1     M         1.772   1.773   1.789   2.054   2.060   2.082   1.902   1.904   1.923
2     A        -0.091  -0.090  -0.075  -0.266  -0.264  -0.239  -0.280  -0.278  -0.254
3     R        -0.091  -0.090  -0.075  -0.077  -0.075  -0.050  -0.280  -0.278  -0.254
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     D         1.772   1.773   1.789   1.941   1.946   1.969   1.902   1.904   1.923
6     I        -0.091  -0.090  -0.075  -0.151  -0.149  -0.125  -0.280  -0.278  -0.254
7     T        -0.091  -0.090  -0.075  -0.373  -0.372  -0.347  -0.280  -0.278  -0.254
8     F        -0.091  -0.090  -0.075  -0.021  -0.019   0.005  -0.280  -0.278  -0.254
9     L         1.772   1.773   1.789   1.548   1.553   1.575   1.902   1.904   1.923
10    T        -0.091  -0.090  -0.075  -0.413  -0.411  -0.387  -0.280  -0.278  -0.254
11    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    D        -0.091  -0.090  -0.075  -0.049  -0.047  -0.023  -0.280  -0.278  -0.254
23    E        -0.091  -0.090  -0.075  -0.237  -0.235  -0.210  -0.280  -0.278  -0.254
24    A        -0.091  -0.090  -0.075  -0.058  -0.056  -0.032  -0.280  -0.278  -0.254
25    G         1.772   1.773   1.789   2.004   2.010   2.032   1.902   1.904   1.923
26    K        -0.091  -0.090  -0.075  -0.218  -0.216  -0.191  -0.280  -0.278  -0.254
27    L        -0.091  -0.090  -0.075  -0.353  -0.352  -0.327  -0.280  -0.278  -0.254
28    L        -0.091  -0.090  -0.075  -0.494  -0.492  -0.468  -0.280  -0.278  -0.254
29    S         1.772   1.773   1.789   1.494   1.498   1.521   1.902   1.904   1.923
30    A        -0.091  -0.090  -0.075  -0.058  -0.056  -0.032  -0.280  -0.278  -0.254
31    W         1.772   1.773   1.789   2.141   2.147   2.169   1.902   1.904   1.923
32    T        -0.091  -0.090  -0.075  -0.142  -0.140  -0.116  -0.280  -0.278  -0.254
33    S        -0.091  -0.090  -0.075  -0.199  -0.197  -0.172  -0.280  -0.278  -0.254
34    T        -0.091  -0.090  -0.075  -0.199  -0.197  -0.172  -0.280  -0.278  -0.254
35    V        -0.091  -0.090  -0.075  -0.275  -0.273  -0.249  -0.280  -0.278  -0.254
36    R        -0.091  -0.090  -0.075  -0.040  -0.038  -0.013  -0.280  -0.278  -0.254
37    I        -0.091  -0.090  -0.075  -0.494  -0.492  -0.468  -0.280  -0.278  -0.254
38    E        -0.091  -0.090  -0.075   0.015   0.017   0.041  -0.280  -0.278  -0.254
39    G        -0.091  -0.090  -0.075   0.166   0.169   0.193  -0.280  -0.278  -0.254
40    P        -0.091  -0.090  -0.075  -0.324  -0.322  -0.298  -0.280  -0.278  -0.254
41    E        -0.091  -0.090  -0.075  -0.237  -0.235  -0.210  -0.280  -0.278  -0.254
42    S        -0.091  -0.090  -0.075  -0.344  -0.342  -0.317  -0.280  -0.278  -0.254
43    T        -0.091  -0.090  -0.075  -0.295  -0.293  -0.268  -0.280  -0.278  -0.254
44    D        -0.091  -0.090  -0.075   0.122   0.125   0.149  -0.280  -0.278  -0.254
45    S        -0.091  -0.090  -0.075  -0.433  -0.432  -0.407  -0.280  -0.278  -0.254
46    N        -0.091  -0.090  -0.075  -0.049  -0.047  -0.023  -0.280  -0.278  -0.254
