1     M         1.450   1.466   1.538   1.635   1.652   1.762   1.576   1.598   1.705
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.345  -1.299  -1.172  -1.402  -1.290  -1.152  -1.200  -1.152  -0.990
5     N        -0.730  -0.779  -0.717  -0.919  -0.965  -0.854  -0.810  -0.845  -0.742
6     I         0.172   0.100  -0.123   0.334   0.248  -0.075   0.166   0.063  -0.271
7     K        -0.657  -0.688  -0.701  -0.723  -0.774  -0.782  -0.702  -0.722  -0.718
8     D         0.301   0.285   0.374   0.077   0.062   0.196  -0.051  -0.092   0.026
9     R         1.450   1.466   1.538   1.533   1.543   1.665   1.576   1.598   1.705
10    T         1.450   1.466   1.538   1.491   1.506   1.624   1.576   1.598   1.705
11    S        -1.559  -1.580  -1.445  -1.478  -1.534  -1.343  -1.244  -1.248  -1.079
12    E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
13    F         1.450   1.466   1.538   1.578   1.599   1.708   1.576   1.598   1.705
14    Q         0.172   0.042  -0.130   0.223   0.036  -0.196   0.166  -0.021  -0.280
15    Q        -0.415  -0.482  -0.653  -0.373  -0.487  -0.755  -0.376  -0.459  -0.660
16    S        -1.145  -1.185  -1.122  -0.891  -0.945  -0.887  -1.027  -1.050  -0.947
17    V         0.172   0.248  -0.081   0.410   0.533   0.078   0.166   0.269  -0.210
18    L        -0.657  -0.580  -0.671  -0.726  -0.592  -0.755  -0.702  -0.597  -0.683
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    S        -0.844  -0.823  -0.748  -0.971  -0.947  -0.831  -0.919  -0.891  -0.775
21    Y        -1.446  -1.507  -1.437  -1.040  -1.185  -1.105  -1.135  -1.185  -1.071
22    K        -1.259  -1.274  -1.144  -1.306  -1.363  -1.163  -1.135  -1.133  -0.967
23    K         0.301   0.273   0.373   0.167   0.108   0.263  -0.051  -0.116   0.024
24    R        -0.730  -0.667  -0.711  -0.813  -0.730  -0.767  -0.810  -0.745  -0.738
25    N        -0.657  -0.715  -0.721  -0.696  -0.790  -0.786  -0.702  -0.775  -0.745
26    K        -0.415  -0.581  -0.686  -0.235  -0.486  -0.685  -0.376  -0.582  -0.699
27    N        -0.844  -0.844  -0.765  -0.945  -0.942  -0.837  -0.919  -0.915  -0.793
28    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    K        -1.260  -1.256  -1.146  -1.228  -1.234  -1.043  -1.123  -1.115  -0.968
41    E        -0.708  -0.789  -0.744  -0.840  -0.981  -0.917  -0.738  -0.835  -0.765
42    S        -1.345  -1.314  -1.172  -1.562  -1.528  -1.305  -1.200  -1.164  -0.990
43    E        -0.864  -0.820  -0.757  -0.824  -0.754  -0.716  -0.923  -0.869  -0.780
44    N        -0.307  -0.309  -0.271  -0.403  -0.416  -0.386  -0.545  -0.558  -0.490
45    F        -1.260  -1.169  -1.132  -1.165  -1.024  -0.987  -1.123  -1.030  -0.955
46    A        -1.242  -1.152  -1.123  -1.278  -1.168  -1.095  -1.115  -1.032  -0.950
47    N        -0.657  -0.727  -0.720  -0.738  -0.819  -0.818  -0.702  -0.779  -0.745
48    N        -0.356  -0.345  -0.287  -0.310  -0.293  -0.250  -0.593  -0.581  -0.507
49    T        -0.657  -0.617  -0.682  -0.665  -0.612  -0.696  -0.702  -0.649  -0.700
50    T        -1.145  -1.062  -1.094  -1.145  -1.026  -1.059  -1.027  -0.933  -0.921
51    G        -1.259  -1.208  -1.133  -1.188  -1.100  -0.995  -1.135  -1.083  -0.960
52    N        -0.307  -0.342  -0.267  -0.451  -0.490  -0.395  -0.545  -0.580  -0.480
53    G        -0.859  -0.902  -0.784  -0.585  -0.632  -0.473  -0.931  -0.964  -0.810
