1     M         1.790   1.791   1.809   2.020   2.021   2.052   1.918   1.920   1.943
2     S         0.142   0.131   0.108  -0.057  -0.075  -0.106   0.021   0.004  -0.033
3     K         0.142   0.128   0.101   0.016  -0.000  -0.032   0.021  -0.001  -0.045
4     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     E         1.790   1.791   1.809   1.668   1.670   1.699   1.918   1.920   1.943
6     T         1.790   1.791   1.809   1.900   1.902   1.931   1.918   1.920   1.943
7     V         0.142   0.131   0.108   0.196   0.176   0.139   0.021   0.004  -0.033
8     Y         1.790   1.791   1.809   1.973   1.977   2.005   1.918   1.920   1.943
9     L         0.142   0.170   0.117   0.136   0.184   0.087   0.021   0.065  -0.020
10    Y         1.790   1.791   1.809   1.942   1.944   1.973   1.918   1.920   1.943
11    A         0.142   0.128   0.101   0.259   0.233   0.192   0.021  -0.001  -0.045
12    G         1.790   1.791   1.809   2.034   2.035   2.065   1.918   1.920   1.943
13    E         1.790   1.791   1.809   1.711   1.713   1.742   1.918   1.920   1.943
14    E         0.142   0.170   0.117   0.032   0.082  -0.013   0.021   0.065  -0.020
15    Q        -1.054  -1.053  -1.041  -0.920  -0.919  -0.897  -0.928  -0.926  -0.903
16    P         0.142   0.128   0.101   0.255   0.230   0.176   0.021  -0.001  -0.045
17    R        -1.054  -1.053  -1.041  -1.070  -1.074  -1.047  -0.928  -0.926  -0.903
18    V         1.790   1.791   1.809   1.850   1.850   1.882   1.918   1.920   1.943
19    K        -1.054  -1.053  -1.041  -1.159  -1.150  -1.137  -0.928  -0.926  -0.903
20    L         1.790   1.791   1.809   1.697   1.700   1.728   1.918   1.920   1.943
21    T         0.142   0.128   0.101   0.078   0.051  -0.007   0.021  -0.001  -0.045
22    C        -1.054  -1.053  -1.041  -0.874  -0.878  -0.851  -0.928  -0.926  -0.903
23    I         0.142   0.128   0.101   0.187   0.163   0.119   0.021  -0.001  -0.045
24    K         0.142   0.128   0.101  -0.148  -0.168  -0.217   0.021  -0.001  -0.045
25    E        -1.054  -1.053  -1.041  -1.039  -1.034  -1.017  -0.928  -0.926  -0.903
26    G        -1.054  -1.053  -1.041  -0.645  -0.646  -0.621  -0.928  -0.926  -0.903
27    L        -1.054  -1.053  -1.041  -1.009  -1.003  -0.986  -0.928  -0.926  -0.903
28    T        -1.054  -1.053  -1.041  -0.890  -0.891  -0.867  -0.928  -0.926  -0.903
29    L        -1.054  -1.053  -1.041  -1.191  -1.189  -1.169  -0.928  -0.926  -0.903
30    T        -1.054  -1.053  -1.041  -1.182  -1.185  -1.160  -0.928  -0.926  -0.903
31    Q         0.142   0.170   0.117   0.120   0.162   0.085   0.021   0.065  -0.020
32    V        -1.054  -1.053  -1.041  -1.013  -1.014  -0.991  -0.928  -0.926  -0.903
33    I         0.142   0.128   0.101   0.187   0.163   0.119   0.021  -0.001  -0.045
34    K        -1.054  -1.053  -1.041  -1.146  -1.135  -1.123  -0.928  -0.926  -0.903
35    F         0.142   0.170   0.117   0.339   0.386   0.297   0.021   0.065  -0.020
36    V        -1.054  -1.053  -1.041  -0.970  -0.970  -0.947  -0.928  -0.926  -0.903
37    H         0.142   0.128   0.101   0.459   0.438   0.401   0.021  -0.001  -0.045
38    S        -1.054  -1.053  -1.041  -0.941  -0.931  -0.918  -0.928  -0.926  -0.903
39    I         0.142   0.131   0.108   0.265   0.249   0.218   0.021   0.004  -0.033
40    Q         1.790   1.791   1.809   1.939   1.944   1.971   1.918   1.920   1.943
41    E         0.142   0.170   0.117   0.136   0.182   0.088   0.021   0.065  -0.020
42    L        -1.054  -1.053  -1.041  -1.177  -1.176  -1.155  -0.928  -0.926  -0.903
43    Y        -1.054  -1.053  -1.041  -0.784  -0.785  -0.760  -0.928  -0.926  -0.903
