1     M         2.333   2.372   2.446   2.693   2.763   2.888   2.686   2.750   2.884
2     S        -0.829  -0.797  -0.811  -0.817  -0.791  -0.776  -0.757  -0.712  -0.714
3     S         0.822   0.844   0.872   0.505   0.538   0.572   0.561   0.593   0.620
4     L         0.822   0.844   0.872   0.563   0.594   0.636   0.561   0.593   0.620
5     L         0.822   0.844   0.872   0.445   0.475   0.504   0.561   0.593   0.620
6     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     L        -0.275  -0.261  -0.209  -0.477  -0.451  -0.377  -0.501  -0.479  -0.408
8     H        -0.275  -0.261  -0.209  -0.268  -0.249  -0.162  -0.501  -0.479  -0.408
9     C        -0.275  -0.261  -0.209  -0.112  -0.093  -0.001  -0.501  -0.479  -0.408
10    I        -0.275  -0.261  -0.209  -0.253  -0.228  -0.146  -0.501  -0.479  -0.408
11    R         2.333   2.372   2.446   2.477   2.543   2.666   2.686   2.750   2.884
12    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    L         0.822   0.793   0.838   0.523   0.465   0.537   0.561   0.493   0.552
14    P         0.998   1.070   1.001   1.068   1.179   1.082   0.893   1.017   0.871
15    Q        -0.135  -0.110  -0.107  -0.339  -0.302  -0.299  -0.302  -0.264  -0.261
16    R         2.333   2.372   2.446   2.465   2.532   2.653   2.686   2.750   2.884
17    S        -0.958  -0.944  -0.905  -0.738  -0.698  -0.646  -0.900  -0.877  -0.819
18    V         0.998   0.959   0.967   1.023   0.963   0.973   0.893   0.812   0.805
19    W        -0.135  -0.131  -0.113   0.012   0.002   0.047  -0.302  -0.296  -0.270
20    L        -0.829  -0.804  -0.818  -0.783  -0.739  -0.766  -0.757  -0.722  -0.723
21    S        -0.135  -0.178  -0.144  -0.133  -0.179  -0.116  -0.302  -0.362  -0.314
22    G         0.822   0.794   0.837   1.007   0.961   1.025   0.561   0.495   0.550
23    Y         0.822   0.794   0.837   0.961   0.906   0.972   0.561   0.495   0.550
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    K         0.998   1.077   0.976   0.883   1.010   0.820   0.893   1.029   0.824
27    Q        -0.958  -0.942  -0.905  -0.868  -0.843  -0.780  -0.900  -0.874  -0.819
28    K        -0.958  -0.942  -0.905  -1.050  -1.001  -0.968  -0.900  -0.874  -0.819
29    A        -0.958  -0.942  -0.905  -1.003  -0.977  -0.919  -0.900  -0.874  -0.819
30    R         0.998   0.932   0.935   1.097   0.991   0.987   0.893   0.761   0.743
31    C        -0.958  -0.942  -0.905  -0.687  -0.682  -0.594  -0.900  -0.874  -0.819
32    I        -0.958  -0.942  -0.905  -0.885  -0.848  -0.798  -0.900  -0.874  -0.819
33    H         0.998   1.055   0.971   1.357   1.456   1.317   0.893   0.990   0.813
34    S         0.077   0.084   0.007   0.063   0.073  -0.028   0.009   0.020  -0.092
35    S         0.077   0.055   0.002   0.030  -0.008  -0.078   0.009  -0.025  -0.101
36    A        -0.829  -0.871  -0.845  -0.821  -0.889  -0.859  -0.757  -0.798  -0.753
37    A         0.077   0.104   0.013   0.225   0.270   0.141   0.009   0.047  -0.084
38    N        -0.829  -0.869  -0.846  -0.707  -0.800  -0.745  -0.757  -0.796  -0.755
39    G        -1.487  -1.472  -1.444  -1.383  -1.378  -1.311  -1.139  -1.115  -1.066
40    D         0.077  -0.032  -0.036   0.216   0.048   0.032   0.009  -0.150  -0.156
41    F         1.145   1.108   1.054   1.294   1.237   1.145   1.156   1.085   0.972