54    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    S        -1.860  -1.793  -1.708  -1.708  -1.626  -1.520  -1.352  -1.293  -1.163
59    V        -0.114  -0.144  -0.175  -0.068  -0.078  -0.152  -0.268  -0.291  -0.349
60    S         0.795   0.882   0.602   0.755   0.866   0.501   0.817   0.945   0.461
61    E        -0.114  -0.008  -0.192  -0.123   0.010  -0.236  -0.268  -0.128  -0.380
62    F         1.450   1.466   1.538   1.578   1.599   1.708   1.576   1.598   1.705
63    Q        -0.844  -0.852  -0.768  -1.080  -1.092  -0.941  -0.919  -0.917  -0.795
64    K        -0.430  -0.437  -0.309  -0.650  -0.661  -0.460  -0.702  -0.708  -0.538
65    K        -1.145  -1.212  -1.138  -1.067  -1.138  -1.030  -1.027  -1.074  -0.961
66    A         1.450   1.466   1.538   1.434   1.438   1.570   1.576   1.598   1.705
67    S        -0.415  -0.496  -0.647  -0.364  -0.506  -0.711  -0.376  -0.486  -0.653
68    G        -1.559  -1.421  -1.435  -1.473  -1.282  -1.302  -1.244  -1.131  -1.072
69    I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
70    A         0.795   0.677   0.575   0.883   0.718   0.596   0.817   0.623   0.412
71    H        -1.259  -1.260  -1.140  -1.091  -1.100  -0.936  -1.135  -1.122  -0.964
72    E        -0.657  -0.723  -0.707  -0.576  -0.667  -0.649  -0.702  -0.758  -0.725
73    I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
74    S        -0.242  -0.268  -0.229  -0.502  -0.534  -0.465  -0.485  -0.505  -0.440
75    S        -1.559  -1.603  -1.467  -1.419  -1.511  -1.318  -1.244  -1.263  -1.095
76    T         0.172   0.322  -0.068   0.342   0.534  -0.023   0.166   0.372  -0.191
77    A        -0.730  -0.816  -0.740  -0.675  -0.777  -0.628  -0.810  -0.882  -0.766
78    Q        -0.730  -0.784  -0.727  -0.851  -0.928  -0.816  -0.810  -0.852  -0.753
79    L        -0.657  -0.717  -0.733  -0.734  -0.816  -0.816  -0.702  -0.781  -0.758
80    L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
81    S        -0.657  -0.759  -0.733  -0.768  -0.937  -0.863  -0.702  -0.818  -0.758
82    K         0.795   0.785   0.581   0.910   0.904   0.621   0.817   0.797   0.424
83    L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
84    A         0.473   0.447   0.423   0.358   0.290   0.212   0.274   0.218   0.123
85    V        -0.356  -0.221  -0.267  -0.632  -0.404  -0.507  -0.593  -0.399  -0.478
86    L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
87    A         1.450   1.466   1.538   1.434   1.438   1.570   1.576   1.598   1.705
88    K         0.795   0.785   0.581   0.883   0.874   0.560   0.817   0.797   0.424
89    R         0.795   0.677   0.575   0.965   0.800   0.649   0.817   0.623   0.412
90    K         1.450   1.466   1.538   1.469   1.496   1.604   1.576   1.598   1.705
91    P         0.301   0.273   0.373   0.306   0.222   0.368  -0.051  -0.116   0.024
92    M        -0.114   0.038  -0.148  -0.187   0.031  -0.222  -0.268  -0.052  -0.309
93    F         0.473   0.521   0.461   0.494   0.576   0.415   0.274   0.353   0.198
94    N         0.301   0.353   0.413   0.153   0.258   0.316  -0.051   0.041   0.105
95    D         1.450   1.466   1.538   1.562   1.579   1.693   1.576   1.598   1.705
96    N        -0.430  -0.358  -0.287  -0.630  -0.496  -0.401  -0.702  -0.607  -0.508
97    P         1.450   1.466   1.538   1.653   1.671   1.780   1.576   1.598   1.705
98    V         0.473   0.580   0.498   0.456   0.649   0.468   0.274   0.458   0.268