44    G        -1.054  -1.053  -1.041  -0.645  -0.645  -0.621  -0.928  -0.926  -0.903
45    I        -1.054  -1.053  -1.041  -1.013  -1.013  -0.991  -0.928  -0.926  -0.903
46    E        -1.054  -1.053  -1.041  -1.123  -1.118  -1.101  -0.928  -0.926  -0.903
47    L         0.142   0.128   0.101   0.088   0.068   0.027   0.021  -0.001  -0.045
48    Q        -1.054  -1.053  -1.041  -1.013  -1.017  -0.991  -0.928  -0.926  -0.903
49    T        -1.054  -1.053  -1.041  -0.728  -0.723  -0.704  -0.928  -0.926  -0.903
50    S         0.142   0.131   0.108  -0.053  -0.071  -0.103   0.021   0.004  -0.033
51    E         1.790   1.791   1.809   1.711   1.713   1.742   1.918   1.920   1.943
52    T         1.790   1.791   1.809   1.850   1.852   1.882   1.918   1.920   1.943
53    I         1.790   1.791   1.809   1.830   1.832   1.861   1.918   1.920   1.943
54    T         0.142   0.128   0.101   0.224   0.201   0.159   0.021  -0.001  -0.045
55    E        -1.054  -1.053  -1.041  -0.882  -0.877  -0.859  -0.928  -0.926  -0.903
56    N         1.790   1.791   1.809   1.732   1.737   1.763   1.918   1.920   1.943
57    L         1.790   1.791   1.809   1.697   1.700   1.728   1.918   1.920   1.943
58    K         1.790   1.791   1.809   1.547   1.551   1.577   1.918   1.920   1.943
59    I         0.142   0.128   0.101   0.187   0.163   0.119   0.021  -0.001  -0.045
60    D        -1.054  -1.053  -1.041  -1.187  -1.191  -1.164  -0.928  -0.926  -0.903
61    C        -0.005  -0.004   0.011   0.100   0.101   0.127  -0.217  -0.216  -0.191
62    A        -0.005  -0.004   0.011   0.026   0.027   0.052  -0.217  -0.216  -0.191
63    P        -0.005  -0.004   0.011  -0.001  -0.000   0.025  -0.217  -0.216  -0.191
64    A        -1.054  -1.053  -1.041  -0.937  -0.938  -0.913  -0.928  -0.926  -0.903
65    Y         0.142   0.170   0.117   0.155   0.199   0.121   0.021   0.065  -0.020
66    L        -1.054  -1.053  -1.041  -1.177  -1.174  -1.155  -0.928  -0.926  -0.903
67    K         0.142   0.170   0.117   0.221   0.276   0.164   0.021   0.065  -0.020
68    P        -1.054  -1.053  -1.041  -1.013  -1.018  -0.991  -0.928  -0.926  -0.903
69    N        -1.054  -1.053  -1.041  -1.173  -1.171  -1.150  -0.928  -0.926  -0.903
70    C        -1.054  -1.053  -1.041  -0.920  -0.930  -0.897  -0.928  -0.926  -0.903
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    I        -1.054  -1.053  -1.041  -0.812  -0.809  -0.789  -0.928  -0.926  -0.903
76    P        -1.054  -1.053  -1.041  -0.907  -0.909  -0.884  -0.928  -0.926  -0.903
77    H         0.142   0.170   0.117   0.390   0.433   0.353   0.021   0.065  -0.020
78    F         1.790   1.791   1.809   1.899   1.901   1.930   1.918   1.920   1.943
79    Y         1.790   1.791   1.809   1.973   1.977   2.005   1.918   1.920   1.943
80    I         1.790   1.791   1.809   1.830   1.832   1.861   1.918   1.920   1.943
81    L         0.142   0.128   0.101   0.065   0.043   0.001   0.021  -0.001  -0.045
82    E         1.790   1.791   1.809   1.711   1.713   1.742   1.918   1.920   1.943
83    Y         0.142   0.128   0.101   0.339   0.317   0.270   0.021  -0.001  -0.045
84    E        -1.054  -1.053  -1.041  -0.903  -0.894  -0.880  -0.928  -0.926  -0.903
85    E        -1.054  -1.053  -1.041  -0.996  -0.994  -0.973  -0.928  -0.926  -0.903
86    I        -1.054  -1.053  -1.041  -1.066  -1.068  -1.043  -0.928  -0.926  -0.903
87    S        -1.054  -1.053  -1.041  -1.173  -1.167  -1.150  -0.928  -0.926  -0.903
88    D         0.142   0.128   0.101   0.136   0.109   0.060   0.021  -0.001  -0.045
89    T         0.142   0.128   0.101   0.142   0.117   0.066   0.021  -0.001  -0.045
90    F         0.142   0.131   0.108   0.305   0.289   0.254   0.021   0.004  -0.033
