1     M         1.050   1.057   1.107   1.259   1.270   1.327   1.118   1.128   1.199
2     S        -1.313  -1.274  -1.166  -1.372  -1.329  -1.126  -1.320  -1.279  -1.109
3     T        -1.313  -1.297  -1.169  -1.430  -1.414  -1.207  -1.320  -1.303  -1.112
4     A        -1.830  -1.774  -1.563  -1.884  -1.773  -1.499  -1.595  -1.544  -1.289
5     T        -1.334  -1.259  -1.169  -1.484  -1.372  -1.254  -1.324  -1.247  -1.109
6     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    T        -0.502  -0.499  -0.635  -0.496  -0.506  -0.741  -0.578  -0.579  -0.768
19    K        -0.502  -0.496  -0.637  -0.548  -0.538  -0.765  -0.578  -0.575  -0.771
20    I        -2.156  -2.109  -1.866  -2.049  -1.979  -1.647  -1.708  -1.668  -1.393
21    Y        -1.624  -1.615  -1.532  -1.557  -1.545  -1.436  -1.426  -1.405  -1.264
22    C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
23    S        -1.196  -1.257  -1.148  -1.209  -1.283  -1.107  -1.214  -1.260  -1.092
24    G        -0.561  -0.496  -0.633  -0.622  -0.529  -0.724  -0.684  -0.596  -0.766
25    L        -1.624  -1.674  -1.543  -1.615  -1.705  -1.500  -1.426  -1.465  -1.274
26    Q        -1.196  -1.134  -1.152  -1.071  -1.002  -0.993  -1.214  -1.145  -1.094
27    C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
28    G        -0.266  -0.390  -0.609  -0.180  -0.349  -0.689  -0.260  -0.427  -0.732
29    R        -0.561  -0.573  -0.653  -0.638  -0.670  -0.753  -0.684  -0.725  -0.795
30    E        -0.871  -0.924  -1.108  -0.736  -0.813  -1.116  -0.790  -0.854  -1.045
31    T        -0.561  -0.651  -0.668  -0.615  -0.771  -0.793  -0.684  -0.813  -0.815
32    S        -1.624  -1.571  -1.517  -1.565  -1.484  -1.432  -1.426  -1.365  -1.251
33    S         0.244   0.120   0.028   0.305   0.113  -0.069   0.176  -0.028  -0.224
34    Q        -1.934  -1.838  -1.829  -1.599  -1.478  -1.467  -1.532  -1.448  -1.367
35    M         0.376   0.434   0.098   0.464   0.529   0.109   0.376   0.459  -0.100
36    K         0.044  -0.025  -0.011  -0.064  -0.157  -0.139  -0.154  -0.279  -0.295
37    C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
38    P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
39    V        -0.561  -0.587  -0.655  -0.640  -0.711  -0.813  -0.684  -0.741  -0.799
40    C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
41    L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
42    K        -0.266  -0.390  -0.609  -0.213  -0.365  -0.698  -0.260  -0.427  -0.732
43    Q        -2.051  -2.055  -1.858  -1.881  -1.903  -1.637  -1.638  -1.634  -1.387
44    G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
45    I        -0.693  -0.677  -0.671  -0.873  -0.862  -0.812  -0.896  -0.883  -0.821
46    V        -2.361  -2.261  -2.109  -2.263  -2.115  -1.906  -1.744  -1.667  -1.460
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    S        -1.120  -1.053  -1.125  -1.100  -1.000  -1.140  -1.108  -1.031  -1.068
49    I        -1.313  -1.287  -1.169  -1.299  -1.266  -1.081  -1.320  -1.298  -1.112
50    F         1.050   1.057   1.107   1.188   1.196   1.263   1.118   1.128   1.199
51    C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
52    D        -1.313  -1.329  -1.168  -1.384  -1.411  -1.165  -1.320  -1.327  -1.111
53    T        -0.561  -0.442  -0.636  -0.437  -0.251  -0.599  -0.684  -0.520  -0.770
54    S        -1.934  -1.988  -1.854  -1.752  -1.860  -1.702  -1.532  -1.575  -1.385
55    C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
56    Y         0.376   0.434   0.098   0.614   0.682   0.206   0.376   0.459  -0.100
57    E        -0.693  -0.649  -0.664  -0.862  -0.798  -0.785  -0.896  -0.850  -0.813
58    N        -1.741  -1.752  -1.546  -1.704  -1.718  -1.424  -1.532  -1.529  -1.276
59    N        -0.561  -0.549  -0.647  -0.539  -0.537  -0.695  -0.684  -0.680  -0.787