47    S        -0.091  -0.090  -0.075  -0.227  -0.225  -0.201  -0.280  -0.278  -0.254
48    L        -0.091  -0.090  -0.075  -0.494  -0.492  -0.468  -0.280  -0.278  -0.254
49    Y        -0.091  -0.090  -0.075  -0.003  -0.001   0.023  -0.280  -0.278  -0.254
50    I         1.772   1.773   1.789   1.655   1.660   1.683   1.902   1.904   1.923
51    P         1.772   1.773   1.789   1.928   1.934   1.956   1.902   1.904   1.923
52    L        -0.091  -0.090  -0.075  -0.618  -0.617  -0.592  -0.280  -0.278  -0.254
53    L        -0.091  -0.090  -0.075  -0.494  -0.492  -0.468  -0.280  -0.278  -0.254
54    P        -0.091  -0.090  -0.075  -0.132  -0.130  -0.106  -0.280  -0.278  -0.254
55    P         1.772   1.773   1.789   1.928   1.934   1.956   1.902   1.904   1.923
56    G        -0.091  -0.090  -0.075   0.096   0.098   0.122  -0.280  -0.278  -0.254
57    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    D        -0.091  -0.090  -0.075  -0.314  -0.312  -0.288  -0.280  -0.278  -0.254
69    R         1.772   1.773   1.789   2.004   2.010   2.032   1.902   1.904   1.923
70    L        -0.091  -0.090  -0.075  -0.373  -0.372  -0.347  -0.280  -0.278  -0.254
71    V         1.772   1.773   1.789   1.839   1.844   1.866   1.902   1.904   1.923
72    T        -0.091  -0.090  -0.075  -0.295  -0.293  -0.268  -0.280  -0.278  -0.254
73    E        -0.091  -0.090  -0.075  -0.199  -0.197  -0.172  -0.280  -0.278  -0.254
74    E        -0.091  -0.090  -0.075  -0.314  -0.312  -0.288  -0.280  -0.278  -0.254
75    Q        -0.091  -0.090  -0.075  -0.151  -0.149  -0.125  -0.280  -0.278  -0.254
76    E        -0.091  -0.090  -0.075  -0.058  -0.056  -0.032  -0.280  -0.278  -0.254
77    L         1.772   1.773   1.789   1.548   1.553   1.575   1.902   1.904   1.923
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    F         1.772   1.773   1.789   1.813   1.818   1.840   1.902   1.904   1.923
83    T        -0.091  -0.090  -0.075  -0.086  -0.084  -0.060  -0.280  -0.278  -0.254
84    K         1.772   1.773   1.789   1.761   1.766   1.788   1.902   1.904   1.923
85    L        -0.091  -0.090  -0.075  -0.494  -0.492  -0.468  -0.280  -0.278  -0.254
86    R        -0.091  -0.090  -0.075  -0.040  -0.038  -0.013  -0.280  -0.278  -0.254
87    E        -0.091  -0.090  -0.075  -0.132  -0.130  -0.106  -0.280  -0.278  -0.254
88    I        -0.091  -0.090  -0.075  -0.535  -0.534  -0.509  -0.280  -0.278  -0.254
89    V        -0.091  -0.090  -0.075  -0.161  -0.159  -0.134  -0.280  -0.278  -0.254
90    G        -0.091  -0.090  -0.075   0.158   0.160   0.184  -0.280  -0.278  -0.254
91    S        -0.091  -0.090  -0.075  -0.266  -0.264  -0.239  -0.280  -0.278  -0.254
92    S         1.772   1.773   1.789   1.494   1.498   1.521   1.902   1.904   1.923
93    I        -0.091  -0.090  -0.075  -0.151  -0.149  -0.125  -0.280  -0.278  -0.254
94    R        -0.091  -0.090  -0.075   0.042   0.044   0.068  -0.280  -0.278  -0.254
95    F         1.772   1.773   1.789   1.813   1.818   1.840   1.902   1.904   1.923
96    W         1.772   1.773   1.789   2.141   2.147   2.169   1.902   1.904   1.923
