  -0.817
480   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
481   E        -0.787  -0.996  -1.129  -0.647  -0.948  -1.186  -0.704  -0.953  -1.089
482   N        -0.224  -0.119  -0.032  -0.315  -0.105  -0.010  -0.620  -0.438  -0.325
483   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
484   D        -0.891  -0.861  -0.708  -1.221  -1.173  -0.921  -1.126  -1.082  -0.877
485   F        -0.670  -0.604  -0.668  -0.550  -0.482  -0.580  -0.873  -0.821  -0.831
486   I         0.057  -0.052  -0.032  -0.035  -0.224  -0.210  -0.114  -0.315  -0.324
487   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
488   K        -0.891  -0.840  -0.704  -1.093  -1.019  -0.813  -1.126  -1.053  -0.872
489   A         0.380   0.348   0.067   0.379   0.352   0.004   0.392   0.343  -0.142
490   G         0.380   0.346   0.066   0.518   0.475   0.056   0.392   0.341  -0.144
491   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
492   M         1.002   1.015   1.071   1.217   1.238   1.302   1.066   1.086   1.172
493   E         0.057  -0.052  -0.032  -0.034  -0.221  -0.211  -0.114  -0.315  -0.324
494   K        -0.787  -0.996  -1.124  -0.523  -0.817  -1.075  -0.704  -0.954  -1.084
495   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
496   F        -0.224  -0.189  -0.055  -0.190  -0.129   0.062  -0.620  -0.569  -0.368
497   N        -1.337  -1.324  -1.174  -1.501  -1.481  -1.260  -1.379  -1.348  -1.138
498   C         0.057   0.052  -0.025   0.196   0.172  -0.060  -0.114  -0.131  -0.312
499   Q         1.002   1.015   1.071   0.992   1.015   1.103   1.066   1.086   1.172
500   Q        -1.716  -1.662  -1.535  -1.742  -1.668  -1.484  -1.547  -1.491  -1.295
501   N         0.057  -0.052  -0.032   0.022  -0.167  -0.176  -0.114  -0.315  -0.324
502   E        -1.991  -2.028  -1.838  -1.946  -2.014  -1.716  -1.632  -1.641  -1.404
503   N         1.002   1.015   1.071   1.006   1.033   1.115   1.066   1.086   1.172
504   D        -1.048  -1.099  -1.128  -1.034  -1.086  -1.160  -1.041  -1.075  -1.088
505   K        -1.545  -1.593  -1.534  -1.423  -1.550  -1.464  -1.379  -1.427  -1.293
506   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
507   Y         1.002   1.015   1.071   1.195   1.212   1.283   1.066   1.086   1.172
508   E        -1.545  -1.653  -1.532  -1.462  -1.627  -1.428  -1.379  -1.468  -1.291
509   K         1.002   1.015   1.071   1.056   1.076   1.159   1.066   1.086   1.172
510   A         1.002   1.015   1.071   0.879   0.903   1.002   1.066   1.086   1.172
511   Y         0.057   0.182   0.007   0.261   0.437   0.137  -0.114   0.086  -0.251
512   K        -1.716  -1.678  -1.541  -1.650  -1.618  -1.402  -1.547  -1.504  -1.299
513   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
514   I         1.002   1.015   1.071   0.938   0.956   1.055   1.066   1.086   1.172
515   E         1.002   1.015   1.071   0.941   0.962   1.057   1.066   1.086   1.172
516   T        -0.134  -0.055  -0.032  -0.221  -0.088  -0.087  -0.451  -0.320  -0.325
517   Y         0.380   0.291   0.065   0.686   0.580   0.235   0.392   0.257  -0.147
518   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
519   G        -0.134  -0.079  -0.039  -0.317  -0.234  -0.179  -0.451  -0.364  -0.337
520   E        -0.720  -0.710  -0.669  -0.906  -0.874  -0.769  -0.957  -0.928  -0.833
521   E         0.057   0.082  -0.022  -0.034   0.003  -0.192  -0.114  -0.080  -0.305
522   E         0.057   0.115  -0.015  -0.002   0.086  -0.167  -0.114  -0.024  -0.293
