1     M         1.054   1.070   1.141   1.263   1.288   1.379   1.130   1.153   1.257
2     S         0.399   0.249   0.133   0.499   0.298   0.095   0.389   0.150  -0.082
3     -        -1.261  -1.252  -1.108  -1.372  -1.368  -1.169  -1.308  -1.293  -1.086
4     -        -1.261  -1.252  -1.108  -1.279  -1.257  -1.049  -1.308  -1.293  -1.086
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -0.811  -0.867  -1.038  -0.804  -0.904  -1.218  -0.775  -0.849  -1.010
7     P         0.399   0.358   0.144   0.562   0.507   0.176   0.389   0.325  -0.062
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    G        -0.095  -0.118   0.008  -0.170  -0.203  -0.001  -0.458  -0.509  -0.316
14    R        -0.095  -0.118   0.008  -0.264  -0.335  -0.144  -0.458  -0.509  -0.316
15    T         0.077  -0.022   0.029   0.036  -0.165  -0.128  -0.140  -0.326  -0.276
16    I         0.399   0.358   0.144   0.425   0.369   0.024   0.389   0.325  -0.062
17    L         0.399   0.358   0.144   0.293   0.249  -0.042   0.389   0.325  -0.062
18    A         0.399   0.249   0.133   0.468   0.262   0.075   0.389   0.150  -0.082
19    S         0.399   0.249   0.133   0.501   0.301   0.100   0.389   0.150  -0.082
20    K        -0.811  -0.734  -1.019  -0.583  -0.477  -0.925  -0.775  -0.680  -0.989
21    V         0.077   0.098   0.048  -0.065  -0.035  -0.166  -0.140  -0.108  -0.239
22    A         0.077   0.157   0.084   0.001   0.124  -0.013  -0.140  -0.005  -0.172
23    E         0.077   0.098   0.048  -0.073  -0.038  -0.147  -0.140  -0.108  -0.239
24    T        -1.054  -1.103  -1.080  -0.973  -1.057  -1.040  -1.092  -1.134  -1.058
25    F        -0.510  -0.576  -0.582  -0.425  -0.526  -0.594  -0.669  -0.737  -0.743
26    N        -1.843  -1.791  -1.748  -1.809  -1.775  -1.671  -1.516  -1.465  -1.337
27    T        -1.843  -1.796  -1.757  -1.611  -1.561  -1.486  -1.516  -1.470  -1.344
28    E        -0.224  -0.216  -0.523  -0.042  -0.031  -0.428  -0.246  -0.235  -0.660
29    I        -0.639  -0.667  -0.610  -0.923  -0.977  -0.883  -0.881  -0.907  -0.788
30    I        -1.843  -1.854  -1.762  -1.680  -1.707  -1.622  -1.516  -1.520  -1.347
31    N        -1.656  -1.615  -1.469  -1.691  -1.614  -1.396  -1.516  -1.466  -1.245
32    N        -2.258  -2.231  -2.037  -2.035  -1.971  -1.694  -1.727  -1.694  -1.439
33    V        -0.510  -0.521  -0.593  -0.726  -0.789  -0.886  -0.669  -0.708  -0.763
34    E        -1.656  -1.662  -1.475  -1.770  -1.769  -1.475  -1.516  -1.502  -1.249
35    E        -1.542  -1.583  -1.461  -1.517  -1.600  -1.426  -1.410  -1.433  -1.237
36    Y        -0.811  -0.915  -1.048  -0.817  -0.973  -1.117  -0.775  -0.907  -1.021
37    K        -1.542  -1.398  -1.442  -1.543  -1.312  -1.372  -1.410  -1.255  -1.220
38    K        -1.843  -1.792  -1.761  -1.587  -1.519  -1.529  -1.516  -1.466  -1.346
39    T        -1.957  -1.953  -1.771  -1.909  -1.898  -1.632  -1.621  -1.602  -1.354
40    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
47    L        -1.127  -1.172  -1.092  -1.359  -1.391  -1.210  -1.198  -1.227  -1.071
48    L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
49    V         0.399   0.249   0.133   0.364   0.158  -0.024   0.389   0.150  -0.082
50    G         0.399   0.249   0.133   0.500   0.295   0.093   0.389   0.150  -0.082
51    F         0.399   0.476   0.157   0.574   0.675   0.161   0.389   0.502  -0.038
52    L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
53    A         0.077   0.093   0.054   0.001   0.021  -0.068  -0.140  -0.116  -0.228
54    N         0.399   0.249   0.133   0.455   0.260   0.075   0.389   0.150  -0.082
55    N        -1.127  -1.094  -1.074  -1.210  -1.148  -1.094  -1.198  -1.151  -1.054