91    F         0.142   0.170   0.117  -0.030   0.011  -0.064   0.021   0.065  -0.020
92    I        -1.054  -1.053  -1.041  -1.013  -1.013  -0.991  -0.928  -0.926  -0.903
93    W         1.790   1.791   1.809   2.087   2.089   2.119   1.918   1.920   1.943
94    K         0.142   0.128   0.101  -0.057  -0.076  -0.114   0.021  -0.001  -0.045
95    S         1.790   1.791   1.809   1.568   1.570   1.599   1.918   1.920   1.943
96    D         0.142   0.131   0.108   0.215   0.194   0.161   0.021   0.004  -0.033
97    G         0.142   0.131   0.108   0.249   0.226   0.175   0.021   0.004  -0.033
98    R        -1.054  -1.053  -1.041  -0.915  -0.915  -0.892  -0.928  -0.926  -0.903
99    W         1.790   1.791   1.809   2.087   2.089   2.119   1.918   1.920   1.943
100   Q        -1.054  -1.053  -1.041  -0.920  -0.919  -0.897  -0.928  -0.926  -0.903
101   L         0.142   0.128   0.101   0.084   0.064   0.023   0.021  -0.001  -0.045
102   N        -1.054  -1.053  -1.041  -1.159  -1.158  -1.137  -0.928  -0.926  -0.903
103   K        -1.054  -1.053  -1.041  -1.370  -1.364  -1.348  -0.928  -0.926  -0.903
104   L         0.142   0.170   0.117   0.174   0.222   0.125   0.021   0.065  -0.020
105   S        -1.054  -1.053  -1.041  -1.092  -1.084  -1.070  -0.928  -0.926  -0.903
106   A         0.142   0.128   0.101   0.243   0.218   0.174   0.021  -0.001  -0.045
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   L         0.142   0.170   0.117   0.136   0.185   0.087   0.021   0.065  -0.020
113   L         1.790   1.791   1.809   1.697   1.700   1.728   1.918   1.920   1.943
114   Y         0.142   0.128   0.101   0.390   0.370   0.329   0.021  -0.001  -0.045
115   V         0.142   0.170   0.117   0.372   0.418   0.327   0.021   0.065  -0.020
116   D        -1.054  -1.053  -1.041  -1.159  -1.163  -1.137  -0.928  -0.926  -0.903
117   N         0.142   0.128   0.101   0.174   0.156   0.119   0.021  -0.001  -0.045
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   D        -1.054  -1.053  -1.041  -1.083  -1.087  -1.061  -0.928  -0.926  -0.903
120   A         0.142   0.131   0.108   0.174   0.153   0.109   0.021   0.004  -0.033
121   N        -1.054  -1.053  -1.041  -1.168  -1.165  -1.146  -0.928  -0.926  -0.903
122   V        -1.054  -1.053  -1.041  -1.097  -1.101  -1.074  -0.928  -0.926  -0.903
123   V        -1.054  -1.053  -1.041  -1.000  -1.001  -0.978  -0.928  -0.926  -0.903
124   K         0.142   0.131   0.108  -0.014  -0.026  -0.055   0.021   0.004  -0.033
125   N        -1.054  -1.053  -1.041  -1.159  -1.159  -1.137  -0.928  -0.926  -0.903
126   T        -1.054  -1.053  -1.041  -0.890  -0.891  -0.867  -0.928  -0.926  -0.903
127   S        -0.005  -0.004   0.011  -0.255  -0.255  -0.230  -0.217  -0.216  -0.191
128   W         1.790   1.791   1.809   2.068   2.070   2.100   1.918   1.920   1.943
129   K        -0.005  -0.004   0.011  -0.241  -0.240  -0.216  -0.217  -0.216  -0.191
130   E         1.790   1.791   1.809   1.668   1.670   1.699   1.918   1.920   1.943
131   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   F         0.142   0.131   0.108   0.180   0.162   0.115   0.021   0.004  -0.033
133   Q         0.142   0.170   0.117   0.246   0.288   0.208   0.021   0.065  -0.020
134   N        -1.054  -1.053  -1.041  -0.949  -0.942  -0.926  -0.928  -0.926  -0.903
135   D        -1.054  -1.053  -1.041  -0.886  -0.886  -0.863  -0.928  -0.926  -0.903
136   Q        -1.054  -1.053  -1.041  -1.132  -1.136  -1.110  -0.928  -0.926  -0.903
137   R         0.142   0.131   0.108   0.101   0.078   0.028   0.021   0.004  -0.033
138   F        -1.054  -1.053  -1.041  -0.780  -0.779  -0.756  -0.928  -0.926  -0.903