97    E         1.772   1.773   1.789   1.787   1.792   1.814   1.902   1.904   1.923
98    E        -0.091  -0.090  -0.075  -0.237  -0.235  -0.210  -0.280  -0.278  -0.254
99    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   L         0.061   0.073   0.030  -0.035  -0.031  -0.069  -0.037  -0.019  -0.087
101   F        -1.181  -1.179  -1.166  -0.903  -0.939  -0.877  -1.007  -1.004  -0.980
102   Y         1.772   1.773   1.789   1.975   1.944   2.003   1.902   1.904   1.923
103   Q        -1.181  -1.179  -1.166  -0.891  -0.933  -0.865  -1.007  -1.004  -0.980
104   V         0.061   0.038   0.012  -0.054  -0.132  -0.162  -0.037  -0.073  -0.114
105   Q        -1.181  -1.179  -1.166  -0.996  -1.032  -0.970  -1.007  -1.004  -0.980
106   D        -1.181  -1.179  -1.166  -0.891  -0.874  -0.865  -1.007  -1.004  -0.980
107   V        -1.181  -1.179  -1.166  -1.209  -1.216  -1.183  -1.007  -1.004  -0.980
108   S        -1.181  -1.179  -1.166  -1.395  -1.400  -1.369  -1.007  -1.004  -0.980
109   T         0.061   0.038   0.012   0.063   0.008  -0.018  -0.037  -0.073  -0.114
110   I         0.061   0.076   0.027  -0.319  -0.289  -0.377  -0.037  -0.013  -0.091
111   E         0.061   0.076   0.027   0.200   0.269   0.139  -0.037  -0.013  -0.091
112   N         0.061   0.038   0.012   0.014  -0.081  -0.095  -0.037  -0.073  -0.114
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   H        -0.091  -0.090  -0.075   0.196   0.214   0.222  -0.280  -0.278  -0.254
115   V         0.061   0.038   0.012   0.120   0.064   0.039  -0.037  -0.073  -0.114
116   I        -1.181  -1.179  -1.166  -1.380  -1.330  -1.355  -1.007  -1.004  -0.980
117   L        -1.181  -1.179  -1.166  -0.873  -0.856  -0.847  -1.007  -1.004  -0.980
118   S        -1.181  -1.179  -1.166  -1.209  -1.163  -1.183  -1.007  -1.004  -0.980
119   L         1.772   1.773   1.789   1.544   1.534   1.572   1.902   1.904   1.923
120   K         0.061   0.038   0.012   0.242   0.215   0.177  -0.037  -0.073  -0.114
121   C         1.772   1.773   1.789   2.096   2.095   2.124   1.902   1.904   1.923
122   T        -1.181  -1.179  -1.166  -1.028  -1.048  -1.002  -1.007  -1.004  -0.980
123   I         0.061   0.038   0.012  -0.020  -0.049  -0.090  -0.037  -0.073  -0.114
124   L        -1.181  -1.179  -1.166  -1.021  -0.995  -0.995  -1.007  -1.004  -0.980
125   T         0.061   0.038   0.012   0.163   0.149   0.096  -0.037  -0.073  -0.114
126   D        -1.181  -1.179  -1.166  -0.903  -0.921  -0.877  -1.007  -1.004  -0.980
127   A        -1.181  -1.179  -1.166  -0.783  -0.804  -0.757  -1.007  -1.004  -0.980
128   Q        -1.181  -1.179  -1.166  -0.928  -0.936  -0.902  -1.007  -1.004  -0.980
129   I        -1.181  -1.179  -1.166  -1.015  -0.981  -0.989  -1.007  -1.004  -0.980
130   S        -1.181  -1.179  -1.166  -1.163  -1.091  -1.137  -1.007  -1.004  -0.980
131   T         0.061   0.038   0.012  -0.069  -0.124  -0.170  -0.037  -0.073  -0.114
132   F         0.061   0.076   0.027  -0.144  -0.127  -0.193  -0.037  -0.013  -0.091