42    M        -1.487  -1.472  -1.444  -1.029  -0.997  -0.946  -1.139  -1.115  -1.066
43    S         2.333   2.372   2.446   2.186   2.248   2.366   2.686   2.750   2.884
44    W         1.145   1.070   1.055   1.578   1.475   1.460   1.156   1.017   0.972
45    F         2.333   2.372   2.446   2.474   2.538   2.662   2.686   2.750   2.884
46    K        -0.829  -0.815  -0.814  -0.844  -0.812  -0.806  -0.757  -0.734  -0.718
47    R         0.077   0.055   0.002   0.250   0.235   0.129   0.009  -0.025  -0.101
48    K         0.077   0.058   0.007  -0.067  -0.106  -0.180   0.009  -0.021  -0.093
49    K         1.145   1.108   1.054   1.027   0.988   0.901   1.156   1.085   0.972
50    Q         0.077   0.087   0.007   0.202   0.208   0.101   0.009   0.024  -0.093
51    E        -0.829  -0.869  -0.846  -1.164  -1.247  -1.226  -0.757  -0.796  -0.755
52    E        -0.829  -0.719  -0.800  -0.948  -0.770  -0.900  -0.757  -0.617  -0.701
53    -         0.822   0.868   0.870   0.450   0.518   0.513   0.561   0.639   0.615
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    H        -0.135  -0.110  -0.107  -0.042  -0.012   0.014  -0.302  -0.264  -0.261
60    Q        -0.958  -0.944  -0.905  -0.823  -0.800  -0.734  -0.900  -0.877  -0.819
61    E        -0.135  -0.176  -0.142  -0.244  -0.300  -0.241  -0.302  -0.359  -0.312
62    P        -0.135  -0.124  -0.109  -0.110  -0.082  -0.080  -0.302  -0.286  -0.264
63    V        -0.829  -0.815  -0.814  -0.739  -0.721  -0.711  -0.757  -0.734  -0.718
64    K        -0.171  -0.116  -0.134  -0.355  -0.248  -0.271  -0.374  -0.298  -0.310
65    D        -0.829  -0.871  -0.845  -0.726  -0.808  -0.757  -0.757  -0.798  -0.753
66    T         0.077   0.055   0.002   0.281   0.250   0.168   0.009  -0.025  -0.101
67    K         0.736   0.743   0.792   0.363   0.374   0.444   0.391   0.392   0.459
68    Q        -0.171  -0.106  -0.131  -0.346  -0.233  -0.270  -0.374  -0.288  -0.308
69    L        -0.171  -0.203  -0.138  -0.367  -0.413  -0.309  -0.374  -0.405  -0.317
70    I        -0.829  -0.871  -0.845  -0.488  -0.542  -0.478  -0.757  -0.798  -0.753
71    K        -0.171  -0.127  -0.133  -0.510  -0.453  -0.445  -0.374  -0.317  -0.311
72    D        -1.487  -1.472  -1.444  -1.301  -1.262  -1.226  -1.139  -1.115  -1.066
73    I         0.077   0.055   0.002   0.217   0.184   0.101   0.009  -0.025  -0.101
74    E         1.145   1.070   1.055   1.056   0.946   0.926   1.156   1.017   0.972
75    E        -0.829  -0.802  -0.813  -0.873  -0.818  -0.859  -0.757  -0.720  -0.717
76    G         0.077  -0.032  -0.036   0.307   0.114   0.100   0.009  -0.150  -0.156
77    T         0.077   0.104   0.013  -0.070  -0.031  -0.175   0.009   0.047  -0.084
78    N        -1.487  -1.472  -1.444  -1.339  -1.329  -1.265  -1.139  -1.115  -1.066
79    E        -1.487  -1.472  -1.444  -1.358  -1.330  -1.285  -1.139  -1.115  -1.066
80    A        -1.487  -1.472  -1.444  -1.306  -1.262  -1.231  -1.139  -1.115  -1.066
81    S        -0.829  -0.784  -0.818  -0.844  -0.757  -0.813  -0.757  -0.697  -0.722
82    S        -0.829  -0.802  -0.813  -1.027  -0.968  -1.010  -0.757  -0.720  -0.717
83    Q        -0.171  -0.117  -0.134  -0.516  -0.448  -0.457  -0.374  -0.305  -0.313
84    S        -0.171  -0.201  -0.141  -0.383  -0.421  -0.330  -0.374  -0.403  -0.320