523   D        -1.270  -1.340  -1.179  -1.349  -1.482  -1.240  -1.294  -1.356  -1.143
524   A        -1.716  -1.625  -1.525  -1.776  -1.640  -1.494  -1.547  -1.448  -1.286
525   V        -1.716  -1.701  -1.547  -1.763  -1.747  -1.507  -1.547  -1.513  -1.303
526   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
527   D         1.002   1.015   1.071   0.984   1.002   1.095   1.066   1.086   1.172
528   E        -0.419  -0.439  -0.656  -0.362  -0.397  -0.734  -0.467  -0.511  -0.807
529   T        -2.369  -2.222  -2.093  -2.242  -2.060  -1.876  -1.800  -1.681  -1.481
530   M        -1.166  -0.995  -1.126  -1.201  -0.991  -1.120  -1.210  -1.020  -1.091
531   A        -0.787  -0.840  -1.105  -0.693  -0.771  -1.157  -0.704  -0.773  -1.063
532   P         0.380   0.348   0.067   0.554   0.514   0.061   0.392   0.343  -0.142
533   Q        -0.134  -0.160  -0.059  -0.334  -0.401  -0.254  -0.451  -0.514  -0.376
534   N        -1.163  -0.913  -1.124  -1.123  -0.731  -1.108  -1.174  -0.873  -1.084
535   A        -1.355  -1.361  -1.183  -1.464  -1.474  -1.193  -1.388  -1.376  -1.146
536   G         0.330   0.197   0.041   0.471   0.292   0.026   0.320   0.111  -0.189
537   N        -1.166  -1.236  -1.149  -1.183  -1.268  -1.128  -1.210  -1.262  -1.114
538   T        -1.166  -1.127  -1.142  -1.221  -1.185  -1.183  -1.210  -1.167  -1.108
539   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
540   G        -0.512  -0.635  -0.673  -0.430  -0.640  -0.723  -0.620  -0.805  -0.834
541   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
542   G         1.002   1.015   1.071   1.047   1.062   1.152   1.066   1.086   1.172
543   S        -2.265  -2.292  -2.104  -1.991  -2.058  -1.780  -1.716  -1.722  -1.487
544   N        -1.991  -2.062  -1.851  -1.839  -1.935  -1.651  -1.632  -1.662  -1.412
545   V        -1.215  -1.257  -1.187  -1.160  -1.257  -1.145  -1.210  -1.272  -1.150
546   N        -0.914  -1.147  -1.160  -0.709  -1.044  -1.091  -0.854  -1.131  -1.122
547   Q        -0.218  -0.339  -0.615  -0.085  -0.246  -0.713  -0.198  -0.363  -0.752
548   Q        -0.218  -0.414  -0.623  -0.062  -0.321  -0.666  -0.198  -0.463  -0.762
549   -         0.198   0.187   0.034   0.211   0.196  -0.087   0.118   0.094  -0.203
550   -        -0.134  -0.048  -0.014  -0.271  -0.124  -0.100  -0.451  -0.307  -0.291
551   -        -1.783  -1.757  -1.557  -1.806  -1.785  -1.509  -1.589  -1.553  -1.311
552   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
553   N        -0.670  -0.730  -0.678  -0.749  -0.811  -0.734  -0.873  -0.929  -0.842
554   F         1.002   1.015   1.071   1.157   1.175   1.249   1.066   1.086   1.172
555   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
556   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
557   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
558   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
559   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
560   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
561   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
562   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
563   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
564   N        -0.790  -0.741  -0.690  -0.774  -0.663  -0.616  -1.024  -0.945  -0.855
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q02821
Output conservation file - output/Q02821
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