99    E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
100   I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
101   A        -1.259  -1.243  -1.148  -1.232  -1.235  -1.071  -1.135  -1.106  -0.971
102   E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
103   L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
104   S         0.473   0.566   0.500   0.414   0.562   0.422   0.274   0.433   0.272
105   F        -0.114  -0.043  -0.169   0.134   0.246   0.078  -0.268  -0.151  -0.341
106   L        -0.242  -0.254  -0.229  -0.437  -0.404  -0.403  -0.485  -0.481  -0.433
107   I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
108   K         1.450   1.466   1.538   1.469   1.496   1.604   1.576   1.598   1.705
109   R         0.301   0.353   0.413   0.054   0.119   0.228  -0.051   0.041   0.105
110   K        -0.730  -0.752  -0.723  -0.687  -0.713  -0.671  -0.810  -0.820  -0.749
111   I        -0.114  -0.201  -0.236  -0.175  -0.339  -0.402  -0.268  -0.409  -0.442
112   Y        -0.430  -0.358  -0.287  -0.496  -0.419  -0.304  -0.702  -0.607  -0.508
113   A        -1.259  -1.223  -1.148  -1.309  -1.274  -1.131  -1.135  -1.089  -0.971
114   I        -0.114  -0.201  -0.236  -0.175  -0.339  -0.402  -0.268  -0.409  -0.442
115   E         0.301   0.273   0.373   0.044  -0.024   0.118  -0.051  -0.116   0.024
116   Q        -1.145  -1.088  -1.095  -1.215  -1.124  -1.150  -1.027  -0.959  -0.922
117   S        -1.559  -1.603  -1.467  -1.631  -1.659  -1.469  -1.244  -1.263  -1.095
118   L         0.301   0.346   0.396   0.019   0.111   0.149  -0.051   0.028   0.071
119   V        -1.860  -1.826  -1.714  -1.595  -1.552  -1.402  -1.352  -1.319  -1.167
120   Q        -1.559  -1.512  -1.435  -1.687  -1.619  -1.505  -1.244  -1.198  -1.072
121   L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
122   S        -0.114  -0.038  -0.170  -0.295  -0.170  -0.396  -0.268  -0.148  -0.342
123   Q        -0.242  -0.317  -0.235  -0.389  -0.491  -0.359  -0.485  -0.565  -0.448
124   L        -0.657  -0.649  -0.700  -0.621  -0.590  -0.651  -0.702  -0.673  -0.717
125   K        -1.585  -1.556  -1.452  -1.661  -1.623  -1.493  -1.257  -1.227  -1.082
126   K         0.737   0.617   0.548   0.832   0.674   0.560   0.726   0.523   0.362
127   T        -1.112  -1.120  -1.116  -0.870  -0.908  -0.935  -0.974  -0.982  -0.940
128   D        -1.585  -1.583  -1.454  -1.599  -1.638  -1.460  -1.257  -1.249  -1.084
129   V        -1.242  -1.213  -1.125  -1.111  -1.042  -0.944  -1.115  -1.085  -0.952
130   N        -0.768  -0.800  -0.737  -0.835  -0.820  -0.734  -0.832  -0.852  -0.759
131   G        -0.859  -0.753  -0.767  -0.831  -0.681  -0.710  -0.931  -0.813  -0.792
132   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   Q        -0.844  -0.785  -0.748  -0.834  -0.756  -0.673  -0.919  -0.859  -0.773
141   P        -1.559  -1.495  -1.433  -1.320  -1.252  -1.139  -1.244  -1.186  -1.070
142   S        -0.415  -0.295  -0.624  -0.335  -0.182  -0.642  -0.376  -0.227  -0.625
143   A        -0.958  -0.983  -1.054  -0.682  -0.735  -0.841  -0.810  -0.843  -0.880
144   V        -1.446  -1.509  -1.439  -1.147  -1.238  -1.153  -1.135  -1.187  -1.072
145   Q         0.473   0.403   0.422   0.306   0.167   0.194   0.274   0.136   0.122
146   H        -0.415  -0.382  -0.630   0.057   0.071  -0.280  -0.376  -0.348  -0.632
147   S         0.172   0.060  -0.116   0.171   0.021  -0.258   0.166   0.003  -0.260