56    D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
57    P         0.399   0.464   0.158   0.562   0.641   0.200   0.389   0.485  -0.037
58    A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
59    A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
60    K        -1.542  -1.600  -1.460  -1.577  -1.675  -1.431  -1.410  -1.446  -1.237
61    M         0.399   0.249   0.133   0.700   0.508   0.301   0.389   0.150  -0.082
62    Y         1.054   1.070   1.141   1.138   1.164   1.265   1.130   1.153   1.257
63    A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
64    T        -1.957  -1.910  -1.775  -1.915  -1.849  -1.641  -1.621  -1.573  -1.357
65    W         1.054   1.070   1.141   1.333   1.352   1.444   1.130   1.153   1.257
66    T         0.399   0.249   0.133   0.547   0.342   0.143   0.389   0.150  -0.082
67    Q        -1.127  -1.216  -1.096  -1.110  -1.237  -1.075  -1.198  -1.266  -1.075
68    K         0.077   0.022   0.037  -0.039  -0.127  -0.113  -0.140  -0.244  -0.261
69    T         1.054   1.070   1.141   1.125   1.144   1.253   1.130   1.153   1.257
70    S        -0.095  -0.034   0.032  -0.103   0.013   0.069  -0.458  -0.349  -0.271
71    E         0.399   0.358   0.144   0.482   0.432   0.117   0.389   0.325  -0.062
72    S        -1.054  -1.051  -1.077  -1.031  -1.062  -1.077  -1.092  -1.107  -1.057
73    M        -1.054  -1.138  -1.075  -1.148  -1.267  -1.145  -1.092  -1.166  -1.052
74    G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
75    F         0.399   0.464   0.158   0.586   0.670   0.190   0.389   0.485  -0.037
76    R        -1.542  -1.524  -1.462  -1.442  -1.429  -1.345  -1.410  -1.389  -1.239
77    Y         0.399   0.249   0.133   0.575   0.384   0.192   0.389   0.150  -0.082
78    D        -0.095  -0.098   0.011  -0.308  -0.322  -0.153  -0.458  -0.471  -0.310
79    L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
80    R        -0.224  -0.135  -0.524  -0.036   0.087  -0.555  -0.246  -0.123  -0.661
81    V        -1.656  -1.665  -1.475  -1.694  -1.712  -1.410  -1.516  -1.504  -1.250
82    I        -0.639  -0.564  -0.598  -0.939  -0.814  -0.864  -0.881  -0.769  -0.768
83    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    D        -0.224  -0.205  -0.523  -0.079  -0.051  -0.526  -0.246  -0.222  -0.660
85    K         0.399   0.474   0.157   0.412   0.508   0.086   0.389   0.500  -0.038
86    D        -0.753  -0.752  -0.639  -0.922  -0.929  -0.767  -0.987  -0.987  -0.821
87    F        -0.639  -0.703  -0.611  -0.705  -0.781  -0.646  -0.881  -0.930  -0.785
88    L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
89    E         1.054   1.070   1.141   1.053   1.075   1.187   1.130   1.153   1.257
90    E        -0.811  -0.776  -1.035  -0.642  -0.596  -0.985  -0.775  -0.730  -1.007
91    A        -0.224  -0.342  -0.541  -0.100  -0.273  -0.575  -0.246  -0.416  -0.686
92    I         0.077   0.139   0.078  -0.092   0.013  -0.143  -0.140  -0.035  -0.184
93    I        -0.510  -0.493  -0.587  -0.573  -0.559  -0.673  -0.669  -0.649  -0.753
94    Q        -1.957  -1.961  -1.781  -1.844  -1.860  -1.587  -1.621  -1.608  -1.361
95    A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
96    N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
97    G        -1.542  -1.390  -1.449  -1.519  -1.292  -1.337  -1.410  -1.252  -1.227
98    D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
99    D        -0.224  -0.216  -0.523  -0.074  -0.061  -0.515  -0.246  -0.235  -0.660
100   S        -1.054  -1.105  -1.072  -1.065  -1.142  -1.115  -1.092  -1.138  -1.050
101   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
102   N        -0.150  -0.127   0.007  -0.438  -0.395  -0.177  -0.563  -0.527  -0.317