60    Y        -0.134  -0.068  -0.009  -0.077   0.042   0.090  -0.472  -0.357  -0.292
61    K        -1.313  -1.308  -1.179  -1.479  -1.463  -1.256  -1.320  -1.317  -1.121
62    A        -2.361  -2.301  -2.108  -2.147  -2.081  -1.802  -1.744  -1.696  -1.459
63    H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
64    K         1.050   1.057   1.107   0.943   0.968   1.043   1.118   1.128   1.199
65    A        -1.430  -1.526  -1.521  -1.236  -1.381  -1.399  -1.214  -1.310  -1.254
66    L        -1.120  -1.072  -1.130  -1.143  -1.064  -1.169  -1.108  -1.042  -1.071
67    H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
68    N        -1.934  -1.888  -1.835  -1.720  -1.663  -1.559  -1.532  -1.492  -1.372
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    A        -1.741  -1.721  -1.545  -1.816  -1.791  -1.512  -1.532  -1.505  -1.275
72    K        -1.624  -1.624  -1.532  -1.655  -1.666  -1.538  -1.426  -1.427  -1.264
73    D         0.244   0.093   0.028   0.311   0.086  -0.044   0.176  -0.074  -0.224
74    G         0.244   0.093   0.028   0.229   0.002  -0.119   0.176  -0.074  -0.224
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    L        -1.430  -1.461  -1.500  -1.244  -1.308  -1.417  -1.214  -1.246  -1.235
79    E        -2.077  -2.062  -1.849  -1.887  -1.879  -1.610  -1.651  -1.634  -1.381
80    G        -0.561  -0.487  -0.642  -0.621  -0.538  -0.755  -0.684  -0.608  -0.782
81    A        -1.624  -1.513  -1.525  -1.596  -1.430  -1.444  -1.426  -1.311  -1.258
82    Y         0.376   0.334   0.087   0.548   0.497   0.100   0.376   0.312  -0.118
83    D        -0.190  -0.173  -0.042  -0.416  -0.389  -0.176  -0.578  -0.551  -0.354
84    P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
85    F         1.050   1.057   1.107   1.188   1.196   1.263   1.118   1.128   1.199
86    P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
87    K        -1.120  -1.141  -1.145  -1.168  -1.191  -1.188  -1.108  -1.129  -1.088
88    F         0.376   0.334   0.087   0.614   0.561   0.188   0.376   0.312  -0.118
89    K        -1.624  -1.637  -1.543  -1.593  -1.598  -1.438  -1.426  -1.438  -1.274
90    Y         0.044   0.022  -0.005   0.119   0.084   0.011  -0.154  -0.195  -0.285
91    S        -0.693  -0.737  -0.662  -0.832  -0.890  -0.755  -0.896  -0.936  -0.811
92    G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
93    K        -2.051  -2.025  -1.852  -2.040  -1.996  -1.753  -1.638  -1.613  -1.384
94    V         0.044   0.141   0.039  -0.052   0.096  -0.085  -0.154   0.007  -0.205
95    K        -0.134  -0.125  -0.033  -0.327  -0.314  -0.196  -0.472  -0.462  -0.338
96    A        -0.134  -0.115  -0.033  -0.389  -0.363  -0.234  -0.472  -0.443  -0.336
97    S        -1.313  -1.223  -1.164  -1.283  -1.168  -1.047  -1.320  -1.217  -1.106
98    Y         1.050   1.057   1.107   1.140   1.153   1.220   1.118   1.128   1.199
99    P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
100   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
101   T        -0.693  -0.682  -0.655  -0.788  -0.746  -0.681  -0.896  -0.861  -0.800
102   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
103   R        -0.693  -0.731  -0.665  -0.826  -0.863  -0.771  -0.896  -0.927  -0.815
104   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
105   Y        -2.361  -2.336  -2.117  -2.100  -2.102  -1.767  -1.744  -1.721  -1.464
106   V         0.376   0.405   0.093   0.424   0.457   0.005   0.376   0.417  -0.109
107   P         0.376   0.334   0.087   0.394   0.340  -0.045   0.376   0.312  -0.118
108   E        -1.313  -1.268  -1.168  -1.511  -1.441  -1.269  -1.320  -1.273  -1.111
109   D        -1.430  -1.437  -1.501  -1.104  -1.125  -1.280  -1.214  -1.221  -1.237
110   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