148   K         0.172   0.118  -0.112   0.315   0.245  -0.128   0.166   0.088  -0.254
149   N         1.450   1.466   1.538   1.348   1.386   1.487   1.576   1.598   1.705
150   V         0.795   0.677   0.575   0.922   0.792   0.604   0.817   0.623   0.412
151   V        -0.242  -0.229  -0.227  -0.374  -0.327  -0.312  -0.485  -0.465  -0.436
152   N        -0.844  -0.891  -0.766  -0.998  -1.036  -0.878  -0.919  -0.954  -0.794
153   L         0.795   0.741   0.579   0.713   0.655   0.393   0.817   0.728   0.419
154   L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
155   N         0.301   0.273   0.373  -0.045  -0.110   0.042  -0.051  -0.116   0.024
156   T        -1.145  -1.212  -1.138  -1.120  -1.194  -1.114  -1.027  -1.074  -0.961
157   Q         0.172   0.185  -0.097   0.295   0.312  -0.141   0.166   0.178  -0.232
158   M         0.301   0.273   0.373   0.195   0.101   0.235  -0.051  -0.116   0.024
159   K        -0.958  -1.052  -1.089  -0.734  -0.883  -0.959  -0.810  -0.912  -0.915
160   N         0.172   0.042  -0.130   0.240   0.086  -0.171   0.166  -0.021  -0.280
161   I        -0.242  -0.281  -0.237  -0.333  -0.365  -0.300  -0.485  -0.527  -0.450
162   S         0.172   0.042  -0.130   0.216   0.053  -0.187   0.166  -0.021  -0.280
163   G        -0.114  -0.220  -0.236   0.040  -0.152  -0.166  -0.268  -0.425  -0.442
164   S        -1.259  -1.221  -1.133  -1.279  -1.222  -1.096  -1.135  -1.093  -0.959
165   F         1.450   1.466   1.538   1.578   1.599   1.708   1.576   1.598   1.705
166   K         0.795   0.785   0.581   0.896   0.888   0.589   0.817   0.797   0.424
167   D         0.473   0.580   0.498   0.493   0.667   0.494   0.274   0.458   0.268
168   V         0.795   0.741   0.579   0.922   0.879   0.611   0.817   0.728   0.419
169   L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
170   E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
171   E        -0.242  -0.212  -0.228  -0.366  -0.314  -0.320  -0.485  -0.435  -0.436
172   R         1.450   1.466   1.538   1.533   1.543   1.665   1.576   1.598   1.705
173   Q         0.301   0.273   0.373   0.030  -0.035   0.140  -0.051  -0.116   0.024
174   R        -0.242  -0.258  -0.231  -0.316  -0.334  -0.296  -0.485  -0.488  -0.440
175   L        -0.114  -0.016  -0.186  -0.236  -0.076  -0.331  -0.268  -0.133  -0.368
176   E        -0.114  -0.220  -0.236  -0.095  -0.266  -0.272  -0.268  -0.425  -0.442
177   M        -1.259  -1.215  -1.143  -1.308  -1.269  -1.150  -1.135  -1.088  -0.967
178   A        -0.415  -0.275  -0.614  -0.220  -0.057  -0.507  -0.376  -0.203  -0.613
179   N         0.301   0.273   0.373  -0.056  -0.111   0.028  -0.051  -0.116   0.024
180   K        -0.356  -0.389  -0.298  -0.485  -0.560  -0.428  -0.593  -0.642  -0.522
181   D        -0.430  -0.434  -0.309  -0.677  -0.693  -0.519  -0.702  -0.705  -0.537
182   R         1.450   1.466   1.538   1.533   1.543   1.665   1.576   1.598   1.705
183   W        -0.657  -0.613  -0.691  -0.437  -0.374  -0.481  -0.702  -0.633  -0.706
184   Q         0.795   0.879   0.598   0.855   0.956   0.563   0.817   0.940   0.454
185   K        -1.145  -1.117  -1.107  -1.065  -1.044  -1.001  -1.027  -0.998  -0.936
186   L        -0.114  -0.016  -0.186  -0.053   0.101  -0.201  -0.268  -0.133  -0.368
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   T        -1.259  -1.202  -1.145  -1.351  -1.211  -1.177  -1.135  -1.075  -0.969