103   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
104   I         0.399   0.441   0.151   0.471   0.523   0.153   0.389   0.451  -0.050
105   M         0.399   0.249   0.133   0.655   0.439   0.183   0.389   0.150  -0.082
106   V        -0.095  -0.064   0.021  -0.427  -0.377  -0.239  -0.458  -0.406  -0.291
107   Y         1.054   1.070   1.141   1.138   1.164   1.265   1.130   1.153   1.257
108   F         0.399   0.249   0.133   0.612   0.413   0.213   0.389   0.150  -0.082
109   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
110   V         0.399   0.249   0.133   0.361   0.153  -0.033   0.389   0.150  -0.082
111   F         0.399   0.249   0.133   0.640   0.455   0.286   0.389   0.150  -0.082
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   G         0.077  -0.022   0.029   0.019  -0.164  -0.118  -0.140  -0.326  -0.276
115   N        -1.127  -1.172  -1.092  -1.142  -1.167  -1.011  -1.198  -1.227  -1.071
116   A        -1.241  -1.289  -1.112  -1.385  -1.443  -1.171  -1.304  -1.334  -1.091
117   Q         1.054   1.070   1.141   1.191   1.218   1.314   1.130   1.153   1.257
118   D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
119   Q        -0.224  -0.336  -0.545   0.028  -0.137  -0.503  -0.246  -0.407  -0.690
120   Y         1.054   1.070   1.141   1.138   1.164   1.265   1.130   1.153   1.257
121   L         0.077   0.013   0.036  -0.197  -0.310  -0.279  -0.140  -0.262  -0.262
122   Q         0.399   0.249   0.133   0.600   0.394   0.163   0.389   0.150  -0.082
123   Q         0.399   0.249   0.133   0.610   0.409   0.190   0.389   0.150  -0.082
124   V        -0.639  -0.715  -0.614  -0.985  -1.065  -0.884  -0.881  -0.950  -0.791
125   V        -0.510  -0.432  -0.576  -0.616  -0.498  -0.669  -0.669  -0.555  -0.736
126   C        -0.510  -0.494  -0.590  -0.477  -0.491  -0.585  -0.669  -0.672  -0.759
127   K        -1.542  -1.536  -1.458  -1.502  -1.517  -1.388  -1.410  -1.390  -1.234
128   E        -0.510  -0.638  -0.607  -0.533  -0.720  -0.692  -0.669  -0.830  -0.780
129   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
130   D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
131   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
132   E         1.054   1.070   1.141   1.053   1.075   1.187   1.130   1.153   1.257
133   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
134   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
135   N        -0.510  -0.563  -0.608  -0.477  -0.559  -0.594  -0.669  -0.768  -0.782
136   H         0.077   0.139   0.078   0.252   0.347   0.207  -0.140  -0.035  -0.184
137   V        -1.843  -1.876  -1.774  -1.814  -1.861  -1.710  -1.516  -1.536  -1.356
138   Y        -0.224  -0.336  -0.545   0.040  -0.101  -0.398  -0.246  -0.407  -0.690
139   Y        -0.811  -0.950  -1.059  -0.644  -0.881  -1.134  -0.775  -0.945  -1.034
140   Q        -1.542  -1.601  -1.474  -1.232  -1.299  -1.140  -1.410  -1.448  -1.248
141   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
142   L        -0.095  -0.114   0.008  -0.368  -0.376  -0.158  -0.458  -0.501  -0.316
143   Y         1.054   1.070   1.141   1.138   1.164   1.265   1.130   1.153   1.257
144   H         1.054   1.070   1.141   1.274   1.293   1.389   1.130   1.153   1.257
145   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
146   V         0.077   0.092   0.050  -0.114  -0.094  -0.186  -0.140  -0.118  -0.236
147   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
148   Y        -0.510  -0.476  -0.568  -0.350  -0.277  -0.426  -0.669  -0.603  -0.725
149   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
150   D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
151   K        -1.542  -1.400  -1.444  -1.479  -1.265  -1.351  -1.410  -1.265  -1.223