85    S        -0.829  -0.859  -0.833  -0.702  -0.746  -0.714  -0.757  -0.785  -0.740
86    S         0.077   0.087   0.007  -0.001   0.012  -0.109   0.009   0.024  -0.093
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    N        -0.958  -0.944  -0.905  -0.838  -0.813  -0.750  -0.900  -0.877  -0.819
90    K         0.998   0.967   0.971   0.740   0.688   0.674   0.893   0.827   0.813
91    N        -0.829  -0.804  -0.818  -0.594  -0.553  -0.567  -0.757  -0.722  -0.723
92    R        -0.171  -0.183  -0.143  -0.414  -0.442  -0.387  -0.374  -0.380  -0.322
93    L         0.077  -0.032  -0.036  -0.019  -0.185  -0.194   0.009  -0.150  -0.156
94    E         0.077  -0.032  -0.036  -0.035  -0.206  -0.222   0.009  -0.150  -0.156
95    L         0.077  -0.032  -0.036  -0.061  -0.240  -0.251   0.009  -0.150  -0.156
96    I        -0.829  -0.869  -0.846  -0.750  -0.831  -0.784  -0.757  -0.796  -0.755
97    P         0.077   0.058   0.007   0.284   0.243   0.161   0.009  -0.021  -0.093
98    E        -0.171  -0.185  -0.136  -0.426  -0.457  -0.386  -0.374  -0.383  -0.315
99    N        -0.829  -0.869  -0.846  -0.788  -0.893  -0.840  -0.757  -0.796  -0.755
100   F         1.145   1.070   1.055   1.421   1.331   1.327   1.156   1.017   0.972
101   I        -0.829  -0.869  -0.846  -0.653  -0.708  -0.671  -0.757  -0.796  -0.755
102   G         0.077  -0.032  -0.036   0.323   0.141   0.122   0.009  -0.150  -0.156
103   E        -0.171  -0.203  -0.138  -0.317  -0.359  -0.258  -0.374  -0.405  -0.317
104   G        -0.829  -0.802  -0.813  -0.571  -0.537  -0.535  -0.757  -0.720  -0.717
105   S        -0.829  -0.871  -0.845  -0.995  -1.051  -1.026  -0.757  -0.798  -0.753
106   R        -0.829  -0.784  -0.818  -0.953  -0.886  -0.933  -0.757  -0.697  -0.722
107   R        -0.829  -0.871  -0.845  -0.724  -0.790  -0.761  -0.757  -0.798  -0.753
108   C        -0.829  -0.802  -0.813  -0.575  -0.532  -0.515  -0.757  -0.720  -0.717
109   K         0.736   0.755   0.794   0.256   0.287   0.328   0.391   0.416   0.463
110   R        -0.958  -0.938  -0.905  -1.100  -1.056  -1.018  -0.900  -0.870  -0.819
111   Q         0.998   1.052   0.971   0.966   1.050   0.901   0.893   0.984   0.814
112   K        -0.275  -0.260  -0.209  -0.538  -0.508  -0.440  -0.501  -0.479  -0.408
113   E         0.822   0.834   0.837   0.588   0.602   0.603   0.561   0.573   0.550
114   L         0.822   0.832   0.838   0.433   0.437   0.411   0.561   0.569   0.552
115   K        -0.275  -0.260  -0.209  -0.682  -0.656  -0.589  -0.501  -0.479  -0.408
116   L         0.822   0.834   0.837   0.433   0.442   0.408   0.561   0.573   0.550
117   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   V        -0.135  -0.087  -0.109  -0.220  -0.143  -0.184  -0.302  -0.229  -0.264
119   S        -0.958  -0.942  -0.905  -1.076  -1.029  -0.994  -0.900  -0.874  -0.819
120   S        -0.958  -0.942  -0.905  -0.920  -0.875  -0.834  -0.900  -0.874  -0.819
121   A        -0.958  -0.942  -0.905  -0.766  -0.717  -0.675  -0.900  -0.874  -0.819
122   P         0.998   1.044   0.967   1.115   1.194   1.044   0.893   0.970   0.805
123   F        -0.135  -0.163  -0.142  -0.039  -0.097  -0.062  -0.302  -0.341  -0.312
124   N         0.998   0.932   0.935   1.121   1.003   0.987   0.893   0.761   0.743