111   P        -1.196  -1.188  -1.150  -1.361  -1.343  -1.258  -1.214  -1.200  -1.093
112   K        -1.430  -1.479  -1.515  -1.296  -1.355  -1.412  -1.214  -1.264  -1.249
113   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
114   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
115   W        -0.134  -0.068  -0.009  -0.127  -0.023   0.053  -0.472  -0.357  -0.292
116   A         1.050   1.057   1.107   1.026   1.036   1.118   1.118   1.128   1.199
117   A        -1.624  -1.640  -1.531  -1.549  -1.581  -1.443  -1.426  -1.434  -1.263
118   N        -1.120  -1.212  -1.152  -1.054  -1.195  -1.119  -1.108  -1.200  -1.095
119   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
120   L        -1.934  -1.988  -1.854  -1.744  -1.836  -1.654  -1.532  -1.575  -1.385
121   P         0.376   0.298   0.087   0.413   0.311   0.004   0.376   0.257  -0.118
122   V        -0.871  -0.938  -1.107  -0.730  -0.829  -1.101  -0.790  -0.873  -1.044
123   S        -0.871  -0.802  -1.095  -0.686  -0.602  -1.074  -0.790  -0.713  -1.031
124   E         0.376   0.323   0.084   0.411   0.346  -0.025   0.376   0.295  -0.123
125   Q        -0.561  -0.573  -0.642  -0.418  -0.423  -0.573  -0.684  -0.690  -0.779
126   R        -0.747  -0.797  -0.690  -0.924  -0.988  -0.827  -0.958  -1.003  -0.843
127   N        -0.375  -0.535  -0.643  -0.259  -0.501  -0.711  -0.405  -0.624  -0.778
128   D        -0.871  -1.017  -1.127  -0.658  -0.871  -1.060  -0.790  -0.961  -1.066
129   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
130   L        -1.934  -1.772  -1.828  -1.688  -1.468  -1.576  -1.532  -1.385  -1.366
131   N        -1.120  -1.181  -1.147  -1.062  -1.139  -1.100  -1.108  -1.163  -1.088
132   N        -0.266  -0.257  -0.588  -0.190  -0.164  -0.616  -0.260  -0.251  -0.703
133   I         0.376   0.298   0.087   0.414   0.316  -0.009   0.376   0.257  -0.118
134   P        -1.624  -1.634  -1.531  -1.668  -1.703  -1.545  -1.426  -1.435  -1.264
135   I        -1.196  -1.256  -1.144  -1.227  -1.289  -1.087  -1.214  -1.259  -1.087
136   Y        -0.134  -0.068  -0.009  -0.307  -0.201  -0.111  -0.472  -0.357  -0.292
137   K        -1.741  -1.722  -1.546  -1.794  -1.755  -1.486  -1.532  -1.508  -1.276
138   K        -0.886  -0.873  -0.709  -1.206  -1.172  -0.916  -1.108  -1.089  -0.866
139   D        -0.693  -0.641  -0.665  -0.896  -0.809  -0.818  -0.896  -0.828  -0.814
140   Q        -0.561  -0.561  -0.638  -0.552  -0.544  -0.668  -0.684  -0.671  -0.773
141   I        -0.561  -0.656  -0.668  -0.529  -0.664  -0.662  -0.684  -0.817  -0.816
142   K        -0.693  -0.682  -0.664  -0.904  -0.849  -0.809  -0.896  -0.862  -0.810
143   K        -1.120  -1.163  -1.151  -1.199  -1.275  -1.225  -1.108  -1.164  -1.093
144   I        -0.693  -0.681  -0.674  -0.719  -0.687  -0.659  -0.896  -0.889  -0.825
145   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
146   K         1.050   1.057   1.107   0.943   0.968   1.043   1.118   1.128   1.199
147   A        -0.134  -0.068  -0.009  -0.371  -0.257  -0.172  -0.472  -0.357  -0.292
148   C        -0.871  -0.855  -1.104  -0.608  -0.591  -1.015  -0.790  -0.772  -1.041
149   M        -1.741  -1.688  -1.546  -1.645  -1.582  -1.390  -1.532  -1.482  -1.276
150   L        -0.266  -0.132  -0.574  -0.116   0.040  -0.539  -0.260  -0.087  -0.684
151   G        -0.693  -0.675  -0.670  -0.867  -0.852  -0.790  -0.896  -0.879  -0.820
152   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
153   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
154   V         0.044   0.122   0.007  -0.059   0.063  -0.154  -0.154  -0.024  -0.264
155   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
156   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
157   I        -0.561  -0.583  -0.654  -0.617  -0.674  -0.772  -0.684  -0.734  -0.797