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   E        -1.542  -1.541  -1.451  -1.413  -1.408  -1.267  -1.410  -1.395  -1.229
154   N        -1.054  -0.981  -1.061  -1.084  -0.980  -1.077  -1.092  -1.008  -1.040
155   R        -1.656  -1.664  -1.471  -1.581  -1.624  -1.332  -1.516  -1.504  -1.246
156   L        -0.826  -0.829  -0.655  -1.127  -1.129  -0.852  -1.092  -1.090  -0.841
157   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
158   S         0.399   0.434   0.152   0.532   0.579   0.211   0.389   0.440  -0.046
159   I         1.054   1.070   1.141   1.022   1.042   1.158   1.130   1.153   1.257
160   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
161   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
162   C         1.054   1.070   1.141   1.280   1.299   1.394   1.130   1.153   1.257
163   T         1.054   1.070   1.141   1.125   1.144   1.253   1.130   1.153   1.257
164   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
165   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
166   A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
167   I        -0.510  -0.404  -0.567  -0.512  -0.360  -0.603  -0.669  -0.521  -0.723
168   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
169   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
170   I         0.399   0.249   0.133   0.451   0.250   0.072   0.389   0.150  -0.082
171   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
172   E         1.054   1.070   1.141   1.053   1.075   1.187   1.130   1.153   1.257
173   F        -0.224  -0.119  -0.516   0.040   0.176  -0.355  -0.246  -0.102  -0.650
174   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
175   K        -0.639  -0.703  -0.611  -0.783  -0.827  -0.682  -0.881  -0.930  -0.785
176   I        -0.510  -0.504  -0.590  -0.632  -0.651  -0.730  -0.669  -0.679  -0.759
177   Y         1.054   1.070   1.141   1.138   1.164   1.265   1.130   1.153   1.257
178   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
179   N        -1.957  -1.923  -1.772  -1.932  -1.876  -1.636  -1.621  -1.581  -1.355
180   L        -1.054  -0.927  -1.059  -1.171  -0.957  -1.172  -1.092  -0.931  -1.035
181   L         0.399   0.358   0.144   0.276   0.227  -0.087   0.389   0.325  -0.062
182   P        -1.054  -1.156  -1.088  -0.891  -1.049  -0.964  -1.092  -1.188  -1.065
183   E        -0.095  -0.023   0.041  -0.240  -0.100  -0.035  -0.458  -0.327  -0.254
184   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
185   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
186   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
187   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
188   Y         0.399   0.249   0.133   0.575   0.384   0.192   0.389   0.150  -0.082
189   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
190   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
191   K        -0.150  -0.118   0.012  -0.429  -0.361  -0.152  -0.563  -0.508  -0.308
192   C        -0.826  -0.767  -0.642  -0.973  -0.897  -0.720  -1.092  -1.009  -0.824
193   I        -1.542  -1.399  -1.449  -1.530  -1.289  -1.393  -1.410  -1.258  -1.227
194   V        -0.095  -0.072   0.019  -0.427  -0.392  -0.243  -0.458  -0.421  -0.295
195   I         0.077   0.031   0.037  -0.114  -0.200  -0.210  -0.140  -0.227  -0.261
196   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
197   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
198   S         1.054   1.070   1.141   1.080   1.105   1.212   1.130   1.153   1.257
199   E         1.054   1.070   1.141   1.053   1.075   1.187   1.130   1.153   1.257
200   I         0.399   0.249   0.133   0.425   0.211   0.004   0.389   0.150  -0.082