139   K        -1.054  -1.053  -1.041  -1.214  -1.203  -1.192  -0.928  -0.926  -0.903
140   N        -1.054  -1.053  -1.041  -1.009  -1.002  -0.986  -0.928  -0.926  -0.903
141   Y         0.142   0.170   0.117   0.408   0.453   0.369   0.021   0.065  -0.020
142   D        -0.005  -0.004   0.011   0.067   0.068   0.093  -0.217  -0.216  -0.191
143   K        -0.005  -0.004   0.011  -0.381  -0.380  -0.356  -0.217  -0.216  -0.191
144   R        -1.054  -1.053  -1.041  -1.083  -1.087  -1.061  -0.928  -0.926  -0.903
145   A        -1.054  -1.053  -1.041  -0.866  -0.865  -0.842  -0.928  -0.926  -0.903
146   W        -1.054  -1.053  -1.041  -0.744  -0.749  -0.720  -0.928  -0.926  -0.903
147   L         0.142   0.131   0.108   0.065   0.048   0.013   0.021   0.004  -0.033
148   Q        -1.054  -1.053  -1.041  -0.915  -0.918  -0.892  -0.928  -0.926  -0.903
149   N         1.790   1.791   1.809   1.732   1.737   1.763   1.918   1.920   1.943
150   C        -1.054  -1.053  -1.041  -1.009  -1.020  -0.986  -0.928  -0.926  -0.903
151   L         1.790   1.791   1.809   1.697   1.700   1.728   1.918   1.920   1.943
152   E         0.142   0.170   0.117  -0.141  -0.093  -0.184   0.021   0.065  -0.020
153   K         0.142   0.131   0.108  -0.141  -0.157  -0.198   0.021   0.004  -0.033
154   M        -1.054  -1.053  -1.041  -0.866  -0.870  -0.842  -0.928  -0.926  -0.903
155   N         1.790   1.791   1.809   1.732   1.737   1.763   1.918   1.920   1.943
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   R         0.142   0.128   0.101   0.237   0.211   0.168   0.021  -0.001  -0.045
158   D         1.790   1.791   1.809   1.844   1.843   1.875   1.918   1.920   1.943
159   L        -1.054  -1.053  -1.041  -0.853  -0.843  -0.830  -0.928  -0.926  -0.903
160   S         0.142   0.131   0.108   0.029   0.014  -0.011   0.021   0.004  -0.033
161   K         0.142   0.128   0.101  -0.131  -0.150  -0.198   0.021  -0.001  -0.045
162   L        -1.054  -1.053  -1.041  -0.853  -0.842  -0.830  -0.928  -0.926  -0.903
163   N         0.142   0.131   0.108   0.094   0.078   0.041   0.021   0.004  -0.033
164   V        -0.005  -0.004   0.011  -0.035  -0.035  -0.010  -0.217  -0.216  -0.191
165   E        -0.005  -0.004   0.011  -0.388  -0.388  -0.364  -0.217  -0.216  -0.191
166   Q        -0.005  -0.004   0.011  -0.008  -0.007   0.018  -0.217  -0.216  -0.191
167   F         1.790   1.791   1.809   1.900   1.902   1.931   1.918   1.920   1.943
168   W         1.790   1.791   1.809   2.087   2.089   2.119   1.918   1.920   1.943
169   S        -0.005  -0.004   0.011  -0.495  -0.495  -0.471  -0.217  -0.216  -0.191
170   Q        -0.005  -0.004   0.011  -0.112  -0.111  -0.087  -0.217  -0.216  -0.191
171   Y        -0.005  -0.004   0.011   0.033   0.034   0.059  -0.217  -0.216  -0.191
172   D         1.790   1.791   1.809   1.844   1.843   1.875   1.918   1.920   1.943
173   K        -1.054  -1.053  -1.041  -1.355  -1.347  -1.334  -0.928  -0.926  -0.903
174   I         0.142   0.128   0.101   0.262   0.241   0.204   0.021  -0.001  -0.045
175   C         0.142   0.131   0.108   0.456   0.437   0.396   0.021   0.004  -0.033
176   Q        -1.054  -1.053  -1.041  -0.833  -0.833  -0.809  -0.928  -0.926  -0.903
177   S        -1.054  -1.053  -1.041  -1.083  -1.077  -1.061  -0.928  -0.926  -0.903
178   I        -1.054  -1.053  -1.041  -1.018  -1.018  -0.995  -0.928  -0.926  -0.903
179   A         0.142   0.131   0.108   0.320   0.302   0.272   0.021   0.004  -0.033
180   K         0.142   0.131   0.108  -0.084  -0.098  -0.133   0.021   0.004  -0.033
181   Q         0.142   0.131   0.108   0.308   0.292   0.253   0.021   0.004  -0.033