125   Q        -0.135  -0.087  -0.109  -0.354  -0.268  -0.339  -0.302  -0.229  -0.264
126   W         0.998   0.932   0.935   1.272   1.151   1.138   0.893   0.761   0.743
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   L         1.145   1.070   1.055   1.050   0.942   0.923   1.156   1.017   0.972
129   S         1.145   1.070   1.055   1.054   0.946   0.922   1.156   1.017   0.972
130   R        -0.829  -0.797  -0.811  -0.724  -0.677  -0.698  -0.757  -0.712  -0.714
131   D         0.077  -0.032  -0.036   0.196   0.018   0.005   0.009  -0.150  -0.156
132   K         2.333   2.372   2.446   2.142   2.213   2.321   2.686   2.750   2.884
133   I        -0.829  -0.804  -0.818  -0.876  -0.840  -0.849  -0.757  -0.722  -0.723
134   T        -1.487  -1.472  -1.444  -1.478  -1.433  -1.408  -1.139  -1.115  -1.066
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   S         0.077   0.087   0.007   0.097   0.119   0.014   0.009   0.024  -0.093
140   D        -1.487  -1.472  -1.444  -1.537  -1.490  -1.469  -1.139  -1.115  -1.066
141   N        -0.829  -0.784  -0.818  -0.806  -0.747  -0.773  -0.757  -0.697  -0.722
142   Q         0.077   0.055   0.002   0.052   0.001  -0.099   0.009  -0.025  -0.101
143   L         2.333   2.372   2.446   2.170   2.229   2.349   2.686   2.750   2.884
144   D        -1.487  -1.472  -1.444  -1.466  -1.455  -1.396  -1.139  -1.115  -1.066
145   D        -0.829  -0.804  -0.818  -0.649  -0.615  -0.619  -0.757  -0.722  -0.723
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   M        -0.171  -0.117  -0.131  -0.122  -0.059  -0.039  -0.374  -0.305  -0.309
149   I         0.077   0.087   0.007   0.132   0.143   0.003   0.009   0.024  -0.093
150   L        -0.829  -0.871  -0.845  -0.794  -0.842  -0.791  -0.757  -0.798  -0.753
151   Q         0.077   0.074   0.013  -0.072  -0.094  -0.188   0.009   0.001  -0.084
152   A         0.077   0.058   0.007   0.147   0.121   0.030   0.009  -0.021  -0.093
153   T        -0.829  -0.786  -0.812  -0.575  -0.496  -0.552  -0.757  -0.699  -0.716
154   E        -0.829  -0.786  -0.812  -1.000  -0.924  -0.997  -0.757  -0.699  -0.716
155   K         0.077   0.199   0.043  -0.038   0.149  -0.097   0.009   0.190  -0.039
156   T        -0.171  -0.201  -0.141  -0.195  -0.241  -0.143  -0.374  -0.403  -0.320
157   L        -0.135  -0.124  -0.109  -0.267  -0.258  -0.219  -0.302  -0.286  -0.264
158   G         1.145   1.108   1.054   1.380   1.327   1.228   1.156   1.085   0.972
159   K        -0.829  -0.784  -0.818  -0.748  -0.656  -0.732  -0.757  -0.697  -0.722
160   V         0.077   0.055   0.002   0.120   0.071  -0.009   0.009  -0.025  -0.101
161   D        -0.829  -0.802  -0.813  -0.885  -0.868  -0.855  -0.757  -0.720  -0.717
162   Q        -0.829  -0.802  -0.813  -0.666  -0.629  -0.631  -0.757  -0.720  -0.717
163   D        -0.829  -0.859  -0.833  -0.948  -1.012  -0.953  -0.757  -0.785  -0.740
164   -        -0.275  -0.261  -0.209  -0.483  -0.449  -0.384  -0.501  -0.479  -0.408
165   -        -0.275  -0.261  -0.209  -0.307  -0.276  -0.202  -0.501  -0.479  -0.408
166   -        -0.275  -0.261  -0.209  -0.517  -0.497  -0.419  -0.501  -0.479  -0.408
167   -         0.822   0.825   0.865   0.817   0.813   0.866   0.561   0.555   0.606
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   V        -0.829  -0.802  -0.813  -0.657  -0.601  -0.640  -0.757  -0.720  -0.717