201   V         0.399   0.249   0.133   0.361   0.156  -0.031   0.389   0.150  -0.082
202   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
203   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
204   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
205   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
206   A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
207   A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
208   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
209   L         0.399   0.464   0.158   0.312   0.396   0.027   0.389   0.485  -0.037
210   A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
211   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
212   D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
213   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
214   A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
215   T        -0.811  -0.771  -1.027  -0.612  -0.562  -0.991  -0.775  -0.724  -0.998
216   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
217   Y         0.399   0.474   0.157   0.575   0.672   0.233   0.389   0.500  -0.038
218   S         1.054   1.070   1.141   1.080   1.105   1.212   1.130   1.153   1.257
219   V         0.399   0.441   0.151   0.399   0.450   0.095   0.389   0.451  -0.050
220   D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
221   V         0.399   0.486   0.157   0.425   0.535   0.049   0.389   0.516  -0.038
222   N        -0.510  -0.602  -0.608  -0.500  -0.634  -0.606  -0.669  -0.800  -0.782
223   N         0.077   0.013   0.036  -0.017  -0.127  -0.117  -0.140  -0.262  -0.262
224   I         0.077  -0.022   0.029  -0.065  -0.261  -0.208  -0.140  -0.326  -0.276
225   Q         1.054   1.070   1.141   1.191   1.218   1.314   1.130   1.153   1.257
226   K        -1.054  -1.156  -1.088  -1.035  -1.176  -1.046  -1.092  -1.188  -1.065
227   F         0.399   0.434   0.152   0.612   0.657   0.247   0.389   0.440  -0.046
228   T         0.399   0.434   0.152   0.547   0.590   0.177   0.389   0.440  -0.046
229   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
230   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
231   E        -1.054  -1.003  -1.063  -1.024  -0.946  -1.020  -1.092  -1.022  -1.040
232   S        -0.753  -0.654  -0.610  -0.879  -0.711  -0.671  -0.987  -0.846  -0.781
233   L         0.077  -0.022   0.029  -0.197  -0.371  -0.291  -0.140  -0.326  -0.276
234   K        -1.241  -1.217  -1.110  -1.402  -1.344  -1.195  -1.304  -1.274  -1.090
235   L        -1.656  -1.689  -1.479  -1.696  -1.706  -1.406  -1.516  -1.521  -1.253
236   N        -1.843  -1.772  -1.753  -1.785  -1.721  -1.664  -1.516  -1.449  -1.340
237   K        -0.150  -0.126   0.009  -0.406  -0.357  -0.141  -0.563  -0.524  -0.315
238   H         1.054   1.070   1.141   1.274   1.293   1.389   1.130   1.153   1.257
239   H        -1.542  -1.601  -1.474  -1.354  -1.431  -1.286  -1.410  -1.448  -1.248
240   V         0.399   0.434   0.152   0.364   0.408   0.010   0.389   0.440  -0.046
241   E        -1.355  -1.430  -1.450  -1.225  -1.326  -1.419  -1.198  -1.276  -1.227
242   D         0.399   0.434   0.152   0.505   0.552   0.167   0.389   0.440  -0.046
243   L        -0.330  -0.468  -0.582  -0.489  -0.707  -0.901  -0.391  -0.591  -0.742
244   G        -0.597  -0.620  -0.633  -0.610  -0.651  -0.706  -0.767  -0.798  -0.812
245   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   S        -1.054  -1.093  -1.081  -1.036  -1.106  -1.093  -1.092  -1.138  -1.061
248   E        -1.542  -1.606  -1.461  -1.502  -1.593  -1.372  -1.410  -1.452  -1.238
249   D        -2.258  -2.231  -2.037  -1.803  -1.731  -1.472  -1.727  -1.694  -1.439
250   L        -1.542  -1.601  -1.474  -1.669  -1.749  -1.530  -1.410  -1.448  -1.248