182   K        -1.054  -1.053  -1.041  -1.035  -1.023  -1.012  -0.928  -0.926  -0.903
183   K        -1.054  -1.053  -1.041  -1.370  -1.364  -1.348  -0.928  -0.926  -0.903
184   K         0.142   0.131   0.108  -0.053  -0.068  -0.100   0.021   0.004  -0.033
185   Q        -1.054  -1.053  -1.041  -0.736  -0.734  -0.712  -0.928  -0.926  -0.903
186   E         0.142   0.128   0.101   0.097   0.075   0.036   0.021  -0.001  -0.045
187   Q        -1.054  -1.053  -1.041  -0.945  -0.946  -0.922  -0.928  -0.926  -0.903
188   F        -1.054  -1.053  -1.041  -1.035  -1.037  -1.012  -0.928  -0.926  -0.903
189   N        -1.054  -1.053  -1.041  -1.355  -1.356  -1.334  -0.928  -0.926  -0.903
190   M        -1.054  -1.053  -1.041  -0.732  -0.734  -0.708  -0.928  -0.926  -0.903
191   E         0.142   0.131   0.108   0.068   0.051   0.015   0.021   0.004  -0.033
192   V        -0.005  -0.004   0.011  -0.012  -0.012   0.013  -0.217  -0.216  -0.191
193   F        -0.005  -0.004   0.011   0.058   0.059   0.084  -0.217  -0.216  -0.191
194   D        -0.005  -0.004   0.011   0.009   0.010   0.035  -0.217  -0.216  -0.191
195   N        -1.054  -1.053  -1.041  -0.949  -0.942  -0.926  -0.928  -0.926  -0.903
196   F         0.142   0.131   0.108   0.180   0.162   0.115   0.021   0.004  -0.033
197   K         0.142   0.128   0.101   0.006  -0.010  -0.043   0.021  -0.001  -0.045
198   N        -1.054  -1.053  -1.041  -0.878  -0.870  -0.855  -0.928  -0.926  -0.903
199   I         0.142   0.131   0.108   0.059   0.038  -0.012   0.021   0.004  -0.033
200   V         0.142   0.131   0.108   0.283   0.265   0.236   0.021   0.004  -0.033
201   S        -1.054  -1.053  -1.041  -1.150  -1.143  -1.128  -0.928  -0.926  -0.903
202   I         0.142   0.170   0.117   0.055   0.101   0.015   0.021   0.065  -0.020
203   A         0.142   0.131   0.108   0.117   0.094   0.045   0.021   0.004  -0.033
204   I         0.142   0.170   0.117   0.055   0.101   0.015   0.021   0.065  -0.020
205   I         0.142   0.131   0.108   0.117   0.098   0.053   0.021   0.004  -0.033
206   K         0.142   0.131   0.108  -0.057  -0.072  -0.104   0.021   0.004  -0.033
207   T        -1.054  -1.053  -1.041  -1.053  -1.055  -1.030  -0.928  -0.926  -0.903
208   K        -1.054  -1.053  -1.041  -1.070  -1.060  -1.047  -0.928  -0.926  -0.903
209   V         0.142   0.128   0.101   0.136   0.110   0.058   0.021  -0.001  -0.045
210   L        -1.054  -1.053  -1.041  -1.182  -1.181  -1.160  -0.928  -0.926  -0.903
211   S        -1.054  -1.053  -1.041  -1.380  -1.374  -1.358  -0.928  -0.926  -0.903
212   N         1.790   1.791   1.809   1.732   1.737   1.763   1.918   1.920   1.943
213   K         1.790   1.791   1.809   1.547   1.551   1.577   1.918   1.920   1.943
214   R         0.142   0.128   0.101   0.311   0.288   0.252   0.021  -0.001  -0.045
215   L        -1.054  -1.053  -1.041  -1.088  -1.084  -1.065  -0.928  -0.926  -0.903
216   L         0.142   0.128   0.101   0.055   0.035  -0.010   0.021  -0.001  -0.045
217   T        -1.054  -1.053  -1.041  -0.975  -0.975  -0.952  -0.928  -0.926  -0.903
218   T        -1.054  -1.053  -1.041  -1.155  -1.157  -1.132  -0.928  -0.926  -0.903
219   T         0.142   0.128   0.101   0.246   0.225   0.184   0.021  -0.001  -0.045
220   L         0.142   0.128   0.101   0.055   0.035  -0.010   0.021  -0.001  -0.045
221   K        -1.054  -1.053  -1.041  -1.196  -1.187  -1.173  -0.928  -0.926  -0.903
222   N        -1.054  -1.053  -1.041  -1.128  -1.125  -1.105  -0.928  -0.926  -0.903
223   Y         0.142   0.128   0.101   0.339   0.317   0.270   0.021  -0.001  -0.045
224   H         1.790   1.791   1.809   2.003   2.006   2.035   1.918   1.920   1.943