158   A        -0.561  -0.564  -0.642  -0.609  -0.607  -0.753  -0.684  -0.678  -0.779
159   A         1.050   1.057   1.107   1.026   1.036   1.118   1.118   1.128   1.199
160   A         0.044   0.086   0.024  -0.027   0.036  -0.081  -0.154  -0.086  -0.232
161   H        -0.561  -0.486  -0.641  -0.529  -0.425  -0.642  -0.684  -0.581  -0.780
162   V        -0.190  -0.177  -0.043  -0.500  -0.480  -0.254  -0.578  -0.558  -0.356
163   R        -0.134  -0.122  -0.030  -0.327  -0.305  -0.187  -0.472  -0.455  -0.331
164   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
165   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
166   I        -0.266  -0.380  -0.603  -0.172  -0.328  -0.688  -0.260  -0.414  -0.725
167   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
168   T         0.376   0.405   0.093   0.423   0.459   0.021   0.376   0.417  -0.109
169   D         0.376   0.334   0.087   0.470   0.416   0.034   0.376   0.312  -0.118
170   E         0.376   0.323   0.084   0.422   0.358   0.003   0.376   0.295  -0.123
171   L         0.044   0.042  -0.010  -0.056  -0.065  -0.183  -0.154  -0.161  -0.294
172   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
173   E        -1.120  -1.180  -1.138  -1.137  -1.213  -1.177  -1.108  -1.159  -1.079
174   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
175   V         0.044   0.086   0.024  -0.054   0.006  -0.114  -0.154  -0.086  -0.232
176   H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
177   N        -1.313  -1.306  -1.166  -1.445  -1.418  -1.221  -1.320  -1.303  -1.108
178   E        -0.134  -0.163  -0.042  -0.380  -0.442  -0.244  -0.472  -0.532  -0.353
179   T        -0.134  -0.068  -0.009  -0.274  -0.150  -0.088  -0.472  -0.357  -0.292
180   I        -0.266  -0.271  -0.592  -0.129  -0.129  -0.575  -0.260  -0.268  -0.710
181   K        -0.134  -0.163  -0.042  -0.447  -0.495  -0.300  -0.472  -0.532  -0.353
182   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
183   G        -0.810  -0.766  -0.694  -0.939  -0.867  -0.784  -1.002  -0.942  -0.846
184   A        -0.266  -0.390  -0.609  -0.119  -0.284  -0.607  -0.260  -0.427  -0.732
185   Y         0.376   0.298   0.087   0.573   0.480   0.167   0.376   0.257  -0.118
186   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
187   S         1.050   1.057   1.107   1.073   1.081   1.160   1.118   1.128   1.199
188   P         0.376   0.298   0.087   0.403   0.299  -0.021   0.376   0.257  -0.118
189   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
190   N         1.050   1.057   1.107   1.073   1.084   1.160   1.118   1.128   1.199
191   Y         1.050   1.057   1.107   1.140   1.153   1.220   1.118   1.128   1.199
192   Y         0.376   0.323   0.084   0.557   0.493   0.120   0.376   0.295  -0.123
193   N        -0.266  -0.390  -0.609  -0.071  -0.238  -0.570  -0.260  -0.427  -0.732
194   F         1.050   1.057   1.107   1.188   1.196   1.263   1.118   1.128   1.199
195   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
196   K         1.050   1.057   1.107   0.943   0.968   1.043   1.118   1.128   1.199
197   S         1.050   1.057   1.107   1.073   1.081   1.160   1.118   1.128   1.199
198   L        -0.693  -0.628  -0.656  -0.862  -0.757  -0.776  -0.896  -0.802  -0.801
199   C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
200   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
201   S         1.050   1.057   1.107   1.073   1.081   1.160   1.118   1.128   1.199
202   V        -0.561  -0.573  -0.642  -0.613  -0.626  -0.748  -0.684  -0.690  -0.779
203   N         1.050   1.057   1.107   1.073   1.084   1.160   1.118   1.128   1.199
204   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
205   V        -0.134  -0.114  -0.030  -0.383  -0.353  -0.227  -0.472  -0.441  -0.332