251   L         0.077   0.119   0.057  -0.197  -0.127  -0.241  -0.140  -0.071  -0.223
252   K        -0.639  -0.598  -0.610  -0.823  -0.761  -0.715  -0.881  -0.826  -0.786
253   K        -1.542  -1.477  -1.454  -1.526  -1.443  -1.355  -1.410  -1.351  -1.232
254   C        -0.826  -0.773  -0.637  -1.059  -0.993  -0.784  -1.092  -1.017  -0.818
255   S        -1.054  -1.062  -1.075  -1.045  -1.082  -1.070  -1.092  -1.089  -1.052
256   L        -1.054  -0.920  -1.059  -1.059  -0.838  -1.113  -1.092  -0.927  -1.035
257   D        -1.843  -1.876  -1.774  -1.735  -1.839  -1.683  -1.516  -1.536  -1.356
258   S        -0.753  -0.659  -0.611  -0.804  -0.655  -0.594  -0.987  -0.853  -0.782
259   D         1.054   1.070   1.141   1.067   1.090   1.199   1.130   1.153   1.257
260   V         0.399   0.464   0.158   0.361   0.443   0.011   0.389   0.485  -0.037
261   V         0.077   0.031   0.037  -0.065  -0.157  -0.191  -0.140  -0.227  -0.261
262   I         1.054   1.070   1.141   1.022   1.042   1.158   1.130   1.153   1.257
263   T        -0.811  -0.923  -1.048  -0.550  -0.717  -0.910  -0.775  -0.915  -1.022
264   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
265   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
266   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
267   S        -0.224  -0.306  -0.535  -0.058  -0.174  -0.520  -0.246  -0.370  -0.677
268   E        -1.054  -0.998  -1.062  -1.078  -1.004  -1.103  -1.092  -1.030  -1.040
269   N        -0.826  -0.823  -0.654  -1.095  -1.091  -0.829  -1.092  -1.081  -0.840
270   Y         0.399   0.249   0.133   0.575   0.384   0.192   0.389   0.150  -0.082
271   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
272   F         0.399   0.249   0.133   0.586   0.371   0.143   0.389   0.150  -0.082
273   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
274   T        -0.510  -0.478  -0.589  -0.472  -0.428  -0.623  -0.669  -0.625  -0.756
275   E        -0.510  -0.481  -0.576  -0.544  -0.482  -0.658  -0.669  -0.610  -0.738
276   Y        -0.639  -0.616  -0.609  -0.776  -0.777  -0.679  -0.881  -0.857  -0.786
277   I        -0.639  -0.725  -0.615  -0.923  -1.061  -0.890  -0.881  -0.965  -0.793
278   K        -1.127  -1.043  -1.081  -1.162  -1.020  -1.042  -1.198  -1.100  -1.060
279   E        -1.542  -1.421  -1.442  -1.441  -1.259  -1.265  -1.410  -1.276  -1.221
280   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
281   A         0.077   0.139   0.078   0.016   0.107  -0.004  -0.140  -0.035  -0.184
282   V        -0.224  -0.107  -0.512  -0.202  -0.051  -0.614  -0.246  -0.087  -0.645
283   C         0.077   0.139   0.078   0.186   0.288   0.111  -0.140  -0.035  -0.184
284   I         1.054   1.070   1.141   1.022   1.042   1.158   1.130   1.153   1.257
285   N         0.399   0.358   0.144   0.478   0.436   0.152   0.389   0.325  -0.062
286   F         1.054   1.070   1.141   1.182   1.203   1.305   1.130   1.153   1.257
287   A         0.077   0.171   0.066   0.024   0.177  -0.034  -0.140   0.019  -0.206
288   C         0.399   0.486   0.157   0.532   0.638   0.218   0.389   0.516  -0.038
289   T        -1.241  -1.184  -1.096  -1.265  -1.184  -1.025  -1.304  -1.244  -1.076
290   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
291   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
292   F         1.054   1.070   1.141   1.182   1.203   1.305   1.130   1.153   1.257
293   S        -0.811  -0.668  -1.017  -0.634  -0.437  -0.954  -0.775  -0.597  -0.986
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   D        -1.054  -1.077  -1.080  -1.010  -1.064  -1.054  -1.092  -1.127  -1.060
296   D        -1.127  -1.176  -1.079  -1.179  -1.240  -1.084  -1.198  -1.230  -1.059