225   N        -0.005  -0.004   0.011  -0.105  -0.104  -0.080  -0.217  -0.216  -0.191
226   S        -0.005  -0.004   0.011  -0.212  -0.211  -0.187  -0.217  -0.216  -0.191
227   M         1.790   1.791   1.809   2.050   2.052   2.081   1.918   1.920   1.943
228   K        -0.005  -0.004   0.011  -0.495  -0.495  -0.471  -0.217  -0.216  -0.191
229   K        -0.005  -0.004   0.011  -0.241  -0.240  -0.216  -0.217  -0.216  -0.191
230   K         0.142   0.131   0.108  -0.077  -0.092  -0.126   0.021   0.004  -0.033
231   Y        -1.054  -1.053  -1.041  -0.736  -0.736  -0.712  -0.928  -0.926  -0.903
232   N        -1.054  -1.053  -1.041  -1.146  -1.142  -1.123  -0.928  -0.926  -0.903
233   I        -1.054  -1.053  -1.041  -0.890  -0.888  -0.867  -0.928  -0.926  -0.903
234   Q        -1.054  -1.053  -1.041  -0.736  -0.734  -0.712  -0.928  -0.926  -0.903
235   E        -1.054  -1.053  -1.041  -1.123  -1.118  -1.101  -0.928  -0.926  -0.903
236   Q        -1.054  -1.053  -1.041  -1.026  -1.032  -1.004  -0.928  -0.926  -0.903
237   N         0.142   0.128   0.101   0.113   0.093   0.051   0.021  -0.001  -0.045
238   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   K         1.790   1.791   1.809   1.529   1.531   1.559   1.918   1.920   1.943
240   E        -0.005  -0.004   0.011  -0.183  -0.182  -0.158  -0.217  -0.216  -0.191
241   N        -0.005  -0.004   0.011  -0.351  -0.350  -0.326  -0.217  -0.216  -0.191
242   S        -0.005  -0.004   0.011  -0.262  -0.262  -0.237  -0.217  -0.216  -0.191
243   L        -0.005  -0.004   0.011   0.026   0.027   0.052  -0.217  -0.216  -0.191
244   A        -0.005  -0.004   0.011  -0.140  -0.140  -0.115  -0.217  -0.216  -0.191
245   S         1.790   1.791   1.809   1.569   1.571   1.599   1.918   1.920   1.943
246   C        -0.005  -0.004   0.011   0.114   0.115   0.140  -0.217  -0.216  -0.191
247   S         1.790   1.791   1.809   1.569   1.571   1.599   1.918   1.920   1.943
248   N        -0.005  -0.004   0.011  -0.277  -0.276  -0.252  -0.217  -0.216  -0.191
249   N        -0.005  -0.004   0.011  -0.147  -0.147  -0.122  -0.217  -0.216  -0.191
250   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   E        -0.005  -0.004   0.011  -0.388  -0.388  -0.364  -0.217  -0.216  -0.191
257   S        -0.005  -0.004   0.011  -0.070  -0.069  -0.044  -0.217  -0.216  -0.191
258   E         1.790   1.791   1.809   1.668   1.670   1.699   1.918   1.920   1.943
259   S        -0.005  -0.004   0.011  -0.255  -0.255  -0.230  -0.217  -0.216  -0.191
260   R        -0.005  -0.004   0.011  -0.140  -0.140  -0.115  -0.217  -0.216  -0.191
261   H        -0.005  -0.004   0.011  -0.063  -0.062  -0.038  -0.217  -0.216  -0.191
262   F        -0.005  -0.004   0.011   0.134   0.135   0.160  -0.217  -0.216  -0.191
263   S         0.142   0.128   0.101  -0.063  -0.085  -0.125   0.021  -0.001  -0.045
264   P         0.142   0.128   0.101   0.332   0.309   0.263   0.021  -0.001  -0.045
265   V         1.790   1.791   1.809   1.850   1.850   1.882   1.918   1.920   1.943
266   N        -1.054  -1.053  -1.041  -1.132  -1.130  -1.110  -0.928  -0.926  -0.903
267   S         1.790   1.791   1.809   1.569   1.571   1.599   1.918   1.920   1.943
268   L         1.790   1.791   1.809   1.746   1.749   1.777   1.918   1.920   1.943
269   S         1.790   1.791   1.809   1.568   1.570   1.599   1.918   1.920   1.943
270   P         1.790   1.791   1.809   1.973   1.976   2.005   1.918   1.920   1.943
271   S        -1.054  -1.053  -1.041  -1.074  -1.063  -1.052  -0.928  -0.926  -0.903
272   S         1.790   1.791   1.809   1.559   1.561   1.590   1.918   1.920   1.943