189   T        -0.657  -0.644  -0.693  -0.671  -0.642  -0.679  -0.702  -0.669  -0.709
190   D        -0.657  -0.579  -0.680  -0.717  -0.607  -0.727  -0.702  -0.608  -0.699
191   T        -1.242  -1.164  -1.126  -1.167  -1.039  -1.008  -1.115  -1.040  -0.953
192   G        -0.294  -0.226  -0.239  -0.408  -0.305  -0.304  -0.549  -0.468  -0.451
193   H        -1.585  -1.537  -1.451  -1.516  -1.503  -1.336  -1.257  -1.213  -1.082
194   A        -1.112  -1.108  -1.095  -1.042  -1.002  -1.009  -0.974  -0.974  -0.920
195   P        -1.112  -1.180  -1.127  -0.888  -1.045  -0.949  -0.974  -1.044  -0.950
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   D        -0.958  -0.812  -1.033  -0.840  -0.653  -0.939  -0.810  -0.648  -0.859
199   D        -0.958  -1.007  -1.070  -0.925  -1.025  -1.119  -0.810  -0.864  -0.896
200   Q        -0.657  -0.730  -0.717  -0.732  -0.838  -0.809  -0.702  -0.783  -0.742
201   T        -0.657  -0.702  -0.701  -0.731  -0.792  -0.807  -0.702  -0.737  -0.718
202   Q        -1.145  -1.147  -1.121  -1.176  -1.224  -1.102  -1.027  -1.029  -0.949
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   S         0.172   0.180  -0.093   0.187   0.198  -0.189   0.166   0.172  -0.227
205   N        -0.114  -0.014  -0.187   0.009   0.163  -0.162  -0.268  -0.132  -0.370
206   H         0.172   0.309  -0.082   0.212   0.390  -0.109   0.166   0.354  -0.211
207   A        -1.559  -1.476  -1.442  -1.312  -1.154  -1.173  -1.244  -1.170  -1.077
208   A        -1.559  -1.452  -1.438  -1.336  -1.182  -1.157  -1.244  -1.152  -1.074
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   T        -0.554  -0.460  -0.683  -0.490  -0.362  -0.651  -0.549  -0.432  -0.695
224   T        -0.210  -0.084  -0.196  -0.145   0.057  -0.150  -0.407  -0.228  -0.379
225   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   N        -0.210  -0.193  -0.223  -0.452  -0.381  -0.467  -0.407  -0.365  -0.418
227   N        -0.768  -0.658  -0.723  -0.867  -0.717  -0.745  -0.832  -0.707  -0.745
228   S        -0.768  -0.798  -0.742  -0.914  -0.946  -0.860  -0.832  -0.850  -0.765
229   N         0.172   0.004  -0.135   0.199  -0.018  -0.267   0.166  -0.074  -0.288
230   P         1.450   1.466   1.538   1.653   1.671   1.780   1.576   1.598   1.705
231   F        -0.114  -0.187  -0.204   0.065  -0.040  -0.094  -0.268  -0.355  -0.397
232   M        -1.559  -1.603  -1.467  -1.382  -1.439  -1.245  -1.244  -1.263  -1.095
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   T        -1.559  -1.510  -1.437  -1.469  -1.387  -1.275  -1.244  -1.197  -1.073
237   S        -0.657  -0.717  -0.733  -0.698  -0.767  -0.804  -0.702  -0.781  -0.758
238   L        -1.446  -1.462  -1.446  -1.422  -1.428  -1.428  -1.135  -1.149  -1.078
239   -        -0.200  -0.136  -0.210  -0.061   0.025  -0.129  -0.368  -0.277  -0.396
240   -        -0.864  -0.855  -0.761  -0.929  -0.932  -0.759  -0.923  -0.913  -0.784
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   L        -1.259  -1.214  -1.140  -1.449  -1.390  -1.263  -1.135  -1.087  -0.966
250   D         1.450   1.466   1.538   1.562   1.579   1.693   1.576   1.598   1.705
251   E        -1.559  -1.569  -1.452  -1.408  -1.441  -1.223  -1.244  -1.240  -1.083
252   S        -1.259  -1.242  -1.145  -1.338  -1.325  -1.191  -1.135  -1.111  -0.969
253   S        -0.114  -0.001  -0.184  -0.230  -0.070  -0.331  -0.268  -0.113  -0.367
254   E        -1.860  -1.730  -1.714  -1.653  -1.482  -1.430  -1.352  -1.244  -1.167