206   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
207   C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
208   H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
209   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
210   V         0.044   0.101   0.027  -0.067   0.026  -0.120  -0.154  -0.061  -0.227
211   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
212   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
213   K         0.044   0.016  -0.009  -0.064  -0.094  -0.136  -0.154  -0.207  -0.292
214   T        -0.561  -0.481  -0.637  -0.496  -0.378  -0.626  -0.684  -0.574  -0.774
215   V        -0.886  -0.857  -0.698  -1.186  -1.141  -0.889  -1.108  -1.071  -0.853
216   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
217   K        -1.313  -1.342  -1.178  -1.411  -1.436  -1.181  -1.320  -1.342  -1.120
218   E        -0.134  -0.068  -0.009  -0.341  -0.219  -0.147  -0.472  -0.357  -0.292
219   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
220   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
221   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
222   V        -0.561  -0.573  -0.642  -0.613  -0.626  -0.748  -0.684  -0.690  -0.779
223   N         1.050   1.057   1.107   1.073   1.084   1.160   1.118   1.128   1.199
224   L         0.376   0.298   0.087   0.427   0.323  -0.002   0.376   0.257  -0.118
225   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
226   V         1.050   1.057   1.107   1.016   1.022   1.109   1.118   1.128   1.199
227   S        -0.190  -0.175  -0.043  -0.456  -0.438  -0.215  -0.578  -0.555  -0.355
228   L        -0.134  -0.122  -0.030  -0.380  -0.364  -0.224  -0.472  -0.455  -0.331
229   Y         0.376   0.483   0.101   0.573   0.699   0.188   0.376   0.527  -0.094
230   Y        -0.561  -0.651  -0.668  -0.447  -0.592  -0.651  -0.684  -0.813  -0.815
231   Q        -1.624  -1.698  -1.549  -1.438  -1.557  -1.376  -1.426  -1.481  -1.278
232   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
233   Y        -0.561  -0.530  -0.648  -0.357  -0.326  -0.492  -0.684  -0.650  -0.791
234   H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
235   A        -0.561  -0.596  -0.656  -0.600  -0.684  -0.758  -0.684  -0.750  -0.800
236   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
237   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
238   N         1.050   1.057   1.107   1.073   1.084   1.160   1.118   1.128   1.199
239   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
240   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
241   Y         1.050   1.057   1.107   1.140   1.153   1.220   1.118   1.128   1.199
242   Y         1.050   1.057   1.107   1.140   1.153   1.220   1.118   1.128   1.199
243   V         1.050   1.057   1.107   1.016   1.022   1.109   1.118   1.128   1.199
244   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
245   E        -0.134  -0.068  -0.009  -0.341  -0.219  -0.147  -0.472  -0.357  -0.292
246   N        -0.561  -0.448  -0.634  -0.659  -0.474  -0.764  -0.684  -0.523  -0.768
247   I        -0.134  -0.068  -0.009  -0.374  -0.252  -0.176  -0.472  -0.357  -0.292
248   S        -0.871  -0.707  -1.097  -0.794  -0.564  -1.137  -0.790  -0.597  -1.033
249   -        -0.154  -0.105  -0.023  -0.358  -0.274  -0.149  -0.510  -0.424  -0.319
250   -         0.155   0.133   0.028   0.180   0.148  -0.048   0.033  -0.006  -0.225
251   K        -0.693  -0.726  -0.673  -0.934  -0.968  -0.861  -0.896  -0.929  -0.824
252   E        -0.134  -0.092  -0.026  -0.341  -0.265  -0.184  -0.472  -0.401  -0.324
253   A        -1.741  -1.726  -1.543  -1.788  -1.771  -1.489  -1.532  -1.511  -1.274
254   L        -0.561  -0.442  -0.636  -0.613  -0.436  -0.737  -0.684  -0.520  -0.770
255   N        -0.561  -0.666  -0.668  -0.495  -0.653  -0.653  -0.684  -0.824  -0.815