171   Q        -0.829  -0.802  -0.813  -0.748  -0.730  -0.721  -0.757  -0.720  -0.717
172   F         0.736   0.721   0.776   0.540   0.474   0.556   0.391   0.348   0.427
173   S        -1.487  -1.472  -1.444  -1.395  -1.346  -1.322  -1.139  -1.115  -1.066
174   D         0.077   0.087   0.007   0.278   0.297   0.182   0.009   0.024  -0.093
175   L         1.145   1.225   1.085   1.050   1.163   0.971   1.156   1.290   1.030
176   V        -0.171  -0.118  -0.133  -0.392  -0.329  -0.337  -0.374  -0.300  -0.310
177   A        -1.487  -1.472  -1.444  -1.432  -1.408  -1.361  -1.139  -1.115  -1.066
178   K         0.736   0.803   0.827   0.506   0.650   0.653   0.391   0.512   0.529
179   F         1.145   1.108   1.054   1.294   1.237   1.145   1.156   1.085   0.972
180   Q        -0.829  -0.786  -0.812  -1.010  -0.952  -0.986  -0.757  -0.699  -0.716
181   F         1.145   1.108   1.054   1.294   1.237   1.145   1.156   1.085   0.972
182   T        -0.829  -0.786  -0.812  -0.860  -0.802  -0.825  -0.757  -0.699  -0.716
183   K         2.333   2.372   2.446   2.142   2.213   2.321   2.686   2.750   2.884
184   F        -0.829  -0.786  -0.812  -0.938  -0.880  -0.910  -0.757  -0.699  -0.716
185   L         1.145   1.108   1.054   1.069   1.019   0.950   1.156   1.085   0.972
186   Q         2.333   2.372   2.446   2.364   2.423   2.549   2.686   2.750   2.884
187   S        -1.487  -1.472  -1.444  -1.325  -1.315  -1.251  -1.139  -1.115  -1.066
188   K         0.077  -0.032  -0.036  -0.067  -0.232  -0.248   0.009  -0.150  -0.156
189   S         0.077   0.055   0.002  -0.033  -0.083  -0.158   0.009  -0.025  -0.101
190   G         2.333   2.372   2.446   2.567   2.633   2.758   2.686   2.750   2.884
191   Y        -0.829  -0.869  -0.846  -0.359  -0.430  -0.368  -0.757  -0.796  -0.755
192   L        -0.829  -0.859  -0.833  -0.737  -0.772  -0.746  -0.757  -0.785  -0.740
193   I         2.333   2.372   2.446   2.401   2.465   2.587   2.686   2.750   2.884
194   P         1.145   1.070   1.055   1.415   1.312   1.296   1.156   1.017   0.972
195   D         2.333   2.372   2.446   2.416   2.484   2.603   2.686   2.750   2.884
196   Y         1.145   1.108   1.054   1.431   1.378   1.283   1.156   1.085   0.972
197   E         0.077  -0.032  -0.036   0.009  -0.161  -0.163   0.009  -0.150  -0.156
198   L         1.145   1.108   1.054   1.050   0.998   0.923   1.156   1.085   0.972
199   T         1.145   1.108   1.054   1.277   1.227   1.129   1.156   1.085   0.972
200   T        -0.829  -0.815  -0.814  -0.711  -0.700  -0.689  -0.757  -0.734  -0.718
201   L         0.077  -0.032  -0.036  -0.077  -0.263  -0.273   0.009  -0.150  -0.156
202   S        -1.487  -1.472  -1.444  -1.361  -1.286  -1.288  -1.139  -1.115  -1.066
203   T         1.145   1.225   1.085   1.277   1.407   1.184   1.156   1.290   1.030
204   P         1.145   1.070   1.055   1.345   1.229   1.197   1.156   1.017   0.972
205   L        -0.829  -0.871  -0.845  -0.964  -1.018  -0.987  -0.757  -0.798  -0.753
206   Q        -1.487  -1.472  -1.444  -1.293  -1.254  -1.217  -1.139  -1.115  -1.066
207   F        -0.829  -0.871  -0.845  -0.724  -0.819  -0.765  -0.757  -0.798  -0.753
208   K        -0.829  -0.871  -0.845  -0.821  -0.852  -0.817  -0.757  -0.798  -0.753