133   I        -1.181  -1.179  -1.166  -1.196  -1.165  -1.170  -1.007  -1.004  -0.980
134   S        -1.181  -1.179  -1.166  -1.229  -1.172  -1.204  -1.007  -1.004  -0.980
135   K         0.061   0.073   0.030   0.096   0.123   0.041  -0.037  -0.019  -0.087
136   P         0.061   0.073   0.030   0.014   0.040  -0.057  -0.037  -0.019  -0.087
137   R         0.061   0.038   0.012   0.324   0.309   0.254  -0.037  -0.073  -0.114
138   E         0.061   0.038   0.012  -0.084  -0.068  -0.191  -0.037  -0.073  -0.114
139   L        -1.181  -1.179  -1.166  -1.297  -1.315  -1.271  -1.007  -1.004  -0.980
140   H        -1.181  -1.179  -1.166  -1.111  -1.104  -1.085  -1.007  -1.004  -0.980
141   T        -1.181  -1.179  -1.166  -1.209  -1.210  -1.183  -1.007  -1.004  -0.980
142   H         0.061   0.073   0.030   0.437   0.481   0.388  -0.037  -0.019  -0.087
143   A         0.061   0.038   0.012   0.292   0.263   0.212  -0.037  -0.073  -0.114
144   K        -1.181  -1.179  -1.166  -0.965  -0.981  -0.939  -1.007  -1.004  -0.980
145   G        -1.181  -1.179  -1.166  -0.953  -0.906  -0.927  -1.007  -1.004  -0.980
146   Y        -1.181  -1.179  -1.166  -0.873  -0.881  -0.847  -1.007  -1.004  -0.980
147   P         0.061   0.038   0.012   0.091   0.067  -0.006  -0.037  -0.073  -0.114
148   E         0.061   0.073   0.030  -0.084   0.002  -0.154  -0.037  -0.019  -0.087
149   I         0.061   0.076   0.027   0.024   0.036  -0.042  -0.037  -0.013  -0.091
150   Y        -1.181  -1.179  -1.166  -0.922  -0.891  -0.896  -1.007  -1.004  -0.980
151   Y        -1.181  -1.179  -1.166  -1.021  -1.065  -0.995  -1.007  -1.004  -0.980
152   L         0.061   0.038   0.012  -0.144  -0.184  -0.215  -0.037  -0.073  -0.114
153   S        -1.181  -1.179  -1.166  -1.229  -1.172  -1.204  -1.007  -1.004  -0.980
154   E         0.061   0.038   0.012   0.087   0.117   0.006  -0.037  -0.073  -0.114
155   L         0.061   0.038   0.012  -0.154  -0.218  -0.227  -0.037  -0.073  -0.114
156   S        -1.181  -1.179  -1.166  -1.236  -1.286  -1.210  -1.007  -1.004  -0.980
157   T         0.061   0.076   0.027  -0.089  -0.040  -0.144  -0.037  -0.013  -0.091
158   T        -1.181  -1.179  -1.166  -1.318  -1.340  -1.292  -1.007  -1.004  -0.980
159   V         0.061   0.038   0.012   0.177   0.116   0.104  -0.037  -0.073  -0.114
160   N         0.061   0.073   0.030   0.219   0.176   0.168  -0.037  -0.019  -0.087
161   F         0.061   0.073   0.030  -0.000   0.031  -0.067  -0.037  -0.019  -0.087
162   F        -1.181  -1.179  -1.166  -0.837  -0.848  -0.811  -1.007  -1.004  -0.980
163   S        -1.181  -1.179  -1.166  -1.256  -1.283  -1.231  -1.007  -1.004  -0.980
164   K         0.061   0.076   0.027   0.181   0.168   0.123  -0.037  -0.013  -0.091
165   E        -1.181  -1.179  -1.166  -1.150  -1.081  -1.124  -1.007  -1.004  -0.980
166   G        -1.181  -1.179  -1.166  -0.891  -0.860  -0.865  -1.007  -1.004  -0.980
167   N         0.061   0.076   0.027   0.153   0.165   0.100  -0.037  -0.013  -0.091