255   K        -0.844  -0.732  -0.734  -1.079  -0.888  -0.893  -0.919  -0.789  -0.759
256   N        -1.145  -1.189  -1.119  -1.056  -1.093  -0.996  -1.027  -1.061  -0.947
257   N        -1.860  -1.860  -1.731  -1.417  -1.408  -1.284  -1.352  -1.342  -1.178
258   N        -1.242  -1.231  -1.140  -1.193  -1.143  -1.041  -1.115  -1.093  -0.963
259   S        -1.260  -1.258  -1.151  -1.276  -1.256  -1.099  -1.123  -1.115  -0.973
260   S        -0.307  -0.259  -0.252  -0.513  -0.462  -0.406  -0.545  -0.496  -0.465
261   N         0.067   0.063  -0.146   0.049   0.063  -0.277   0.018   0.007  -0.304
262   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   E        -0.864  -0.854  -0.786  -0.851  -0.871  -0.743  -0.923  -0.912  -0.812
266   L         1.450   1.466   1.538   1.290   1.314   1.432   1.576   1.598   1.705
267   S        -0.307  -0.285  -0.269  -0.509  -0.484  -0.434  -0.545  -0.532  -0.487
268   F        -0.057   0.057  -0.173  -0.131   0.033  -0.300  -0.159   0.003  -0.344
269   P         1.450   1.466   1.538   1.661   1.682   1.788   1.576   1.598   1.705
270   Q        -1.145  -1.134  -1.109  -1.148  -1.141  -1.090  -1.027  -1.016  -0.939
271   N        -0.657  -0.623  -0.697  -0.788  -0.731  -0.852  -0.702  -0.655  -0.717
272   D        -1.145  -1.202  -1.120  -0.904  -0.991  -0.859  -1.027  -1.065  -0.945
273   S        -1.860  -1.853  -1.732  -1.763  -1.721  -1.561  -1.352  -1.337  -1.178
274   Q         1.450   1.466   1.538   1.354   1.362   1.493   1.576   1.598   1.705
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   L         0.411   0.419   0.412   0.243   0.264   0.253   0.159   0.166   0.102
277   M        -0.554  -0.661  -0.704  -0.552  -0.737  -0.767  -0.549  -0.688  -0.719
278   L         0.473   0.443   0.425   0.336   0.300   0.270   0.274   0.210   0.128
279   M         0.246   0.286   0.385   0.028   0.069   0.219  -0.159  -0.091   0.049
280   E         0.795   0.785   0.581   0.850   0.836   0.523   0.817   0.797   0.424
281   E         0.172   0.100  -0.123   0.305   0.203  -0.137   0.166   0.063  -0.271
282   G         0.301   0.312   0.390   0.084   0.083   0.223  -0.051  -0.039   0.058
283   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   N        -1.145  -1.147  -1.121  -1.155  -1.179  -1.081  -1.027  -1.029  -0.949
287   N        -0.356  -0.344  -0.284  -0.577  -0.545  -0.476  -0.593  -0.579  -0.503
288   V        -1.259  -1.223  -1.148  -1.202  -1.125  -1.002  -1.135  -1.089  -0.971
289   Y         1.450   1.466   1.538   1.682   1.705   1.808   1.576   1.598   1.705
290   L        -0.114  -0.220  -0.236  -0.267  -0.410  -0.465  -0.268  -0.425  -0.442
291   Q         1.450   1.466   1.538   1.340   1.347   1.480   1.576   1.598   1.705
292   E         0.246   0.274   0.377  -0.091  -0.064   0.113  -0.159  -0.113   0.033
293   R         1.450   1.466   1.538   1.533   1.543   1.665   1.576   1.598   1.705
294   N        -0.657  -0.783  -0.730  -0.704  -0.853  -0.778  -0.702  -0.837  -0.756
295   R        -1.145  -1.210  -1.119  -1.139  -1.274  -1.151  -1.027  -1.078  -0.947
296   A         0.795   0.741   0.579   0.845   0.757   0.516   0.817   0.728   0.419
297   V         0.301   0.275   0.372   0.140   0.096   0.218  -0.051  -0.111   0.023
298   E         0.795   0.741   0.579   0.855   0.778   0.530   0.817   0.728   0.419
299   T        -0.657  -0.679  -0.721  -0.650  -0.724  -0.801  -0.702  -0.743  -0.745