256   T        -0.810  -0.755  -0.694  -0.998  -0.913  -0.836  -1.002  -0.927  -0.846
257   T         0.376   0.434   0.098   0.424   0.492   0.014   0.376   0.459  -0.100
258   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
259   T         0.376   0.298   0.087   0.423   0.324   0.013   0.376   0.257  -0.118
260   S        -0.693  -0.633  -0.667  -0.852  -0.772  -0.774  -0.896  -0.824  -0.817
261   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
262   E        -0.266  -0.380  -0.603  -0.139  -0.287  -0.616  -0.260  -0.414  -0.725
263   C         0.376   0.298   0.087   0.549   0.447   0.107   0.376   0.257  -0.118
264   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
265   K        -1.196  -1.236  -1.159  -1.309  -1.339  -1.220  -1.214  -1.239  -1.101
266   L        -1.120  -1.122  -1.145  -1.174  -1.209  -1.233  -1.108  -1.126  -1.087
267   A         1.050   1.057   1.107   1.026   1.036   1.118   1.118   1.128   1.199
268   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
269   K        -0.871  -0.953  -1.109  -0.767  -0.875  -1.104  -0.790  -0.888  -1.046
270   M        -1.741  -1.716  -1.545  -1.503  -1.497  -1.245  -1.532  -1.503  -1.276
271   C        -0.134  -0.068  -0.009  -0.311  -0.207  -0.115  -0.472  -0.357  -0.292
272   K         1.050   1.057   1.107   0.943   0.968   1.043   1.118   1.128   1.199
273   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
274   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
275   T        -1.196  -1.144  -1.139  -1.298  -1.233  -1.189  -1.214  -1.160  -1.083
276   T        -1.624  -1.623  -1.543  -1.559  -1.567  -1.417  -1.426  -1.426  -1.273
277   F         0.376   0.334   0.087   0.614   0.561   0.188   0.376   0.312  -0.118
278   Q        -0.190  -0.175  -0.043  -0.283  -0.265  -0.060  -0.578  -0.555  -0.355
279   E        -0.810  -0.818  -0.704  -0.960  -0.978  -0.806  -1.002  -1.013  -0.859
280   L         0.044  -0.025  -0.011   0.004  -0.110  -0.090  -0.154  -0.279  -0.295
281   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
282   D        -0.693  -0.682  -0.664  -0.788  -0.752  -0.725  -0.896  -0.862  -0.810
283   H        -1.624  -1.512  -1.523  -1.516  -1.391  -1.339  -1.426  -1.329  -1.257
284   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
285   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
286   K        -0.871  -0.933  -1.112  -0.794  -0.870  -1.161  -0.790  -0.864  -1.050
287   H         0.376   0.334   0.087   0.579   0.524   0.127   0.376   0.312  -0.118
288   A        -0.266  -0.307  -0.593  -0.141  -0.202  -0.632  -0.260  -0.318  -0.711
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   T        -0.693  -0.658  -0.661  -0.917  -0.864  -0.820  -0.896  -0.858  -0.811
293   E        -0.810  -0.818  -0.703  -1.012  -1.026  -0.862  -1.002  -1.014  -0.858
294   N        -0.871  -1.017  -1.127  -0.669  -0.883  -1.097  -0.790  -0.961  -1.066
295   K        -1.196  -1.255  -1.163  -1.260  -1.309  -1.154  -1.214  -1.258  -1.105
296   C        -0.266  -0.380  -0.603  -0.039  -0.198  -0.581  -0.260  -0.414  -0.725
297   S         1.050   1.057   1.107   1.073   1.081   1.160   1.118   1.128   1.199
298   V         1.050   1.057   1.107   1.016   1.022   1.109   1.118   1.128   1.199
299   V         0.044  -0.007  -0.008  -0.059  -0.153  -0.183  -0.154  -0.246  -0.291
300   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
301   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
302   Y         1.050   1.057   1.107   1.140   1.153   1.220   1.118   1.128   1.199
303   C         0.376   0.323   0.084   0.548   0.478   0.098   0.376   0.295  -0.123
304   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
305   H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