168   Y        -1.181  -1.179  -1.166  -1.373  -1.421  -1.348  -1.007  -1.004  -0.980
169   V        -1.181  -1.179  -1.166  -1.409  -1.415  -1.383  -1.007  -1.004  -0.980
170   E         0.061   0.076   0.027   0.200   0.269   0.139  -0.037  -0.013  -0.091
171   I         1.772   1.773   1.789   1.642   1.674   1.669   1.902   1.904   1.923
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   S         0.061   0.038   0.012  -0.366  -0.424  -0.457  -0.037  -0.073  -0.114
174   Q        -1.181  -1.179  -1.166  -0.783  -0.795  -0.757  -1.007  -1.004  -0.980
175   V        -1.181  -1.179  -1.166  -1.163  -1.157  -1.137  -1.007  -1.004  -0.980
176   I         0.061   0.073   0.030   0.063   0.101   0.027  -0.037  -0.019  -0.087
177   P        -1.181  -1.179  -1.166  -1.189  -1.216  -1.164  -1.007  -1.004  -0.980
178   H         0.061   0.038   0.012   0.383   0.331   0.298  -0.037  -0.073  -0.114
179   F         0.061   0.038   0.012   0.251   0.231   0.185  -0.037  -0.073  -0.114
180   N         1.772   1.773   1.789   1.904   1.861   1.931   1.902   1.904   1.923
181   E         1.772   1.773   1.789   1.800   1.875   1.828   1.902   1.904   1.923
182   Y         1.772   1.773   1.789   1.975   1.944   2.003   1.902   1.904   1.923
183   F         0.061   0.038   0.012   0.129   0.093   0.046  -0.037  -0.073  -0.114
184   S        -1.181  -1.179  -1.166  -1.359  -1.370  -1.334  -1.007  -1.004  -0.980
185   S         1.772   1.773   1.789   1.468   1.463   1.495   1.902   1.904   1.923
186   L         0.061   0.073   0.030  -0.246  -0.227  -0.302  -0.037  -0.019  -0.087
187   I        -1.181  -1.179  -1.166  -1.345  -1.318  -1.320  -1.007  -1.004  -0.980
188   V         0.061   0.038   0.012   0.024  -0.032  -0.072  -0.037  -0.073  -0.114
189   S         1.772   1.773   1.789   1.468   1.463   1.495   1.902   1.904   1.923
190   Q         1.772   1.773   1.789   1.924   1.887   1.952   1.902   1.904   1.923
191   L         1.772   1.773   1.789   1.544   1.534   1.572   1.902   1.904   1.923
192   E         1.772   1.773   1.789   1.800   1.875   1.828   1.902   1.904   1.923
193   F         1.772   1.773   1.789   1.852   1.874   1.880   1.902   1.904   1.923
194   E        -1.181  -1.179  -1.166  -1.002  -0.943  -0.977  -1.007  -1.004  -0.980
195   Y        -1.181  -1.179  -1.166  -1.130  -1.160  -1.104  -1.007  -1.004  -0.980
196   P         1.772   1.773   1.789   1.904   1.915   1.931   1.902   1.904   1.923
197   M         0.061   0.076   0.027  -0.035  -0.027  -0.072  -0.037  -0.013  -0.091
198   V         1.772   1.773   1.789   1.832   1.806   1.859   1.902   1.904   1.923
199   F         1.772   1.773   1.789   1.852   1.874   1.880   1.902   1.904   1.923
200   S         1.772   1.773   1.789   1.468   1.463   1.495   1.902   1.904   1.923
201   M        -1.181  -1.179  -1.166  -0.783  -0.801  -0.757  -1.007  -1.004  -0.980
202   I        -1.181  -1.179  -1.166  -0.996  -0.940  -0.970  -1.007  -1.004  -0.980
203   S        -1.181  -1.179  -1.166  -1.223  -1.226  -1.197  -1.007  -1.004  -0.980