300   I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
301   E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
302   S         1.450   1.466   1.538   1.320   1.347   1.460   1.576   1.598   1.705
303   T         1.450   1.466   1.538   1.491   1.506   1.624   1.576   1.598   1.705
304   I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
305   Q        -0.242  -0.273  -0.237  -0.509  -0.546  -0.469  -0.485  -0.514  -0.449
306   E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
307   V         0.301   0.273   0.373   0.069   0.011   0.129  -0.051  -0.116   0.024
308   G         1.450   1.466   1.538   1.587   1.601   1.717   1.576   1.598   1.705
309   N        -0.114  -0.244  -0.236  -0.187  -0.368  -0.375  -0.268  -0.446  -0.441
310   L        -0.114  -0.201  -0.236  -0.226  -0.360  -0.378  -0.268  -0.409  -0.442
311   F         1.450   1.466   1.538   1.578   1.599   1.708   1.576   1.598   1.705
312   Q        -0.114  -0.244  -0.236  -0.247  -0.452  -0.435  -0.268  -0.446  -0.441
313   Q         1.450   1.466   1.538   1.340   1.347   1.480   1.576   1.598   1.705
314   L         1.450   1.466   1.538   1.303   1.337   1.445   1.576   1.598   1.705
315   A         1.450   1.466   1.538   1.434   1.438   1.570   1.576   1.598   1.705
316   S        -1.145  -1.222  -1.121  -1.138  -1.257  -1.071  -1.027  -1.086  -0.948
317   M         1.450   1.466   1.538   1.635   1.652   1.762   1.576   1.598   1.705
318   V         1.450   1.466   1.538   1.494   1.542   1.628   1.576   1.598   1.705
319   Q        -0.242  -0.222  -0.228  -0.544  -0.505  -0.488  -0.485  -0.444  -0.431
320   E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
321   Q         1.450   1.466   1.538   1.340   1.347   1.480   1.576   1.598   1.705
322   G        -0.114  -0.244  -0.236   0.019  -0.202  -0.221  -0.268  -0.446  -0.441
323   E         1.450   1.466   1.538   1.442   1.459   1.577   1.576   1.598   1.705
324   V        -0.730  -0.726  -0.713  -0.691  -0.654  -0.643  -0.810  -0.797  -0.738
325   I         0.473   0.437   0.427   0.420   0.365   0.316   0.274   0.199   0.133
326   Q         0.795   0.785   0.581   0.767   0.738   0.469   0.817   0.797   0.424
327   R         1.450   1.466   1.538   1.533   1.543   1.665   1.576   1.598   1.705
328   I         1.450   1.466   1.538   1.440   1.460   1.575   1.576   1.598   1.705
329   D         1.450   1.466   1.538   1.562   1.579   1.693   1.576   1.598   1.705
330   A        -0.958  -0.962  -1.065  -0.775  -0.794  -0.960  -0.810  -0.814  -0.891
331   N         0.795   0.741   0.579   0.815   0.771   0.562   0.817   0.728   0.419
332   V         0.301   0.273   0.373   0.167   0.120   0.253  -0.051  -0.116   0.024
333   D        -0.657  -0.679  -0.690  -0.489  -0.508  -0.531  -0.702  -0.710  -0.705
334   D         0.172   0.121  -0.101   0.433   0.360   0.024   0.166   0.084  -0.238
335   I         0.172   0.121  -0.101   0.289   0.209  -0.130   0.166   0.084  -0.238
336   D        -1.242  -1.288  -1.160  -1.275  -1.337  -1.170  -1.115  -1.144  -0.980
337   L        -0.294  -0.345  -0.260  -0.440  -0.522  -0.402  -0.549  -0.598  -0.477
338   N         1.450   1.466   1.538   1.328   1.365   1.468   1.576   1.598   1.705
339   I         0.172   0.042  -0.130   0.320   0.148  -0.115   0.166  -0.021  -0.280
340   S        -0.844  -0.852  -0.751  -0.835  -0.809  -0.661  -0.919  -0.917  -0.779