306   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
307   V        -0.693  -0.618  -0.657  -0.846  -0.726  -0.734  -0.896  -0.792  -0.800
308   G        -0.190  -0.165  -0.038  -0.470  -0.420  -0.214  -0.578  -0.536  -0.347
309   E        -1.313  -1.278  -1.164  -1.321  -1.239  -1.125  -1.320  -1.269  -1.106
310   F        -1.120  -1.047  -1.139  -1.030  -0.943  -1.048  -1.108  -1.024  -1.079
311   F         1.050   1.057   1.107   1.188   1.196   1.263   1.118   1.128   1.199
312   H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
313   C         1.050   1.057   1.107   1.138   1.148   1.219   1.118   1.128   1.199
314   S        -1.313  -1.322  -1.168  -1.307  -1.329  -1.105  -1.320  -1.320  -1.110
315   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
316   N         0.044   0.021  -0.010   0.019  -0.024  -0.107  -0.154  -0.198  -0.295
317   I         0.376   0.334   0.087   0.413   0.364  -0.011   0.376   0.312  -0.118
318   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
319   H         1.050   1.057   1.107   1.171   1.180   1.248   1.118   1.128   1.199
320   Y         1.050   1.057   1.107   1.140   1.153   1.220   1.118   1.128   1.199
321   A         0.376   0.298   0.087   0.444   0.344   0.030   0.376   0.257  -0.118
322   K        -0.871  -0.944  -1.107  -0.743  -0.829  -1.055  -0.790  -0.878  -1.045
323   N         1.050   1.057   1.107   1.073   1.084   1.160   1.118   1.128   1.199
324   R        -0.190  -0.174  -0.043  -0.471  -0.443  -0.230  -0.578  -0.553  -0.355
325   T        -0.134  -0.068  -0.009  -0.373  -0.254  -0.175  -0.472  -0.357  -0.292
326   P        -0.693  -0.666  -0.670  -0.881  -0.859  -0.817  -0.896  -0.872  -0.821
327   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
328   V        -0.561  -0.624  -0.657  -0.616  -0.719  -0.784  -0.684  -0.767  -0.801
329   M        -0.693  -0.726  -0.673  -0.631  -0.681  -0.596  -0.896  -0.929  -0.824
330   K         0.376   0.298   0.087   0.366   0.283  -0.025   0.376   0.257  -0.118
331   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
332   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
333   M        -0.266  -0.271  -0.592   0.136   0.128  -0.346  -0.260  -0.268  -0.710
334   V        -0.134  -0.163  -0.042  -0.382  -0.453  -0.250  -0.472  -0.532  -0.353
335   F         1.050   1.057   1.107   1.188   1.196   1.263   1.118   1.128   1.199
336   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
337   I         1.050   1.057   1.107   1.004   1.019   1.098   1.118   1.128   1.199
338   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
339   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
340   M         1.050   1.057   1.107   1.259   1.270   1.327   1.118   1.128   1.199
341   I        -0.190  -0.174  -0.043  -0.497  -0.471  -0.250  -0.578  -0.553  -0.355
342   N        -1.430  -1.535  -1.522  -1.190  -1.361  -1.368  -1.214  -1.319  -1.255
343   E        -1.196  -1.134  -1.152  -1.247  -1.161  -1.128  -1.214  -1.145  -1.094
344   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
345   T        -1.624  -1.670  -1.534  -1.624  -1.707  -1.512  -1.426  -1.462  -1.267
346   W        -1.196  -1.249  -1.159  -0.969  -1.042  -0.925  -1.214  -1.252  -1.101
347   K        -0.693  -0.652  -0.658  -0.785  -0.723  -0.691  -0.896  -0.847  -0.806
348   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
349   M        -1.624  -1.633  -1.526  -1.442  -1.457  -1.295  -1.426  -1.425  -1.260
350   T        -0.266  -0.205  -0.589  -0.150  -0.074  -0.617  -0.260  -0.180  -0.706
351   W         1.050   1.057   1.107   1.285   1.295   1.350   1.118   1.128   1.199
352   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
353   D         1.050   1.057   1.107   1.062   1.072   1.150   1.118   1.128   1.199