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   V         0.399   0.358   0.144   0.338   0.281  -0.073   0.389   0.325  -0.062
299   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
300   E        -1.054  -0.920  -1.056  -1.033  -0.832  -1.054  -1.092  -0.932  -1.033
301   K        -0.510  -0.498  -0.584  -0.532  -0.495  -0.591  -0.669  -0.636  -0.748
302   A         1.054   1.070   1.141   1.045   1.062   1.180   1.130   1.153   1.257
303   S        -0.639  -0.598  -0.610  -0.751  -0.689  -0.684  -0.881  -0.826  -0.786
304   L         0.077  -0.022   0.029  -0.197  -0.371  -0.291  -0.140  -0.326  -0.276
305   Y         1.054   1.070   1.141   1.138   1.164   1.265   1.130   1.153   1.257
306   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
307   P         1.054   1.070   1.141   1.140   1.157   1.267   1.130   1.153   1.257
308   M         0.077   0.164   0.084   0.094   0.227   0.097  -0.140   0.007  -0.173
309   T        -0.095  -0.023   0.041  -0.305  -0.183  -0.089  -0.458  -0.327  -0.254
310   G         1.054   1.070   1.141   1.082   1.105   1.214   1.130   1.153   1.257
311   K         1.054   1.070   1.141   0.978   1.003   1.119   1.130   1.153   1.257
312   V         1.054   1.070   1.141   0.947   0.967   1.089   1.130   1.153   1.257
313   T         1.054   1.070   1.141   1.125   1.144   1.253   1.130   1.153   1.257
314   I         1.054   1.070   1.141   1.022   1.042   1.158   1.130   1.153   1.257
315   A         0.077   0.143   0.059   0.001   0.102  -0.058  -0.140  -0.029  -0.218
316   M        -0.224  -0.305  -0.535   0.084  -0.047  -0.459  -0.246  -0.368  -0.677
317   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
318   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
319   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
320   N         1.054   1.070   1.141   1.026   1.052   1.162   1.130   1.153   1.257
321   M        -0.095  -0.023   0.041  -0.368  -0.256  -0.137  -0.458  -0.327  -0.254
322   L        -0.224  -0.409  -0.555  -0.318  -0.587  -0.826  -0.246  -0.502  -0.705
323   R         1.054   1.070   1.141   1.155   1.176   1.281   1.130   1.153   1.257
324   L         1.054   1.070   1.141   0.862   0.888   1.012   1.130   1.153   1.257
325   V        -0.510  -0.476  -0.568  -0.600  -0.525  -0.686  -0.669  -0.603  -0.725
326   R        -2.258  -2.231  -2.037  -2.049  -2.032  -1.731  -1.727  -1.694  -1.439
327   N         0.399   0.358   0.144   0.457   0.413   0.099   0.389   0.325  -0.062
328   V        -1.054  -1.065  -1.072  -1.073  -1.087  -1.075  -1.092  -1.113  -1.052
329   E        -1.957  -1.974  -1.775  -1.898  -1.927  -1.661  -1.621  -1.616  -1.357
330   L        -1.957  -1.946  -1.771  -1.846  -1.815  -1.607  -1.621  -1.599  -1.355
331   S        -1.843  -1.836  -1.765  -1.600  -1.604  -1.539  -1.516  -1.505  -1.349
332   K        -1.542  -1.598  -1.457  -1.440  -1.514  -1.327  -1.410  -1.443  -1.234
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.261  -1.195  -1.099  -1.419  -1.297  -1.193  -1.308  -1.226  -1.077
347   -        -1.261  -1.256  -1.110  -1.373  -1.374  -1.137  -1.308  -1.299  -1.087
348   -        -0.597  -0.544  -0.596  -0.647  -0.568  -0.672  -0.767  -0.691  -0.761
349   -        -1.742  -1.689  -1.491  -1.766  -1.672  -1.394  -1.579  -1.520  -1.262
350   -        -1.256  -1.253  -1.106  -1.412  -1.415  -1.160  -1.316  -1.302  -1.085
351   E        -1.509  -1.422  -1.443  -1.364  -1.240  -1.274  -1.358  -1.261  -1.220
352   K        -2.258  -2.231  -2.037  -2.164  -2.123  -1.846  -1.727  -1.694  -1.439
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q02046
Output conservation file - output/Q02046
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