204   R         1.772   1.773   1.789   1.945   1.968   1.972   1.902   1.904   1.923
205   L        -1.181  -1.179  -1.166  -1.510  -1.532  -1.484  -1.007  -1.004  -0.980
206   R         1.772   1.773   1.789   1.945   1.968   1.972   1.902   1.904   1.923
207   L         1.772   1.773   1.789   1.544   1.534   1.572   1.902   1.904   1.923
208   K         0.061   0.073   0.030   0.172   0.208   0.124  -0.037  -0.019  -0.087
209   W        -1.181  -1.179  -1.166  -0.725  -0.717  -0.699  -1.007  -1.004  -0.980
210   Q         0.061   0.038   0.012   0.311   0.244   0.242  -0.037  -0.073  -0.114
211   Q         0.061   0.076   0.027   0.125   0.194   0.073  -0.037  -0.013  -0.091
212   S        -1.181  -1.179  -1.166  -1.098  -1.058  -1.072  -1.007  -1.004  -0.980
213   S         0.061   0.073   0.030  -0.190  -0.204  -0.230  -0.037  -0.019  -0.087
214   L         0.061   0.076   0.027  -0.200  -0.152  -0.267  -0.037  -0.013  -0.091
215   A         0.061   0.038   0.012   0.338   0.326   0.265  -0.037  -0.073  -0.114
216   P         0.061   0.038   0.012   0.048   0.002  -0.056  -0.037  -0.073  -0.114
217   I         0.061   0.038   0.012  -0.064  -0.089  -0.140  -0.037  -0.073  -0.114
218   S         1.772   1.773   1.789   1.468   1.463   1.495   1.902   1.904   1.923
219   Y         0.061   0.038   0.012   0.246   0.179   0.160  -0.037  -0.073  -0.114
220   A         0.061   0.038   0.012   0.361   0.326   0.290  -0.037  -0.073  -0.114
221   L         1.772   1.773   1.789   1.544   1.534   1.572   1.902   1.904   1.923
222   T        -1.181  -1.179  -1.166  -1.243  -1.233  -1.217  -1.007  -1.004  -0.980
223   S         0.061   0.076   0.027   0.014  -0.004  -0.063  -0.037  -0.013  -0.091
224   N         0.061   0.076   0.027  -0.190  -0.199  -0.234  -0.037  -0.013  -0.091
225   S         0.061   0.038   0.012  -0.179  -0.241  -0.243  -0.037  -0.073  -0.114
226   V        -1.181  -1.179  -1.166  -1.002  -1.023  -0.977  -1.007  -1.004  -0.980
227   L         0.061   0.038   0.012  -0.154  -0.218  -0.227  -0.037  -0.073  -0.114
228   L        -1.181  -1.179  -1.166  -1.111  -1.119  -1.085  -1.007  -1.004  -0.980
229   P         0.061   0.073   0.030   0.048   0.070  -0.020  -0.037  -0.019  -0.087
230   I        -1.181  -1.179  -1.166  -1.332  -1.318  -1.306  -1.007  -1.004  -0.980
231   M        -1.181  -1.179  -1.166  -1.196  -1.190  -1.170  -1.007  -1.004  -0.980
232   L         0.061   0.076   0.027  -0.020  -0.026  -0.091  -0.037  -0.013  -0.091
233   N        -1.181  -1.179  -1.166  -1.229  -1.254  -1.204  -1.007  -1.004  -0.980
234   M         0.061   0.076   0.027   0.053   0.100   0.013  -0.037  -0.013  -0.091
235   I         0.061   0.073   0.030   0.053   0.095   0.016  -0.037  -0.019  -0.087
236   A        -1.181  -1.179  -1.166  -1.209  -1.179  -1.183  -1.007  -1.004  -0.980
237   Q        -1.181  -1.179  -1.166  -0.953  -1.000  -0.927  -1.007  -1.004  -0.980
238   D         0.061   0.073   0.030   0.256   0.268   0.205  -0.037  -0.019  -0.087
239   K         0.061   0.073   0.030   0.153   0.183   0.103  -0.037  -0.019  -0.087