341   G         0.172   0.004  -0.135   0.473   0.245   0.019   0.166  -0.074  -0.288
342   A         1.450   1.466   1.538   1.434   1.438   1.570   1.576   1.598   1.705
343   Q         0.795   0.677   0.575   0.768   0.598   0.461   0.817   0.623   0.412
344   R         1.450   1.466   1.538   1.533   1.543   1.665   1.576   1.598   1.705
345   E         0.795   0.677   0.575   0.877   0.720   0.572   0.817   0.623   0.412
346   L         0.737   0.630   0.532   0.654   0.512   0.351   0.726   0.545   0.333
347   L         0.067  -0.090  -0.193   0.070  -0.139  -0.280   0.018  -0.209  -0.372
348   K         1.450   1.466   1.538   1.458   1.488   1.593   1.576   1.598   1.705
349   Y         0.737   0.630   0.532   1.050   0.910   0.742   0.726   0.545   0.333
350   F         0.264   0.299   0.388   0.290   0.356   0.473  -0.124  -0.064   0.055
351   D        -0.294  -0.346  -0.267  -0.342  -0.415  -0.296  -0.549  -0.598  -0.484
352   R        -0.210  -0.149  -0.210  -0.096  -0.005  -0.121  -0.407  -0.307  -0.399
353   I         0.067   0.021  -0.155   0.203   0.143  -0.111   0.018  -0.057  -0.317
354   K        -0.210  -0.084  -0.196  -0.384  -0.194  -0.347  -0.407  -0.228  -0.379
355   S         0.737   0.733   0.548   0.649   0.646   0.352   0.726   0.715   0.362
356   N         1.450   1.466   1.538   1.328   1.365   1.468   1.576   1.598   1.705
357   R         1.450   1.466   1.538   1.546   1.561   1.677   1.576   1.598   1.705
358   W         0.737   0.630   0.532   1.087   0.936   0.755   0.726   0.545   0.333
359   L         0.737   0.733   0.548   0.688   0.690   0.450   0.726   0.715   0.362
360   A        -1.242  -1.263  -1.151  -1.117  -1.166  -0.999  -1.115  -1.124  -0.973
361   A        -0.898  -0.906  -0.772  -1.030  -1.006  -0.810  -0.974  -0.968  -0.797
362   K         1.450   1.466   1.538   1.458   1.488   1.593   1.576   1.598   1.705
363   V         0.411   0.418   0.407   0.308   0.318   0.268   0.159   0.165   0.092
364   F         1.450   1.466   1.538   1.572   1.594   1.702   1.576   1.598   1.705
365   F        -0.210  -0.160  -0.221  -0.078   0.007  -0.111  -0.407  -0.324  -0.415
366   I         0.411   0.504   0.462   0.308   0.462   0.370   0.159   0.324   0.200
367   I        -0.424  -0.353  -0.275  -0.672  -0.531  -0.439  -0.691  -0.591  -0.490
368   F         0.264   0.299   0.388   0.097   0.154   0.287  -0.124  -0.064   0.055
369   V        -0.554  -0.632  -0.706  -0.360  -0.496  -0.602  -0.549  -0.650  -0.722
370   F         1.450   1.466   1.538   1.572   1.594   1.702   1.576   1.598   1.705
371   F         1.450   1.466   1.538   1.572   1.594   1.702   1.576   1.598   1.705
372   V        -0.554  -0.489  -0.663  -0.497  -0.404  -0.627  -0.549  -0.472  -0.671
373   I        -0.210  -0.092  -0.209  -0.409  -0.220  -0.398  -0.407  -0.235  -0.403
374   W         1.450   1.466   1.538   1.732   1.753   1.856   1.576   1.598   1.705
375   V         1.450   1.466   1.538   1.482   1.504   1.616   1.576   1.598   1.705
376   L         1.450   1.466   1.538   1.300   1.327   1.442   1.576   1.598   1.705
377   V         0.737   0.678   0.537   0.836   0.756   0.526   0.726   0.625   0.341
378   N        -0.294  -0.346  -0.267  -0.619  -0.668  -0.541  -0.549  -0.598  -0.484
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/Q01590
Output conservation file - output/Q01590
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