209   R        -0.171  -0.202  -0.143  -0.283  -0.327  -0.235  -0.374  -0.403  -0.323
210   Y         0.077   0.058   0.007   0.451   0.404   0.348   0.009  -0.021  -0.093
211   I        -0.171  -0.106  -0.131  -0.302  -0.233  -0.243  -0.374  -0.288  -0.308
212   K        -0.829  -0.804  -0.818  -0.810  -0.736  -0.778  -0.757  -0.722  -0.723
213   E        -0.829  -0.784  -0.818  -0.853  -0.774  -0.850  -0.757  -0.697  -0.722
214   K        -0.829  -0.871  -0.845  -0.971  -1.040  -0.990  -0.757  -0.798  -0.753
215   I         0.077   0.087   0.007   0.141   0.148   0.014   0.009   0.024  -0.093
216   L        -0.829  -0.871  -0.845  -0.899  -0.970  -0.911  -0.757  -0.798  -0.753
217   P         0.077   0.074   0.013   0.083   0.078   0.006   0.009   0.001  -0.084
218   S        -0.829  -0.859  -0.833  -0.575  -0.618  -0.586  -0.757  -0.785  -0.740
219   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   K         0.822   0.834   0.837   0.454   0.471   0.469   0.561   0.573   0.550
224   L         2.333   2.372   2.446   2.214   2.275   2.395   2.686   2.750   2.884
225   A         0.822   0.834   0.837   0.872   0.894   0.898   0.561   0.573   0.550
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   Y        -0.171  -0.202  -0.143   0.021  -0.019   0.076  -0.374  -0.403  -0.323
228   K         0.736   0.721   0.776   0.422   0.406   0.495   0.391   0.348   0.427
229   E         0.077   0.084   0.007   0.026   0.049  -0.073   0.009   0.020  -0.092
230   A        -0.829  -0.859  -0.833  -0.713  -0.730  -0.688  -0.757  -0.785  -0.740
231   E         1.145   1.070   1.055   1.082   0.975   0.962   1.156   1.017   0.972
232   P         2.333   2.372   2.446   2.526   2.593   2.716   2.686   2.750   2.884
233   N         1.145   1.225   1.085   1.343   1.454   1.269   1.156   1.290   1.030
234   A         2.333   2.372   2.446   2.369   2.428   2.554   2.686   2.750   2.884
235   I         2.333   2.372   2.446   2.401   2.465   2.587   2.686   2.750   2.884
236   H        -0.829  -0.869  -0.846  -0.365  -0.431  -0.390  -0.757  -0.796  -0.755
237   P         1.145   1.249   1.087   1.082   1.226   1.017   1.156   1.331   1.032
238   F        -1.487  -1.472  -1.444  -1.252  -1.213  -1.176  -1.139  -1.115  -1.066
239   S        -1.487  -1.472  -1.444  -1.328  -1.296  -1.254  -1.139  -1.115  -1.066
240   D        -0.829  -0.869  -0.846  -0.853  -0.946  -0.907  -0.757  -0.796  -0.755
241   N        -0.829  -0.719  -0.800  -0.715  -0.527  -0.666  -0.757  -0.617  -0.701
242   Y         0.736   0.802   0.829   0.788   0.895   0.941   0.391   0.509   0.533
243   A        -0.958  -0.944  -0.905  -1.122  -1.093  -1.041  -0.900  -0.877  -0.819
244   S        -0.829  -0.784  -0.818  -0.664  -0.584  -0.635  -0.757  -0.697  -0.722
245   P         1.145   1.108   1.054   1.349   1.297   1.202   1.156   1.085   0.972
246   N         2.333   2.372   2.446   2.463   2.518   2.651   2.686   2.750   2.884
247   I         1.145   1.249   1.087   1.231   1.382   1.156   1.156   1.331   1.032
248   Y         0.077   0.084   0.007   0.455   0.474   0.356   0.009   0.020  -0.092
249   V         1.145   1.070   1.055   1.174   1.054   1.024   1.156   1.017   0.972
250   V         1.145   1.070   1.055   1.246   1.140   1.127   1.156   1.017   0.972