354   D        -0.693  -0.666  -0.670  -0.803  -0.773  -0.761  -0.896  -0.872  -0.821
355   W         1.050   1.057   1.107   1.285   1.295   1.350   1.118   1.128   1.199
356   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
357   S        -0.134  -0.122  -0.030  -0.320  -0.307  -0.171  -0.472  -0.455  -0.331
358   T        -0.886  -0.873  -0.714  -1.103  -1.093  -0.840  -1.108  -1.090  -0.872
359   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
360   Q        -1.430  -1.528  -1.519  -1.111  -1.272  -1.353  -1.214  -1.312  -1.253
361   D         0.376   0.298   0.087   0.479   0.379   0.060   0.376   0.257  -0.118
362   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
363   K         0.376   0.298   0.087   0.366   0.283  -0.025   0.376   0.257  -0.118
364   L        -2.051  -2.008  -1.843  -1.743  -1.684  -1.465  -1.638  -1.600  -1.378
365   S         0.376   0.323   0.084   0.481   0.410   0.039   0.376   0.295  -0.123
366   A         1.050   1.057   1.107   1.026   1.036   1.118   1.118   1.128   1.199
367   Q         1.050   1.057   1.107   1.204   1.215   1.278   1.118   1.128   1.199
368   F         1.050   1.057   1.107   1.188   1.196   1.263   1.118   1.128   1.199
369   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
370   H         0.044   0.084  -0.004   0.154   0.211   0.043  -0.154  -0.089  -0.284
371   T         0.044   0.086   0.024   0.015   0.074  -0.012  -0.154  -0.086  -0.232
372   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
373   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
374   V         1.050   1.057   1.107   1.016   1.022   1.109   1.118   1.128   1.199
375   T         1.050   1.057   1.107   1.006   1.016   1.099   1.118   1.128   1.199
376   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
377   H        -1.313  -1.217  -1.163  -1.363  -1.229  -1.114  -1.320  -1.214  -1.105
378   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
379   V         0.044   0.022  -0.005  -0.015  -0.056  -0.109  -0.154  -0.195  -0.285
380   E         1.050   1.057   1.107   1.006   1.020   1.099   1.118   1.128   1.199
381   I        -0.134  -0.129  -0.037  -0.387  -0.384  -0.242  -0.472  -0.469  -0.344
382   L         1.050   1.057   1.107   1.020   1.027   1.112   1.118   1.128   1.199
383   T         0.376   0.419   0.096   0.423   0.476   0.028   0.376   0.437  -0.102
384   A         1.050   1.057   1.107   1.026   1.036   1.118   1.118   1.128   1.199
385   R         1.050   1.057   1.107   1.115   1.123   1.198   1.118   1.128   1.199
386   N        -1.120  -1.208  -1.151  -1.061  -1.196  -1.118  -1.108  -1.198  -1.094
387   K        -1.430  -1.479  -1.515  -1.355  -1.426  -1.506  -1.214  -1.264  -1.249
388   K        -1.624  -1.627  -1.542  -1.587  -1.586  -1.427  -1.426  -1.430  -1.272
389   S         1.050   1.057   1.107   1.073   1.081   1.160   1.118   1.128   1.199
390   P         1.050   1.057   1.107   0.996   1.003   1.090   1.118   1.128   1.199
391   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
392   G         1.050   1.057   1.107   0.987   0.997   1.083   1.118   1.128   1.199
393   P         0.376   0.405   0.093   0.406   0.441  -0.005   0.376   0.417  -0.109
394   R        -1.235  -1.226  -1.173  -1.244  -1.265  -1.190  -1.235  -1.232  -1.115
395   Q        -1.235  -1.206  -1.160  -1.193  -1.157  -1.079  -1.235  -1.192  -1.101
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   R         0.244   0.106   0.028   0.360   0.149  -0.011   0.176  -0.052  -0.224
400   I        -0.375  -0.528  -0.643  -0.328  -0.553  -0.754  -0.405  -0.614  -0.778
401   K        -0.020  -0.058  -0.019  -0.240  -0.306  -0.258  -0.266  -0.339  -0.312
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q01662
Output conservation file - output/Q01662
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