273   L        -0.005  -0.004   0.011  -0.172  -0.171  -0.147  -0.217  -0.216  -0.191
274   S         1.790   1.791   1.809   1.559   1.561   1.590   1.918   1.920   1.943
275   T         1.790   1.791   1.809   1.814   1.816   1.845   1.918   1.920   1.943
276   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   Y         1.790   1.791   1.809   1.975   1.977   2.007   1.918   1.920   1.943
287   K        -0.005  -0.004   0.011  -0.241  -0.240  -0.216  -0.217  -0.216  -0.191
288   G        -0.005  -0.004   0.011   0.114   0.115   0.140  -0.217  -0.216  -0.191
289   P        -0.005  -0.004   0.011   0.107   0.108   0.133  -0.217  -0.216  -0.191
290   E        -1.054  -1.053  -1.041  -1.182  -1.179  -1.160  -0.928  -0.926  -0.903
291   S        -1.054  -1.053  -1.041  -0.949  -0.939  -0.926  -0.928  -0.926  -0.903
292   K        -1.054  -1.053  -1.041  -1.355  -1.348  -1.334  -0.928  -0.926  -0.903
293   P         0.142   0.131   0.108   0.183   0.163   0.109   0.021   0.004  -0.033
294   N         0.142   0.128   0.101   0.113   0.093   0.051   0.021  -0.001  -0.045
295   V        -1.054  -1.053  -1.041  -0.895  -0.894  -0.871  -0.928  -0.926  -0.903
296   N        -1.054  -1.053  -1.041  -0.979  -0.974  -0.956  -0.928  -0.926  -0.903
297   F         0.142   0.128   0.101   0.187   0.162   0.109   0.021  -0.001  -0.045
298   M        -1.054  -1.053  -1.041  -0.756  -0.758  -0.732  -0.928  -0.926  -0.903
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   H        -1.054  -1.053  -1.041  -0.748  -0.748  -0.724  -0.928  -0.926  -0.903
302   S        -1.054  -1.053  -1.041  -1.083  -1.076  -1.061  -0.928  -0.926  -0.903
303   S        -1.054  -1.053  -1.041  -1.048  -1.037  -1.025  -0.928  -0.926  -0.903
304   A        -1.054  -1.053  -1.041  -0.861  -0.863  -0.838  -0.928  -0.926  -0.903
305   T         0.142   0.131   0.108   0.262   0.245   0.212   0.021   0.004  -0.033
306   N         0.142   0.170   0.117  -0.110  -0.064  -0.152   0.021   0.065  -0.020
307   D        -1.054  -1.053  -1.041  -1.097  -1.099  -1.074  -0.928  -0.926  -0.903
308   L         0.142   0.170   0.117   0.218   0.271   0.168   0.021   0.065  -0.020
309   I         0.142   0.131   0.108   0.117   0.098   0.053   0.021   0.004  -0.033
310   K        -1.054  -1.053  -1.041  -0.928  -0.913  -0.905  -0.928  -0.926  -0.903
311   S         1.790   1.791   1.809   1.568   1.570   1.599   1.918   1.920   1.943
312   N         1.790   1.791   1.809   1.732   1.737   1.763   1.918   1.920   1.943
313   F         1.790   1.791   1.809   1.899   1.901   1.930   1.918   1.920   1.943
314   E         0.142   0.170   0.117   0.032   0.082  -0.013   0.021   0.065  -0.020
315   S        -1.054  -1.053  -1.041  -0.970  -0.960  -0.947  -0.928  -0.926  -0.903
316   Y        -1.054  -1.053  -1.041  -0.895  -0.896  -0.871  -0.928  -0.926  -0.903
317   F         1.790   1.791   1.809   1.899   1.901   1.930   1.918   1.920   1.943
318   K         0.142   0.131   0.108  -0.030  -0.042  -0.074   0.021   0.004  -0.033
319   L        -1.054  -1.053  -1.041  -1.097  -1.091  -1.074  -0.928  -0.926  -0.903
320   M         0.142   0.128   0.101   0.351   0.326   0.277   0.021  -0.001  -0.045
321   A         0.142   0.128   0.101   0.243   0.218   0.174   0.021  -0.001  -0.045
322   E         1.790   1.791   1.809   1.711   1.713   1.742   1.918   1.920   1.943
323   D         0.142   0.170   0.117   0.094   0.140   0.054   0.021   0.065  -0.020
324   Y         0.142   0.170   0.117   0.305   0.349   0.268   0.021   0.065  -0.020
325   E         1.790   1.791   1.809   1.711   1.713   1.742   1.918   1.920   1.943
326   T         0.142   0.128   0.101   0.202   0.178   0.134   0.021  -0.001  -0.045