240   S         0.061   0.076   0.027  -0.104  -0.082  -0.178  -0.037  -0.013  -0.091
241   S         0.061   0.073   0.030  -0.190  -0.204  -0.230  -0.037  -0.019  -0.087
242   T         1.772   1.773   1.789   1.779   1.780   1.807   1.902   1.904   1.923
243   T         1.772   1.773   1.789   1.779   1.780   1.807   1.902   1.904   1.923
244   A        -1.181  -1.179  -1.166  -1.085  -1.085  -1.059  -1.007  -1.004  -0.980
245   Y         0.061   0.038   0.012   0.251   0.188   0.165  -0.037  -0.073  -0.114
246   Q         1.772   1.773   1.789   1.924   1.887   1.952   1.902   1.904   1.923
247   I         0.061   0.073   0.030  -0.200  -0.159  -0.263  -0.037  -0.019  -0.087
248   L         0.061   0.073   0.030  -0.246  -0.227  -0.302  -0.037  -0.019  -0.087
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   C         0.061   0.076   0.027   0.186   0.201   0.144  -0.037  -0.013  -0.091
252   R        -1.181  -1.179  -1.166  -1.117  -1.144  -1.091  -1.007  -1.004  -0.980
253   R         0.061   0.038   0.012   0.219   0.201   0.133  -0.037  -0.073  -0.114
254   R        -1.181  -1.179  -1.166  -1.015  -1.002  -0.989  -1.007  -1.004  -0.980
255   G        -1.181  -1.179  -1.166  -0.795  -0.751  -0.769  -1.007  -1.004  -0.980
256   P        -1.181  -1.179  -1.166  -0.885  -0.905  -0.859  -1.007  -1.004  -0.980
257   P        -1.181  -1.179  -1.166  -1.066  -1.023  -1.040  -1.007  -1.004  -0.980
258   I        -1.181  -1.179  -1.166  -1.359  -1.375  -1.334  -1.007  -1.004  -0.980
259   Q        -0.091  -0.090  -0.075  -0.132  -0.130  -0.106  -0.280  -0.278  -0.254
260   N        -0.091  -0.090  -0.075  -0.180  -0.178  -0.153  -0.280  -0.278  -0.254
261   F         0.061   0.076   0.027   0.251   0.251   0.192  -0.037  -0.013  -0.091
262   Q         0.061   0.076   0.027   0.163   0.177   0.110  -0.037  -0.013  -0.091
263   I        -1.181  -1.179  -1.166  -1.607  -1.607  -1.581  -1.007  -1.004  -0.980
264   F        -1.181  -1.179  -1.166  -0.990  -1.006  -0.964  -1.007  -1.004  -0.980
265   S        -1.181  -1.179  -1.166  -1.189  -1.215  -1.164  -1.007  -1.004  -0.980
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   L         1.772   1.773   1.789   1.544   1.534   1.572   1.902   1.904   1.923
271   P         1.772   1.773   1.789   1.928   1.934   1.956   1.902   1.904   1.923
272   A        -0.091  -0.090  -0.075   0.024   0.026   0.050  -0.280  -0.278  -0.254
273   V        -0.091  -0.090  -0.075   0.015   0.017   0.041  -0.280  -0.278  -0.254
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   T         1.772   1.773   1.789   1.813   1.818   1.840   1.902   1.904   1.923
278   Y        -0.091  -0.090  -0.075   0.069   0.071   0.095  -0.280  -0.278  -0.254
279   N        -1.181  -1.179  -1.166  -0.940  -0.955  -0.914  -1.007  -1.004  -0.980
280   K        -1.181  -1.179  -1.166  -1.098  -1.062  -1.072  -1.007  -1.004  -0.980
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q02721
Output conservation file - output/Q02721
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