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   N        -0.829  -0.869  -0.846  -0.668  -0.766  -0.699  -0.757  -0.796  -0.755
253   D        -0.829  -0.871  -0.845  -0.851  -0.935  -0.902  -0.757  -0.798  -0.753
254   V         0.077  -0.032  -0.036   0.098  -0.093  -0.103   0.009  -0.150  -0.156
255   T        -1.487  -1.472  -1.444  -1.516  -1.515  -1.448  -1.139  -1.115  -1.066
256   S        -1.487  -1.472  -1.444  -1.417  -1.395  -1.346  -1.139  -1.115  -1.066
257   K        -0.829  -0.815  -0.814  -1.051  -1.034  -1.033  -0.757  -0.734  -0.718
258   E         0.077   0.087   0.007  -0.003   0.008  -0.111   0.009   0.024  -0.093
259   Q        -0.171  -0.128  -0.130  -0.271  -0.201  -0.212  -0.374  -0.318  -0.308
260   K         0.077  -0.032  -0.036  -0.101  -0.276  -0.294   0.009  -0.150  -0.156
261   S         0.077   0.074   0.013   0.115   0.106   0.002   0.009   0.001  -0.084
262   K         0.077  -0.032  -0.036  -0.044  -0.205  -0.217   0.009  -0.150  -0.156
263   Y        -0.829  -0.797  -0.811  -0.492  -0.415  -0.457  -0.757  -0.712  -0.714
264   D        -0.171  -0.203  -0.138  -0.340  -0.363  -0.271  -0.374  -0.405  -0.317
265   T        -0.829  -0.869  -0.846  -0.814  -0.885  -0.869  -0.757  -0.796  -0.755
266   I         0.736   0.803   0.827   0.408   0.513   0.547   0.391   0.512   0.529
267   M         0.077   0.104   0.013   0.092   0.116   0.020   0.009   0.047  -0.084
268   K        -0.171  -0.183  -0.140  -0.617  -0.630  -0.575  -0.374  -0.381  -0.319
269   E         0.077   0.055   0.002  -0.042  -0.091  -0.169   0.009  -0.025  -0.101
270   I        -0.171  -0.106  -0.131  -0.249  -0.157  -0.178  -0.374  -0.288  -0.308
271   Q        -1.487  -1.472  -1.444  -1.499  -1.506  -1.430  -1.139  -1.115  -1.066
272   K        -0.958  -0.942  -0.905  -1.084  -1.051  -1.002  -0.900  -0.874  -0.819
273   L         0.998   0.932   0.935   0.892   0.795   0.799   0.893   0.761   0.743
274   E         0.998   0.932   0.935   0.828   0.712   0.713   0.893   0.761   0.743
275   D        -0.135  -0.065  -0.109  -0.314  -0.212  -0.274  -0.302  -0.197  -0.263
276   D        -0.135  -0.072  -0.113  -0.209  -0.104  -0.185  -0.302  -0.208  -0.270
277   A        -0.958  -0.942  -0.905  -0.632  -0.588  -0.537  -0.900  -0.874  -0.819
278   T        -0.135  -0.156  -0.144  -0.159  -0.191  -0.194  -0.302  -0.332  -0.314
279   R         0.998   0.932   0.935   1.003   0.879   0.857   0.893   0.761   0.743
280   K        -0.958  -0.942  -0.905  -1.133  -1.110  -1.053  -0.900  -0.874  -0.819
281   A        -0.135  -0.163  -0.142  -0.178  -0.235  -0.195  -0.302  -0.341  -0.312
282   L        -0.135  -0.156  -0.144  -0.228  -0.249  -0.228  -0.302  -0.332  -0.314
283   E         0.998   0.932   0.935   0.748   0.618   0.602   0.893   0.761   0.743
284   T        -0.171  -0.117  -0.134  -0.514  -0.440  -0.451  -0.374  -0.305  -0.313
285   A         2.333   2.372   2.446   2.369   2.428   2.554   2.686   2.750   2.884
286   R        -0.135  -0.168  -0.144  -0.294  -0.369  -0.354  -0.302  -0.350  -0.314
287   S        -0.829  -0.719  -0.800  -0.903  -0.741  -0.854  -0.757  -0.617  -0.701
288   A        -1.487  -1.472  -1.444  -1.440  -1.419  -1.369  -1.139  -1.115  -1.066
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q02204
Output conservation file - output/Q02204
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