327   F        -1.054  -1.053  -1.041  -0.804  -0.802  -0.781  -0.928  -0.926  -0.903
328   D         0.142   0.128   0.101   0.255   0.233   0.195   0.021  -0.001  -0.045
329   L         0.142   0.131   0.108   0.065   0.049   0.013   0.021   0.004  -0.033
330   R        -1.054  -1.053  -1.041  -0.975  -0.979  -0.952  -0.928  -0.926  -0.903
331   A        -1.054  -1.053  -1.041  -1.044  -1.048  -1.021  -0.928  -0.926  -0.903
332   W        -1.054  -1.053  -1.041  -0.641  -0.641  -0.618  -0.928  -0.926  -0.903
333   S         0.142   0.131   0.108   0.006  -0.009  -0.036   0.021   0.004  -0.033
334   R        -1.054  -1.053  -1.041  -1.251  -1.259  -1.229  -0.928  -0.926  -0.903
335   Q        -1.054  -1.053  -1.041  -0.780  -0.777  -0.756  -0.928  -0.926  -0.903
336   R         0.142   0.128   0.101   0.293   0.269   0.231   0.021  -0.001  -0.045
337   P        -1.054  -1.053  -1.041  -1.088  -1.095  -1.065  -0.928  -0.926  -0.903
338   R         0.142   0.131   0.108   0.168   0.146   0.103   0.021   0.004  -0.033
339   K         0.142   0.131   0.108  -0.057  -0.072  -0.104   0.021   0.004  -0.033
340   F        -1.054  -1.053  -1.041  -0.949  -0.950  -0.926  -0.928  -0.926  -0.903
341   Q        -1.054  -1.053  -1.041  -0.760  -0.758  -0.736  -0.928  -0.926  -0.903
342   L        -1.054  -1.053  -1.041  -1.380  -1.380  -1.358  -0.928  -0.926  -0.903
343   V        -1.054  -1.053  -1.041  -0.824  -0.820  -0.801  -0.928  -0.926  -0.903
344   E         0.142   0.170   0.117   0.180   0.228   0.132   0.021   0.065  -0.020
345   K         0.142   0.128   0.101  -0.073  -0.092  -0.133   0.021  -0.001  -0.045
346   K         0.142   0.170   0.117  -0.043   0.012  -0.096   0.021   0.065  -0.020
347   K         0.142   0.128   0.101  -0.057  -0.076  -0.114   0.021  -0.001  -0.045
348   I        -0.005  -0.004   0.011  -0.084  -0.083  -0.058  -0.217  -0.216  -0.191
349   T        -0.005  -0.004   0.011  -0.212  -0.211  -0.187  -0.217  -0.216  -0.191
350   K         1.790   1.791   1.809   1.547   1.551   1.577   1.918   1.920   1.943
351   N        -0.005  -0.004   0.011  -0.157  -0.157  -0.132  -0.217  -0.216  -0.191
352   P         1.790   1.791   1.809   1.932   1.934   1.963   1.918   1.920   1.943
353   P        -0.005  -0.004   0.011   0.058   0.059   0.084  -0.217  -0.216  -0.191
354   N        -0.005  -0.004   0.011   0.030   0.031   0.056  -0.217  -0.216  -0.191
355   S        -0.005  -0.004   0.011  -0.209  -0.209  -0.184  -0.217  -0.216  -0.191
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   H         1.790   1.791   1.809   2.048   2.050   2.080   1.918   1.920   1.943
358   H        -0.005  -0.004   0.011  -0.106  -0.105  -0.080  -0.217  -0.216  -0.191
359   P         1.790   1.791   1.809   1.932   1.934   1.963   1.918   1.920   1.943
360   H        -0.005  -0.004   0.011   0.142   0.142   0.168  -0.217  -0.216  -0.191
361   K        -0.005  -0.004   0.011  -0.187  -0.186  -0.162  -0.217  -0.216  -0.191
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   N         1.790   1.791   1.809   1.733   1.735   1.764   1.918   1.920   1.943
365   G         1.790   1.791   1.809   2.067   2.070   2.099   1.918   1.920   1.943
366   K        -0.005  -0.004   0.011  -0.113  -0.112  -0.088  -0.217  -0.216  -0.191
367   I        -0.005  -0.004   0.011  -0.277  -0.276  -0.252  -0.217  -0.216  -0.191
368   S         0.142   0.170   0.117   0.059   0.111   0.005   0.021   0.065  -0.020
369   F        -1.054  -1.053  -1.041  -1.137  -1.139  -1.114  -0.928  -0.926  -0.903
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q02209
Output conservation file - output/Q02209
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
